Page last updated: 2024-08-17

coenzyme a and Disease Models, Animal

coenzyme a has been researched along with Disease Models, Animal in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19904 (13.33)18.7374
1990's4 (13.33)18.2507
2000's4 (13.33)29.6817
2010's11 (36.67)24.3611
2020's7 (23.33)2.80

Authors

AuthorsStudies
Audam, TN; Bradley, JA; Brittian, KR; Dassanayaka, S; Frank, MW; Fulghum, KL; Garrett, LF; Herczeg, S; Hill, BG; Howard, CM; Jackowski, S; Jones, SP; Merkely, B; Pólos, M; Radovits, T; Uchida, S; Zheng, YW1
Caldwell, RB; Caldwell, RW; Labazi, L; Lemtalsi, T; Rojas, MA; Sandow, P; Santana, I; Xu, Z; Zaidi, SAH1
Frank, MW; Jackowski, S; Rock, CO; Subramanian, C; Yao, J1
Finazzi, D; Khatri, D; Mignani, L; Monti, E; Ritelli, M; Zizioli, D1
Hasegawa, T; Hayashi, N; Himi, N; Miyamoto, O; Nakamura-Maruyama, E; Okabe, N; Sakamoto, I; Tsukamoto, I1
Auciello, G; Beconi, M; Bracacel, E; Ciammaichella, A; Cicero, D; Di Marco, A; Elbaum, D; Fezzardi, P; Gonzalez Paz, O; Harper, S; Malancona, S; Monteagudo, E; Rossetti, I; Vecchi, A1
Hu, Y; Li, H; Li, X; Sun, X; Wang, T; Xu, L; Yang, X; Yu, S; Zhao, B1
Brininger, CM; Call, JA; Corona, BT; Flanagan, KE; Goldman, SM; Greising, SM1
Beconi, MG; Di Marco, A; Elbaum, D; Harper, S; Lyons, KA; Monteagudo, E; Quinton, MS; Vaino, A1
Frank, MW; Jackowski, S; Lee, RE; Rock, CO; Sharma, LK; Subramanian, C; White, SW; Yun, MK1
George, DL; Leu, JI; Murphy, ME1
Alcorn, JF; Beck, ME; Bharathi, SS; Chen, R; Ellis, B; Goetzman, ES; Kagan, VE; Karunanidhi, A; Kosmider, B; Mallampalli, RK; McHugh, KJ; McKinney, RW; Otsubo, C; Skilling, H; Suhrie, KR; Tyurina, YY; Uppala, R; Vockley, J; Yeasted, R; Zuo, YY1
Frank, M; Jackowski, S; Pate, C; Rock, CO; Zano, SP1
Chohnan, S; Goto, T; Hagiya, Y; Kubota, Y; Toyoda, A1
Chang, D; Feng, X; He, L; Li, G; Shi, H; Wang, S; Ye, K1
Al-Rejaie, SS; Al-Shabanah, OA; Al-Yahya, AA; Aleisa, AM; Bakheet, SA; Fatani, AG; Sayed-Ahmed, MM1
Britt, RD; Rogers, LK; Tipple, TE; Welty, SE1
de Jong, J; Hayflick, S; Jackowski, S; Nollen, EA; Rana, A; Sanford, L; Sibon, OC; Siudeja, K; Srinivasan, B; Xu, L1
Day, BJ; Huang, TT; Liang, LP; Patel, M; Rowley, S; Waldbaum, S1
Liang, LP; Patel, M1
Gregory, A; Hayflick, SJ1
Lee, CP; Martens, ME1
Bellasio, R; Tacconi, MT; Visentin, M1
Butterworth, RF; Qureshi, IA; Ratnakumari, L1
Michalak, A; Qureshi, IA1
Acott, P; Crocker, JF; Her, H; Lee, SH; Murphy, MG1
Rogers, LK; Smith, CV; Szczpyka, M; Valentine, CJ1
Angielski, S; Rogulski, J1
Rajacic, Z; Thölen, H; Zimmerli, W1
Appleton, DB; DeVivo, DC1

