cocaine has been researched along with Parkinson Disease in 182 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (3.85) | 18.7374 |
| 1990's | 57 (31.32) | 18.2507 |
| 2000's | 82 (45.05) | 29.6817 |
| 2010's | 29 (15.93) | 24.3611 |
| 2020's | 7 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Alessi, SM; Barbosa, DAN; Bentzley, BS; Halpern, CH; Kampman, KM; Ku, S; Kuijper, FM; Mahajan, UV; Stein, SC | 1 |
| Algar, S; Ballesteros, JA; Benhamú, B; Brea, J; Cincilla, G; García-Cárceles, J; Ladron de Guevara-Miranda, D; López-Rodríguez, ML; Loza, MI; Roberts, RS; Rodríguez de Fonseca, F; Sánchez-Martínez, M; Sánchez-Merino, A; Teresa de Los Frailes, M; Vázquez-Villa, H | 1 |
| Han, XM; Li, YP; Liu, BP; Wang, RF; Wang, Z; Xu, SS; Zhang, HY | 1 |
| Ha, ZY; Mathew, S; Yeong, KY | 1 |
| Barbon, A; Bellucci, A; Benfenati, F; Bono, F; Bruno, A; Casiraghi, A; Costantino, G; Faustini, G; Grigoletto, J; La Via, L; Longhena, F; Missale, C; Pizzi, M; Spillantini, MG; Straniero, V; Valoti, E | 1 |
| Li, X; Li, Y; Mutaerbieke, N; Qin, Y; Yibulayin, A; Zhang, Q; Zhao, X | 1 |
| Correa, M; Fuertes-Saiz, A; Haro, G; Pérez-Saldaña, MT; Salais, L; Salamone, J | 1 |
| Potashkin, JA; Santiago, JA | 1 |
| Mukai, Y; Murata, M; Takahashi, Y | 1 |
| Clement, N; Frosch, M; Gomez-Isla, T; Gomperts, SN; Growdon, JH; Johnson, KA; Katz, S; Schultz, A; Shirvan, J; Ye, R | 1 |
| Bagnoli, J; Consiglio, L; Difazio, P; Giorelli, M; Lopane, M; Zimatore, GB; Zizza, D | 1 |
| Agnati, LF; Borroto-Escuela, DO; Ciruela, F; Fuxe, K; Palkovits, M; Romero-Fernandez, W; Tarakanov, AO | 1 |
| Gong, X; Liang, X; Liu, L; Wang, X; Zhang, W | 1 |
| Eberly, S; Jennings, D; Marek, K; Oakes, D; Seibyl, J; Shoulson, I | 1 |
| Eberly, S; Jennings, D; Marek, K; Oakes, D; Seibyl, J; Siderowf, A; Stern, M | 1 |
| Ehm, G; Jeon, BS; Kim, HJ; Kim, YE; Yang, HJ; Yun, JY | 1 |
| Bellucci, A; Benfenati, F; Castrezzati, S; Colivicchi, MA; Della Corte, L; Favero, G; Grigoletto, J; Longhena, F; Missale, C; Navarria, L; Pizzi, M; Rezzani, R; Spano, P; Spillantini, MG; Zaltieri, M | 1 |
| Chahine, LM; Eberly, S; Hawkins, KA; Jennings, D; Marek, K; Oakes, D; Seibyl, J; Siderowf, A; Stern, MB; Weintraub, D | 1 |
| Ding, ZT; Ge, JJ; Huang, SF; Liu, SY; Wang, J; Wang, YX; Wu, JJ; Wu, P; Zhao, J; Zuo, CT | 1 |
| Bayer, S; Gomperts, SN; Growdon, JH; Johnson, KA; Locascio, JJ; Marquie, M | 1 |
| Chen, T; Chen, Y; Guo, Z; Wang, R; Xu, B; Zhang, J; Zhu, H | 1 |
| Bohnen, NI; Constantine, GM; Gedela, S; Herath, P; Moore, RY | 1 |
| Iida, A; Inoue, N; Kakiuchi, T; Kondo, Y; Muramatsu, S; Nakano, I; Nakayama, T; Okuno, T; Ono, F; Suzuki, Y; Takino, N; Terao, K; Tsukada, H | 1 |
| Gai, Y; Guo, LH; Jiang, ZH; Qin, GW; Zhao, G; Zheng, XW | 1 |
| Classen, J; Lorenz, R; Reiners, K; Schirbel, A; Schliesser, M; Weise, D | 1 |
| Farrer, MJ; Hattori, N; Imai, H; Inoue, Y; Ishii, K; Ishiwata, K; Kachergus, JM; Kitagawa, M; Kono, S; Mizoguchi, K; Mizuno, Y; Nishioka, K; Obi, T; Ross, OA; Takanashi, M | 1 |
| Cui, XX; Guo, JF; Jiang, H; Lei, LF; Long, ZG; Pan, Q; Shen, L; Song, XW; Tang, BS; Wang, JL; Xia, K; Xiao, B; Yan, XX | 1 |
| Gold, MS; Graham, NA; Hammond, CJ | 1 |
| Nocker, M; Scherfler, C | 1 |
| Ouchi, Y; Sakamoto, M; Yagi, S; Yokokura, M | 1 |
| Berendse, HW; Ponsen, MM | 1 |
| Fasano, A; Petrovic, I | 1 |
| Futatsubashi, M; Ouchi, Y; Torizuka, T; Yagi, S; Yokokura, M; Yoshihara, Y; Yoshikawa, E | 1 |
| Donnemiller, E; Goebel, G; Poewe, W; Scherfler, C; Seppi, K; Virgolini, I; Warwitz, B; Wenning, GK | 1 |
| Gartenschlaeger, M; Kramer, K; Schreckenberger, M; Vogt, T | 1 |
| Doering, LC; Farncombe, TH; Gleave, JA; Saab, C | 1 |
| Alstrup, AK; Doudet, DJ; Gjedde, A; Høltzermann, M; Jakobsen, S; Landau, AM; Møller, A; Nahimi, A; Simonsen, M; Vang, K; Wegener, G | 1 |
| Donnemiller, E; Nocker, M; Poewe, W; Scherfler, C; Seppi, K; Virgolini, I; Wenning, GK | 1 |
| Huang, T; Liang, X; Shi, X; Tang, G; Wang, H; Zhang, X | 1 |
| Ascherio, A; Beal, F; Beck, J; Eberly, S; Flagg, E; Galpern, WR; Harman, J; Kurlan, R; Lang, AE; Marek, K; Oakes, D; Ravina, B; Schwarzschild, M; Shoulson, I; Tanner, C | 1 |
| Donnemiller, E; Mair, KJ; Poewe, W; Scherfler, C; Seppi, K; Virgolini, I; Wenning, GK | 1 |
| Liu, S; Shen, L; Tian, ZM; Wang, RM; Wieman, J; Yan, Y; Yin, F; Zhao, QJ | 1 |
| Crossman, AR; Kobylecki, C; Ravenscroft, P | 1 |
| Asenbaum, S; Bencsits, G; Bloem, BR; Brücke, T; Gerschlager, W; Hoffmann, M; Pirker, W; Prayer, D; Zijlmans, JC | 1 |
| Chung, HK; Jeon, B; Kim, HK; Kim, JM; Kim, JW; Kim, Y; Lee, CR; Lee, DS; Lee, JH; Yang, SO; Yoo, CI | 1 |
| Ahlskog, JE; Maraganore, DM; Uhl, GR; Uitti, RJ | 1 |
| Chen, JC; Hwang, JJ; Liao, MH; Lin, KJ; Pan, WH; Ting, G; Wey, SP; Yen, TC | 1 |
| Jennings, D; Marek, K; Seibyl, J | 1 |
| Friberg, L; Løkkegaard, A; Werdelin, LM | 1 |
| Cattabeni, F | 1 |
| Happe, S; Klösch, G; Pirker, W; Sauter, C; Zeitlhofer, J | 1 |
| Snow, B | 1 |
| Bergmans, P; Booij, J; Stoof, JC; van Royen, EA; Winogrodzka, A; Wolters, EC | 1 |
| Berding, G; Brooks, DJ; Brücke, T; Dengler, R; Gielow, P; Harke, H; Knapp, WH; Knoop, BO; Kolbe, H; Odin, P | 1 |
| Amano, T; Fukuuchi, Y; Hashimoto, J; Itoh, Y; Kubo, A; Muramatsu, K; Sasaki, T | 1 |
| Seibyl, JP | 1 |
| Choe, YS; Choi, JY; Choi, Y; Kim, SE; Lee, WY | 1 |
| Auff, E; Dirnberger, G; Gerschlager, W; Holler, I; Pirker, W | 1 |
| Pirker, W | 1 |
| Brooks, DJ; Frey, KA; Marek, KL; Oakes, D; Paty, D; Prentice, R; Shults, CW; Stoessl, AJ | 1 |
| Itti, E; Malek, Z; Rémy, P | 1 |
| Asenbaum, S; Brücke, T; Gerschlager, W; Holler, I; Pirker, W; Zettinig, G | 1 |
| Grosset, D; Marshall, V | 1 |
| Ding, H; He, L; Kuang, A; Ye, B; Yuan, Q; Zheng, H | 1 |
| Barthel, H; Hesse, S; Sabri, O | 1 |
| Berendse, HW; Booij, J; Ponsen, MM; Stoffers, D; van Eck-Smit, BL; Wolters, ECh | 1 |
| Boesch, SM; Donnemiller, E; Müller, J; Poewe, W; Seppi, K; Weirich-Schwaiger, H; Wenning, GK | 1 |
| Burn, DJ; Colloby, SJ; Fenwick, JD; Firbank, MJ; McKeith, IG; O'Brien, JT; Williams, ED | 1 |
| Karlsborg, M; Knudsen, GM; Krabbe, K; Nygaard, T; Regeur, L; Thomsen, G; Videbaek, C; Werdelin, L | 1 |
| Anderer, P; Gruber, G; Happe, S; Klösch, G; Pirker, W; Saletu, B; Zeitlhofer, J | 1 |
| Ahlskog, JE; Albin, RL; Brooks, DJ; Carbon, M; Dhawan, V; Eidelberg, D; Fahn, S; Feigin, A; Guttman, M; Gwinn-Hardy, K; Holloway, R; Innis, R; Katz, RG; Kieburtz, K; Kish, SJ; Lange, N; Langston, JW; Marek, K; McFarland, H; Morin, L; Moy, C; Murphy, D; Oertel, WH; Oliver, G; Palesch, Y; Powers, W; Ravina, B; Seibyl, J; Sethi, KD; Sheehy, P; Shults, CW; Stoessl, AJ | 1 |
| Berendse, HW; Booij, J; Bosscher, L; Stoffers, D; Winogrodzka, A; Wolters, EC | 1 |
| Hosokawa, R; Kawamura, T; Miyamoto, K; Ohba, M; Sawada, H; Shimohama, S; Yamakado, H; Yamakawa, K | 1 |
| Brenneis, C; Donnemiller, E; Goebel, G; Poewe, W; Scherfler, C; Seppi, K; Virgolini, I; Wenning, GK | 1 |
| Broussolle, E; Remy, P; Thobois, S | 1 |
| Morgan, J; Sethi, KD | 1 |
| Eerola, J; Kaakkola, S; Launes, J; Nikkinen, P; Tienari, PJ | 1 |
| Fazio, F; Garibotto, V; Hadjigeorgiou, GM; Papadimitriou, A; Papadimitriou, D; Perani, D | 1 |
| Bhidayasiri, R | 1 |
| Deleu, D; Hanssens, Y | 1 |
| Andren, PE; Svenningsson, P; Zhang, X | 1 |
| Di Rocco, A; Nasser, S; Werner, P | 1 |
| Hattori, N; Ida, H; Kono, S; Miyajima, H; Mizuno, Y; Ouchi, Y; Sakamoto, M; Shirakawa, K; Sugiura, T; Suzuki, H; Takahashi, Y; Tomiyama, H | 1 |
| Early, M; Jennings, D; Marek, K; Seibyl, JP; Yuan, O; Zubal, IG | 1 |
| Bohnen, NI; Constantine, GM; Gedela, S; Kuwabara, H; Mathis, CA; Moore, RY; Studenski, SA | 1 |
