cocaine has been researched along with Hyperactivity, Motor in 81 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (6.17) | 18.7374 |
| 1990's | 10 (12.35) | 18.2507 |
| 2000's | 40 (49.38) | 29.6817 |
| 2010's | 21 (25.93) | 24.3611 |
| 2020's | 5 (6.17) | 2.80 |
| Authors | Studies |
|---|---|
| Shang, L; Wei, H; Zhan, CG; Zheng, F | 1 |
| Bariselli, S; Creed, MC; Kravitz, AV; Miyazaki, NL | 1 |
| Brizzi, A; Carai, MAM; Collu, M; Colombo, G; Corelli, F; Gessa, GL; Lobina, C; Lorrai, I; Maccioni, P; Mugnaini, C; Zaru, A | 1 |
| Aguilar, MA; Ledesma, JC; Manzanedo, C | 1 |
| Deng, J; Kim, K; Shang, L; Zhan, CG; Zheng, F; Zheng, X | 1 |
| Conn, PJ; Dall, C; Dencker, D; Fink-Jensen, A; Molander, AC; Thomsen, M; Weikop, P; Wörtwein, G | 1 |
| Berezniuk, I; Fricker, LD; Marcus, DJ; Morgan, DJ; Pintar, J; Rodriguiz, RM; Wetsel, WC; Zee, ML | 1 |
| Daumas, S; El Mestikawy, S; Henrion, A; Jamain, S; Poirel, O; Ramet, L; Sakae, DY | 1 |
| Canseco-Alba, A; Lin, Z; Liu, QR; Onaivi, ES; Sanabria, B; Schanz, N; Zhao, J | 1 |
| Jang, H; Jang, JK; Kim, JH; Kim, WY; Lee, JW | 1 |
| Davis, DC; Fan, KH; Lever, JR; Lever, SZ; Miller, DK; Nahas, RI; Oelrichs, CE; Sage, AS | 1 |
| Andersen, ML; Berro, LF; Costa, JM; Frussa-Filho, R; Fukushiro, DF; Grapiglia, SB; Hollais, AW; Mári-Kawamoto, E; Patti, CL; Santos, R; Trombin, TF; Tufik, S; Wuo-Silva, R | 1 |
| Carmack, TL; Fergason-Cantrell, EA; Green, CL; Lever, JR; Lever, SZ; Miller, DK; Watkinson, LD | 1 |
| Fink-Jensen, A; Galli, A; Graham, DL; Reddy, IA; Stanwood, GD; Sørensen, G; Weikop, P; Wortwein, G | 1 |
| Appavu, R; Chen, H; Cunningham, KA; Ding, C; Ding, Y; Neelakantan, H; Rudra, JS; Snook, JD; Stutz, S; Zhou, J | 1 |
| Baldaia, MA; Berro, LF; Frussa-Filho, R; Hollais, AW; Marinho, E; Oliveira-Lima, AJ; Ribeiro, LT; Santos-Baldaia, R; Talhati, F; Wuo-Silva, R | 1 |
| Boyer, F; Dreyer, JL | 1 |
| Jang, JK; Kim, JH; Yoon, HS | 1 |
| Carey, RJ; Huston, JP; Müller, CP; Pum, ME | 1 |
| Delair, B; Foulon, C; Lempereur, N; Maurice, T; Melnyk, P; Toussaint, M; Vaccher, C | 1 |
| Miller, JS; Tallarida, RJ; Unterwald, EM | 1 |
| Adams, W; Ayton, S; van den Buuse, M | 1 |
| Brookshire, BR; Budygin, EA; Goldowitz, D; Hamre, K; Jones, SR; Mathews, TA | 1 |
| Angst, MJ; Brasse, D; Guiberteau, T; Macedo, CE; O'Brien, TJ; Sandner, G | 1 |
| Kim, JH; Kim, WY; Yoon, HS | 1 |
| Griggs, R; Koeltzow, TE; Wayman, W; Weir, C | 1 |
| Barros, HM; de Azeredo, LA; Frazzon, AP; Marquardt, AR | 1 |
| Brabant, C; Kuschpel, AS; Picciotto, MR | 1 |
| Alvarez, VA; Bello, EP; Gelman, DM; Lovinger, DM; Low, MJ; Mateo, Y; Noaín, D; Rubinstein, M; Shin, JH | 1 |
| Caine, SB; Thomsen, M | 1 |
| Bengtsen, CH; Christiansen, SH; Dencker, D; Fink-Jensen, A; Jensen, M; Loland, CJ; Petersen, JH; Sørensen, G; Weikop, P; Woldbye, DP; Wörtwein, G | 1 |
| Biederer, T; Giza, JI; Jeffrey, RA; Jung, Y; Neugebauer, NM; Picciotto, MR | 1 |
| Barrot, M; Bockaert, J; Charnay, Y; Compan, V; Dusticier, N; Jean, A; Laurent, L; Neve, R; Nieoullon, A | 1 |
| Czepiel, K; Filip, M; Papla, I; Przegaliński, E | 1 |
| Choi, SW; Elmaleh, DR; Fischman, AJ; Hanson, RN; Shoup, TM | 1 |
| Beemster, P; Schoffelmeer, AN; Vanderschuren, LJ | 1 |
| Brabant, C; Tambour, S; Tirelli, E | 1 |
| Boules, M; Fauq, A; McCormick, D; McMahon, B; Richelson, E; Stewart, J; Wang, R; Warrington, L; Yerbury, S | 1 |
| Filip, M; Papla, I; Przegaliński, E; Siwanowicz, J | 1 |
| Bubar, MJ; Cunningham, KA; Filip, M | 1 |
| Bert, B; Carey, RJ; De Souza Silva, MA; Fink, H; Huston, JP; Müller, CP; Thönnessen, H | 1 |
