Compounds > cocaine

cocaine and Disease Models, Animal

cocaine has been researched along with Disease Models, Animal in 760 studies

Research

Studies (760)

TimeframeStudies, this research(%)All Research%
pre-199017 (2.24)18.7374
1990's68 (8.95)18.2507
2000's271 (35.66)29.6817
2010's356 (46.84)24.3611
2020's48 (6.32)2.80

Authors

AuthorsStudies
Slowik, T1
Ociepiński, M; Szaflarska-Stojko, E; Zyłka-Włoszczyk, M1
Cakir, AE; Chow, EC; Essoh, A; Foster, DM; Guo, Y; Huebschman, JL; Monterrey, CA; Omoregie, CC; Sevilla-Gutierrez, A; Smith, LN1
Ambrosio, E; Capellán, R; Casquero-Veiga, M; Desco, M; Higuera-Matas, A; Ibáñez-Moragues, M; Magro-Calvo, N; Marcos, A; Morcillo, MÁ; Moreno-Fernández, M; Orihuel, J; Oteo-Vives, M; Soto-Montenegro, ML; Ucha, M1
Cortez, I; Cunningham, KA; Dineley, KT; Dunn, TJ; Fox, RG; Gao, J; Hommel, JD; Kaphalia, BS; Kuo, YF; McGrath, EL; Schlagal, CR; Stutz, SJ; Wu, P1
Nawarawong, NN; Olsen, CM1
Dietz, DM; Gancarz, AM; Gobira, PH; Lepack, AE; Martin, JA; Maze, I; Mitra, S; Neve, RL; Ramakrishnan, A; Shen, L; Stewart, AF; Wang, ZJ; Werner, CT1
Beauvais, G; Ehrlich, ME; Gonzalez-Alegre, P; Koch, RJ; Martin, J; Patel, JC; Rice, ME; Walker, RH1
Andrews, AM; Cannella, LA; Corbett, CB; Kahn, J; McGary, H; Ramirez, SH; Razmpour, R1
Lane, AE; Lane, DA; Qian, L; Trubetckaia, O; Zhou, P1
Cano, M; Gad, M; Green, KN; Leslie, FM; Linker, KE; Tawadrous, P; Wood, MA1
Jimenez-Rivera, CA; Santos-Vera, B; Vazquez-Torres, R; Velasquez-Martinez, MC; Velez-Hernandez, ME1
Blanco-Gandía, MDC; Miñarro López, J; Ródenas-González, F; Rodriguez-Arias, M1
Ambrosio, E; Anadón, A; Capellán, R; Crego, AL; Higuera-Matas, A; Marcos, A; Martínez-Larrañaga, MR; Moreno, M; Mª de Paz, A; Orihuel, J; Ucha, M1
Allain, F; Samaha, AN2
Ambrosio, E; Borcel, É; Higuera-Matas, A; Santos-Toscano, R; Ucha, M1
Borroto-Escuela, DO; Filip, M; Frankowska, M; Fuxe, K; Gawlińska, K; Gawliński, D; Wydra, K1
Frankowska, M; Gamberini, S; Gawlińska, K; Gawliński, D; Jastrzębska, J; Pieniążek, R; Suder, A; Wydra, K1
Gauthier, JM; Kantak, KM; Knyazhanskaya, E; Man, HY; Mathieson, E; Rodriguez-Echemendia, P1
Bariselli, S; Creed, MC; Kravitz, AV; Miyazaki, NL1
Makiguchi, A; Okada, T; Shioda, K; Suda, S1
Camarasa, J; Cantacorps, L; Duart-Castells, L; Escubedo, E; López-Arnau, R; Mera, P; Montagud-Romero, S; Pubill, D; Puster, B; Serra, D; Valverde, O1
Calleti, G; Flores Peres, V; Fraga de Souza, M; Freese, L; Gomez, R; Maria Tannhauser Barros, H; Schüler Nin, M1
Filip, M; Frankowska, M; Gawlińska, K; Gawliński, D; Korostyński, M; Piechota, M1
Acher, F; Befort, K; Bourdy, R; De Sa Nogueira, D; Filliol, D; McCort-Tranchepain, I; Quessada, C; Romieu, P; Zwiller, J1
Andrade, YCP; Batista, LA; Del Bel, EA; Fanelli, C; Issy, AC; Liégeois, JF; Minaldi, E; Moreira, FA; Rodrigues, LCM; Ropke, J; Viana, TG1
Chai, YG; Choi, MR; Im, CN; Jin, YB; Kim, DJ; Kim, HN; Lee, SR1
Ahdoot, HL; Bareli, T; Barnea, R; Ben-Moshe, H; Maayan, R; Roska, P; Warhaftig, G; Weizman, A; Yadid, G1
Antonelli, MC; Castillo Díaz, F; Dalto, JF; Medina, JH; Pastor, V; Sanabria, VC1
Kang, UG; Koo, JW; Xu, S1
Jayanthi, LD; Ragu Varman, D; Ramamoorthy, S; Subler, MA; Windle, JJ1
Cirino, TJ; McLaughlin, JP1
Bertrand, SJ; Booze, RM; Harrod, SB; Illenberger, JM; Mactutus, CF; McLaurin, KA1
Bryant, CD; Kantak, KM; Mathieson, E; Stots, C1
Avalos, MP; Bollati, FA; Cancela, LM; De Giovanni, LN; Euliarte, PV; Guzman, AS; Mongi-Bragato, B; Rigoni, D; Sanchez, MA; Virgolini, MB1
Arenas, MC; Manzanedo, C; Pujante-Gil, S1
Arenas, MC; Blanco-Gandía, MC; Castro-Zavala, A; Manzanedo, C; Martín-Sánchez, A; Miñarro, J; Valverde, O1
Banks, ML; Negus, SS2
Belujon, P; Chalon, S; Galineau, L; Lepelletier, FX; Nicolas, C; Solinas, M; Tauber, C1
Hou, W; Le, Q; Li, Y; Ma, D; Ma, L; Song, H; Wu, F; Yan, B; Yu, X; Zhou, Y; Zhu, H1
Briand, LA; Ellis, AS; Fosnocht, AQ; Lucerne, KE1
Accoto, A; Andolina, D; Coassin, A; D'Amato, FR; Di Segni, M; Lizzi, AR; Luchetti, A; Luzi, C; Pascucci, T; Ventura, R1
Lisieski, MJ; Perrine, SA1
Filip, M; Frankowska, M; Jastrzębska, J; Nowak, E; Przegaliński, E; Suder, A; Wydra, K1
Lattal, KM; Navis, TM; Pizzimenti, CL1
Brien-Ladner, AO; Dalvi, P; Dhillon, NK; Konstantinova, T; Sanderson, M; Sharma, H1
Beiser, T; Kohen, R; Numa, R; Yaka, R1
Badve, PS; Barson, JR; Bass, CE; Bernstein, DL; España, RA1
Berini, CR; Freeman, LR; Ghee, SM; Leong, KC; Reichel, CM; See, RE1
Aguilar, MA; Blanco-Gandía, MC; Miñarro, J; Montagud-Romero, S; Rodríguez-Arias, M1
Andersen, EH; Johns, JM; Mace, KD; Martin, WK; Robinson, DL; Shnitko, TA; Sullivan, KM; Williams Avram, SK1
Allain, F; Bouayad-Gervais, K; Samaha, AN1
Hales, CA; Houghton, CJ; Robinson, ESJ1
Pagán, OR1
Hutchinson, CV; Mohammed Jawad, RA; Prados, J1
Browning, KO; Craig, AR; Nall, RW; Shahan, TA1
Aungier, J; Cuesta, M; Morton, AJ; Ouk, K1
Farrell, MR; Mahler, SV; Schoch, H1
Dell'Acqua, ML; Guercio, LA; Hofmann, ME; Pierce, RC; Schmidt, HD; Sigman, JS; Swinford-Jackson, SE; Wimmer, ME1
Cotto, B; Ferrero, K; Langford, D; Natarajaseenivasan, K; Sayre, M; Wesley, L1
Belin, D; Everitt, BJ; Giuliano, C1
Contet, C; Geenen, B; George, O; Homberg, JR; Karel, P; Koob, GF; Kozicz, T; Latour, J; Meyer, F; van der Doelen, RHA; van Hulten, JA; Verheij, MMM1
Bao, MM; Dong, C; Dykxhoorn, DM; Pierce, CT; Sartor, GC; Wahlestedt, CR; Wang, H; Wei, J; Zhu, W1
Knackstedt, L; Leong, KC; Logan, CN; Peris, J; Reichel, CM; Weber, RA1
Belozertseva, I; Bespalov, AY; Dravolina, OA; Spanagel, R; Takahashi, TT; Vengeliene, V; Zvartau, E1
Ball, KT; Best, O; Collins, T; Edson, H; Hagan, E; Nardini, S; Neuciler, P; Smolinsky, M; Stone, E; Tosh, L; Woodlen, K1
Buzsáki, G; Cassataro, D; Cumpelik, A; Peyrache, A; Sjulson, L1
Bertrand, SJ; Booze, RM; Harrod, SB; Mactutus, CF; Moran, LM1
Collins, GT; France, CP1
Bergman, J; de Moura, FB; Kohut, SJ1
Budde, MD; Gerndt, CH; Muelbl, MJ; Nawarawong, NN; Olsen, CM; Shah, AS; Slaker, ML; Stemper, BD1
Du, Q; Sapozhnikov, DM; Teng, H; Wang, Y; Zhao, M1
Kalisch, B; Leri, F; Thériault, RK1
Alessi, L; Robison, LS; Thanos, PK1
Ferland, JN; Kaur, S; Riparip, LK; Rosi, S; Vonder Haar, C; Winstanley, CA1
Bellone, C; Bimpisidis, Z; Creed, M; Dorst, MC; Dumas, S; Lüscher, C; Papathanou, M; Pettersson, H; Silberberg, G; Wallén-Mackenzie, Å1
Hadad, NA; Hiller, H; Knackstedt, LA; Krause, EG; Namba, MD; Schwendt, M; Shallcross, J; Wu, L1
Bossert, JM; Caprioli, D; Hope, BT; Li, X; Quintana-Feliciano, R; Rubio, FJ; Selvam, PV; Shaham, Y; Valle, FSD; Venniro, M; Warren, BL; Witonsky, KFR1
Bifone, A; Cannella, N; Ciccocioppo, R; Cippitelli, A; Domi, E; Gozzi, A; Li, H; Matzeu, A; Scuppa, G; Ubaldi, M; Weiss, F1
Amini, S; Burdo, TH; Datta, PK; Gordon, J; Khalili, K; Langford, TD; Mohseni Ahooyi, T; Shekarabi, M; Torkzaban, B1
Cosme, CV; Gutman, AL; LaLumiere, RT; Noterman, MF; Wemmie, JA; Worth, WR1
Allain, F; Gueye, AB; Samaha, AN1
Gardner, EL; Wang, B; Wise, RA; You, ZB1
Ballestín, R; Castro-Zavala, A; Ferrer-Pérez, C; Filarowska, J; Luján, MÁ; Miñarro, J; Rodríguez-Arias, M; Valverde, O1
Ary, AW; Ben-Shahar, O; Courson, J; Hiller, JW; Kippin, TE; Miller, BW; Ruppert-Majer, M; Shahin, JR; Shin, CB; Szumlinski, KK; Wroten, MG1
Amlal, H; Amlal, S; Marckel, JA; Norman, AB; Wetzel, HN1
Blakely, RD; Carroll, FI; Davis, GL; Gowrishankar, R; Gresch, PJ; Hahn, MK; Katamish, RM; Peart, R; Rabil, MJ; Stewart, A1
Baunez, C; Giorla, E; Montanari, C; Pelloux, Y2
Ambrosio, E; Ballesteros-Yáñez, I; Castillo, CA; Higuera-Matas, A; Marcos, A; Orihuel, J; Roura-Martínez, D; Ucha, M1
Calipari, ES; Johnson, AR; Kutlu, MG; Lopez, AJ; Peck, EG; Sanders, CM; Sands, LP; Thibeault, KC1
Anier, K; Herodes, K; Kalda, A; Kipper, K; Matsalu, T; Niinep, K; Timmusk, T; Urb, M; Zharkovsky, A1
Deyama, S; Domoto, M; Hinoi, E; Kamii, H; Kaneda, K; Kaneko, S; Maejima, T; Mieda, M; Minami, M; Nagayasu, K; Nishitani, N; Sakimura, K; Sakurai, T; Sasase, H; Takarada, T; Wada, S; Yamanaka, A; Yanagida, J; Zhang, T1
Dijkhuizen, R; Guo, C; Homberg, JR; Karel, P; Reneman, L; Sadighi Alvandi, M; Van der Toorn, A; Vanderschuren, L; Verheij, MMM1
Cadoni, C; Corongiu, S; Dessì, C1
Austin, BP; Lacy, RT; Strickland, JC1
Bechard, AR; Knackstedt, LA1
Chen, JG; Cheng, XL; Deng, SL; Lu, HF; Wang, F; Xiao, W; Zheng, HL1
Bossert, JM; Epstein, DH; Hoots, JK; Hope, BT; Komer, LE; Lennon, VA; Madangopal, R; Shaham, Y; Tunstall, BJ; Weber, SJ1
Allain, F; Kawa, AB; Robinson, TE; Samaha, AN1
Belin, D; Belin-Rauscent, A; Cocker, PJ; Daniel, ML; Rotge, JY1
Aston-Jones, G; Pantazis, CB1
Garcia, BJ; Glass, JD; Jacobson, DA; Jones, PC; Prosser, RA; Yaw, AM1
Hernandez, NS; Schmidt, HD1
Gobin, C; Schwendt, M; Shallcross, J1
Barbosa Méndez, S; Salazar-Juárez, A1
Chen, JG; Gao, SQ; He, JG; Hu, ZL; Shen, ZC; Wang, F; Xu, JF; Zhang, H; Zhang, PW; Zhao, HH; Zheng, HL1
Barnea-Ygael, N; Keidar, L; Zangen, A; Zilkha, N1
Anholt, RRH; Baker, BM; Highfill, CA; Mackay, TFC; Stevens, SD1
Aug, I; Bregin, A; Innos, J; Mazitov, T; Philips, MA; Vasar, E1
Erdur, B; Ozen, M; Sabirli, R; Sarohan, A; Seyit, M; Turkcuer, I; Yilmaz, A1
Andolina, D; Babicola, L; D'Addario, SL; D'Amato, FR; Di Segni, M; Ielpo, D; Lo Iacono, L; Luchetti, A; Pascucci, T; Ventura, R1
Garcia-Keller, C; Gass, J; Kalivas, PW; Melton, S; Monforton, C; Smiley, C1
Buchta, WC; Garcia-Keller, C; Hines, B; Kalivas, P; Khanna, R; Moutal, A; Riegel, AC; Smith, ACW1
Bu, Q; Cen, X; Guo, W; Long, H; Tian, J; Wang, H; Zhao, Y1
Algallal, H; Allain, F; Ndiaye, NA; Samaha, AN1
Adamczyk, P; Bystrowska, B; Filip, M; Fuxe, K; Moniczewski, A; Zaniewska, M1
Brown, CA; Flores, HP; Karimi, M; Loftin, SK; Moerlein, SM; Perlmutter, JS; Tian, L; Videen, TO1
Bailey, A; Fragou, D; Kitchen, I; Kouidou, S; Kovatsi, L; Njau, S; Zanos, P1
Kalivas, P; Post, RM1
Duke, AN; Gould, RW; Nader, MA1
Barry, SM; Coleman, NT; McGinty, JF; Sun, WL; Whitfield, TW; Zelek-Molik, A1
Cason, AM; Grigson, PS1
Ford, KA; Marinelli, M; McCutcheon, JE; Pagels, NE; Wong, WC1
Bozarth, MA; Pudiak, CM2
Kariyeva, E; Peck, JA; Ranaldi, R; Wercberger, R1
Boisvert, M; Fang, J; Grigson, PS; Guan, Z; Puhl, MD1
Knackstedt, LA; Schwendt, M; Trantham-Davidson, HL1
Dieb, W; Durif, F; Hafidi, A; Ouachikh, O1
Barron, AB; Cornish, JL; Søvik, E1
Blough, BE; Fivel, PA; Kohut, SJ; Mello, NK; Rothman, RB1
Dwoskin, LP; Jordan, CJ; Kantak, KM; Somkuwar, SS1
Allen, RM; Barcomb, KM; Larson, GA; Mandt, BH; Nelson, AM; Ng, CM; Richards, TL; Rorabaugh, JM; Yamamoto, DJ; Zahniser, NR1
Ahmed, SH; Augier, E; Lenoir, M; Vouillac, C1
Assaf, Y; Ben-Moshe, H; Blumenfeld-Katzir, T; Croitoru, O; Friedman, A; Lax, E; Redlus, L; Sasson, E; Sudai, E; Yadid, G1
Alguacil, LF; Bocos, C; Castillo, CD; Morales, L; Pérez-García, C; Salas, E1
Bamba, T; Bando, K; Fukusaki, E; Horie, H; Ishii, A; Katagi, M; Miyawaki, I; Sato, T; Shima, N; Suzuki, K; Tatsuno, M; Tsuchihashi, H; Zaitsu, K1
Brown, TE; Dong, Y; Graziane, NM; Guo, C; Huang, YH; Ishikawa, M; Lee, BR; Lobo, MK; Ma, YY; Nestler, EJ; Neumann, PA; Otaka, M; Schlüter, OM; Sesack, SR; Shaham, Y; Suska, A; Wang, X; Wolf, ME1
Diberto, JF; Fish, EW; Krouse, MC; Malanga, CJ; Robinson, JE; Stringfield, SJ1
Norman, AB; Norman, MK; Tabet, MR; Tsibulsky, VL1
Blum, J; Carreiro, S; Hack, JB1
Baldaia, MA; Berro, LF; Frussa-Filho, R; Hollais, AW; Longo, BM; Marinho, EA; Oliveira-Lima, AJ; Santos, R; Wuo-Silva, R1
Martin-Fardon, R; Weiss, F2
Barbano, MF; Chefer, VI; Kramar, CP; Medina, JH; Wise, RA1
Gong, X; Liang, X; Liu, L; Wang, X; Zhang, W1
Lagorio, CH; Winger, G1
Aston-Jones, G; Beckley, JT; Deisseroth, K; Kaufling, J; Keistler, CR; Mahler, SV; McGlinchey, EM; Vazey, EM; Wilson, SP; Woodward, JJ1
Lin, ZC; Onaivi, ES; Schanz, N1
Białko, M; Filip, M; Frankowska, M; Jastrzębska, J; Nowak, E; Przegaliński, E1
Chen, HX; Gao, N; Jin, ZL; Li, XR; Li, YF; Tang, Y; Xiong, J; Zhang, JR1
Feltenstein, MW; Moorman, DE; See, RE; Waters, RP; Young, AB1
Brown, CA; Karimi, M; Loftin, SK; Perlmutter, JS; Tian, L1
Espallergues, J; Lüscher, C; O'Connor, EC; Pascoli, V; Terrier, J; Valjent, E1
Balster, RL; Henningfield, JE; Nader, MA1
Ahmed, SH; Guillem, K; Navailles, S; Vouillac-Mendoza, C1
Janiuk, I; Kasacka, I; Piotrowska, Z; Zbucki, R1
Cosme, CV; Du, J; Fan, R; Ghobbeh, A; Kreple, CJ; LaLumiere, RT; Lu, Y; Radley, JJ; Schwager-Gutman, AL; Sowers, LP; Stump, M; Taugher, RJ; Wang, Y; Welsh, MJ; Wemmie, JA1
Bhide, PG; Kabir, ZD; Kosofsky, BE; McCarthy, DM1
Bali-Chaudhary, S; Chang, CY; Hoffman, AF; Lucantonio, F; Lupica, CR; Schoenbaum, G; Shaham, Y; Takahashi, YK1
Aston-Jones, G; Bentzley, BS; Jhou, TC1
Calcagno, N; Huizenga, MN; Kay, K; Pierce, RC; Rasakham, K; Sadri-Vakili, G; Schmidt, HD; Spires-Jones, TL1
Golebiowska, J; Kregiel, J; Kubik, J; Popik, P; Rygula, R; Szczech, E1
Cai, X; Ellis, BA; Eubanks, LM; Janda, KD; Schlosburg, JE1
Carroll, ME; Zlebnik, NE1
Fadda, P; Fattore, L; Fratta, W; Zanda, MT1
Kandel, D; Kandel, E1
Alexander, DN; Anosike, N; Ballard, SM; Carter, AB; Cox, TA; Freet, CS; Grigson, PS; Imperio, CG; Mahmoud, S; Ruiz-Velasco, V1
Li, X; Wolf, ME1
Chung, M; Heintzelman, KL; Kufahl, PR; Neisewander, JL; Peartree, NA1
Broekhoven, MH; Damsteegt, R; Limpens, JH; Vanderschuren, LJ; Voorn, P1
Cunningham, KA; Howell, LL1
Chauvet, C; Duranti, A; Lardeux, MV; Nicolas, C; Solinas, M; Thiriet, N1
Belzung, C; Castelnau, P; Chalon, S; Cortese, S; Emond, P; Faraone, SV; Galineau, L; Lepelletier, FX; Nicolas, C; Solinas, M; Tauber, C1
Eisenstein, SA; McGinty, JF; Sun, WL; Zelek-Molik, A1
Adrover, MF; Alvarez, VA; Bock, R; Fuino, RL; Gremel, CM; Holroyd, KB; Kaplan, AR; Rubinstein, M1
Clementz, MA; Jablonski, J; McLaughlin, JP; Mediouni, S; Paris, JJ; Thenin-Houssier, S; Valente, ST1
Craige, CP; Kirby, LG; Lewandowski, S; Unterwald, EM1
Beveridge, TJ; Nader, MA; Porrino, LJ; Smith, HR2
Eagle, AL; Enman, NM; Friedman, AL; Galloway, MP; Jutkiewicz, EM; Kohler, RJ; Liebowitz, CP; Perrine, SA; Singh, R1
Bérod, A; Denoroy, L; El Yacoubi, M; Morel, AL; Rappeneau, V; Vaugeois, JM1
Beloate, LN; Freeman, KB; Huskinson, SL; Roma, PG; Townsend, EA1
Childers, SR; Hemby, SE; McIntosh, S; Pattison, LP; Sexton, T1
Chen, L; Napier, TC; Persons, AL; Wayman, WN1
Davidson, C; Hutchinson, CV; Prados, J1
Bordia, T; Drenan, RM; McGregor, M; McIntosh, JM; Quik, M1
Boger, HA; Haydon, PG; Kalivas, PW; Li, H; Scofield, MD; Smith, RJ1
Ambrósio, AF; Baptista, S; Gonçalves, J; Martins, J; Silva, AP1
Pierce, RC; Schmidt, HD; Vassoler, FM; White, SL; Wimmer, ME1
Bills, SE; Lacy, RT; Smith, MA; Strickland, JC1
Balter, R; Evans, SM; Foltin, RW; Haney, M; Reed, SC; Rubin, E; Vadhan, N1
Hafenbreidel, M; Mueller, D; Rafa Todd, C; Twining, RC1
Dhungana, S; Goeders, NE; Guerin, GF; Runyon, SP; Schmoutz, CD1
Caffino, L; Fumagalli, F; Giannotti, G; Malpighi, C; Racagni, G1
Cahill, CM; Castonguay, A; Cook, C; De Koninck, Y; Evans, CJ; Ghogha, A; Murphy, NP; Olmstead, MC; Taylor, AJ; Taylor, AM; Xue, L1
Christian, DT; Loweth, JA; Milovanovic, M; Werner, CT; Wolf, ME1
Bernstein, DL; Brodnik, ZD; España, RA; Prince, CD1
Berro, LF; Borçoi, AR; Ceccon, LM; Frussa-Filho, R; Grapiglia, SB; Hollais, AW; Lopes-Silva, LB; Patti, CL; Ribeiro, LT; Santos-Baldaia, R; Wuo-Silva, R; Zanin, KA1
Arango-Lievano, M; Kaplitt, MG1
Dietz, DM; Dossat, AM; Duclot, F; Feng, J; Francis, TC; Hollis, F; Kabbaj, M; Lobo, MK; Mercer, R; Nestler, EJ; Strong, CE; Wright, KN1
Dixit, D; Jung, JB; Kim, IJ; Kim, SG; Lowe, EL; Rovner, R; Vatakis, DN; Youn, CS; Zack, JA1
Del Olmo, N; Fole, A; Martin, M; Morales, L1
Arthur, K; Enman, NM; Perrine, SA; Unterwald, EM; Ward, SJ1
Friedman, SH; Kalb, RG; Neve, RL; Ortinski, PI; Pierce, RC; Schmidt, HD; White, SL; Zhang, L1
Cryan, JF; Glennon, J; Moloney, RD; O'Connor, RM; Vlachou, S1
Boughner, E; Cummins Jacklin, E; Kent, K; Kwiatkowski, D; Leri, F; MacDonald, T1
Marinelli, M; Wong, WC1
García-Cabrerizo, R; García-Fuster, MJ; Keller, B1