| Cepeda, IL; Cornfeldt, ML; Doudet, DJ; Flores, J; O'Kusky, JR | 1 |
| Bohnen, NI; Constantine, GM; Kuwabara, H; Mathis, CA; Moore, RY | 1 |
| Baekelandt, V; Bormans, G; Casteels, C; Lauwers, E; Van Laere, K | 1 |
| Choi, YJ; Hong, S; Jeon, BS; Kim, GP; Kim, JM; Kim, SE; Kim, YK; Park, SS | 1 |
| Antonini, A; Booij, J; Caretti, V; Costantino, G; Ferrarese, C; Isaias, IU; Pezzoli, G; Stoffers, D; Winogrodzka, A; Wolters, EC | 1 |
| Andren, PE; Chergui, K; Svenningsson, P; Zhang, X | 1 |
| Agid, Y; Javoy-Agid, F; Langer, SZ; Pimoule, C; Scatton, B; Schoemaker, H | 1 |
| Baldwin, RM; Charney, DS; Fussell, B; Marek, KL; Quinlan, D; Seibyl, JP; Sheff, K; Smith, EO; van Dyck, C; Zea-Ponce, Y; Zoghbi, S | 1 |
| Bergström, KA; Hakola, P; Hartikainen, P; Karhu, J; Kuikka, JT; Länsimies, E; Lehtonen, J; Tiihonen, J; Viinamäki, H | 1 |
| Laihinen, AO; Lehikoinen, PK; Någren, KA; Oikonen, VJ; Rinne, JO; Rinne, UK; Ruotsalainen, UH; Ruottinen, HM | 1 |
| Silverman, PB | 1 |
| Innis, RB | 2 |
| Angelberger, P; Asenbaum, S; Brücke, T; Frassine, H; Kornhuber, J; Podreka, I | 1 |
| Madras, BK | 1 |
| Isacson, O | 1 |
| Bergström, KA; Hartikainen, P; Kuikka, JT; Länsimies, E; Laulumaa, V; Vanninen, E | 1 |
| Abi-Dargham, A; Baldwin, RM; Innis, RB; Laruelle, M; Scanley, BE; Seibyl, JP; Wallace, E; Wang, S; Zea-Ponce, Y; Zoghbi, S | 1 |
| Dannals, RF; Ehlers, MD; Frost, JJ; Ravert, HT; Reich, SG; Rosier, AJ; Smith, JS; Snyder, SH | 1 |
| Laihinen, A; Någren, K; Rinne, JO; Rinne, UK; Ruotsalainen, U; Ruottinen, H | 1 |
| Babchyck, B; Chaly, T; Dhawan, V; Eidelberg, D; Ishikawa, T; Kazumata, K; Mandel, F; Margouleff, C; Neumeyer, J; Zanzi, I | 1 |
| Byon, C; Elmaleh, DR; Fischman, AJ; Hanson, RN; Liang, AY; Madras, BK; Meltzer, PC; Shoup, TM | 1 |
| Angelberger, P; Asenbaum, S; Brücke, T; Deecke, L; Müller, C; Pirker, W; Podreka, I; Wenger, S; Wöber, C | 1 |
| Babich, JW; Barrow, SA; Elmaleh, DR; Fischman, AJ; Hanson, RN; Madras, BK; Meltzer, P | 1 |
| Coenen, HH; Dutschka, K; Farahati, J; Geworski, L; Müller, SP; Reiners, C | 1 |
| Booij, J; Habraken, J; Janssen, AG; Sokole-Busemann, E; Stoof, JC; Tissingh, G; Van Royen, EA; Vermeulen, RJ; Wolters, EC | 1 |
| Domingo, P; Martínez, E | 1 |
| Boer, GJ; Booij, J; Stoof, JC; Tissingh, G; van Royen, EA; Winogrodzka, A; Wolters, EC | 1 |
| Hondl, N; Ladurner, G; Staffen, W; Trinka, E; Zenzmaier, R | 1 |
| Booij, J; Tissingh, G; van Royen, EA; Winogrodzka, A; Wolters, EC | 1 |
| Asenbaum, S; Brücke, T; Djamshidian, S; Müller, C; Pirker, W; Podreka, I; Wenger, S; Wöber, C | 1 |
| Berger, W; Decristoforo, C; Donnemiller, E; Heilmann, J; Moncayo, R; Poewe, W; Ransmayr, G; Wenning, GK | 1 |
| Bergmans, P; Booij, J; Stoof, JC; Tissingh, G; Van Royen, EA; Winogrodzka, A; Wolters, EC | 3 |
| Mellgren, SI; Sjøholm, H; Sundsfjord, J | 1 |
| Baldwin, RM; Charney, DS; Hoffer, PB; Innis, RB; Marek, K; Seibyl, JP; Sheff, K; van Dyck, CH; Zea-Ponce, Y; Zoghbi, S | 1 |
| Ding, YS; Fowler, JS; Gatley, SJ; Volkow, ND; Wang, GJ | 1 |
| Caron, MG; Giros, B; Jaber, M; Jones, S | 1 |
| Coenen, HH; Eising, EG; Farahati, J; Kuhn, W; Müller, TT; Reiners, C; Zander, C | 1 |
| Borrelli, E; Chambon, P; Dupé, V; Ghyselinck, N; Kastner, P; Krezel, W; Samad, TA | 1 |
| Coenen, HH; Eising, EG; Farahati, J; Kuhn, W; Müller, T; Przuntek, H; Reiners, C | 1 |
| Babich, J; Elmaleh, D; Fahey, MA; Fischman, AJ; Gracz, LM; Liang, AY; Madras, BK; Meltzer, PC; Stopa, EG | 1 |
| Alpert, NM; Babich, JW; Barrow, SA; Bonab, AA; Callahan, RJ; Elmaleh, DR; Fischman, AJ; Graham, W; Hanson, RN; Madras, BK; Meltzer, PC; Palmer, EP | 1 |
| Donnemiller, E; Granata, R; Poewe, W; Riccabona, G; Wenning, GK | 1 |
| Carpinelli, A; d'Amico, A; Fazio, F; Franceschi, M; Lucignani, G; Messa, C; Moresco, RM; Paulesu, E; Rizzo, G; Volonté, MA; Zito, F | 1 |
| Baldwin, RM; Charney, DS; Innis, RB; Marek, K; Seibyl, JP; Sheff, K; van Dyck, CH; Zoghbi, S | 1 |
| Innis, RB; Rajeevan, N; Ramsby, SQ; Seibyl, J; Zoghbi, SS; Zubal, IG | 1 |
| Brashear, A; Farlow, MR; Hutchins, GD; Mulholland, GK; Siemers, ER; Zheng, QH | 1 |
| Angelberger, P; Asenbaum, S; Bencsits, G; Brücke, T; Pirker, W; Pruckmayer, M | 1 |
| Bergman, J; Eronen, E; Haaparanta, M; Oikonen, V; Rinne, JO; Ruottinen, H; Solin, O; Sonninen, P | 1 |
| Ballinger, JR; Erami, SS; Ichise, M; Kim, YJ; Lang, AE; Tanaka, F; Vines, D | 1 |
| Dannals, RF; Frost, JJ; Ilgin, N; Ravert, HT; Reich, SG; Zubieta, J | 1 |
| Choe, YS; Kim, JH; Kim, SE; Lee, WY | 1 |
| Futatsubashi, M; Iyo, M; Okada, H; Ouchi, Y; Sakamoto, M; Sekine, Y; Yoshikawa, E | 1 |
| Castronuovo, J; Feigin, A; Innis, RB; Marek, KL; Seibyl, JP; Sheff, K; Zoghbi, S | 1 |
| Brownell, AL; Isacson, O; Jenkins, BG | 1 |
| Ballinger, JR; Ichise, M; Ivo, BD; Vines, DC | 1 |
| Bower, JH; Kuntz, KM; Maraganore, DM; McDonnell, SK; O'Connor, MK; Rocca, WA; Schaid, DJ | 1 |
| Futatsubashi, M; Kanno, T; Nobezawa, S; Okada, H; Ouchi, Y; Sakamoto, M; Torizuka, T; Yoshikawa, E | 1 |
| Ahlskog, JE; Burnett, OL; Maraganore, DM; Matsumoto, JY; O'Connor, MK; Stark, KF; Turk, MF; Uitti, RJ | 1 |
| Berciano, J; Figols, J; González, AM; Pascual, J; Pazos, A | 1 |
| Morris, PG | 1 |
| Fujita, M; Innis, RB; Kugaya, A | 1 |
| Fujiyama, J; Hamano, T; Hirayama, M; Kuriyama, M; Mutoh, T; Tsuchida, T; Yonekura, Y | 1 |
| Barthel, H; Müller, U; Reuter, M; von Cramon, DY; Wächter, T | 1 |
| Bergman, J; Haaparanta, M; Kaasinen, V; Nurmi, E; Rinne, JO; Ruottinen, HM; Solin, O | 1 |
| Harrori, T; Ito, H; Shinotoh, H; Uchida, Y | 1 |
| Ekberg, S; Fall, PA; Granérus, AK; Granérus, G | 1 |
| Ladurner, G; Mair, A; Staffen, W; Trinka, E; Unterrainer, J | 1 |
| Bergman, J; Eskola, O; Hinkka, SM; Nurmi, E; Rinne, JO; Solin, O; Sonninen, P | 1 |
| Asenbaum, S; Bencsits, G; Brücke, T; Deecke, L; Gerschlager, W; Pirker, W; Prayer, D | 1 |
| Futatsubashi, M; Kanno, T; Nobezawa, S; Okada, H; Ouchi, Y; Tanaka, K; Torizuka, T; Yoshikawa, E | 1 |
| Bergman, J; Eskola, O; Nurmi, E; Rinne, OJ; Ruottinen, HM; Solin, O | 1 |
| Guttman, M; Houle, S; Hussey, D; Kish, S; Stewart, D; Wilson, A | 1 |
| Hattori, T; Sakakibara, R; Shinotoh, H; Uchiyama, T; Yamanishi, T; Yoshiyama, M | 1 |
| Kauppinen, T; Kilpeläinen, H; Kuikka, JT; Yang, J | 1 |
| Berke, JD; Hyman, SE; Krause, M; Lavoie, B; Sgambato, V; Vincent, M; Zhu, PP | 1 |
| Early, M; Eberly, S; Fussell, B; Innis, R; Marek, K; Oakes, D; Seibyl, J; van Dyck, C | 1 |
| Innis, RB; Jennings, D; Marek, KL; Seibyl, JP; Varrone, A | 1 |
| Bergmans, P; Booij, J; Stoof, JC; van Emmerik, RE; van Royen, EA; Vellinga, A; Wagenaar, RC; Winogrodzka, A; Wolters, EC | 1 |
| Boja, JW; Carroll, FI; Cline, EJ; Dannals, R; Kuhar, MJ; Lewin, AH; Philip, A; Scheffel, U; Wong, D | 1 |
| Kaufman, MJ; Madras, BK | 1 |
| Langer, SZ; Pimoule, C; Reynolds, GP; Schoemaker, H | 1 |
| Arbilla, S; Javoy-Agid, F; Langer, SZ; Pimoule, C; Scatton, B; Schoemaker, H | 1 |
| Gershon, S; Wallach, MB | 1 |
| Gaasterland, D; Van Woert, MH; Weintraub, MI | 1 |
| Gaasterland, D; van Woert, M; Weintraub, MI | 1 |
| Carmel, PW | 1 |
| Chang, V; Friedman, JH | 1 |
| Checkoway, H; Franklin, GM; Longstreth, WT; Powers, K; Smith-Weller, T; Swanson, PD | 1 |
| Argolo, N; Melo, A; Nóbrega, AC; Sampaio, M | 1 |
| Klingelhöfer, L; Proft, F; Reichmann, H; Riederer, P; Schleiffer, C; Schneider, C; Schwanebeck, U; Storch, A; Wolz, M | 1 |
21 review(s) available for cocaine and Parkinson Disease
| Article | Year |
|---|---|
Butyrylcholinesterase: A Multifaceted Pharmacological Target and Tool.
