coenzyme-q10 has been researched along with Idiopathic-Pulmonary-Fibrosis* in 1 studies
1 other study(ies) available for coenzyme-q10 and Idiopathic-Pulmonary-Fibrosis
| Article | Year |
|---|---|
CoQ10 enhances the efficacy of airway basal stem cell transplantation on bleomycin-induced idiopathic pulmonary fibrosis in mice.
Recent studies have demonstrated that airway basal stem cells (BCs) transplantation can ameliorate bleomycin-induced idiopathic pulmonary fibrosis (IPF) through lung regeneration promotion. However, BCs under oxidative stress in the alveolar microenvironment are poor in survival, causing unsatisfied efficacy of BCs transplantation. In this study, we investigated whether Coenzyme Q10(CoQ10) counteracts oxidative stress in the alveolar microenvironment, thus improved the efficacy of BCs transplantation for IPF treatment.. The protective effects of CoQ10 on H. CoQ10 blocked H Topics: Animals; Apoptosis; Bleomycin; Cells, Cultured; Disease Models, Animal; Humans; Idiopathic Pulmonary Fibrosis; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Regeneration; Stem Cell Transplantation; Ubiquinone | 2022 |