| Barros, M; Carey, RJ; Huston, JP; Müller, CP; Thönnessen, H; Tomaz, C | 1 |
| Cassel, JC; Cosquer, B; Galani, R; Jeltsch, H; Lazarus, C | 1 |
| Biala, G | 1 |
| Bonito-Oliva, A; Cabib, S; Conversi, D; Orsini, C | 1 |
| Clifton, PG; Hartfield, AW; Moore, NA | 1 |
| Edwards, S; Fuller, DC; Orsulak, PJ; Self, DW; Whisler, KN | 1 |
| Carta, M; Collu, M; Fadda, F; Stancampiano, R | 1 |
| Cryan, JF; Kaupmann, K; Lhuillier, L; Mombereau, C | 1 |
| Branch, MN; Pinkston, JW | 1 |
| Bedogni, F; Collu, M; Fadda, P; Fresu, A; Racagni, G; Riva, MA | 1 |
| Constales, C; Miller, DK; Putnam, WC; Rodvelt, KR | 1 |
| Elliott, AE; Hollas, CN; Wellman, PJ | 1 |
| Cabral, H; López-Patiño, MA; Yu, L; Zhdanova, IV | 1 |
| Guimarães, FS; Leite, JV; Moreira, FA | 1 |
| Afshari, LK; Azam, M; Bidja, AH; Feeney, RB; Pagán, OR; Rowlands, AL; Roy, DM; Urban, KR | 1 |
| Atack, JR; Dawson, GR; Morris, HV; Reynolds, DS; Rosahl, TW; Stephens, DN | 1 |
| Chermat, R; Kloczko, J; Puech, AJ; Simon, P; Soubrie, P; Thiebot, MH | 1 |
| Barr, GA; Bridger, WH; Cooper, S; Paredes, W; Schiff, SR; Sharpless, NS | 1 |
| Cooper, DC; Graybiel, AM; Hu, XT; Moratalla, R; Tonegawa, S; White, FJ; Xu, M | 1 |
| Alexander, GJ; Chatterjie, N; Lieberman, KW; Sechzer, JA | 1 |
| Caron, MG; Giros, B; Jaber, M; Jones, S | 1 |
| Hagan, J; Hatcher, JP; Lewis, VA; Reavill, C; Sanger, GJ | 1 |
| Cunningham, KA; McCreary, AC | 1 |
| Cailhol, S; Mormède, P | 1 |
| Cunningham, KA; De La Garza, R | 1 |
| Druhan, JP; Franklin, TR | 1 |
| Tirelli, E | 1 |
| Abumrad, NN; Ahmed, N; Gatley, J; Molina, PE; Volkow, ND | 1 |
| Garland, T; Girard, I; Hosack, GR; Kelley, AE; Mitchell, GS; Rhodes, JS | 1 |
| Blanc, G; Drouin, C; Glowinski, J; Tassin, JP; Villégier, AS | 1 |
| Hayase, T; Yamamoto, K; Yamamoto, Y | 1 |
| Cunningham, KA; Filip, M | 1 |
| Diaz, J; Francès, H; Le Foll, B; Schwartz, JC; Sokoloff, P | 1 |
| Ball, DM; Jackson, HC; Nutt, DJ | 1 |
| Henderson, MG; McMillen, BA | 1 |
| Costello, M; Nutt, DJ; Post, RM; Tandeciarz, S; Weiss, SR | 1 |
| Koob, GF; Pulvirenti, L; Swerdlow, NR | 1 |
| Knudsen, F; Krogh, B; Schou, H | 1 |
| Ladisich, W; Matussek, N; Volbehr, H | 1 |
| Guthrie, HA; Krummel, DA; Seligson, FH | 1 |
3 review(s) available for cocaine and Hyperactivity, Motor
| Article | Year |
|---|---|
[Behavioral and pharmacological characteristics of mice lacking the dopamine transporter].
Topics: Adaptation, Physiological; Amphetamines; Animals; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Cocaine; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Humans; Hyperkinesis; Mice; Mice, Knockout; Morphine; Narcotics | 2004 |
The dopamine transporter: a crucial component regulating dopamine transmission.
Topics: Amphetamines; Animals; Brain; Carrier Proteins; Central Nervous System Stimulants; Cocaine; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Gene Dosage; Genotype; Homeostasis; Humans; Hyperkinesis; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Knockout; Mice, Transgenic; Nerve Tissue Proteins; Parkinson Disease; Phenotype; Rats; Schizophrenia; Substance-Related Disorders | 1997 |
Hyperactivity: is candy causal?
Topics: Attention Deficit Disorder with Hyperactivity; Cacao; Caffeine; Candy; Child; Child, Preschool; Female; Humans; Hyperkinesis; Male; Randomized Controlled Trials as Topic; Sucrose | 1996 |
1 trial(s) available for cocaine and Hyperactivity, Motor
| Article | Year |
|---|---|
Differential sensitivity to acute administration of cocaine, GBR 12909, and fluoxetine in mice selectively bred for hyperactive wheel-running behavior.