Reviews

1 review(s) available for coenzyme a and Disease Models, Animal

ArticleYear
Neurodegeneration with brain iron accumulation.
    Folia neuropathologica, 2005, Volume: 43, Issue:4

    Topics: Animals; Brain; Coenzyme A; Disease Models, Animal; Drosophila; Humans; Iron; Mice; Mutation; Nerve Degeneration; Pantothenate Kinase-Associated Neurodegeneration; Phosphotransferases (Alcohol Group Acceptor)

2005

Other Studies

29 other study(ies) available for coenzyme a and Disease Models, Animal

ArticleYear
Cardiac PANK1 deletion exacerbates ventricular dysfunction during pressure overload.
    American journal of physiology. Heart and circulatory physiology, 2021, 10-01, Volume: 321, Issue:4

    Topics: Animals; Aorta; Apoptosis; Arterial Pressure; Coenzyme A; Disease Models, Animal; Energy Metabolism; Female; Fibrosis; Gene Deletion; Humans; Male; Metabolome; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Phosphotransferases (Alcohol Group Acceptor); Transcriptome; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling

2021
Role of acyl-coenzyme A: cholesterol transferase 1 (ACAT1) in retinal neovascularization.
    Journal of neuroinflammation, 2023, Jan-23, Volume: 20, Issue:1

    Topics: Acetyl-CoA C-Acetyltransferase; Animals; Cholesterol; Coenzyme A; Disease Models, Animal; Humans; Infant, Newborn; Lipids; Mice; Mice, Inbred C57BL; Oxygen; Retinal Neovascularization; Retinopathy of Prematurity; Transferases; Triggering Receptor Expressed on Myeloid Cells-1; Vascular Endothelial Growth Factor A

2023
A pantothenate kinase-deficient mouse model reveals a gene expression program associated with brain coenzyme a reduction.
    Biochimica et biophysica acta. Molecular basis of disease, 2020, 05-01, Volume: 1866, Issue:5

    Topics: Animals; Apoptosis Regulatory Proteins; Brain; Brain Chemistry; Coenzyme A; Disease Models, Animal; Female; Gene Expression Profiling; Gene Expression Regulation; Heme; Hemoglobins; Humans; Male; Mice; Mice, Knockout; Neurons; Oxidation-Reduction; Pantothenate Kinase-Associated Neurodegeneration; Phosphotransferases (Alcohol Group Acceptor); Repressor Proteins

2020
Abnormal Vasculature Development in Zebrafish Embryos with Reduced Expression of Pantothenate Kinase 2 Gene.
    Bulletin of experimental biology and medicine, 2020, Volume: 170, Issue:1

    Topics: Animals; Blood Vessels; Coenzyme A; Disease Models, Animal; Embryo, Nonmammalian; Gene Expression Regulation, Developmental; Globus Pallidus; Head; Humans; Morpholinos; Pantothenate Kinase-Associated Neurodegeneration; Phosphotransferases (Alcohol Group Acceptor); Tail; Torso; Tumor Suppressor Protein p53; Zebrafish

2020
The protective effect and mechanism of COA-Cl in acute phase after spinal cord injury.
    Neuroscience research, 2021, Volume: 170

    Topics: Animals; Apoptosis; Coenzyme A; Disease Models, Animal; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Recovery of Function; Spinal Cord; Spinal Cord Injuries

2021
Cyclic Phosphopantothenic Acid Prodrugs for Treatment of Pantothenate Kinase-Associated Neurodegeneration.
    Journal of medicinal chemistry, 2020, 12-24, Volume: 63, Issue:24

    Topics: Animals; Blood-Brain Barrier; Brain; Coenzyme A; Cyclization; Disease Models, Animal; Half-Life; Hepatocytes; Humans; Lipid Droplets; Mice; Mice, Inbred C57BL; Mice, Knockout; Pantothenate Kinase-Associated Neurodegeneration; Pantothenic Acid; Prodrugs; Structure-Activity Relationship

2020
miR-23b Ameliorates nonalcoholic steatohepatitis by targeting Acyl-CoA thioesterases 4.
    Experimental cell research, 2021, 10-01, Volume: 407, Issue:1

