cocaine has been researched along with Recrudescence in 394 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 30 (7.61) | 18.7374 |
| 1990's | 72 (18.27) | 18.2507 |
| 2000's | 96 (24.37) | 29.6817 |
| 2010's | 143 (36.29) | 24.3611 |
| 2020's | 53 (13.45) | 2.80 |
| Authors | Studies |
|---|---|
| Alegre-Zurano, L; Cantacorps, L; Luján, MÁ; Martín-Sánchez, A; Valverde, O | 1 |
| Green, CE; Hasan, KM; Lane, SD; Narayana, PA; Russell, DD; Schmitz, JM; Suchting, R; Weaver, MF | 1 |
| Díaz Batanero, C; Fernández-Calderón, F; Gómez-Bujedo, J; Lorca-Marín, JA; Moraleda-Barreno, E; Pérez-Moreno, PJ | 1 |
| Belin, D; Everitt, BJ; Fouyssac, M; Giuliano, C; Lim, NTY; Peña-Oliver, Y; Puaud, M | 1 |
| Chang, SE; Flagel, SB; Krueger, LD | 1 |
| Badiani, A; Boix, F; Caprioli, D; D'Ottavio, G; Meringolo, M; Milella, MS; Ragozzino, D; Reverte, I; Venniro, M | 1 |
| Farokhnia, M; Ikemoto, S; Leggio, L; Nicolas, C; Shaham, Y; Zlebnik, NE | 1 |
| Banks, ML; Hutsell, BA; Negus, SS | 1 |
| Beardsley, PM; Bowen, C; Campbell, U; Dedic, N; Froger-Colléaux, C; Heal, DJ; Hopkins, SC; Koblan, KS; Synan, C | 1 |
| Dietz, D; Grueter, BA; Huang, Y; Johnson, B; Li, JX; Liu, J; Manz, KM; Neve, R; Robison, AJ; Seaman, R; Vu, J; Wu, R; Zhang, Y | 1 |
| Ding, XY; Han, X; Jing, MY; Li, J; Luo, MM; Song, R; Wu, N; Zhao, TY | 1 |
| Borges, C; Charles, J; Shalev, U | 1 |
| Allocca, G; Cai, L; Chen, B; Ding, W; Dong, Y; Fang, J; Gorczyca, MT; Guo, R; Hines, RL; Huang, YH; Ozsoy, S; Tseng, GC; Wang, Y; Yan, R | 1 |
| Calu, DJ; Keefer, SE; Martin, DA | 1 |
| Bornhoft, KN; Collins, V; Saunders, BT; Sinha, S; Wolff, A | 1 |
| Bai, L; Chen, R; Li, H; Sun, L; Wang, H; Yang, Z; Zhang, J; Zhou, Y | 1 |
| Ball, KT; Edson, H | 1 |
| Knackstedt, LA; Padovan-Hernandez, Y; Rojas, G; Wu, L | 1 |
| Lehmann, CM; Moussawi, K | 1 |
| Arguello, AA; Bal, A; Cho, BR; Gerena, J; Herrera Charpentier, AN; Olekanma, DI; Reeves, CA | 1 |
| Han, Y; Lin, X; Liu, X; Lu, L; Lu, T; Shi, J; Xue, Y; Yuan, K; Zheng, W | 1 |
| Haghparast, A; Karimi-Haghighi, S; Mahmoudi, M; Mozafari, R; Sayehmiri, F | 1 |
| Bordieanu, B; Cole, RD; Haque, IA; Kokane, SS; McGinty, JF; Otis, JM; Ray, CM | 1 |
| Cheer, JF; Engi, SA; Li, Y; Luján, MÁ; Oliver, BL; Wenzel, JM; Young-Morrison, R; Zhang, LY; Zlebnik, NE | 1 |
| Huang, D; Ma, YY | 1 |
| Alammari, N; Cobb, MM; Dietz, DM; Gancarz, AM; Gilbert, K; Hagarty, DP; Kausch, MA; Krieg, B; Russo, J | 1 |
| Fu, Y; Huang, L; Huang, X; Lin, S; Ren, C; So, KF; Tao, Q; Wu, J; Yang, Q; Yang, Y; Yuan, TF | 1 |
| Gao, Y; Huang, S; Liao, Y; Liu, F; Shen, D; Shi, C; Si, Y; Yang, L | 1 |
| Slaker, ML | 1 |
| Gobin, C; Schwendt, M | 1 |
| Castillo, E; Faget, L; Farrell, MR; Hnasko, TS; Huerta, MY; Khanbijian, C; Liu, S; Mahler, SV; Rojas, G; Ruiz, CM; Schoch, H | 1 |
| Carroll, A; Elmer, GI; Hope, BT; Koya, E; L De Ness, G; Laque, A; M Kerr, T; Nedelescu, H; Suto, N; Wagner, GE; Watry, D; Weiss, F | 1 |
| McGovern, DJ; Root, DH | 1 |
| De Luca, M; Hernandez, N; Madsen, KL; Schmidt, HD; Turner, C; Wolfheimer, J | 1 |
| Reissner, KJ; Witt, EA | 1 |
| Hammad, AM; Sari, Y | 1 |
| Gauthier, JM; Hastings, MH; Kantak, KM; Mabry, K; Man, HY; Tran, A | 1 |
| Arguello, AA; Bal, A; Cho, BR; Gerena, J; Herrera Charpentier, AN; Olekanma, DI | 1 |
| Belin, D; Belin-Rauscent, A; Everitt, B; Fouyssac, M; Joshi, DD; Puaud, M | 1 |
| Bellivier, F; Besson, M; Correia, C; Corringer, PJ; Forget, B; Gielen, M; Icick, R; Maskos, U; Prevost, MS; Robert, J; Vorspan, F | 1 |
| Bi, GH; Cao, J; He, Y; Jordan, CJ; Newman, AH; Xi, ZX; You, ZB | 1 |
| An, C; Auerbach, BD; Caccamise, A; Cobb, MM; Dietz, DM; Gancarz, AM; Gobira, PH; Iida, M; Martin, JA; Mitra, S; Neve, RL; Salvi, RJ; Stewart, AF; Wang, ZJ; Werner, CT | 1 |
| Altshuler, RD; Li, X; Shaham, Y; Werner, CT | 1 |
| Kenny, PJ; Lehmann, VE | 1 |
| Dacosta-Sánchez, D; Fernández-Calderón, F; González-Ponce, BM; Lozano-Rojas, OM; Ordóñez-Carrasco, JL; Rojas-Tejada, AJ | 1 |
| Brissette, S; Bruneau, J; Conrod, P; Dubreucq, S; Gazil, G; Jutras-Aswad, D; Mongeau-Pérusse, V; Stip, E | 1 |
| Shen, HW; Shi, J; Yu, ZP; Zhang, LY; Zhang, XQ; Zhou, YQ | 1 |
| Blass, BE; Blattner, KM; Doyle, SM; Esquer, A; Garcia, R; Le, T; Neisewander, JL; Powell, GL; Ruscitti, B; Scott, SN | 1 |
| Carroll, ME | 1 |
| Bossert, JM; Brenner, MB; Drake, OR; Hope, BT; Komer, LE; Lennon, VA; Madangopal, R; Ramsey, LA; Shaham, Y; Tunstall, BJ; Weber, SJ | 1 |
| Knackstedt, LA; Schwendt, M | 1 |
| Epstein, DH; Panlilio, LV; Shaham, Y; Venniro, M | 1 |
| Amaning-Kwarteng, AO; Asif-Malik, A; Canales, JJ; Pei, Y | 1 |
| Bouton, ME; Hammack, SE; Linden, AK; May, V; Miles, OW; Thrailkill, EA | 1 |
| Jones, JL; Phillips, KB; Pitchers, KK; Robinson, TE; Sarter, M | 1 |
| Adhikary, S; Bossert, JM; Cifani, C; Hoots, JK; Martin, J; Minier-Toribio, A; Pelloux, Y; Shaham, Y | 1 |
| Barrett, ST; Bevins, RA; Catalano, I; Chou, S; Lydiatt, M; Pittenger, ST | 1 |
| Broos, N; De Vries, TJ; Pattij, T; Schetters, D; van Mourik, Y | 1 |
| Ahmed, SH; Guillem, K | 1 |
| Dias, N; Janes, AC; Lukas, SE; McCarthy, JM; Shepherd, JM; Zuo, CS | 1 |
| Baker, NL; Brady, KT; Ferland, C; Hyer, JM; McRae-Clark, AL; Moran-Santa Maria, MM; Sherman, BJ | 1 |
| Browning, KO; Craig, AR; Nall, RW; Shahan, TA | 1 |
| Farrell, MR; Mahler, SV; Schoch, H | 1 |
| Dell'Acqua, ML; Guercio, LA; Hofmann, ME; Pierce, RC; Schmidt, HD; Sigman, JS; Swinford-Jackson, SE; Wimmer, ME | 1 |
| Koya, E; Ziminski, JJ | 1 |
| Alberati, D; Behl, B; Bespalov, A; Roßmanith, M; Spanagel, R; Takahashi, TT; Vengeliene, V | 1 |
| Alaghband, Y; Campbell, R; Chitnis, O; Espinoza, M; Hwang, P; Jia, Y; Kwapis, JL; López, AJ; Lynch, G; Matheos, DP; White, AO; Wood, MA | 1 |
| Furbish, AB; Heinsbroek, JA; Peters, J | 1 |
| Belin, D; Belin-Rauscent, A; Everitt, BJ; Hermine, O; Lacoste, J; Moussy, A | 1 |
| Mantsch, JR; Twining, RC | 1 |
| Knackstedt, LA; LaCrosse, AL; Logan, CN | 1 |
| Sgritta, M | 1 |
| Bardo, MT; Beckmann, JS; Hammerslag, LR; Weiss, VG; Yates, JR | 1 |
| Hitchcock, LN; Lattal, KM; Raybuck, JD; Wood, MA | 1 |
| Bellés Añó, L; Dimiziani, A; Ginovart, N; Herrmann, F; Millet, P; Tsartsalis, S | 1 |
| Fredriksson, I; Li, X | 1 |
| Anderson, EM; Cowan, CW; Guzman, D; Maze, I; Nestler, EJ; Self, DW; Sun, H; Taniguchi, M | 1 |
| Bechard, AR; Knackstedt, LA | 1 |
| Bossert, JM; Epstein, DH; Hoots, JK; Hope, BT; Komer, LE; Lennon, VA; Madangopal, R; Shaham, Y; Tunstall, BJ; Weber, SJ | 1 |
| Belin, D; Belin-Rauscent, A; Cocker, PJ; Daniel, ML; Rotge, JY | 1 |
| Marchant, NJ | 1 |
| Arrigoni, G; Carretta, A; Ciriaco, P; Negri, G; Rossetti, F; Sant'Angelo, M | 1 |
| Álvarez, AI; Casas, M; Daigre, C; Díaz-Morán, S; Grau-López, L; Palma-Álvarez, RF; Rodríguez-Cintas, L; Roncero, C; Ros-Cucurull, E | 1 |
| Alpert, N; Beltzer, M; Berretta, S; Boyer-Boiteau, A; El Fakhri, G; Goer, F; Kumar, P; Mechawar, N; Murray, L; Normandin, M; Pilobello, KT; Pizzagalli, DA; Turecki, G; Vitaliano, G; Wooten, D | 1 |
| Barnea-Ygael, N; Keidar, L; Zangen, A; Zilkha, N | 1 |
| Bobadilla, AC; Chioma, VC; Garcia-Keller, C; Kalivas, PW; Monforton, C; Neuhofer, D; Spencer, S | 1 |
| Abel, JM; Bakhti-Suroosh, A; Grant, PA; Lynch, WJ; Nesil, T | 1 |
| Ahmed, SH; Durand, A; Girardeau, P; Guillem, K; Navailles, S; Vouillac-Mendoza, C | 1 |
| Garcia-Keller, C; Gass, J; Kalivas, PW; Melton, S; Monforton, C; Smiley, C | 1 |
| Bu, Q; Cen, X; Guo, W; Long, H; Tian, J; Wang, H; Zhao, Y | 1 |
| Kalivas, P; Post, RM | 1 |
| Barry, SM; Coleman, NT; McGinty, JF; Sun, WL; Whitfield, TW; Zelek-Molik, A | 1 |
| Gipson, CD; Kalivas, PW; Kupchik, YM; Reissner, KJ; Shen, H; Thomas, CA | 1 |
| Kariyeva, E; Peck, JA; Ranaldi, R; Wercberger, R | 1 |
| Gipson, CD; Kalivas, PW; Scofield, MD; Stankeviciute, NM | 1 |
| Brady, KT; Henderson, S; McRae-Clark, AL; Myrick, H; Prisciandaro, JJ | 1 |
| Knackstedt, LA; Schwendt, M; Trantham-Davidson, HL | 1 |
| Everitt, BJ; Murray, JE; Pelloux, Y | 1 |
| Goldman, D; Hodgkinson, C; Hu, Y; Seo, D; Sinha, R; Xu, K | 1 |
| Alraies, MC; Alraiyes, AH; Eisa, N; Shawwa, K | 1 |
| Ben-Shahar, O; Gould, AT; Klugmann, M; Miller, BW; Sacramento, AD; Szumlinski, KK; von Jonquieres, G; Wroten, MG | 1 |
| Cheng, K; Heilig, M; King, CE; Rice, KC; Schank, JR; Schroeder, JP; Sun, H; Weinshenker, D | 1 |
| Bi, GH; Gardner, EL; Li, J; Song, R; Xi, ZX; Yang, RF; Zhang, HY | 1 |
| Aston-Jones, G; Sartor, GC | 1 |
| Cary, MS; Coviello, D; Drapkin, M; Ivey, M; Lynch, KG; McKay, JR; Van Horn, DH | 1 |
| Charnley, JL; Dayas, CV; Dickson, PW; James, MH; Levi, EM; Ong, LK; Quinn, RK; Smith, DW | 1 |
| Aston-Jones, G; Beckley, JT; Deisseroth, K; Kaufling, J; Keistler, CR; Mahler, SV; McGlinchey, EM; Vazey, EM; Wilson, SP; Woodward, JJ | 1 |
| Feltenstein, MW; Moorman, DE; See, RE; Waters, RP; Young, AB | 1 |
| Baker, DA; Lim, Y; Makky, K; Mantsch, JR; McReynolds, JR; Thao, M; Vranjkovic, O | 1 |
| Brown, RM; Kim, JH; Lawrence, AJ; Luikinga, S; Perry, C; Zbukvic, I | 1 |
| Albein-Urios, N; Civit, E; de la Torre, R; Lozano, O; Martinez-Gonzalez, JM; Verdejo-Garcia, A | 1 |
| Maury, E; Salem, OB | 1 |
| Ameri, P; Denegri, A; Murialdo, G; Paparo, F | 1 |
| Espallergues, J; Lüscher, C; O'Connor, EC; Pascoli, V; Terrier, J; Valjent, E | 1 |
| Accardo, M; Fiorelli, A; Rossi, F; Santini, M | 1 |
| Brown, RM; Kalivas, PW; Kupchik, YM; Quintero, GC; Reissner, KJ; Spencer, S; Thomas, CA | 1 |
| Haak, EA; Leeksma, OC; Vos, NS | 1 |
| Chefer, S; Guillem, K; Lu, H; Peoples, LL; Rea, WP; Ross, TJ; Stein, EA; Vaupel, DB; Yang, Y; Zou, Q | 1 |
| Edwards, GL; Freeman, KG; Groves-Chapman, JL; Holmes, PV; Ogbonmwan, YE; Schroeder, JP; Sciolino, NR; Weinshenker, D | 1 |
| Broos, N; De Vries, TJ; Loonstra, R; Pattij, T; Schetters, D; Schoffelmeer, AN; van Mourik, Y | 1 |
| Carroll, ME; Claxton, AB; Regier, PS; Zlebnik, NE | 1 |
| Chen, Y; Li, J; Song, R; Wu, N; Yang, RF | 1 |
| Gipson, CD; Kalivas, PW; Kupchik, YM; Scofield, MD; Smith, AC; Thomas, CA; Wiggins, A | 1 |
| Deehan, GA; Hauser, SR; McBride, WJ; Rodd, ZA; Wilden, JA | 1 |
| Craig, AR; Shahan, TA; Sweeney, MM | 1 |
| Chauvet, C; Duranti, A; Lardeux, MV; Nicolas, C; Solinas, M; Thiriet, N | 1 |
| Casas, M; Corominas-Roso, M; Daigre, C; Grau-Lopez, L; Lopez, MV; Ribases, M; Rodríguez-Cintas, L; Roncero, C; Ros-Cucurull, E; Sanchez-Mora, C | 1 |
| Czoty, PW; Gould, RW; Kromrey, SA; Nader, MA | 1 |
| Badiani, A; Contu, L; De Luca, MT; Meringolo, M; Montanari, C; Stendardo, E | 1 |
| Goldberg, SR; Justinova, Z; Le Foll, B; Markou, A; Redhi, GH | 1 |
| Bao, YP; Ding, ZB; Han, Y; Jian, M; Liu, JF; Lu, L; Luo, YX; Shaham, Y; Shen, HW; Shi, HS; Shi, J; Wu, P; Xue, YX; Zhu, WL | 1 |
| Marinelli, M; Wong, WC | 1 |
| Albein-Urios, N; Contreras-Rodríguez, O; Fernández-Serrano, MJ; Lozano-Rojas, O; Martínez-Gonzalez, JM; Perales, JC; Verdejo-García, A; Vilar-López, R | 1 |
| Godfrey, JR; Manvich, DF; Stowe, TA; Weinshenker, D | 1 |
| Ai, S; Li, J; Liang, J; Lu, L; Luo, Y; Meng, S; Shen, H; Shi, J; Sun, C; Wu, P; Xue, Y; Zhang, Y; Zhu, W | 1 |
| Korswagen, LA; Pennings, E; Tervaert, JW; van der Veer, T | 1 |
| Clark, JK; Keefe, K; Kesner, RP; Kirk, RA; Moore, A | 1 |
| Aston-Jones, G; Bentzley, BS | 1 |
| Castagné, V; Froger-Colléaux, C | 1 |
| Dong, Y; Huang, Y; Ma, YY; Marie, H; Nestler, EJ; Schlüter, OM; Wang, X | 1 |
| Abel, J; Beiter, RM; Lynch, WJ; Peterson, AB | 1 |
| Diana, MA; Mameli, M; Meye, FJ; Schwarz, MK; Smit, T; Soiza-Reilly, M | 1 |
| Bradshaw, H; Chiou, LC; Hung, MS; Hwang, LL; Lee, HJ; Lee, YH; Leishman, E; Lu, GL; Mackie, K; Tung, LW; Yu, L; Zimmer, A | 1 |
| Cannella, N; Spanagel, R; Takahashi, T; Vengeliene, V | 1 |
| Adhikary, S; Bonci, A; Bossert, JM; Fredriksson, I; Shaham, Y; Steensland, P; Vendruscolo, LF | 1 |
| Collins, GT; France, CP; Gerak, LR | 1 |
| Garcia-Keller, C; Heinsbroek, JA; Kalivas, PW; Mulvaney, M; Roberts-Wolfe, D; Sorrell, A; Spencer, S | 1 |
| Cunningham, KA; Denner, L; Dineley, KT; Fox, RG; Lane, SD; Miller, WR; Stutz, SJ | 1 |
| Byrne, D; Mahabir, S; Sandys, V; Wynne, B | 1 |
| Allen, NP; Boger, HA; Garcia-Keller, C; Gipson, CD; Griffin, WC; Heinsbroek, JA; Kalivas, PW; Lorang, MR; Neuhofer, D; Roberts-Wolfe, DJ; Scofield, MD; Smith, ACW; Smith, RJ; Spencer, S; Stankeviciute, NM | 1 |
| Auber, A; Goldberg, SR; Justinova, Z; Panlilio, LV; Redhi, GH; Schindler, CW; Schwarcz, R; Secci, ME; Thorndike, EB | 1 |
| Spanagel, R; Takahashi, TT; Vengeliene, V | 1 |
| Bossert, JM; Crombag, HS; Koya, E; Shaham, Y | 1 |
| Erb, S; Kupferschmidt, DA; Tribe, E | 1 |
| Ashby, CR; Gardner, EL; Li, J; Li, X; Millan, MJ; Mocaër, E; Muńoz, C; Peng, XQ; Spiller, K; Thomasson, N; Xi, ZX | 1 |
| Diehl, A; Kiefer, F; Mutschler, J | 1 |
| Butler, VJ; Everitt, BJ; Gardner, RJ; Lee, JL | 1 |
| Kalivas, PW; Knackstedt, LA | 1 |
| Henry, PK; Howell, LL | 1 |
| Self, DW; Simmons, D | 1 |
| Frantz, KJ; Li, C | 1 |
| Kaskutas, LA | 1 |
| Creton, C; Engblom, D; Halbout, B; Lüscher, C; Mameli, M; Parkitna, JR; Spanagel, R | 1 |
| Ali, PK; Rebec, GV; Sari, Y; Smith, KD | 1 |
| Dykstra, LA; Rosenberg, M; Walker, EA; Ward, SJ | 1 |
| Bell, GH; Fuchs, RA; Lasseter, HC; Ramirez, DR; Traina, SA; Xie, X | 1 |
| Bell, GH; Eaddy, JL; Fuchs, RA; Ramirez, DR; Su, ZI | 1 |
| Bigelow, GE; Donny, EC; Nuzzo, PA; Umbricht, A; Walsh, SL | 1 |
| Fuchs, RA; Lasseter, HC; Ramirez, DR; Xie, X | 1 |
| Barker, DJ; Fabbricatore, AT; Ma, S; Pawlak, AP; Root, DH; West, MO | 1 |
| Aguilar, MA; Lluch, J; Miñarro, J; Ribeiro Do Couto, B; Rodríguez-Arias, M | 1 |
| Anker, JJ; Carroll, ME | 2 |
| Erb, S | 1 |
| Robinson, TE; Saunders, BT | 1 |
| Carroll, KM; Ding, YS; Ide, JS; Li, CS; Luo, X; Malison, RT; Rounsaville, BJ; Sinha, R; Zhang, S | 1 |
| De Vries, TJ; Schetters, D; Schoffelmeer, AN; van Gaalen, MM | 1 |
| Beales, M; Conrad, KL; Cotterly, LM; Ford, KA; Marinelli, M; McCutcheon, JE | 1 |
| Epstein, DH; Preston, KL | 1 |
| Kelamangalath, L; Wagner, JJ | 1 |
| Kantak, KM; Mashhoon, Y; Wells, AM | 1 |
| Basarici, I; Kucuk, M; Yildirim, AB | 1 |
| Bonnavion, P; Cannella, N; Ciccocioppo, R; de Lecea, L; Economidou, D; Heilig, M; Kallupi, M; Marugan, J; Massi, M; Ruggeri, B; Ubaldi, M; Weiss, F | 1 |
| Agusti-Mejias, A; Alegre, V; García, R; Messeguer, F; Sánchez, JL | 1 |
| Corcoran, S; Cuthbert, B; Duncan, E; Hollis, J; Norrholm, SD; Sternberg, M | 1 |
