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coformycin and Leukemia, Lymphoid

coformycin has been researched along with Leukemia, Lymphoid in 49 studies

Research

Studies (49)

TimeframeStudies, this research(%)All Research%
pre-199049 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bradstock, KF; Ganeshaguru, K; Goldstone, AH; Hoffbrand, AV; Janossy, G; Prentice, HG; Smyth, JF; Wonke, B1
Blacklock, H; Ganeshaguru, K; Hoffbrand, AV; Lee, N; Piga, A; Prentice, HG; Russell, NH; Smyth, JF1
Benjamin, RS; Freireich, EJ; Keating, MJ; Plunkett, W1
Jurjus, AR; Ridgeway, A; Witz, IP1
Agarwal, RP; Kufe, DW; Major, PP1
Holcenberg, J; Poplack, DG; Wortmann, RL1
Bagnara, AS; Hershfield, MS1
Hoffbrand, AV; Ma, DD; Webster, AD1
Mier, JW; Parkinson, DR1
Hoffbrand, AV; Ma, DD; Prentice, HG1
Falletta, JM; Hershfield, MS; Kinney, TR; Koller, CA; Kredich, NM; Kurtzberg, J; Mitchell, BS1
Edwards, NL; Koller, CA; Mitchell, BS1
Kalwinsky, D; Murphy, SB; Rivera, G; Stass, S1
Ackland, SP; Bagnara, AS; Hallam, LJ; Van der Weyden, MB; Whiteside, MG1
Simone, JV1
Alexander, L; Chubb, S; Montgomery, JA; Plunkett, W1
Heyn, R; Koller, CA; Mitchell, BS1
Adamson, RH; Chassin, MM; Harrap, KR; Jackman, AL; Johns, DG; Paine, RM; Smyth, JF1
Bakay, B; Kung, FH; Nyhan, WL; Yu, AL2
Blatt, J; Glaubiger, DL; Holcenberg, J; Johns, D; Lipton, JM; Murphy, SB; Poplack, DG; Rivera, G; Sallan, SE; Ungerleider, R; Venner, P1
Coleman, MS; Deibel, MR; Hutton, JJ1
Ganeshaguru, K; Hoffbrand, AV; Lee, N; Piga, A; Prentice, HG; Russell, NH; Smyth, JF1
Blatt, J; Glazer, RI; Holcenberg, JS; Lipton, J; Murphy, SB; Poplack, DG; Rivera, G; Sallan, S; Venner, PM1
Blatt, J; Cohen, LF; Gangji, D; Glazer, RI; Poplack, DG; Riccardi, R; Venner, PM1
Fox, RM; Kefford, RF1
Ganeshaguru, K; Hoffbrand, AV; Murphy, P; Piga, A; Prentice, HG; Russell, NH; Sylwestrowicz, T1
Agarwal, RP; Blatt, J; Holcenberg, J; Lipton, JM; Miser, J; Poplack, DG; Reaman, GH; Sallan, S1
Carlon, GC; Howland, WS; Kahn, RC; Miller, L; Tan, C1
Kelley, WN; Koller, CA; Mitchell, BS1
Alexander, L; Chubb, S; Loo, TL; Plunkett, W1
Davis, MP; Levine, M; Li, CY; Mangan, KF; Mazza, JJ; Neu, LT; O'Brien, J; Rauch, AE; Spiers, AS; Wiltsie, JC1
Brozovic, M; Catovsky, D; Dearden, CE; Ganeshaguru, K; Hoffbrand, AV; Linch, DC; Matutes, E; Mills, M; Traub, N; Williams, HJ1
Alexander, HD; el'Agnaf, MR; Ennis, KE; Markey, G; Morris, TC; Robertson, JH1
Balcerzak, SP; Grever, MR; Kraut, EH; Leiby, JM; Neidhart, JA; Wall, RL; Wilson, HE1
Bellingham, AJ; Hoffbrand, AV; Russell, NH1
Brito-Babapulle, F; Catovsky, D; Galton, D; Huang, D; Lavender, P1
Dillman, RO; Qiao, CN; Yu, AL1
Logan, RA; Smith, NP1
Begleiter, A; Israels, LG; Johnston, JB; Pugh, L1
Ho, AD; Kuse, R; Lauria, F; Mandelli, F; Stryckmans, P; Thaler, J; Willemze, R; Zittoun, R1
Matsumoto, SS; Mendelsohn, J; Yu, AL1
Begleiter, A; Glazer, RI; Israels, LG; Johnston, JB; Pugh, L1
Catovsky, D; Ganeshaguru, K; Ho, AD; Hoffbrand, AV; Piga, A1
Ho, AD; Stryckmans, P; Zittoun, R1
Hershfield, MS; Kurtzberg, J1
Hoffbrand, AV; Prentice, HG; Proctor, S; Smyth, JF1
Hershfield, M; Koller, CA; Mitchell, BS; Sidi, Y1
Plunkett, W1