Topics: Acetylcholine; Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Brain; Butyrylcholinesterase; Cocaine; Cocaine-Related Disorders; Ghrelin; Humans; Molecular Targeted Therapy; Neurotransmitter Agents; Obesity; Parkinson Disease; Recombinant Proteins; Substrate Specificity; Synaptic Transmission | 2020 |
Moonlighting proteins and protein-protein interactions as neurotherapeutic targets in the G protein-coupled receptor field.
Topics: Animals; Antidepressive Agents; Antiparkinson Agents; Antipsychotic Agents; Cocaine; Cocaine-Related Disorders; Depression; Drug Discovery; Humans; Molecular Targeted Therapy; Parkinson Disease; Protein Interaction Mapping; Receptors, G-Protein-Coupled; Schizophrenia | 2014 |
Dopamine transporter SPECT: how to remove subjectivity?
Topics: Cocaine; Dopamine Plasma Membrane Transport Proteins; Humans; Image Interpretation, Computer-Assisted; Multiple System Atrophy; Parkinson Disease; Radiopharmaceuticals; Tomography, Emission-Computed, Single-Photon | 2009 |
Neuroinflammation in the living brain of Parkinson's disease.
Topics: Aged; Brain; Cocaine; Cytokines; Dopamine Plasma Membrane Transport Proteins; Encephalitis; Humans; Isoquinolines; Microglia; Middle Aged; Parkinson Disease; Positron-Emission Tomography; Protein Binding; Radiopharmaceuticals; Tomography, Emission-Computed, Single-Photon | 2009 |
Insights into pathophysiology of punding reveal possible treatment strategies.
Topics: Amphetamine; Behavior, Addictive; Clinical Protocols; Cocaine; Corpus Striatum; Dopamine Agonists; Humans; Models, Biological; Nucleus Accumbens; Parkinson Disease; Psychiatric Status Rating Scales; Severity of Illness Index; Stereotyped Behavior; Stereotypic Movement Disorder | 2010 |
Single-photon emission tomography and dopamine transporter imaging in Parkinson's disease.
Topics: Animals; Brain; Cocaine; Disease Progression; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Humans; Ligands; Longitudinal Studies; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Parkinson Disease; Tomography, Emission-Computed, Single-Photon | 2003 |
Altropane (Boston Life Science).
Topics: Animals; Attention Deficit Disorder with Hyperactivity; Clinical Trials as Topic; Cocaine; Humans; Parkinson Disease; Radiopharmaceuticals; Technology, Pharmaceutical; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 2002 |
Imaging studies in movement disorders.
Topics: Brain; Cocaine; Dihydroxyphenylalanine; Dopamine; Humans; Movement Disorders; Parkinson Disease; Predictive Value of Tests; Radiopharmaceuticals; Severity of Illness Index; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 2003 |
Iometopane: (123)I beta-CIT, dopascan injection, GPI 200, RTI 55.
Topics: Clinical Trials, Phase II as Topic; Cocaine; Dopamine Plasma Membrane Transport Proteins; Humans; Injections, Intravenous; Iodine Radioisotopes; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Paralysis; Parkinson Disease; Radionuclide Imaging; Radiopharmaceuticals | 2003 |
Assessment of neuroimaging techniques as biomarkers of the progression of Parkinson's disease.
Topics: Animals; Basal Ganglia; Biomarkers; Cocaine; Diagnostic Imaging; Dihydroxyphenylalanine; Disease Progression; Dopamine Plasma Membrane Transport Proteins; Humans; Levodopa; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neuropeptides; Parkinson Disease; Radiopharmaceuticals; Technology Assessment, Biomedical; Tetrabenazine; Tomography, Emission-Computed, Single-Photon; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins | 2003 |
Role of dopamine transporter imaging in routine clinical practice.
Topics: Alzheimer Disease; Brain; Cocaine; Dopamine Plasma Membrane Transport Proteins; Essential Tremor; Humans; Iodine Radioisotopes; Lewy Body Disease; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Organotechnetium Compounds; Parkinson Disease; Practice Patterns, Physicians'; Radiopharmaceuticals; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; Tropanes | 2003 |
The role of radiotracer imaging in Parkinson disease.
Topics: Biomarkers; Biotransformation; Blood-Brain Barrier; Carbon Radioisotopes; Clinical Trials as Topic; Cocaine; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Forecasting; Humans; Iodine Radioisotopes; Neurons; Parkinson Disease; Positron-Emission Tomography; Prognosis; Radiopharmaceuticals; Receptors, Dopamine; Substantia Nigra; Tetrabenazine; Tomography, Emission-Computed, Single-Photon | 2005 |
[Advantages and limitations in the assessment of neuroprotective treatment of Parkinson's disease by functional imaging].
Topics: Antiparkinson Agents; Cocaine; Dihydroxyphenylalanine; Fluorine Radioisotopes; Humans; Parkinson Disease; Radiopharmaceuticals; Tomography, Emission-Computed, Single-Photon | 2005 |
How useful is (123I) beta-CIT SPECT in the diagnosis of Parkinson's disease?
Topics: Brain; Cocaine; Essential Tremor; Humans; Iodine Radioisotopes; Parkinson Disease; Radiopharmaceuticals; Sensitivity and Specificity; Tomography, Emission-Computed, Single-Photon | 2006 |
Single-photon emission tomography imaging of dopamine terminal innervation: a potential clinical tool in Parkinson's disease.
Topics: Carrier Proteins; Cocaine; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Fluorine Radioisotopes; Humans; Iodine Radioisotopes; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Endings; Nerve Tissue Proteins; Parkinson Disease; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 1994 |
IBZM- and CIT-SPECT of the dopaminergic system in parkinsonism.
Topics: Benzamides; Brain; Cocaine; Diagnosis, Differential; Dopamine; Dopamine Antagonists; Humans; Iodine Radioisotopes; Parkinson Disease; Parkinson Disease, Secondary; Pyrrolidines; Receptors, Dopamine D2; Risk Factors; Tomography, Emission-Computed, Single-Photon | 1997 |
The dopamine transporter: a crucial component regulating dopamine transmission.
Topics: Amphetamines; Animals; Brain; Carrier Proteins; Central Nervous System Stimulants; Cocaine; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Gene Dosage; Genotype; Homeostasis; Humans; Hyperkinesis; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Knockout; Mice, Transgenic; Nerve Tissue Proteins; Parkinson Disease; Phenotype; Rats; Schizophrenia; Substance-Related Disorders | 1997 |
Magnetic resonance imaging and magnetic resonance spectroscopy assessment of brain function in experimental animals and man.
Topics: Animals; Brain; Cocaine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Parkinson Disease; Substance-Related Disorders | 1999 |
Applications of SPECT imaging of dopaminergic neurotransmission in neuropsychiatric disorders.
Topics: Animals; Benzamides; Brain; Carrier Proteins; Cocaine; Disease Progression; Dopamine Plasma Membrane Transport Proteins; Humans; Iodine Radioisotopes; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Parkinson Disease; Pyrrolidines; Receptors, Dopamine D2; Schizophrenia; Synaptic Transmission; Tomography, Emission-Computed, Single-Photon | 2000 |
Altropane. O 587.
Topics: Clinical Trials as Topic; Cocaine; Drug Industry; Humans; Parkinson Disease; Tomography, Emission-Computed, Single-Photon | 2002 |
High potency cocaine analogs: neurochemical, imaging, and behavioral studies.
Topics: Animals; Brain; Carrier Proteins; Cocaine; Dopamine; Humans; Motor Activity; Parkinson Disease; Structure-Activity Relationship; Tomography, Emission-Computed; Tritium | 1992 |
22 trial(s) available for cocaine and Parkinson Disease
| Article | Year |
|---|---|
Impact of disclosure of individual imaging results in a multi-center Parkinson clinical trial.
Topics: Antipsychotic Agents; Carbazoles; Cocaine; Dopamine Plasma Membrane Transport Proteins; Female; Health Surveys; Humans; Longitudinal Studies; Male; Parkinson Disease; Radiopharmaceuticals; Retrospective Studies; Tomography, Emission-Computed, Single-Photon; Treatment Outcome | 2014 |
A novel computer-assisted image analysis of [123I]β-CIT SPECT images improves the diagnostic accuracy of parkinsonian disorders.
Topics: Aged; Algorithms; Analysis of Variance; Brain; Case-Control Studies; Cocaine; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Multiple System Atrophy; Parkinson Disease; Parkinsonian Disorders; Regression Analysis; Reproducibility of Results; Sensitivity and Specificity; Supranuclear Palsy, Progressive; Tomography, Emission-Computed, Single-Photon | 2011 |
The influence of residual nor-β-CFT in 11C CFT injection on the Parkinson disease diagnosis: a 11C CFT PET study.
Topics: Carbon Radioisotopes; Cocaine; Drug Residues; Female; Fluorodeoxyglucose F18; Humans; Injections, Intravenous; Male; Middle Aged; Parkinson Disease; Positron-Emission Tomography | 2012 |
Transplantation of human retinal pigment epithelium cells in the treatment for Parkinson disease.
Topics: Aged; Aged, 80 and over; Antigens, CD; Bucladesine; Carbon Isotopes; Cell Differentiation; Cells, Cultured; Cocaine; Dopamine Uptake Inhibitors; Female; Fetus; Flow Cytometry; Growth Substances; Humans; Longitudinal Studies; Magnetic Resonance Imaging; Male; Middle Aged; Neural Stem Cells; Neurons; Parkinson Disease; Pituitary Adenylate Cyclase-Activating Polypeptide; Positron-Emission Tomography; Retinal Pigment Epithelium; Severity of Illness Index; Time Factors; Treatment Outcome; Tretinoin | 2012 |
Serotonin transporters in the midbrain of Parkinson's disease patients: a study with 123I-beta-CIT SPECT.
Topics: Adult; Aged; Aged, 80 and over; Carrier Proteins; Cocaine; Dopamine; Female; Humans; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mesencephalon; Metabolic Clearance Rate; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Radiopharmaceuticals; Serotonin; Serotonin Plasma Membrane Transport Proteins; Tomography, Emission-Computed, Single-Photon | 2003 |
The application of statistical parametric mapping to 123I-FP-CIT SPECT in dementia with Lewy bodies, Alzheimer's disease and Parkinson's disease.
Topics: Aged; Aging; Alzheimer Disease; Brain; Brain Mapping; Cocaine; Diagnosis, Differential; Dopamine; Female; Humans; Image Processing, Computer-Assisted; Lewy Body Disease; Male; Neuropsychological Tests; Parkinson Disease; Radiopharmaceuticals; ROC Curve; Tomography, Emission-Computed, Single-Photon | 2004 |
Imaging of dopamine transporters and D2 receptors in patients with Parkinson's disease and multiple system atrophy.
Topics: Adult; Aged; Benzamides; Brain; Cocaine; Diagnosis, Differential; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Multiple System Atrophy; Nerve Tissue Proteins; Parkinson Disease; Pyrrolidines; Radiopharmaceuticals; Receptors, Dopamine D2; Reproducibility of Results; Sensitivity and Specificity; Tomography, Emission-Computed, Single-Photon | 2004 |
Levodopa and the progression of Parkinson's disease.
Topics: Aged; Cocaine; Corpus Striatum; Disease Progression; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Degeneration; Nerve Tissue Proteins; Oxidative Stress; Parkinson Disease; Presynaptic Terminals; Substantia Nigra; Tomography, Emission-Computed, Single-Photon; Treatment Outcome | 2005 |
How useful is [123I]beta-CIT SPECT in clinical practice?
Topics: Age Factors; Aged; Cocaine; Diagnosis, Differential; Essential Tremor; Female; Humans; Male; Middle Aged; Parkinson Disease; Radiopharmaceuticals; Sensitivity and Specificity; Tomography, Emission-Computed, Single-Photon | 2005 |
N.c.a. radiosynthesis of [123,124I]beta-CIT, plasma analysis and pharmacokinetic studies with SPECT and PET.
Topics: Brain; Cerebral Cortex; Cocaine; Humans; Iodine Radioisotopes; Isotope Labeling; Neostriatum; Parkinson Disease; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 1995 |
Evaluation of [123I] beta-CIT binding with SPECT in controls, early and late Parkinson's disease.
