cocaine and Encephalopathy, Toxic

cocaine has been researched along with Encephalopathy, Toxic in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (2.94)18.2507
2000's15 (44.12)29.6817
2010's16 (47.06)24.3611
2020's2 (5.88)2.80

Authors

AuthorsStudies
Li, X; Nie, J; Niu, Q; Zhang, H1
da Silva, MAA; Dal'Jovem, LF; de Oliveira Duro, S; de Souza Prates, S; Faião-Flores, F; Garcia, RCT; Marcourakis, T; Maria-Engler, SS; Udo, MSB1
Arbo, MD; Barros, EJ; Cestonaro, LV; Costa-Valle, MT; Dallegrave, E; Dos Santos, NG; Garcia, SC; Izolan, L; Laurentino, AOM; Leal, MB; Marques, D; Piton, YV; Schaefer, PG; Sebben, V; Solómon, J; Tonietto, BD1
Almeida, FB; Barros, HMT; Freese, L; Gomez, R; Hansen, AW; Heidrich, N; Moura, DJ; Steffens, L; Steinmetz, A1
Lopez-Rodriguez, AB; Viveros, MP1
Colado, MI; Granado, N; Gutiérrez-López, MD; Moratalla, R; O'Shea, E; Peraile, I; Torres, E1
Gramage, E; Herradón, G; Pérez-García, C; Vicente-Rodríguez, M1
Andrade, PB; Pereira, RB; Valentão, P1
Abdalla, FM; Afeche, SC; Camarini, R; Conn, PJ; da Costa, JL; da Silva, MA; Dati, LM; Garcia, RC; Gorjão, R; Marcourakis, T; Niswender, CM; Sandoval, MR; Torres, LH; Udo, MS; Yonamine, M1
Cartier R, L; González L, D; Harán D, J1
Mhillaj, E; Neri, M; Pomara, C; Schiavone, S; Trabace, L; Turillazzi, E1
Riezzo, I; Schiavone, S; Trabace, L; Turillazzi, E1
Bordia, T; Huang, LZ; Michael McIntosh, J; Parameswaran, N; Quik, M1
Muresanu, D; Patnaik, R; Sharma, A; Sharma, HS1
Colado, MI; Izco, M; Lopez-Jimenez, A; Lopez-Moreno, JA; Mayado, A; O'Shea, E; Peraile, I; Torres, E1
Borges, F; Cunha-Oliveira, T; Garrido, J; Macedo, T; Oliveira, CR; Rego, AC1
Abad, S; Camarasa, J; Escubedo, E; Pubill, D; Torres, I1
Albein-Urios, N; Clark, L; Lozano, O; Martinez-González, JM; Verdejo-García, A1
Anderson, KL; Itzhak, Y; Liddie, S; Paz, A1
Jia, FL; Liu, X; Ruan, M; Wu, XY; Xue, R; Zhang, BX1
Booij, J; De Bruin, K; Den Heeten, GJ; Habraken, JB; Hatzidimitriou, G; Reneman, L; Ricaurte, GA1
Clarke, PB; Grant, RJ1
Achat, CN; Ali, SF; Anderson, KL; Itzhak, Y1
Achat-Mendes, CN; Ali, SF; Anderson, KL; Itzhak, Y1
Farrell, MA; Hutchinson, M; Molloy, FM; Ryan, A1
Achat-Mendes, C; Anderson, KL; Itzhak, Y1
Camarasa, J; Chipana, C; Escubedo, E; Pubill, D1
Arlien-Soeborg, P; Danielsen, ER; Kondziella, D1
Cho, AK; Fairbanks, LA; Jorgensen, MJ; Laćan, G; Melega, WP; Morton, G; Pham, J; Way, BM1
Booze, RM; Ferris, MJ; Mactutus, CF1
Cunha-Oliveira, T; Oliveira, CR; Rego, AC1
Fehlings, T; Kastrup, O; Leonhardt, G; Maschke, M; Wilhelm, HW1
Booij, J; de Wolff, FA; den Heeten, GJ; Lavalaye, J; Reneman, L; Schmand, B; van den Brink, W1
McCann, UD; Molliver, ME; Ricaurte, GA1

Reviews

6 review(s) available for cocaine and Encephalopathy, Toxic

ArticleYear
Bath salts and polyconsumption: in search of drug-drug interactions.
    Psychopharmacology, 2019, Volume: 236, Issue:3