Topics: Animals; Animals, Outbred Strains; Breeding; Cocaine; Crosses, Genetic; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Female; Fluoxetine; Hyperkinesis; Injections, Intraperitoneal; Male; Mice; Mice, Inbred ICR; Piperazines | 2001 |
77 other study(ies) available for cocaine and Hyperactivity, Motor
| Article | Year |
|---|---|
Effects of Cebranopadol on Cocaine-induced Hyperactivity and Cocaine Pharmacokinetics in Rats.
Topics: Analgesics; Animals; Behavior, Animal; Cocaine; Dose-Response Relationship, Drug; Hyperkinesis; Indoles; Male; Motor Activity; Rats, Sprague-Dawley; Spiro Compounds | 2020 |
Orbitofrontal-striatal potentiation underlies cocaine-induced hyperactivity.
Topics: Animals; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Corpus Striatum; Disease Models, Animal; Dopamine; Female; Hyperkinesis; Locomotion; Male; Mice; Mice, Inbred C57BL; Neurons; Optogenetics; Prefrontal Cortex | 2020 |
Suppressing effect of the novel positive allosteric modulator of the GABA
Topics: Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Dopamine Uptake Inhibitors; GABA Modulators; Hyperkinesis; Locomotion; Male; Mice; Morphine; Narcotics; Nicotine; Nicotinic Agonists; Receptors, GABA-B | 2021 |
Cannabidiol prevents several of the behavioral alterations related to cocaine addiction in mice.
Topics: Animals; Cannabidiol; Cocaine; Cocaine-Related Disorders; Conditioning, Classical; Dose-Response Relationship, Drug; Extinction, Psychological; Hyperkinesis; Injections, Intraperitoneal; Locomotion; Male; Mice; Mice, Inbred C57BL; Substance Withdrawal Syndrome | 2021 |
Cocaine hydrolase blocks cocaine-induced dopamine transporter trafficking to the plasma membrane.
Topics: Animals; Carboxylic Ester Hydrolases; Cell Membrane; Cocaine; Cocaine-Related Disorders; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Hyperkinesis; Male; Rats; Rats, Sprague-Dawley; Recombinant Proteins | 2022 |
Muscarinic receptor M
Topics: Animals; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Hyperkinesis; Male; Mice; Mice, Knockout; Pyridazines; Pyridines; Reinforcement, Psychology; Reward; Thiophenes | 2017 |
ProSAAS-derived peptides are regulated by cocaine and are required for sensitization to the locomotor effects of cocaine.
Topics: Amphetamine; Animals; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Exploratory Behavior; Female; Gene Expression Regulation; Hyperkinesis; Locomotion; Male; Mass Spectrometry; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Tissue Proteins; Neuropeptides; Nucleus Accumbens; Ventral Tegmental Area | 2017 |
Differential expression of VGLUT3 in laboratory mouse strains: Impact on drug-induced hyperlocomotion and anxiety-related behaviors.
Topics: Amino Acid Transport Systems, Acidic; Animals; Anxiety; Brain; Cocaine; Cocaine-Related Disorders; Hyperkinesis; Locomotion; Male; Maze Learning; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA | 2019 |
Behavioral effects of psychostimulants in mutant mice with cell-type specific deletion of CB2 cannabinoid receptors in dopamine neurons.
Topics: Amphetamine; Animals; Cannabinoids; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Eukaryotic Initiation Factor-3; Gene Expression Regulation; Hyperkinesis; Locomotion; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nicotine; Receptor, Cannabinoid, CB2; RNA, Messenger; Statistics, Nonparametric; Time Factors; Tyrosine 3-Monooxygenase | 2019 |
Decrease of GSK3β phosphorylation in the rat nucleus accumbens core enhances cocaine-induced hyper-locomotor activity.
Topics: Animals; Cocaine; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hyperkinesis; Male; Motor Activity; Nucleus Accumbens; Phosphorylation; Rats; Rats, Sprague-Dawley; Up-Regulation | 2013 |
Effects of N-phenylpropyl-N'-substituted piperazine sigma receptor ligands on cocaine-induced hyperactivity in mice.
Topics: Animals; Cocaine; Dose-Response Relationship, Drug; Hyperkinesis; Ligands; Male; Mice; Piperazines; Receptors, sigma | 2013 |
Acute total sleep deprivation potentiates cocaine-induced hyperlocomotion in mice.
Topics: Animals; Central Nervous System Stimulants; Cocaine; Hyperkinesis; Male; Mice; Sleep Deprivation | 2014 |
Relationship between cerebral sigma-1 receptor occupancy and attenuation of cocaine's motor stimulatory effects in mice by PD144418.
Topics: Animals; Binding Sites; Cocaine; Dopamine Plasma Membrane Transport Proteins; Guinea Pigs; Hyperkinesis; Isoxazoles; Locomotion; Male; Mice; Motor Cortex; Narcotic Antagonists; Norepinephrine Plasma Membrane Transport Proteins; Protein Binding; Pyridines; Receptors, sigma; Serotonin Plasma Membrane Transport Proteins; Sigma-1 Receptor | 2014 |
The glucagon-like peptide 1 (GLP-1) receptor agonist exendin-4 reduces cocaine self-administration in mice.