Al Sweidi, S; Bourque, M; Caruso, D; Di Paolo, T; Melcangi, RC; Morissette, M1
Godfrey, JR; Manvich, DF; Stowe, TA; Weinshenker, D1
Aguiar, DC; Crippa, JA; de Oliveira, AC; Gobira, PH; Gonçalves, BD; Moreira, FA; Santos, RP; Vieira, LB; Vilela, LR1
Carroll, ME; Holtz, NA; Radke, AK; Zlebnik, NE1
Trujols, J1
Labouesse, MA; Langhans, W; Meyer, U1
Gerhardt, GA; Kellaway, LA; Russell, VA; Stein, DJ; Womersley, JS1
Barnea, R; Bekker, L; Marco, A; Weller, A; Yadid, G; Zifman, N1
Dwoskin, LP; Jordan, CJ; Kantak, KM; Taylor, DM1
Alvarsson, A; Kadkhodaei, B; Millan, MJ; Perlmann, T; Schintu, N; Stan, TL; Svenningsson, P; Zhang, X1
Gomez, AM; Midde, NM; Quizon, PM; Sun, WL; Yuan, Y; Zhan, CG; Zhu, J1
dos Santos Pereira, M; Fraga, MC; Kubrusly, R; Manhães, AC; Marques, RS; Peccinalli, NR; Sathler, MF; Valli, Tda R; Ventura, AL1
Castilla-Ortega, E; Estivill-Torrús, G; Ladrón de Guevara-Miranda, D; Pavón, FJ; Rivera, P; Rodríguez de Fonseca, F; Santín, LJ; Serrano, A; Suárez, J1
Hiver, A; Lüscher, C; Pascoli, V; Terrier, J1
Cao, C; Guan, X; Guan, Y; Li, M; Mao, Z; Xie, G; Yuan, J; Zhu, C; Zhu, W1
Caille, S; Diana, M; Faure, P; Fois, GR; Georges, F; Glangetas, C; Jalabert, M; Lecca, S; Mameli, M; Meye, FJ; Valentinova, K1
Kirby, LG; Li, C1
Ben-Shahar, O; Kippin, TE; Miller, BW; Sacramento, AD; Shin, CB; Silva, HE; Szumlinski, KK; Vieira, PA; Wroten, MG1
Butelman, ER; Kreek, MJ; Picetti, R; Valenza, M; Yuferov, V1
Clark, JK; Keefe, K; Kesner, RP; Kirk, RA; Moore, A1
de Carvalho, CR; Takahashi, RN1
Bi, GH; Bonci, A; Gao, M; Gardner, EL; Liu, QR; Shen, H; Wu, J; Xi, ZX; Yang, HJ; Zhang, HY1
Caffino, L; Cervo, L; Di Clemente, A; Fumagalli, F; Giannotti, G; Govoni, S; Moro, F; Osera, C; Pascale, A1
Aricò, E; Bisicchia, E; Carola, V; Castiello, L; D'Amato, FR; Ermakova, O; Lo Iacono, L; Oddi, D; Puglisi-Allegra, S; Valzania, A; Visco-Comandini, F; Viscomi, MT1
de Moura, FB; McMahon, LR1
Aston-Jones, G; Bentzley, BS1
Bye, CR; Ganella, DE; Kim, JH; Lawrence, AJ; Madsen, HB; Perry, CJ; Zbukvic, IC1
Cowan, CW; Penrod, RD; Smith, LN; Taniguchi, M1
Ferland, JN; Winstanley, CA1
Ambrosio, E; Borcel, É; Capellán, R; Higuera-Matas, A; Orihuel, J; Roura-Martínez, D; Santos-Toscano, R; Ucha, M1
Abel, J; Beiter, RM; Lynch, WJ; Peterson, AB1
Chai, PR; Hack, JB1
Bogyo, K; Ettenberg, A; Schick, T; Shelton, K1
Aguilar, MA; Guerri, C; Miñarro, J; Montagud-Romero, S; Montesinos, J; Pascual, M; Rodríguez-Arias, M; Roger-Sanchez, C1
Hadad, NA; Hiller, H; Knackstedt, LA; Krause, EG; Schwendt, M; Wu, L1
Burke, AR; DeBold, JF; Miczek, KA1
Clancy, PT; Lim, YW; Muelbl, MJ; Nawarawong, NN; Nettesheim, CE; Olsen, CM1
Berini, CR; Ghee, SM; Leong, KC; Reichel, CM1
Monsey, MS; Sanchez, H; Taylor, JR1
Ferrario, CR; Goforth, PB; Lopez-Santiago, LF; Nobile, CW; Oginsky, MF1
Andersen, SL; Freund, N; Lukkes, JL; Meda, S; Thompson, BS1
Aguilar, MA; Guerri, C; Miñarro, J; Montagud-Romero, S; Pascual, M; Reguilon, MD; Rodríguez-Arias, M; Roger-Sanchez, C1
Izenwasser, S; Reed, SC1
Arguello, AA; Fuchs, RA; Hall, JL; Hodges, MA; Mitchell, MP; Richardson, BD; Rossi, DJ; Stuber, GD; Wang, R1
Cosme, CV; Ewald, VA; Gutman, AL; LaLumiere, RT; Worth, WR1
Calò, G; Ciccocioppo, R; de Guglielmo, G; Kallupi, M; Rorick-Kehn, LM; Scuppa, G; Statnick, MA; Weiss, F1
Galaj, E; Harding, W; Ranaldi, R1
Aguilar, MA; Arenas, MC; Gutiérrez, MS; Manzanares, J; Manzanedo, C; Mateos-García, A; Miñarro, J; Navarrete, F; Rodríguez-Arias, M1
Bailey, B; Bania, TC; Bhalla, A; Calello, DP; Chuang, R; Gosselin, S; Graudins, A; Hayes, BD; Hoegberg, LC; Hoffman, RS; Lavergne, V; Levine, M; Mégarbane, B; Morris, M; Nesbitt-Miller, A; Stellpflug, SJ; Stork, CM; Thomas, SH; Turgeon, AF1
Bell, RL; Breier, A; Chambers, RA; Engleman, EA; Hulvershorn, LA; Rao, KN; Sentir, AM1
Crofton, EJ; Fan, X; Green, TA; Kong, F; Li, D; Lichti, CF; Luxon, BA; Sinha, M; Spratt, HM; Zhang, Y1
Guo, F; Huang, L; Liu, N; Liu, Y; Lu, K; Tu, G; Ying, L; Zhang, L; Zhao, J; Zhu, M1
Crouzin, N; Fuentes, S; Hoffmann, HM; McCormick, PJ; Moreno, E; Ortiz, J; Raivio, N; Vignes, M1
Bell, GA; Bhide, PG; Cannon, EN; Fadool, DA; Huizenga, MN; McCarthy, DM; Mueller, KA; Sadri-Vakili, G1
Jones, SR; Siciliano, CA1
Dunbar, AB; Taylor, JR1
Caffino, L; Fumagalli, F; Giannotti, G; Racagni, G1
Akil, H; Flagel, SB; García-Fuster, MJ; Parsegian, A; Watson, SJ1
Bordia, T; Perez, XA; Quik, M; Zhang, D1
Bagdas, D; Carroll, FI; Damaj, MI; Greenwald, M; Jackson, A; Lichtman, AH; Miles, MF; Muldoon, PP1
Meyer, AE; Miller, MM; Sable, HJ; Sprowles, JL1
Akil, H; Clinton, SM; García-Fuster, MJ; Watson, SJ1
Connor, DF; Melloni, RH; Morrison, RL; Ricci, LA; Schwartzer, JJ1
Balado, E; Belin, D; Deroche-Gamonet, V; Piazza, PV1
Steketee, JD; Xie, X1
Heberlein, U; Kapfhamer, D; Lasek, AW; Tsai, LT1
Bubar, MJ; Cunningham, KA1
Heard, K; Krier, S; Zahniser, NR1
Aunis, D; Gobaille, S; Host, L; Romieu, P; Sandner, G; Zwiller, J1
Alexander, M; Burton, NC; Griswold, M; Guilarte, TR; McGlothan, JL; Pham, L; Schneider, JS; Syversen, T; Verina, T; Wong, DF; Zhou, Y1
Hazim, R; Jenab, S; Quinones-Jenab, V; Sun, WL; Zhou, L1
Dziedzicka-Wasylewska, M; Faron-Górecka, A; Filip, M; Frankowska, M; Kuśmider, M; Wydra, K; Zaniewska, M1
Cha, JH; Famous, KR; Kumaresan, V; Mierke, DF; Pierce, RC; Sadri-Vakili, G; Schmidt, HD1
Cowan, CW; Hale, CF; Taniguchi, M1
Brim, R; Gao, D; Ko, MC; Landry, DW; Macdonald, J; Narasimhan, DL; Sunahara, RK; Woods, JH; Zhan, CG1
Baladi, MG; Cooper, ZD; Jutkiewicz, EM; Narasimhan, D; Sunahara, RK; Woods, JH1
Caron, MG; Keene, JD; Tiruchinapalli, DM1
Bachtell, RK; Self, DW1
Melloni, RH; Morrison, RL; Ricci, LA; Schwartzer, JJ1
Kalivas, PW; Pacchioni, AM; Wiggins, AT1
Ghasemzadeh, MB; Mantsch, JR; Mueller, C; Seubert, C; Vasudevan, P1
Hsu, KS; Huang, CC; Lee, CC; Liang, YC; Wu, MY1
Bordia, T; Huang, LZ; Michael McIntosh, J; Parameswaran, N; Quik, M1
Iida, A; Inoue, N; Kakiuchi, T; Kondo, Y; Muramatsu, S; Nakano, I; Nakayama, T; Okuno, T; Ono, F; Suzuki, Y; Takino, N; Terao, K; Tsukada, H1
Self, DW; Simmons, D1
Ary, AW; Ben-Shahar, O; Ma, N; Mangiardi, MA; Medina, RL; Obara, I; Szumlinski, KK1
Frantz, KJ; Li, C1
Cunningham, KA; Fox, RG; Nic Dhonnchadha, BA; Rice, KC; Stutz, SJ1
Ford, KA; Hu, XT; Wolf, ME1
Banks, ML; Fantegrossi, WE; Goeders, JE; Murnane, KS1
Huang, X; Xiao, D; Xu, Z; Yang, S; Zhang, L1
Alguacil, LF; Alonso, E; del Castillo, C; Garrido, E; Morales, L; Pérez-García, C; Salas, E1
Boudreau, AC; Ferrario, CR; Glucksman, MJ; Wolf, ME1
Schumann, J; Yaka, R1
Deadwyler, SA; Hampson, RE; Opris, I1
Dickey, ED; Joyce, JN; Kufahl, PR; Neisewander, JL; Singh, A; Thiel, KJ; Zavala, AR1
Feng, Z; Walker, VJ; Ward, A; Xu, XZ1
Gardner, EL; Kiyatkin, M; Li, J; Li, X; Peng, XQ; Spiller, K; Wiggins, A; Xi, ZX1
Cleveland, NR; Heard, KJ; Krier, S2
Di Paolo, T; Grégoire, L; Lévesque, D; Morissette, M; Ouattara, B; Rouillard, C; Samadi, P; Tamim, MK1
Aston-Jones, G; Smith, RJ; Tahsili-Fahadan, P1
Abraham, L; Dikshtein, Y; Flaumenhaft, Y; Friedman, A; Lax, E; Roth-Deri, I; Yadid, G1
Berkow, A; Bossert, JM; Farquhar, D; Ghosh, SC; Golden, SA; Guez-Barber, DH; Harvey, BK; Hope, BT; Koya, E; Marin, MT; Mattson, BJ; Mitchell, TB; Nair, SG; Simmons, DE; Uejima, JL1
Adams, W; Ayton, S; van den Buuse, M1
Dezfouli, A; Ekhtiari, H; Keramati, MM; Lucas, C; Mokri, A; Piray, P1
Di Paolo, T; Gilbert, F; Grégoire, L; Lévesque, D; Mahmoudi, S; Morissette, M; Ouattara, B; Rouillard, C; Samadi, P1
Acosta, JI; Browning, JR; Hamilton, EC; Neisewander, JL; Pentkowski, NS1
Dykstra, LA; Rosenberg, M; Walker, EA; Ward, SJ1
Anker, JJ; Carroll, ME; Gliddon, LA; Zlebnik, NE1
Alibhai, IN; Bardo, MT; Bass, CE; Birnbaum, SG; Graham, AR; Graham, DL; Green, TA; Nestler, EJ; Roybal, CN; Terwilliger, EF; Theobald, DE; Unterberg, S; Vialou, V; Winstanley, CA1
Kalivas, PW; Knackstedt, LA; Melendez, RI1
Larson, GA; Nelson, AM; Zahniser, NR1
Aguilar, MA; Daza-Losada, M; Miñarro, J; Rodríguez-Arias, M1
Fadda, P; Fattore, L; Fratta, W1
Aubier, B; Bertran-Gonzalez, J; Girault, JA; Greengard, P; Hervé, D; Valjent, E1
Fuchs, RA; Lasseter, HC; Ramirez, DR; Xie, X1
Belcher, AM; Cazares, VA; Chen, J; Izquierdo, A; Malvaez, M; Marshall, JF; O'Dell, SJ; Scott, L; Wu, T1
Buffalari, DM; See, RE1
Kuhar, MJ1
Aguiar, LM; Andrade-Neto, M; Belchior, LD; de Sousa, FC; Fonteles, MM; Gonçalves, DO; Honório Júnior, JE; Macêdo, DS; Silva, MI; Vasconcelos, SM; Viana, GS1
Ambrose-Lanci, LM; Sterling, RC; Van Bockstaele, EJ1
Jia, J; Li, B; Liu, L; Sun, Z; Tian, J; Wang, X; Wang, Y; Zhang, J1
Bowman, TA; Knuepfer, MM; Kucenas, S; Ruhlman, M; Watanabe, MA1
Howell, JL; Krueger, DD; Nairn, AC; Olausson, P; Oo, H; Taylor, JR1
Goodman, MM; Howell, LL; Lindsey, KP; Votaw, JR1
Abílio, VC; Correia-Pinto, JC; Cunha, JL; Frussa-Filho, R; Kameda, SR; Levin, R; Niigaki, ST; Patti, CL; Silva, RH; Takatsu-Coleman, AL1
Anker, JJ; Carroll, ME4
Cui, FJ; Hwang, JY; Kang, UG; Park, HJ1
Dow-Edwards, D1
Czoty, PW; Gage, HD; Nader, MA1
Levitt, P; Stanwood, GD; Thompson, BL1
Akil, H; Clinton, SM; García-Fuster, MJ; Perez, JA; Watson, SJ1
Bradberry, CW2
Keyghobadi, M; McKee, BL; Meshul, CK; Tozier De La Poterie, AP1
Kurokawa, K; Ohkuma, S; Shibasaki, M1
Brucklacher, RM; Freeman, WM; Lull, ME; Morgan, D; Patel, KM; Roberts, DC; Vrana, KE1
Ekwedike, NN; Gilloteaux, J1
Hall, FS; Igari, M; Ikeda, K; Li, B; Sora, I1
Buccafusco, JJ; Hall, BJ; Pearson, LS1
Centeno, M; Fu, Y; Gallagher, JP; Genzer, K; Krishnan, B; Liu, J; Pollandt, S; Shinnick-Gallagher, P1
Ahmed, SH2
Chavkin, C; Li, S; Schindler, AG1
Alenina, N; Bader, M; Filip, M; Przegaliński, E1
Almansa, I; Barcia, JM; López-Pedrajas, R; Muriach, M; Romero, FJ; Sanchez-Villarejo, MV1
Hayashi, T; Saiki, H; Takahashi, J; Takahashi, R1
De Montis, MG; Gambarana, C; Grappi, S; Marchese, G; Scheggi, S; Secci, ME1
Balado, E; Berson, N; Deroche-Gamonet, V; Kasanetz, F; Lafourcade, M; Manzoni, O; Piazza, PV1
Ahrens, A; Duvauchelle, CL; Ma, ST; Maier, EY; Schallert, TJ1
Anker, JJ; Carroll, ME; Zlebnik, NE1
Arolfo, M; Blackburn, B; Chu, N; Diamond, I; Fan, P; Jiang, Z; Kim, HY; Lee, J; Leung, K; Olive, MF; Shryock, J; Sun, HL; Yao, L; Zablocki, J1
Balest, ZR; Corotto, FS; Lloyd, SA; Smeyne, RJ1
Cheng, PL; Khoshnevisrad, N; Lim, BK; Lu, H; Poo, MM1
Chun, L; Froimowitz, M; Gardner, EL; Li, J; Li, X; Peng, XQ; Spiller, K; Wu, KM; Xi, ZX1
Gao, S; Nakahara, D; Nakamura, M; Okamura, H1
Neisewander, JL; Painter, MR; Peartree, NA; Pentkowski, NS; Thiel, KJ1
Fricks-Gleason, AN; Marshall, JF1
Czoty, PW; Gould, RW; Martelle, JL; Nader, MA1
Glick, SD; Huang, Y; McCallum, SE; Wu, J1
Balado, E; Belin, D; Berson, N; Deroche-Gamonet, V; Piazza, PV1
Cami-Kobeci, G; Husbands, SM; Khroyan, TV; Polgar, WE; Toll, L; Zaveri, NT1
Brown, ZJ; Erb, S; Kupferschmidt, DA1
Chandrasekar, V; Dreyer, JL1
Suto, N; Vezina, P; Wise, RA1
Bellone, C; Brown, MT; Lüscher, C; Mameli, M1
Alguacil, LF; Ambrosio, E; Del Olmo, N; Fole, A; González-Martín, C; Huarte, C1
Cleveland, NR; Heard, K; Krier, S2
Fields, HL; King, T; Lai, J; Okun, A; Porreca, F; Qu, C1
Duysen, EG; Lockridge, O1
Mueller, D; Otis, JM1
Kovács, KJ; Larson, AA; McElhose, A; Thomas, MJ1
Black, YD; Hanlin, RP; Konradi, C; Naydenov, AV; Sillivan, SE; Vassoler, FR1
Ahmed, SH; Koob, GF; Mihindou, C; Vouillac, C1
Adams, RJ; Clements, JE; Hienz, RD; Linde, ME; Mankowski, JL; Meulendyke, KA; Weed, M; Zink, MC1
Debold, JF; Holly, EN; Miczek, KA; Shimamoto, A1
Hrubá, L; Pometlová, M; Schutová, B; Slamberová, R1
Doering, LC; Farncombe, TH; Gleave, JA; Saab, C1
Carlezon, WA; Chartoff, E; Pliakas, A; Potter, D; Rachlin, A; Sawyer, A1
Cao, L; Guo, QY; Wang, XM; Wang, XY; Zhang, YF1
Carmichael, B; Cummins, E; Kreek, MJ; Leri, F; Zhou, Y1
Jakovcevski, M; Morellini, F; Schachner, M1
Knackstedt, LA; Sondheimer, I1
Dobrin, CV; Roberts, DC; Zimmer, BA1
Arora, D; Fajardo-Serrano, A; Haluk, DM; Hearing, M; Luján, R; Mirkovic, K; Watanabe, M; Wessendorf, MW; Wickman, K1
Abdalla, M; Ahrens, AM; Duvauchelle, CL; Maier, EY; Schallert, T1
Crystal, RG; De, BP; Hicks, MJ; Janda, KD; Kaminsky, SM; Koob, GF; Moreno, AY; Rosenberg, JB; Wee, S1
Alvaro-Bartolomé, M; Callado, LF; García-Sevilla, JA; La Harpe, R; Meana, JJ1
Barker, DJ; Fabbricatore, AT; Ma, S; Pawlak, AP; Root, DH; West, MO1
Ambrosio, E; Botreau, F; Coria, SM; Del Olmo, N; Higuera-Matas, A; Miguéns, M; Olías, O1
Kurokawa, K; Mizuno, K; Ohkuma, S; Shibasaki, M1
Bernardi, G; Castelli, M; Centonze, D; De Chiara, V; Federici, M; Gu, HH; Mercuri, NB; Motta, C; Musella, A; Napolitano, F; Romano, R; Rossi, S; Sacchetti, L; Siracusano, A; Studer, V; Usiello, A1
Alstrup, AK; Doudet, DJ; Gjedde, A; Høltzermann, M; Jakobsen, S; Landau, AM; Møller, A; Nahimi, A; Simonsen, M; Vang, K; Wegener, G1
Booze, RM; Mactutus, CF; Patel, DA1
Du, C; Pan, Y; Park, K; Ren, H; Volkow, ND; Yuan, Z1
Blaylock, BL; Nader, MA1
Bachtell, RK; LeTendre, ML; O'Neill, CE1
Bing, G; Cao, T; Gerhardt, GA; Hinzman, JM; Lifshitz, J; Liu, M; Pauly, JR; Thomas, TC; van Bregt, DR1
Belin, D; Dalley, JW; Dilleen, R; Everitt, BJ; Mar, AC; Molander, A; Pelloux, Y; Robbins, TW1
Burokas, A; Gutiérrez-Cuesta, J; Maldonado, R; Martín-García, E1
Kiyatkin, EA; Mejías-Aponte, CA1
Barber, JS; Enns, JA; Jamieson-Drake, AW; Johns, JM; Townsend, LB; Walker, CH; Williams, SK1
Kalivas, PW; Knackstedt, L; Moussawi, K; Shen, H; Wang, X1
Devineni, AV; Heberlein, U; Kaun, KR1
Hutchison, MA; Riley, AL1
Bengtsen, CH; Christiansen, SH; Dencker, D; Fink-Jensen, A; Jensen, M; Loland, CJ; Petersen, JH; Sørensen, G; Weikop, P; Woldbye, DP; Wörtwein, G1
Ball, WJ; Norman, AB1
Aalkjaer, C; Boedtkjer, DB; Bouzinova, EV; Broegger, T; Matchkov, VV; Møller-Nielsen, N; Wiborg, O1
Goodman, MM; Howell, LL; Kimmel, HL; Mun, J; Nye, JA; Rice, KC; Sawyer, EK; Stehouwer, JS; Voll, RJ1
Buch, S; Yao, H1
Choi, SM; Jang, EY; Kim, HY; Lee, BH; Steffensen, SC; Yang, CH; Yang, EJ; Yoon, SS1
Abbott, LC; Finnell, RH; Hill, DS; Mendez, IA; Setlow, B; Wallis, D; Wellman, PJ1
Balado, E; Berson, N; Deroche-Gamonet, V; Fiancette, JF; Kasanetz, F; Lafourcade, M; Manzoni, OJ; Piazza, PV; Renault, P; Revest, JM1
Bradaia, A; Bruns, A; Buchy, D; Chaboz, S; Galley, G; Groebke Zbinden, K; Hoener, MC; Kilduff, TS; Metzler, V; Morairty, SR; Moreau, JL; Mory, R; Norcross, RD; Pouzet, B; Revel, FG; Risterucci, C; Tuerck, D; Wallace, TL; Wettstein, JG1
Engleman, EA; Musselman, HN; Nass, R; Neal-Beliveau, B1
Chefer, S; Guillem, K; Kurup, PK; Lu, H; Moore, A; Peoples, LL; Ross, TJ; Stein, EA; Vaupel, DB; Yang, Y1
Burger, A; Hammond, S; Seymour, CM; Wagner, JJ1
Belin, D; Everitt, BJ; Murray, JE1
Dilleen, R; Economidou, D; Everitt, BJ; Pelloux, Y; Theobald, D1
Bergman, J; Blaylock, BL; Nader, MA; Newman, AH; Sibley, DR; Skolnick, P1
Abramowitz, AC; Cox, ET; Hodge, CW; Jamieson-Drake, AW; Johns, JM; Jones, GF; Makam, PR; Sheikh, MJ; Zeskind, PS1
Czoty, PW; Morgan, D; Nader, MA; Nader, SH1
Gaál, J; Gardner, EL; Li, J; Li, X; Peng, XQ; Song, R; Xi, ZX1
Monteil, C; Mulder, P; Thuillez, C; Vendeville, C; Ventura-Clapier, R; Vergeade, A1
Baker, DA; Kau, KS; Kong, L; Lutgen, V; Madayag, A; Mantsch, JR1
Blaha, CD; Dickson, PE; Miller, MM; Mittleman, G; Rogers, TD1
Degirmenci, E; Erdur, B; Ergin, A; Kortunay, S; Seyit, M; Yuksel, A1
Karlsson, RM; Kircher, DM; O'Donnell, P; Shaham, Y1
Aston-Jones, G; Fallon, RV; Hensley-Simon, M; Kalivas, PW; LaLumiere, RT; Mahler, SV; Tahsili-Fahadan, P; Thomas, C1
Benturquia, N; Noble, F; Puig, S1
Anderson, BJ; Heyman, G; Robinson, JK; Robison, LS; Stamos, J; Thanos, PK; Tucci, A; Volkow, ND; Wang, GJ1
Belin, D; Deroche-Gamonet, V1
Dankoski, EC; Fish, EW; Han, JE; Hodge, CW; Krouse, MC; Malanga, CJ; Philpot, BD; Riday, TT; Walsh, PL; Wightman, RM1
Badiani, A; De Luca, MT; Meringolo, M; Spagnolo, PA1
Grigson, PS; Nyland, JE1
Burgeno, LM; Everitt, BJ; Phillips, PE; Willuhn, I1
Pierce, RC; Sadri-Vakili, G; Schmidt, HD; Vassoler, FM; White, SL1