    Topics: Alkaloids; Animals; Cannabinoids; Central Nervous System Stimulants; Cocaine; Drug Interactions; Humans; Illicit Drugs; Methamphetamine; Mice; Neurotoxicity Syndromes; Polypharmacy; Rats; Substance-Related Disorders

2019
A Comprehensive View of the Neurotoxicity Mechanisms of Cocaine and Ethanol.
    Neurotoxicity research, 2015, Volume: 28, Issue:3

    Topics: Animals; Brain; Central Nervous System Agents; Cocaine; Ethanol; Humans; Neurotoxicity Syndromes; Substance-Related Disorders

2015
The role of the NADPH oxidase derived brain oxidative stress in the cocaine-related death associated with excited delirium: A literature review.
    Toxicology letters, 2016, Sep-06, Volume: 258

    Topics: Animals; Brain; Cocaine; Delirium; Dopamine Uptake Inhibitors; Humans; Models, Neurological; NADPH Oxidases; Nerve Tissue Proteins; Neurons; Neurotoxicity Syndromes; Oxidative Stress; Psychotropic Drugs; Reactive Oxygen Species

2016
Cocaine-induced breakdown of the blood-brain barrier and neurotoxicity.
    International review of neurobiology, 2009, Volume: 88

    Topics: Animals; Blood-Brain Barrier; Brain; Brain Edema; Cerebrovascular Circulation; Cocaine; Dopamine Uptake Inhibitors; Fever; Humans; Neurotoxicity Syndromes

2009
Neurotoxic profiles of HIV, psychostimulant drugs of abuse, and their concerted effect on the brain: current status of dopamine system vulnerability in NeuroAIDS.
    Neuroscience and biobehavioral reviews, 2008, Volume: 32, Issue:5

    Topics: Animals; Brain; Cocaine; Dopamine; HIV; HIV Infections; Humans; Methamphetamine; Nervous System Diseases; Neural Pathways; Neurotoxicity Syndromes; Neurotoxins; Substance-Related Disorders

2008
Cellular and molecular mechanisms involved in the neurotoxicity of opioid and psychostimulant drugs.
    Brain research reviews, 2008, Volume: 58, Issue:1

    Topics: Amphetamine; Analgesics, Opioid; Animals; Brain; Central Nervous System Stimulants; Cocaine; Humans; Models, Biological; Neurotoxicity Syndromes; Substance-Related Disorders

2008

Other Studies

28 other study(ies) available for cocaine and Encephalopathy, Toxic

ArticleYear
Association of aryl hydrocarbon receptor gene polymorphism with the neurobehavioral function and autonomic nervous system function changes induced by benzo[a]pyrene exposure in coke oven workers.
    Journal of occupational and environmental medicine, 2013, Volume: 55, Issue:3

    Topics: Adult; Air Pollutants, Occupational; Autonomic Nervous System Diseases; Basic Helix-Loop-Helix Transcription Factors; Benzo(a)pyrene; Biomarkers; Case-Control Studies; China; Coke; Extraction and Processing Industry; Genetic Markers; Genotyping Techniques; Humans; Male; Middle Aged; Nervous System Diseases; Neuropsychological Tests; Neurotoxicity Syndromes; Occupational Diseases; Occupational Exposure; Polymorphism, Single Nucleotide; Pyrenes; Receptors, Aryl Hydrocarbon; Surveys and Questionnaires

2013
Anhydroecgonine methyl ester, a cocaine pyrolysis product, contributes to cocaine-induced rat primary hippocampal neuronal death in a synergistic and time-dependent manner.
    Archives of toxicology, 2021, Volume: 95, Issue:5

    Topics: Animals; Cocaine; Gas Chromatography-Mass Spectrometry; Hippocampus; Neurons; Neurotoxicity Syndromes; Pyrolysis; Rats

2021
Levamisole, a cocaine cutting agent, induces acute and subchronic systemic alterations in Wistar rats.
    Toxicology and applied pharmacology, 2021, 09-01, Volume: 426

    Topics: Animals; Antinematodal Agents; Behavior, Animal; Cocaine; Leukocyte Count; Levamisole; Liver; Male; Neurotoxicity Syndromes; Organ Size; Oxidative Stress; Rats, Wistar; Toxicity Tests, Acute

2021
Environmental enrichment reduces cocaine neurotoxicity during cocaine-conditioned place preference in male rats.
    Pharmacology, biochemistry, and behavior, 2018, Volume: 169