Topics: Analysis of Variance; Animals; Benzazepines; Cocaine; Corpus Striatum; Dopamine; Dopamine Agonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Exenatide; Exploratory Behavior; Gene Expression Regulation; Hyperkinesis; Hypoglycemic Agents; Male; Mice; Microdialysis; Motor Activity; Peptides; Proto-Oncogene Proteins c-fos; Self Administration; Time Factors; Venoms | 2015 |
Suppression of Cocaine-Evoked Hyperactivity by Self-Adjuvanting and Multivalent Peptide Nanofiber Vaccines.
Topics: Adjuvants, Pharmaceutic; Animals; Cocaine; Dose-Response Relationship, Drug; Hyperkinesis; Locomotion; Male; Mice; Mice, Inbred C57BL; Nanofibers; Vaccines, Subunit | 2016 |
Context-dependent efficacy of a counter-conditioning strategy with atypical neuroleptic drugs in mice previously sensitized to cocaine.
Topics: Animals; Antipsychotic Agents; Aripiprazole; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Exploratory Behavior; Hyperkinesis; Locomotion; Male; Mice; Piperazines; Statistics, Nonparametric; Thiazoles | 2017 |
The role of gamma-synuclein in cocaine-induced behaviour in rats.
Topics: Animals; Behavior, Animal; Brain; Cell Line; Cocaine; Cocaine-Related Disorders; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Down-Regulation; gamma-Synuclein; Gene Silencing; Genetic Vectors; Humans; Hyperkinesis; Lentivirus; Male; Rats; Rats, Wistar; RNA, Messenger; RNA, Small Interfering | 2008 |
Blockade of group II metabotropic glutamate receptors produces hyper-locomotion in cocaine pre-exposed rats by interactions with dopamine receptors.
Topics: Amino Acids; Animals; Behavior, Animal; Benzazepines; Cocaine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Hyperkinesis; Male; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Metabotropic Glutamate; Salicylamides; Xanthenes | 2008 |
Role of medial prefrontal, entorhinal, and occipital 5-HT in cocaine-induced place preference and hyperlocomotion: evidence for multiple dissociations.
Topics: 5,7-Dihydroxytryptamine; Animals; Association Learning; Behavior, Animal; Cocaine; Conditioning, Classical; Dopamine Uptake Inhibitors; Entorhinal Cortex; Hippocampus; Hyperkinesis; Male; Microinjections; Occipital Lobe; Prefrontal Cortex; Rats; Rats, Wistar; Serotonin; Stereotyped Behavior | 2008 |
Tic hydantoin sigma-1 agonist: pharmacological characterization on cocaine-induced stimulant and appetitive effects.
Topics: Analysis of Variance; Animals; Appetitive Behavior; Behavior, Animal; Cellulose, Oxidized; Chromatography, High Pressure Liquid; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Enzyme Inhibitors; Ethylenediamines; Extinction, Psychological; Hydantoins; Hyperkinesis; Locomotion; Male; Mice; Protein Binding; Receptors, sigma; Time Factors | 2009 |
Cocaine-induced hyperactivity and sensitization are dependent on GSK3.
Topics: Animals; Caudate Nucleus; Cocaine; Cocaine-Related Disorders; Enzyme Activation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hyperkinesis; Indoles; Locomotion; Male; Maleimides; Mice; Phosphorylation; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Putamen; Stereotyped Behavior; Valproic Acid | 2009 |
Serotonergic lesions of the dorsal hippocampus differentially modulate locomotor hyperactivity induced by drugs of abuse in rats: implications for schizophrenia.
Topics: 5,7-Dihydroxytryptamine; Amphetamines; Animals; Cocaine; Disease Models, Animal; Dose-Response Relationship, Drug; Hippocampus; Hyperkinesis; Ketamine; Male; Phencyclidine; Rats; Rats, Sprague-Dawley; Schizophrenia; Serotonin | 2009 |
Ethanol-induced hyperactivity is associated with hypodopaminergia in the 22-TNJ ENU-mutated mouse.
Topics: Animals; Caudate Nucleus; Cocaine; Dopamine; Ethanol; Ethylnitrosourea; Hyperkinesis; Mice; Mice, Mutant Strains; Microdialysis; Models, Animal; Motor Activity; Nucleus Accumbens; Putamen; Quinpirole; Receptors, Dopamine D2 | 2009 |
Acoustic hypersensitivity in adult rats after neonatal ventral hippocampus lesions.
Topics: Acoustic Stimulation; Age Factors; Amphetamine; Analysis of Variance; Animals; Auditory Pathways; Cocaine; Electrodes, Implanted; Electroencephalography; Evoked Potentials, Auditory, Brain Stem; Hippocampus; Hyperkinesis; Ibotenic Acid; Magnetic Resonance Imaging; Male; Motor Activity; Neuronal Plasticity; Rats; Rats, Sprague-Dawley; Reflex, Startle; Staining and Labeling | 2010 |
Microinjection of CART peptide 55-102 into the nucleus accumbens core inhibits the expression of conditioned hyperactivity in a cocaine-associated environment.