| Brown, ZJ; Erb, S; Kupferschmidt, DA | 2 |
| Rebec, GV; Steketee, JD; Sun, W; Xue, Y | 1 |
| Do, PH; Kalivas, PW; Moussawi, K; Reichel, CM; See, RE | 1 |
| Kourrich, S; Rothwell, PE; Thomas, MJ | 1 |
| Fuchs, RA; Lasseter, HC; Ponds, KL; Ramirez, DR; Wells, AM; Xie, X | 1 |
| Lu, L; Rebec, GV; Steketee, JD; Sun, W; Xue, Y | 1 |
| Charnley, JL; Dayas, CV; Flynn, JR; James, MH; Smith, DW | 1 |
| Ambrosio, E; Botreau, F; Coria, SM; Del Olmo, N; Higuera-Matas, A; Miguéns, M; Olías, O | 1 |
| Kalivas, BC; Kalivas, PW; Kolokithas, R; Kupchik, YM; Moussawi, K; Ogburn, KB; Tang, XC; Wang, X | 1 |
| Kalivas, PW; Knackstedt, L; Moussawi, K; Shen, H; Wang, X | 1 |
| Aguirre, A; Bernal, A; Burillo-Putze, G; Busca, P; Casañas, X; Clemente, C; Echarte, JL; Galicia, M; García-Pérez, C; Gil, E; Iglesias, ML; Mirò, Ò; Nogué, S; Puente, I; Puiguriguer, J; Supervía, A | 1 |
| Fischer-Smith, KD; Houston, AC; Rebec, GV | 1 |
| Choi, SM; Jang, EY; Kim, HY; Lee, BH; Steffensen, SC; Yang, CH; Yang, EJ; Yoon, SS | 1 |
| Bao, YP; Chen, C; Ding, ZB; Epstein, DH; Lu, L; Luo, YX; Shaham, Y; Shi, HS; Shi, J; Wu, P; Xue, LF; Xue, YX; Zhu, WL | 1 |
| Baldwin, CK; Buffalari, DM; See, RE | 1 |
| Baker, DA; Kau, KS; Kong, L; Lutgen, V; Madayag, A; Mantsch, JR | 1 |
| Grigson, PS; Nyland, JE | 1 |
| Deschaux, O; Diaz-Aguilar, L; George, O; Koob, GF; Mandyam, CD; Schlosburg, JE; Sobieraj, JC; Vendruscolo, LF; Yuan, CJ | 1 |
| Nishikawa, T | 1 |
| Grimm, JW; Hope, BT; Shaham, Y | 1 |
| Di Ciano, P; Everitt, BJ | 1 |
| Brown, SB; Dudish-Poulsen, S; Hatsukami, DK; Sofuoglu, M | 1 |
| Kalivas, PW; Lapish, CC; McFarland, K | 1 |
| Fuchs, RA; Middaugh, LD; See, RE | 1 |
| Bailie, TM; Li, N; Sanchez, CJ; Sorg, BA; Wu, WR | 1 |
| Baker, DA; Kalivas, PW; Lake, RW; McFarland, K; Shen, H; Tang, XC; Toda, S | 1 |
| Fabbricatore, AT; Ghitza, UE; Pawlak, AP; Prokopenko, V; West, MO | 1 |
| Camí, J; Farré, M | 1 |
| Davidge, SB; Kalivas, PW; Lapish, CC; McFarland, K | 1 |
| Ho, A; Kreek, MJ; Mantsch, JR; Mathieu-Kia, AM; Yuferov, V | 1 |
| Boilet, V; Cador, M; Dias, C; Huitelec, E; Lachize, S | 1 |
| Dempsey, J; Lu, L | 1 |
| Dempsey, J; Grimm, JW; Lu, L; Shaham, Y | 1 |
| Evans, KA; Fuchs, RA; Parker, MC; See, RE | 1 |
| Evans, KA; Fuchs, RA; Parker, MP; See, RE | 1 |
| Carter, L; Hall, W | 1 |
| Beardsley, PM; Hendrick, E; Shelton, KL | 1 |
| Faccidomo, S; Kikusui, T; Miczek, KA | 1 |
| Ashby, CR; Gardner, EL; Gilbert, JG; Heidbreder, CA; Newman, AH; Pak, AC; Peng, XQ; Xi, ZX | 1 |
| Kosten, TA; Zhang, XY | 1 |
| Bimonte-Nelson, HA; Case, JM; Fuchs, RA; Kippin, TE; Mehta, RH; Parker, MP; See, RE | 1 |
| Erb, S; Fletcher, PJ; Placenza, FM; Vaccarino, FJ | 1 |
| See, RE | 1 |
| Anderson, SM; Famous, KR; Kumaresan, V; Pierce, RC; Schmidt, HD | 1 |
| Rebec, GV; Sun, W | 1 |
| Erb, S; Kayyali, H; Petrovic, A; Yi, D | 1 |
| Gardner, EL; Gilbert, JG; Li, X; Pak, AC; Peng, XQ; Xi, ZX | 1 |
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| Awad, S; Baker, DA; Katz, E; Li, SJ; Mantsch, JR; Risinger, R; Yang, Z | 1 |
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| Akhavan, A; Festa, ED; Jenab, S; Luine, V; Minerly, AC; Nazarian, A; Niyomchai, T; Quiñones-Jenab, V; Russo, SJ; Sun, WL; Weierstall, K | 1 |
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| Deroche, V; Jodogne, C; Le Moal, M; Maccari, S; Marinelli, M; Piazza, PV; Rougé-Pont, F; Simon, H | 1 |
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| Ahn, C; Comings, DE; Flanagan, SD; Gysin, R; Muhleman, D | 1 |
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| Alterman, AI; August, DS; Cornish, JW; Droba, M; Hall, CP; McLellan, AT; O'Brien, CP; Raphaelson, AH; Schrade, FX; Snider, EC | 1 |
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| Hall, SM; Havassy, BE; Wasserman, DA | 2 |
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| Alterman, AI; Cacciola, JS; McKay, JR; Rutherford, MJ | 1 |
| Cervo, L; Samanin, R | 1 |
| Alterman, AI; Cacciola, JS; Kabasakalian-McKay, R; McKay, JR; Rutherford, MJ | 1 |
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| Alterman, AI; Cacciola, JS; Koppenhaver, J; McKay, JR; O'Brien, CP; Rutherford, MJ | 1 |
| Cornish, J; Kalivas, PW; Pierce, RC; Sorg, BA | 1 |
| Adelekan, ML; Lawal, RA; Ohaeri, JU; Orija, OB | 1 |
| Erb, S; Shaham, Y; Stewart, J | 1 |
| Anson, A; Chasnoff, IJ; Hatcher, R; Iaukea, K; Randolph, LA; Stenson, H | 1 |
| Coppola, R; Doty, L; Geyer, C; Gorey, JG; Heinz, A; Hommer, D; Jones, DW; Knable, MB; Lee, KS; Linnoila, M; Ragan, P; Weinberger, DR; Williams, W | 1 |
| Cornish, JL; Duffy, P; Kalivas, PW | 1 |
| Barrett-Larimore, RL; Khroyan, TV; Platt, DM; Rowlett, JK; Spealman, RD | 1 |
| Carroll, ME; Lynch, WJ | 1 |
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| Ashley, JA; Carrera, MR; Janda, KD; Koob, GF; Wirsching, P; Zhou, B | 1 |
| Bailey, R; Creson, D; Grabowski, J; Rhoades, H; Schmitz, JM; Silverman, P; Stotts, A | 1 |
| Innis, RB; Jacobsen, LK; Kosten, TR; Malison, RT; Seibyl, JP; Staley, JK; Zoghbi, SS | 1 |
| Cornish, JL; Kalivas, PW | 1 |
| Gardner, EL; Hayes, RJ; Liu, X; Spector, JA; Vorel, SR | 1 |
| Grimm, JW; Kruzich, PJ; See, RE | 1 |
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| Angeletti, S; Ben-Shahar, O; Ciccocioppo, R; Katner, S; Liu, X; Parsons, LH; Richter, RR; Valdez, GR; Weiss, F; Zorrilla, EP | 1 |
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| Crombag, H; De Vries, TJ; Dieben, J; Homberg, JR; Schoffelmeer, AN; Schuurman, K; Shaham, Y; Vanderschuren, LJ | 1 |
| Kalivas, PW; McFarland, K | 1 |
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| Grimm, JW; Shaham, Y; Shalev, U | 1 |
| Anderson, SM; Bari, AA; Jey, AR; Park, WK; Pierce, RC; Rowlett, JK; Spealman, RD | 1 |
| Deroche-Gamonet, V; Le Moal, M; Piat, F; Piazza, PV | 1 |
| Flores, J; Leri, F; Rodaros, D; Stewart, J | 1 |
| Kopanda, RT; Post, RM | 1 |
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| Frawley, PJ; Smith, JW | 1 |
| Childress, AR; Ehrman, R; McLellan, AT; O'Brien, CP | 2 |
| Brogan, WC; Glamann, DB; Hillis, LD; Lange, RA | 1 |
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| Berry, E; Christensen, C; Dembo, R; Genung, L; Getreu, A; Schmeidler, J; Williams, L; Wish, ED | 1 |
| Kilaru, P; Kim, W; Sequeira, W | 1 |
| Ling, W; McCann, MJ; Obert, JL; Rawson, RA | 1 |
| Hall, SM; Havassy, BE; Wasserman, DM | 1 |
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| Carroll, KM; Keller, DS; Rounsaville, BJ | 1 |
| O'Neil, J; Wish, ED | 1 |
| Barrett, O; Bennett, RL; Horst, E | 1 |
| Dellinger, RP; Majid, PA; Zimmerman, JL | 1 |
| Leibovitch, ER; O'Halloran, RL; Prichard, JG | 1 |
| Brown, SB; Condon, CM; Horger, EO | 1 |
| Childress, AR; Ehrman, R; McLellan, T; O'Brien, CP | 1 |
| McAfee, B; McElroy, S; Mello, NK; Mendelson, JH; Teoh, SK; Weiss, R | 1 |
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| Bauer, L; Kranzler, H | 1 |
| McAfee, B; McElroy, SL; Mello, NK; Mendelson, JH; Teoh, SK; Weiss, RD | 1 |
| Godwin, JE; Harley, RA; Heffner, JE; Hefner, JE; Miller, KS | 1 |
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| Gustafson, GM; Kemp, HG; Zimmerman, FH | 1 |
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| Gold, MS; Pottash, AC; Washton, AM | 1 |
| Gawin, F; Kleber, H; Rounsaville, BJ | 1 |
| Ballantyne, J | 1 |
| Sells, SB; Simpson, DD | 1 |
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| Franken, IHA; Remmerswaal, D; Shahbabaie, A; van der Veen, FM; Verveer, I | 1 |
| Nappo, SA; Silva, TRD | 1 |
| Gillis, JA; Green, P; Williams, J | 1 |
| Baker, J; Burgos, M; Handal, AJ; Hunley, K; Long, J; Rendón, A; Rosas-Taraco, A; Young, BN | 1 |
| Blanken, P; Da Silveira, D; Fischer, B; Gallassi, A; Goldner, EM; Rehm, J; Tyndall, M; Wood, E | 1 |
| Booth, BM; Carlson, RG; Falck, R; Garrity, TF; Leukefeld, CG; Oser, CB; Tindall, MS; Wang, J | 1 |
| Abdallah, AB; Bradford, S; Cottler, LB; Johnson, JE; O'Leary, CC; Striley, CW | 1 |
| Grenier, N; Reutemann, P; Telang, GH | 1 |
| Crowley, EM; Foltz, C; Kissin, W; Leahy, PJ; McKay, JR; Stephens, RC | 1 |
| Carter, TB; Dansby, LM; Diskin, CJ; Radcliff, L; Stokes, TJ | 1 |
| Cornut, P; Gilbert, O; Hanquet, O; Lardinois, I; Mathieu, D; Pierard, P; Van Meerhaeghe, A | 1 |
| Bucciarelli, A; Coffin, PO; Galea, S; Ompad, D; Tracy, M; Vlahov, D | 1 |
| Barquist, ES; Feuer, WJ; Schuster, KM | 1 |
| Blaho, K; Geraci, S; Logan, B; Winbery, S | 1 |
| Gorman, M; Snow, D | 1 |
| Gossop, M; Kidd, T; Marsden, J; Stewart, D | 1 |
| Ogunmakin, K; Raji, K; Ranario, J | 1 |
| Binzak, JM; Kelley, AE; Schroeder, BE | 1 |
| Cho, KS; Chung, BH; Hong, CH; Koo, KC; Lee, KS; Lee, SH | 1 |
| Jordan, DR; Valberg, JD | 1 |
28 review(s) available for cocaine and Recrudescence
| Article | Year |
|---|---|
Sex Differences in Opioid and Psychostimulant Craving and Relapse: A Critical Review.
Topics: Analgesics, Opioid; Animals; Cocaine; Cocaine-Related Disorders; Craving; Extinction, Psychological; Female; Humans; Male; Recurrence; Self Administration; Sex Characteristics | 2022 |
Preventing incubation of drug craving to treat drug relapse: from bench to bedside.
Topics: Animals; Cocaine; Craving; Cues; Drug-Seeking Behavior; Pharmaceutical Preparations; Recurrence; Self Administration; Substance-Related Disorders | 2023 |
Endocannabinoid system as a therapeutic target for psychostimulants relapse: A systematic review of preclinical studies.
Topics: Amphetamine; Animals; Cannabinoid Receptor Antagonists; Central Nervous System Stimulants; Cocaine; Endocannabinoids; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Receptors, Cannabinoid; Recurrence | 2023 |
Epigenetic Mechanisms in Drug Relapse.
Topics: Cocaine; Conditioning, Operant; Cues; Drug-Seeking Behavior; Epigenesis, Genetic; Extinction, Psychological; Humans; Pharmaceutical Preparations; Recurrence; Self Administration | 2021 |
Voluntary exercise as a treatment for incubated and expanded drug craving leading to relapse to addiction: Animal models.
Topics: Animals; Behavior, Addictive; Cocaine; Craving; Drug-Seeking Behavior; Exercise Therapy; Female; Heroin; Humans; Male; Methamphetamine; Models, Animal; Physical Conditioning, Animal; Rats; Recurrence; Self Administration; Substance-Related Disorders | 2021 |
Extinction vs. Abstinence: A Review of the Molecular and Circuit Consequences of Different Post-Cocaine Experiences.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Extinction, Psychological; Humans; Nerve Net; Recurrence | 2021 |
Modeling cocaine relapse in rodents: Behavioral considerations and circuit mechanisms.
Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Drug-Seeking Behavior; Extinction, Psychological; Humans; Neural Pathways; Recurrence; Rodentia; Self Administration | 2018 |
Bipolar disorder and substance misuse: pathological and therapeutic implications of their comorbidity and cross-sensitisation.
Topics: Acetylcysteine; Age of Onset; Animals; Basal Ganglia; Behavior, Addictive; Bipolar Disorder; Brain-Derived Neurotrophic Factor; Central Nervous System Sensitization; Cocaine; Cocaine-Related Disorders; Comorbidity; Diagnosis, Dual (Psychiatry); Disease Models, Animal; Disease Progression; Dopamine Uptake Inhibitors; Epigenomics; Free Radical Scavengers; Humans; Recurrence; Stress, Psychological | 2013 |
COKE LIVe: recurrent vasculitis secondary to cocaine contaminated with levamisole.
Topics: Adult; Cocaine; Cocaine-Related Disorders; Drug Contamination; Female; Humans; Ireland; Levamisole; Male; Recurrence; Risk Assessment; Vasculitis | 2016 |
Review. Context-induced relapse to drug seeking: a review.
Topics: Animals; Behavior, Addictive; Brain; Cocaine; Conditioning, Psychological; Ethanol; Extinction, Psychological; Heroin; Humans; Neurotransmitter Agents; Nicotine; Rats; Recurrence; Self Administration; Substance-Related Disorders | 2008 |
Glutamate and reinstatement.
Topics: Animals; Behavior, Addictive; Brain; Cocaine; Ethanol; Glutamic Acid; Heroin; Humans; Nicotine; Receptors, Glutamate; Recurrence; Substance-Related Disorders; Synaptic Transmission | 2009 |
Alcoholics anonymous effectiveness: faith meets science.
Topics: Alcoholics Anonymous; Cocaine; Humans; Narcotics; Patient Compliance; Randomized Controlled Trials as Topic; Recurrence; Substance-Related Disorders; Treatment Outcome | 2009 |
Evaluation of the relationship between anxiety during withdrawal and stress-induced reinstatement of cocaine seeking.
Topics: Animals; Anxiety; Brain; Cocaine; Cocaine-Related Disorders; Corticotropin-Releasing Hormone; Dopamine; Humans; Norepinephrine; Rats; Recurrence; Self Administration; Stress, Psychological; Substance Withdrawal Syndrome | 2010 |
[Genetic study on schizophrenia and its recurrence utilizing pharmacological models].
Topics: Amphetamine; Animals; Central Nervous System Stimulants; Cocaine; Disease Models, Animal; Dopamine Agents; Humans; Ketamine; Phencyclidine; Receptors, N-Methyl-D-Aspartate; Recurrence; Schizophrenia | 2002 |
Drug addiction.
Topics: Animals; Cannabinoids; Cocaine; Disease Models, Animal; Dopamine; Ethanol; Humans; Narcotics; Nicotine; Recurrence; Reinforcement, Psychology; Substance Withdrawal Syndrome; Substance-Related Disorders | 2003 |
Neural substrates of cocaine-cue associations that trigger relapse.
Topics: Amygdala; Animals; Association Learning; Brain; Cocaine; Conditioning, Operant; Cues; Recurrence; Substance-Related Disorders | 2005 |
Anatomy and pharmacology of cocaine priming-induced reinstatement of drug seeking.
Topics: Basal Ganglia; Cocaine; Cocaine-Related Disorders; Dopamine; Glutamic Acid; Humans; Limbic System; Models, Neurological; Neural Pathways; Recurrence; Synaptic Transmission | 2005 |
Cardiovascular manifestations of cocaine abuse. A case of recurrent dilated cardiomyopathy.
Topics: Arrhythmias, Cardiac; Cardiomyopathy, Dilated; Chest Pain; Cocaine; Humans; Male; Middle Aged; Myocardial Ischemia; Recurrence; Substance-Related Disorders | 1994 |
The treatment of stimulant dependence.
Topics: Amphetamines; Central Nervous System Stimulants; Cocaine; Combined Modality Therapy; Humans; Recurrence; Substance-Related Disorders | 1994 |
Relapse to cocaine use: conceptual issues.