    Topics: Animals; Antioxidants; Brain; Catalase; Cocaine; Comet Assay; Conditioning, Classical; DNA Damage; Environment; Male; Neurotoxicity Syndromes; Oxidation-Reduction; Oxidative Stress; Rats, Wistar; Reactive Oxygen Species; Reward; Superoxide Dismutase

2018
Cocaine potentiates MDMA-induced oxidative stress but not dopaminergic neurotoxicity in mice: implications for the pathogenesis of free radical-induced neurodegenerative disorders.
    Psychopharmacology, 2013, Volume: 230, Issue:1

    Topics: Animals; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Free Radicals; Glutathione Peroxidase; Lipid Peroxidation; Male; Mice; Microdialysis; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxicity Syndromes; Oxidative Stress; Time Factors

2013
Phosphoproteomic analysis of the striatum from pleiotrophin knockout and midkine knockout mice treated with cocaine reveals regulation of oxidative stress-related proteins potentially underlying cocaine-induced neurotoxicity and neurodegeneration.
    Toxicology, 2013, Dec-06, Volume: 314, Issue:1

    Topics: Animals; Blotting, Western; Carrier Proteins; Chromatography, Affinity; Cocaine; Cytokines; Electrophoresis, Polyacrylamide Gel; Mice; Mice, Knockout; Midkine; Neostriatum; Neurodegenerative Diseases; Neurotoxicity Syndromes; Oxidative Stress; Phosphoproteins; Phosphorylation; Proteomics; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tyrosine

2013
M1 and M3 muscarinic receptors may play a role in the neurotoxicity of anhydroecgonine methyl ester, a cocaine pyrolysis product.
    Scientific reports, 2015, Dec-02, Volume: 5

    Topics: Animals; Apoptosis; CHO Cells; Cocaine; Cricetinae; Cricetulus; DNA Fragmentation; Female; Hippocampus; Neurotoxicity Syndromes; Neurotoxins; Rats; Receptor, Muscarinic M1; Receptor, Muscarinic M3; Time Factors

2015
[Fatal toxic leukoencephalopathy associated with consumption of pasta base of cocaine: Report of three cases].
    Revista medica de Chile, 2015, Volume: 143, Issue:11

    Topics: Adult; Cocaine; Consciousness Disorders; Fatal Outcome; Female; Headache; Humans; Leukoencephalopathies; Magnetic Resonance Imaging; Male; Neurotoxicity Syndromes; Young Adult

2015
Involvement of the NADPH Oxidase NOX2-Derived Brain Oxidative Stress in an Unusual Fatal Case of Cocaine-Related Neurotoxicity Associated With Excited Delirium Syndrome.
    Journal of clinical psychopharmacology, 2016, Volume: 36, Issue:5

    Topics: Adult; Cocaine; Delirium; Fatal Outcome; Humans; Male; Membrane Glycoproteins; NADPH Oxidase 2; NADPH Oxidases; Neurotoxicity Syndromes; Oxidative Stress

2016
Nicotine is neuroprotective when administered before but not after nigrostriatal damage in rats and monkeys.
    Journal of neurochemistry, 2009, Volume: 109, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amphetamine; Analysis of Variance; Animals; Autoradiography; Cocaine; Conotoxins; Corpus Striatum; Cotinine; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Iodine Isotopes; Male; Motor Activity; Neuroprotective Agents; Neurotoxicity Syndromes; Nicotine; Oxidopamine; Protein Binding; Rats; Rats, Sprague-Dawley; Saimiri; Substantia Nigra; Time Factors

2009
Dopamine transporter down-regulation following repeated cocaine: implications for 3,4-methylenedioxymethamphetamine-induced acute effects and long-term neurotoxicity in mice.
    British journal of pharmacology, 2010, Volume: 159, Issue:1

    Topics: Animals; Cell Membrane; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Down-Regulation; Male; Mice; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxicity Syndromes; Piperidines; Protein Kinase C; Protein Kinase Inhibitors; Reward; Time Factors

2010
Neurotoxicity of heroin-cocaine combinations in rat cortical neurons.
    Toxicology, 2010, Sep-30, Volume: 276, Issue:1