Topics: Analysis of Variance; Animals; Behavior, Animal; Cocaine; Conditioning, Classical; Drug Interactions; Hyperkinesis; Male; Microinjections; Motor Activity; Nerve Tissue Proteins; Nucleus Accumbens; Peptide Fragments; Rats; Rats, Sprague-Dawley | 2010 |
Intermittent methylphenidate during adolescent development produces locomotor hyperactivity and an enhanced response to cocaine compared to continuous treatment in rats.
Topics: Age Factors; Animals; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Exploratory Behavior; Hyperkinesis; Male; Maze Learning; Methylphenidate; Rats; Rats, Sprague-Dawley | 2010 |
Cocaine reverses the changes in GABAA subunits and in glutamic acid decarboxylase isoenzymes mRNA expression induced by neonatal 6-hydroxydopamine.
Topics: Animals; Animals, Newborn; Behavior, Animal; Cocaine; Corpus Striatum; Glutamate Decarboxylase; Hippocampus; Hyperkinesis; Isoenzymes; Male; Oxidopamine; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, GABA-A; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sympatholytics | 2010 |
Locomotion and self-administration induced by cocaine in 129/OlaHsd mice lacking galanin.
Topics: Analysis of Variance; Animals; Behavior, Animal; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Galanin; Hyperkinesis; Male; Mice; Mice, 129 Strain; Mice, Knockout; Motor Activity; Random Allocation; Reinforcement, Psychology; Self Administration | 2010 |
Cocaine supersensitivity and enhanced motivation for reward in mice lacking dopamine D2 autoreceptors.
Topics: Analysis of Variance; Animals; Autoradiography; Baclofen; Choice Behavior; Cocaine; Conditioning, Operant; Dihydroxyphenylalanine; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine Uptake Inhibitors; Drug Interactions; Enzyme Inhibitors; Exploratory Behavior; Food; GABA-B Receptor Agonists; Hydrazines; Hyperkinesis; In Vitro Techniques; Maze Learning; Membrane Potentials; Mesencephalon; Mice; Mice, Knockout; Motivation; Motor Activity; Neurons; Quinpirole; Receptors, Dopamine D2; Reinforcement Schedule; Reward; Sulpiride | 2011 |
Psychomotor stimulant effects of cocaine in rats and 15 mouse strains.
Topics: Animals; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Female; Hyperkinesis; Locomotion; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Models, Animal; Motor Activity; Phenotype; Predictive Value of Tests; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration; Sex Factors; Substance-Related Disorders | 2011 |
Neuropeptide Y Y5 receptor antagonism attenuates cocaine-induced effects in mice.
Topics: Animals; Animals, Outbred Strains; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Cyclohexanes; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Drug Interactions; Female; Hyperkinesis; Male; Mice; Mice, Knockout; Nucleus Accumbens; Receptors, Neuropeptide Y; Reinforcement, Psychology; Self Administration; Xanthenes | 2012 |
The synaptic adhesion molecule SynCAM 1 contributes to cocaine effects on synapse structure and psychostimulant behavior.
Topics: Animals; Cell Adhesion Molecule-1; Cell Adhesion Molecules; Central Nervous System Stimulants; Cocaine; Dendritic Spines; Hyperkinesis; Immunoglobulins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nucleus Accumbens; Synapses | 2013 |
The nucleus accumbens 5-HTR₄-CART pathway ties anorexia to hyperactivity.
Topics: Amphetamine; Animals; Anorexia; Cocaine; Hyperkinesis; Male; Mice; Mice, Knockout; N-Methyl-3,4-methylenedioxyamphetamine; Nucleus Accumbens; Piperidines; Propane; Real-Time Polymerase Chain Reaction; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Antagonists | 2012 |
Effects of 5-HT1B receptor ligands microinjected into the accumbal shell or core on the cocaine-induced locomotor hyperactivity in rats.
Topics: Animals; Benzamides; Cocaine; Hyperkinesis; Ligands; Male; Microinjections; Motor Activity; Nucleus Accumbens; Pyridines; Pyrroles; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 2002 |
Novel (bisarylmethoxy)butylpiperidine analogues as neurotransmitter transporter inhibitors with activity at dopamine receptor sites.
Topics: Animals; Cell Line; Cocaine; Cocaine-Related Disorders; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Humans; Hyperkinesis; Ligands; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Motor Activity; Nerve Tissue Proteins; Neurotransmitter Uptake Inhibitors; Piperidines; Radioligand Assay; Rats; Receptors, Dopamine; Receptors, Serotonin; Structure-Activity Relationship | 2002 |
On the role of noradrenaline in psychostimulant-induced psychomotor activity and sensitization.
Topics: Amphetamine-Related Disorders; Animals; Central Nervous System Stimulants; Clonidine; Cocaine; Cocaine-Related Disorders; Dextroamphetamine; Dose-Response Relationship, Drug; Hyperkinesis; Male; Motor Activity; Norepinephrine; Prazosin; Propranolol; Psychomotor Agitation; Rats; Rats, Wistar | 2003 |
Quasi-asymptotic development of conditioned hyperactivity induced by intermittent injections of cocaine in C57BL/6J mice.
Topics: Animals; Cocaine; Conditioning, Operant; Cues; Hyperkinesis; Male; Mice; Mice, Inbred C57BL; Motor Activity; Reinforcement Schedule | 2003 |
Selective tolerance to the hypothermic and anticataleptic effects of a neurotensin analog that crosses the blood-brain barrier.