Topics: Cocaine; Cues; Female; Humans; Male; Recurrence; Sex Factors; Social Support; Substance-Related Disorders | 1993 |
Pharmacological and environmental determinants of relapse to cocaine-seeking behavior.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Humans; Rats; Recurrence; Social Environment | 1999 |
Compulsive drug-seeking behavior and relapse. Neuroadaptation, stress, and conditioning factors.
Topics: Adaptation, Physiological; Affect; Animals; Central Nervous System Depressants; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Disease Models, Animal; Dopamine Uptake Inhibitors; Ethanol; Humans; Nucleus Accumbens; Receptors, Dopamine; Receptors, Serotonin; Recurrence; Reinforcement, Psychology; Stress, Psychological; Substance Withdrawal Syndrome; Substance-Related Disorders | 2001 |
Neurobiology of relapse to heroin and cocaine seeking: a review.
Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Cues; Extinction, Psychological; Heroin; Heroin Dependence; Rats; Recurrence; Self Administration; Stress, Psychological | 2002 |
Cocaine, kindling, and psychosis.
Topics: Amphetamine; Cocaine; Drug Tolerance; Electric Stimulation; Epilepsy, Temporal Lobe; Humans; Lidocaine; Limbic System; Models, Biological; Models, Neurological; Neurocognitive Disorders; Psychoses, Substance-Induced; Recurrence; Seizures; Stress, Psychological | 1976 |
Structural anomalies resulting from vascular disruption.
Topics: Abnormalities, Drug-Induced; Blood Vessels; Cocaine; Congenital Abnormalities; Constriction, Pathologic; Humans; Recurrence | 1992 |
Pharmacotherapeutic interventions for cocaine abuse: present practices and future directions.
Topics: Antipsychotic Agents; Benzodiazepines; Carbamazepine; Cocaine; Dopamine Agents; Humans; Recurrence; Serotonin Antagonists; Substance Withdrawal Syndrome; Substance-Related Disorders | 1991 |
Effectiveness of secondary prevention and treatment interventions for crack-cocaine abuse: a comprehensive narrative overview of English-language studies.
Topics: Behavior, Addictive; Central Nervous System Stimulants; Cocaine-Related Disorders; Crack Cocaine; Drug Users; Health Behavior; Health Knowledge, Attitudes, Practice; Health Services Accessibility; Humans; Recurrence; Risk Factors; Secondary Prevention; Substance Abuse Treatment Centers; Treatment Outcome | 2015 |
Goodness, gracious, great balls of fire: A case of transient lingual papillitis following consumption of an Atomic Fireball.
Topics: Adult; Candy; Female; Glossitis; Humans; Recurrence | 2016 |
24 trial(s) available for cocaine and Recrudescence
| Article | Year |
|---|---|
Targeting white matter neuroprotection as a relapse prevention strategy for treatment of cocaine use disorder: Design of a mechanism-focused randomized clinical trial.
Topics: Animals; Cocaine; Humans; Neuroprotection; Recurrence; Secondary Prevention; White Matter | 2021 |
Cannabidiol as a treatment for craving and relapse in individuals with cocaine use disorder: a randomized placebo-controlled trial.
Topics: Adult; Bayes Theorem; Cannabidiol; Cocaine; Craving; Female; Humans; Recurrence | 2021 |
Impact of endogenous progesterone on reactivity to yohimbine and cocaine cues in cocaine-dependent women.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adult; Anxiety; Cocaine; Cocaine-Related Disorders; Craving; Cues; Double-Blind Method; Drug-Seeking Behavior; Female; Humans; Middle Aged; Placebos; Progesterone; Recurrence; Stress, Psychological; Yohimbine | 2018 |
Prospective associations between brain activation to cocaine and no-go cues and cocaine relapse.
Topics: Adult; Behavior, Addictive; Brain; Cocaine; Cues; Female; Follow-Up Studies; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Photic Stimulation; Prospective Studies; Psychomotor Performance; Recurrence | 2013 |
Who benefits from extended continuing care for cocaine dependence?
Topics: Adult; Ambulatory Care; Cocaine; Cocaine-Related Disorders; Counseling; Female; Humans; Long-Term Care; Male; Middle Aged; Motivation; Patient Compliance; Psychotherapy, Group; Recurrence; Substance Abuse Detection; Telephone; Treatment Outcome | 2014 |
Cocaine abuse versus cocaine dependence: cocaine self-administration and pharmacodynamic response in the human laboratory.
Topics: Adult; Blood Pressure; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Double-Blind Method; Electrocardiography; Exploratory Behavior; Female; Heart Rate; Humans; Impulsive Behavior; Male; Middle Aged; Patient Selection; Psychiatric Status Rating Scales; Recurrence; Reinforcement Schedule; Safety; Self Administration; Skin Temperature; Substance Abuse, Intravenous | 2010 |
Acoustic startle reduction in cocaine dependence persists for 1 year of abstinence.
Topics: Acoustic Stimulation; Blinking; Cocaine; Cocaine-Related Disorders; Electromyography; Female; Humans; Male; Middle Aged; Reaction Time; Recurrence; Sensory Gating; Substance Withdrawal Syndrome | 2011 |
Heroin and cocaine craving and use during treatment: measurement validation and potential relationships.
Topics: Adult; Ambulatory Care; Cocaine; Cocaine-Related Disorders; Female; Heroin; Heroin Dependence; Humans; Male; Middle Aged; Motivation; Pain Measurement; Patient Dropouts; Personality Inventory; Psychometrics; Recurrence; Reproducibility of Results; Self Efficacy; Statistics as Topic; Substance Abuse Detection; Substance Withdrawal Syndrome; Surveys and Questionnaires; Treatment Refusal | 2006 |
Tryptophan depletion and attenuation of cue-induced craving for cocaine.
Topics: Adult; Amino Acids; Cocaine; Cues; Double-Blind Method; Drinking; Habituation, Psychophysiologic; Hospitalization; Humans; Male; Middle Aged; Placebos; Racial Groups; Recurrence; Serotonin; Substance Abuse, Intravenous; Substance-Related Disorders; Treatment Outcome; Tryptophan | 1995 |
One-year follow-up of psychotherapy and pharmacotherapy for cocaine dependence. Delayed emergence of psychotherapy effects.
Topics: Adaptation, Psychological; Adult; Ambulatory Care; Behavior Therapy; Cocaine; Cognitive Behavioral Therapy; Desipramine; Double-Blind Method; Female; Follow-Up Studies; Humans; Male; Placebos; Psychotherapy, Brief; Recurrence; Substance-Related Disorders; Treatment Outcome | 1994 |
Effectiveness and costs of inpatient versus day hospital cocaine rehabilitation.
Topics: Adult; Aftercare; Cocaine; Costs and Cost Analysis; Day Care, Medical; Female; Follow-Up Studies; Health Status Indicators; Hospitalization; Humans; Male; Middle Aged; Recurrence; Social Adjustment; Substance Abuse Detection; Substance Abuse Treatment Centers; Substance-Related Disorders; Treatment Outcome | 1994 |
Outpatient treatment for cocaine abuse: a controlled comparison of relapse prevention and twelve-step approaches.
Topics: Adult; Aftercare; Alcoholism; Ambulatory Care; Cocaine; Cognitive Behavioral Therapy; Female; Follow-Up Studies; Humans; Male; Marijuana Abuse; Middle Aged; Recurrence; Self-Help Groups; Substance Abuse Detection; Substance-Related Disorders; Treatment Outcome | 1994 |
Mazindol for relapse prevention to cocaine abuse in methadone-maintained patients.
Topics: Adult; Cocaine; Combined Modality Therapy; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Mazindol; Methadone; Narcotic Antagonists; Psychotherapy; Recurrence; Substance-Related Disorders | 1995 |
Selective sensitization to the psychosis-inducing effects of cocaine: a possible marker for addiction relapse vulnerability?
Topics: Adult; Biomarkers; Cocaine; Crack Cocaine; Female; Humans; Male; Narcotics; Opioid-Related Disorders; Paranoid Disorders; Psychoses, Substance-Induced; Recurrence | 1997 |
Comparing self-reported cocaine use with repeated urine tests in outpatient cocaine abusers.
Topics: Adult; Cocaine; Fluorescence Polarization Immunoassay; Humans; Male; Outpatients; Patient Compliance; Recurrence; Substance Abuse Detection; Substance-Related Disorders | 1997 |
Group counseling versus individualized relapse prevention aftercare following intensive outpatient treatment for cocaine dependence: initial results.
Topics: Adult; Aftercare; Ambulatory Care; Cocaine; Cognitive Behavioral Therapy; Follow-Up Studies; Humans; Male; Middle Aged; Psychotherapy, Group; Recurrence; Substance-Related Disorders; Treatment Outcome; Veterans | 1997 |
Risperidone for the treatment of cocaine dependence: randomized, double-blind trial.
Topics: Adult; Cocaine; Cocaine-Related Disorders; Dopamine Antagonists; Double-Blind Method; Female; Humans; Male; Patient Dropouts; Psychotherapy; Recurrence; Risperidone; Time Factors | 2000 |
Recurrent coronary vasoconstriction caused by intranasal cocaine: possible role for metabolites.
Topics: Administration, Intranasal; Adult; Aged; Cineangiography; Cocaine; Coronary Angiography; Coronary Vessels; Double-Blind Method; Female; Humans; Male; Middle Aged; Random Allocation; Recurrence; Vasoconstriction | 1992 |
A comparative trial of psychotherapies for ambulatory cocaine abusers: relapse prevention and interpersonal psychotherapy.
Topics: Adolescent; Adult; Ambulatory Care; Cocaine; Combined Modality Therapy; Female; Humans; Male; Patient Dropouts; Personality Assessment; Psychotherapy; Recurrence; Substance-Related Disorders | 1991 |
Integrating systemic cue exposure with standard treatment in recovering drug dependent patients.
Topics: Adult; Arousal; Behavior Therapy; Cocaine; Combined Modality Therapy; Conditioning, Classical; Cues; Extinction, Psychological; Follow-Up Studies; Humans; Pilot Projects; Recurrence; Substance-Related Disorders | 1990 |
Hyperprolactinemia and risk for relapse of cocaine abuse.
Topics: Adult; Cocaine; Desipramine; Double-Blind Method; Female; Humans; Hyperprolactinemia; Male; Prolactin; Radioimmunoassay; Recurrence; Substance-Related Disorders | 1990 |
Desipramine treatment for relapse prevention in cocaine dependence.
Topics: Adult; Cocaine; Desipramine; Double-Blind Method; Female; Humans; Length of Stay; Male; Personality Tests; Pilot Projects; Randomized Controlled Trials as Topic; Recurrence; Substance-Related Disorders | 1989 |
Multi-session electrical neuromodulation effects on craving, relapse and cognitive functions in cocaine use disorder: A randomized, sham-controlled tDCS study.
Topics: Adult; Chronic Disease; Cocaine-Related Disorders; Cognition; Crack Cocaine; Craving; Double-Blind Method; Female; Gambling; Humans; Male; Middle Aged; Prefrontal Cortex; Recurrence; Research Design; Transcranial Direct Current Stimulation | 2020 |
Effects of major depression on crack use and arrests among women in drug court.
Topics: Adolescent; Adult; Black or African American; Cocaine-Related Disorders; Crack Cocaine; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Female; Humans; Law Enforcement; Patient Dropouts; Recurrence; Regression Analysis; Risk Factors; United States | 2011 |
342 other study(ies) available for cocaine and Recrudescence
| Article | Year |
|---|---|
CB1 receptor antagonist AM4113 reverts the effects of cannabidiol on cue and stress-induced reinstatement of cocaine-seeking behaviour in mice.
Topics: Animals; Behavior, Addictive; Behavior, Animal; Cannabidiol; Cocaine; Cues; Drug-Seeking Behavior; Extinction, Psychological; Humans; Male; Mice; Prefrontal Cortex; Pyrazoles; Receptor, Cannabinoid, CB1; Recurrence; Self Administration; Ventral Striatum | 2022 |
Changes in Drug-Related Implicit Associations during Substance Use Disorder Treatment: The Role of the Therapeutic Context.
Topics: Cocaine; Cognition; Humans; Memory; Recurrence; Substance-Related Disorders | 2022 |
Negative Urgency Exacerbates Relapse to Cocaine Seeking After Abstinence.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Cues; Drug-Seeking Behavior; Male; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration | 2022 |
Investigating individual differences in opioid-taking and opioid-seeking behavior in male rats.
Topics: Analgesics, Opioid; Animals; Cocaine; Cocaine-Related Disorders; Cues; Drug-Seeking Behavior; Extinction, Psychological; Individuality; Male; Rats; Rats, Sprague-Dawley; Recurrence; Remifentanil; Self Administration | 2022 |
Increased heroin intake and relapse vulnerability in intermittent relative to continuous self-administration: Sex differences in rats.
Topics: Animals; Cocaine; Extinction, Psychological; Female; Heroin; Male; Rats; Recurrence; Self Administration; Sex Characteristics | 2023 |
Contextual extinction of drug-associated discriminative stimuli fails to attenuate drug-vs-food choice in rhesus monkeys.
Topics: Animals; Cocaine; Dose-Response Relationship, Drug; Female; Heroin; Macaca mulatta; Male; Pharmaceutical Preparations; Recurrence | 2022 |
Ulotaront, a novel TAAR1 agonist with 5-HT1A agonist activity, lacks abuse liability and attenuates cocaine cue-induced relapse in rats.
Topics: Animals; Cocaine; Cues; Dose-Response Relationship, Drug; Extinction, Psychological; Female; Male; Rats; Receptors, G-Protein-Coupled; Recurrence; Self Administration; Serotonin 5-HT1 Receptor Agonists | 2022 |
TAAR1 regulates drug-induced reinstatement of cocaine-seeking via negatively modulating CaMKIIα activity in the NAc.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Drug-Seeking Behavior; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Recurrence; Self Administration | 2022 |
Activation of mesocorticolimbic dopamine projections initiates cue-induced reinstatement of reward seeking in mice.
Topics: Animals; Cocaine; Cues; Dopamine; Drug-Seeking Behavior; Mice; Mice, Transgenic; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Recurrence; Reward; Self Administration | 2022 |
A Procedure to Study Stress-induced Relapse of Heroin Seeking after Punishment-imposed Abstinence.
Topics: Animals; Cocaine; Extinction, Psychological; Heroin; Heroin Dependence; Punishment; Rats; Recurrence; Self Administration | 2022 |
Rapid Eye Movement Sleep Engages Melanin-Concentrating Hormone Neurons to Reduce Cocaine Seeking.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Male; Neurons; Nucleus Accumbens; Rats; Recurrence; Self Administration; Sleep; Sleep, REM; Substance Withdrawal Syndrome | 2022 |
Investigating discriminative stimulus modulation of opioid seeking after conflict-induced abstinence in sign- and goal-tracking rats.
Topics: Analgesics, Opioid; Animals; Cocaine; Female; Fentanyl; Goals; Male; Polyesters; Rats; Rats, Sprague-Dawley; Recurrence | 2022 |
Hierarchical cue control of cocaine seeking in the face of cost.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Cues; Drug-Seeking Behavior; Extinction, Psychological; Female; Humans; Male; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration | 2023 |
Endocannabinoids regulate cocaine-associated memory through brain AEA-CB1R signalling activation.
Topics: Brain; Cannabinoids; Cocaine; Endocannabinoids; Humans; Ligands; Lipase; Receptors, Cannabinoid; Recurrence | 2022 |
Sex-dependent effects of chronic stress on punished cocaine self-administration and cue-induced relapse to cocaine seeking.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Cues; Drug-Seeking Behavior; Extinction, Psychological; Female; Humans; Male; Rats; Recurrence; Self Administration | 2022 |
Individual differences in cocaine seeking during voluntary abstinence predicts cocaine relapse and the circuitry mediating relapse.
Topics: Animals; Ceftriaxone; Cocaine; Cocaine-Related Disorders; Cues; Extinction, Psychological; Individuality; Male; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration; Sucrose | 2022 |
Cell type and sex specific insights into ventral striatum deep brain stimulation for cocaine relapse.
Topics: Cocaine; Corpus Striatum; Deep Brain Stimulation; Dopamine Uptake Inhibitors; Female; Humans; Male; Recurrence; Ventral Striatum | 2023 |
Context-drug-associations and reinstatement of drug-seeking behavior in male rats: Adolescent and adult time-dependent effects.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Drug-Seeking Behavior; Extinction, Psychological; Male; Pharmaceutical Preparations; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration | 2023 |
Increased Excitability and Synaptic Plasticity of Drd1- and Drd2-Expressing Prelimbic Neurons Projecting to Nucleus Accumbens after Heroin Abstinence Are Reversed by Cue-Induced Relapse and Protein Kinase A Inhibition.
Topics: Animals; Cocaine; Cues; Cyclic AMP-Dependent Protein Kinases; Heroin; Male; Neuronal Plasticity; Neurons; Nucleus Accumbens; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Receptors, Dopamine D2; Recurrence | 2023 |
A multivariate regressor of patterned dopamine release predicts relapse to cocaine.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Dopamine; Extinction, Psychological; Male; Mice; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Recurrence | 2023 |
Increased Excitability of Layer 2 Cortical Pyramidal Neurons in the Supplementary Motor Cortex Underlies High Cocaine-Seeking Behaviors.
Topics: Animals; Cocaine; Drug-Seeking Behavior; Motor Cortex; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration | 2023 |
Operant novelty seeking predicts cue-induced reinstatement following cocaine but not water reinforcement in male rats.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Exploratory Behavior; Extinction, Psychological; Male; Rats; Recurrence; Self Administration | 2023 |
A visual circuit related to the habenula mediates the prevention of cocaine relapse by bright light treatment.
Topics: Cocaine; Habenula; Humans; Neurons; Recurrence; Thalamus | 2023 |
Activation of Epac in the BLA disrupts reconsolidation and attenuates heroin-seeking behaviour.
Topics: Amygdala; Animals; Cocaine; Cues; Extinction, Psychological; Heroin; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration | 2023 |
Exploring the Bridge From Extracellular Signals to Intracellular Plasticity.
Topics: Cocaine; Cues; Extracellular Matrix; Humans; Integrin beta3; Neuronal Plasticity; Recurrence | 2019 |
The cognitive cost of reducing relapse to cocaine-seeking with mGlu5 allosteric modulators.
Topics: Animals; Benzamides; Cocaine; Cognition; Cues; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Excitatory Amino Acid Antagonists; Male; Memory, Short-Term; Pyrazoles; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Recurrence; Self Administration; Thiazoles | 2020 |
Ventral pallidum is essential for cocaine relapse after voluntary abstinence in rats.
Topics: Animals; Basal Forebrain; Cocaine; Conditioning, Operant; Drug-Seeking Behavior; Female; Male; Punishment; Rats, Long-Evans; Recurrence | 2019 |
Anti-relapse neurons in the infralimbic cortex of rats drive relapse-suppression by drug omission cues.
Topics: Alcoholism; Animals; Cocaine; Compulsive Behavior; Conditioning, Operant; Cues; Dopamine Uptake Inhibitors; Male; Neurons; Prefrontal Cortex; Rats, Long-Evans; Rats, Sprague-Dawley; Rats, Transgenic; Recurrence; Substance-Related Disorders | 2019 |
Ventral pallidum: a promising target for addiction intervention.
Topics: Animals; Basal Forebrain; Behavior, Addictive; Cocaine; Globus Pallidus; Rats; Recurrence | 2019 |
Administration of a novel high affinity PICK1 PDZ domain inhibitor attenuates cocaine seeking in rats.
Topics: Animals; Animals, Newborn; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Corpus Striatum; Cytoskeletal Proteins; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Male; Motor Activity; Neurons; Nucleus Accumbens; PDZ Domains; Rats; Rats, Sprague-Dawley; Recurrence | 2020 |
The effects of nicotinamide on reinstatement to cocaine seeking in male and female Sprague Dawley rats.
Topics: Animals; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Cues; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Extinction, Psychological; Female; Male; Niacinamide; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration; Vitamin B Complex | 2020 |
Effects of Cocaine Exposure on Astrocytic Glutamate Transporters and Relapse-Like Ethanol-Drinking Behavior in Male Alcohol-Preferring Rats.
Topics: Alcohol Drinking; Amino Acid Transport System X-AG; Animals; Astrocytes; Blotting, Western; Brain; Cocaine; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Male; Rats; Recurrence | 2020 |
Facilitative effects of environmental enrichment for cocaine relapse prevention are dependent on extinction training context and involve increased TrkB signaling in dorsal hippocampus and ventromedial prefrontal cortex.
Topics: Animals; Behavior, Addictive; Brain; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Dopamine Uptake Inhibitors; Extinction, Psychological; Hippocampus; Male; Memory; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Wistar; Receptor, trkB; Recurrence; Secondary Prevention; Self Administration | 2020 |
Role of adolescent-formed, context-drug-associations on reinstatement of drug-seeking behavior in rats.
Topics: Age Factors; Animals; Cocaine; Cocaine-Related Disorders; Cues; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Extinction, Psychological; Male; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration; Social Isolation | 2020 |
The anterior insular cortex in the rat exerts an inhibitory influence over the loss of control of heroin intake and subsequent propensity to relapse.