Deschaux, O; Diaz-Aguilar, L; George, O; Koob, GF; Mandyam, CD; Schlosburg, JE; Sobieraj, JC; Vendruscolo, LF; Yuan, CJ1
Crossman, AR; Kobylecki, C; Ravenscroft, P1
Dalley, JW; Everitt, BJ; Ito, R; Robbins, TW1
Guan, XW; He, W; Ren, JQ; Song, J1
Inoue, O; Kagawa, S; Nakano, T; Nishimura, T1
Hargrave, B; Lattanzio, F1
Kalivas, PW; McGinty, JF; Toda, S1
Nishikawa, T1
Davidson, C; Ellinwood, EH; Lee, TH; Xiong, Z1
Coufal, NG; Goulding, EH; Mead, AN; O'Dell, LE; Parsons, LH; Rocha, BA; Tecott, LH1
Izzo, E; Koob, GF; Martin-Fardon, R; Sanna, PP; Weiss, F1
Heberlein, U; Wolf, FW1
Mathier, MA; Shannon, RP; Shen, YT2
Grimm, JW; Hayashi, T; Hope, BT; Lu, L; Shaham, Y; Su, TP1
Avila, AH; Bayer, BM; Morgan, CA1
Colby, CR; Nestler, EJ; Self, DW; Steffen, C; Whisler, K1
Hotsenpiller, G; Wolf, ME1
Cohn, SI; Kearns, DN; Panlilio, LV; Schindler, CW; Weiss, SJ1
Kalivas, PW; Lake, R; Ramamoorthy, S; Samuvel, DJ; Shen, H; Xi, ZX1
Kalivas, PW; Lapish, CC; McFarland, K1
Fuchs, RA; Middaugh, LD; See, RE1
Grimm, JW; Hope, BT; Lu, L; Shaham, Y1
Aouizerate, B; Deroche-Gamonet, V; Ghozland, S; Izawa, R; Jaber, M; Kellendonk, C; Le Moal, M; Piazza, PV; Schütz, G; Sillaber, I; Spanagel, R; Tronche, F1
Ahmed, SH; Koob, GF; Lin, D; Parsons, LH1
Haase, C; Hoit, BD; Lewis, W; Morris, R; Norman, AB; Russ, R; Sutliff, RL1
De Montis, MG; Grappi, S; Leggio, B; Masi, F; Nanni, G; Rauggi, R; Scheggi, S1
Eikelboom, R; Lattanzio, SB1
Koeltzow, TE; White, FJ1
Camí, J; Farré, M1
Girlanda, E; Heidbreder, CA; Lennon, M; Mugnaini, M; Sartori, I; Varnier, G; Wildish, GA; Zanetti, L; Zocchi, A1
Hicks, AR; Ogden, BA; Varner, KJ1
France, CP; McMahon, LR; Sell, SL1
De Vries, TJ; Homberg, JR; Raasø, HS; Schoffelmeer, AN; Wardeh, G1
Ahmed, SH; Ben-Shahar, O; Ettenberg, A; Koob, GF1
Bloodgood, TA; Knuepfer, MM; Lechner, AJ; Matuschak, GM1
Ding, H; He, L; Kuang, A; Ye, B; Yuan, Q; Zheng, H1
Tashkin, DP1
Davidge, SB; Kalivas, PW; Lapish, CC; McFarland, K1
Bossert, JM; Dempsey, J; Liu, SY; Lu, L; Shaham, Y1
Carroll, FI; Goodman, MM; Howell, LL; Lindsey, KP; Plisson, C; Rice, KC; Votaw, JR; Wilcox, KM1
Morgan, D; Roberts, DC1
Everitt, BJ; Ito, R; Robbins, TW1
Leri, F; Sorge, RE; Stewart, J; Tremblay, A1
Dempsey, J; Lu, L1
Kalra, PS; Kalra, SP; Keen Rhinehart, E1
Baumann, MH; Milchanowski, AB; Rothman, RB1
Krisch, I; Milivojevic, N; Sket, D; Zivin, M1
Freeman, WM; Hemby, SE; Liang, B; Tang, W; Wesley, M1
Post, RM2
Gosnell, BA; Swant, J; Thompson, AM; Wagner, JJ1
Raffa, RB; Stagliano, GW; Umeda, S1
De Montis, MG; Gambarana, C; Rauggi, R; Scheggi, S; Tagliamonte, A1
Badiani, A; Robinson, TE1
Barros, HM; Lucion, AB; Marquardt, AR; Ortiz-Lemos, L1
Goldfrank, LR; Hoffman, RS; Hung, OL; Kaplan, JL1
Belluzzi, JD; Leslie, FM; Wang, R1
Ettenberg, A; Guzman, D1
Bergman, J; Gasior, M; Kallman, MJ; Paronis, CA1
Festa, ED; Quinones-Jenab, V1
Hirsh, J; Lease, KA1
Bossert, JM; Dempsey, J; Hope, BT; Liu, SY; Lu, L; Shaham, Y1
Burbach, JP; Gerrits, MA; Kamal, A; Lesscher, HM; Mathon, DS; Pintar, JE; Ramakers, GM; Schuller, AG; Smidt, MP; Spruijt, BM; van Ree, JM1
Brady, RO; Cho, A; Greengard, P; Iadarola, MJ; Kim, Y; Kulkarni, AB; Nairn, AC; Ohshima, T; Pant, HC; Sreenath, T; Takahashi, S1
Desai, P; Raffa, RB1
Carey, RJ; Damianopoulos, E; DePalma, G; Huston, JP; Müller, CP; Shanahan, A1
Bai, J; He, F; Lidow, MS; Novikova, SI1
Biala, G1
Andersen, ML; Tufik, S1
Fagergren, P; Goiny, M; Hurd, YL; Overstreet, DH1
Cleveland, NJ; Dewitt, CD; Heard, K1
Boguslavsky, Y; Green-Sadan, T; Kinor, N; Kuttner, Y; Lublin-Tennenbaum, T; Margel, S; Yadid, G1
Bailey, A; Bendor, J; Ho, A; Kreek, MJ; Schlussman, SD; Yuferov, V; Zhou, Y1
Dickerson, TJ; Janda, KD; Kaufmann, GF1
Liu, Y; Morgan, D; Roberts, DC1
Castañé, A; Ledent, C; Maldonado, R; Parmentier, M; Soria, G; Valverde, O1
Hamby, SM; McCracken, CB; Morgan, D; Patel, KM; Roberts, DC; Vrana, KE1
Baldwin, GC; Choi, R; Roth, MD; Tashkin, DP; Whittaker, KM1
Bainton, RJ; DeSalvo, M; Gaul, U; Heberlein, U; Schwabe, T; Tsai, LT1
Arvanitogiannis, A; Augustyniak, PN; Kourrich, S; Rezazadeh, SM; Stewart, J1
Griffin, WC; Middaugh, LD1
Berglind, WJ; Case, JM; Fuchs, RA; Parker, MP; See, RE1
Choi, KH; Graham, DL; Self, DW; Whisler, K1
Steiner, H; Willuhn, I1
Brambilla, R; Fasano, S; Ferguson, SM; Robinson, TE; Yang, P1
Cannon, DG; Kahn, W; Martin, TJ; Smith, JE1
Dziedzicka-Wasylewska, M; Faron-Górecka, A; Filip, M; Frankowska, M; Gołda, A; Kuśmider, M1
Cagle, S; Kalivas, PW; Peters, J; Shen, HW; Toda, S1
Becker, N; Mead, AN; Stephens, DN; Zamanillo, D1
Edwards, S; Fuller, DC; Orsulak, PJ; Self, DW; Whisler, KN1
Augustine, GJ; Gitler, D; Greengard, P; Phillips, PE; Seipel, AT; Venton, BJ; Wetsel, WC; Wightman, RM1
Gosnell, HB; Grueter, BA; Landreth, GE; Nekrasova, T; Olsen, CM; Schramm-Sapyta, NL; Winder, DG1
Allan, AM; Barsness, B; Martenson, T; Paz, R; Tanner, D1
Johnson, MA; Miller, CE; Rajan, V; Wightman, RM1
Carta, M; Collu, M; Fadda, F; Stancampiano, R1
Beardsley, PM; Robles, JR; van den Oord, EJ; Vargas-Irwin, C1
Borges, F; Cardoso, SM; Cunha-Oliveira, T; de Oliveira, CR; Macedo, T; Rego, AC; Swerdlow, RH1
Katz, ES; Mantsch, JR1
Chocyk, A; Czyrak, A; Wedzony, K1
Cryan, JF; Kaupmann, K; Lhuillier, L; Mombereau, C1
Andren, PE; Svenningsson, P; Zhang, X1
Achat-Mendes, C; Anderson, KL; Itzhak, Y1
Cunningham, KA; Geng, T; Kurosky, A; Luxon, BA; Seitz, PK; Soman, KV; Thomas, ML; Xu, B1
Dhaliwal, SK; Guerriero, RM; Hayes, MM; Kosofsky, BE; Ren, JQ1
Baron, DA; Raffa, RB; Rawls, SM; Rodriguez, T1
Davidson, C; Ellinwood, EH; Lazarus, C; Lee, TH; Wetsel, WC; Zhang, X1
Altar, CA; Feltenstein, MW; See, RE1
Booze, RM; Buxhoeveden, DP; Buxhoeveden, NE; Hasselrot, U; Mactutus, CF1
Antkiewicz-Michaluk, L; Filip, M; Michaluk, J; Przegaliński, E; Romańska, I; Vetulani, J1
Froimowitz, M; Gardner, EL; Giordano, A; Lepore, M; Liu, X; Paredes, W; Spector, J; Wu, KM1
Camarasa, J; Chipana, C; Escubedo, E; Pubill, D1
Barcia, JA; Canales, JJ; Domínguez-Escribà, L; García-Verdugo, JM; Hernández-Rabaza, V; Romero, FJ; Soriano-Navarro, M1
Raffa, RB; Stagliano, GW; Tallarida, RJ1
Levitt, P; Parlaman, JP; Stanwood, GD1
Hope, BT; Kreuter, JD; Mattson, BJ; Mitchell, TB; Simmons, DE1
Carroll, ME; Newman, JL1
Alvarenga, TA; Andersen, ML; Papale, LA; Tufik, S1
Ago, Y; Baba, A; Hashimoto, H; Hayashi, A; Itoh, S; Kakuda, M; Matsuda, T; Nakamura, S1
Burton, NC; Guilarte, TR; Kensler, TW1
Akhavan, A; Festa, ED; Jenab, S; Niyomchai, T; Quiñones-Jenab, V1
Cavanaugh, DJ; Kravitz, AV; Lynch, KG; Peoples, LL1
Manzardo, AM; O'Dell, LE; Parsons, LH; Polis, I; Stouffer, DG1
Fu, Y; Gallagher, JP; Genzer, K; Krishnan, B; Liu, J; Orozco-Cabal, L; Pollandt, S; Shinnick-Gallagher, P1
Fabian, S; Jenab, S; Quiñones-Jenab, V; Wu, HB1
Kalivas, PW; Melendez, RI; Murphy, TH; Pacchioni, AM; Shih, A; Vallone, J1
Black, YD; Di Pietro, NC; Kantak, KM1
Ben-Shahar, O; Brake, W; Cook, M; Ettenberg, A; Heston, R; Joyce, M; Keeley, P; Nyffeler, M1
Cryan, JF; Markou, A; Slattery, DA1
Griffin, WC; Middaugh, LD; Tyor, WR1
Calhoun, TL; Czoty, PW; Nader, MA; Nader, SH; Reboussin, BA1
Aujla, H; González-Cuevas, G; López-Moreno, JA; Martin-Fardon, R; Navarro, M; Weiss, F1
Dickinson, A; Everitt, BJ; Pelloux, Y1
Baker, DA; Francis, DM; Hoks, MA; Katz, ES; Mantsch, JR; Serge, JP1
Barnea-Ygael, N; Cooper, A; Levy, D; Shaham, Y; Zangen, A1
Elliott, JC; Feltenstein, MW; See, RE1
Calu, DJ; Franz, TM; Roesch, MR; Schoenbaum, G; Singh, T; Stalnaker, TA1
Filip, M; Frankowska, M1
Cepeda, IL; Cornfeldt, ML; Doudet, DJ; Flores, J; O'Kusky, JR1
Cho, AK; Fairbanks, LA; Jorgensen, MJ; Laćan, G; Melega, WP; Morton, G; Pham, J; Way, BM1
Hearing, MC; McGinty, JF; Schwendt, M; See, RE1
De Montis, MG; Gambarana, C; Raone, A; Scheggi, S; Tagliamonte, A1
Gass, JT; Olive, MF1
Glowinski, J; Lanteri, C; Salomon, L; Tassin, JP; Torrens, Y1
Dillon, C; Gardner, EL; Li, SJ; Li, X; Peng, XQ; Spiller, K; Xi, ZX; Yang, Z1
Cabral, H; López-Patiño, MA; Yu, L; Zhdanova, IV1
Bachtell, RK; DiLeone, RJ; Garth, WJ; Green, TA; LaPlant, Q; Nestler, EJ; Perrotti, LI; Russo, SJ; Self, DW; Theobald, DE; Winstanley, CA1
Azari, S; Wang, B; Wise, RA; You, ZB; Zitzman, D1
Boudreau, AC; Milovanovic, M; Reimers, JM; Wolf, ME1
Becker, JB; Hu, M1
Baekelandt, V; Bormans, G; Casteels, C; Lauwers, E; Van Laere, K1
De Biasi, M; Gangitano, D; Main, A; Salas, R1
Adinoff, B; Williams, MJ1
Benham-Hermetz, J; Di Ciano, P; Fogg, AP; Osborne, GE1
Ary, AW; Szumlinski, KK1
Adams, RJ; Alexander, M; Brasić, JR; Burton, NC; Chen, MK; Guilarte, TR; Kumar, A; Kuwabara, H; McGlothan, JL; Verina, T; Wong, DF; Zhou, Y1
Bassel-Duby, R; Covington, HE; Graham, A; Haggarty, SJ; Kerstetter, KA; Kippin, TE; Krishnan, V; Kumar, A; Maze, I; McKinsey, TA; Nestler, EJ; Neve, RL; Olson, EN; Renthal, W; Russo, SJ; Tsankova, N; Xiao, G1
Hnasko, TS; Palmiter, RD; Sotak, BN1
Giros, B; Herzog, CJ; Mansuy, IM; Miot, S; Tzavara, ET1
George, O; Koob, GF; Mandyam, CD; Wee, S1
Kane, GC; Miki, T; Reyes, S; Seino, S; Terzic, A1
McElligott, ZA; Winder, DG1
Akhavan, A; Festa, ED; Jenab, S; Luine, V; Minerly, AC; Nazarian, A; Niyomchai, T; Quiñones-Jenab, V; Russo, SJ; Sun, WL; Weierstall, K1
Cleveland, N; Dart, RC; DeWitt, CR; Heard, K1
Del Valle, LJ; Mercedes, A; Orihuela, PA; Pella, R; Velasquez, LA1
Liles, LC; Schank, JR; Weinshenker, D1
Ding, Z; Phillips, AG; Powell, JA; Raffa, RB; Rawls, SM; Ross, G; Stagliano, GW1
Ago, Y; Baba, A; Matsuda, T; Nakamura, S1
Hoffman, RS; Manini, AF; Pearl-Davis, MS; Wu, S1
Ben-Shahar, O; Ettenberg, A; Posthumus, EJ; Waldroup, SA1
Akbarian, S; Jones, SR; Konradi, C; Matevossian, A; Penta, KL; Schroeder, FA; Tapper, AR1
Akil, H; Briand, LA; Flagel, SB; Garcia-Fuster, MJ; Robinson, TE; Sarter, M; Watson, SJ1
Berger, M; Hornyak, M; Riemann, D; Schierenbeck, T1
Crespo, JA; Saria, A; Stöckl, P; Zernig, G; Zorn, K1
Andren, PE; Chergui, K; Svenningsson, P; Zhang, X1
Dow-Edwards, D; Wang, HY; Zhao, N1
Kalivas, PW; Tang, XC; Torregrossa, MM1
Guan, X; Hu, J; Li, S1
Carroll, ME; Nelson, SE; Perry, JL1
Singer, G; Wallace, M1
Khodzhagel'diev, T1
MacLennan, AJ; Maier, SF1
Koob, GF; Weiss, F; Weissenborn, R; Yackey, M1
Drieze, J; Lukas, SE; Mello, NK; Mendelson, JH; Negus, SS; Sholar, JW1
Groce, MY; Hammer, JG; Harvey, JA; Jones, L; Murphy, EH; Romano, AG; Schumann, MD; Wang, XH1
Daunais, JB; McGinty, JF1
LeDuc, PA; Mittleman, G1
Evrard, P; Gressens, P; Kosofsky, BE; Wilkins, AS1
Carroll, ME; Lac, ST; Specker, SM1
Janssen, PA1
Altuğ, T; Büyükünal, C; Dervişoğlu, S; Kiliç, N1
Lopez, MC; Watson, RR1
Alak, J; Darban, H; Thomas, N; Watson, RR1
Cappendijk, SL; Dzoljic, MR1
Ellison, G; Switzer, RC1
Erwin, VG; Jones, BC; Morse, AC1
Dworkin, SI; Pitts, RC1
Carroll, ME1
Pert, A1
Kuhar, MJ; Pilotte, NS1
Carolino, RM; Patacao, MH; Silva-Araújo, A; Tavares, MA1
Ando, K; Fujita, T; Shimosawa, T1
Jurado, C; Menéndez, M; Repetto, M; Rodriguez-Vicente, C1
Yamamoto, J1
Knapp, FF; Oster, ZH; Sacker, DF; Som, P; Volkow, ND; Wang, GJ1
Guix, T; Hurd, YL; McGregor, A; Pontén, M; Ungerstedt, U1
Caron, MG; Giros, B; Jaber, M; Jones, S1
Evrard, P1
Fox, BS1
Gorelick, DA1
Laferrière, A; Moss, IR1
Antelman, SM; Austin, MC; Caggiula, AR; Edwards, DJ; Fowler, H; Gershon, S; Kiss, S; Kocan, D; Kucinski, BJ; Stiller, R1
Dalia, AD; Norman, AB; Norman, MK; Schlueter, KT; Tabet, MR; Tsibulsky, VL1
Areso, MP; García-Vallejo, P; Giralt, MT; Gómez, FM; Sainz, B1
Kosofsky, BE; Wilkins, AS1
Jaber, M1
Almonte, R; Briscoe, RJ; Cabrera, C; Jamdar, S; Landry, DW; Mets, B; Seo, S; Winger, G; Woods, JH; Yang, G; Zhao, K1
Borowski, TB; Kokkinidis, L1
Fujita, M; Ito, Y; Kusuoka, H; Nishimura, T; Okada, T; Shimada, S; Tohyama, M; Watanabe, Y1
Kosofsky, BE; Malanga, CJ1
Dempsey, DA; Ferriero, DM1
Arroyo, M; Everitt, BJ; Markou, A1
Brownell, AL; Isacson, O; Jenkins, BG1
Burton, FH; Campbell, KM; McGrath, MJ1
Chen, JP; Gardner, E; Hen, R; Scearce-Levie, K1
Gasior, M; Ungard, JT; Witkin, JM1
Akoka, S; Arbeille, B; Arbeille, P; Gemberg, C; Lansac, J; Laurini, RN; Locatelli, A1
Wolf, ME1
Carroll, ME; Lynch, WJ1
Grimm, JW; See, RE1
Grimm, JW; Kruzich, PJ; Parks, CD; Rustay, NR; See, RE1
Stoessl, AJ; Van Kampen, JM1
Jennings, RE; Malin, DH; Moon, WD; Moy, DM; Moy, ET; Warner, RL; Wilson, OB1
Le Foll, B; Schwartz, JC; Sokoloff, P1
Abiru, H; Fukui, Y; Hayase, T; Nishitani, Y; Yamamoto, K; Yamamoto, Y1
Cornish, JL; Kalivas, PW1
Barrett-Larimore, RL; Khroyan, TV; Rowlett, JK; Spealman, RD1
Araujo, DM; Cherry, SR; Kornblum, HI; Tatsukawa, KJ; Toyokuni, T1
Hemby, SE1
Cossu, G; Fattore, L; Fratta, W; Martellotta, MC; Mascia, MS1
Glowa, JR; Lewis, DB; Rice, KC; Stafford, D1
Cazala, P; David, V; Gold, LH; Koob, GF1
Berrettini, WH; Ferraro, TN; Golden, GT; Jones, NL; Smith, GG; Snyder, RL1
Partridge, B; Schenk, S; Shippenberg, TS1
Dorbandt, A; Garvey, L; Jeromin, J; Wilson, LD1
Dewey, SL; Mackler, SA; O'Brien, CP; Stromberg, MF; Volpicelli, JR1
Bédard, PJ; Blanchet, PJ; Calon, F; Di Paolo, T; Goulet, M; Grondin, R; Lavertu, N; Lemieux, AM; Morissette, M1
Friedman, DP; Letchworth, SR; Nader, MA; Porrino, LJ; Smith, HR1
Bohn, MC; Connor, B; Elsworth, JD; Kozlowski, DA; Schallert, T; Tillerson, JL; Unnerstall, JR1
Hyman, SE; Kosofsky, BE1
Angeletti, S; Ben-Shahar, O; Ciccocioppo, R; Katner, S; Liu, X; Parsons, LH; Richter, RR; Valdez, GR; Weiss, F; Zorrilla, EP1
Kulak, JM; McIntosh, JM; Polonskaya, Y; Quik, M1
Leri, F; Stewart, J1
Piomelli, D1
Crombag, H; De Vries, TJ; Dieben, J; Homberg, JR; Schoffelmeer, AN; Schuurman, K; Shaham, Y; Vanderschuren, LJ1
Kalivas, PW; McFarland, K1
Raffa, RB; Valdez, JM1
Blendy, JA; Walters, CL1
Abelmann, WH; Crumpacker, CS; Min, JY; Morgan, JP; Sullivan, MF; Wang, JF; Zhang, J1
Barroso-Moguel, R; Mendez-Armenta, M; Nava-Ruiz, C; Santamaria, A; Villeda-Hernandez, J1
Baldwin, GC; Choi, R; Jamieson, BD; Roth, MD; Tashkin, DP; Zack, JA1
Li, Y; Robinson, TE; Samaha, AN1
Artru, A; Bernards, CM; Lam, A; Powers, KM; Visco, E1
Black, Y; Eichenbaum, HB; Green-Jordan, K; Kantak, KM; Valencia, E1
Ahmed, SH; Kenny, PJ; Koob, GF; Markou, A1
Beinfeld, MC; Connolly, KJ; Pierce, RC1
Hickey, MA; Morton, AJ; Reynolds, GP1
Katz, JL; Mead, AN; Rocha, BA1
Ali, SF; Alper, K; Binienda, ZK; Pereira, F; Slikker, W1
Spealman, RD1
Flemenbaum, A1
Castellani, S; Ellinwood, EH; Kilbey, MM1
Brewster, JM; Jarvik, ME; Johnson, CA; Siegel, RK1
Martinez, F; Poet, TS; Watson, RR1
Colombo, LL; Huang, DS; Lopez, MC; Watson, RR1
Koob, GF; Markou, A2
Balster, RL; Gold, L; Harris, LS; Mansbach, RS1
Meyer, RE1
Brownell, AL; Brownell, GL; Elmaleh, D; Hantraye, P; Isacson, O; Madras, BK; Spealman, RD; Wüllner, U1
Dow-Edwards, D; Hutchings, DE1
Chen, GJ; Watson, RR1
Chan, MK; Gingras, JL; Klemka-Walden, LM; Weese-Mayer, DE1
Ellison, G; Lipton, J; Wilkins, J; Zeigler, S1
Carney, JM; Cheng, MS; Landrum, RW; Seale, TW1
Chen, GJ; Huang, DS; Lopez, MC; Watson, RR; Watzl, B1
Ho, IK; Hoskins, B; Oh, SK; Rockhold, RW; Tseng, YT1
Gingras, JL; Weese-Mayer, D1
Ettenberg, A; Geist, TD1
Carroll, ME; Gieske, D; Krattiger, KL; Sadoff, DA1
Cassidy, W; Kanel, GC; Reynolds, TB; Shuster, L1
Jaffe, JH; Sharpe, LG; Weinhold, LL1
Post, RM; Weiss, SR1
Costall, B; Kelly, ME; Naylor, RJ; Onaivi, ES1
Marquis, KL; Moreton, JE1
Amit, Z; Gorman, K; Lacelle, G; Schenk, S1
Snyder, SH1
Fog, R1
Areal, LB; Herlinger, AL; Martins-Silva, C; Pelição, FS; Pires, RGW1
de Melo Rodrigues, LC; E Silva, CM; Gomes, EF; Lipaus, IFS; Malgarin, F; Martins, CW; Palacios, EMN; Pires, RGW; Schuck, PF1
Aliyeva, M; Ather, JL; Casey, DT; Chapman, DG; Daphtary, N; Irvin, CG; Janssen-Heininger, YMW; Lahue, KG; van der Velden, JL1
Latif, R1
Abe, S; Ezawa, K; Hayama, K; Kishi, A; Matsukawa, T; Sato, N; Suzuki, M; Takahashi, M; Yamazaki, M1
Arribas, B; Bailon, E; Buttersack, C; Gálvez, J; García Fernández, JM; Garrido-Mesa, N; Guerra-Hernández, E; Ortiz Mellet, C; Rodríguez-Cabezas, ME; Suárez-Pereira, E; Zarzuelo, A1
Bibby, BG1