Reviews

2 review(s) available for coformycin and Leukemia, Lymphoid

ArticleYear
Enzyme patterns in normal lymphocyte subpopulations, lymphoid leukaemias and immunodeficiency syndromes.
    Clinics in haematology, 1982, Volume: 11, Issue:3

    Topics: Adenosine Deaminase; Coformycin; DNA; DNA Nucleotidylexotransferase; Humans; Immunologic Deficiency Syndromes; Leukemia, Lymphoid; Lymphocytes; Nucleotidases; Purine-Nucleoside Phosphorylase

1982
T-lymphocyte malignancies: recent advances in the understanding of their biology, diagnosis and treatment.
    Clinical immunology reviews, 1983, Volume: 2, Issue:1

    Topics: Adult; Animals; Antibodies, Monoclonal; Burkitt Lymphoma; Cats; Cattle; Cell Differentiation; Chickens; Child; Coformycin; Disease Models, Animal; Humans; Interleukin-2; Japan; Leukemia; Leukemia, Lymphoid; Lymphoma; Lymphoproliferative Disorders; Male; Mice; Mice, Inbred AKR; Pentostatin; T-Lymphocytes

1983

Trials

2 trial(s) available for coformycin and Leukemia, Lymphoid

ArticleYear
In vitro and in vivo effect of deoxycoformycin in human T cell leukemia.
    Advances in experimental medicine and biology, 1979, Volume: 122B

    Topics: Child, Preschool; Chromatography, High Pressure Liquid; Clinical Trials as Topic; Coformycin; Deoxyadenosines; Humans; Leukemia, Lymphoid; Male; Pentostatin; Purines; Ribonucleosides; T-Lymphocytes

1979
Inhibition of adenosine deaminase to increase the antitumor activity of adenine nucleoside analogues.
    Annals of the New York Academy of Sciences, 1985, Volume: 451

    Topics: Adenine; Adenosine Deaminase Inhibitors; Adult; Animals; Carcinoma, Ehrlich Tumor; Clinical Trials as Topic; Coformycin; DNA; Drug Evaluation; Drug Synergism; Humans; Leukemia P388; Leukemia, Experimental; Leukemia, Lymphoid; Male; Mice; Nucleoside Deaminases; Pentostatin; Thymidine; Vidarabine

1985

Other Studies

45 other study(ies) available for coformycin and Leukemia, Lymphoid

ArticleYear
Remission induction with adenosine-deaminase inhibitor 2'-deoxycoformycin in Thy-lymphoblastic leukaemia.
    Lancet (London, England), 1980, Jul-26, Volume: 2, Issue:8187

    Topics: Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adult; Child; Coformycin; Female; Humans; Leukemia, Lymphoid; Male; Nucleoside Deaminases; Pentostatin; Phenotype; Ribonucleosides; T-Lymphocytes; Thymus Gland

1980
Therapeutic selectivity of and predication of response to 2'-deoxycoformycin in acute leukaemia.
    Lancet (London, England), 1981, Dec-05, Volume: 2, Issue:8258

    Topics: Acute Disease; Adenosine Deaminase; Adolescent; Adult; Child; Child, Preschool; Coformycin; Conjunctivitis; Female; Hemolysis; Humans; Infant; Kidney; Leukemia; Leukemia, Lymphoid; Liver; Male; Pentostatin; Phenotype; Ribonucleosides; T-Lymphocytes