Topics: Animals; Cerebral Cortex; Cocaine; Extinction, Psychological; Heroin; Rats; Recurrence; Self Administration | 2020 |
Alterations in nicotinic receptor alpha5 subunit gene differentially impact early and later stages of cocaine addiction: a translational study in transgenic rats and patients.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Humans; Rats; Rats, Transgenic; Receptors, Nicotinic; Recurrence | 2021 |
(±)VK4-40, a novel dopamine D
Topics: Animals; Cocaine; Cocaine-Related Disorders; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Mice; Pharmaceutical Preparations; Rats; Rats, Long-Evans; Receptors, Dopamine D3; Recurrence; Reward; Rodentia; Self Administration | 2020 |
Neuroadaptations in the dorsal hippocampus underlie cocaine seeking during prolonged abstinence.
Topics: Activins; Animals; Cocaine; Cocaine-Related Disorders; Drug-Seeking Behavior; Extinction, Psychological; Hippocampus; Inhibin-beta Subunits; Male; Neuronal Plasticity; Phosphorylation; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration; Transforming Growth Factor beta | 2020 |
Hippocampal plasticity may drive cocaine relapse.
Topics: Cocaine; Dopamine Uptake Inhibitors; Hippocampus; Humans; Recurrence | 2020 |
Profiles of patients with cocaine and alcohol use disorder based on cognitive domains and their relationship with relapse.
Topics: Adult; Alcoholism; Behavior, Addictive; Chronic Disease; Cocaine; Cocaine-Related Disorders; Cognition; Emotions; Female; Humans; Impulsive Behavior; Male; Middle Aged; Recurrence | 2021 |
Restoring glutamate homeostasis in the nucleus accumbens via endocannabinoid-mimetic drug prevents relapse to cocaine seeking behavior in rats.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Endocannabinoids; Extinction, Psychological; Glutamic Acid; Homeostasis; Nucleus Accumbens; Pharmaceutical Preparations; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration | 2021 |
5-HT
Topics: Animals; Cocaine; Cocaine-Related Disorders; Cues; Female; Locomotion; Male; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Recurrence; Reinforcement, Psychology; Self Administration; Serotonin 5-HT1 Receptor Agonists; Time Factors | 2021 |
Inactivation of the infralimbic cortex decreases discriminative stimulus-controlled relapse to cocaine seeking in rats.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Cues; Drug-Seeking Behavior; Extinction, Psychological; Prefrontal Cortex; Rats; Recurrence; Self Administration | 2021 |
The protective effect of operant social reward on cocaine self-administration, choice, and relapse is dependent on delay and effort for the social reward.
Topics: Animals; Cocaine; Conditioning, Operant; Female; Male; Rats; Rats, Sprague-Dawley; Recurrence; Reward; Self Administration | 2021 |
Relapse to cocaine seeking in an invertebrate.
Topics: Animals; Behavior, Addictive; Cocaine; Conditioning, Operant; Drug-Seeking Behavior; Extinction, Psychological; Invertebrates; Locomotion; Planarians; Recurrence; Reinforcement, Psychology | 2017 |
Pituitary Adenylate Cyclase-Activating Peptide in the Bed Nucleus of the Stria Terminalis Mediates Stress-Induced Reinstatement of Cocaine Seeking in Rats.
Topics: Animals; Behavior, Addictive; Cocaine; Drug-Seeking Behavior; Electric Stimulation; Extinction, Psychological; Male; Microinjections; Peptide Fragments; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Recurrence; Self Administration; Septal Nuclei; Stress, Psychological | 2018 |
Diverse Roads to Relapse: A Discriminative Cue Signaling Cocaine Availability Is More Effective in Renewing Cocaine Seeking in Goal Trackers Than Sign Trackers and Depends on Basal Forebrain Cholinergic Activity.
Topics: Animals; Attentional Bias; Cholinergic Neurons; Cocaine; Cocaine-Related Disorders; Cues; Drug-Seeking Behavior; Male; Motivation; Prosencephalon; Rats; Rats, Sprague-Dawley; Recurrence | 2017 |
Context-induced relapse to cocaine seeking after punishment-imposed abstinence is associated with activation of cortical and subcortical brain regions.
Topics: Amygdala; Animals; Brain; Cerebral Cortex; Cocaine; Corpus Striatum; Dopamine Uptake Inhibitors; Dorsal Raphe Nucleus; Drug-Seeking Behavior; Extinction, Psychological; Habenula; Hippocampus; Male; Midline Thalamic Nuclei; Oncogene Proteins v-fos; Punishment; Rats; Rats, Sprague-Dawley; Recurrence; Substantia Nigra | 2018 |
Nicotine- and cocaine-triggered methamphetamine reinstatement in female and male Sprague-Dawley rats.
Topics: Amphetamine-Related Disorders; Animals; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Drug-Seeking Behavior; Extinction, Psychological; Female; Male; Methamphetamine; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration | 2017 |
Dissociable effects of cocaine and yohimbine on impulsive action and relapse to cocaine seeking.
Topics: Animals; Choice Behavior; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Craving; Extinction, Psychological; Impulsive Behavior; Injections, Intravenous; Male; Rats; Rats, Wistar; Reaction Time; Recurrence; Self Administration; Serial Learning; Yohimbine | 2017 |
Incubation of Accumbal Neuronal Reactivity to Cocaine Cues During Abstinence Predicts Individual Vulnerability to Relapse.
Topics: Action Potentials; Animals; Cocaine; Cocaine-Related Disorders; Cues; Extinction, Psychological; Male; Motivation; Neurons; Nucleus Accumbens; Punishment; Rats; Recurrence; Reinforcement Schedule; Self Administration | 2018 |
Reduced interhemispheric executive control network coupling in men during early cocaine abstinence: A pilot study.
Topics: Cocaine; Cocaine-Related Disorders; Executive Function; Functional Neuroimaging; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neural Pathways; Pilot Projects; Recurrence; Substance Withdrawal Syndrome; Time Factors | 2017 |
Longer treatment with alternative non-drug reinforcement fails to reduce resurgence of cocaine or alcohol seeking in rats.
Topics: Alcoholism; Animals; Central Nervous System Depressants; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Ethanol; Extinction, Psychological; Male; Rats, Long-Evans; Recurrence; Reinforcement, Psychology; Self Administration; Time Factors; Treatment Failure | 2018 |
A-Kinase Anchoring Protein 150 (AKAP150) Promotes Cocaine Reinstatement by Increasing AMPA Receptor Transmission in the Accumbens Shell.
Topics: A Kinase Anchor Proteins; Animals; Cocaine; Cocaine-Related Disorders; Dietary Sucrose; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Excitatory Postsynaptic Potentials; Genetic Vectors; Nucleus Accumbens; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Dopamine D1; Recurrence; Self Administration; Synaptic Transmission | 2018 |
Reversing Cocaine-Induced Adaptations and Reducing Relapse: An Opportunity for Repurposing Riluzole.
Topics: Cocaine; Cocaine-Related Disorders; Excitatory Amino Acid Antagonists; Humans; Recurrence; Riluzole | 2018 |
Targeting Glycine Reuptake in Alcohol Seeking and Relapse.
Topics: Alcohol Drinking; Animals; Biological Transport; Cocaine; Drug-Seeking Behavior; Ethanol; Glycine; Glycine Plasma Membrane Transport Proteins; Male; Rats; Rats, Wistar; Recurrence | 2018 |
Medial habenula cholinergic signaling regulates cocaine-associated relapse-like behavior.
Topics: Analysis of Variance; Animals; Cholinergic Neurons; Cocaine; Conditioning, Psychological; Dopamine Uptake Inhibitors; Female; Habenula; Male; Mice, Inbred C57BL; Recurrence; Signal Transduction | 2019 |
A single, extinction-based treatment with a kappa opioid receptor agonist elicits a long-term reduction in cocaine relapse.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Drug-Seeking Behavior; Extinction, Psychological; Imidazoles; Infusions, Intraventricular; Lithium Chloride; Male; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; Receptors, Opioid, kappa; Recurrence; Self Administration | 2018 |
Decrease of cocaine, but not heroin, self-administration and relapse by the tyrosine kinase inhibitor masitinib in male Sprague Dawley rats.
Topics: Administration, Oral; Analgesics, Opioid; Animals; Behavior, Addictive; Benzamides; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Heroin; Male; Motivation; Piperidines; Protein Kinase Inhibitors; Pyridines; Rats; Rats, Sprague-Dawley; Recurrence; Reinforcement, Psychology; Self Administration; Thiazoles | 2018 |
Kappa counterconditioning of cocaine cues.
Topics: Cocaine; Cues; Extinction, Psychological; Humans; Receptors, Opioid, kappa; Recurrence | 2018 |
Nucleus accumbens GLT-1a overexpression reduces glutamate efflux during reinstatement of cocaine-seeking but is not sufficient to attenuate reinstatement.
Topics: Animals; Cocaine; Dependovirus; Excitatory Amino Acid Transporter 2; Extinction, Psychological; Genetic Vectors; Glutamic Acid; Male; Nucleus Accumbens; Rats; Recurrence; Self Administration; Up-Regulation | 2018 |
Control of Cocaine Relapse: Lost in Translation.
Topics: Cocaine; Cocaine-Related Disorders; Humans; Nucleus Accumbens; Recurrence; Self Administration | 2018 |
Social reinstatement: a rat model of peer-induced relapse.
Topics: Animals; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Drug-Seeking Behavior; Extinction, Psychological; Male; Models, Animal; Peer Influence; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration | 2018 |
Effects of a histone deacetylase 3 inhibitor on extinction and reinstatement of cocaine self-administration in rats.
Topics: Acrylamides; Animals; Association Learning; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Drug-Seeking Behavior; Extinction, Psychological; Histone Deacetylase Inhibitors; Histone Deacetylases; Male; Phenylenediamines; Rats; Rats, Long-Evans; Recurrence; Reinforcement, Psychology; Self Administration | 2019 |
Differential involvement of D2 and D3 receptors during reinstatement of cocaine-seeking behavior in the Roman high- and low-avoidance rats.
Topics: Animals; Avoidance Learning; Cocaine; Conditioning, Classical; Dopamine D2 Receptor Antagonists; Drug-Seeking Behavior; Extinction, Psychological; Male; Rats; Receptors, Dopamine D2; Receptors, Dopamine D3; Recurrence; Species Specificity | 2019 |
Rate matters: rapid cocaine delivery promotes incubation of cocaine craving.
Topics: Brain-Derived Neurotrophic Factor; Cocaine; Cocaine-Related Disorders; Craving; Humans; Recurrence | 2019 |
Knockdown of the histone di-methyltransferase G9a in nucleus accumbens shell decreases cocaine self-administration, stress-induced reinstatement, and anxiety.
Topics: Animals; Anxiety; Behavior, Addictive; Behavior, Animal; Cocaine; Electric Stimulation; Extinction, Psychological; Gene Knockdown Techniques; Histone-Lysine N-Methyltransferase; Male; Nucleus Accumbens; Rats; Recurrence; Reinforcement Schedule; Self Administration | 2019 |
The effects of Pavlovian cue extinction and ceftriaxone on cocaine relapse after abstinence.
Topics: Animals; Anti-Bacterial Agents; Ceftriaxone; Cocaine; Cocaine-Related Disorders; Craving; Cues; Disease Models, Animal; Drug-Seeking Behavior; Extinction, Psychological; Male; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration | 2019 |
Discriminative stimuli are sufficient for incubation of cocaine craving.
Topics: Animals; Cocaine; Craving; Disease Models, Animal; Rats; Recurrence; Secondary Prevention; Substance-Related Disorders | 2019 |
Impaired decision making following escalation of cocaine self-administration predicts vulnerability to relapse in rats.
Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Decision Making; Disease Models, Animal; Dopamine Uptake Inhibitors; Extinction, Psychological; Male; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration | 2020 |
Break the net, break the cycle: removal of perineuronal nets in the lateral hypothalamus decreases cocaine relapse.
Topics: Cocaine; Cues; Humans; Hypothalamic Area, Lateral; Nerve Net; Receptors, N-Acetylglucosamine; Recurrence | 2019 |
Spontaneous pneumothorax in cocaine users.
Topics: Administration, Inhalation; Adult; Cocaine; Cocaine-Related Disorders; Female; Foreign Bodies; Humans; Italy; Male; Pneumothorax; Recurrence; Retrospective Studies; Thoracic Surgery, Video-Assisted; Tomography, X-Ray Computed; Treatment Outcome; Young Adult | 2019 |
Cocaine relapse and health-related quality of life: a 23 weeks study.
Topics: Adult; Cocaine; Cocaine-Related Disorders; Female; Humans; Longitudinal Studies; Male; Middle Aged; Pilot Projects; Quality of Life; Recurrence; Severity of Illness Index; Young Adult | 2019 |
Assessment of Striatal Dopamine Transporter Binding in Individuals With Major Depressive Disorder: In Vivo Positron Emission Tomography and Postmortem Evidence.
Topics: Adult; Autopsy; Carbon Radioisotopes; Cocaine; Cross-Sectional Studies; Depressive Disorder, Major; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Male; Neostriatum; Positron-Emission Tomography; Recurrence; Tissue Banks; Young Adult | 2019 |
Increased relapse to cocaine-seeking in a genetic model for depression.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cocaine; Depression; Depressive Disorder, Treatment-Resistant; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Prefrontal Cortex; Rats; Recurrence; Self Administration; Stress, Psychological | 2020 |
Extracellular Matrix Signaling Through β3 Integrin Mediates Cocaine Cue-Induced Transient Synaptic Plasticity and Relapse.
Topics: Animals; Cocaine; Cues; Dendritic Spines; Drug-Seeking Behavior; Extinction, Psychological; Integrin beta3; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Models, Neurological; Motivation; Neuronal Plasticity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Recurrence; Self Administration | 2019 |
Mechanisms underlying the efficacy of exercise as an intervention for cocaine relapse: a focus on mGlu5 in the dorsal medial prefrontal cortex.
Topics: Animals; Behavior, Addictive; Brain-Derived Neurotrophic Factor; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Male; Motor Activity; Physical Conditioning, Animal; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Recurrence; Running; Self Administration | 2019 |
Relapse to cocaine use persists following extinction of drug-primed craving.
Topics: Animals; Cocaine; Conditioning, Psychological; Craving; Extinction, Psychological; Male; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Wistar; Recurrence; Self Administration | 2019 |
N-Acetylcysteine treatment during acute stress prevents stress-induced augmentation of addictive drug use and relapse.
Topics: Acetylcysteine; Acute Disease; Alcohol-Related Disorders; Animals; Cocaine; Cocaine-Related Disorders; Cues; Disease Models, Animal; Drug-Seeking Behavior; Ethanol; Free Radical Scavengers; Male; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration; Stress, Psychological | 2020 |
Role of BRD4 phosphorylation in the nucleus accumbens in relapse to cocaine-seeking behavior in mice.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Male; Mice; Mice, Inbred C57BL; Nuclear Proteins; Nucleus Accumbens; Phosphorylation; Recurrence; Self Administration; Transcription Factors | 2020 |
Relapse to cocaine-seeking after abstinence is regulated by cAMP-dependent protein kinase A in the prefrontal cortex.
Topics: Analysis of Variance; Animals; Blotting, Western; Cocaine; CREB-Binding Protein; Cues; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Male; Neuronal Plasticity; Nucleus Accumbens; Phosphoproteins; Phosphorylation; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Recurrence; Self Administration; Synapsins; Thionucleotides | 2014 |
Relapse induced by cues predicting cocaine depends on rapid, transient synaptic potentiation.
Topics: Animals; Cell Count; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Dendritic Spines; Environment; GABA Agonists; Glutamic Acid; Long-Term Potentiation; Male; Microinjections; Microscopy, Confocal; Motivation; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, GABA; Recurrence; Self Administration; Synaptic Transmission | 2013 |
Cue-induced resumption of heroin and cocaine seeking in rats using a conflict model of abstinence and relapse.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Conflict, Psychological; Cues; Disease Models, Animal; Electroshock; Extinction, Psychological; Heroin; Heroin Dependence; Male; Rats; Rats, Long-Evans; Recurrence; Self Administration | 2013 |
Rapid, transient potentiation of dendritic spines in context-induced relapse to cocaine seeking.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Cues; Dendritic Spines; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Extinction, Psychological; Long-Term Potentiation; Male; Nucleus Accumbens; Random Allocation; Rats, Sprague-Dawley; Recurrence; Reinforcement, Psychology; Self Administration | 2014 |
The role of ventral and dorsal striatum mGluR5 in relapse to cocaine-seeking and extinction learning.
Topics: Allosteric Regulation; Analysis of Variance; Animals; Basal Ganglia; Biotinylation; Blotting, Western; Cocaine; Cocaine-Related Disorders; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Electrophysiological Phenomena; Extinction, Psychological; Infusions, Intravenous; Locomotion; Long-Term Synaptic Depression; Male; Microinjections; Pyridines; Rats; Receptor, Metabotropic Glutamate 5; Recurrence; Self Administration; Sucrose; Thiazoles | 2014 |
Differential roles of the prefrontal cortical subregions and basolateral amygdala in compulsive cocaine seeking and relapse after voluntary abstinence in rats.
Topics: Animals; Animals, Outbred Strains; Basolateral Nuclear Complex; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Electroshock; Fear; Freezing Reaction, Cataleptic; Male; Motivation; Prefrontal Cortex; Rats; Recurrence; Self Administration | 2013 |
A variant on the kappa opioid receptor gene (OPRK1) is associated with stress response and related drug craving, limbic brain activation and cocaine relapse risk.
Topics: Adult; Amygdala; Black or African American; Brain; Cerebellum; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Female; Functional Neuroimaging; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Hypothalamus; Limbic System; Magnetic Resonance Imaging; Male; Mesencephalon; Middle Aged; Pituitary-Adrenal System; Receptors, Opioid, kappa; Recurrence; Stress, Psychological; Substance Withdrawal Syndrome; Thalamus | 2013 |
Cocaine-induced leg ulceration.
Topics: Cocaine; Cocaine-Related Disorders; Drug Contamination; Female; Humans; Leg Ulcer; Levamisole; Middle Aged; Neutropenia; Recurrence | 2013 |
Cocaine-elicited imbalances in ventromedial prefrontal cortex Homer1 versus Homer2 expression: implications for relapse.
Topics: Animals; Carrier Proteins; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Homer Scaffolding Proteins; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Recurrence | 2015 |
The role of the neurokinin-1 receptor in stress-induced reinstatement of alcohol and cocaine seeking.
Topics: Adrenergic alpha-2 Receptor Antagonists; Alcohol-Related Disorders; Animals; Behavior, Addictive; Brain; Central Nervous System Depressants; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Ethanol; Male; Neurokinin-1 Receptor Antagonists; Piperidines; Rats; Rats, Long-Evans; Rats, Wistar; Receptors, Neurokinin-1; Recurrence; Saccharin; Species Specificity; Stress, Psychological; Yohimbine | 2014 |
Blockade of D3 receptors by YQA14 inhibits cocaine's rewarding effects and relapse to drug-seeking behavior in rats.
Topics: Animals; Behavior, Addictive; Behavior, Animal; Benzoxazoles; Brain; Cocaine; Cocaine-Related Disorders; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Electric Stimulation; Male; Piperazines; Rats; Rats, Long-Evans; Receptors, Dopamine D3; Recurrence; Reward | 2014 |
Post-retrieval extinction attenuates cocaine memories.
Topics: Animals; Behavior Therapy; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Dopamine Uptake Inhibitors; Extinction, Psychological; Male; Memory; Rats; Rats, Sprague-Dawley; Recurrence; Space Perception; Task Performance and Analysis | 2014 |
mTORC1 inhibition in the nucleus accumbens 'protects' against the expression of drug seeking and 'relapse' and is associated with reductions in GluA1 AMPAR and CAMKIIα levels.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Gene Expression Regulation; Mechanistic Target of Rapamycin Complex 1; Motor Activity; Multiprotein Complexes; Nucleus Accumbens; Rats; Receptors, AMPA; Recurrence; Reinforcement, Psychology; Self Administration; Sirolimus; TOR Serine-Threonine Kinases | 2014 |
Designer receptors show role for ventral pallidum input to ventral tegmental area in cocaine seeking.
Topics: Animals; Basal Ganglia; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Cues; Disease Models, Animal; Dopaminergic Neurons; Male; Neural Inhibition; Neural Pathways; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Receptors, Dopamine; Recurrence; Reward; Ventral Tegmental Area | 2014 |
Assessment of a proposed "three-criteria" cocaine addiction model for use in reinstatement studies with rats.
Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Discrimination, Psychological; Disease Models, Animal; Drug-Seeking Behavior; Extinction, Psychological; Male; Motivation; Phenotype; Photic Stimulation; Punishment; Rats; Rats, Sprague-Dawley; Recurrence; Reinforcement Schedule; Self Administration | 2014 |
Beta-2 adrenergic receptors mediate stress-evoked reinstatement of cocaine-induced conditioned place preference and increases in CRF mRNA in the bed nucleus of the stria terminalis in mice.