Reviews

73 review(s) available for cocaine and Disease Models, Animal

ArticleYear
Adenosine A
    Cells, 2020, 06-01, Volume: 9, Issue:6

    Topics: Animals; Behavior; Brain; Cocaine; Disease Models, Animal; Humans; Receptor, Adenosine A2A; Substance-Related Disorders

2020
Mini review: Promotion of substance abuse in HIV patients: Biological mediation by HIV-1 Tat protein.
    Neuroscience letters, 2021, 05-14, Volume: 753

    Topics: Analgesics, Opioid; Animals; Brain; Cocaine; Disease Models, Animal; Ethanol; HIV Infections; HIV-1; Humans; Mice; Quality of Life; Reward; Substance-Related Disorders; tat Gene Products, Human Immunodeficiency Virus

2021
Modulation of drug choice by extended drug access and withdrawal in rhesus monkeys: Implications for negative reinforcement as a driver of addiction and target for medications development.
    Pharmacology, biochemistry, and behavior, 2018, Volume: 164

    Topics: Animals; Choice Behavior; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Food; Heroin; Heroin Dependence; Humans; Macaca mulatta; Narcotic Antagonists; Opioid-Related Disorders; Reinforcement, Psychology; Substance Withdrawal Syndrome

2018
Planaria: an animal model that integrates development, regeneration and pharmacology.
    The International journal of developmental biology, 2017, Volume: 61, Issue:8-9

    Topics: Animals; Behavior, Animal; Cocaine; Developmental Biology; Disease Models, Animal; Dopamine Uptake Inhibitors; Planarians; Regeneration

2017
Modeling cocaine relapse in rodents: Behavioral considerations and circuit mechanisms.
    Progress in neuro-psychopharmacology & biological psychiatry, 2018, 12-20, Volume: 87, Issue:Pt A

    Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Drug-Seeking Behavior; Extinction, Psychological; Humans; Neural Pathways; Recurrence; Rodentia; Self Administration

2018
Addictive behaviour in experimental animals: prospects for translation.
    Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2018, 03-19, Volume: 373, Issue:1742

    Topics: Animals; Behavior, Addictive; Cocaine; Conditioning, Operant; Cues; Disease Models, Animal; Humans; Memory; Mice; Pharmaceutical Preparations; Primates; Rats; Reinforcement, Psychology; Reward; Translational Research, Biomedical

2018
Social modulation of drug use and drug addiction.
    Neuropharmacology, 2019, 11-15, Volume: 159

    Topics: Analgesics, Opioid; Animals; Cocaine; Conditioning, Operant; Disease Models, Animal; Drug-Seeking Behavior; Humans; Self Administration; Social Behavior; Substance-Related Disorders

2019
Central GLP-1 receptors: Novel molecular targets for cocaine use disorder.
    Physiology & behavior, 2019, 07-01, Volume: 206

    Topics: Animals; Behavior, Addictive; Brain; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Glucagon-Like Peptide-1 Receptor; Humans; Reward; Self Administration

2019
Bipolar disorder and substance misuse: pathological and therapeutic implications of their comorbidity and cross-sensitisation.
    The British journal of psychiatry : the journal of mental science, 2013, Volume: 202, Issue:3

    Topics: Acetylcysteine; Age of Onset; Animals; Basal Ganglia; Behavior, Addictive; Bipolar Disorder; Brain-Derived Neurotrophic Factor; Central Nervous System Sensitization; Cocaine; Cocaine-Related Disorders; Comorbidity; Diagnosis, Dual (Psychiatry); Disease Models, Animal; Disease Progression; Dopamine Uptake Inhibitors; Epigenomics; Free Radical Scavengers; Humans; Recurrence; Stress, Psychological