    Topics: Animals; Coenzyme A; Disease Models, Animal; Hepatocytes; Lipid Metabolism; Liver; Liver Cirrhosis; Male; Mice, Inbred C57BL; MicroRNAs; Non-alcoholic Fatty Liver Disease; Triglycerides

2021
Impact of volumetric muscle loss injury on persistent motoneuron axotomy.
    Muscle & nerve, 2018, Volume: 57, Issue:5

    Topics: Analysis of Variance; Animals; Axotomy; Cholera Toxin; Citrate (si)-Synthase; Coenzyme A; Disease Models, Animal; Functional Laterality; Male; Motor Neurons; Muscle Contraction; Muscle, Skeletal; Muscular Diseases; Organ Size; Rats; Rats, Inbred Lew; Spinal Cord; Time Factors

2018
Fosmetpantotenate (RE-024), a phosphopantothenate replacement therapy for pantothenate kinase-associated neurodegeneration: Mechanism of action and efficacy in nonclinical models.
    PloS one, 2018, Volume: 13, Issue:3

    Topics: Animals; Blood-Brain Barrier; Cell Line, Tumor; Coenzyme A; Disease Models, Animal; Humans; Macaca fascicularis; Male; Mice, Inbred C57BL; Neurons; Pantothenate Kinase-Associated Neurodegeneration; Pantothenic Acid; Phosphotransferases (Alcohol Group Acceptor); Prodrugs; Rats, Sprague-Dawley; RNA Interference; Species Specificity

2018
A therapeutic approach to pantothenate kinase associated neurodegeneration.
    Nature communications, 2018, 10-23, Volume: 9, Issue:1

    Topics: Adenosine Triphosphate; Allosteric Regulation; Animals; Cells, Cultured; Coenzyme A; Disease Models, Animal; Enzyme Stability; Female; Ligands; Magnesium; Male; Mice, Knockout; Neurons; Organ Specificity; Pantothenate Kinase-Associated Neurodegeneration; Phosphotransferases (Alcohol Group Acceptor); Protein Conformation; Protein Multimerization

2018
Mechanistic basis for impaired ferroptosis in cells expressing the African-centric S47 variant of p53.
    Proceedings of the National Academy of Sciences of the United States of America, 2019, 04-23, Volume: 116, Issue:17

    Topics: Animals; Carbon Tetrachloride; Cells, Cultured; Coenzyme A; Disease Models, Animal; Ferroptosis; Humans; Liver; Mice; Oxidation-Reduction; Polymorphism, Single Nucleotide; Sulfhydryl Compounds; Tumor Suppressor Protein p53

2019
Long-chain acyl-CoA dehydrogenase deficiency as a cause of pulmonary surfactant dysfunction.
    The Journal of biological chemistry, 2014, Apr-11, Volume: 289, Issue:15

    Topics: Acyl-CoA Dehydrogenase, Long-Chain; Adult; Animals; Bronchi; Cell Line, Tumor; Coenzyme A; Disease Models, Animal; Epithelial Cells; Fatty Acids; Female; Homozygote; Humans; Infant; Infant, Newborn; Lipid Metabolism, Inborn Errors; Lung; Lung Diseases; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Oxygen; Phosphatidylcholines; Phosphatidylglycerols; Polymorphism, Genetic; Pulmonary Alveoli; Pulmonary Surfactants

2014
Correction of a genetic deficiency in pantothenate kinase 1 using phosphopantothenate replacement therapy.
    Molecular genetics and metabolism, 2015, Volume: 116, Issue:4

    Topics: Administration, Oral; Amides; Animals; Coenzyme A; Disease Models, Animal; Embryo, Mammalian; Female; Fibroblasts; Gene Expression; Humans; Liver; Male; Mice; Mice, Knockout; Pantothenate Kinase-Associated Neurodegeneration; Pantothenic Acid; Phosphoric Acids; Phosphotransferases (Alcohol Group Acceptor); Primary Cell Culture

2015
Decreased hepatic contents of coenzyme A molecular species in mice after subchronic mild social defeat stress.
    Stress (Amsterdam, Netherlands), 2016, Volume: 19, Issue:2