Topics: Adrenergic beta-Agonists; Animals; Behavior, Addictive; Clenbuterol; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Corticotropin-Releasing Hormone; Dopamine Uptake Inhibitors; Extinction, Psychological; Male; Mice; Pyrimidines; Pyrroles; Receptors, Adrenergic, beta-2; Receptors, Corticotropin-Releasing Hormone; Recurrence; Reward; Self Administration; Septal Nuclei; Stress, Psychological | 2014 |
Extinction of a cocaine-taking context that protects against drug-primed reinstatement is dependent on the metabotropic glutamate 5 receptor.
Topics: Analysis of Variance; Animals; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Extinction, Psychological; Male; Pyridines; Receptor, Metabotropic Glutamate 5; Recurrence; Reward; Self Administration; Thiazoles | 2015 |
Decision-making impairment predicts 3-month hair-indexed cocaine relapse.
Topics: Adult; Cocaine; Cocaine-Related Disorders; Cognition; Decision Making; Female; Gambling; Hair; Humans; Intelligence Tests; Male; Neuropsychological Tests; Punishment; Recurrence; Reward; Sensitivity and Specificity | 2014 |
Abdominal CT scan for recurrent seizures.
Topics: Abdomen; Adult; Capsules; Cocaine; Humans; Male; Radiography, Abdominal; Recurrence; Seizures; Tomography, X-Ray Computed | 2014 |
Lower limb ischemia due to long-term abuse of cocaine.
Topics: Angiography; Angioplasty, Balloon; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Humans; Ischemia; Lower Extremity; Male; Middle Aged; Recurrence; Regional Blood Flow; Tibial Arteries; Time Factors; Treatment Outcome; Vasoconstriction | 2016 |
Contrasting forms of cocaine-evoked plasticity control components of relapse.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopaminergic Neurons; Drug-Seeking Behavior; Female; Hippocampus; Male; Mice; N-Methylaspartate; Neural Pathways; Neuronal Plasticity; Nucleus Accumbens; Optogenetics; Prefrontal Cortex; Receptors, AMPA; Receptors, Dopamine D1; Recurrence; Synapses | 2014 |
Spontaneous pneumothorax associated with talc pulmonary granulomatosis after cocaine inhalation.
Topics: Administration, Inhalation; Adult; Cocaine; Cocaine-Related Disorders; Foreign Bodies; Humans; Lung Diseases; Male; Pneumothorax; Recurrence; Talc; Tomography, X-Ray Computed | 2016 |
α2δ-1 signaling in nucleus accumbens is necessary for cocaine-induced relapse.
Topics: Animals; Behavior, Addictive; Calcium Channels; Calcium Channels, L-Type; Cocaine; Cocaine-Related Disorders; Male; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration; Synaptic Transmission | 2014 |
[Recurrent neutropenia due to adulterated cocaine].
Topics: Adult; Agranulocytosis; Cocaine; Cocaine-Related Disorders; Drug Contamination; Humans; Levamisole; Male; Neutropenia; Recurrence | 2014 |
Abstinence from cocaine and sucrose self-administration reveals altered mesocorticolimbic circuit connectivity by resting state MRI.
Topics: Animals; Brain; Brain Mapping; Cocaine; Drug-Seeking Behavior; Hypothalamus; Magnetic Resonance Imaging; Male; Nerve Net; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Long-Evans; Recurrence; Self Administration; Sucrose | 2014 |
The galanin receptor agonist, galnon, attenuates cocaine-induced reinstatement and dopamine overflow in the frontal cortex.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Coumarins; Dopamine; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Eating; Extinction, Psychological; Frontal Lobe; Galanin; Male; Microdialysis; Motor Activity; Nucleus Accumbens; Rats, Sprague-Dawley; Recurrence; Reinforcement, Psychology; Self Administration | 2015 |
Subchronic administration of atomoxetine causes an enduring reduction in context-induced relapse to cocaine seeking without affecting impulsive decision making.
Topics: Adrenergic Uptake Inhibitors; Animals; Atomoxetine Hydrochloride; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Delay Discounting; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Extinction, Psychological; Impulsive Behavior; Male; Random Allocation; Rats, Wistar; Recurrence; Reinforcement Schedule; Self Administration | 2015 |
Cocaine-, caffeine-, and stress-evoked cocaine reinstatement in high vs. low impulsive rats: treatment with allopregnanolone.
Topics: Animals; Behavior, Addictive; Caffeine; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Delay Discounting; Extinction, Psychological; Female; Impulsive Behavior; Pregnanolone; Rats; Rats, Inbred Strains; Recurrence; Self Administration; Yohimbine | 2014 |
A novel dopamine D3 receptor antagonist YQA14 inhibits methamphetamine self-administration and relapse to drug-seeking behaviour in rats.
Topics: Animals; Behavior, Animal; Benzoxazoles; Cocaine; Cocaine-Related Disorders; Dopamine Antagonists; Drug-Seeking Behavior; Extinction, Psychological; Male; Methamphetamine; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D3; Recurrence; Reinforcement, Psychology; Self Administration | 2014 |
Synaptic plasticity mediating cocaine relapse requires matrix metalloproteinases.
Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Enzyme Activation; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neuronal Plasticity; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration | 2014 |
Cocaine influences alcohol-seeking behavior and relapse drinking in alcohol-preferring (P) rats.
Topics: Administration, Oral; Alcohol Drinking; Animals; Behavior, Animal; Cocaine; Dose-Response Relationship, Drug; Ethanol; Extinction, Psychological; Female; Models, Animal; Models, Biological; Nerve Net; Rats, Inbred Strains; Rats, Mutant Strains; Recurrence; Self Administration; Time Factors; Water | 2014 |
Resurgence of sucrose and cocaine seeking in free-feeding rats.
Topics: Animals; Cocaine; Conditioning, Operant; Drug-Seeking Behavior; Extinction, Psychological; Food Deprivation; Male; Rats; Rats, Long-Evans; Recurrence; Reinforcement Schedule; Self Administration; Sucrose | 2015 |
Chronic stimulation of the tone of endogenous anandamide reduces cue- and stress-induced relapse in rats.
Topics: Amidohydrolases; Animals; Arachidonic Acids; Benzamides; Carbamates; Cocaine; Cocaine-Related Disorders; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Endocannabinoids; Enzyme Inhibitors; Male; Polyunsaturated Alkamides; Rats, Sprague-Dawley; Recurrence; Self Administration; Stress, Physiological; Yohimbine | 2014 |
Changes in brain-derived neurotrophic factor (BDNF) during abstinence could be associated with relapse in cocaine-dependent patients.
Topics: Adolescent; Adult; Brain-Derived Neurotrophic Factor; Chronic Disease; Cocaine; Cocaine-Related Disorders; Depression; Drug-Seeking Behavior; Female; Humans; Male; Middle Aged; Recurrence; Substance Withdrawal Syndrome; Young Adult | 2015 |
Effects of prior cocaine self-administration on cognitive performance in female cynomolgus monkeys.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Cognition; Female; Learning; Macaca fascicularis; Memory, Short-Term; Recurrence; Self Administration | 2015 |
Differential vulnerability to relapse into heroin versus cocaine-seeking as a function of setting.
Topics: Animals; Behavior, Addictive; Cocaine; Environment; Heroin; Male; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration | 2015 |
Differential effects of the metabotropic glutamate 2/3 receptor agonist LY379268 on nicotine versus cocaine self-administration and relapse in squirrel monkeys.
Topics: Amino Acids; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cocaine; Cocaine-Related Disorders; Cues; Dose-Response Relationship, Drug; Drug Interactions; Drug-Seeking Behavior; Male; Nicotine; Receptors, Metabotropic Glutamate; Recurrence; Reinforcement, Psychology; Saimiri; Self Administration; Tobacco Use Disorder | 2016 |
A novel UCS memory retrieval-extinction procedure to inhibit relapse to drug seeking.
Topics: Animals; Basolateral Nuclear Complex; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Conditioning, Psychological; Cues; Drug-Seeking Behavior; Endocytosis; Extinction, Psychological; Inhibition, Psychological; Male; Mental Recall; Methylphenidate; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Recurrence; Self Administration | 2015 |
Adolescent-onset of cocaine use is associated with heightened stress-induced reinstatement of cocaine seeking.
Topics: Age of Onset; Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Corticosterone; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Electric Stimulation; Extinction, Psychological; Male; Rats; Rats, Sprague-Dawley; Recurrence; Reinforcement, Psychology; Stress, Psychological; Yohimbine | 2016 |
Cocaine-specific neuroplasticity in the ventral striatum network is linked to delay discounting and drug relapse.
Topics: Adult; Age of Onset; Cocaine; Cocaine-Related Disorders; Delay Discounting; Dopamine Uptake Inhibitors; Epidemiologic Methods; Female; Gambling; Humans; Impulsive Behavior; Magnetic Resonance Imaging; Male; Neural Pathways; Neuronal Plasticity; Recurrence; Ventral Striatum | 2015 |
A Method for Psychosocial Stress-Induced Reinstatement of Cocaine Seeking in Rats.
Topics: Adaptation, Psychological; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Corticosterone; Disease Models, Animal; Dominance-Subordination; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Extinction, Psychological; Male; Rats, Long-Evans; Recurrence; Self Administration; Stress, Psychological | 2016 |
Inhibition of Lactate Transport Erases Drug Memory and Prevents Drug Relapse.
Topics: Animals; Arabinose; Basolateral Nuclear Complex; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Imino Furanoses; Lactic Acid; Male; Memory Consolidation; Monocarboxylic Acid Transporters; Psychotropic Drugs; Rats, Sprague-Dawley; Recurrence; Secondary Prevention; Self Administration; Space Perception; Sugar Alcohols | 2016 |
Levamisole-contaminated cocaine: a hairy affair.
Topics: Adjuvants, Immunologic; Adult; Antibodies, Antineutrophil Cytoplasmic; Cocaine; Cocaine-Related Disorders; Drug Contamination; Female; Glomerulonephritis; Hair; Humans; Levamisole; Peroxidase; Recurrence; Vasculitis | 2015 |
Naloxone injections into CA3 disrupt pattern completion associated with relapse from cocaine seeking.
Topics: Animals; CA3 Region, Hippocampal; Central Nervous System Agents; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Male; Naloxone; Rats, Long-Evans; Recurrence; Spatial Behavior | 2016 |
Inhibiting subthalamic nucleus decreases cocaine demand and relapse: therapeutic potential.
Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Male; Rats; Rats, Sprague-Dawley; Recurrence; Subthalamic Nucleus | 2017 |
Effects of baclofen and raclopride on reinstatement of cocaine self-administration in the rat.
Topics: Animals; Baclofen; Behavior, Animal; Cocaine; Dopamine D2 Receptor Antagonists; Drug-Seeking Behavior; Extinction, Psychological; Male; Motivation; Raclopride; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration | 2016 |
Re-silencing of silent synapses unmasks anti-relapse effects of environmental enrichment.
Topics: Amygdala; Animals; Behavior Therapy; Cocaine; Cocaine-Related Disorders; Male; Neural Inhibition; Neural Pathways; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Recurrence; Substance Withdrawal Syndrome; Synapses; Treatment Outcome | 2016 |
Exercise during early, but not late abstinence, attenuates subsequent relapse vulnerability in a rat model.
Topics: Animals; Behavior, Addictive; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Male; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley; Recurrence; Time Factors | 2016 |
Shifted pallidal co-release of GABA and glutamate in habenula drives cocaine withdrawal and relapse.
Topics: Animals; Cocaine; gamma-Aminobutyric Acid; Glutamic Acid; Habenula; Male; Mesencephalon; Mice; Mice, Transgenic; Neural Pathways; Neurons; Recurrence; Synapses; Synaptic Transmission; Vesicular Glutamate Transport Protein 2 | 2016 |
Orexins contribute to restraint stress-induced cocaine relapse by endocannabinoid-mediated disinhibition of dopaminergic neurons.
Topics: Action Potentials; Animals; Arachidonic Acids; Cocaine; Conditioning, Classical; Dopaminergic Neurons; Endocannabinoids; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glycerides; Hypothalamic Area, Lateral; Inhibitory Postsynaptic Potentials; Male; Mice, Inbred C57BL; Models, Biological; Neural Inhibition; Orexin Receptors; Orexins; Rats, Wistar; Receptor, Cannabinoid, CB1; Recurrence; Restraint, Physical; Signal Transduction; Stress, Physiological; Synaptic Transmission; Ventral Tegmental Area | 2016 |
Metabolic shift of the kynurenine pathway impairs alcohol and cocaine seeking and relapse.
Topics: Animals; Behavior, Animal; Central Nervous System Depressants; Cocaine; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Ethanol; Kynurenine; Kynurenine 3-Monooxygenase; Male; Metabolic Networks and Pathways; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Recurrence; Self Administration; Sulfonamides; Thiazoles | 2016 |
Prior Exposure to Alcohol Has No Effect on Cocaine Self-Administration and Relapse in Rats: Evidence from a Rat Model that Does Not Support the Gateway Hypothesis.
Topics: Animals; Behavior, Addictive; Cocaine; Cues; Drug-Seeking Behavior; Ethanol; Extinction, Psychological; Models, Animal; Models, Psychological; Rats; Rats, Wistar; Recurrence; Self Administration | 2017 |
Effects of Lorcaserin on Cocaine and Methamphetamine Self-Administration and Reinstatement of Responding Previously Maintained by Cocaine in Rhesus Monkeys.
Topics: Animals; Benzazepines; Cocaine; Drug-Seeking Behavior; Female; Macaca mulatta; Male; Methamphetamine; Recurrence; Self Administration | 2016 |
Cocaine Use Reverses Striatal Plasticity Produced During Cocaine Seeking.
Topics: Animals; Cocaine; Cues; Dendritic Spines; Drug-Seeking Behavior; Extinction, Psychological; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Models, Neurological; Motivation; Neuronal Plasticity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Recurrence; Self Administration | 2017 |
PPARγ agonism attenuates cocaine cue reactivity.
Topics: Anilides; Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Craving; Cues; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Locomotion; MAP Kinase Signaling System; Pioglitazone; PPAR gamma; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration | 2018 |
Accumbens nNOS Interneurons Regulate Cocaine Relapse.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Interneurons; Male; Mice; Mice, 129 Strain; Mice, Transgenic; Nitric Oxide Synthase Type I; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Recurrence; Self Administration | 2017 |
Attenuating Nicotine Reinforcement and Relapse by Enhancing Endogenous Brain Levels of Kynurenic Acid in Rats and Squirrel Monkeys.
Topics: Animals; Cocaine; Dopamine; Isoxazoles; Kynurenic Acid; Male; Nicotine; Nucleus Accumbens; Phenylurea Compounds; Rats; Recurrence; Reinforcement, Psychology; Saimiri; Secondary Prevention; Self Administration; Sulfonamides; Thiazoles | 2017 |
Melatonin reduces motivation for cocaine self-administration and prevents relapse-like behavior in rats.
Topics: Animals; Behavior, Addictive; Behavior, Animal; Cocaine; Dose-Response Relationship, Drug; Extinction, Psychological; Male; Melatonin; Motivation; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration; Sucrose | 2017 |
Effects of repeated yohimbine on the extinction and reinstatement of cocaine seeking.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Electroshock; Extinction, Psychological; Male; Rats; Rats, Long-Evans; Recurrence; Self Administration; Stress, Psychological; Sympatholytics; Yohimbine | 2009 |
The preferential dopamine D3 receptor antagonist S33138 inhibits cocaine reward and cocaine-triggered relapse to drug-seeking behavior in rats.
Topics: Acetanilides; Animals; Benzopyrans; Cocaine; Cocaine-Related Disorders; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Electric Stimulation; Extinction, Psychological; Injections, Intravenous; Male; Motor Activity; Postural Balance; Psychomotor Performance; Rats; Rats, Long-Evans; Receptors, Dopamine D3; Recurrence; Reinforcement Schedule; Self Administration; Self Stimulation; Sucrose | 2009 |
Pronounced paranoia as a result of cocaine-disulfiram interaction: case report and mode of action.
Topics: Administration, Intranasal; Adult; Alcohol Deterrents; Alcoholism; Behavior Therapy; Cocaine; Cocaine-Related Disorders; Disulfiram; Dose-Response Relationship, Drug; Drug Interactions; Humans; Male; Paranoid Disorders; Recurrence | 2009 |
D-cycloserine potentiates the reconsolidation of cocaine-associated memories.
Topics: Amygdala; Animals; Antimetabolites; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Cycloserine; Drug Synergism; Extinction, Psychological; Male; Memory; Mental Recall; Microinjections; Rats; Recurrence | 2009 |
Cocaine-induced reinstatement during limited and extended drug access conditions in rhesus monkeys.
Topics: Animals; Catheterization; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Data Interpretation, Statistical; Infusions, Intravenous; Macaca mulatta; Male; Recurrence; Reinforcement Schedule; Self Administration | 2009 |
Role of mu- and delta-opioid receptors in the nucleus accumbens in cocaine-seeking behavior.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; beta-Endorphin; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Male; Narcotic Antagonists; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Recurrence; Reward; Self Administration; Substance Withdrawal Syndrome | 2009 |
Attenuated incubation of cocaine seeking in male rats trained to self-administer cocaine during periadolescence.
Topics: Age Factors; Animals; Behavior, Addictive; Behavior, Animal; Cocaine; Conditioning, Operant; Cues; Disease Models, Animal; Extinction, Psychological; Male; Rats; Rats, Wistar; Recurrence; Self Administration; Time Factors | 2009 |
Cocaine-evoked synaptic plasticity: persistence in the VTA triggers adaptations in the NAc.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Glutamic Acid; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Net; Neural Pathways; Neuronal Plasticity; Nucleus Accumbens; Organ Culture Techniques; Receptors, Metabotropic Glutamate; Recurrence; Substance Withdrawal Syndrome; Synaptic Transmission; Ventral Tegmental Area | 2009 |
Upregulation of GLT1 attenuates cue-induced reinstatement of cocaine-seeking behavior in rats.
Topics: Animals; Anti-Bacterial Agents; Behavior, Addictive; Ceftriaxone; Cocaine; Cocaine-Related Disorders; Cues; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Transporter 2; Extinction, Psychological; Feeding Behavior; Male; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration; Up-Regulation | 2009 |
The CB1 antagonist rimonabant (SR141716) blocks cue-induced reinstatement of cocaine seeking and other context and extinction phenomena predictive of relapse.
Topics: Animals; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Corn Oil; Cues; Dietary Sucrose; Disease Models, Animal; Extinction, Psychological; Food, Formulated; Male; Mice; Mice, Inbred C57BL; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Recurrence; Reinforcement Schedule; Rimonabant; Self Administration; Water | 2009 |
Dorsal hippocampal regulation of memory reconsolidation processes that facilitate drug context-induced cocaine-seeking behavior in rats.
Topics: Action Potentials; Analysis of Variance; Animals; Anisomycin; Basal Ganglia; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Extinction, Psychological; Hippocampus; Male; Memory; Motor Activity; Neural Conduction; Prefrontal Cortex; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration; Tetrodotoxin | 2009 |
Basolateral amygdala involvement in memory reconsolidation processes that facilitate drug context-induced cocaine seeking.
Topics: Amygdala; Analysis of Variance; Animals; Anisomycin; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Extinction, Psychological; Male; Memory; Motor Activity; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration | 2009 |
Involvement of the lateral orbitofrontal cortex in drug context-induced reinstatement of cocaine-seeking behavior in rats.
Topics: Animals; Baclofen; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Environment; Extinction, Psychological; Frontal Lobe; GABA Agonists; Male; Muscimol; Random Allocation; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration; Ventral Tegmental Area | 2009 |
Evidence for habitual and goal-directed behavior following devaluation of cocaine: a multifaceted interpretation of relapse.
Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Extinction, Psychological; Male; Neurons; Rats; Rats, Long-Evans; Recurrence; Self Administration | 2009 |
Social experiences affect reinstatement of cocaine-induced place preference in mice.
Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dose-Response Relationship, Drug; Extinction, Psychological; Female; Male; Mice; Mice, Inbred Strains; Narcotics; Recurrence; Risk Factors; Social Environment | 2009 |
Reinstatement of cocaine seeking induced by drugs, cues, and stress in adolescent and adult rats.
Topics: Age Factors; Amphetamine-Related Disorders; Animals; Behavior, Addictive; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Cues; Disease Models, Animal; Extinction, Psychological; Infusions, Intravenous; Male; Photic Stimulation; Rats; Rats, Wistar; Recurrence; Self Administration; Stress, Psychological; Time Factors; Yohimbine | 2010 |
A cocaine cue acts as an incentive stimulus in some but not others: implications for addiction.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Cues; Dopamine Uptake Inhibitors; Extinction, Psychological; Food; Individuality; Male; Photic Stimulation; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration | 2010 |
Increased error-related thalamic activity during early compared to late cocaine abstinence.