2013
PET studies in nonhuman primate models of cocaine abuse: translational research related to vulnerability and neuroadaptations.
    Neuropharmacology, 2014, Volume: 84

    Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Cognition; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Humans; Positron-Emission Tomography; Primates; Sex Characteristics

2014
Rats classified as low or high cocaine locomotor responders: a unique model involving striatal dopamine transporters that predicts cocaine addiction-like behaviors.
    Neuroscience and biobehavioral reviews, 2013, Volume: 37, Issue:8

    Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Motor Activity; Rats

2013
William L. Woolverton: a case history in unraveling the behavioral pharmacology of stimulants.
    Neuropharmacology, 2014, Volume: 87

    Topics: Animals; Central Nervous System Stimulants; Choice Behavior; Cocaine; Disease Models, Animal; Dopamine; History, 20th Century; History, 21st Century; Neuropharmacology; Self Administration; Substance-Related Disorders

2014
Effects of prenatal exposure to cocaine on brain structure and function.
    Progress in brain research, 2014, Volume: 211

    Topics: Animals; Brain; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Female; Mice; Neurogenesis; Pregnancy; Prenatal Exposure Delayed Effects

2014
The Gateway Hypothesis of substance abuse: developmental, biological and societal perspectives.
    Acta paediatrica (Oslo, Norway : 1992), 2015, Volume: 104, Issue:2

    Topics: Animals; Behavior, Animal; Cocaine; Corpus Striatum; Disease Models, Animal; Disease Progression; Dopamine Uptake Inhibitors; Ganglionic Stimulants; Humans; Nicotine; Substance-Related Disorders

2015
Multiple faces of BDNF in cocaine addiction.
    Behavioural brain research, 2015, Feb-15, Volume: 279

    Topics: Animals; Brain; Brain-Derived Neurotrophic Factor; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Corpus Striatum; Craving; Disease Models, Animal; Mice; Neuronal Plasticity; Rats; Receptors, AMPA; Reward; Self Administration

2015
Serotonin 5-HT2 receptor interactions with dopamine function: implications for therapeutics in cocaine use disorder.
    Pharmacological reviews, 2015, Volume: 67, Issue:1

    Topics: Animals; Behavior, Addictive; Behavior, Animal; Brain; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine; Drug Design; Humans; Molecular Targeted Therapy; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Serotonin Agents; Synaptic Transmission

2015
Cortical consequences of HIV-1 Tat exposure in rats are enhanced by chronic cocaine.
    Current HIV research, 2015, Volume: 13, Issue:1

    Topics: Animals; Brain; Cerebral Cortex; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; HIV Infections; HIV-1; Neurocognitive Disorders; Rats; tat Gene Products, Human Immunodeficiency Virus

2015
Effects of drugs of abuse on the central neuropeptide Y system.
    Addiction biology, 2016, Volume: 21, Issue:4

    Topics: Amphetamines; Animals; Brain; Cocaine; Disease Models, Animal; Ethanol; Mice; Neuropeptide Y; Nicotine; Opiate Alkaloids; Rats; Receptors, Neuropeptide Y

2016
[Depression and addiction comorbidity: towards a common molecular target?].
    Medecine sciences : M/S, 2015, Volume: 31, Issue:5

    Topics: Anhedonia; Animals; Annexin A2; Appetitive Behavior; Cholinergic Neurons; Cocaine; Comorbidity; Depression; Depressive Disorder; Disease Models, Animal; Genetic Therapy; Genetic Vectors; Humans; Interneurons; Mice; Mice, Knockout; Molecular Targeted Therapy; Nerve Tissue Proteins; Neural Pathways; Neurotransmitter Agents; Nucleus Accumbens; Optogenetics; Pleasure; Prevalence; Protein Transport; Receptors, Neurotransmitter; Reward; RNA Interference; S100 Proteins; Substance-Related Disorders

2015
Evidence-based recommendations on the use of intravenous lipid emulsion therapy in poisoning
    Clinical toxicology (Philadelphia, Pa.), 2016, Volume: 54, Issue:10

    Topics: Administration, Intravenous; Anesthetics; Animals; Calcium Channel Blockers; Cocaine; Diphenhydramine; Disease Models, Animal; Evidence-Based Medicine; Fat Emulsions, Intravenous; Humans; Lamotrigine; Poisoning; Randomized Controlled Trials as Topic; Triazines

2016
Drosophila, a genetic model system to study cocaine-related behaviors: a review with focus on LIM-only proteins.
    Neuropharmacology, 2009, Volume: 56 Suppl 1

    Topics: Animals; Animals, Genetically Modified; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Drosophila melanogaster; Drosophila Proteins; Homeodomain Proteins; Models, Genetic

2009
Prospects for serotonin 5-HT2R pharmacotherapy in psychostimulant abuse.
    Progress in brain research, 2008, Volume: 172

    Topics: Animals; Behavior, Animal; Brain; Central Nervous System Stimulants; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Humans; Motor Activity; Neural Pathways; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Substance-Related Disorders; Synaptic Transmission

2008
Cortical and sub-cortical effects in primate models of cocaine use: implications for addiction and the increased risk of psychiatric illness.
    Neurotoxicity research, 2011, Volume: 19, Issue:2

    Topics: Animals; Behavior, Addictive; Cerebral Cortex; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine; Humans; Risk Factors; Self Administration

2011
Transgenic mice in the study of drug addiction and the effects of psychostimulant drugs.
    Annals of the New York Academy of Sciences, 2010, Volume: 1187

    Topics: Amphetamine-Related Disorders; Amphetamines; Animals; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Mice; Mice, Knockout; Mice, Transgenic; Neurotransmitter Transport Proteins; Phenotype; Substance-Related Disorders

2010
The role of progestins in the behavioral effects of cocaine and other drugs of abuse: human and animal research.
    Neuroscience and biobehavioral reviews, 2010, Volume: 35, Issue:2

    Topics: Animals; Behavior, Addictive; Cocaine; Disease Models, Animal; Drug-Seeking Behavior; Humans; Illicit Drugs; Progestins; Substance-Related Disorders

2010
Validation crisis in animal models of drug addiction: beyond non-disordered drug use toward drug addiction.
    Neuroscience and biobehavioral reviews, 2010, Volume: 35, Issue:2

    Topics: Animals; Choice Behavior; Cocaine; Disease Models, Animal; Humans; Self Administration; Substance-Related Disorders; Validation Studies as Topic

2010
Behavioral evidence for the significance of serotoninergic (5-HT) receptors in cocaine addiction.
    Addiction biology, 2010, Volume: 15, Issue:3

    Topics: Animals; Appetitive Behavior; Association Learning; Brain; Cocaine; Cocaine-Related Disorders; Conditioning, Classical; Consummatory Behavior; Discrimination, Psychological; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Emotions; Euphoria; Humans; Motivation; Norepinephrine Plasma Membrane Transport Proteins; Rats; Receptors, Serotonin; Self Administration; Substance Withdrawal Syndrome

2010
Benzodiazepines and antipsychotic medications for treatment of acute cocaine toxicity in animal models--a systematic review and meta-analysis.
    Human & experimental toxicology, 2011, Volume: 30, Issue:11

    Topics: Animals; Antipsychotic Agents; Benzodiazepines; Cocaine; Disease Models, Animal

2011
The science of making drug-addicted animals.
    Neuroscience, 2012, Jun-01, Volume: 211

    Topics: Animals; Behavior, Animal; Cocaine; Disease Models, Animal; Drug Discovery; Self Administration; Substance-Related Disorders

2012
Drosophila melanogaster as a model to study drug addiction.
    Human genetics, 2012, Volume: 131, Issue:6

    Topics: Amphetamines; Animals; Behavior, Animal; Cocaine; Disease Models, Animal; Drosophila melanogaster; Ethanol; Neural Pathways; Nicotine; Substance-Related Disorders; Synaptic Transmission

2012
Rodent models of HAND and drug abuse: exogenous administration of viral protein(s) and cocaine.
    Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 2012, Volume: 7, Issue:2

    Topics: AIDS Dementia Complex; Animals; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Disease Models, Animal; Humans; Immunohistochemistry; Injections, Intraventricular; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurotoxins; Rats; Rats, Sprague-Dawley; tat Gene Products, Human Immunodeficiency Virus

2012
Medication discovery for addiction: translating the dopamine D3 receptor hypothesis.
    Biochemical pharmacology, 2012, Oct-01, Volume: 84, Issue:7

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Humans; Methamphetamine; Molecular Structure; Receptors, Dopamine D3; Substance-Related Disorders

2012
Nonhuman primate models of social behavior and cocaine abuse.
    Psychopharmacology, 2012, Volume: 224, Issue:1

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Female; Housing, Animal; Humans; Macaca fascicularis; Male; Models, Animal; Primates; Self Administration; Sex Factors; Social Behavior; Species Specificity; Stress, Psychological

2012
Responses to novelty and vulnerability to cocaine addiction: contribution of a multi-symptomatic animal model.
    Cold Spring Harbor perspectives in medicine, 2012, Nov-01, Volume: 2, Issue:11

    Topics: Animals; Behavior, Addictive; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Exploratory Behavior; Humans; Impulsive Behavior; Personality; Psychopathology

2012
The role of setting for ketamine abuse: clinical and preclinical evidence.
    Reviews in the neurosciences, 2012, Volume: 23, Issue:5-6

    Topics: Animals; Clinical Trials as Topic; Cocaine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Ketamine; Rats; Substance-Related Disorders

2012
[Genetic study on schizophrenia and its recurrence utilizing pharmacological models].
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 2002, Volume: 104, Issue:6

    Topics: Amphetamine; Animals; Central Nervous System Stimulants; Cocaine; Disease Models, Animal; Dopamine Agents; Humans; Ketamine; Phencyclidine; Receptors, N-Methyl-D-Aspartate; Recurrence; Schizophrenia

2002
Invertebrate models of drug abuse.
    Journal of neurobiology, 2003, Volume: 54, Issue:1

    Topics: Alcoholic Intoxication; Animals; Behavior, Animal; Caenorhabditis elegans; Cocaine; Disease Models, Animal; Dopamine; Drosophila melanogaster; Drug Tolerance; Ethanol; Learning; Memory; Nicotine; Substance-Related Disorders

2003
Drug addiction.
    The New England journal of medicine, 2003, Sep-04, Volume: 349, Issue:10

    Topics: Animals; Cannabinoids; Cocaine; Disease Models, Animal; Dopamine; Ethanol; Humans; Narcotics; Nicotine; Recurrence; Reinforcement, Psychology; Substance Withdrawal Syndrome; Substance-Related Disorders

2003
Sensitization to the reinforcing effects of cocaine following binge-abstinent self-administration.
    Neuroscience and biobehavioral reviews, 2004, Volume: 27, Issue:8

    Topics: Animals; Behavior, Addictive; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Humans; Motor Activity; Narcotics; Reinforcement Schedule; Reinforcement, Psychology; Self Administration

2004
Neurobiology of seizures and behavioral abnormalities.
    Epilepsia, 2004, Volume: 45 Suppl 2

    Topics: Amygdala; Animals; Anticonvulsants; Behavior, Animal; Bipolar Disorder; Brain; Cats; Cocaine; Disease Models, Animal; Drug Tolerance; Humans; Kindling, Neurologic; Mental Disorders; Rats; Seizures

2004
Drug-induced neurobehavioral plasticity: the role of environmental context.
    Behavioural pharmacology, 2004, Volume: 15, Issue:5-6

    Topics: Amphetamine; Animals; Behavior; Brain; Central Nervous System Stimulants; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Environment; Exploratory Behavior; Gene Expression Regulation; Humans; Morphine; Narcotics; Neuronal Plasticity; Substance-Related Disorders

2004
Gonadal hormones provide the biological basis for sex differences in behavioral responses to cocaine.
    Hormones and behavior, 2004, Volume: 46, Issue:5

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Estrous Cycle; Female; Gonadal Steroid Hormones; Humans; Male; Mice; Orchiectomy; Ovariectomy; Rats; Sex Characteristics

2004
[Behavioral and pharmacological characteristics of mice lacking the dopamine transporter].
    Postepy higieny i medycyny doswiadczalnej (Online), 2004, Volume: 58

    Topics: Adaptation, Physiological; Amphetamines; Animals; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Cocaine; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Humans; Hyperkinesis; Mice; Mice, Knockout; Morphine; Narcotics

2004
Bacteriophage-mediated protein delivery into the central nervous system and its application in immunopharmacotherapy.
    Expert opinion on biological therapy, 2005, Volume: 5, Issue:6

    Topics: Administration, Intranasal; Animals; Antibodies; Central Nervous System; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Drug Delivery Systems; Inovirus; Proteins; Rats

2005
Glutamatergic substrates of drug addiction and alcoholism.
    Biochemical pharmacology, 2008, Jan-01, Volume: 75, Issue:1

    Topics: Alcoholism; Amphetamines; Animals; Cannabinoids; Cocaine; Disease Models, Animal; Extinction, Psychological; Glutamic Acid; Humans; Narcotics; Neuronal Plasticity; Nicotine; Substance-Related Disorders; Synapses; Synaptic Transmission

2008
The effects of cocaine: a shifting target over the course of addiction.
    Progress in neuro-psychopharmacology & biological psychiatry, 2007, Nov-15, Volume: 31, Issue:8

    Topics: Animals; Brain; Brain Chemistry; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Humans; Substance Withdrawal Syndrome

2007
Sex differences in drug abuse.
    Frontiers in neuroendocrinology, 2008, Volume: 29, Issue:1

    Topics: Animals; Cocaine; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Estradiol; Estrogen Receptor alpha; Estrous Cycle; Ethanol; Female; Humans; Male; Models, Biological; Narcotics; Nicotine; Psychomotor Performance; Risk Factors; Sex Characteristics; Sex Chromosomes; Substance-Related Disorders

2008
The role of acetylcholine in cocaine addiction.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008, Volume: 33, Issue:8

    Topics: Acetylcholine; Adaptation, Psychological; Animals; Cocaine; Cocaine-Related Disorders; Cognition; Disease Models, Animal; Humans; Learning; Memory; Neostriatum; Parasympathetic Nervous System; Reward

2008
Neuropsychotoxicity of abused drugs: effects of serotonin receptor ligands on methamphetamine- and cocaine-induced behavioral sensitization in mice.
    Journal of pharmacological sciences, 2008, Volume: 106, Issue:1

    Topics: Amphetamine-Related Disorders; Animals; Behavior, Animal; Brain; Bridged Bicyclo Compounds, Heterocyclic; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Dioxanes; Dioxoles; Disease Models, Animal; Ligands; Methamphetamine; Mice; Motor Activity; Oxazines; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin 5-HT3 Receptor Antagonists; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists

2008
Effect of illicit recreational drugs upon sleep: cocaine, ecstasy and marijuana.
    Sleep medicine reviews, 2008, Volume: 12, Issue:5

    Topics: Animals; Brain; Cocaine; Disease Models, Animal; Dronabinol; Humans; Illicit Drugs; N-Methyl-3,4-methylenedioxyamphetamine; Polysomnography; Sleep; Sleep Stages; Substance Withdrawal Syndrome; Substance-Related Disorders

2008
Addiction and the potential for therapeutic drug development.
    EXS, 1994, Volume: 71

    Topics: Alcoholism; Animals; Cocaine; Disease Models, Animal; Double-Blind Method; Humans; Research Design; Ritanserin; Substance-Related Disorders

1994
Pharmacogenetics of cocaine: a critical review.
    Pharmacogenetics, 1995, Volume: 5, Issue:4

    Topics: Animals; Body Temperature Regulation; Brain; Cocaine; Disease Models, Animal; Dopamine; Exploratory Behavior; Heart Rate; Humans; Liver; Mice; Mice, Inbred Strains; Motor Activity; Rats; Rats, Inbred Strains; Seizures; Serotonin; Species Specificity; Substance-Related Disorders

1995
Use of rodent self-administration models to develop pharmacotherapies for cocaine abuse.
    NIDA research monograph, 1994, Volume: 145

    Topics: Animals; Cocaine; Disease Models, Animal; Drug Design; Rodentia; Self Administration; Substance-Related Disorders; Tropanes

1994
Pharmacological and behavioral treatment of cocaine addiction: animal models.
    NIDA research monograph, 1994, Volume: 145

    Topics: Animals; Catheters, Indwelling; Cocaine; Disease Models, Animal; Macaca mulatta; Rats; Reinforcement, Psychology; Self Administration; Smoking; Substance-Related Disorders

1994
Neurobiological mechanisms underlying the acquisition and expression of incentive motivation by cocaine-associated stimuli: relationship to craving.
    NIDA research monograph, 1994, Volume: 145

    Topics: Animals; Cocaine; Conditioning, Operant; Disease Models, Animal; Feeding Behavior; Humans; Motivation; Motor Activity; Neurobiology; Substance Withdrawal Syndrome; Substance-Related Disorders

1994
Neurochemical changes in cocaine withdrawal.
    Trends in pharmacological sciences, 1996, Volume: 17, Issue:7

    Topics: Animals; Brain Chemistry; Cocaine; Disease Models, Animal; Dopamine; Drug Design; Frontal Lobe; Humans; Image Processing, Computer-Assisted; Neurons; Nucleus Accumbens; Substance Withdrawal Syndrome; Synapses

1996
The dopamine transporter: a crucial component regulating dopamine transmission.
    Movement disorders : official journal of the Movement Disorder Society, 1997, Volume: 12, Issue:5

    Topics: Amphetamines; Animals; Brain; Carrier Proteins; Central Nervous System Stimulants; Cocaine; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Gene Dosage; Genotype; Homeostasis; Humans; Hyperkinesis; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Knockout; Mice, Transgenic; Nerve Tissue Proteins; Parkinson Disease; Phenotype; Rats; Schizophrenia; Substance-Related Disorders

1997
Genetic and environmental determinants of neocortical development.
    Pediatric pulmonology. Supplement, 1997, Volume: 16

    Topics: Animals; Animals, Newborn; Cerebral Cortex; Cocaine; Disease Models, Animal; Embryonic and Fetal Development; Environmental Exposure; Ethanol; Female; Genetic Code; Mice; Neurons; Pregnancy; Prenatal Exposure Delayed Effects

1997
Enhancing cocaine metabolism with butyrylcholinesterase as a treatment strategy.
    Drug and alcohol dependence, 1997, Dec-15, Volume: 48, Issue:3

    Topics: Animals; Butyrylcholinesterase; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Enzyme Inhibitors; Humans; Macaca mulatta; Mice; Rats

1997
[Dopamine control of neuroendocrine functions. New findings based on the study of transgenic animals].
    Annales d'endocrinologie, 1997, Volume: 58, Issue:6

    Topics: Amphetamines; Animals; Carrier Proteins; Central Nervous System Stimulants; Cocaine; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Locomotion; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Knockout; Mice, Transgenic; Nerve Tissue Proteins; Neurosecretory Systems

1997
Mechanisms of action of drugs of abuse on the developing fetal brain.
    Clinics in perinatology, 1999, Volume: 26, Issue:1

    Topics: Alcoholism; Animals; Brain; Child; Child Development; Child Rearing; Cocaine; Cocaine-Related Disorders; Confounding Factors, Epidemiologic; Disease Models, Animal; Ethanol; Female; Fetus; Humans; Illicit Drugs; Narcotics; Nutritional Physiological Phenomena; Opioid-Related Disorders; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Reinforcement, Psychology; Reward; Substance-Related Disorders

1999
Impact of addictive and harmful substances on fetal brain development.
    Current opinion in neurology, 1999, Volume: 12, Issue:2

    Topics: Animals; Brain; Central Nervous System Depressants; Central Nervous System Stimulants; Cocaine; Developmental Disabilities; Disease Models, Animal; Embryonic and Fetal Development; Ethanol; Female; Humans; Nervous System Diseases; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Smoking; Species Specificity; Substance-Related Disorders

1999
Cocaine addiction: clues from Drosophila on drugs.
    Current biology : CB, 1999, Oct-21, Volume: 9, Issue:20

    Topics: Animals; Behavior, Animal; Catecholamines; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Drosophila; Humans