Topics: Amphetamine; Animals; Behavior, Animal; Blood Glucose; Blood-Brain Barrier; Body Temperature; Brain; Catalepsy; Cocaine; Drug Tolerance; Haloperidol; Hyperkinesis; Hypothermia; Male; Neurotensin; Peptide Fragments; Rats; Rats, Sprague-Dawley; Time Factors | 2003 |
Effects of 5-HT1B receptor ligands microinjected into the ventral tegmental area on the locomotor and sensitizating effects of cocaine in rats.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Behavior, Animal; Benzamides; Cocaine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Hyperkinesis; Male; Microinjections; Motor Activity; Pyridines; Pyrroles; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin Agents; Ventral Tegmental Area | 2004 |
Contribution of serotonin (5-hydroxytryptamine; 5-HT) 5-HT2 receptor subtypes to the hyperlocomotor effects of cocaine: acute and chronic pharmacological analyses.
Topics: Amphetamines; Animals; Cocaine; Drug Interactions; Fluorobenzenes; Hyperkinesis; Indoles; Male; Phenols; Pyrazines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Serotonin Antagonists; Serotonin Receptor Agonists; Thiophenes | 2004 |
Nucleus accumbens serotonin1A receptors control cocaine-induced hyperactivity but not local serotonin increase: an in vivo microdialysis study.
Topics: 3,4-Dihydroxyphenylacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Cocaine; Hydroxyindoleacetic Acid; Hyperkinesis; Male; Microdialysis; Nucleus Accumbens; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin Receptor Agonists | 2004 |
Hippocampus 5-HT(1A)-receptors attenuate cocaine-induced hyperlocomotion and the increase in hippocampal but not nucleus accumbens 5-HT.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Hippocampus; Hyperkinesis; Male; Nucleus Accumbens; Rats; Rats, Wistar; Reaction Time; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin Receptor Agonists; Up-Regulation | 2004 |
No facilitation of amphetamine- or cocaine-induced hyperactivity in adult rats after various 192 IgG-saporin lesions in the basal forebrain.
Topics: Acetylcholinesterase; Amphetamine; Animals; Antibodies, Monoclonal; Basal Nucleus of Meynert; Central Nervous System Stimulants; Cholinergic Agents; Cocaine; Denervation; Dopamine Uptake Inhibitors; Drug Interactions; Hippocampus; Hyperkinesis; Immunotoxins; Injections, Intraventricular; Male; Microinjections; N-Glycosyl Hydrolases; Prosencephalon; Rats; Rats, Long-Evans; Ribosome Inactivating Proteins, Type 1; Saporins; Septum of Brain | 2004 |
Susceptibility to conditioned place preference induced by addictive drugs in mice of the C57BL/6 and DBA/2 inbred strains.
Topics: Analgesics, Opioid; Anesthetics, Local; Animals; Behavior, Animal; Cocaine; Conditioning, Psychological; Hyperkinesis; Illicit Drugs; Injections, Intraperitoneal; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Morphine; Motor Activity; Species Specificity | 2005 |
Effects of atypical antipsychotic drugs on intralipid intake and cocaine-induced hyperactivity in rats.
Topics: Animals; Antipsychotic Agents; Cocaine; Dibenzothiazepines; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Eating; Fat Emulsions, Intravenous; Female; Hyperkinesis; Male; Motor Activity; Piperazines; Quetiapine Fumarate; Rats; Risperidone; Thiazoles | 2006 |
Addiction-related alterations in D1 and D2 dopamine receptor behavioral responses following chronic cocaine self-administration.
Topics: Animals; Behavior, Addictive; Brain; Chronic Disease; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Disease Models, Animal; Dopamine; Dopamine Agonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Hyperkinesis; Male; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Reward; Self Administration; Substance Withdrawal Syndrome | 2007 |
Augmented cocaine-induced accumbal dopamine efflux, motor activity and place preference in rats fed with a tryptophan-deficient diet.
Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine; Environment, Controlled; Exploratory Behavior; Extracellular Fluid; Food, Formulated; Hydroxyindoleacetic Acid; Hyperkinesis; Male; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Serotonin; Tryptophan | 2006 |
GABA(B) receptor-positive modulation decreases selective molecular and behavioral effects of cocaine.
Topics: Animals; Baclofen; Behavior, Addictive; Brain; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Cyclic AMP Response Element-Binding Protein; Cyclopentanes; Disease Models, Animal; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; GABA Agonists; Hyperkinesis; Male; Mice; Mice, Inbred C57BL; Proto-Oncogene Proteins c-fos; Pyrimidines; Receptors, GABA-B; Signal Transduction; Synaptic Transmission | 2007 |
Validation of a mechanical apparatus for the measurement of avian walking.
Topics: Animals; Behavior, Animal; Brain; Central Nervous System Stimulants; Cocaine; Columbidae; Dose-Response Relationship, Drug; Electronics; Gait; Housing, Animal; Humans; Hyperkinesis; Locomotion; Male; Neuropharmacology; Neurophysiology; Observer Variation; Predictive Value of Tests; Reproducibility of Results; Transducers, Pressure; Videotape Recording; Walking | 2006 |
Reduction of corticostriatal glutamatergic fibers in basic fibroblast growth factor deficient mice is associated with hyperactivity and enhanced dopaminergic transmission.