    Topics: Acetyl Coenzyme A; Animals; Body Weight; Coenzyme A; Depression; Disease Models, Animal; Down-Regulation; Hypothalamus; Liver; Male; Malonyl Coenzyme A; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Stress, Psychological; Weight Gain

2016
Effect of energy compound on skeletal muscle strain injury and regeneration in rats.
    Industrial health, 2008, Volume: 46, Issue:5

    Topics: Adenosine Triphosphate; Animals; Coenzyme A; Cytochromes c; Disease Models, Animal; Energy Metabolism; Male; Muscle, Skeletal; Rats; Rats, Sprague-Dawley; Sprains and Strains; Ubiquinone; Vitamin B 6; Wound Healing

2008
Increased urinary losses of carnitine and decreased intramitochondrial coenzyme A in gentamicin-induced acute renal failure in rats.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2010, Volume: 25, Issue:1

    Topics: Acute Kidney Injury; Adenosine Triphosphate; Animals; Blood Urea Nitrogen; Carnitine; Coenzyme A; Creatinine; Disease Models, Animal; Gentamicins; Kidney; Male; Mitochondria; Rats; Rats, Wistar

2010
Hyperoxia exposure alters hepatic eicosanoid metabolism in newborn mice.
    Pediatric research, 2010, Volume: 67, Issue:2

    Topics: Acute Lung Injury; Animals; Animals, Newborn; Arachidonate 5-Lipoxygenase; Coenzyme A; Cyclooxygenase 2; Disease Models, Animal; Glutathione Disulfide; Hydroxyeicosatetraenoic Acids; Hyperoxia; Liver; Lung; Mice; Mice, Inbred C3H; Oxidative Stress; Prostaglandins; Time Factors; Tyrosine

2010
Impaired Coenzyme A metabolism affects histone and tubulin acetylation in Drosophila and human cell models of pantothenate kinase associated neurodegeneration.
    EMBO molecular medicine, 2011, Volume: 3, Issue:12

    Topics: Acetylation; Animals; Coenzyme A; Disease Models, Animal; Drosophila; Histones; Humans; Pantetheine; Pantothenate Kinase-Associated Neurodegeneration; Protein Processing, Post-Translational; Tubulin

2011
Mitochondrial oxidative stress and epilepsy in SOD2 deficient mice: attenuation by a lipophilic metalloporphyrin.
    Neurobiology of disease, 2012, Volume: 45, Issue:3

    Topics: Aconitate Hydratase; Adenine Nucleotides; Analysis of Variance; Animals; Animals, Newborn; Anticonvulsants; Cerebral Cortex; Chromatography, High Pressure Liquid; Coenzyme A; Disease Models, Animal; Electroencephalography; Epilepsy; Fumarate Hydratase; Glutathione; Glutathione Disulfide; Metalloporphyrins; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; NAD; Oxidative Stress; Superoxide Dismutase; Tyrosine

2012
Seizure-induced changes in mitochondrial redox status.
    Free radical biology & medicine, 2006, Jan-15, Volume: 40, Issue:2

    Topics: Animals; Coenzyme A; Cysteine; Disease Models, Animal; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Glutathione Reductase; Hippocampus; Kainic Acid; Male; Mitochondria; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Sprague-Dawley; Seizures; Status Epilepticus; Time Factors

2006
Fatty acid metabolism in skeletal muscle mitochondria from two strains of dystrophic mice.
    Canadian journal of biochemistry, 1980, Volume: 58, Issue:7

    Topics: Acetylcarnitine; Animals; Carnitine; Carnitine O-Acetyltransferase; Carnitine O-Palmitoyltransferase; Citrate (si)-Synthase; Coenzyme A; Disease Models, Animal; Flavoproteins; Malates; Mice; Mice, Mutant Strains; Mitochondria, Muscle; Muscular Dystrophy, Animal; Palmitoylcarnitine

1980
Reye syndrome model in rats: protection against liver abnormalities by L-carnitine and acetyl-L-carnitine.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 275, Issue:2