1999
Recent advances in the biology of addiction.
    Current psychiatry reports, 1999, Volume: 1, Issue:2

    Topics: Animals; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Humans; Rats; Receptors, Dopamine; Reinforcement, Psychology; Substance-Related Disorders

1999
No time for complacency: the fetal brain on drugs.
    The Journal of comparative neurology, 2001, Jul-02, Volume: 435, Issue:3

    Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Female; Humans; Nervous System Malformations; Pregnancy; Prenatal Exposure Delayed Effects; Substance Abuse Treatment Centers

2001
Compulsive drug-seeking behavior and relapse. Neuroadaptation, stress, and conditioning factors.
    Annals of the New York Academy of Sciences, 2001, Volume: 937

    Topics: Adaptation, Physiological; Affect; Animals; Central Nervous System Depressants; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Disease Models, Animal; Dopamine Uptake Inhibitors; Ethanol; Humans; Nucleus Accumbens; Receptors, Dopamine; Receptors, Serotonin; Recurrence; Reinforcement, Psychology; Stress, Psychological; Substance Withdrawal Syndrome; Substance-Related Disorders

2001
New pharmacotherapies for cocaine dependence ... revisited.
    Archives of general psychiatry, 1992, Volume: 49, Issue:11

    Topics: Alcoholism; Cocaine; Desipramine; Disease Models, Animal; Double-Blind Method; Heroin Dependence; Humans; Methadone; Randomized Controlled Trials as Topic; Substance-Related Disorders

1992
Animal models of opiate, cocaine, and cannabis use.
    Clinics in perinatology, 1991, Volume: 18, Issue:1

    Topics: Animals; Cannabis; Cocaine; Disease Models, Animal; Dronabinol; Female; Fetus; Maternal-Fetal Exchange; Narcotics; Pregnancy; Substance-Related Disorders

1991
Sensitization, kindling, and anticonvulsants in mania.
    The Journal of clinical psychiatry, 1989, Volume: 50 Suppl

    Topics: Animals; Anticonvulsants; Behavior, Animal; Bipolar Disorder; Cocaine; Disease Models, Animal; Humans; Kindling, Neurologic; Mice; Motor Activity; Rats; Stereotyped Behavior

1989
Catecholamines in the brain as mediators of amphetamine psychosis.
    Archives of general psychiatry, 1972, Volume: 27, Issue:2

    Topics: Amphetamine; Animals; Antidepressive Agents; Brain Chemistry; Bromides; Catecholamines; Cats; Cocaine; Compulsive Behavior; Dihydroxyphenylalanine; Disease Models, Animal; Dopamine; Hallucinogens; Humans; Isomerism; Monoamine Oxidase Inhibitors; Norepinephrine; Pan troglodytes; Paranoid Disorders; Phenothiazines; Psychoses, Alcoholic; Psychoses, Substance-Induced; Rats; Receptors, Drug; Schizophrenia; Substance-Related Disorders; Synaptic Transmission

1972
On stereotypy and catalepsy: studies on the effect of amphetamines and neuroleptics in rats.
    Acta neurologica Scandinavica. Supplementum, 1972, Volume: 50

    Topics: Amphetamine; Animals; Basal Ganglia; Caffeine; Catalepsy; Cocaine; Compulsive Behavior; Corpus Striatum; Disease Models, Animal; Dopamine; Hippocampus; Humans; Lysergic Acid Diethylamide; Methamphetamine; Methylphenidate; Morphine; Norepinephrine; Pemoline; Phenmetrazine; Psychoses, Substance-Induced; Rats; Reserpine; Thalamus; Tranquilizing Agents

1972
Health benefits of cocoa.
    Current opinion in clinical nutrition and metabolic care, 2013, Volume: 16, Issue:6

    Topics: Animals; Antioxidants; Cacao; Candy; Cognition; Disease Models, Animal; Flavonoids; Food Hypersensitivity; Glucose Transporter Type 4; Humans; Hyperglycemia; Immunoglobulin E; Inflammation; Insulin Resistance; Interleukin-10; Mitochondrial Turnover; Muscle, Skeletal; Neoplasms; Neuroprotective Agents; NF-kappa B; Obesity; Oxidative Stress; Tumor Necrosis Factors; Weight Loss

2013
The cariogenicity of snack foods and confections.
    Journal of the American Dental Association (1939), 1975, Volume: 90, Issue:1

    Topics: Acids; Adolescent; Adult; Aged; Animals; Candy; Carbonated Beverages; Child; Child, Preschool; Cricetinae; Dental Caries; Dental Enamel; Dental Plaque; Diet; Diet, Cariogenic; Dietary Carbohydrates; Disease Models, Animal; Feeding Behavior; Female; Humans; Hydrogen-Ion Concentration; Infant; Male; Middle Aged; Rats; Saliva; Sex Factors; Sucrose; United States

1975

Trials

2 trial(s) available for cocaine and Disease Models, Animal

ArticleYear
Transplacental cocaine exposure: a mouse model demonstrating neuroanatomic and behavioral abnormalities.
    Journal of child neurology, 1994, Volume: 9, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Brain; Brain Diseases; Cocaine; Disease Models, Animal; Embryonic and Fetal Development; Female; Growth Disorders; Maternal-Fetal Exchange; Mice; Neurons; Pregnancy

1994
Addiction and the potential for therapeutic drug development.
    EXS, 1994, Volume: 71

    Topics: Alcoholism; Animals; Cocaine; Disease Models, Animal; Double-Blind Method; Humans; Research Design; Ritanserin; Substance-Related Disorders

1994

Other Studies

686 other study(ies) available for cocaine and Disease Models, Animal

ArticleYear
The effect of environmental factors of the coking plant on the enzymatic activity of rabbit oral mucosa.
    Folia histochemica et cytochemica, 1977, Volume: 15, Issue:1

    Topics: Animals; Coal; Coke; Disease Models, Animal; Electron Transport Complex IV; Environmental Exposure; Epithelium; Glucosephosphate Dehydrogenase; Histocytochemistry; L-Lactate Dehydrogenase; Leukoplakia, Oral; Male; Mouth Mucosa; Phosphorylases; Rabbits; Succinate Dehydrogenase

1977
[Evaluation of the fibrogenic effect of coke dust on the lungs and internal organs of experimental animals].
    Medycyna pracy, 1991, Volume: 42, Issue:5

    Topics: Air Pollutants; Animals; Chemical Industry; Coke; Disease Models, Animal; Dust; Ferric Compounds; Hydroxyproline; Lung; Male; Pulmonary Fibrosis; Rats; Rats, Inbred Strains; Silicon Dioxide; Silicosis

1991
The role of the dorsal striatum in a mouse model for fragile X syndrome: Behavioral and dendritic spine assessment.
    Brain research, 2022, 11-15, Volume: 1795

    Topics: Animals; Cocaine; Dendritic Spines; Disease Models, Animal; Fragile X Mental Retardation Protein; Fragile X Syndrome; Mice; Mice, Knockout

2022
Interaction between maternal immune activation and peripubertal stress in rats: impact on cocaine addiction-like behaviour, morphofunctional brain parameters and striatal transcriptome.
    Translational psychiatry, 2023, 03-08, Volume: 13, Issue:1

    Topics: Animals; Behavior, Animal; Brain; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Female; Humans; Male; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Transcriptome

2023
Chronic poly-drug administration damages adult mouse brain neural stem cells.
    Brain research, 2019, 11-15, Volume: 1723

    Topics: Adult Stem Cells; Age Factors; Animals; Brain; Cell Differentiation; Cocaine; Disease Models, Animal; Ethanol; Female; Hippocampus; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Regeneration; Neural Stem Cells; Neurogenesis; Sex Factors

2019
Within-animal comparisons of novelty and cocaine neuronal ensemble overlap in the nucleus accumbens and prefrontal cortex.
    Behavioural brain research, 2020, 02-03, Volume: 379

    Topics: Animals; Behavior, Animal; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Exploratory Behavior; Female; Male; Mice; Mice, Transgenic; Nucleus Accumbens; Prefrontal Cortex; Reward; Sex Characteristics; Stress, Psychological

2020
Ubiquitin-proteasomal regulation of chromatin remodeler INO80 in the nucleus accumbens mediates persistent cocaine craving.
    Science advances, 2019, Volume: 5, Issue:10

    Topics: Animals; ATPases Associated with Diverse Cellular Activities; Chromatin; Cocaine; Disease Models, Animal; Drug-Seeking Behavior; Early Growth Response Protein 1; Humans; Male; Nucleus Accumbens; Promoter Regions, Genetic; Protein Binding; Protein Subunits; Rats; Rats, Sprague-Dawley; Self Administration; Substance Withdrawal Syndrome; Ubiquitin-Protein Ligases

2019
A Novel Transgenic Mouse Model to Investigate the Cell-Autonomous Effects of torsinA(ΔE) Expression in Striatal Output Neurons.
    Neuroscience, 2019, 12-01, Volume: 422

    Topics: Animals; Cocaine; Corpus Striatum; Disease Models, Animal; Dopamine; Dystonia; Electric Stimulation; Female; Gene Expression; Male; Mice; Mice, Transgenic; Molecular Chaperones; Motor Skills; Mutation; Neural Pathways; Neurons; Substantia Nigra; Trihexyphenidyl

2019
Reward and immune responses in adolescent females following experimental traumatic brain injury.
    Behavioural brain research, 2020, 02-03, Volume: 379

    Topics: Animals; Behavior, Addictive; Behavior, Animal; Brain Injuries, Traumatic; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Estradiol; Female; Inflammation; Male; Mice; Mice, Inbred C57BL; Neuroprotection; Progesterone; Reward; Sex Characteristics

2020
Alpha-synuclein is strategically positioned for afferent modulation of midbrain dopamine neurons and is essential for cocaine preference.
    Communications biology, 2019, Volume: 2

    Topics: alpha-Synuclein; Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Disease Susceptibility; Dopaminergic Neurons; Extracellular Space; Immunohistochemistry; Male; Mesencephalon; Mice; Mice, Knockout; Models, Biological; Motivation; Motor Activity; Reward; Signal Transduction

2019
Microglial activation increases cocaine self-administration following adolescent nicotine exposure.
    Nature communications, 2020, 01-16, Volume: 11, Issue:1

    Topics: Aminopyridines; Animals; Chemokine CX3CL1; Cocaine; Disease Models, Animal; Drug-Seeking Behavior; Electronic Nicotine Delivery Systems; Female; Gene Expression Regulation; Male; Microglia; Minocycline; Nicotine; Phenotype; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Reinforcement, Psychology; Reward; Self Administration; Synaptophysin

2020
Alpha-1 Adrenergic Receptors Modulate Glutamate and GABA Neurotransmission onto Ventral Tegmental Dopamine Neurons during Cocaine Sensitization.
    International journal of molecular sciences, 2020, Jan-25, Volume: 21, Issue:3

    Topics: Action Potentials; Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopaminergic Neurons; gamma-Aminobutyric Acid; Glutamic Acid; Male; Models, Biological; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Receptors, Adrenergic, alpha-1; Signal Transduction; Ventral Tegmental Area

2020
Behavioral and neuroimmune characterization of resilience to social stress: Rewarding effects of cocaine.
    Adicciones, 2021, Nov-05, Volume: 33, Issue:4

    Topics: Animals; Cocaine; Disease Models, Animal; Humans; Male; Mice; Reward; Stress, Psychological

2021
The effects of combined intravenous cocaine and ethanol self-administration on the behavioral and amino acid profile of young adult rats.
    PloS one, 2020, Volume: 15, Issue:3

    Topics: Animals; Behavior, Animal; Cocaine; Disease Models, Animal; Ethanol; Female; Humans; Infusions, Intravenous; Male; Rats; Reinforcement, Psychology; Self Administration; Sex Factors; Substance-Related Disorders; Tyrosine

2020
[Cocaine peaks and troughs. Modeling pathological drug use in rats].
    Medecine sciences : M/S, 2020, Volume: 36, Issue:3

    Topics: Administration, Oral; Animals; Behavior, Addictive; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Computer Graphics; Disease Models, Animal; Humans; Rats

2020
Maternal immune activation is associated with a lower number of dopamine receptor 3-expressing granulocytes with no alterations in cocaine reward, resistance to extinction or cue-induced reinstatement.
    Pharmacology, biochemistry, and behavior, 2020, Volume: 193

    Topics: Animals; Biomarkers; Cells, Cultured; Cocaine; Cocaine-Related Disorders; Cues; Disease Models, Animal; Drug-Seeking Behavior; Extinction, Psychological; Female; Granulocytes; Leukocyte Count; Lipopolysaccharides; Male; Pregnancy; Prepulse Inhibition; Rats; Rats, Inbred Lew; Receptor, Cannabinoid, CB2; Receptors, Dopamine D3; Reward; Schizophrenia; Self Administration; T-Lymphocytes

2020
The impact of GABA
    European journal of pharmacology, 2020, Sep-15, Volume: 883

    Topics: Animals; Baclofen; Behavior, Addictive; Behavior, Animal; Brain; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Depression; Disease Models, Animal; Drug-Seeking Behavior; GABA-B Receptor Agonists; Male; Organophosphorus Compounds; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B; Reinforcement, Psychology; Reward

2020
Sex differences in the effects of a combined behavioral and pharmacological treatment strategy for cocaine relapse prevention in an animal model of cue exposure therapy.
    Behavioural brain research, 2020, 10-01, Volume: 395

    Topics: Animals; Behavior Therapy; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Disease Models, Animal; Extinction, Psychological; Female; Implosive Therapy; Learning; Male; Rats; Rats, Wistar; Secondary Prevention; Self Administration; Sex Factors

2020
Orbitofrontal-striatal potentiation underlies cocaine-induced hyperactivity.
    Nature communications, 2020, 08-10, Volume: 11, Issue:1

    Topics: Animals; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Corpus Striatum; Disease Models, Animal; Dopamine; Female; Hyperkinesis; Locomotion; Male; Mice; Mice, Inbred C57BL; Neurons; Optogenetics; Prefrontal Cortex

2020
Risperidone and 5-HT2A Receptor Antagonists Attenuate and Reverse Cocaine-Induced Hyperthermia in Rats.
    The international journal of neuropsychopharmacology, 2020, 12-29, Volume: 23, Issue:12

    Topics: Animals; Benzazepines; Cocaine; Disease Models, Animal; Dopamine Antagonists; Dopamine Uptake Inhibitors; Haloperidol; Hyperthermia; Ketanserin; Male; Rats; Rats, Wistar; Risperidone; Ritanserin; Serotonin 5-HT2 Receptor Antagonists

2020
Effects of High-Fat Diet and Maternal Binge-Like Alcohol Consumption and Their Influence on Cocaine Response in Female Mice Offspring.
    The international journal of neuropsychopharmacology, 2021, 01-20, Volume: 24, Issue:1

    Topics: Age Factors; Animals; Animals, Suckling; Binge Drinking; Cocaine; Diet, High-Fat; Disease Models, Animal; Dopamine Uptake Inhibitors; Female; Lactation; Mice; Mice, Inbred C57BL; Pregnancy; Prenatal Exposure Delayed Effects

2021
Elevated GABA levels in the medial prefrontal cortex and lower estrogen levels abolish cocaine sensitization behavior in ovariectomized female rats.
    Brain research, 2020, 12-15, Volume: 1749

    Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Estradiol; Female; gamma-Aminobutyric Acid; Glutamic Acid; Microdialysis; Motor Activity; Ovariectomy; Prefrontal Cortex; Rats; Rats, Wistar; Taurine

2020
Cocaine Administration and Its Abstinence Conditions Modulate Neuroglia.
    International journal of molecular sciences, 2020, Oct-27, Volume: 21, Issue:21

    Topics: 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase; Animals; B7-2 Antigen; Blood Proteins; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Down-Regulation; Extinction, Psychological; Gene Expression Profiling; Gene Expression Regulation; Gene Regulatory Networks; Hippocampus; Male; Neuroglia; Oligodendroglia; Phosphoproteins; Rats; RGS Proteins; Self Administration; Transcription Factors

2020
LSP2-9166, an orthosteric mGlu4 and mGlu7 receptor agonist, reduces cocaine self-administration under a progressive ratio schedule in rats.
    Neuroscience letters, 2021, 11-01, Volume: 764

    Topics: Administration, Intravenous; Aminobutyrates; Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Glutamic Acid; Humans; Male; Motivation; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Reinforcement, Psychology; Self Administration; Synaptic Transmission

2021
Effects of JL13, a pyridobenzoxazepine compound, in dopaminergic and glutamatergic models of antipsychotic activity.
    Behavioural pharmacology, 2021, 02-01, Volume: 32, Issue:1

    Topics: Animals; Antipsychotic Agents; Cocaine; Disease Models, Animal; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Glutamic Acid; Ketamine; Locomotion; Male; Mice; Oxazepines; Piperazines; Pyridines; Reflex, Startle; Schizophrenia

2021
Gene expression in the striatum of cynomolgus monkeys after chronic administration of cocaine and heroin.
    Basic & clinical pharmacology & toxicology, 2021, Volume: 128, Issue:5

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Disease Models, Animal; Female; Gene Expression Regulation; Heroin; Heroin Dependence; Humans; Kinesins; Macaca fascicularis; Neuronal Plasticity; RNA-Seq; Self Administration; Transcriptome

2021
Chronic opipramol treatment extinguishes cocaine craving through Rac1 in responders: A rat model study.
    Addiction biology, 2021, Volume: 26, Issue:5

    Topics: Animals; Antidepressive Agents, Tricyclic; Cocaine; Cocaine-Related Disorders; Craving; Cues; Disease Models, Animal; Drug-Seeking Behavior; Extinction, Psychological; Male; Neurons; Nucleus Accumbens; Opipramol; rac1 GTP-Binding Protein; Rats; Rats, Sprague-Dawley; Self Administration; Substance Withdrawal Syndrome

2021
Prefrontal cortex nicotinic receptor inhibition by methyllycaconitine impaired cocaine-associated memory acquisition and retrieval.
    Behavioural brain research, 2021, 05-21, Volume: 406

    Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Behavior, Animal; Central Nervous System Sensitization; Cocaine; Cocaine-Related Disorders; Conditioning, Classical; Disease Models, Animal; Dopamine Uptake Inhibitors; Memory Consolidation; Mental Recall; Nicotinic Antagonists; Prefrontal Cortex; Rats; Rats, Wistar

2021
Comparison of the sensitizing effects of cocaine and ethanol on histone deacetylase isoforms in the rat brain.
    Neuroreport, 2021, 04-07, Volume: 32, Issue:6

    Topics: Alcoholism; Animals; Brain; Central Nervous System Depressants; Central Nervous System Sensitization; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Epigenesis, Genetic; Ethanol; Histone Deacetylase 1; Histone Deacetylase 2; Histone Deacetylases; Male; Neostriatum; Prefrontal Cortex; Rats; RNA, Messenger; Transcriptome

2021
Novelty-induced hyperactivity and suppressed cocaine induced locomotor activation in mice lacking threonine 53 phosphorylation of dopamine transporter.
    Behavioural brain research, 2021, 06-25, Volume: 408

    Topics: Animals; Behavior, Animal; Cocaine; Corpus Striatum; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Locomotion; MAP Kinase Signaling System; Mice; Mice, Transgenic; Phosphorylation; Threonine

2021
S-Equol mitigates motivational deficits and dysregulation associated with HIV-1.
    Scientific reports, 2021, 06-04, Volume: 11, Issue:1

    Topics: Animals; Animals, Genetically Modified; Anti-HIV Agents; Apathy; Behavior, Addictive; Behavior, Animal; Catheterization; Choice Behavior; Cocaine; Dendrites; Dendritic Spines; Disease Models, Animal; Equol; Estrogen Receptor beta; Female; Genotype; HIV Infections; HIV Seropositivity; Jugular Veins; Motivation; Neurocognitive Disorders; Rats; Sucrose; Treatment Outcome