Topics: Adult; Brain; Caudate Nucleus; Cocaine; Disease Progression; Dopamine Agents; Female; Humans; Injections, Intravenous; Male; Middle Aged; Parkinson Disease; Putamen; Tomography, Emission-Computed, Single-Photon | 1995 |
Rapid detection of Parkinson's disease by SPECT with altropane: a selective ligand for dopamine transporters.
Topics: Adolescent; Adult; Aged; Brain; Brain Chemistry; Carrier Proteins; Child; Cocaine; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Iodine Radioisotopes; Ligands; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Receptors, Dopamine D1; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 1998 |
Effect of treatment with L-dopa/carbidopa or L-selegiline on striatal dopamine transporter SPECT imaging with [123I]beta-CIT.
Topics: Aged; Antiparkinson Agents; Biological Transport; Carbidopa; Cocaine; Corpus Striatum; Dopamine; Drug Therapy, Combination; Female; Humans; Iodine Radioisotopes; Levodopa; Male; Monoamine Oxidase; Occipital Lobe; Parkinson Disease; Selegiline; Tomography, Emission-Computed, Single-Photon; Treatment Outcome | 1999 |
The effect of dopamine agonist therapy on dopamine transporter imaging in Parkinson's disease.
Topics: Aged; Brain; Brain Mapping; Carbidopa; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine Agonists; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Female; Humans; Iodine Radioisotopes; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Motor Skills; Nerve Tissue Proteins; Parkinson Disease; Pergolide; Putamen; Tomography, Emission-Computed, Single-Photon | 1999 |
[Dopamine transporter SPECT in patients with Parkinson's disease].
Topics: Adult; Aged; Brain; Carrier Proteins; Cocaine; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Radiopharmaceuticals; Tomography, Emission-Computed, Single-Photon | 2000 |
Pramipexole vs levodopa as initial treatment for Parkinson disease: A randomized controlled trial. Parkinson Study Group.
Topics: Antiparkinson Agents; Benzothiazoles; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine; Dopamine Agents; Dopamine Agonists; Dopamine Plasma Membrane Transport Proteins; Double-Blind Method; Dyskinesias; Female; Humans; Iodine Radioisotopes; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Pramipexole; Proportional Hazards Models; Quality of Life; Radiopharmaceuticals; Thiazoles; Tomography, Emission-Computed, Single-Photon | 2000 |
ECT in Parkinson's disease-dopamine transporter visualised by [123I]-beta-CIT SPECT.
Topics: Aged; Aged, 80 and over; Brain Chemistry; Carrier Proteins; Cocaine; Dopamine Plasma Membrane Transport Proteins; Electroconvulsive Therapy; Female; Humans; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Parkinson Disease; Predictive Value of Tests; Tomography, Emission-Computed, Single-Photon; Treatment Outcome | 2000 |
Reproducibility and effect of levodopa on dopamine transporter function measurements: a [18F]CFT PET study.
Topics: Adult; Aged; Antiparkinson Agents; Biological Transport; Carrier Proteins; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Fluorine Radioisotopes; Humans; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Reproducibility of Results; Tomography, Emission-Computed | 2000 |
Changes in dopamine availability in the nigrostriatal and mesocortical dopaminergic systems by gait in Parkinson's disease.
Topics: Aged; Arteries; Blood Pressure; Carbon Radioisotopes; Carrier Proteins; Caudate Nucleus; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Frontal Lobe; Gait; Gyrus Cinguli; Heart Rate; Humans; Magnetic Resonance Imaging; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Putamen; Substantia Nigra; Tomography, Emission-Computed; Walking | 2001 |
Influence of L-dopa and pramipexole on striatal dopamine transporter in early PD.
Topics: Aged; Antiparkinson Agents; Benzothiazoles; Brain Chemistry; Carbon Radioisotopes; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Drug Therapy, Combination; Female; Humans; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Pramipexole; Receptors, Dopamine; Thiazoles; Tomography, Emission-Computed | 2001 |
Dopamine transporter brain imaging to assess the effects of pramipexole vs levodopa on Parkinson disease progression.
Topics: Aged; Antiparkinson Agents; Benzothiazoles; Brain; Cocaine; Disease Progression; Dopamine; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Iodine Radioisotopes; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Degeneration; Nerve Tissue Proteins; Parkinson Disease; Pramipexole; Radiopharmaceuticals; Randomized Controlled Trials as Topic; Regression Analysis; Thiazoles; Tomography, Emission-Computed, Single-Photon; Treatment Outcome | 2002 |
Comparison of chocolate to cacao-free white chocolate in Parkinson's disease: a single-dose, investigator-blinded, placebo-controlled, crossover trial.
Topics: Adult; Aged; Cacao; Candy; Cross-Over Studies; Female; Humans; Male; Middle Aged; Parkinson Disease; Research Personnel; Single-Blind Method | 2012 |
139 other study(ies) available for cocaine and Parkinson Disease
| Article | Year |
|---|---|
Deep Brain Stimulation Compared With Contingency Management for the Treatment of Cocaine Use Disorders: A Threshold and Cost-Effectiveness Analysis.
Topics: Cocaine; Cost-Benefit Analysis; Deep Brain Stimulation; Humans; Parkinson Disease; Quality of Life; Quality-Adjusted Life Years | 2022 |
2-(Fluoromethoxy)-4'-(
Topics: Animals; Biphenyl Compounds; Cocaine; Dopamine; Dopamine Agents; Dopamine Agonists; Humans; Indazoles; Levodopa; Ligands; Mice; Nitrofurans; Parkinson Disease; Receptors, Dopamine; Receptors, Dopamine D1 | 2022 |
Sleep benefit in patients with Parkinson's disease is associated with the dopamine transporter expression in putamen.
Topics: Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Humans; Levodopa; Parkinson Disease; Putamen; Sleep; Tremor | 2023 |
Alpha-synuclein/synapsin III pathological interplay boosts the motor response to methylphenidate.
Topics: alpha-Synuclein; Animals; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Gait Disorders, Neurologic; Lewy Bodies; Methylphenidate; Mice; Mice, Inbred C57BL; Parkinson Disease; Substantia Nigra; Synapsins; Synucleinopathies | 2020 |
Positron emission tomography/computed tomography dual imaging using 18-fluorine flurodeoxyglucose and 11C-labeled 2-β-carbomethoxy-3-β-(4-fluorophenyl) tropane for the severity assessment of Parkinson disease.
Topics: Aged; Basal Ganglia; Brain; Carbon Radioisotopes; Cocaine; Female; Fluorine Radioisotopes; Glucose; Humans; Male; Middle Aged; Parkinson Disease; Positron Emission Tomography Computed Tomography; Prospective Studies; Severity of Illness Index | 2020 |
Parkinson's disease after psychosurgery for the treatment of cocaine addiction.
Topics: Cocaine; Cocaine-Related Disorders; Humans; Parkinson Disease; Psychosurgery | 2021 |
Evaluation of RNA Blood Biomarkers in Individuals at Risk of Parkinson's Disease.
Topics: Aged; Aged, 80 and over; Biomarkers; Carrier Proteins; Cocaine; Female; Humans; Male; Membrane Proteins; Middle Aged; Parkinson Disease; Repressor Proteins; RNA; Severity of Illness Index; Statistics as Topic; Superoxide Dismutase; Thyroid Hormone-Binding Proteins; Thyroid Hormones; Tomography, Emission-Computed, Single-Photon | 2017 |
[Questionnaire survey of Scans Without Evidence of Dopaminergic Deficit (SWEDD) in Japan].
Topics: Adult; Aged; Aged, 80 and over; Cocaine; Corpus Striatum; Diagnosis, Differential; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Female; Humans; Japan; Male; Middle Aged; Parkinson Disease; Surveys and Questionnaires; Tomography, Emission-Computed, Single-Photon | 2018 |
Neuropathologic correlates of amyloid and dopamine transporter imaging in Lewy body disease.
Topics: Aged; Aged, 80 and over; Amyloid beta-Peptides; Aniline Compounds; Autopsy; Brain; Cocaine; Contrast Media; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Lewy Body Disease; Male; Middle Aged; Parkinson Disease; Positron-Emission Tomography; Thiazoles | 2019 |
Do non-motor symptoms in Parkinson's disease differ from essential tremor before initial diagnosis? A clinical and scintigraphic study.
Topics: Aged; Cocaine; Essential Tremor; Female; Humans; Male; Middle Aged; Parkinson Disease; Radiopharmaceuticals; Tomography, Emission-Computed, Single-Photon | 2014 |
Relation between microPET imaging and rotational behavior in a parkinsonian rat model induced by medial forebrain bundle axotomy.
Topics: Animals; Apomorphine; Axotomy; Cocaine; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Dopamine Uptake Inhibitors; Functional Laterality; Male; Medial Forebrain Bundle; Parkinson Disease; Raclopride; Radionuclide Imaging; Rats; Rats, Wistar; Stereotyped Behavior; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase | 2014 |
Imaging prodromal Parkinson disease: the Parkinson Associated Risk Syndrome Study.
Topics: Aged; Cocaine; Cohort Studies; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Male; Middle Aged; Neurologic Examination; Olfaction Disorders; Parkinson Disease; Prodromal Symptoms; Radiopharmaceuticals; Risk Factors; Self Report; Surveys and Questionnaires; Tomography, Emission-Computed, Single-Photon | 2014 |
Comparison of sleep and other non-motor symptoms between SWEDDs patients and de novo Parkinson's disease patients.
Topics: Aged; Aged, 80 and over; Cocaine; Female; Gastrointestinal Diseases; Humans; Male; Middle Aged; Parkinson Disease; Positron-Emission Tomography; Quality of Life; Radiopharmaceuticals; Sleep Wake Disorders; Tropanes | 2014 |
α-synuclein and synapsin III cooperatively regulate synaptic function in dopamine neurons.
Topics: alpha-Synuclein; Animals; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Gene Silencing; Humans; Mice, Inbred C57BL; Mice, Transgenic; Models, Biological; Motor Activity; Mutant Proteins; Parkinson Disease; Presynaptic Terminals; Protein Aggregates; Protein Binding; Putamen; Subcellular Fractions; Synapses; Synapsins; Synaptic Vesicles | 2015 |
Cognition in individuals at risk for Parkinson's: Parkinson associated risk syndrome (PARS) study findings.
Topics: Aged; Aged, 80 and over; Anxiety; Attention; Cocaine; Cognition Disorders; Cohort Studies; Executive Function; Female; Humans; Language; Male; Memory; Middle Aged; Neurogenic Bowel; Neuropsychological Tests; Olfaction Disorders; Parkinson Disease; Protein Binding; Radiopharmaceuticals; Self Report; Severity of Illness Index; Statistics, Nonparametric; Surveys and Questionnaires; Tomography, Emission-Computed, Single-Photon; Visual Perception | 2016 |
Onset-related subtypes of Parkinson's disease differ in the patterns of striatal dopaminergic dysfunction: A positron emission tomography study.
Topics: Adult; Age of Onset; Aged; Carbon Radioisotopes; Caudate Nucleus; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Female; Humans; Male; Middle Aged; Neuroimaging; Organ Specificity; Parkinson Disease; Positron-Emission Tomography; Putamen; Radiopharmaceuticals; Tissue Distribution | 2015 |
PET Radioligands Reveal the Basis of Dementia in Parkinson's Disease and Dementia with Lewy Bodies.
Topics: Alzheimer Disease; Aniline Compounds; Brain; Carbolines; Cocaine; Cognitive Dysfunction; Cross-Sectional Studies; Diagnosis, Differential; Lewy Body Disease; Magnetic Resonance Imaging; Neuropsychological Tests; Parkinson Disease; Prospective Studies; Radionuclide Imaging; Radiopharmaceuticals; Survival Analysis; Thiazoles | 2016 |
Suite PET/CT neuroimaging for the diagnosis of Parkinson's disease: statistical parametric mapping analysis.
Topics: Adult; Aged; Aged, 80 and over; Brain; Brain Mapping; Case-Control Studies; Cocaine; Dopamine Plasma Membrane Transport Proteins; Female; Fluorodeoxyglucose F18; Functional Neuroimaging; Glucose; Humans; Male; Middle Aged; Molecular Imaging; Parkinson Disease; Positron Emission Tomography Computed Tomography; Raclopride; Radiopharmaceuticals; Receptors, Dopamine D2; Young Adult | 2017 |
Selective hyposmia in Parkinson disease: association with hippocampal dopamine activity.