Topics: Actins; Analysis of Variance; Animals; Apomorphine; Cocaine; Dextroamphetamine; Dopamine; Dopamine Agents; Excitatory Amino Acid Transporter 3; Exploratory Behavior; Fibroblast Growth Factor 2; Frontal Lobe; Glutamic Acid; Hyperkinesis; Mice; Mice, Knockout; Motor Activity; Neostriatum; Nerve Fibers; Neural Pathways; Presynaptic Terminals; RNA, Messenger; Synaptic Transmission; Vesicular Glutamate Transport Protein 1 | 2007 |
Analogs of SR-141716A (Rimonabant) alter d-amphetamine-evoked [3H] dopamine overflow from preloaded striatal slices and amphetamine-induced hyperactivity.
Topics: Animals; Behavior, Animal; Cocaine; Corpus Striatum; Dextroamphetamine; Dopamine; Dopamine Uptake Inhibitors; Hyperkinesis; Male; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Rimonabant; Time Factors; Tritium | 2007 |
Systemic ghrelin sensitizes cocaine-induced hyperlocomotion in rats.
Topics: Animals; Cocaine; Drug Synergism; Ghrelin; Hyperkinesis; Male; Motor Activity; Rats; Rats, Sprague-Dawley | 2008 |
Anxiogenic effects of cocaine withdrawal in zebrafish.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Cocaine; Diazepam; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Hyperkinesis; Male; Motor Activity; Statistics, Nonparametric; Stereotyped Behavior; Substance Withdrawal Syndrome; Time Factors; Zebrafish | 2008 |
Aripiprazole, an atypical antipsychotic, prevents the motor hyperactivity induced by psychotomimetics and psychostimulants in mice.
Topics: Amphetamine; Animals; Antipsychotic Agents; Aripiprazole; Catalepsy; Central Nervous System Stimulants; Cocaine; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Partial Agonism; Excitatory Amino Acid Antagonists; Glutamine; Haloperidol; Hyperkinesis; Ketamine; Locomotion; Male; Mice; Motor Activity; Piperazines; Quinolones; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Time Factors | 2008 |
Reversal of cocaine-induced planarian behavior by parthenolide and related sesquiterpene lactones.
Topics: Algorithms; Animals; Behavior, Animal; Chromatography, High Pressure Liquid; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Hyperkinesis; Mass Spectrometry; Motor Activity; Planarians; Santonin; Sesquiterpenes; Sesquiterpenes, Eudesmane; Spectrometry, Mass, Electrospray Ionization | 2008 |
Alpha2-containing GABA(A) receptors are involved in mediating stimulant effects of cocaine.
Topics: Animals; Autoradiography; Azides; Benzodiazepines; Brain Chemistry; Central Nervous System Stimulants; Cocaine; Diazepam; Dose-Response Relationship, Drug; GABA Modulators; Hyperkinesis; Mice; Mice, Knockout; Midazolam; Motor Activity; Protein Subunits; Receptors, GABA-A | 2008 |
Enhancement of cocaine-induced hyperactivity in mice by benzodiazepines: evidence for an interaction of GABAergic processes with catecholaminergic neurons?
Topics: Animals; Benzodiazepines; Catecholamines; Cocaine; Drug Synergism; gamma-Aminobutyric Acid; Humans; Hyperkinesis; Male; Mice; Neurons; Synaptic Transmission | 1981 |
Classical conditioning, decay and extinction of cocaine-induced hyperactivity and stereotypy.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Brain Chemistry; Cocaine; Conditioning, Classical; Dopamine; Extinction, Psychological; Homovanillic Acid; Humans; Hyperkinesis; Male; Rats; Rats, Inbred Strains; Stereotyped Behavior; Time Factors | 1983 |
Elimination of cocaine-induced hyperactivity and dopamine-mediated neurophysiological effects in dopamine D1 receptor mutant mice.
Topics: Animals; Behavior, Animal; Cocaine; Dopamine; Electric Conductivity; Hyperkinesis; Male; Mice; Mice, Mutant Strains; Neurons; Nucleus Accumbens; Receptors, Dopamine D1; Receptors, Dopamine D2; Signal Transduction; Spiperone | 1994 |
Prevention of cocaine-induced hyperactivity by a naloxone isomer with no opiate antagonist activity.
Topics: Animals; Cocaine; Hyperkinesis; Male; Mice; Motor Activity; Naloxone; Narcotic Antagonists; Stereoisomerism | 1996 |
5-HT4 receptor antagonism does not affect motor and reward mechanisms in the rat.
Topics: Amphetamine; Animals; Behavior, Animal; Cocaine; Dioxanes; Hyperkinesis; Male; Motor Activity; Nicotine; Piperidines; Rats; Rats, Sprague-Dawley; Self Stimulation; Serotonin Antagonists | 1998 |
Effects of the 5-HT2C/2B antagonist SB 206553 on hyperactivity induced by cocaine.
Topics: Animals; Cocaine; Hyperkinesis; Indoles; Male; Motor Activity; Neurons; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin; Serotonin Antagonists | 1999 |
Strain and sex differences in the locomotor response and behavioral sensitization to cocaine in hyperactive rats.