2021
Spontaneously Hypertensive Rat substrains show differences in model traits for addiction risk and cocaine self-administration: Implications for a novel rat reduced complexity cross.
    Behavioural brain research, 2021, 08-06, Volume: 411

    Topics: Animals; Behavior, Addictive; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Male; Phenotype; Rats; Rats, Inbred SHR; Risk Factors; Self Administration; Species Specificity

2021
CB1R activation in nucleus accumbens core promotes stress-induced reinstatement of cocaine seeking by elevating extracellular glutamate in a drug-paired context.
    Scientific reports, 2021, 06-21, Volume: 11, Issue:1

    Topics: Animals; Behavior, Animal; Biomarkers; Cocaine; Cocaine-Related Disorders; Conditioning, Classical; Disease Models, Animal; Disease Susceptibility; Extinction, Psychological; Extracellular Space; Glutamic Acid; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Stress, Physiological

2021
Sex differences in behavioral traits related with high sensitivity to the reinforcing effects of cocaine.
    Behavioural brain research, 2021, 09-24, Volume: 414

    Topics: Animals; Anxiety; Behavior, Animal; Cocaine; Depression; Disease Models, Animal; Dopamine Uptake Inhibitors; Exploratory Behavior; Female; Locomotion; Male; Mice; Reinforcement, Psychology; Sex Characteristics

2021
Prepulse inhibition can predict the motivational effects of cocaine in female mice exposed to maternal separation.
    Behavioural brain research, 2022, 01-07, Volume: 416

    Topics: Anhedonia; Animals; Cocaine; Conditioning, Operant; Disease Models, Animal; Dopamine Uptake Inhibitors; Female; Maternal Deprivation; Mice; Motivation; Prepulse Inhibition; Reflex, Startle; Self Administration; Weaning

2022
Longitudinal Changes in Brain Metabolic Activity after Withdrawal from Escalation of Cocaine Self-Administration.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2017, Volume: 42, Issue:10

    Topics: Animals; Brain; Brain Mapping; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Fluorodeoxyglucose F18; Longitudinal Studies; Male; Positron-Emission Tomography; Radiopharmaceuticals; Rats, Sprague-Dawley; Self Administration

2017
Drug-seeking motivation level in male rats determines offspring susceptibility or resistance to cocaine-seeking behaviour.
    Nature communications, 2017, 05-30, Volume: 8

    Topics: Animals; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; DNA Methylation; Drug-Seeking Behavior; Epigenesis, Genetic; Female; Male; Maze Learning; Motivation; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Self Administration

2017
Disruption of GluA2 phosphorylation potentiates stress responsivity.
    Behavioural brain research, 2017, 08-30, Volume: 333

    Topics: Alanine; Animals; Cocaine; Conditioning, Operant; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Extinction, Psychological; Female; Gene Expression Regulation; Lysine; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Phosphorylation; Protein Kinase C; Receptors, AMPA; Stress, Psychological; Swimming

2017
Sensitivity to cocaine in adult mice is due to interplay between genetic makeup, early environment and later experience.
    Neuropharmacology, 2017, Volume: 125

    Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Disease Models, Animal; Disease Susceptibility; Dopamine Uptake Inhibitors; Female; Gene-Environment Interaction; Genetic Predisposition to Disease; Mice, Inbred C57BL; Mice, Inbred DBA; Proto-Oncogene Proteins c-fos; Random Allocation; Reward; Spatial Behavior; Species Specificity

2017
Binge-pattern cocaine administration causes long-lasting behavioral hyperarousal but does not enhance vulnerability to single prolonged stress in rats.
    Psychiatry research, 2017, Volume: 257

    Topics: Animals; Anxiety; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Male; Psychomotor Agitation; Rats; Rats, Sprague-Dawley; Stress, Psychological

2017
Effects of escitalopram and imipramine on cocaine reinforcement and drug-seeking behaviors in a rat model of depression.
    Brain research, 2017, Oct-15, Volume: 1673

    Topics: Animals; Citalopram; Cocaine; Cocaine-Related Disorders; Cues; Depressive Disorder; Disease Models, Animal; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Extinction, Psychological; Imipramine; Male; Motor Activity; Olfactory Bulb; Psychotropic Drugs; Rats, Wistar; Reinforcement, Psychology; Self Administration

2017
Persistent effects of acute stress on fear and drug-seeking in a novel model of the comorbidity between post-traumatic stress disorder and addiction.
    Learning & memory (Cold Spring Harbor, N.Y.), 2017, Volume: 24, Issue:9

    Topics: Animals; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Corticosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Electroshock; Fear; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Rats; Rats, Long-Evans; Self Administration; Stress Disorders, Post-Traumatic

2017
Hyperactive TGF-β Signaling in Smooth Muscle Cells Exposed to HIV-protein(s) and Cocaine: Role in Pulmonary Vasculopathy.
    Scientific reports, 2017, 09-05, Volume: 7, Issue:1

    Topics: Animals; Bone Morphogenetic Protein Receptors, Type II; Cell Proliferation; Cocaine; Disease Models, Animal; HIV Infections; Humans; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Pulmonary Artery; Rats; Rats, Transgenic; Receptors, Transforming Growth Factor beta; Signal Transduction; Smad Proteins; tat Gene Products, Human Immunodeficiency Virus; Transforming Growth Factor beta; Viral Proteins

2017
Chronic treatment with Tempol during acquisition or withdrawal from CPP abolishes the expression of cocaine reward and diminishes oxidative damage.
    Scientific reports, 2017, 09-11, Volume: 7, Issue:1

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Cyclic N-Oxides; Disease Models, Animal; Lipid Peroxidation; Male; Nitric Oxide; Nitrites; Oxidative Stress; Prefrontal Cortex; Rats; Reinforcement, Psychology; Reward; Spin Labels; Treatment Outcome

2017
Hypocretin receptor 1 knockdown in the ventral tegmental area attenuates mesolimbic dopamine signaling and reduces motivation for cocaine.
    Addiction biology, 2018, Volume: 23, Issue:5

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine; Limbic Lobe; Male; Mesencephalon; Motivation; Orexin Receptors; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Reward; Self Administration; Signal Transduction; Ventral Tegmental Area

2018
Oxytocin Reduces Cocaine Cued Fos Activation in a Regionally Specific Manner.
    The international journal of neuropsychopharmacology, 2017, 10-01, Volume: 20, Issue:10

    Topics: Animals; Brain; Central Nervous System Agents; Cocaine; Cocaine-Related Disorders; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Female; Male; Neurons; Oxytocin; Proto-Oncogene Proteins c-fos; Rats, Sprague-Dawley; Self Administration

2017
Housing conditions modulate the reinforcing properties of cocaine in adolescent mice that binge on fat.
    Physiology & behavior, 2018, Jan-01, Volume: 183

    Topics: Animals; Animals, Outbred Strains; Anxiety; Bulimia; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Corticosterone; Diet, High-Fat; Disease Models, Animal; Dopamine Uptake Inhibitors; Housing, Animal; Leptin; Male; Mice; Random Allocation; Reward; Social Isolation; Spatial Behavior

2018
Use of fast-scan cyclic voltammetry to assess phasic dopamine release in rat models of early postpartum maternal behavior and neglect.
    Behavioural pharmacology, 2017, Volume: 28, Issue:8

    Topics: Animals; Animals, Newborn; Catheters, Indwelling; Cocaine; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Electrodes, Implanted; Maternal Behavior; Postpartum Period; Random Allocation; Rats, Sprague-Dawley; Social Isolation; Urine

2017
High and escalating levels of cocaine intake are dissociable from subsequent incentive motivation for the drug in rats.
    Psychopharmacology, 2018, Volume: 235, Issue:1

    Topics: Animals; Behavior, Addictive; Brain; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Male; Motivation; Rats; Reinforcement, Psychology; Self Administration

2018
Behavioural and computational methods reveal differential effects for how delayed and rapid onset antidepressants effect decision making in rats.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2017, Volume: 27, Issue:12

    Topics: Acoustic Stimulation; Amphetamine; Analgesics; Animals; Antidepressive Agents; Association Learning; Central Nervous System Stimulants; Cocaine; Conditioning, Classical; Decision Making; Depressive Disorder, Major; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fluoxetine; Ketamine; Male; Models, Biological; Phencyclidine; Rats; Reaction Time; Time Factors

2017
Dissociation of place preference and tolerance responses to sucrose using a dopamine antagonist in the planarian.
    Psychopharmacology, 2018, Volume: 235, Issue:3

    Topics: Animals; Behavior, Addictive; Benzazepines; Cocaine; Conditioning, Classical; Disease Models, Animal; Dopamine Antagonists; Drug Tolerance; Male; Planarians; Reward; Sucrose

2018
Longer treatment with alternative non-drug reinforcement fails to reduce resurgence of cocaine or alcohol seeking in rats.
    Behavioural brain research, 2018, 04-02, Volume: 341

    Topics: Alcoholism; Animals; Central Nervous System Depressants; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Ethanol; Extinction, Psychological; Male; Rats, Long-Evans; Recurrence; Reinforcement, Psychology; Self Administration; Time Factors; Treatment Failure

2018
Chronic paroxetine treatment prevents disruption of methamphetamine-sensitive circadian oscillator in a transgenic mouse model of Huntington's disease.
    Neuropharmacology, 2018, 03-15, Volume: 131

    Topics: Animals; Central Nervous System Stimulants; Circadian Clocks; Circadian Rhythm; Cocaine; Disease Models, Animal; Female; Huntington Disease; Male; Methamphetamine; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Motor Activity; Paroxetine; Receptors, Dopamine; Selective Serotonin Reuptake Inhibitors; Serotonin; Synaptic Transmission; Vesicular Monoamine Transport Proteins

2018
A-Kinase Anchoring Protein 150 (AKAP150) Promotes Cocaine Reinstatement by Increasing AMPA Receptor Transmission in the Accumbens Shell.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2018, Volume: 43, Issue:6

    Topics: A Kinase Anchor Proteins; Animals; Cocaine; Cocaine-Related Disorders; Dietary Sucrose; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Excitatory Postsynaptic Potentials; Genetic Vectors; Nucleus Accumbens; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Dopamine D1; Recurrence; Self Administration; Synaptic Transmission

2018
Cocaine and HIV-1 Tat disrupt cholesterol homeostasis in astrocytes: Implications for HIV-associated neurocognitive disorders in cocaine user patients.
    Glia, 2018, Volume: 66, Issue:4

    Topics: AIDS Dementia Complex; Animals; Astrocytes; Brain; Cells, Cultured; Cholesterol; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Female; HIV-1; Homeostasis; Humans; Liver X Receptors; Male; Mice, Inbred C57BL; Mice, Transgenic; Neurons; tat Gene Products, Human Immunodeficiency Virus

2018
Median and Dorsal Raphe Serotonergic Neurons Control Moderate Versus Compulsive Cocaine Intake.
    Biological psychiatry, 2018, 06-15, Volume: 83, Issue:12

    Topics: Amygdala; Anesthetics, Local; Animals; Anxiety; Cocaine; Compulsive Behavior; Corticotropin-Releasing Hormone; Disease Models, Animal; Dorsal Raphe Nucleus; Gene Expression Regulation; Locomotion; Male; Maze Learning; Midbrain Raphe Nuclei; Motivation; Paraventricular Hypothalamic Nucleus; Rats; Rats, Wistar; RNA, Small Interfering; Self Administration; Serotonergic Neurons; Serotonin; Serotonin Plasma Membrane Transport Proteins; Time Factors; Transduction, Genetic

2018
Cocaine Exposure Increases Blood Pressure and Aortic Stiffness via the miR-30c-5p-Malic Enzyme 1-Reactive Oxygen Species Pathway.
    Hypertension (Dallas, Tex. : 1979), 2018, Volume: 71, Issue:4

    Topics: Animals; Blood Pressure; Cardiovascular Diseases; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Down-Regulation; Injections; Malate Dehydrogenase; Mice; MicroRNAs; Oxidation-Reduction; Reactive Oxygen Species; Signal Transduction; Vascular Stiffness; Vasoconstrictor Agents

2018
Regionally Specific Effects of Oxytocin on Reinstatement of Cocaine Seeking in Male and Female Rats.
    The international journal of neuropsychopharmacology, 2018, 07-01, Volume: 21, Issue:7

    Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Female; Glutamic Acid; Male; Nucleus Accumbens; Oxytocin; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology

2018
Efficacy and side effects of baclofen and the novel GABA
    Psychopharmacology, 2018, Volume: 235, Issue:7

    Topics: Alcoholism; Allosteric Regulation; Animals; Baclofen; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; GABA-B Receptor Agonists; Male; Pyrazoles; Pyrimidines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, GABA-B; Self Administration; Treatment Outcome

2018
Chronic restraint stress during withdrawal increases vulnerability to drug priming-induced cocaine seeking via a dopamine D1-like receptor-mediated mechanism.
    Drug and alcohol dependence, 2018, 06-01, Volume: 187

    Topics: Animals; Benzazepines; Cocaine; Cocaine-Related Disorders; Cues; Disease Models, Animal; Dopamine Antagonists; Drug-Seeking Behavior; Extinction, Psychological; Male; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Repetition Priming; Restraint, Physical; Self Administration; Stress, Psychological

2018
Cocaine Place Conditioning Strengthens Location-Specific Hippocampal Coupling to the Nucleus Accumbens.
    Neuron, 2018, 06-06, Volume: 98, Issue:5

    Topics: Animals; CA1 Region, Hippocampal; Cocaine; Cocaine-Related Disorders; Conditioning, Classical; Disease Models, Animal; Dopamine Uptake Inhibitors; Hippocampus; Interneurons; Mice; Neural Pathways; Neurons; Nucleus Accumbens; Pyramidal Cells; Receptors, Dopamine D2

2018
HIV-1 proteins dysregulate motivational processes and dopamine circuitry.
    Scientific reports, 2018, 05-18, Volume: 8, Issue:1

    Topics: Animals; Choice Behavior; Cocaine; Corpus Striatum; Disease Models, Animal; Dopamine; HIV Infections; HIV-1; Human Immunodeficiency Virus Proteins; Neostriatum; Rats; Rats, Inbred F344; Rats, Transgenic; Reinforcement, Psychology; Self Administration; Sucrose

2018
Revisiting long-access versus short-access cocaine self-administration in rats: intermittent intake promotes addiction symptoms independent of session length.
    Addiction biology, 2019, Volume: 24, Issue:4

    Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Male; Rats; Rats, Wistar; Reinforcement, Psychology; Self Administration; Time Factors

2019
Effects of lorcaserin and buspirone, administered alone and as a mixture, on cocaine self-administration in male and female rhesus monkeys.
    Experimental and clinical psychopharmacology, 2018, Volume: 26, Issue:5

    Topics: Animals; Behavior, Addictive; Benzazepines; Buspirone; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Combinations; Female; Macaca mulatta; Male; Serotonin Receptor Agonists

2018
Limited modulation of the abuse-related behavioral effects of d-methamphetamine by disulfiram.
    Experimental and clinical psychopharmacology, 2018, Volume: 26, Issue:5

    Topics: Acetaldehyde Dehydrogenase Inhibitors; Amphetamine-Related Disorders; Animals; Behavioral Symptoms; Central Nervous System Stimulants; Cocaine; Discrimination, Psychological; Disease Models, Animal; Disulfiram; Dose-Response Relationship, Drug; Female; Macaca mulatta; Male; Methamphetamine; Reinforcement, Psychology; Treatment Outcome

2018
Effects of Mild Blast Traumatic Brain Injury on Cognitive- and Addiction-Related Behaviors.
    Scientific reports, 2018, 07-02, Volume: 8, Issue:1

    Topics: Animals; Blast Injuries; Brain Concussion; Cocaine; Cognitive Dysfunction; Disease Models, Animal; Drug-Seeking Behavior; Male; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Self Administration; Visual Perception

2018
Transcriptome Sequencing Reveals Candidate NF-κB Target Genes Involved in Repeated Cocaine Administration.
    The international journal of neuropsychopharmacology, 2018, 07-01, Volume: 21, Issue:7

    Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Ditiocarb; Dopamine Uptake Inhibitors; Exome Sequencing; High-Throughput Nucleotide Sequencing; Mice; NF-kappa B; Prefrontal Cortex; Sequestering Agents

2018
The role of neuronal nitric oxide synthase in cocaine place preference and mu opioid receptor expression in the nucleus accumbens.
    Psychopharmacology, 2018, Volume: 235, Issue:9

    Topics: Analysis of Variance; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Classical; Disease Models, Animal; Male; Nitric Oxide Synthase Type I; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu

2018
Chronic forced exercise inhibits stress-induced reinstatement of cocaine conditioned place preference.
    Behavioural brain research, 2018, 11-01, Volume: 353

    Topics: Animals; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Corticosterone; Disease Models, Animal; Exercise Therapy; Extinction, Psychological; Female; Rats, Sprague-Dawley; Running; Secondary Prevention; Spatial Behavior; Stress, Psychological

2018
Cocaine self-administration is increased after frontal traumatic brain injury and associated with neuroinflammation.
    The European journal of neuroscience, 2019, Volume: 50, Issue:3

    Topics: Animals; Brain Injuries, Traumatic; Cocaine; Disease Models, Animal; Frontal Lobe; Inflammation; Male; Rats, Long-Evans; Rats, Sprague-Dawley; Self Administration

2019
Targeting VGLUT2 in Mature Dopamine Neurons Decreases Mesoaccumbal Glutamatergic Transmission and Identifies a Role for Glutamate Co-release in Synaptic Plasticity by Increasing Baseline AMPA/NMDA Ratio.
    Frontiers in neural circuits, 2018, Volume: 12

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamine; Animals; Behavior, Animal; Cocaine; Disease Models, Animal; Dopamine Agents; Dopaminergic Neurons; Glutamic Acid; Mice; Mice, Transgenic; N-Methylaspartate; Neuronal Plasticity; Nucleus Accumbens; Optogenetics; Patch-Clamp Techniques; Receptors, Dopamine D1; Substance-Related Disorders; Synaptic Transmission; Ventral Tegmental Area; Vesicular Glutamate Transport Protein 2

2018
A novel rat model of comorbid PTSD and addiction reveals intersections between stress susceptibility and enhanced cocaine seeking with a role for mGlu5 receptors.
    Translational psychiatry, 2018, 10-05, Volume: 8, Issue:1

    Topics: Animals; Anxiety; Behavior, Animal; Brain; Cocaine; Cocaine-Related Disorders; Comorbidity; Disease Models, Animal; Drug-Seeking Behavior; Extinction, Psychological; Fear; Male; Phenotype; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Resilience, Psychological; Stress Disorders, Post-Traumatic; Stress, Psychological; Thiazoles

2018
Prelimbic cortex is a common brain area activated during cue-induced reinstatement of cocaine and heroin seeking in a polydrug self-administration rat model.
    The European journal of neuroscience, 2019, Volume: 49, Issue:2

    Topics: Amygdala; Animals; Brain; Cocaine; Conditioning, Operant; Corpus Striatum; Cues; Disease Models, Animal; Drug-Seeking Behavior; Extinction, Psychological; Heroin; Male; Nucleus Accumbens; Prefrontal Cortex; Rats, Long-Evans

2019
phMRI, neurochemical and behavioral responses to psychostimulants distinguishing genetically selected alcohol-preferring from genetically heterogenous rats.
    Addiction biology, 2019, Volume: 24, Issue:5

    Topics: Alcoholism; Amphetamine; Amygdala; Animals; Brain; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Functional Neuroimaging; gamma-Aminobutyric Acid; Glutamic Acid; Locomotion; Magnetic Resonance Imaging; Microdialysis; Nucleus Accumbens; Rats; Self Administration

2019
Dysregulation of Neuronal Cholesterol Homeostasis upon Exposure to HIV-1 Tat and Cocaine Revealed by RNA-Sequencing.
    Scientific reports, 2018, 11-02, Volume: 8, Issue:1