1981
Modulation of 9-beta-D-arabinofuranosyladenine 5'-triphosphate and deoxyadenosine triphosphate in leukemic cells by 2'-deoxycoformycin during therapy with 9-beta-D-arabinofuranosyladenine.
    Cancer research, 1982, Volume: 42, Issue:5

    Topics: Adult; Arabinonucleotides; Cell Line; Chromatography, High Pressure Liquid; Coformycin; Deoxyadenine Nucleotides; DNA; Drug Therapy, Combination; Humans; Leukemia, Lymphoid; Male; Pentostatin; Ribonucleosides; Vidarabine; Vidarabine Phosphate

1982
2' Deoxycoformycin and human hemopoietic cells in culture.
    Developmental and comparative immunology, 1984,Fall, Volume: 8, Issue:4

    Topics: B-Lymphocytes; Cell Division; Cell Line; Coformycin; DNA; Drug Resistance; Humans; Leukemia, Lymphoid; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Lymphocytes; Pentostatin; Ribonucleosides; T-Lymphocytes

1984
Clinical pharmacology of deoxycoformycin.
    Blood, 1981, Volume: 58, Issue:1

    Topics: Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Adolescent; Adult; Aged; Bronchitis; Coformycin; Coma; Conjunctivitis; Deoxyadenosines; Female; Humans; Kidney Diseases; Leukemia, Lymphoid; Lymphoma; Male; Middle Aged; Mycosis Fungoides; Nucleoside Deaminases; Pentostatin; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Ribonucleosides

1981
Relationship of 5'-nucleotidase activity and antileukemic effect in 2'-deoxycoformycin therapy.
    Cancer treatment reports, 1982, Volume: 66, Issue:2

    Topics: 5'-Nucleotidase; Adenosine Deaminase; Adenosylhomocysteinase; Adolescent; Adult; Coformycin; Humans; Hydrolases; Leukemia, Lymphoid; Nucleotidases; Pentostatin; Ribonucleosides

1982
Mechanism of deoxyadenosine-induced catabolism of adenine ribonucleotides in adenosine deaminase-inhibited human T lymphoblastoid cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1982, Volume: 79, Issue:8

    Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine Deaminase Inhibitors; B-Lymphocytes; Cell Line; Coformycin; Deoxyadenosines; Humans; Kinetics; Leukemia, Lymphoid; Nucleoside Deaminases; Nucleotidases; Pentostatin; T-Lymphocytes

1982
Nucleotide metabolism and enzyme inhibitors in thymic acute lymphoblastic leukaemia.
    Haematology and blood transfusion, 1983, Volume: 28

    Topics: Adenosine Deaminase; Adenosine Deaminase Inhibitors; B-Lymphocytes; Cell Line; Cell Survival; Child; Coformycin; DNA Nucleotidylexotransferase; Humans; Leukemia, Lymphoid; Pentostatin; Purine Nucleotides; Purine-Nucleoside Phosphorylase; T-Lymphocytes; Thymus Neoplasms

1983
S-adenosylhomocysteine catabolism and basis for acquired resistance during treatment of T-cell acute lymphoblastic leukemia with 2'-deoxycoformycin alone and in combination with 9-beta-D-arabinofuranosyladenine.
    Cancer research, 1983, Volume: 43, Issue:7

    Topics: Acute Disease; Adenosine; Adult; Coformycin; Deoxyadenosines; Drug Resistance; Drug Therapy, Combination; Erythrocytes; Homocysteine; Humans; Leukemia, Lymphoid; Lymphocytes; Male; Pentostatin; Ribonucleosides; S-Adenosylhomocysteine; Time Factors; Vidarabine

1983
Deoxyribonucleoside triphosphate accumulation by leukemic cells.
    Blood, 1983, Volume: 62, Issue:2

    Topics: Adenosine Deaminase; Adenosine Triphosphate; Coformycin; Enzyme Inhibitors; Guanosine Triphosphate; Humans; Leukemia, Lymphoid; Lymphocytes; Pentostatin; Thymidine

1983
Phenotypic conversion of acute leukaemia from T-lymphoblastic to myeloblastic induced by therapy with 2'-deoxycoformycin.
    British journal of haematology, 1983, Volume: 55, Issue:2