    Topics: Adenosine Triphosphate; Animals; Apoptosis; Caspase 3; Cell Survival; Cerebral Cortex; Cocaine; Cytochromes c; Drug Interactions; Heroin; Membrane Potential, Mitochondrial; Necrosis; Neurons; Neurotoxicity Syndromes; Rats

2010
Comparative neurochemical profile of 3,4-methylenedioxymethamphetamine and its metabolite alpha-methyldopamine on key targets of MDMA neurotoxicity.
    Neurochemistry international, 2011, Volume: 58, Issue:1

    Topics: Animals; Cell Membrane; Cell Survival; Cocaine; Deoxyepinephrine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; In Vitro Techniques; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxicity Syndromes; Paroxetine; PC12 Cells; Protein Conformation; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Synaptosomes

2011
Comparison of impulsivity and working memory in cocaine addiction and pathological gambling: Implications for cocaine-induced neurotoxicity.
    Drug and alcohol dependence, 2012, Nov-01, Volume: 126, Issue:1-2

    Topics: Adult; Analysis of Variance; Area Under Curve; Cocaine; Cocaine-Related Disorders; Executive Function; Female; Gambling; Humans; Impulsive Behavior; Male; Memory, Short-Term; Neuropsychological Tests; Neurotoxicity Syndromes; Stroop Test; Surveys and Questionnaires

2012
The effect of phosphodiesterase inhibitors on the extinction of cocaine-induced conditioned place preference in mice.
    Journal of psychopharmacology (Oxford, England), 2012, Volume: 26, Issue:10

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Amygdala; Animals; Association Learning; Behavior, Animal; Cocaine; Cyclic GMP; Dose-Response Relationship, Drug; Extinction, Psychological; Hippocampus; Learning Disabilities; Male; Memory, Long-Term; Mice; Mice, 129 Strain; Molecular Targeted Therapy; Nerve Tissue Proteins; Neurons; Neurotoxicity Syndromes; Phosphodiesterase Inhibitors; Pyrazoles; Pyrimidines; Spatial Behavior

2012
[Protective effect of 2,4-dihydroxybenzophenone on cocaine-induced hepatotoxicity and neurotoxicity in mice].
    Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2012, Jun-18, Volume: 44, Issue:3

    Topics: Animals; Antioxidants; Benzophenones; Chemical and Drug Induced Liver Injury; Cocaine; Male; Mice; Mice, Inbred ICR; Neurotoxicity Syndromes

2012
Validity of [123I]beta-CIT SPECT in detecting MDMA-induced serotonergic neurotoxicity.
    Synapse (New York, N.Y.), 2002, Dec-01, Volume: 46, Issue:3

    Topics: Animals; Autoradiography; Brain; Brain Mapping; Cocaine; Drug Administration Schedule; Iodine Radioisotopes; Macaca mulatta; Magnetic Resonance Imaging; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxicity Syndromes; Protein Binding; Rats; Serotonin Agents; Time Factors; Tomography, Emission-Computed, Single-Photon

2002
Susceptibility of ascending dopamine projections to 6-hydroxydopamine in rats: effect of hypothermia.
    Neuroscience, 2002, Volume: 115, Issue:4

    Topics: Animals; Body Temperature; Cell Survival; Cocaine; Disease Susceptibility; Dopamine; Efferent Pathways; Hypothermia, Induced; Male; Medial Forebrain Bundle; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Oxidopamine; Pentobarbital; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Substantia Nigra; Tyrosine 3-Monooxygenase; Ventral Tegmental Area

2002
Relevance of MDMA ("ecstasy")-induced neurotoxicity to long-lasting psychomotor stimulation in mice.
    Psychopharmacology, 2003, Volume: 166, Issue:3

    Topics: Animals; Brain Chemistry; Carrier Proteins; Central Nervous System Stimulants; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Hallucinogens; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Tissue Proteins; Neurotoxicity Syndromes; Receptors, Serotonin; Serotonin; Serotonin Plasma Membrane Transport Proteins; Time Factors

2003
Long-lasting behavioral sensitization to psychostimulants following p-chloroamphetamine-induced neurotoxicity in mice.
    Neuropharmacology, 2004, Volume: 46, Issue:1

    Topics: Anesthetics, Local; Animals; Behavior, Animal; Binding Sites; Brain Chemistry; Carrier Proteins; Chromatography, High Pressure Liquid; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Drug Administration Schedule; Drug Interactions; Hallucinogens; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Tissue Proteins; Neurotoxicity Syndromes; p-Chloroamphetamine; Serotonin; Serotonin Agents; Serotonin Plasma Membrane Transport Proteins; Time Factors