Topics: Aged; Carbon Isotopes; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Female; Hippocampus; Humans; Male; Mental Status Schedule; Middle Aged; Models, Biological; Neural Pathways; Olfaction Disorders; Parkinson Disease; Radionuclide Imaging | 2008 |
Multitracer assessment of dopamine function after transplantation of embryonic stem cell-derived neural stem cells in a primate model of Parkinson's disease.
Topics: Animals; Carbon Radioisotopes; Cells, Cultured; Cocaine; Disease Models, Animal; Dopamine; Dopamine Agents; Embryonic Stem Cells; Levodopa; Macaca fascicularis; Methamphetamine; Movement Disorders; Neurons; Parkinson Disease; Positron-Emission Tomography; Putamen; Raclopride; Tyrosine 3-Monooxygenase | 2009 |
In vitro dopaminergic neuroprotective and in vivo antiparkinsonian-like effects of Delta 3,2-hydroxybakuchiol isolated from Psoralea corylifolia (L.).
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Antiparkinson Agents; Cell Line; CHO Cells; Cocaine; Cricetinae; Cricetulus; Dopamine; Dopamine Agents; Humans; Male; Mice; Mice, Inbred C57BL; Neurons; Neuroprotective Agents; Norepinephrine; Parkinson Disease; Phenols; Psoralea; Rats; Rats, Sprague-Dawley; Synaptosomes; Tyrosine 3-Monooxygenase | 2009 |
Substantia nigra echogenicity: A structural correlate of functional impairment of the dopaminergic striatal projection in Parkinson's disease.
Topics: Aged; Antiparkinson Agents; Cocaine; Corpus Striatum; Dopamine; Dopamine Agonists; Female; Humans; Iodine Radioisotopes; Male; Middle Aged; Neural Pathways; Neurons; Parkinson Disease; Radiopharmaceuticals; Substantia Nigra; Tomography, Emission-Computed, Single-Photon; Ultrasonography, Doppler, Transcranial | 2009 |
Expanding the clinical phenotype of SNCA duplication carriers.
Topics: Adult; Aged; alpha-Synuclein; Brain; Carbon Isotopes; Chromosome Mapping; Cocaine; Family Health; Female; Fluorodeoxyglucose F18; Gene Dosage; Gene Duplication; Genetic Predisposition to Disease; Humans; Male; Middle Aged; Parkinson Disease; Phenotype; Positron-Emission Tomography; Raclopride; REM Sleep Behavior Disorder; Sensory Thresholds; Smell; Young Adult | 2009 |
Analysis of SCA2 and SCA3/MJD repeats in Parkinson's disease in mainland China: genetic, clinical, and positron emission tomography findings.
Topics: Adult; Aged; Ataxin-3; Ataxins; Carbon Isotopes; China; Cocaine; DNA Mutational Analysis; Family Health; Female; Humans; Male; Middle Aged; Nerve Tissue Proteins; Nuclear Proteins; Parkinson Disease; Positron-Emission Tomography; Repressor Proteins; Trinucleotide Repeat Expansion | 2009 |
Drug-induced compulsive behaviors: exceptions to the rule.
Topics: Antiparkinson Agents; Carbidopa; Cocaine; Cocaine-Related Disorders; Compulsive Behavior; Disruptive, Impulse Control, and Conduct Disorders; Dopamine Agonists; Humans; Parkinson Disease | 2009 |
Diagnosing premotor Parkinson's disease using a two-step approach combining olfactory testing and DAT SPECT imaging.
Topics: Cocaine; Dopamine Plasma Membrane Transport Proteins; Humans; Olfaction Disorders; Olfactory Pathways; Parkinson Disease; Radiopharmaceuticals; Risk Factors; Substantia Nigra; Tomography, Emission-Computed, Single-Photon | 2009 |
Progression from unilateral to bilateral parkinsonism in early Parkinson disease: implication of mesocortical dopamine dysfunction by PET.
Topics: Adult; Aged; Cerebral Cortex; Cocaine; Disease Progression; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Functional Laterality; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Middle Aged; Parkinson Disease; Positron-Emission Tomography; Prognosis; Radiopharmaceuticals; Regression Analysis | 2010 |
Estimation of further disease progression of Parkinson's disease by dopamin transporter scan vs clinical rating.
Topics: Aged; Aged, 80 and over; Cocaine; Disease Progression; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Male; Middle Aged; Parkinson Disease; Predictive Value of Tests; Radiopharmaceuticals; Retrospective Studies; Tomography, Emission-Computed, Single-Photon | 2011 |
Correlative single photon emission computed tomography imaging of [123I]altropane binding in the rat model of Parkinson's.
Topics: Animals; Behavior, Animal; Biomarkers; Cocaine; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Iodine Radioisotopes; Neostriatum; Neural Stem Cells; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Stem Cell Transplantation; Tomography, Emission-Computed, Single-Photon | 2011 |
Serotonergic modulation of receptor occupancy in rats treated with L-DOPA after unilateral 6-OHDA lesioning.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Antiparkinson Agents; Autoradiography; Carbon Isotopes; Cocaine; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Dyskinesia, Drug-Induced; Female; Functional Laterality; Levodopa; Microdialysis; Motor Activity; Oxidopamine; Parkinson Disease; Positron-Emission Tomography; Protein Binding; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Serotonin; Serotonergic Neurons; Serotonin Receptor Agonists | 2012 |
Progression of dopamine transporter decline in patients with the Parkinson variant of multiple system atrophy: a voxel-based analysis of [123I]β-CIT SPECT.
Topics: Brain; Cocaine; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Image Interpretation, Computer-Assisted; Male; Middle Aged; Motor Activity; Multiple System Atrophy; Parkinson Disease; Time Factors; Tomography, Emission-Computed, Single-Photon | 2012 |
Dopamine transporter imaging is associated with long-term outcomes in Parkinson's disease.
Topics: Aged; Cocaine; Cohort Studies; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Female; Functional Laterality; Humans; Linear Models; Male; Mental Status Schedule; Middle Aged; Parkinson Disease; Radiopharmaceuticals; Tomography, Emission-Computed, Single-Photon | 2012 |
Left hemispheric predominance of nigrostriatal dysfunction in Parkinson's disease.
Topics: Aged; Cocaine; Dopamine Plasma Membrane Transport Proteins; Female; Functional Laterality; Humans; Male; Middle Aged; Parkinson Disease; Putamen; Radiopharmaceuticals; Severity of Illness Index; Tomography, Emission-Computed, Single-Photon | 2012 |
Alternative splicing of AMPA receptor subunits in the 6-OHDA-lesioned rat model of Parkinson's disease and L-DOPA-induced dyskinesia.
Topics: Adamantane; Alternative Splicing; Animals; Antiparkinson Agents; Cocaine; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Iodine Isotopes; Levodopa; Male; Motor Activity; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Receptors, AMPA; RNA, Messenger; Sympatholytics | 2013 |
[123I]beta-CIT SPECT distinguishes vascular parkinsonism from Parkinson's disease.
Topics: Aged; Aged, 80 and over; Cocaine; Corpus Striatum; Diagnosis, Differential; Dopamine; Female; Humans; Male; Middle Aged; Nerve Degeneration; Parkinson Disease; Parkinson Disease, Secondary; Radiopharmaceuticals; Tomography, Emission-Computed, Single-Photon | 2002 |
Dopamine transporter density is decreased in parkinsonian patients with a history of manganese exposure: what does it mean?
Topics: Causality; Cocaine; Corpus Striatum; Diagnosis, Differential; Dopamine; Dopamine Plasma Membrane Transport Proteins; Humans; Iodine Radioisotopes; Male; Manganese; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Occupational Exposure; Parkinson Disease; Parkinson Disease, Secondary; Tomography, Emission-Computed, Single-Photon | 2002 |
Brain imaging to assess the effects of dopamine agonists on progression of Parkinson disease.
Topics: Antiparkinson Agents; Benzothiazoles; Brain; Cocaine; Dopamine Agonists; Dopamine Plasma Membrane Transport Proteins; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Parkinson Disease; Pramipexole; Radiopharmaceuticals; Thiazoles; Tomography, Emission-Computed, Single-Photon | 2002 |
Biodistribution study of [99mTc] TRODAT-1 alone or combined with other dopaminergic drugs in mice with macroautoradiography.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Autoradiography; Brain; Cocaine; Dopamine Agents; Humans; Levodopa; Male; Methylphenidate; Mice; Mice, Inbred ICR; Organotechnetium Compounds; Parkinson Disease; Radionuclide Imaging; Radiopharmaceuticals; Tissue Distribution; Tropanes | 2002 |
Clinical impact of diagnostic SPET investigations with a dopamine re-uptake ligand.
Topics: Adult; Aged; Aged, 80 and over; Antiparkinson Agents; Basal Ganglia Diseases; Cocaine; Corpus Striatum; Diagnosis, Differential; Dopamine Plasma Membrane Transport Proteins; Dystonia; Essential Tremor; Female; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Parkinsonian Disorders; Patient Care Management; Reproducibility of Results; Retrospective Studies; Sensitivity and Specificity; Tomography, Emission-Computed, Single-Photon | 2002 |
Periodic leg movements in patients with Parkinson's disease are associated with reduced striatal dopamine transporter binding.
Topics: Aged; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Nocturnal Myoclonus Syndrome; Parkinson Disease; Polysomnography; Radiopharmaceuticals; Tomography, Emission-Computed, Single-Photon | 2003 |
Objective measures for the progression of Parkinson's disease.
Topics: Binding Sites; Cocaine; Corpus Striatum; Disease Progression; Dopamine; Dopamine Plasma Membrane Transport Proteins; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Degeneration; Nerve Tissue Proteins; Parkinson Disease; Radiopharmaceuticals; Substantia Nigra; Tomography, Emission-Computed, Single-Photon | 2003 |
[(123)I]beta-CIT SPECT is a useful method for monitoring dopaminergic degeneration in early stage Parkinson's disease.
Topics: Antiparkinson Agents; Benzothiazoles; Caudate Nucleus; Cocaine; Corpus Striatum; Disease Progression; Female; Humans; Male; Nerve Degeneration; Parkinson Disease; Pergolide; Pramipexole; Putamen; Radiopharmaceuticals; Receptors, Dopamine D2; Reproducibility of Results; Thiazoles; Tomography, Emission-Computed, Single-Photon; Treatment Outcome | 2003 |
[[123I]beta-CIT SPECT imaging of dopamine and serotonin transporters in Parkinson's disease and multiple system atrophy.
Topics: Brain; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Multiple System Atrophy; Nerve Tissue Proteins; Organ Specificity; Parkinson Disease; Radionuclide Imaging; Radiopharmaceuticals; Serotonin Plasma Membrane Transport Proteins | 2003 |
[SPECT imaging using [123I]beta-CIT and [123I]IBF in extrapyramidal diseases].
Topics: Aged; Basal Ganglia Diseases; Benzofurans; Cocaine; Dopamine Plasma Membrane Transport Proteins; Humans; Iodine Radioisotopes; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Pyrrolidines; Radiopharmaceuticals; Tomography, Emission-Computed, Single-Photon | 2003 |
Camptocormia in idiopathic Parkinson's disease: [(123)I]beta-CIT SPECT and clinical characteristics.
Topics: Aged; Cocaine; Dystonia; Humans; Lumbosacral Region; Male; Middle Aged; Parkinson Disease; Posture; Radiopharmaceuticals; Spine; Thoracic Vertebrae; Tomography, Emission-Computed, Single-Photon | 2003 |
Correlation of dopamine transporter imaging with parkinsonian motor handicap: how close is it?
Topics: Activities of Daily Living; Aged; Brain; Cocaine; Corpus Striatum; Diagnosis, Differential; Dihydroxyphenylalanine; Dominance, Cerebral; Dopamine Plasma Membrane Transport Proteins; Female; Fluorine Radioisotopes; Humans; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Neural Pathways; Neurologic Examination; Parkinson Disease; Sensitivity and Specificity; Substantia Nigra; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 2003 |
[123I-Ioflupane brain scintigraphy (DaTScan) to demonstrate loss of nigrostratal dopaminergic neurons: principles and applications].