    Topics: Adenosine Deaminase Inhibitors; Child; Coformycin; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Nucleoside Deaminases; Pentostatin; Ribonucleosides; T-Lymphocytes

1983
The biochemical and clinical consequences of 2'-deoxycoformycin in T cell chronic lymphocytic leukaemia.
    Scandinavian journal of haematology, 1984, Volume: 32, Issue:1

    Topics: Adenosine Deaminase; Adenosine Triphosphate; Adenosylhomocysteinase; AMP Deaminase; Coformycin; Cytotoxicity, Immunologic; Deoxyadenine Nucleotides; Deoxyadenosines; Humans; Hydrolases; Leukemia, Lymphoid; Male; Middle Aged; Pentostatin; Ribonucleosides; T-Lymphocytes

1984
The present of situation in treatment and prognosis of childhood acute lymphocytic leukemia with an outlook for the future.
    Haematologica, 1982, Volume: 67, Issue:3

    Topics: Antibiotics, Antineoplastic; Asparaginase; Bone Marrow Transplantation; Child; Child, Preschool; Coformycin; Cytarabine; Humans; Leukemia, Lymphoid; Naphthacenes; Prednisolone; Prognosis; Teniposide; Vincristine

1982
Comparison of the toxicity and metabolism of 9-beta-D-arabinofuranosyl-2-fluoroadenine and 9-beta-D-arabinofuranosyladenine in human lymphoblastoid cells.
    Cancer research, 1980, Volume: 40, Issue:7

    Topics: Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Antineoplastic Agents; Cells, Cultured; Coformycin; DNA; Dose-Response Relationship, Drug; Humans; Leukemia, Lymphoid; T-Lymphocytes; Vidarabine

1980
Inhibition of adenosine deaminase activity results in cytotoxicity to T lymphoblasts in vivo.
    Blood, 1980, Volume: 56, Issue:3

    Topics: Adenosine; Adolescent; Cell Survival; Coformycin; Deoxyadenosines; Enzyme Inhibitors; Humans; Leukemia, Lymphoid; Male; T-Lymphocytes

1980
The clinical pharmacology of the adenosine deaminase inhibitor 2'-deoxycoformycin.
    Cancer chemotherapy and pharmacology, 1980, Volume: 5, Issue:2

    Topics: Adenosine Deaminase Inhibitors; Adult; Aged; Animals; Coformycin; Dogs; Female; Humans; Kinetics; Leukemia, Lymphoid; Lymphocytes; Male; Middle Aged; Nausea; Neoplasms; Nucleoside Deaminases; Pentostatin; Ribonucleosides; Uric Acid

1980
Effects of 2'-deoxycoformycin on the metabolism of purines and the survival of malignant cells in a patient with T-cell leukemia.
    Cancer research, 1981, Volume: 41, Issue:7

    Topics: Adenosine Deaminase Inhibitors; Cells, Cultured; Child, Preschool; Chromatography, High Pressure Liquid; Coformycin; Deoxyadenosines; DNA; Erythrocytes; Humans; Leukemia, Lymphoid; Leukocyte Count; Male; Pentostatin; Purines; Ribonucleosides; T-Lymphocytes

1981
Phase I study of 2'-deoxycoformycin in acute lymphoblastic leukemia.
    Cancer research, 1981, Volume: 41, Issue:9 Pt 1

    Topics: Adenosine Deaminase Inhibitors; Adolescent; Adult; Child; Child, Preschool; Coformycin; Drug Administration Schedule; Drug Evaluation; Female; Humans; Leukemia, Lymphoid; Liver; Lymphopenia; Male; Nausea; Pentostatin; Prognosis; Ribonucleosides; Vomiting

1981
Effect of adenosine deaminase inhibitors on the apparent rate of phosphorylation of deoxyadenosine.
    Biochemical medicine, 1981, Volume: 25, Issue:3

    Topics: Adenine; Adenosine Deaminase Inhibitors; Cell Line; Coformycin; Deoxyadenosines; Enzyme Inhibitors; Humans; Leukemia, Lymphoid; Nucleoside Deaminases; Pentostatin; Phosphorylation; Vidarabine