2004
Fatal toxic leukoencephalopathy: clinical, radiological, and necropsy findings in two patients.
    Journal of neurology, neurosurgery, and psychiatry, 2005, Volume: 76, Issue:7

    Topics: Adult; Brain; Brain Stem; Cerebellum; Cerebral Cortex; Cocaine; Cocaine-Related Disorders; Disease Progression; Dominance, Cerebral; Fatal Outcome; Heroin; Heroin Dependence; Humans; Male; Middle Aged; Nerve Degeneration; Nerve Fibers; Neurologic Examination; Neurotoxicity Syndromes

2005
Impairment in consolidation of learned place preference following dopaminergic neurotoxicity in mice is ameliorated by N-acetylcysteine but not D1 and D2 dopamine receptor agonists.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2007, Volume: 32, Issue:3

    Topics: Acetylcysteine; Animals; Behavior, Animal; Brain Chemistry; Cocaine; Conditioning, Operant; Disease Models, Animal; Dopamine; Dopamine Agents; Dopamine Agonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Free Radical Scavengers; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Glutathione; Learning Disabilities; Male; Methamphetamine; Mice; Neurotoxicity Syndromes; Tyrosine 3-Monooxygenase

2007
Protection against MDMA-induced dopaminergic neurotoxicity in mice by methyllycaconitine: involvement of nicotinic receptors.
    Neuropharmacology, 2006, Volume: 51, Issue:4

    Topics: Aconitine; Analysis of Variance; Animals; Cocaine; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Flow Cytometry; Male; Mice; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Neuroprotective Agents; Neurotoxicity Syndromes; Nicotinic Agonists; Nicotinic Antagonists; Radioligand Assay; Reactive Oxygen Species; Receptors, Nicotinic; Synaptosomes; Tritium

2006
Fatal encephalopathy after an isolated overdose of cocaine.
    Journal of neurology, neurosurgery, and psychiatry, 2007, Volume: 78, Issue:4

    Topics: Adult; Brain; Cocaine; Electroencephalography; Fatal Outcome; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neurotoxicity Syndromes; Vasoconstrictor Agents

2007
Long-term methamphetamine administration in the vervet monkey models aspects of a human exposure: brain neurotoxicity and behavioral profiles.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008, Volume: 33, Issue:6

    Topics: Analysis of Variance; Animals; Autoradiography; Behavior, Animal; Benzazepines; Brain; Brain Chemistry; Central Nervous System Stimulants; Chlorocebus aethiops; Cocaine; Disease Models, Animal; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Methamphetamine; Neurotoxicity Syndromes; Protein Binding; Raclopride; Social Behavior; Tritium

2008
Toxic leukoencephalopathy after intravenous consumption of heroin and cocaine with unexpected clinical recovery.
    Journal of neurology, 1999, Volume: 246, Issue:9

    Topics: Adult; Brain; Cocaine; Dopamine Uptake Inhibitors; Heroin; Humans; Magnetic Resonance Imaging; Male; Narcotics; Neurotoxicity Syndromes; Substance Abuse, Intravenous

1999
Cortical serotonin transporter density and verbal memory in individuals who stopped using 3,4-methylenedioxymethamphetamine (MDMA or "ecstasy"): preliminary findings.
    Archives of general psychiatry, 2001, Volume: 58, Issue:10

    Topics: Adult; Brain Chemistry; Carrier Proteins; Cerebral Cortex; Cocaine; Female; Follow-Up Studies; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Memory Disorders; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Tissue Proteins; Neuropsychological Tests; Neurotoxicity Syndromes; Prognosis; Serotonin Plasma Membrane Transport Proteins; Substance-Related Disorders; Time Factors; Tomography, Emission-Computed, Single-Photon; Verbal Learning

2001
"Ecstasy" and serotonin neurotoxicity: new findings raise more questions.
    Archives of general psychiatry, 2001, Volume: 58, Issue:10

    Topics: Brain Chemistry; Carrier Proteins; Cerebral Cortex; Cocaine; Follow-Up Studies; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Memory Disorders; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Tissue Proteins; Neurotoxicity Syndromes; Prognosis; Serotonin Plasma Membrane Transport Proteins; Substance-Related Disorders; Tomography, Emission-Computed, Single-Photon

2001