Topics: Adult; Cerebral Cortex; Cocaine; Data Interpretation, Statistical; Dopamine Uptake Inhibitors; Female; Humans; Impulsive Behavior; Magnetic Resonance Imaging; Male; Psychiatric Status Rating Scales; Psychomotor Performance; Reaction Time; Recurrence; Substance Withdrawal Syndrome; Thalamus; Time Factors | 2010 |
5-HT6 antagonism attenuates cue-induced relapse to cocaine seeking without affecting cocaine reinforcement.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Cues; Male; Pyrimidines; Random Allocation; Rats; Rats, Wistar; Receptors, Serotonin; Recurrence; Reinforcement, Psychology; Serotonin Antagonists; Sulfonamides; Thiophenes | 2010 |
Persistent increases in cocaine-seeking behavior after acute exposure to cold swim stress.
Topics: Animals; Central Nervous System Depressants; Cocaine; Cocaine-Related Disorders; Drug-Seeking Behavior; Environment; Extinction, Psychological; Male; Motivation; Rats; Rats, Sprague-Dawley; Recurrence; Reward; Self Administration; Stress, Physiological | 2010 |
Daily life hour by hour, with and without cocaine: an ecological momentary assessment study.
Topics: Adult; Affect; Cocaine; Cocaine-Related Disorders; Cohort Studies; Computers, Handheld; Female; Heroin Dependence; Humans; Male; Methadone; Middle Aged; Narcotics; Recurrence; Substance Withdrawal Syndrome; Time Factors; Young Adult | 2010 |
D-serine treatment reduces cocaine-primed reinstatement in rats following extended access to cocaine self-administration.
Topics: Animals; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Drug-Seeking Behavior; Extinction, Psychological; Male; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration; Serine; Stereoisomerism; Time Factors | 2010 |
Interaction of the rostral basolateral amygdala and prelimbic prefrontal cortex in regulating reinstatement of cocaine-seeking behavior.
Topics: Amygdala; Anesthetics, Local; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Data Interpretation, Statistical; Extinction, Psychological; Functional Laterality; Lidocaine; Limbic System; Male; Neural Pathways; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Rats, Wistar; Recurrence; Reinforcement Schedule; Self Administration | 2010 |
Recurrent ventricular arrhythmias and myocardial infarctions associated with cocaine induced reversible coronary vasospasm.
Topics: Cocaine; Cocaine-Related Disorders; Coronary Angiography; Coronary Vasospasm; Defibrillators, Implantable; Electrocardiography; Humans; Male; Middle Aged; Myocardial Infarction; Recurrence; Vasoconstrictor Agents; Ventricular Fibrillation | 2010 |
Neuropeptide S facilitates cue-induced relapse to cocaine seeking through activation of the hypothalamic hypocretin system.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Cues; Drug Administration Routes; Hypothalamus; Intracellular Signaling Peptides and Proteins; Neurons; Neuropeptides; Neurotransmitter Agents; Orexins; Rats; Rats, Long-Evans; Recurrence | 2010 |
[Massive destructive sinusitis following cocaine inhalation].
Topics: Administration, Inhalation; Brain Diseases; Cocaine; Cocaine-Related Disorders; Facial Bones; Fatal Outcome; Female; Humans; Ischemia; Maxillary Sinus; Maxillary Sinusitis; Nose; Palate; Paranasal Sinuses; Recurrence; Young Adult | 2012 |
A procedure for studying the footshock-induced reinstatement of cocaine seeking in laboratory rats.
Topics: Animals; Behavior, Addictive; Cocaine; Conditioning, Operant; Disease Models, Animal; Electroshock; Extinction, Psychological; Male; Rats; Rats, Inbred LEC; Recurrence; Stress, Psychological | 2011 |
Activation of D₂-like receptors in rat ventral tegmental area inhibits cocaine-reinstated drug-seeking behavior.
Topics: Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Dopamine Agonists; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Extinction, Psychological; Male; Neurons; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Recurrence; Self Administration; Substance-Related Disorders; Ventral Tegmental Area | 2011 |
Chronic N-acetylcysteine during abstinence or extinction after cocaine self-administration produces enduring reductions in drug seeking.
Topics: Acetylcysteine; Animals; Cocaine; Cocaine-Related Disorders; Cues; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Extinction, Psychological; Glutamic Acid; Homeostasis; Male; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration; Substance Withdrawal Syndrome | 2011 |
Synaptic adaptations in the nucleus accumbens caused by experiences linked to relapse.
Topics: Analysis of Variance; Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Extinction, Psychological; Male; Mice; Motor Activity; Neurons; Nucleus Accumbens; Patch-Clamp Techniques; Recurrence; Synapses; Synaptic Transmission | 2011 |
Adolescent nicotine exposure sensitizes cue-induced reinstatement of cocaine seeking in rats bred for high and low saccharin intake.
Topics: Animals; Behavior, Addictive; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Disease Models, Animal; Extinction, Psychological; Female; Gene-Environment Interaction; Nicotine; Phenotype; Rats; Rats, Sprague-Dawley; Recurrence; Saccharin; Self Administration; Sweetening Agents | 2011 |
Subregion-specific role of glutamate receptors in the nucleus accumbens on drug context-induced reinstatement of cocaine-seeking behavior in rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Drug-Seeking Behavior; Extinction, Psychological; Feeding Behavior; Male; Motivation; Motor Activity; Nucleus Accumbens; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Recurrence; Reinforcement, Psychology; Self Administration | 2012 |
Regulation of cocaine-induced reinstatement by group II metabotropic glutamate receptors in the ventral tegmental area.
Topics: Amino Acids; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Extinction, Psychological; Male; Microinjections; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Recurrence; Self Administration; Ventral Tegmental Area | 2012 |
Propensity to 'relapse' following exposure to cocaine cues is associated with the recruitment of specific thalamic and epithalamic nuclei.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Cues; Dopamine Uptake Inhibitors; Epithalamus; Immunohistochemistry; Male; Rats; Rats, Sprague-Dawley; Recurrence; Thalamus | 2011 |
Genetic differences in the modulation of accumbal glutamate and γ-amino butyric acid levels after cocaine-induced reinstatement.
Topics: Analysis of Variance; Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Electrophoresis, Capillary; Extinction, Psychological; gamma-Aminobutyric Acid; Genetic Predisposition to Disease; Glutamic Acid; Microdialysis; Nucleus Accumbens; Rats; Rats, Inbred F344; Rats, Inbred Lew; Recurrence; Self Administration; Sodium Chloride; Species Specificity | 2013 |
The effect of N-acetylcysteine in the nucleus accumbens on neurotransmission and relapse to cocaine.
Topics: Acetylcysteine; Animals; Cocaine; Cystine; Drug-Seeking Behavior; Excitatory Postsynaptic Potentials; Free Radical Scavengers; Glutamic Acid; Male; Nucleus Accumbens; Patch-Clamp Techniques; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Recurrence; Synaptic Transmission | 2012 |
Role of mGluR5 neurotransmission in reinstated cocaine-seeking.
Topics: Analysis of Variance; Animals; Biotinylation; Blotting, Western; Carrier Proteins; Cocaine; Cocaine-Related Disorders; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Excitatory Amino Acid Agonists; Extinction, Psychological; Glycine; Homer Scaffolding Proteins; Male; Microinjections; Nucleus Accumbens; Phenylacetates; Protein Binding; Protein Transport; Pyridines; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Recurrence; Self Administration; Synaptic Transmission; Thiazoles | 2013 |
Multicenter assessment of the revisit risk for a further drug-related problem in the emergency department in cocaine users (MARRIED-cocaine study).
Topics: Adolescent; Adult; Aged; Cocaine; Cocaine-Related Disorders; Cohort Studies; Emergency Service, Hospital; Female; Hospitalization; Humans; Male; Middle Aged; Patient Admission; Recurrence; Retrospective Studies; Risk Factors; Spain; Survival Analysis; Young Adult | 2012 |
Differential effects of cocaine access and withdrawal on glutamate type 1 transporter expression in rat nucleus accumbens core and shell.
Topics: Animals; Blotting, Western; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Glucose Transporter Type 1; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Recurrence | 2012 |
Effects of acupuncture on stress-induced relapse to cocaine-seeking in rats.
Topics: Acupuncture Therapy; Animals; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Gene Expression Regulation; Male; Nucleus Accumbens; Phosphorylation; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration; Stress, Psychological | 2012 |
A memory retrieval-extinction procedure to prevent drug craving and relapse.
Topics: Amygdala; Animals; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Conditioning, Classical; Conditioning, Operant; Cues; Extinction, Psychological; Heroin; Heroin Dependence; Humans; Male; Memory; Mental Recall; Models, Animal; Prefrontal Cortex; Protein Kinase C; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration; Time Factors | 2012 |
Treatment of cocaine withdrawal anxiety with guanfacine: relationships to cocaine intake and reinstatement of cocaine seeking in rats.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Cocaine; Drug-Seeking Behavior; Extinction, Psychological; Guanfacine; Male; Maze Learning; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration; Substance Withdrawal Syndrome | 2012 |
Reinstatement of cocaine seeking in rats by the pharmacological stressors, corticotropin-releasing factor and yohimbine: role for D1/5 dopamine receptors.
Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Behavior, Addictive; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Corticotropin-Releasing Hormone; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Extinction, Psychological; Infusions, Intraventricular; Infusions, Parenteral; Injections, Intravenous; Male; Rats; Rats, Long-Evans; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Dopamine D3; Recurrence; Self Administration; Sucrose; Time Factors; Yohimbine | 2012 |
Time course of cocaine-induced behavioral and neurochemical plasticity.
Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Glutamic Acid; Male; Neuronal Plasticity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration; Substance Withdrawal Syndrome; Time Factors | 2014 |
A drug-paired taste cue elicits withdrawal and predicts cocaine self-administration.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Rats; Rats, Sprague-Dawley; Recurrence; Reward; Saccharin; Substance Withdrawal Syndrome; Sweetening Agents; Taste | 2013 |
Hippocampal neurogenesis protects against cocaine-primed relapse.
Topics: Analysis of Variance; Animals; Bromodeoxyuridine; Caspase 3; Cocaine; Cocaine-Related Disorders; Cues; Dentate Gyrus; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Electric Stimulation; Extinction, Psychological; Hippocampus; Male; Neurogenesis; Neurons; Rats; Rats, Wistar; Recurrence; Self Administration | 2014 |
Effect of cocaine and sucrose withdrawal period on extinction behavior, cue-induced reinstatement, and protein levels of the dopamine transporter and tyrosine hydroxylase in limbic and cortical areas in rats.
Topics: Animals; Cerebral Cortex; Cocaine; Conditioning, Operant; Cues; Dopamine Plasma Membrane Transport Proteins; Extinction, Psychological; Immunoblotting; Limbic System; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Rats; Rats, Long-Evans; Recurrence; Reward; Self Administration; Substance Withdrawal Syndrome; Sucrose; Tyrosine 3-Monooxygenase | 2002 |
Reinstatement and spontaneous recovery of cocaine-seeking following extinction and different durations of withdrawal.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Extinction, Psychological; Male; Rats; Recurrence; Reinforcement Schedule; Self Administration; Substance Withdrawal Syndrome | 2002 |
Association of cocaine withdrawal symptoms with more severe dependence and enhanced subjective response to cocaine.
Topics: Adult; Arousal; Cocaine; Cocaine-Related Disorders; Drug Synergism; Euphoria; Female; Humans; Male; Recurrence; Substance Withdrawal Syndrome | 2003 |
Prefrontal glutamate release into the core of the nucleus accumbens mediates cocaine-induced reinstatement of drug-seeking behavior.
Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Disease Models, Animal; Dopamine; Extinction, Psychological; Extracellular Space; GABA Agonists; Glutamic Acid; Male; Microdialysis; Neurons; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Recurrence; Reinforcement, Psychology; Self Administration | 2003 |
Conditioned stimulus-induced reinstatement of extinguished cocaine seeking in C57BL/6 mice: a mouse model of drug relapse.
Topics: Animals; Behavior, Addictive; Cocaine; Conditioning, Psychological; Disease Models, Animal; Dose-Response Relationship, Drug; Mice; Mice, Inbred C57BL; Recurrence; Reinforcement, Psychology | 2003 |
Manipulation of dopamine d1-like receptor activation in the rat medial prefrontal cortex alters stress- and cocaine-induced reinstatement of conditioned place preference behavior.
Topics: Animals; Behavior, Animal; Benzazepines; Cocaine; Conditioning, Psychological; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Extinction, Psychological; Immobilization; Male; Motor Activity; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Recurrence; Stress, Physiological; Time Factors | 2003 |
Neuroadaptations in cystine-glutamate exchange underlie cocaine relapse.
Topics: Acetylcysteine; Adaptation, Physiological; Analysis of Variance; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Corpus Striatum; Cystine; Dose-Response Relationship, Drug; Expectorants; Extinction, Psychological; Extracellular Space; Glutamic Acid; Male; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Recurrence; Reinforcement, Psychology; Self Administration; Substance Withdrawal Syndrome; Time Factors | 2003 |
Persistent cue-evoked activity of accumbens neurons after prolonged abstinence from self-administered cocaine.
Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Cues; Discrimination Learning; Evoked Potentials, Auditory; Kinetics; Male; Neurons; Nucleus Accumbens; Rats; Rats, Long-Evans; Recurrence; Reward; Self Administration | 2003 |
Limbic and motor circuitry underlying footshock-induced reinstatement of cocaine-seeking behavior.
Topics: Amygdala; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Disease Models, Animal; Dopamine; Dopamine Antagonists; Efferent Pathways; Electroshock; GABA Agonists; Globus Pallidus; Glutamic Acid; Limbic System; Male; Microinjections; Motor Activity; Neostriatum; Neural Inhibition; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration; Septal Nuclei; Ventral Tegmental Area | 2004 |
Effects of extended access to high versus low cocaine doses on self-administration, cocaine-induced reinstatement and brain mRNA levels in rats.
Topics: Animals; Behavior, Addictive; Brain; Cocaine; Cocaine-Related Disorders; Corticotropin-Releasing Hormone; Dose-Response Relationship, Drug; Dynorphins; Enkephalins; Extinction, Psychological; Male; Opioid Peptides; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Recurrence; RNA, Messenger; Self Administration; Time Factors | 2004 |
Differential effects of dopaminergic agents on locomotor sensitisation and on the reinstatement of cocaine-seeking and food-seeking behaviour.
Topics: Animals; Benzazepines; Cocaine; Cocaine-Related Disorders; Cues; Dopamine Agonists; Dopamine Uptake Inhibitors; Extinction, Psychological; Feeding Behavior; Male; Motor Activity; Photic Stimulation; Quinolines; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Dopamine D3; Recurrence; Reward; Tetrahydronaphthalenes | 2004 |
Cocaine seeking over extended withdrawal periods in rats: time dependent increases of responding induced by heroin priming over the first 3 months.
Topics: Animals; Behavior, Addictive; Cocaine; Conditioning, Operant; Disease Models, Animal; Drug Administration Schedule; Extinction, Psychological; Forecasting; Heroin; Injections, Intravenous; Injections, Subcutaneous; Male; Rats; Rats, Long-Evans; Recurrence; Self Administration; Substance Withdrawal Syndrome; Time Factors | 2004 |
Cocaine seeking over extended withdrawal periods in rats: different time courses of responding induced by cocaine cues versus cocaine priming over the first 6 months.
Topics: Animals; Behavior, Addictive; Cocaine; Conditioning, Operant; Cues; Drug Administration Schedule; Drug Evaluation, Preclinical; Extinction, Psychological; Infusion Pumps; Injections, Intraperitoneal; Male; Rats; Rats, Long-Evans; Recurrence; Self Administration; Substance Withdrawal Syndrome; Time Factors | 2004 |
Differential involvement of the core and shell subregions of the nucleus accumbens in conditioned cue-induced reinstatement of cocaine seeking in rats.
Topics: Acoustic Stimulation; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Extinction, Psychological; Injections; Male; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration | 2004 |
Differential involvement of orbitofrontal cortex subregions in conditioned cue-induced and cocaine-primed reinstatement of cocaine seeking in rats.
Topics: Animals; Baclofen; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Cues; Extinction, Psychological; Frontal Lobe; Infusions, Intravenous; Male; Motor Activity; Muscimol; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration | 2004 |
Ethical issues in using a cocaine vaccine to treat and prevent cocaine abuse and dependence.
Topics: Cocaine; Cocaine-Related Disorders; Coercion; Ethics, Medical; Humans; Legislation, Drug; Recurrence; Vaccines | 2004 |
Interaction of noncontingent cocaine and contingent drug-paired stimuli on cocaine reinstatement.
Topics: Acoustic Stimulation; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Administration Schedule; Infusions, Intravenous; Male; Photic Stimulation; Rats; Rats, Sprague-Dawley; Recurrence; Reinforcement Schedule; Self Administration | 2004 |
Repeated maternal separation: differences in cocaine-induced behavioral sensitization in adult male and female mice.
Topics: Animals; Arousal; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Dopamine Plasma Membrane Transport Proteins; Female; gamma-Aminobutyric Acid; Hippocampus; Hypothalamo-Hypophyseal System; Male; Maternal Deprivation; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Motor Activity; Nerve Tissue Proteins; Nucleus Accumbens; Pituitary-Adrenal System; Receptors, Glucocorticoid; Recurrence; Risk Factors; Sex Factors | 2005 |
Acute administration of SB-277011A, NGB 2904, or BP 897 inhibits cocaine cue-induced reinstatement of drug-seeking behavior in rats: role of dopamine D3 receptors.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Extinction, Psychological; Fluorenes; Male; Nitriles; Photic Stimulation; Piperazines; Rats; Rats, Long-Evans; Receptors, Dopamine D3; Recurrence; Self Administration; Tetrahydroisoquinolines | 2005 |
Prazosin, an alpha-1 adrenergic antagonist, reduces cocaine-induced reinstatement of drug-seeking.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dose-Response Relationship, Drug; Food; Male; Prazosin; Rats; Rats, Sprague-Dawley; Recurrence; Reinforcement Schedule; Reward | 2005 |
Potentiation of cocaine-primed reinstatement of drug seeking in female rats during estrus.
Topics: Animals; Cocaine; Conditioning, Operant; Estrus; Extinction, Psychological; Female; Male; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration; Sex Characteristics | 2005 |
Activation of central neurokinin-1 receptors induces reinstatement of cocaine-seeking behavior.
Topics: Animals; Behavior, Addictive; Behavior, Animal; Brain; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Indoles; Infusions, Intravenous; Isoindoles; Male; Physalaemin; Rats; Rats, Wistar; Receptors, Neurokinin-1; Recurrence; Self Administration | 2005 |
Neuronal substrates of relapse to cocaine-seeking behavior: role of prefrontal cortex.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dopamine; Electroencephalography; Evoked Potentials; Feedback; Glutamic Acid; Male; Motivation; Nerve Net; Neurons; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration; Substance Withdrawal Syndrome | 2005 |
Central injections of CRF reinstate cocaine seeking in rats after postinjection delays of up to 3 h: an influence of time and environmental context.
Topics: Animals; Brain; Cocaine; Corticotropin-Releasing Hormone; Injections, Intraventricular; Male; Rats; Rats, Long-Evans; Recurrence; Self Administration; Time Factors | 2006 |
Cannabinoid CB1 receptor antagonist AM251 inhibits cocaine-primed relapse in rats: role of glutamate in the nucleus accumbens.
Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Dopamine; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Male; Nucleus Accumbens; Piperidines; Pyrazoles; Rats; Rats, Long-Evans; Receptor, Cannabinoid, CB1; Recurrence; Reward | 2006 |
The influence of reinforcing effects of cocaine on cocaine-induced increases in extinguished responding in cynomolgus monkeys.
Topics: Animals; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dose-Response Relationship, Drug; Extinction, Psychological; Food; Injections, Intravenous; Macaca fascicularis; Male; Recurrence; Reinforcement, Psychology; Self Administration | 2007 |
Selective inactivation of the ventral hippocampus attenuates cue-induced and cocaine-primed reinstatement of drug-seeking in rats.
Topics: Analysis of Variance; Animals; Appetitive Behavior; Association Learning; Cocaine; Conditioning, Classical; Cues; Dopamine Uptake Inhibitors; Hippocampus; Male; Mental Recall; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration | 2007 |
Levo-tetrahydropalmatine attenuates cocaine self-administration and cocaine-induced reinstatement in rats.
Topics: Animals; Berberine Alkaloids; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Corydalis; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D3; Recurrence; Self Administration; Stephania; Stereoisomerism | 2007 |
Can't get enough of that dopamine.
Topics: Antipsychotic Agents; Basal Ganglia; Cocaine; Cocaine-Related Disorders; Dopamine; Euphoria; Humans; Mental Disorders; Mood Disorders; Receptors, Dopamine; Recurrence; Synaptic Transmission | 2007 |
Stress-induced relapse to cocaine seeking: roles for the CRF(2) receptor and CRF-binding protein in the ventral tegmental area of the rat.