1981
Studies on the biochemical sequelae of therapy in Thy-acute lymphoblastic leukaemia with the adenosine deaminase inhibitor 2' deoxycoformycin.
    British journal of haematology, 1981, Volume: 49, Issue:1

    Topics: Adenosine Deaminase; Adenosylhomocysteinase; Adolescent; Adult; Bone Marrow; Coformycin; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Humans; Hydrolases; Leukemia, Lymphoid; Leukocyte Count; Male; Pentostatin; Ribonucleosides; Thymine Nucleotides

1981
Levels of 2'-deoxycoformycin, adenosine, and deoxyadenosine in patients with acute lymphoblastic leukemia.
    Cancer research, 1981, Volume: 41, Issue:11 Pt 1

    Topics: Adenosine; Adolescent; Adult; Child; Child, Preschool; Coformycin; Deoxyadenosines; Drug Evaluation; Female; Humans; Leukemia, Lymphoid; Male; Pentostatin; Ribonucleosides; Time Factors

1981
Cerebrospinal fluid levels of 2'-deoxycoformycin after systemic administration in monkeys.
    Journal of the National Cancer Institute, 1982, Volume: 68, Issue:3

    Topics: Animals; Blood-Brain Barrier; Child; Coformycin; Half-Life; Humans; Injections, Intravenous; Kinetics; Leukemia, Lymphoid; Macaca mulatta; Male; Pentostatin; Ribonucleosides

1982
Deoxycoformycin-induced response in chronic lymphocytic leukaemia: deoxyadenosine toxicity in non-replicating lymphocytes.
    British journal of haematology, 1982, Volume: 50, Issue:4

    Topics: Adenosine Deaminase Inhibitors; Cell Survival; Cells, Cultured; Coformycin; Deoxyadenine Nucleotides; Deoxyadenosines; DNA Replication; Humans; Leukemia, Lymphoid; Lymphocytes; Male; Middle Aged; Pentostatin; Ribonucleosides

1982
The effect of deoxycoformycin and deoxyadenosine on deoxyribonucleotide concentrations in leukaemic cells.
    British journal of haematology, 1982, Volume: 51, Issue:4

    Topics: Bone Marrow; Coformycin; Deoxyadenine Nucleotides; Deoxyadenosines; Deoxyribonucleotides; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Pentostatin; Ribonucleosides; T-Lymphocytes

1982
Clinical pharmacology of 9-beta-D-arabinofuranosyladenine in combination with 2'-deoxycoformycin.
    Cancer research, 1982, Volume: 42, Issue:9

    Topics: Adolescent; Adult; Arabinonucleosides; Child, Preschool; Coformycin; Drug Evaluation; Drug Therapy, Combination; Female; Half-Life; Humans; Hypoxanthines; Kinetics; Leukemia, Lymphoid; Male; Pentostatin; Ribonucleosides; Vidarabine

1982
Acute respiratory failure due to 2'Deoxycoformycin.
    Intensive care medicine, 1982, Volume: 8, Issue:2

    Topics: Acute Disease; Antineoplastic Agents; Child; Coformycin; Humans; Leukemia, Lymphoid; Male; Methylprednisolone; Pentostatin; Positive-Pressure Respiration; Respiratory Insufficiency; Ribonucleosides

1982
Treatment of acute lymphoblastic leukemia with the adenosine deaminase inhibitor 2'-deoxycoformycin.
    Advances in experimental medicine and biology, 1979, Volume: 122B

    Topics: Adenosine Deaminase Inhibitors; Allopurinol; Biological Transport; Coformycin; Humans; Leukemia, Lymphoid; Nucleoside Deaminases; Pentostatin; Ribonucleosides

1979
Biochemical basis of the increased activity of 9-beta-D-arabinofuranosyladenine in the presence of inhibitors of adenosine deaminase.
    Cancer research, 1979, Volume: 39, Issue:9

    Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Arabinonucleotides; Bone Marrow; Cell Line; Coformycin; DNA, Neoplasm; Dose-Response Relationship, Drug; Female; Intestinal Mucosa; Leukemia, Experimental; Leukemia, Lymphoid; Mice; Mice, Inbred Strains; Nucleoside Deaminases; Ribonucleosides; Time Factors; Vidarabine