Topics: Cocaine; Dihydroxyphenylalanine; Dystonia; Humans; Iodine Radioisotopes; Neostriatum; Parkinson Disease; Radionuclide Imaging; Radiopharmaceuticals; Substantia Nigra | 2003 |
Measuring the rate of progression of Parkinson's disease over a 5-year period with beta-CIT SPECT.
Topics: Binding Sites; Cocaine; Cognition Disorders; Corpus Striatum; Disease Progression; Dopamine Plasma Membrane Transport Proteins; Female; Follow-Up Studies; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Neuropsychological Tests; Parkinson Disease; Radiopharmaceuticals; Severity of Illness Index; Time Factors; Tomography, Emission-Computed, Single-Photon | 2003 |
[Basic study of dopamine transporter imaging with 131I-beta-CIT].
Topics: Animals; Brain; Cats; Cocaine; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Female; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred Strains; Nerve Tissue Proteins; Parkinson Disease; Tomography, Emission-Computed, Single-Photon | 2003 |
123I-beta-CIT SPECT for imaging serotonin transporters in Parkinson's disease.
Topics: Brain; Carrier Proteins; Cocaine; Humans; Iodine Radioisotopes; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Parkinson Disease; Radiopharmaceuticals; Serotonin; Serotonin Plasma Membrane Transport Proteins; Tomography, Emission-Computed, Single-Photon | 2004 |
Idiopathic hyposmia as a preclinical sign of Parkinson's disease.
Topics: Aged; Cocaine; Corpus Striatum; Dopamine; Female; Follow-Up Studies; Functional Laterality; Humans; Male; Middle Aged; Neurologic Examination; Neuropsychological Tests; Olfaction Disorders; Parkinson Disease; Prospective Studies; Radiopharmaceuticals; Siblings; Substantia Nigra; Surveys and Questionnaires; Tomography, Emission-Computed, Single-Photon | 2004 |
Abnormalities of dopaminergic neurotransmission in SCA2: a combined 123I-betaCIT and 123I-IBZM SPECT study.
Topics: Adult; Basal Ganglia; Benzamides; Cerebellum; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dystonic Disorders; Female; Humans; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Parkinsonian Disorders; Pyrrolidines; Receptors, Dopamine D2; Reference Values; Spinocerebellar Ataxias; Synaptic Transmission; Tomography, Emission-Computed, Single-Photon | 2004 |
Sleep microstructure and neurodegeneration as measured by [123I]beta-CIT SPECT in treated patients with Parkinson's disease.
Topics: Aged; Case-Control Studies; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Hypothalamus; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Degeneration; Nerve Tissue Proteins; Parkinson Disease; Polysomnography; Radiopharmaceuticals; Serotonin; Sleep; Thalamus; Tomography, Emission-Computed, Single-Photon | 2004 |
Early-stage [123I]beta-CIT SPECT and long-term clinical follow-up in patients with an initial diagnosis of Parkinson's disease.
Topics: Cocaine; Corpus Striatum; Diagnosis, Differential; Dopamine Plasma Membrane Transport Proteins; Female; Follow-Up Studies; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Prognosis; Radiopharmaceuticals; Retrospective Studies; Tissue Distribution; Tomography, Emission-Computed, Single-Photon | 2005 |
Cocaine and phenylephrine eye drop test for Parkinson disease.
Topics: Adrenergic alpha-Agonists; Aged; Cocaine; Dopamine Uptake Inhibitors; Female; Humans; Male; Middle Aged; Mydriasis; Ophthalmic Solutions; Parkinson Disease; Phenylephrine; Pupil; Sympathetic Nervous System | 2005 |
Voxel-wise analysis of [123I]beta-CIT SPECT differentiates the Parkinson variant of multiple system atrophy from idiopathic Parkinson's disease.
Topics: Aged; Case-Control Studies; Caudate Nucleus; Cocaine; Corpus Striatum; Diagnosis, Differential; Discriminant Analysis; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Linear Models; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mesencephalon; Middle Aged; Multiple System Atrophy; Nerve Tissue Proteins; Parkinson Disease; Radiopharmaceuticals; Receptors, Dopamine D2; Tomography, Emission-Computed, Single-Photon | 2005 |
Positron emission tomography changes in PARK1 mutation.
Topics: Adult; alpha-Synuclein; Brain; Carbon Radioisotopes; Chromosome Aberrations; Cocaine; DNA Mutational Analysis; Female; Gene Expression; Genes, Dominant; Genetic Carrier Screening; Humans; Lewy Body Disease; Middle Aged; Neurologic Examination; Parkinson Disease; Phenotype; Positron-Emission Tomography; Raclopride; Receptors, Dopamine; Receptors, Presynaptic | 2006 |
Long-term 24-hour duodenal infusion of levodopa: outcome and dose requirements.
Topics: Animals; Antiparkinson Agents; Cocaine; Dihydroxyphenylalanine; Dopamine Agents; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Duodenum; Humans; Indoles; Infusion Pumps; Levodopa; Parkinson Disease; Positron-Emission Tomography; Radiopharmaceuticals; Treatment Outcome | 2006 |
Repeated l-DOPA treatment increases c-fos and BDNF mRNAs in the subthalamic nucleus in the 6-OHDA rat model of Parkinson's disease.
Topics: Adrenergic Agents; Animals; Antiparkinson Agents; Brain-Derived Neurotrophic Factor; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug Administration Schedule; Gene Expression Regulation; Levodopa; Male; Oxidopamine; Parkinson Disease; Protein Binding; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; RNA, Messenger; Subthalamic Nucleus; Tritium | 2006 |
Inhaled cocaine used to relieve "off" periods in patients with Parkinson disease and unpredictable motor fluctuations: a report of 2 cases.
Topics: Administration, Inhalation; Cocaine; Dopamine Uptake Inhibitors; Drug Administration Schedule; Dyskinesia, Drug-Induced; Female; Humans; Levodopa; Middle Aged; Parkinson Disease; Self Medication | 2006 |
Dopaminergic neuronal dysfunction associated with parkinsonism in both a Gaucher disease patient and a carrier.
Topics: Adult; Carbon Radioisotopes; Cocaine; Dopamine; Dopamine Antagonists; Gaucher Disease; Heterozygote; Humans; Male; Neurons; Parkinson Disease; Positron-Emission Tomography; Raclopride | 2007 |
Optimized, automated striatal uptake analysis applied to SPECT brain scans of Parkinson's disease patients.
Topics: Aged; Aged, 80 and over; Autoanalysis; Brain; Cocaine; Cohort Studies; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Head; Humans; Image Interpretation, Computer-Assisted; Iodine Radioisotopes; Parkinson Disease; Radiopharmaceuticals; Software; Tomography, Emission-Computed, Single-Photon | 2007 |
Selective hyposmia and nigrostriatal dopaminergic denervation in Parkinson's disease.
Topics: Aged; Cocaine; Corpus Striatum; Denervation; Dopamine; Dopamine Uptake Inhibitors; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neural Pathways; Olfaction Disorders; Parkinson Disease; Positron-Emission Tomography; Substantia Nigra | 2007 |
Human retinal pigment epithelial cell implants ameliorate motor deficits in two rat models of Parkinson disease.
Topics: Analysis of Variance; Animals; Autoradiography; Cell Transplantation; Cocaine; Corpus Striatum; Disease Models, Animal; Dopamine Uptake Inhibitors; Extremities; Functional Laterality; Humans; Male; Motor Neuron Disease; Parkinson Disease; Pigment Epithelium of Eye; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Time Factors; Transplantation, Heterologous | 2007 |
Grooved pegboard test as a biomarker of nigrostriatal denervation in Parkinson's disease.
Topics: Aged; Biomarkers; Cocaine; Female; Humans; Isotopes; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Parkinson Disease; Positron-Emission Tomography; Psychomotor Performance; Striatonigral Degeneration | 2007 |
Metabolic-dopaminergic mapping of the 6-hydroxydopamine rat model for Parkinson's disease.
Topics: Animals; Behavior, Animal; Cocaine; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Fluorodeoxyglucose F18; Glucose; Humans; Oxidopamine; Parkinson Disease; Positron-Emission Tomography; Rats; Rats, Wistar; Tyrosine 3-Monooxygenase | 2008 |
Importance of low-range CAG expansion and CAA interruption in SCA2 Parkinsonism.
Topics: Aged; Alleles; Ataxins; Cocaine; Dopamine; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Mutation; Neostriatum; Nerve Tissue Proteins; Parkinson Disease; Pedigree; Phenotype; Positron-Emission Tomography; Raclopride; Radiopharmaceuticals; Reverse Transcriptase Polymerase Chain Reaction; Spinocerebellar Ataxias; Substantia Nigra; Tomography, Emission-Computed, Single-Photon; Trinucleotide Repeats | 2007 |
Loss of thalamic serotonin transporters in early drug-naïve Parkinson's disease patients is associated with tremor: an [(123)I]beta-CIT SPECT study.
Topics: Adult; Aged; Analysis of Variance; Cocaine; Female; Follow-Up Studies; Humans; Male; Middle Aged; Parkinson Disease; Radiopharmaceuticals; Serotonin Plasma Membrane Transport Proteins; Thalamus; Tomography, Emission-Computed, Single-Photon; Tremor | 2008 |
Neurokinin B/NK3 receptors exert feedback inhibition on L-DOPA actions in the 6-OHDA lesion rat model of Parkinson's disease.
Topics: Animals; Antiparkinson Agents; Autoradiography; Behavior, Animal; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cocaine; Disease Models, Animal; Dopamine; Feedback; Functional Laterality; Gene Expression Regulation; Levodopa; Oxidopamine; Parkinson Disease; Peptide Fragments; Quinolines; Radioisotopes; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-3; Serine; Substance P; Sympatholytics; Tyrosine 3-Monooxygenase | 2008 |
Decrease in [3H]cocaine binding to the dopamine transporter in Parkinson's disease.
Topics: Aged; Cocaine; Humans; In Vitro Techniques; Parkinson Disease; Putamen; Receptors, Dopamine | 1983 |
Decreased single-photon emission computed tomographic [123I]beta-CIT striatal uptake correlates with symptom severity in Parkinson's disease.
Topics: Adult; Aged; Cocaine; Corpus Striatum; Female; Humans; Iodine Radioisotopes; Male; Middle Aged; Parkinson Disease; Tomography, Emission-Computed, Single-Photon | 1995 |
Imaging of serotonin and dopamine transporters in the living human brain.
Topics: Adult; Brain; Brain Chemistry; Carrier Proteins; Cocaine; Depressive Disorder; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Panic Disorder; Parkinson Disease; Schizophrenia; Serotonin; Serotonin Plasma Membrane Transport Proteins; Tomography, Emission-Computed, Single-Photon | 1995 |
PET studies on brain monoamine transporters with carbon-11-beta-CIT in Parkinson's disease.
Topics: Adult; Aged; Brain; Carbon Radioisotopes; Caudate Nucleus; Cerebellum; Cocaine; Dopamine; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Putamen; Serotonin; Thalamus; Tomography, Emission-Computed | 1995 |
On-off effects of dopamine receptor agonists in the hemi-parkinsonian rat.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Bromocriptine; Cocaine; Dopamine Agents; Dose-Response Relationship, Drug; Female; Injections, Intraperitoneal; Motor Activity; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley | 1993 |
SPECT imaging of dopamine and serotonin transporters with [123I]beta-CIT. Binding kinetics in the human brain.
Topics: Adult; Aged; Brain; Carrier Proteins; Cocaine; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Parkinson Disease; Protein Binding; Serotonin Plasma Membrane Transport Proteins; Tomography, Emission-Computed, Single-Photon | 1993 |
11C-WIN 35,428 for detecting dopamine depletion in mild Parkinson's disease.
Topics: Carbon Radioisotopes; Cocaine; Dopamine; Humans; Parkinson Disease; Tomography, Emission-Computed | 1994 |
Clinical and preclinical PET correlates of parkinsonism with 11C-WIN 35,428.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Carbon Radioisotopes; Cocaine; Humans; Parkinson Disease; Parkinson Disease, Secondary; Tomography, Emission-Computed | 1994 |
Initial experience with single-photon emission tomography using iodine-123-labelled 2 beta-carbomethoxy-3 beta-(4-iodophenyl) tropane in human brain.