Topics: Animals; Behavior, Animal; Carrier Proteins; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Corticotropin-Releasing Hormone; Dopamine; Electroshock; Glutamic Acid; Male; Protein Binding; Rats; Rats, Long-Evans; Receptors, Corticotropin-Releasing Hormone; Recurrence; Self Administration; Stress, Psychological; Ventral Tegmental Area | 2007 |
When administered into the nucleus accumbens core or shell, the NMDA receptor antagonist AP-5 reinstates cocaine-seeking behavior in the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Exploratory Behavior; Glutamic Acid; Male; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Recurrence | 2007 |
A conflict rat model of cue-induced relapse to cocaine seeking.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Conflict, Psychological; Cues; Disease Models, Animal; Electroshock; Extinction, Psychological; Infusions, Intravenous; Male; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration; Time Factors | 2007 |
The role of dorsal vs ventral striatal pathways in cocaine-seeking behavior after prolonged abstinence in rats.
Topics: Animals; Basal Ganglia; Behavior, Addictive; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Male; Rats; Rats, Sprague-Dawley; Recurrence; Reinforcement, Psychology; Self Administration; Substance Withdrawal Syndrome; Substantia Nigra | 2007 |
Chronic cocaine reduces RGS4 mRNA in rat prefrontal cortex and dorsal striatum.
Topics: Animals; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Down-Regulation; Drug Administration Schedule; Male; Neostriatum; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, G-Protein-Coupled; Recurrence; RGS Proteins; RNA, Messenger; Self Administration; Substance Withdrawal Syndrome | 2007 |
A role for BDNF in cocaine reward and relapse.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cocaine; Cocaine-Related Disorders; Humans; Nucleus Accumbens; Recurrence; Reward | 2007 |
Footshock stress reinstates cocaine seeking in rats after extended post-stress delays.
Topics: Animals; Behavior, Addictive; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Electroshock; Extinction, Psychological; Infusion Pumps, Implantable; Male; Rats; Rats, Long-Evans; Recurrence; Self Administration; Stress, Psychological; Time Factors; Vasoconstrictor Agents | 2007 |
Cocaine craving as a predictor of treatment attrition and outcomes after residential treatment for cocaine dependence.
Topics: Adult; Affect; Cocaine; Cocaine-Related Disorders; Cues; Drive; Female; Follow-Up Studies; Humans; Male; Motivation; Patient Admission; Patient Dropouts; Recurrence; Social Environment; Substance Abuse Detection; Substance Abuse Treatment Centers; Substance Withdrawal Syndrome | 2007 |
Acamprosate attenuates cocaine- and cue-induced reinstatement of cocaine-seeking behavior in rats.
Topics: Acamprosate; Alcohol Deterrents; Animals; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Dose-Response Relationship, Drug; Extinction, Psychological; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration; Taurine | 2007 |
Stressor- and corticotropin releasing factor-induced reinstatement and active stress-related behavioral responses are augmented following long-access cocaine self-administration by rats.
Topics: Animals; Anxiety; Arousal; Cocaine; Cocaine-Related Disorders; Corticotropin-Releasing Hormone; Extinction, Psychological; Fear; Male; Maze Learning; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration; Social Environment; Stress, Psychological | 2008 |
Effects of progesterone on the reinstatement of cocaine-seeking behavior in female rats.
Topics: Animals; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Estradiol; Estrogens; Extinction, Psychological; Female; Infusions, Intravenous; Ovariectomy; Progesterone; Progestins; Rats; Rats, Wistar; Recurrence; Reinforcement Schedule; Self Administration | 2007 |
Effects of gabapentin on cocaine self-administration, cocaine-triggered relapse and cocaine-enhanced nucleus accumbens dopamine in rats.
Topics: Amines; Animals; Anti-Anxiety Agents; Cocaine; Cocaine-Related Disorders; Cyclohexanecarboxylic Acids; Disruptive, Impulse Control, and Conduct Disorders; Dopamine; Gabapentin; gamma-Aminobutyric Acid; Male; Nucleus Accumbens; Rats; Rats, Long-Evans; Recurrence; Self Administration; Vasoconstrictor Agents | 2008 |
Progesterone attenuates cocaine-induced conditioned place preference in female rats.
Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Disease Models, Animal; Female; Learning; Memory Disorders; Menstrual Cycle; Neuropsychological Tests; Progesterone; Rats; Rats, Inbred F344; Recognition, Psychology; Recurrence; Reward; Sex Characteristics | 2008 |
Level of operant training rather than cocaine intake predicts level of reinstatement.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dose-Response Relationship, Drug; Extinction, Psychological; Injections, Intravenous; Male; Rats; Rats, Wistar; Recurrence; Reinforcement Schedule; Self Administration | 2008 |
Wheel-running behavior is altered following withdrawal from repeated cocaine in adult rats.
Topics: Analysis of Variance; Animals; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Exploratory Behavior; Habituation, Psychophysiologic; Male; Motivation; Motor Activity; Rats; Rats, Sprague-Dawley; Recurrence; Reward; Statistics, Nonparametric; Substance Withdrawal Syndrome | 2008 |
Genetic liability increases propensity to prime-induced reinstatement of conditioned place preference in mice exposed to low cocaine.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Dose-Response Relationship, Drug; Extinction, Psychological; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Recurrence; Species Specificity | 2008 |
Relapse to cocaine-seeking increases activity-regulated gene expression differentially in the striatum and cerebral cortex of rats following short or long periods of abstinence.
Topics: Analysis of Variance; Animals; Autoradiography; Behavior, Addictive; Cerebral Cortex; Cocaine; Corpus Striatum; Cytoskeletal Proteins; Early Growth Response Protein 1; Gene Expression; Gene Expression Profiling; In Situ Hybridization; Male; Nerve Tissue Proteins; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Recurrence; RNA, Messenger; Self Administration; Substance Withdrawal Syndrome; Time Factors | 2008 |
Hippocampal regulation of contextual cue-induced reinstatement of cocaine-seeking behavior.
Topics: Acoustic Stimulation; Anesthetics, Local; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Food; Hippocampus; Lidocaine; Male; Microinjections; Rats; Rats, Wistar; Recurrence; Reinforcement Schedule; Self Administration; Smell | 2008 |
Anterior uveitis in Papua New Guinea.
Topics: Atropine; Cocaine; Epinephrine; Humans; Leprosy; Papua New Guinea; Recurrence; Uveitis, Anterior | 1981 |
[Drug-induced psychoses].
Topics: Affective Disorders, Psychotic; Amphetamines; Cocaine; Delusions; Diagnosis, Differential; Hallucinations; Hallucinogens; Humans; Neurotic Disorders; Psychoses, Substance-Induced; Recurrence; Substance-Related Disorders | 1982 |
The influence of endobronchial fluid on the ventilation.
Topics: Adult; Aged; Anesthetics, Local; Bronchi; Bronchitis; Cocaine; Contrast Media; Female; Forced Expiratory Volume; Humans; Lidocaine; Male; Maximal Midexpiratory Flow Rate; Middle Aged; Recurrence; Respiratory Function Tests; Vital Capacity | 1980 |
Craving in hospitalized cocaine abusers as a predictor of outcome.
Topics: Adult; Cocaine; Female; Follow-Up Studies; Humans; Length of Stay; Male; Motivation; Neurologic Examination; Patient Admission; Recurrence; Risk Factors; Social Environment; Substance Abuse Treatment Centers; Substance Withdrawal Syndrome; Substance-Related Disorders; Treatment Outcome | 1995 |
Intermittent cocaine use associated with recurrent dissection of the thoracic and abdominal aorta.
Topics: Adult; Aortic Aneurysm; Aortic Dissection; Aortography; Chest Pain; Cocaine; Humans; Male; Recurrence; Substance-Related Disorders | 1995 |
Social settings and addiction relapse.
Topics: Adult; Alcoholism; Cocaine; Female; Humans; Longitudinal Studies; Male; Middle Aged; Motivation; Recurrence; Risk Factors; Social Environment; Social Facilitation; Substance-Related Disorders | 1995 |
An examination of the cocaine relapse process.
Topics: Adult; Affect; Arousal; Cocaine; Female; Follow-Up Studies; Humans; Internal-External Control; Male; Personality Assessment; Psychometrics; Recurrence; Risk Factors; Social Environment; Social Support; Substance Withdrawal Syndrome; Substance-Related Disorders; Treatment Outcome | 1995 |
Autonomous psychosis following psychotogenic substance abuse.
Topics: Cocaine; Dronabinol; Female; Humans; Lysergic Acid Diethylamide; Male; Middle Aged; Psychoses, Substance-Induced; Psychotropic Drugs; Recurrence; Risk Factors; Schizophrenia | 1995 |
Repeat users of substance abuse services at a VA Medical Center.
Topics: Adult; Aged; Alcoholism; Cocaine; Comorbidity; Female; Health Services Misuse; Heroin Dependence; Hospitals, Veterans; Humans; Ill-Housed Persons; Male; Middle Aged; Recurrence; San Francisco; Substance-Related Disorders; Treatment Outcome; Veterans | 1995 |
General and specific locus of control in cocaine abusers.
Topics: Adult; Cocaine; Female; Humans; Internal-External Control; Male; Patient Readmission; Personality Inventory; Psychometrics; Recurrence; Reproducibility of Results; Substance-Related Disorders | 1994 |
Dissociation of "conscious desire" (craving) from and relapse in alcohol and cocaine dependence.
Topics: Adult; Alcoholism; Awareness; Cocaine; Diagnosis, Dual (Psychiatry); Ethanol; Female; Follow-Up Studies; Humans; Male; Middle Aged; Motivation; Recurrence; Rehabilitation Centers; Risk Factors; Substance Withdrawal Syndrome; Substance-Related Disorders; Treatment Outcome | 1994 |
Inhibition of corticosterone synthesis by Metyrapone decreases cocaine-induced locomotion and relapse of cocaine self-administration.
Topics: Analysis of Variance; Animals; Cocaine; Corticosterone; Male; Motor Activity; Pyridines; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration; Substance-Related Disorders | 1994 |
The dopamine D2 receptor gene: a genetic risk factor in substance abuse.
Topics: Adult; Aggression; Alcoholism; Alleles; Amphetamines; Cocaine; Deoxyribonucleases, Type II Site-Specific; Female; Genetic Carrier Screening; Humans; Male; Middle Aged; Models, Statistical; Receptors, Dopamine D2; Recurrence; Risk Factors; Substance-Related Disorders; Violence | 1994 |
Reentry monitoring in the treatment of physicians with substance dependence.
Topics: Alcoholism; Cocaine; Dentists; Female; Follow-Up Studies; Humans; Louisiana; Male; Pharmacists; Physician Impairment; Professional Impairment; Psychotherapy, Group; Recurrence; Students, Medical; Substance-Related Disorders | 1994 |
Investigating onset, cessation, relapse, and recovery: why you should, and how you can, use discrete-time survival analysis to examine event occurrence.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Cocaine; Depressive Disorder; Female; Humans; Life Change Events; Male; Middle Aged; Personality Assessment; Personality Development; Proportional Hazards Models; Recurrence; Risk Factors; Substance-Related Disorders; Suicide; Suicide Prevention; Survival Analysis; Treatment Outcome | 1993 |
ARRIVE: an AIDS education/relapse prevention model for high-risk parolees.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aftercare; AIDS Serodiagnosis; Cocaine; Combined Modality Therapy; Female; Health Education; Health Knowledge, Attitudes, Practice; Heroin Dependence; Humans; Male; Outcome and Process Assessment, Health Care; Prisoners; Recurrence; Risk Factors; Self-Help Groups; Substance Abuse, Intravenous | 1994 |
Correlates of drug injection behaviors among methadone outpatients.
Topics: Acquired Immunodeficiency Syndrome; Adult; Cocaine; Female; Health Knowledge, Attitudes, Practice; Heroin Dependence; Humans; Male; Methadone; Middle Aged; Needle Sharing; Recurrence; Risk-Taking; Substance Abuse, Intravenous | 1993 |
Alcoholism in treatment-seeking cocaine abusers: clinical and prognostic significance.
Topics: Adult; Alcoholism; Antisocial Personality Disorder; Cocaine; Comorbidity; Connecticut; Cross-Sectional Studies; Female; Follow-Up Studies; Humans; Incidence; Male; Mental Disorders; Outcome Assessment, Health Care; Patient Acceptance of Health Care; Recurrence; Substance-Related Disorders | 1993 |
Cocaine-related movement disorders.
Topics: Adult; Cocaine; Dyskinesia, Drug-Induced; Dystonia; Female; Humans; Male; Neurologic Examination; Recurrence; Substance-Related Disorders; Tourette Syndrome; Tremor | 1993 |
Disability payments among schizophrenic cocaine abusers.
Topics: Cocaine; Humans; Male; Public Assistance; Recurrence; Substance-Related Disorders; United States | 1996 |
Opposite modulation of cocaine-seeking behavior by D1- and D2-like dopamine receptor agonists.
Topics: Animals; Behavior, Addictive; Behavior, Animal; Benzazepines; Caffeine; Cocaine; Dopamine Agonists; Ergolines; Male; Motor Activity; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Recurrence; Reinforcement, Psychology; Substance-Related Disorders; Tetrahydronaphthalenes | 1996 |
Alcohol-related seizures and the kindling effect of repeated detoxifications: the influence of cocaine.
Topics: Adult; Alcohol Withdrawal Delirium; Alcoholism; Cocaine; Combined Modality Therapy; Comorbidity; Electroencephalography; Female; Humans; Kindling, Neurologic; Male; Middle Aged; Opioid-Related Disorders; Recurrence; Risk Factors; Seizures; Treatment Outcome | 1996 |
Treatment outcomes for methadone clients receiving lump-sum payments at initiation of disability benefits.
Topics: Adult; Ambulatory Care; Cocaine; Disability Evaluation; Eligibility Determination; Female; Financial Management; HIV Infections; Humans; Income; Insurance, Disability; Male; Methadone; Middle Aged; Opioid-Related Disorders; Recurrence; San Francisco; Social Security; Substance Abuse Detection; Substance Abuse, Intravenous; Substance-Related Disorders; Treatment Outcome | 1996 |
Development of the cocaine relapse interview: an initial report.
Topics: Adult; Cocaine; Female; Humans; Interview, Psychological; Male; Middle Aged; Recurrence; Reproducibility of Results; Substance-Related Disorders | 1996 |
Effects of dopaminergic and glutamatergic receptor antagonists on the establishment and expression of conditioned locomotion to cocaine in rats.
Topics: Analysis of Variance; Animals; Benzazepines; Cocaine; Conditioning, Psychological; Dizocilpine Maleate; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Locomotion; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Recurrence; Substance-Related Disorders; Sulpiride | 1996 |
Gender differences in the relapse experiences of cocaine patients.
Topics: Adolescent; Adult; Affect; Ambulatory Care; Cocaine; Female; Hospitalization; Humans; Interpersonal Relations; Male; Opioid-Related Disorders; Psychiatric Status Rating Scales; Recurrence; Sex Factors; Treatment Outcome | 1996 |
Craving for alcohol and cocaine: from inside the brain to the clinic.
Topics: Alcoholism; Brain; Cocaine; Cues; Humans; Motivation; Neurotransmitter Agents; Opioid-Related Disorders; Receptors, Dopamine; Recurrence; Tomography, Emission-Computed | 1996 |
Frontal P300 decrements, childhood conduct disorder, family history, and the prediction of relapse among abstinent cocaine abusers.
Topics: Adult; Antisocial Personality Disorder; Arousal; Attention; Child; Child Behavior Disorders; Cocaine; Electroencephalography; Event-Related Potentials, P300; Female; Frontal Lobe; Humans; Male; Recurrence; Signal Processing, Computer-Assisted; Substance-Related Disorders; Treatment Outcome | 1997 |
New-onset bronchospasm or recrudescence of asthma associated with cocaine abuse.
Topics: Adult; Aged; Asthma; Bronchial Spasm; Case-Control Studies; Chi-Square Distribution; Cocaine; Comorbidity; Confidence Intervals; Emergency Service, Hospital; Female; Humans; Logistic Models; Male; Middle Aged; New York City; Odds Ratio; Prevalence; Prospective Studies; Recurrence; Substance-Related Disorders; Urban Health | 1997 |
Spectrum of ischemic colitis in cocaine users.
Topics: Adult; Biopsy; Cocaine; Colitis, Ischemic; Colon; Colonoscopy; Crack Cocaine; Female; Humans; Male; Opioid-Related Disorders; Rectum; Recurrence | 1997 |
Treatment outcome of cocaine-alcohol dependent patients.
Topics: Adaptation, Psychological; Alcoholism; Cocaine; Combined Modality Therapy; Comorbidity; Female; Follow-Up Studies; Humans; Male; Mental Disorders; Recurrence; Self Concept; Substance-Related Disorders; Treatment Outcome | 1997 |
A role for sensitization in craving and relapse in cocaine addiction.
Topics: Behavior; Brain; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Humans; Recurrence; Substance-Related Disorders; Synaptic Transmission | 1998 |
Rehabilitation of heroin and cocaine abusers managed in a Nigerian psychiatric hospital.
Topics: Adult; Cocaine; Employment; Female; Follow-Up Studies; Heroin Dependence; Hospitals, Psychiatric; Humans; Male; Nigeria; Program Evaluation; Recurrence; Substance Abuse Treatment Centers; Substance-Related Disorders | 1998 |
The role of corticotropin-releasing factor and corticosterone in stress- and cocaine-induced relapse to cocaine seeking in rats.
Topics: Adrenal Glands; Adrenalectomy; Animals; Catheterization, Peripheral; Cocaine; Corticosterone; Corticotropin-Releasing Hormone; Electroshock; Male; Rats; Recurrence; Reinforcement, Psychology; Self Administration; Stress, Physiological | 1998 |
Prenatal exposure to cocaine and other drugs. Outcome at four to six years.
Topics: Adult; Alcoholism; Child; Child, Preschool; Cocaine; Cognition; Environment; Female; Humans; Intelligence; Longitudinal Studies; Pregnancy; Prenatal Exposure Delayed Effects; Prospective Studies; Psychology, Child; Recurrence; Reference Values; Social Behavior; Socioeconomic Factors; Substance-Related Disorders | 1998 |
Reduced central serotonin transporters in alcoholism.
Topics: Adult; Alcohol Drinking; Alcoholism; Anxiety Disorders; Brain Stem; Carrier Proteins; Cocaine; Depressive Disorder; Dopamine; Dopamine Plasma Membrane Transport Proteins; Ethanol; Humans; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Recurrence; Risk Factors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Substance Withdrawal Syndrome; Tomography, Emission-Computed, Single-Photon | 1998 |
A role for nucleus accumbens glutamate transmission in the relapse to cocaine-seeking behavior.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Local; Animals; Behavior, Addictive; Behavior, Animal; Benzazepines; Cocaine; Cocaine-Related Disorders; Dizocilpine Maleate; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Feeding Behavior; Glutamates; Glutamic Acid; Male; Nucleus Accumbens; Procaine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Recurrence; Self Administration; Synaptic Transmission | 1999 |
Reinstatement of cocaine self-administration in rats: sex differences.
Topics: Analysis of Variance; Animals; Behavior, Animal; Cocaine; Disease Models, Animal; Dose-Response Relationship, Drug; Extinction, Psychological; Female; Infusions, Intravenous; Male; Rats; Rats, Wistar; Recurrence; Self Administration; Sex Factors; Substance-Related Disorders | 2000 |
Dissociation of primary and secondary reward-relevant limbic nuclei in an animal model of relapse.
Topics: Amygdala; Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Infusion Pumps, Implantable; Limbic System; Male; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Recurrence; Reward; Self Administration; Sodium Channels; Tetrodotoxin | 2000 |
Continuous high-dose intracoronary nitroglycerin infusion in refractory coronary vasospasm.
Topics: Adult; Angioplasty, Balloon, Coronary; Cocaine; Cocaine-Related Disorders; Coma; Coronary Vasospasm; Fatal Outcome; Female; Heart Arrest; Humans; Infusions, Intra-Arterial; Nitroglycerin; Recurrence; Stents; Vasodilator Agents | 1999 |
Cocaine vaccines: antibody protection against relapse in a rat model.
Topics: Animals; Antibodies, Monoclonal; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Immunologic; Hemocyanins; Immunization; Immunization, Passive; Male; Rats; Rats, Wistar; Recurrence; Reinforcement, Psychology; Self Administration; Vaccination; Vaccines | 2000 |
Elevated central serotonin transporter binding availability in acutely abstinent cocaine-dependent patients.
Topics: Adult; Age Factors; Brain; Brain Stem; Carrier Proteins; Cocaine; Cocaine-Related Disorders; Diencephalon; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Recurrence; Risk Factors; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Tomography, Emission-Computed, Single-Photon; Treatment Outcome | 2000 |
Glutamate transmission in the nucleus accumbens mediates relapse in cocaine addiction.
Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Extinction, Psychological; Glutamic Acid; Male; Microinjections; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Dopamine; Receptors, N-Methyl-D-Aspartate; Recurrence; Self Administration; Synaptic Transmission | 2000 |
Relapse to cocaine-seeking after hippocampal theta burst stimulation.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dopamine; Electric Stimulation; Electrodes; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extinction, Psychological; Glutamic Acid; Hippocampus; Injections, Intravenous; Kynurenic Acid; Medial Forebrain Bundle; Memory; N-Methylaspartate; Rats; Rats, Long-Evans; Recurrence; Reward; Self Administration; Synaptic Transmission; Theta Rhythm; Ventral Tegmental Area | 2001 |
Dopamine, but not glutamate, receptor blockade in the basolateral amygdala attenuates conditioned reward in a rat model of relapse to cocaine-seeking behavior.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amygdala; Animals; Behavior, Addictive; Benzazepines; Cocaine; Conditioning, Operant; Dopamine Antagonists; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Extinction, Psychological; Male; Motor Activity; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Recurrence; Reward; Self Administration | 2001 |
Drug addiction. Zapping memory center triggers drug craving.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dopamine; Electric Stimulation; Extinction, Psychological; Glutamic Acid; Hippocampus; Injections, Intravenous; Medial Forebrain Bundle; Memory; Rats; Recurrence; Reward; Self Administration; Ventral Tegmental Area | 2001 |
Differential contributions of the basolateral and central amygdala in the acquisition and expression of conditioned relapse to cocaine-seeking behavior.
Topics: Amygdala; Animals; Association Learning; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Classical; Male; Rats; Rats, Sprague-Dawley; Recurrence; Reinforcement, Psychology; Self Administration; Sodium Channel Blockers; Tetrodotoxin | 2001 |
Drug-induced reinstatement to heroin and cocaine seeking: a rodent model of relapse in polydrug use.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Extinction, Psychological; Heroin; Heroin Dependence; Infusions, Intravenous; Male; Narcotics; Rats; Rats, Long-Evans; Recurrence; Self Administration | 2001 |
A cannabinoid mechanism in relapse to cocaine seeking.
Topics: Animals; Behavior, Animal; Cannabinoid Receptor Modulators; Cannabinoids; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dronabinol; Humans; Piperidines; Pyrazoles; Rats; Rats, Long-Evans; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug; Recurrence; Rimonabant | 2001 |
The circuitry mediating cocaine-induced reinstatement of drug-seeking behavior.
Topics: Animals; Behavior, Animal; Chronic Disease; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine; GABA Agonists; GABA-A Receptor Agonists; GABA-B Receptor Agonists; Globus Pallidus; Injections, Intraperitoneal; Male; Microinjections; Motor Activity; Nerve Net; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Recurrence; Reinforcement, Psychology; Self Administration; Ventral Tegmental Area | 2001 |
A role for the CRF-containing pathway from central nucleus of the amygdala to bed nucleus of the stria terminalis in the stress-induced reinstatement of cocaine seeking in rats.
Topics: Amygdala; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Corticotropin-Releasing Hormone; Extinction, Psychological; Functional Laterality; Male; Neural Pathways; Rats; Rats, Long-Evans; Recurrence; Self Administration; Septal Nuclei; Stress, Physiological; Tetrodotoxin | 2001 |
Cocaine administered into the medial prefrontal cortex reinstates cocaine-seeking behavior by increasing AMPA receptor-mediated glutamate transmission in the nucleus accumbens.
Topics: Anesthetics, Local; Animals; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Extinction, Psychological; Glutamic Acid; Male; Microinjections; Neostriatum; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Recurrence; Reinforcement, Psychology; Septum of Brain; Synaptic Transmission | 2002 |
Influence of cue-conditioning on acquisition, maintenance and relapse of cocaine intravenous self-administration.
Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Cues; Dose-Response Relationship, Drug; Extinction, Psychological; Injections, Intravenous; Male; Photic Stimulation; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration | 2002 |
Blockade of stress-induced but not cocaine-induced reinstatement by infusion of noradrenergic antagonists into the bed nucleus of the stria terminalis or the central nucleus of the amygdala.
Topics: Adrenergic beta-Antagonists; Amygdala; Animals; Betaxolol; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Extinction, Psychological; Infusions, Parenteral; Norepinephrine; Propanolamines; Rats; Rats, Long-Evans; Recurrence; Self Administration; Septal Nuclei; Stress, Physiological; Sucrose | 2002 |
Intermittent Horner's syndrome: recurrent, alternate Horner's syndrome in cervical cord injury.
Topics: Cocaine; Epinephrine; Horner Syndrome; Humans; Neck; Posture; Recurrence; Spinal Cord Injuries; Time Factors | 1975 |
One-year follow-up after multimodal inpatient treatment for cocaine and methamphetamine dependencies.
Topics: Adult; Aftercare; Alcoholism; Aversive Therapy; Cocaine; Combined Modality Therapy; Female; Follow-Up Studies; Hospitalization; Humans; Male; Marijuana Abuse; Methamphetamine; Recurrence; Substance Abuse Treatment Centers; Substance-Related Disorders | 1992 |
Severity of cocaine dependence as a predictor of relapse to cocaine use.
Topics: Analysis of Variance; Chi-Square Distribution; Cocaine; Female; Follow-Up Studies; Hospitalization; Humans; Male; Probability; Psychiatric Status Rating Scales; Recurrence; Severity of Illness Index; Substance-Related Disorders | 1992 |
A learning model of addiction.
Topics: Affect; Arousal; Cocaine; Combined Modality Therapy; Conditioning, Classical; Humans; Motivation; Recurrence; Reinforcement, Psychology; Substance Withdrawal Syndrome; Substance-Related Disorders | 1992 |
Recidivism among high risk youths: a 2 1/2-year follow-up of a cohort of juvenile detainees.
Topics: Adolescent; Alcoholism; Child Abuse; Child Abuse, Sexual; Cocaine; Cohort Studies; Female; Follow-Up Studies; Humans; Illicit Drugs; Juvenile Delinquency; Male; Personality Assessment; Prisons; Prospective Studies; Recurrence; Risk Factors; Substance-Related Disorders | 1991 |
Cocaine and scleroderma: is there an association?
Topics: Adult; Cocaine; Humans; Male; Recurrence; Scleroderma, Systemic; Substance-Related Disorders | 1991 |
Psychological approaches for the treatment of cocaine dependence--a neurobehavioral approach.
Topics: Adult; Ambulatory Care; Cocaine; Female; Humans; Male; Models, Psychological; Program Evaluation; Psychotherapy; Recurrence; Substance-Related Disorders | 1991 |
Relapse to cocaine use following treatment: preliminary findings on the role of social support.
Topics: Adult; Cocaine; Female; Humans; Male; Recurrence; Risk; Sex Factors; Social Support; Substance-Related Disorders | 1990 |
Cocaine heart disease.
Topics: Cocaine; Coronary Disease; Heart; Heart Diseases; Humans; Myocardial Infarction; Recurrence; Substance-Related Disorders | 1991 |
Effects of commitment to abstinence, positive moods, stress, and coping on relapse to cocaine use.
Topics: Adult; Affect; Cocaine; Female; Humans; Male; Prognosis; Prospective Studies; Recurrence; Retrospective Studies; Stress, Psychological; Substance-Related Disorders | 1991 |
Recurrent embolic stroke and cocaine-related cardiomyopathy.
Topics: Adult; Cardiomyopathy, Dilated; Cerebral Infarction; Cerebrovascular Disorders; Cocaine; Echocardiography; Humans; Intracranial Embolism and Thrombosis; Male; Recurrence; Substance-Related Disorders; Tomography, X-Ray Computed | 1991 |
Relapse prevention strategies for the treatment of cocaine abuse.
Topics: Adaptation, Psychological; Adolescent; Adult; Ambulatory Care; Cocaine; Cognitive Behavioral Therapy; Cues; Female; Follow-Up Studies; Humans; Internal-External Control; Life Style; Male; Personality Assessment; Recurrence; Self Concept; Social Facilitation; Substance-Related Disorders | 1991 |
Cocaine use in arrestees: refining measures of national trends by sampling the criminal population.
Topics: Cocaine; Crack Cocaine; Crime; District of Columbia; Female; Humans; Male; Recurrence; Substance-Related Disorders; United States | 1991 |
Recurrent rhabdomyolysis in association with cocaine use.
Topics: Acute Kidney Injury; Adult; Cocaine; Humans; Male; Recurrence; Rhabdomyolysis; Substance Abuse, Intravenous | 1991 |
Cocaine-associated chest pain.
Topics: Adolescent; Adult; Chest Pain; Cocaine; Coronary Care Units; Diagnosis, Differential; Electrocardiography; Emergency Service, Hospital; Female; Hospitals, County; Hospitals, Urban; Humans; Incidence; Male; Middle Aged; Myocardial Infarction; Patient Admission; Physical Examination; Recurrence; Retrospective Studies; Sensitivity and Specificity; Substance-Related Disorders; Time Factors | 1991 |
Death by embolization of prosthetic aortic valve.
Topics: Adult; Animals; Bioprosthesis; Cocaine; Embolism; Endocarditis, Bacterial; Female; Heart Valve Prosthesis; Humans; Recurrence; Streptococcal Infections; Substance Abuse, Intravenous | 1991 |
Cocaine in pregnancy: confronting the problem.
Topics: Cocaine; Female; Forensic Medicine; Hospitals, University; Humans; Patient Education as Topic; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Recurrence; Risk Factors; South Carolina; Substance-Related Disorders | 1990 |
Cocaine-associated multifocal tics.
Topics: Adult; Cocaine; Female; Humans; Male; Recurrence; Tic Disorders; Tourette Syndrome | 1990 |
Relapse prevention in psychoeducational groups for compulsive crack cocaine smokers.
Topics: Cocaine; Health Education; Humans; Psychotherapy, Group; Recurrence; Risk Factors; Substance-Related Disorders | 1989 |
A laboratory procedure for evaluation of pharmacotherapy for cocaine dependence.
Topics: Adult; Arousal; Bromocriptine; Cocaine; Cues; Humans; Male; Recurrence; Substance-Related Disorders | 1989 |
Cocaine, pulmonary hemorrhage, and hemoptysis.
Topics: Administration, Inhalation; Adult; Cocaine; Female; Hemoptysis; Hemorrhage; Humans; Lung Diseases; Recurrence | 1989 |
Psychological and environmental determinants of relapse in crack cocaine smokers.
Topics: Adult; Cocaine; Female; Humans; Interpersonal Relations; Male; Recurrence; Risk Factors; Social Environment; Social Isolation; Social Support; Substance-Related Disorders | 1989 |
Experience with the cocaine trigger inventory.
Topics: Cocaine; Cues; Humans; Psychological Tests; Recurrence; Social Environment; Social Facilitation; Substance-Related Disorders | 1989 |
Characteristics of relapse following adolescent substance abuse treatment.
Topics: Adaptation, Psychological; Adolescent; Alcoholism; Cocaine; Female; Follow-Up Studies; Humans; Male; Marijuana Abuse; Psychiatric Department, Hospital; Recurrence; Risk Factors; Social Environment; Substance-Related Disorders | 1989 |
[Drug dependence].
Topics: Amphetamines; Cocaine; Hallucinogens; Humans; Marijuana Abuse; Morphine Dependence; Opioid-Related Disorders; Recurrence; Solvents; Substance-Related Disorders; USSR | 1989 |
Relapse to use of heroin, cocaine, and other drugs in the first year after treatment.
Topics: Alcoholism; Cocaine; Heroin Dependence; Humans; Marijuana Abuse; Prognosis; Prospective Studies; Recurrence; Substance-Related Disorders | 1986 |
Classically conditioned responses in opioid and cocaine dependence: a role in relapse?
Topics: Cocaine; Conditioning, Classical; Humans; Methadone; Opioid-Related Disorders; Random Allocation; Recurrence; Substance-Related Disorders | 1988 |
Differences in psychological needs among drug abusers: first admissions compared to recidivists.
Topics: Adult; Cocaine; Humans; Male; Opioid-Related Disorders; Patient Readmission; Psychological Tests; Recurrence; Substance-Related Disorders | 1988 |
Relapse to cocaine abuse after initiating desipramine treatment.
Topics: Adult; Bulimia; Cocaine; Depressive Disorder; Desipramine; Female; Humans; Male; Recurrence; Substance-Related Disorders; Syndrome; Temperance; Time Factors | 1988 |
Breaking the cycle of addiction.
Topics: Behavior Therapy; Cocaine; Desipramine; Humans; Mental Disorders; Psychotherapy; Recurrence; Substance Withdrawal Syndrome; Substance-Related Disorders | 1988 |
Recurrent myocardial infarction associated with cocaine abuse in a young man with normal coronary arteries: evidence for coronary artery spasm culminating in thrombosis.
Topics: Adult; Cardiac Catheterization; Cocaine; Coronary Angiography; Coronary Artery Bypass; Coronary Vasospasm; Electrocardiography; Humans; Male; Myocardial Infarction; Recurrence; Substance-Related Disorders | 1987 |
Social network therapy for cocaine dependence.
Topics: Cocaine; Confidentiality; Family Therapy; Humans; Patient Compliance; Recurrence; Social Environment; Social Support; Substance-Related Disorders | 1986 |
Cocaine and MI.
Topics: Adult; Cocaine; Humans; Male; Myocardial Infarction; Recurrence; Substance-Related Disorders | 1987 |
Dilated cardiomyopathy and cocaine abuse. Report of two cases.
Topics: Adult; Cardiomyopathy, Dilated; Cocaine; Female; Humans; Male; Recurrence; Substance-Related Disorders | 1986 |
Nonpharmacologic treatment of cocaine abuse.
Topics: Cocaine; Conditioning, Psychological; Goals; Humans; Life Style; Mental Disorders; Patient Acceptance of Health Care; Patient Care Planning; Psychotherapy; Recurrence; Risk; Substance-Related Disorders | 1986 |
Recurrent myocardial infarction caused by cocaine abuse.
Topics: Adult; Cocaine; Humans; Male; Myocardial Infarction; Recurrence; Substance-Related Disorders | 1986 |
Opiate and cocaine dependencies. Techniques to help counter the rising tide.
Topics: Ambulatory Care; Blood Pressure; Clonidine; Cocaine; Drug Tolerance; Hospitalization; Humans; Opioid-Related Disorders; Recurrence; Substance Withdrawal Syndrome; Substance-Related Disorders | 1985 |
Interpersonal psychotherapy adapted for ambulatory cocaine abusers.
Topics: Adult; Cocaine; Grief; Humans; Impulsive Behavior; Interpersonal Relations; Male; Marriage; Psychotherapy; Recurrence; Substance-Related Disorders | 1985 |
Conservative surgery in the treatment of nasal polypi.
Topics: Anesthesia, General; Betamethasone; Cocaine; Epinephrine; Ethmoid Sinus; Histamine H1 Antagonists; Humans; Nasal Mucosa; Nasal Polyps; Postoperative Care; Postoperative Complications; Recurrence; Surgical Instruments | 1973 |
Patterns of multiple drug abuse: 1969-1971.
Topics: Adolescent; Adult; Age Factors; Amphetamine; Barbiturates; Black or African American; Cannabis; Cocaine; Educational Status; Female; Hallucinogens; Heroin; Humans; Male; Marriage; Mexico; Puerto Rico; Recurrence; Religion; Solvents; Substance-Related Disorders; Time Factors; United States | 1974 |
Recent developments in the therapy of addictions.
Topics: Amphetamine; Aversive Therapy; Barbiturates; Cocaine; Hallucinogens; Humans; Methadone; Nicotiana; Opium; Plants, Toxic; Recurrence; Substance-Related Disorders | 1972 |
Crack cocaine and dreams: the view of users.
Topics: Adult; Cocaine-Related Disorders; Crack Cocaine; Craving; Dreams; Female; Humans; Male; Middle Aged; Recurrence | 2019 |
Levamisole-induced vasculopathy: staging and management.
Topics: Adult; Crack Cocaine; Drug Contamination; Female; Humans; Levamisole; Necrosis; Purpura; Recurrence; Severity of Illness Index; Skin; Vasculitis | 2014 |
Social and clinical predictors of drug-resistant tuberculosis in a public hospital, Monterrey, Mexico.
Topics: Adult; Case-Control Studies; Cocaine-Related Disorders; Comorbidity; Crack Cocaine; DNA; Female; Genetic Markers; Hospitals, Urban; Humans; Interviews as Topic; Logistic Models; Male; Medical Records; Mexico; Middle Aged; Mycobacterium; Recurrence; Risk Factors; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2014 |
Rural drug users: factors associated with substance abuse treatment utilization.
Topics: Adolescent; Adult; Alcoholism; Amphetamine-Related Disorders; Arkansas; Cocaine-Related Disorders; Comorbidity; Crack Cocaine; Female; Health Services Research; Humans; Illicit Drugs; Kentucky; Male; Methamphetamine; Middle Aged; Ohio; Patient Acceptance of Health Care; Patient Readmission; Recurrence; Retrospective Studies; Rural Population; Substance Abuse Treatment Centers; Substance-Related Disorders; Young Adult | 2011 |
Occlusive vasculopathy with vascular and skin necrosis secondary to smoking crack cocaine.
Topics: Adult; Cocaine-Related Disorders; Crack Cocaine; Female; Humans; Purpura; Recurrence; Skin; Vascular Diseases | 2011 |
Predictors of alcohol and crack cocaine use outcomes over a 3-year follow-up in treatment seekers.
Topics: Adult; Alcoholism; Cocaine-Related Disorders; Convalescence; Crack Cocaine; Female; Follow-Up Studies; Humans; Male; Recurrence; Time Factors | 2005 |
Recurrent metabolic alkalosis and elevated troponins after crack cocaine use in a hemodialysis patient.
Topics: Acidosis; Adult; Cocaine-Related Disorders; Crack Cocaine; Humans; Male; Pulmonary Edema; Recurrence; Renal Dialysis; Sodium Hydroxide; Troponin I | 2006 |
[Hemoptysis in a young man].
Topics: Adult; Biopsy; Crack Cocaine; Hemoptysis; Humans; Male; Pulmonary Alveoli; Recurrence; Thoracoscopy; Video Recording | 2006 |
Identifying injection drug users at risk of nonfatal overdose.
Topics: Adolescent; Adult; Cocaine-Related Disorders; Crack Cocaine; Cross-Sectional Studies; Drug Overdose; Female; Heroin Dependence; Humans; Male; Middle Aged; Recurrence; Risk Assessment; Risk Factors; Substance Abuse Detection; Substance Abuse, Intravenous; United States | 2007 |
Outcomes of cocaine-induced gastric perforations repaired with an omental patch.
Topics: Cocaine-Related Disorders; Crack Cocaine; Female; Humans; Male; Middle Aged; Omentum; Peptic Ulcer Perforation; Recurrence; Retrospective Studies; Treatment Outcome | 2007 |
Multiple cocaine-induced seizures and corresponding cocaine and metabolite concentrations.
Topics: Adult; Crack Cocaine; Diagnosis, Differential; Emergency Treatment; Humans; Male; Recurrence; Seizures; Substance-Related Disorders | 1998 |
Working with relapse.
Topics: Adult; Cocaine-Related Disorders; Crack Cocaine; Female; Heart Failure; Humans; Patient Readmission; Recurrence; Risk Factors; Single Parent | 1999 |
Changes in use of crack cocaine after drug misuse treatment: 4-5 year follow-up results from the National Treatment Outcome Research Study (NTORS).
Topics: Chi-Square Distribution; Cocaine-Related Disorders; Crack Cocaine; England; Follow-Up Studies; Humans; Logistic Models; Longitudinal Studies; Recurrence; Substance Abuse Treatment Centers; Treatment Outcome | 2002 |
A common profile of prefrontal cortical activation following exposure to nicotine- or chocolate-associated contextual cues.
Topics: Animals; Behavior, Animal; Cacao; Candy; Cell Count; Conditioning, Psychological; Cues; Learning; Male; Motor Activity; Neural Pathways; Neuronal Plasticity; Neurons; Nicotine; Prefrontal Cortex; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Recurrence; Reward; Tobacco Use Disorder | 2001 |
Effect of Climatic Parameters on Acute Urinary Retention Incidence.
Topics: Acute Disease; Adult; Age Factors; Aged; Follow-Up Studies; Humans; Humidity; Incidence; Male; Middle Aged; Prostate-Specific Antigen; Prostatic Hyperplasia; Recurrence; Republic of Korea; Risk Factors; Seasons; Snow; Sunlight; Temperature; Urinary Retention; Weather; Wind | 2018 |
Dyschromatopsia following cataract surgery.
Topics: Aged; Aphakia, Postcataract; Cataract Extraction; Color Vision Defects; Diuretics; Humans; Hydrochlorothiazide; Lenses, Intraocular; Male; Middle Aged; Migraine Disorders; Postoperative Complications; Recurrence; Snow; Sunlight; Time Factors | 1986 |