    Topics: Acetylcarnitine; Acyl Coenzyme A; Animals; Aspirin; Carnitine; Coenzyme A; Disease Models, Animal; Ketone Bodies; Liver; Male; Mitochondria, Liver; Rats; Reye Syndrome

1995
Effect of sodium benzoate on cerebral and hepatic energy metabolites in spf mice with congenital hyperammonemia.
    Biochemical pharmacology, 1993, Jan-07, Volume: 45, Issue:1

    Topics: Acetyl Coenzyme A; Adenosine Triphosphate; Ammonia; Animals; Benzoates; Benzoic Acid; Brain; Coenzyme A; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamine; Liver; Male; Mice; Mice, Mutant Strains; Ornithine Carbamoyltransferase Deficiency Disease; Time Factors; Urea

1993
Free and esterified coenzyme A in the liver and muscles of chronically hyperammonemic mice treated with sodium benzoate.
    Biochemical and molecular medicine, 1995, Volume: 54, Issue:2

    Topics: Acetyl Coenzyme A; Ammonia; Animals; Benzoates; Benzoic Acid; Chronic Disease; Coenzyme A; Disease Models, Animal; Dose-Response Relationship, Drug; Food Preservatives; Liver; Male; Mice; Mice, Inbred ICR; Muscle, Skeletal; Ornithine Carbamoyltransferase Deficiency Disease

1995
Sequestration of coenzyme A by the industrial surfactant, Toximul MP8. A possible role in the inhibition of fatty-acid beta-oxidation in a surfactant/influenza B virus mouse model for acute hepatic encephalopathy.
    Biochimica et biophysica acta, 1997, Jul-10, Volume: 1361, Issue:1

    Topics: 3-Hydroxyacyl CoA Dehydrogenases; Acetyl Coenzyme A; Acetyl-CoA C-Acyltransferase; Acyl Coenzyme A; Animals; Carbon-Carbon Double Bond Isomerases; Coenzyme A; Coenzyme A Ligases; Disease Models, Animal; Emulsions; Enoyl-CoA Hydratase; Hepatic Encephalopathy; Influenza B virus; Isomerases; Liver; Mice; Organic Chemicals; Racemases and Epimerases; Surface-Active Agents

1997
Effects of hepatotoxic doses of acetaminophen and furosemide on tissue concentrations of CoASH and CoASSG in vivo.
    Chemical research in toxicology, 2000, Volume: 13, Issue:9

    Topics: Acetaminophen; Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Coenzyme A; Disease Models, Animal; Furosemide; Glutathione; Liver; Male; Mass Spectrometry; Mice; Mice, Inbred ICR

2000
Metabolic studies in experimental renal dysfunction resulting from maleate administration.
    Current problems in clinical biochemistry, 1975, Volume: 4

    Topics: Acetoacetates; Animals; Bicarbonates; Calcium; Coenzyme A; Disease Models, Animal; Fanconi Syndrome; Hydrogen-Ion Concentration; Keto Acids; Ketoglutaric Acids; Lactose; Malates; Maleates; Malonates; Mitochondria; Mitochondria, Liver; Oxidative Phosphorylation; Permeability; Rats; Sulfurtransferases

1975
Effect of coenzyme-A, NAD, alpha lipoic-acid and cocarboxylase on survival of rats with galactosamine-induced severe hepatitis.
    Experientia, 1985, Aug-15, Volume: 41, Issue:8

    Topics: Animals; Coenzyme A; Disease Models, Animal; Female; Galactosamine; Hepatitis; Liver Function Tests; NAD; Rats; Rats, Inbred Strains; Thiamine Pyrophosphate; Thioctic Acid

1985
An animal model for the ketogenic diet.
    Epilepsia, 1974, Volume: 15, Issue:2

    Topics: Acetoacetates; Acetyltransferases; Amino Acids; Animals; Blood Glucose; Brain; Calcium; Coenzyme A; Dietary Carbohydrates; Dietary Fats; Disease Models, Animal; Electroshock; Hydroxybutyrate Dehydrogenase; Hydroxybutyrates; Keto Acids; Lipid Metabolism; Male; Phosphates; Potassium; Rats; Seizures; Sodium; Sulfurtransferases

1974