Topics: Aged; Basal Ganglia; Brain; Cocaine; Humans; Iodine Radioisotopes; Middle Aged; Parkinson Disease; Reference Values; Thalamus; Tomography, Emission-Computed, Single-Photon | 1993 |
Single photon emission computed tomographic imaging demonstrates loss of striatal dopamine transporters in Parkinson disease.
Topics: Adult; Aged; Antiparkinson Agents; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Iodine Radioisotopes; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Reference Values; Tomography, Emission-Computed, Single-Photon | 1993 |
Positron emission tomographic imaging of the dopamine transporter with 11C-WIN 35,428 reveals marked declines in mild Parkinson's disease.
Topics: Biomarkers; Brain; Carbon Radioisotopes; Carrier Proteins; Caudate Nucleus; Cerebellum; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Mesencephalon; Middle Aged; Nerve Tissue Proteins; Organ Specificity; Parkinson Disease; Putamen; Tomography, Emission-Computed | 1993 |
PET examination of the monoamine transporter with [11C]beta-CIT and [11C]beta-CFT in early Parkinson's disease.
Topics: Adult; Biological Transport; Brain; Carbon Radioisotopes; Cocaine; Female; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Neuropeptides; Parkinson Disease; Time Factors; Tissue Distribution; Tomography, Emission-Computed; Vesicular Biogenic Amine Transport Proteins | 1995 |
Comparative nigrostriatal dopaminergic imaging with iodine-123-beta CIT-FP/SPECT and fluorine-18-FDOPA/PET.
Topics: Adult; Aged; Aging; Carrier Proteins; Cocaine; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 1996 |
Preparation and biological evaluation of iodine-125-IACFT: a selective SPECT agent for imaging dopamine transporter sites.
Topics: Animals; Autoradiography; Brain; Carrier Proteins; Citalopram; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Iodine Radioisotopes; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Parkinson Disease; Saimiri; Selective Serotonin Reuptake Inhibitors; Tomography, Emission-Computed, Single-Photon | 1996 |
Imaging of dopamine transporters with iodine-123-beta-CIT and SPECT in Parkinson's disease.
Topics: Adult; Aged; Aged, 80 and over; Carrier Proteins; Cocaine; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Receptors, Presynaptic; Tomography, Emission-Computed, Single-Photon | 1997 |
SPECT imaging of dopamine transporter sites in normal and MPTP-Treated rhesus monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Binding Sites; Carrier Proteins; Cocaine; Contrast Media; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Iodine Radioisotopes; Macaca mulatta; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Nortropanes; Parkinson Disease; Parkinson Disease, Secondary; Tissue Distribution; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 1997 |
Parkinsonism associated with long-term cocaine abuse.
Topics: Adult; Cocaine; Humans; Male; Parkinson Disease; Substance-Related Disorders | 1997 |
Practical benefit of [123I]FP-CIT SPET in the demonstration of the dopaminergic deficit in Parkinson's disease.
Topics: Brain; Carrier Proteins; Case-Control Studies; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Radionuclide Imaging; Receptors, Dopamine; Tropanes | 1997 |
SPET investigations in extrapyramidal diseases using specific ligands.
Topics: Adult; Aged; Benzamides; Brain; Cocaine; Dopamine Antagonists; Hepatolenticular Degeneration; Humans; Huntington Disease; Iodine Radioisotopes; Male; Middle Aged; Movement Disorders; Parkinson Disease; Pyrrolidines; Receptors, Dopamine D2; Reference Values; Supranuclear Palsy, Progressive; Tissue Distribution; Tomography, Emission-Computed, Single-Photon | 1997 |
Measurement of the dopaminergic degeneration in Parkinson's disease with [123I] beta-CIT and SPECT. Correlation with clinical findings and comparison with multiple system atrophy and progressive supranuclear palsy.
Topics: Adult; Aged; Brain; Cerebellum; Cocaine; Corpus Striatum; Dopamine; Female; Functional Laterality; Humans; Iodine Radioisotopes; Male; Middle Aged; Olivopontocerebellar Atrophies; Parkinson Disease; Reference Values; Regression Analysis; Supranuclear Palsy, Progressive; Tomography, Emission-Computed, Single-Photon | 1997 |
Brain perfusion scintigraphy with 99mTc-HMPAO or 99mTc-ECD and 123I-beta-CIT single-photon emission tomography in dementia of the Alzheimer-type and diffuse Lewy body disease.
Topics: Aged; Alzheimer Disease; Brain; Carrier Proteins; Case-Control Studies; Cocaine; Cysteine; Dementia; Diagnosis, Differential; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Organotechnetium Compounds; Oximes; Parkinson Disease; Technetium Tc 99m Exametazime; Tomography, Emission-Computed, Single-Photon | 1997 |
Nigrostriatal dopaminergic imaging with iodine-123-beta CIT-FP/SPECT and fluorine-18-FDOPA/PET.
Topics: Aging; Carrier Proteins; Cocaine; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Fluorine Radioisotopes; Humans; Iodine Radioisotopes; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Parkinson Disease; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 1997 |
Nigro-striatal degeneration demonstrated in parkinsonian patients with iodine-123-beta-CIT SPECT: methods of quantitation.
Topics: Aged; Case-Control Studies; Caudate Nucleus; Cocaine; Corpus Striatum; Female; Humans; Iodine Radioisotopes; Linear Models; Male; Middle Aged; Nerve Degeneration; Neural Pathways; Parkinson Disease; Putamen; Substantia Nigra; Tomography, Emission-Computed, Single-Photon | 1997 |
[123I]beta-CIT single-photon emission tomography in Parkinson's disease reveals a smaller decline in dopamine transporters with age than in controls.
Topics: Adult; Aged; Aging; Brain; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Tomography, Emission-Computed, Single-Photon | 1997 |
Test/retest reproducibility of iodine-123-betaCIT SPECT brain measurement of dopamine transporters in Parkinson's patients.
Topics: Adult; Aged; Brain; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Putamen; Reproducibility of Results; Tomography, Emission-Computed, Single-Photon | 1997 |
Positron emission tomography radioligands for dopamine transporters and studies in human and nonhuman primates.
Topics: Animals; Brain; Carbon Radioisotopes; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Methylphenidate; Nerve Tissue Proteins; Parkinson Disease; Primates; Radioligand Assay; Radiopharmaceuticals; Reference Values; Substance-Related Disorders; Tomography, Emission-Computed | 1998 |
Single photon emission computed tomography imaging of dopaminergic function: presynaptic transporter, postsynaptic receptor, and "intrasynaptic" transmitter.
Topics: Animals; Benzamides; Brain; Carrier Proteins; Cocaine; Dopamine; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Humans; Iodine Radioisotopes; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Parkinson Disease; Presynaptic Terminals; Primates; Pyrrolidines; Receptors, Dopamine; Reference Values; Schizophrenia; Serotonin; Serotonin Plasma Membrane Transport Proteins; Synapses; Tomography, Emission-Computed, Single-Photon | 1998 |
SPECT-evaluation of the monoamine uptake site ligand [123I](1R)-2-beta-carbomethoxy-3-beta-(4-iodophenyl)-tropane ([123I]beta-CIT) in untreated patients with suspicion of Parkinson disease.
Topics: Adult; Aged; Basal Ganglia; Carrier Proteins; Cerebellum; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Iodine Radioisotopes; Ligands; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Tomography, Emission-Computed, Single-Photon | 1997 |
Impaired locomotion and dopamine signaling in retinoid receptor mutant mice.
Topics: Animals; Cocaine; Corpus Striatum; Dimerization; Dopamine; Locomotion; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Muscle, Skeletal; Parkinson Disease; Peripheral Nervous System; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Retinoic Acid; Retinoid X Receptors; Schizophrenia; Signal Transduction; Transcription Factors | 1998 |
Drug-naive patients with Parkinson's disease in Hoehn and Yahr stages I and II show a bilateral decrease in striatal dopamine transporters as revealed by [123I]beta-CIT SPECT.
Topics: Adult; Aged; Carrier Proteins; Case-Control Studies; Cocaine; Corpus Striatum; Discriminant Analysis; Disease Progression; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Functional Laterality; Humans; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Tomography, Emission-Computed, Single-Photon | 1998 |
[123I]beta-CIT SPECT visualizes dopamine transporter loss in de novo parkinsonian patients.
Topics: Adult; Aged; Carrier Proteins; Case-Control Studies; Cocaine; Dopamine Plasma Membrane Transport Proteins; Female; Gamma Cameras; Humans; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Tomography, Emission-Computed, Single-Photon | 1998 |
Altropane, a SPECT or PET imaging probe for dopamine neurons: III. Human dopamine transporter in postmortem normal and Parkinson's diseased brain.
Topics: Aged; Brain; Brain Chemistry; Carrier Proteins; Cocaine; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Iodine Radioisotopes; Ligands; Male; Membrane Glycoproteins; Membrane Transport Proteins; Neostriatum; Nerve Tissue Proteins; Parkinson Disease; Putamen; Radioligand Assay; Receptors, Dopamine D1; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 1998 |
123I-beta-CIT and 123I-IBZM-SPECT scanning in levodopa-naive Parkinson's disease.
Topics: Aged; Benzamides; Carrier Proteins; Cerebellum; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Pyrrolidines; Receptors, Dopamine D2; Tomography, Emission-Computed, Single-Photon | 1998 |
Differential distribution of striatal [123I]beta-CIT in Parkinson's disease and progressive supranuclear palsy, evaluated with single-photon emission tomography.
Topics: Aged; Basal Ganglia; Cocaine; Diagnosis, Differential; Female; Humans; Iodine Radioisotopes; Male; Middle Aged; Parkinson Disease; Supranuclear Palsy, Progressive; Tomography, Emission-Computed, Single-Photon | 1998 |
Iodine-123-beta-CIT and iodine-123-FPCIT SPECT measurement of dopamine transporters in healthy subjects and Parkinson's patients.
Topics: Aged; Carrier Proteins; Case-Control Studies; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Parkinson Disease; Time Factors; Tomography, Emission-Computed, Single-Photon; Tropanes | 1998 |
Significance of nonuniform attenuation correction in quantitative brain SPECT imaging.
Topics: Adult; Brain; Case-Control Studies; Cobalt Radioisotopes; Cocaine; Female; Humans; Image Processing, Computer-Assisted; Immobilization; Iodine Radioisotopes; Male; Middle Aged; Parkinson Disease; Phantoms, Imaging; Tomography, Emission-Computed, Single-Photon | 1998 |
PET imaging of the pre-synaptic dopamine uptake sites in rapid-onset dystonia-parkinsonism (RDP).
Topics: Adult; Aged; Brain Mapping; Carbon Radioisotopes; Cocaine; Corpus Striatum; Diagnosis, Differential; Dopamine; Dopamine Uptake Inhibitors; Dystonia; Female; Homovanillic Acid; Humans; Male; Middle Aged; Parkinson Disease; Parkinson Disease, Secondary; Pilot Projects; Receptors, Dopamine; Receptors, Presynaptic; Tomography, Emission-Computed | 1999 |
[123I]beta-CIT and SPECT in essential tremor and Parkinson's disease.
Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Cocaine; Diagnosis, Differential; Female; Humans; Iodine Radioisotopes; Male; Middle Aged; Parkinson Disease; Radioligand Assay; Reference Values; Tomography, Emission-Computed, Single-Photon; Tremor | 1998 |
Striatal uptake of a novel PET ligand, [18F]beta-CFT, is reduced in early Parkinson's disease.
Topics: Aged; Animals; Caudate Nucleus; Cocaine; Dopamine Uptake Inhibitors; Female; Fluorine Radioisotopes; Humans; Male; Middle Aged; Parkinson Disease; Putamen; Tomography, Emission-Computed | 1999 |
Functional morphometry of the striatum in Parkinson's disease on three-dimensional surface display of 123I-beta-CIT SPECT data.
Topics: Carrier Proteins; Case-Control Studies; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Image Processing, Computer-Assisted; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Tomography, Emission-Computed, Single-Photon | 1999 |
PET imaging of the dopamine transporter in progressive supranuclear palsy and Parkinson's disease.
Topics: Carbon Radioisotopes; Carrier Proteins; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Supranuclear Palsy, Progressive; Tomography, Emission-Computed | 1999 |
SPECT measurement of iodine-123-beta-CIT binding to dopamine and serotonin transporters in Parkinson's disease: correlation with symptom severity.