1979
T-cell chronic lymphocytic leukaemia: anomalous cell markers, variable morphology, and marked responsiveness to pentostatin (2'-deoxycoformycin).
    Scandinavian journal of haematology, 1985, Volume: 34, Issue:1

    Topics: Adult; Antibodies, Monoclonal; Antineoplastic Agents; Coformycin; Epitopes; Humans; Leukemia, Lymphoid; Male; Middle Aged; Pentostatin; Phenotype; Ribonucleosides; T-Lymphocytes; T-Lymphocytes, Helper-Inducer; T-Lymphocytes, Regulatory

1985
Membrane phenotype and response to deoxycoformycin in mature T cell malignancies.
    British medical journal (Clinical research ed.), 1987, Oct-10, Volume: 295, Issue:6603

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Membrane; Coformycin; Cyclophosphamide; Deltaretrovirus Infections; Doxorubicin; Female; Follow-Up Studies; Humans; Leukemia; Leukemia, Lymphoid; Lymphoma; Male; Middle Aged; Pentostatin; Phenotype; Prednisone; Prognosis; Ribonucleosides; Sezary Syndrome; T-Lymphocytes; Vincristine

1987
Successful remission induction with deoxycoformycin in elderly patients with T-helper prolymphocytic leukaemia.
    British journal of haematology, 1986, Volume: 63, Issue:1

    Topics: Aged; Antineoplastic Agents; Cells, Cultured; Coformycin; Colony-Forming Units Assay; Female; Humans; Leukemia, Lymphoid; Lymphocytes; Male; Pentostatin; Ribonucleosides; T-Lymphocytes, Helper-Inducer; Time Factors

1986
Low-dose deoxycoformycin in lymphoid malignancy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1985, Volume: 3, Issue:9

    Topics: Adenosine Deaminase Inhibitors; B-Lymphocytes; Candidiasis; Coformycin; Conjunctivitis; Drug Administration Schedule; Gastrointestinal Diseases; Herpesviridae Infections; Humans; Leukemia, Lymphoid; Liver Function Tests; Lymphoma, Non-Hodgkin; Middle Aged; Nucleoside Deaminases; Pentostatin; Respiratory Tract Infections; Ribonucleosides

1985
Potential use of purine nucleosides and enzyme inhibitors for selective depletion of Thy-lymphoblasts from human bone marrow.
    Leukemia research, 1986, Volume: 10, Issue:3

    Topics: Adenosine Deaminase Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cell Line; Cell Survival; Coformycin; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Guanosine; Hematopoietic Stem Cells; Humans; Leukemia, Lymphoid; Nucleoside Deaminases; Pentostatin; Pentosyltransferases; Purine-Nucleoside Phosphorylase; Ribonucleosides; Tumor Stem Cell Assay

1986
Regression of intracerebral lesions in T prolymphocytic leukaemia treated with intravenous deoxycoformycin.
    European journal of haematology, 1988, Volume: 40, Issue:2

    Topics: Antineoplastic Agents; Brain; Coformycin; Humans; Injections, Intravenous; Leukemia, Lymphoid; Male; Middle Aged; Pentostatin; Ribonucleosides; Tomography, X-Ray Computed

1988
Repeated pentostatin (2'deoxycoformycin)-induced remissions in a patient with advanced chronic lymphocytic leukemia.
    The Western journal of medicine, 1988, Volume: 148, Issue:3

    Topics: Antineoplastic Agents; Coformycin; Humans; Leukemia, Lymphoid; Male; Middle Aged; Pentostatin; Remission Induction; Ribonucleosides

1988
Cutaneous presentation of prolymphocytic leukaemia.
    The British journal of dermatology, 1988, Volume: 118, Issue:4

    Topics: Chlorambucil; Coformycin; Humans; Leukemia, Lymphoid; Leukocyte Count; Male; Middle Aged; Pentostatin; Prednisolone; Skin; Skin Neoplasms

1988
Enhanced cytotoxicity and inhibition of DNA damage repair in irradiated murine L5178Y lymphoblasts and human chronic lymphocytic leukemia cells treated with 2'-deoxycoformycin and deoxyadenosine in vitro.
    Cancer research, 1988, Jul-15, Volume: 48, Issue:14