Topics: Animals; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Female; Hyperkinesis; Male; Motor Activity; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sex Characteristics; Species Specificity | 1999 |
The effects of the 5-hydroxytryptamine(1A) agonist 8-hydroxy-2-(di-n-propylamino)tetralin on spontaneous activity, cocaine-induced hyperactivity and behavioral sensitization: a microanalysis of locomotor activity.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Cocaine; Dose-Response Relationship, Drug; Drug Interactions; Hyperkinesis; Locomotion; Male; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists; Time Factors | 2000 |
Involvement of the nucleus accumbens and medial prefrontal cortex in the expression of conditioned hyperactivity to a cocaine-associated environment in rats.
Topics: Amygdala; Animals; Baclofen; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Dose-Response Relationship, Drug; Hippocampus; Hyperkinesis; Male; Muscimol; Neural Inhibition; Neurons; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B | 2000 |
Short-term contextual sensitisation and conditioned hyperkinesia produced by cocaine in suckling rats aged 4-10 days and 14-20 days.
Topics: Animals; Animals, Newborn; Animals, Suckling; Behavior, Animal; Cocaine; Conditioning, Psychological; Dopamine Uptake Inhibitors; Female; Hyperkinesis; Male; Pregnancy; Rats; Rats, Sprague-Dawley | 2001 |
L-tryptophan attenuation of the dopaminergic and behavioral responses to cocaine.
Topics: Animals; Behavior, Animal; Cocaine; Dopamine; Hyperkinesis; Injections, Intraperitoneal; Injections, Intravenous; Male; Microdialysis; Narcotic Antagonists; Nucleus Accumbens; Random Allocation; Rats; Rats, Sprague-Dawley; Tryptophan | 2001 |
Critical role of alpha1-adrenergic receptors in acute and sensitized locomotor effects of D-amphetamine, cocaine, and GBR 12783: influence of preexposure conditions and pharmacological characteristics.
Topics: Adrenergic alpha-Antagonists; Amphetamine; Animals; Brain; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Drug Tolerance; Habituation, Psychophysiologic; Hyperkinesis; Male; Neurons; Norepinephrine; Piperazines; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Sodium Chloride; Synaptic Transmission | 2002 |
Protective effects of cannabinoid receptor ligands analogous to anandamide against cocaine toxicity.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cocaine; Cyclohexanols; Drug Interactions; Drug Therapy, Combination; Endocannabinoids; Hyperkinesis; Ligands; Mice; Mice, Inbred ICR; Polyunsaturated Alkamides; Receptors, Cannabinoid; Receptors, Drug; Seizures | 2001 |
Serotonin 5-HT(2C) receptors in nucleus accumbens regulate expression of the hyperlocomotive and discriminative stimulus effects of cocaine.
Topics: Animals; Cocaine; Discrimination, Psychological; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Ethylamines; Hyperkinesis; Indoles; Male; Microinjections; Motor Activity; Nucleus Accumbens; Pyrazines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiro Compounds; Sulfonamides | 2002 |
Role of the dopamine D3 receptor in reactivity to cocaine-associated cues in mice.
Topics: Animals; Brain; Brain-Derived Neurotrophic Factor; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Cues; Dopamine Agonists; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Gene Expression; Genotype; Hyperkinesis; Male; Mice; Mice, Knockout; Piperazines; Proto-Oncogene Proteins c-fos; Receptors, Dopamine D2; Receptors, Dopamine D3; Reinforcement, Psychology; RNA, Messenger; Up-Regulation | 2002 |
Noradrenergic mechanisms appear not to be involved in cocaine-induced seizures and lethality.
Topics: Adrenergic alpha-Antagonists; Animals; Cocaine; Desipramine; Dioxanes; Hyperkinesis; Idazoxan; Injections, Intraperitoneal; Mice; Norepinephrine; Seizures | 1990 |
Effects of prenatal exposure to cocaine or related drugs on rat developmental and neurological indices.
Topics: Amitriptyline; Animals; Cocaine; Female; Hyperkinesis; Male; Nervous System; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Substance-Related Disorders | 1990 |
Carbamazepine retards the development of cocaine-kindled seizures but not sensitization to cocaine-induced hyperactivity.
Topics: Animals; Carbamazepine; Cocaine; Hyperkinesis; Kindling, Neurologic; Male; Motor Activity; Probability; Rats; Rats, Inbred Strains; Seizures; Stereotyped Behavior | 1990 |
Microinjection of a glutamate antagonist into the nucleus accumbens reduces psychostimulant locomotion in rats.
Topics: Amphetamine; Analysis of Variance; Animals; Caffeine; Cocaine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamates; Hyperkinesis; Male; Microinjections; Motor Activity; Nucleus Accumbens; Rats; Rats, Inbred Strains; Septal Nuclei | 1989 |
Unexpected cocaine intoxication in a fourteen month old child following topical administration.
Topics: Administration, Topical; Bronchoscopy; Cocaine; Humans; Hyperkinesis; Infant; Male; Meperidine | 1987 |
Paradoxical amphetamine effect in hyperactive rats in relation to norepinephrine metabolism.
Topics: Amino Acids; Amphetamine; Animals; Brain; Chlorine; Cocaine; Desipramine; Humans; Hyperkinesis; Iproniazid; Male; Monoamine Oxidase; Motor Activity; Norepinephrine; Normetanephrine; Phenylalanine; Pyrogallol; Quinolizines; Rats; Serotonin; Tritium | 1970 |