Topics: Adult; Aged; Aged, 80 and over; Carrier Proteins; Cocaine; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Hypothalamus; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Serotonin Plasma Membrane Transport Proteins; Severity of Illness Index; Tomography, Emission-Computed, Single-Photon | 1999 |
Alterations in binding site density of dopamine transporter in the striatum, orbitofrontal cortex, and amygdala in early Parkinson's disease: compartment analysis for beta-CFT binding with positron emission tomography.
Topics: Aged; Amygdala; Binding Sites; Brain; Carrier Proteins; Cerebral Cortex; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Frontal Lobe; Humans; Kinetics; Magnetic Resonance Imaging; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Orbit; Parkinson Disease; Radiography; Time Factors; Tomography, Emission-Computed | 1999 |
Dopamine imaging markers and predictive mathematical models for progressive degeneration in Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Aged; Animals; Biomarkers; Cocaine; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Haplorhini; Humans; Macaca fascicularis; Magnetic Resonance Imaging; Male; Models, Biological; Parkinson Disease; Tomography, Emission-Computed; Visual Cortex | 1999 |
External radioactive reference markers in SPECT imaging of the dopamine system.
Topics: Alzheimer Disease; Brain; Carrier Proteins; Case-Control Studies; Cocaine; Cysteine; Dopamine Plasma Membrane Transport Proteins; Humans; Iodine Radioisotopes; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Organotechnetium Compounds; Parkinson Disease; Radiopharmaceuticals; Receptors, Dopamine; Reproducibility of Results; Tomography, Emission-Computed, Single-Photon | 1999 |
Detection of preclinical Parkinson disease in at-risk family members with use of [123I]beta-CIT and SPECT: an exploratory study.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Case-Control Studies; Cocaine; Corpus Striatum; Female; Humans; Iodine Radioisotopes; Male; Middle Aged; Parkinson Disease; Risk; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 1999 |
Presynaptic and postsynaptic dopaminergic binding densities in the nigrostriatal and mesocortical systems in early Parkinson's disease: a double-tracer positron emission tomography study.
Topics: Aged; Benzazepines; Brain; Carbon Radioisotopes; Carrier Proteins; Caudate Nucleus; Cerebellum; Cerebral Cortex; Cocaine; Corpus Striatum; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Functional Laterality; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Putamen; Receptors, Dopamine D1; Reference Values; Substantia Nigra; Tomography, Emission-Computed | 1999 |
Loss of dopamine uptake sites and dopamine D2 receptors in striatonigral degeneration.
Topics: Aged; Autoradiography; Benzamides; Cadaver; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Putamen; Receptors, Dopamine D2; Reference Values; Striatonigral Degeneration | 2000 |
Striatal [123I]beta-CIT SPECT and prefrontal cognitive functions in Parkinson's disease.
Topics: Adult; Aged; Cocaine; Cognition; Corpus Striatum; Female; Humans; Iodine Radioisotopes; Male; Memory, Short-Term; Middle Aged; Neuropsychological Tests; Parkinson Disease; Prefrontal Cortex; Tomography, Emission-Computed, Single-Photon | 2000 |
Progression in Parkinson's disease: a positron emission tomography study with a dopamine transporter ligand [18F]CFT.
Topics: Aged; Antiparkinson Agents; Brain; Carrier Proteins; Caudate Nucleus; Cerebellum; Cocaine; Disease Progression; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Fluorine Radioisotopes; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Putamen; Time Factors; Tomography, Emission-Computed | 2000 |
Relationship between striatal [123I]beta-CIT binding and four major clinical signs in Parkinson's disease.
Topics: Aged; Antiparkinson Agents; Cocaine; Corpus Striatum; Female; Humans; Hypokinesia; Iodine Radioisotopes; Male; Middle Aged; Motor Activity; Parkinson Disease; Regression Analysis; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Tremor | 2000 |
Measuring the progression of idiopathic Parkinson's disease with [123I] beta-CIT SPECT.
Topics: Aged; Aged, 80 and over; Analysis of Variance; Cocaine; Female; Humans; Iodine Radioisotopes; Linear Models; Male; Middle Aged; Parkinson Disease; Pilot Projects; Statistics, Nonparametric; Tomography, Emission-Computed, Single-Photon | 2000 |
[123I]beta-CIT SPECT in multiple system atrophy, progressive supranuclear palsy, and corticobasal degeneration.
Topics: Adult; Aged; Aged, 80 and over; Basal Ganglia; Case-Control Studies; Cerebral Cortex; Cocaine; Diagnosis, Differential; Female; Humans; Image Processing, Computer-Assisted; Iodine Radioisotopes; Male; Middle Aged; Multiple System Atrophy; Neurodegenerative Diseases; Parkinson Disease; Predictive Value of Tests; Radiopharmaceuticals; Supranuclear Palsy, Progressive; Tomography, Emission-Computed, Single-Photon | 2000 |
[(18)F]FDOPA and [(18)F]CFT are both sensitive PET markers to detect presynaptic dopaminergic hypofunction in early Parkinson's disease.
Topics: Aged; Brain; Caudate Nucleus; Cocaine; Dihydroxyphenylalanine; Dopamine; Down-Regulation; Female; Fluorine Radioisotopes; Functional Laterality; Humans; Male; Middle Aged; Parkinson Disease; Positron-Emission Tomography; Predictive Value of Tests; Presynaptic Terminals; Putamen; Synaptic Transmission | 2001 |
SPECT imaging of the dopamine transporter with [(123)I]-beta-CIT reveals marked decline of nigrostriatal dopaminergic function in Parkinson's disease with urinary dysfunction.
Topics: Aged; Carrier Proteins; Caudate Nucleus; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Degeneration; Nerve Tissue Proteins; Neural Pathways; Parkinson Disease; Putamen; Radiopharmaceuticals; Substantia Nigra; Tomography, Emission-Computed, Single-Photon; Urinary Bladder, Neurogenic | 2001 |
Quantitation of neuroreceptors: a need for better SPECT imaging.
Topics: Brain; Cocaine; Gamma Cameras; Humans; Image Processing, Computer-Assisted; Iodine Radioisotopes; Parkinson Disease; Phantoms, Imaging; Radiopharmaceuticals; Reference Values; Reproducibility of Results; Sensory Receptor Cells; Tomography, Emission-Computed, Single-Photon | 2001 |
Dopamine and glutamate induce distinct striatal splice forms of Ania-6, an RNA polymerase II-associated cyclin.
Topics: Alternative Splicing; Amino Acid Sequence; Animals; Cocaine; Corpus Striatum; COS Cells; Cyclin-Dependent Kinases; Cyclins; Dopamine; Gene Expression Regulation; Genes, Immediate-Early; Glutamic Acid; Male; Mice; Molecular Sequence Data; Parkinson Disease; PC12 Cells; Phosphorylation; Rats; Rats, Sprague-Dawley; RNA Polymerase II; Transfection | 2001 |
[123I]beta-CIT SPECT imaging assessment of the rate of Parkinson's disease progression.
Topics: Aged; Caudate Nucleus; Cocaine; Corpus Striatum; Disease Progression; Dominance, Cerebral; Dopamine Plasma Membrane Transport Proteins; Female; Follow-Up Studies; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Neurologic Examination; Parkinson Disease; Putamen; Reference Values; Tomography, Emission-Computed, Single-Photon | 2001 |
[(123)I]beta-CIT SPECT imaging demonstrates reduced density of striatal dopamine transporters in Parkinson's disease and multiple system atrophy.
Topics: Adult; Aged; Aged, 80 and over; Cocaine; Diagnosis, Differential; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Multiple System Atrophy; Nerve Tissue Proteins; Parkinson Disease; Predictive Value of Tests; Radiopharmaceuticals; Severity of Illness Index; Substantia Nigra; Tomography, Emission-Computed, Single-Photon | 2001 |
Rigidity decreases resting tremor intensity in Parkinson's disease: A [(123)I]beta-CIT SPECT study in early, nonmedicated patients.
Topics: Adult; Cocaine; Corpus Striatum; Dominance, Cerebral; Female; Humans; Iodine Radioisotopes; Male; Middle Aged; Muscle Rigidity; Parkinson Disease; Radiopharmaceuticals; Severity of Illness Index; Tomography, Emission-Computed, Single-Photon; Tremor | 2001 |
Severe depletion of cocaine recognition sites associated with the dopamine transporter in Parkinson's-diseased striatum.
Topics: Aged; Autoradiography; Carrier Proteins; Caudate Nucleus; Cocaine; Corpus Striatum; Humans; Parkinson Disease; Putamen; Receptors, Drug; Reference Values; Tritium | 1991 |
[3H]SCH 23390 labeled D1 dopamine receptors are unchanged in schizophrenia and Parkinson's disease.
Topics: Aged; Antipsychotic Agents; Benzazepines; Cocaine; Humans; In Vitro Techniques; Middle Aged; Parkinson Disease; Radioligand Assay; Receptors, Dopamine; Receptors, Dopamine D1; Schizophrenia; Spiperone | 1985 |
Sodium dependent [3H]cocaine binding associated with dopamine uptake sites in the rat striatum and human putamen decrease after dopaminergic denervation and in Parkinsons disease.
Topics: Animals; Binding Sites; Biological Transport; Cocaine; Corpus Striatum; Dopamine; Humans; Hydroxydopamines; In Vitro Techniques; Membrane Transport Proteins; Oxidopamine; Parkinson Disease; Putamen; Rats; Rats, Inbred Strains; Sodium | 1985 |
A neuropsychopharmacological comparison of d-amphetamine, L-dopa and cocaine.
Topics: Animals; Behavior, Animal; Cats; Cocaine; Cortical Synchronization; Dextroamphetamine; Dihydroxyphenylalanine; Electroencephalography; Female; Hair; Humans; Hydrazines; Male; Methyldopa; Paranoid Disorders; Parkinson Disease; Phenethylamines; Reticular Formation; Salivation; Sleep, REM; Stereoisomerism | 1971 |
Pupillary effects of levodopa therapy. Development of anisocoria in latent Horner's syndrome.
Topics: Cocaine; Dihydroxyphenylalanine; Dilatation; Dopamine; Epinephrine; Eye; Eye Diseases; Horner Syndrome; Humans; Male; Middle Aged; Parkinson Disease; Polyradiculopathy; Pupil; Sympathetic Nervous System | 1970 |
L-dopa-induced anisocoria in latent Horner's syndrome.
Topics: Amides; Cocaine; Dihydroxyphenylalanine; Dilatation; Dopamine; Epinephrine; Horner Syndrome; Humans; Parkinson Disease; Phenylephrine; Polyradiculopathy; Propionates; Pupil | 1970 |
Sympathetic deficits following thalamotomy.
Topics: Blepharoptosis; Cocaine; Electrooculography; Humans; Male; Movement Disorders; Parkinson Disease; Postoperative Complications; Pupil; Sweating; Sympathetic Nervous System; Thalamus | 1968 |
Crack cocaine use due to dopamine agonist therapy in Parkinson disease.
Topics: Adult; Aged; Cocaine-Related Disorders; Crack Cocaine; Dopamine Agonists; Humans; Male; Middle Aged; Parkinson Disease | 2013 |
Parkinson's disease risks associated with cigarette smoking, alcohol consumption, and caffeine intake.
Topics: Adult; Aged; Alcohol Drinking; Caffeine; Case-Control Studies; Coffee; Cola; Female; Humans; Male; Middle Aged; Odds Ratio; Parkinson Disease; Parkinson Disease, Secondary; Phosphodiesterase Inhibitors; Population Surveillance; Risk Assessment; Risk Factors; Smoking; Tea; Washington | 2002 |
Wet voice as a sign of penetration/aspiration in Parkinson's disease: does testing material matter?
Topics: Aged; Beverages; Candy; Deglutition; Endoscopes; Female; Humans; Male; Middle Aged; Optical Fibers; Parkinson Disease; Phonation; Predictive Value of Tests; Prospective Studies; Respiratory Aspiration; Saliva; Sensitivity and Specificity; Single-Blind Method; Viscosity; Voice Disorders; Voice Quality; Water; Yogurt | 2014 |