    Topics: Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Animals; Coformycin; Deoxyadenine Nucleotides; Deoxyadenosines; DNA Damage; DNA Repair; Drug Synergism; Leukemia L5178; Leukemia, Experimental; Leukemia, Lymphoid; Mice; NAD; Pentostatin; Ribonucleosides

1988
Deoxycoformycin in therapy of refractory lymphoid neoplasms.
    Onkologie, 1988, Volume: 11, Issue:1

    Topics: Antineoplastic Agents; B-Lymphocytes; Coformycin; Drug Evaluation; Humans; Leukemia; Leukemia, Hairy Cell; Leukemia, Lymphoid; Lymphoma; Pentostatin; Ribonucleosides; Sezary Syndrome; Skin Neoplasms; T-Lymphocytes

1988
Induction of complete remission in T-cell acute lymphoblastic leukemia with deoxycoformycin (dcf) and 9-beta-D-arabinofuranosyladenine (ara-A).
    Advances in experimental medicine and biology, 1986, Volume: 195 Pt A

    Topics: Adult; Antigens, Surface; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Survival; Coformycin; Drug Administration Schedule; Humans; Leukemia, Lymphoid; Male; Pentostatin; Ribonucleosides; T-Lymphocytes; Vidarabine

1986
Induction of DNA strand breaks in chronic lymphocytic leukemia following treatment with 2'-deoxycoformycin in vivo and in vitro.
    Cancer research, 1987, May-01, Volume: 47, Issue:9

    Topics: Adenosine Deaminase Inhibitors; Aged; Coformycin; Deoxyadenine Nucleotides; Deoxyadenosines; DNA; Humans; Leukemia, Lymphoid; Male; Middle Aged; Monocytes; NAD; Pentostatin; Ribonucleosides

1987
Biochemical mechanisms of deoxycoformycin toxicity in chronic leukemias.
    Leukemia research, 1987, Volume: 11, Issue:10

    Topics: Adenosine Triphosphate; Antineoplastic Agents; Coformycin; Deoxyadenine Nucleotides; Deoxyadenosines; DNA Damage; Humans; Leukemia, Lymphoid; NAD; Pentostatin; Ribonucleosides

1987
Response to deoxycoformycin in mature T cell malignancies.
    British medical journal (Clinical research ed.), 1987, Dec-05, Volume: 295, Issue:6611

    Topics: Antineoplastic Agents; Coformycin; Drug Evaluation; Humans; Leukemia, Lymphoid; Pentostatin; Ribonucleosides; Sezary Syndrome

1987
Determinants of deoxyadenosine toxicity in hybrids between human T- and B- lymphoblasts as a model for the development of drug resistance in T-cell acute lymphoblastic leukemia.
    Cancer research, 1985, Volume: 45, Issue:4

    Topics: Adenine Nucleotides; Antigens, Surface; B-Lymphocytes; Cells, Cultured; Coformycin; Culture Media; Deoxyadenosines; Deoxycytidine Kinase; DNA; Drug Resistance; Humans; Hybrid Cells; Leukemia, Lymphoid; Models, Biological; Pentostatin; T-Lymphocytes

1985
Deoxycoformycin in the treatment of leukemias and lymphomas.
    Annals of the New York Academy of Sciences, 1985, Volume: 451

    Topics: Acute Kidney Injury; Adenosine Deaminase Inhibitors; Adolescent; Adult; Aged; Antineoplastic Agents; Child; Child, Preschool; Coformycin; Female; Humans; Leukemia; Leukemia, Lymphoid; Lymphoma; Male; Middle Aged; Mycosis Fungoides; Pentostatin; Ribonucleosides; T-Lymphocytes

1985
Biochemical consequences of adenosine deaminase inhibition in vivo. Differential effects in acute and chronic T cell leukemia.
    Annals of the New York Academy of Sciences, 1985, Volume: 451

    Topics: Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Adenosylhomocysteinase; Aged; Coformycin; Deoxyadenine Nucleotides; Erythrocytes; Female; Humans; Hydrolases; Leukemia, Lymphoid; Nucleoside Deaminases; Pentostatin; T-Lymphocytes

1985