    Topics: AIDS Dementia Complex; Animals; Biosynthetic Pathways; Cells, Cultured; Cholesterol; Cocaine; Cocaine-Related Disorders; Computational Biology; Disease Models, Animal; Gene Expression Profiling; Hippocampus; HIV-1; Humans; Lipid Metabolism; Macaca mulatta; Mice; Mice, Transgenic; Neurons; Primary Cell Culture; Rats; Sequence Analysis, RNA; tat Gene Products, Human Immunodeficiency Virus

2018
Overexpression of ASIC1A in the nucleus accumbens of rats potentiates cocaine-seeking behavior.
    Addiction biology, 2020, Volume: 25, Issue:2

    Topics: Acid Sensing Ion Channels; Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Gene Expression; Male; Nucleus Accumbens; Rats; Rats, Sprague-Dawley

2020
Intermittent intake of rapid cocaine injections promotes the risk of relapse and increases mesocorticolimbic BDNF levels during abstinence.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2019, Volume: 44, Issue:6

    Topics: Animals; Behavior, Animal; Brain; Brain-Derived Neurotrophic Factor; Cocaine; Cocaine-Related Disorders; Craving; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Nucleus Accumbens; Prefrontal Cortex; Rats; Reward; Self Administration; Time Factors; Ventral Tegmental Area

2019
Cocaine and cocaine expectancy increase growth hormone, ghrelin, GLP-1, IGF-1, adiponectin, and corticosterone while decreasing leptin, insulin, GIP, and prolactin.
    Pharmacology, biochemistry, and behavior, 2019, Volume: 176

    Topics: Adiponectin; Animals; Cocaine; Cocaine-Related Disorders; Corticosterone; Disease Models, Animal; Drug Substitution; Gastric Inhibitory Polypeptide; Ghrelin; Glucagon-Like Peptide 1; Growth Hormone; Injections, Intravenous; Insulin; Leptin; Prolactin; Rats; Reward; Saline Solution; Self Administration; Signal Transduction

2019
Oxytocin prevents the increase of cocaine-related responses produced by social defeat.
    Neuropharmacology, 2019, 03-01, Volume: 146

    Topics: Animals; Anxiety; Brain-Derived Neurotrophic Factor; Cocaine; Conditioning, Classical; Conditioning, Operant; Corpus Striatum; Disease Models, Animal; Hippocampus; Male; Mice; Oxytocin; Prefrontal Cortex; Reinforcement, Psychology; Reward; Self Administration; Stress, Psychological

2019
PI3K activation within ventromedial prefrontal cortex regulates the expression of drug-seeking in two rodent species.
    Addiction biology, 2019, Volume: 24, Issue:6

    Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Craving; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Learning; Mice; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Prefrontal Cortex; Proto-Oncogene Proteins c-akt; Rats; Self Administration; Wortmannin

2019
A Recombinant Humanized Anticocaine Monoclonal Antibody Alters the Urinary Clearance of Cocaine and Its Metabolites in Rats.
    Drug metabolism and disposition: the biological fate of chemicals, 2019, Volume: 47, Issue:3

    Topics: Animals; Antibodies, Monoclonal, Humanized; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Humans; Male; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Renal Elimination; Substance Abuse Detection

2019
Serotonin transporter inhibition and 5-HT
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2019, Volume: 44, Issue:5

    Topics: Animals; Behavior, Animal; Cocaine; Conditioning, Classical; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Fluoxetine; Locomotion; Methylphenidate; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Transgenic; Neostriatum; Receptor, Serotonin, 5-HT2C; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins

2019
Subthalamic nucleus mediates the modulation on cocaine self-administration induced by ultrasonic vocalization playback in rats.
    Addiction biology, 2020, Volume: 25, Issue:1

    Topics: Acoustic Stimulation; Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Emotions; Male; Rats; Self Administration; Subthalamic Nucleus; Sucrose; Ultrasonics; Vocalization, Animal

2020
Central nucleus of the amygdala as a common substrate of the incubation of drug and natural reinforcer seeking.
    Addiction biology, 2020, Volume: 25, Issue:2

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; Central Amygdaloid Nucleus; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Heroin; Male; Opioid-Related Disorders; Rats; Rats, Inbred Lew; Reinforcement, Psychology; Self Administration; Sucrose

2020
Cues play a critical role in estrous cycle-dependent enhancement of cocaine reinforcement.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2019, Volume: 44, Issue:7

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Classical; Conditioning, Operant; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Economics, Behavioral; Estrous Cycle; Female; Male; Rats, Sprague-Dawley; Reinforcement, Psychology

2019
The role of DNA methyltransferase activity in cocaine treatment and withdrawal in the nucleus accumbens of mice.
    Addiction biology, 2020, Volume: 25, Issue:1

    Topics: Animals; Cocaine; Disease Models, Animal; DNA Methylation; Dopamine Uptake Inhibitors; Male; Mice; Mice, Inbred C57BL; Nucleus Accumbens; Substance Withdrawal Syndrome

2020
Glutamatergic neurons in the medial prefrontal cortex mediate the formation and retrieval of cocaine-associated memories in mice.
    Addiction biology, 2020, Volume: 25, Issue:1

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Electrophysiology; Fluorescent Antibody Technique; GABAergic Neurons; Male; Memory; Mice; Mice, Inbred C57BL; Prefrontal Cortex

2020
Ultrahigh-resolution MRI reveals structural brain differences in serotonin transporter knockout rats after sucrose and cocaine self-administration.
    Addiction biology, 2020, Volume: 25, Issue:1

    Topics: Animals; Brain; Brain Mapping; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Magnetic Resonance Imaging; Rats; Self Administration; Serotonin Plasma Membrane Transport Proteins; Sucrose

2020
Adolescence versus adulthood: Differences in basal mesolimbic and nigrostriatal dopamine transmission and response to drugs of abuse.
    Addiction biology, 2020, Volume: 25, Issue:1

    Topics: Age Factors; Analgesics, Opioid; Animals; Brain; Cocaine; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Dronabinol; Ganglionic Stimulants; Male; Microdialysis; Morphine; Nicotine; Nucleus Accumbens; Psychotropic Drugs; Rats; Substance-Related Disorders; Synaptic Transmission

2020
The influence of sex and estrous cyclicity on cocaine and remifentanil demand in rats.
    Addiction biology, 2020, Volume: 25, Issue:1

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Estrous Cycle; Female; Male; Rats; Rats, Long-Evans; Remifentanil; Self Administration; Sex Factors; Substance-Related Disorders

2020
The effects of Pavlovian cue extinction and ceftriaxone on cocaine relapse after abstinence.
    Drug and alcohol dependence, 2019, 04-01, Volume: 197

    Topics: Animals; Anti-Bacterial Agents; Ceftriaxone; Cocaine; Cocaine-Related Disorders; Craving; Cues; Disease Models, Animal; Drug-Seeking Behavior; Extinction, Psychological; Male; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration

2019
Activation of AMPK-dependent autophagy in the nucleus accumbens opposes cocaine-induced behaviors of mice.
    Addiction biology, 2020, Volume: 25, Issue:2

    Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Male; Mice; Mice, Inbred C57BL; Nucleus Accumbens

2020
Discriminative stimuli are sufficient for incubation of cocaine craving.
    eLife, 2019, 02-25, Volume: 8

    Topics: Animals; Cocaine; Craving; Disease Models, Animal; Rats; Recurrence; Secondary Prevention; Substance-Related Disorders

2019
The transition to cocaine addiction: the importance of pharmacokinetics for preclinical models.
    Psychopharmacology, 2019, Volume: 236, Issue:4

    Topics: Animals; Behavior, Addictive; Brain; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Humans; Motivation; Rats, Sprague-Dawley; Self Administration

2019
Impaired decision making following escalation of cocaine self-administration predicts vulnerability to relapse in rats.
    Addiction biology, 2020, Volume: 25, Issue:3

    Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Decision Making; Disease Models, Animal; Dopamine Uptake Inhibitors; Extinction, Psychological; Male; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration

2020
Lateral septum inhibition reduces motivation for cocaine: Reversal by diazepam.
    Addiction biology, 2020, Volume: 25, Issue:2

    Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Diazepam; Disease Models, Animal; Dopamine Uptake Inhibitors; GABA Modulators; Male; Motivation; Rats; Rats, Sprague-Dawley; Septal Nuclei

2020
Epigenetic effects of paternal cocaine on reward stimulus behavior and accumbens gene expression in mice.
    Behavioural brain research, 2019, 07-23, Volume: 367

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Cytokines; Disease Models, Animal; Dopamine Uptake Inhibitors; Epigenesis, Genetic; Fathers; Female; Gene Expression Regulation; Inheritance Patterns; Male; Mice; Mice, Inbred C57BL; Nucleus Accumbens; Reward; Sequence Analysis, RNA; Sex Characteristics

2019
Neurobiological substrates of persistent working memory deficits and cocaine-seeking in the prelimbic cortex of rats with a history of extended access to cocaine self-administration.
    Neurobiology of learning and memory, 2019, Volume: 161

    Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Cognitive Dysfunction; Disease Models, Animal; Dopamine Uptake Inhibitors; Gyrus Cinguli; Male; Memory, Short-Term; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Self Administration

2019
Mirtazapine attenuates anxiety- and depression-like behaviors in rats during cocaine withdrawal.
    Journal of psychopharmacology (Oxford, England), 2019, Volume: 33, Issue:5

    Topics: Animals; Antidepressive Agents; Anxiety; Behavior, Animal; Cocaine; Depression; Disease Models, Animal; Dopamine Uptake Inhibitors; Male; Mirtazapine; Rats; Rats, Wistar; Substance Withdrawal Syndrome

2019
Neuronal HMGB1 in nucleus accumbens regulates cocaine reward memory.
    Addiction biology, 2020, Volume: 25, Issue:2

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; HMGB1 Protein; Male; Memory; Neurons; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reward

2020
Increased relapse to cocaine-seeking in a genetic model for depression.
    Addiction biology, 2020, Volume: 25, Issue:3

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cocaine; Depression; Depressive Disorder, Treatment-Resistant; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Prefrontal Cortex; Rats; Recurrence; Self Administration; Stress, Psychological

2020
Genetics of cocaine and methamphetamine consumption and preference in Drosophila melanogaster.
    PLoS genetics, 2019, Volume: 15, Issue:5

    Topics: Animals; Central Nervous System Stimulants; Cocaine; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Drosophila melanogaster; Drosophila Proteins; Feeding Behavior; Female; Gene Expression Profiling; Gene Expression Regulation; Gene Regulatory Networks; Genome, Insect; Male; Methamphetamine; Mushroom Bodies; RNA, Small Interfering; Sex Characteristics; Substance-Related Disorders

2019
Increased sensitivity to psychostimulants and GABAergic drugs in Lsamp-deficient mice.
    Pharmacology, biochemistry, and behavior, 2019, Volume: 183

    Topics: Alprazolam; Animals; Behavior, Animal; Cell Adhesion Molecules, Neuronal; Central Nervous System Depressants; Central Nervous System Stimulants; Cocaine; Diazepam; Disease Models, Animal; Dizocilpine Maleate; Ethanol; Female; GABA Modulators; Gene Knockout Techniques; GPI-Linked Proteins; Locomotion; Male; Maze Learning; Mice; Mice, Knockout; Morphine; Neuroprotective Agents; Phenotype; Receptors, GABA-A

2019
Preventative effects of aripiprazole and quetiapine on seizure and lethality in a mice cocaine toxicity model: an experimental study.
    The Journal of international medical research, 2019, Volume: 47, Issue:8

    Topics: Anesthetics, Local; Animals; Antipsychotic Agents; Aripiprazole; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Mice; Mice, Inbred BALB C; Quetiapine Fumarate; Seizures; Survival Rate

2019
Sex-dependent effects of early unstable post-natal environment on response to positive and negative stimuli in adult mice.
    Neuroscience, 2019, 08-10, Volume: 413

    Topics: Anhedonia; Animals; Behavior, Animal; Brain; Cocaine; Corticosterone; Disease Models, Animal; Dopamine Uptake Inhibitors; Female; Male; Maternal Deprivation; Mice, Inbred C57BL; Proto-Oncogene Proteins c-fos; Random Allocation; Sex Characteristics; Stress, Psychological

2019
N-Acetylcysteine treatment during acute stress prevents stress-induced augmentation of addictive drug use and relapse.
    Addiction biology, 2020, Volume: 25, Issue:5

    Topics: Acetylcysteine; Acute Disease; Alcohol-Related Disorders; Animals; Cocaine; Cocaine-Related Disorders; Cues; Disease Models, Animal; Drug-Seeking Behavior; Ethanol; Free Radical Scavengers; Male; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration; Stress, Psychological

2020
Dynamic CRMP2 Regulation of CaV2.2 in the Prefrontal Cortex Contributes to the Reinstatement of Cocaine Seeking.
    Molecular neurobiology, 2020, Volume: 57, Issue:1

    Topics: Animals; Calcium Channels, N-Type; Cocaine; Cues; Disease Models, Animal; Drug-Seeking Behavior; Intercellular Signaling Peptides and Proteins; Male; Nerve Tissue Proteins; Phosphorylation; Prefrontal Cortex; Protein Binding; Rats, Sprague-Dawley; Self Administration

2020
Role of BRD4 phosphorylation in the nucleus accumbens in relapse to cocaine-seeking behavior in mice.
    Addiction biology, 2020, Volume: 25, Issue:5

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Male; Mice; Mice, Inbred C57BL; Nuclear Proteins; Nucleus Accumbens; Phosphorylation; Recurrence; Self Administration; Transcription Factors

2020
Sex differences in cocaine self-administration behaviour under long access versus intermittent access conditions.
    Addiction biology, 2020, Volume: 25, Issue:5

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Drug Administration Schedule; Drug-Seeking Behavior; Female; Male; Rats; Rats, Wistar; Self Administration; Sex Factors

2020
LC/MS/MS evaluation of cocaine and its metabolites in different brain areas, peripheral organs and plasma in cocaine self-administering rats.
    Pharmacological reports : PR, 2012, Volume: 64, Issue:6

    Topics: Animals; Biotransformation; Brain; Central Nervous System Stimulants; Chromatography, Liquid; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Half-Life; Injections, Intravenous; Kidney; Liver; Male; Metabolic Clearance Rate; Myocardium; Rats; Rats, Wistar; Reproducibility of Results; Self Administration; Substance Withdrawal Syndrome; Tandem Mass Spectrometry; Tissue Distribution

2012
Validation of nigrostriatal positron emission tomography measures: critical limits.
    Annals of neurology, 2013, Volume: 73, Issue:3

    Topics: Animals; Cocaine; Corpus Striatum; Disease Models, Animal; Fluorodeoxyglucose F18; Macaca mulatta; Magnetic Resonance Imaging; Male; MPTP Poisoning; Positron-Emission Tomography; Protein Binding; Radiopharmaceuticals; Reproducibility of Results; Substantia Nigra; Tetrabenazine

2013
Effect of chronic heroin and cocaine administration on global DNA methylation in brain and liver.
    Toxicology letters, 2013, Apr-26, Volume: 218, Issue:3

    Topics: Animals; Biomarkers; Brain; Chromatography, High Pressure Liquid; Cocaine; Cocaine-Related Disorders; Deoxycytidine; Disease Models, Animal; DNA Methylation; Heroin; Heroin Dependence; Liver; Male; Mice; Mice, Inbred C57BL; Spectrophotometry, Ultraviolet; Time Factors

2013
Relapse to cocaine-seeking after abstinence is regulated by cAMP-dependent protein kinase A in the prefrontal cortex.
    Addiction biology, 2014, Volume: 19, Issue:1

    Topics: Analysis of Variance; Animals; Blotting, Western; Cocaine; CREB-Binding Protein; Cues; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Male; Neuronal Plasticity; Nucleus Accumbens; Phosphoproteins; Phosphorylation; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Recurrence; Self Administration; Synapsins; Thionucleotides

2014
Prior access to a sweet is more protective against cocaine self-administration in female rats than in male rats.
    Physiology & behavior, 2013, Mar-15, Volume: 112-113

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Disease Models, Animal; Drug Administration Schedule; Female; Male; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Reinforcement, Psychology; Saccharin; Self Administration; Sex Characteristics; Statistics as Topic; Sweetening Agents; Taste; Water Deprivation

2013
Adolescents are more vulnerable to cocaine addiction: behavioral and electrophysiological evidence.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013, Mar-13, Volume: 33, Issue:11

    Topics: Action Potentials; Age Factors; Aging; Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Brain; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dopaminergic Neurons; Dose-Response Relationship, Drug; Male; Quinpirole; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Salicylamides; Self Administration; Time Factors; Ventral Tegmental Area

2013
Effect of post-trial L-NAME administration on cocaine sensitization.
    The International journal of neuroscience, 2013, Volume: 123, Issue:9

    Topics: Analysis of Variance; Animals; Cocaine; Conditioning, Operant; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug Administration Schedule; Drug Interactions; Enzyme Inhibitors; Locomotion; Male; NG-Nitroarginine Methyl Ester; Rats; Rats, Long-Evans; Time Factors

2013
Cue-induced resumption of heroin and cocaine seeking in rats using a conflict model of abstinence and relapse.
    Psychopharmacology, 2013, Volume: 228, Issue:4

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Conflict, Psychological; Cues; Disease Models, Animal; Electroshock; Extinction, Psychological; Heroin; Heroin Dependence; Male; Rats; Rats, Long-Evans; Recurrence; Self Administration

2013
A novel model of chronic sleep restriction reveals an increase in the perceived incentive reward value of cocaine in high drug-taking rats.
    Pharmacology, biochemistry, and behavior, 2013, Volume: 109

    Topics: Animals; Chronic Disease; Cocaine; Disease Models, Animal; Electroencephalography; Electromyography; Male; Motivation; Rats; Rats, Sprague-Dawley; Self Administration; Sleep Deprivation

2013
The role of ventral and dorsal striatum mGluR5 in relapse to cocaine-seeking and extinction learning.
    Addiction biology, 2014, Volume: 19, Issue:1

    Topics: Allosteric Regulation; Analysis of Variance; Animals; Basal Ganglia; Biotinylation; Blotting, Western; Cocaine; Cocaine-Related Disorders; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Electrophysiological Phenomena; Extinction, Psychological; Infusions, Intravenous; Locomotion; Long-Term Synaptic Depression; Male; Microinjections; Pyridines; Rats; Receptor, Metabotropic Glutamate 5; Recurrence; Self Administration; Sucrose; Thiazoles

2014
Differential behavioral reinforcement effects of dopamine receptor agonists in the rat with bilateral lesion of the posterior ventral tegmental area.
    Behavioural brain research, 2013, Sep-01, Volume: 252

    Topics: Adrenergic Agents; Analysis of Variance; Animals; Body Weight; Brain; Cocaine; Conditioning, Operant; Disease Models, Animal; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine Uptake Inhibitors; Gait Disorders, Neurologic; Male; Motivation; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Reinforcement, Psychology; Time Factors; Tyrosine 3-Monooxygenase; Ventral Tegmental Area

2013
Cocaine tolerance in honey bees.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: Animals; Bees; Behavior, Animal; Biogenic Amines; Brain; Cocaine; Disease Models, Animal; Drug Tolerance; Locomotion; Substance-Related Disorders

2013
Effects of methcathinone and 3-Cl-methcathinone (PAL-434) in cocaine discrimination or self-administration in rhesus monkeys.
    The international journal of neuropsychopharmacology, 2013, Volume: 16, Issue:9

    Topics: Animals; Behavior, Addictive; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Discrimination, Psychological; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Eating; Macaca mulatta; Male; Propiophenones; Reinforcement, Psychology; Self Administration; Serotonin; Time Factors

2013
Adolescent atomoxetine treatment in a rodent model of ADHD: effects on cocaine self-administration and dopamine transporters in frontostriatal regions.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2013, Volume: 38, Issue:13

    Topics: Adrenergic Uptake Inhibitors; Animals; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hyperactivity; Cocaine; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Frontal Lobe; Male; Propylamines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reinforcement Schedule; Self Administration

2013
A choice-based screening method for compulsive drug users in rats.
    Current protocols in neuroscience, 2013, Volume: Chapter 9

    Topics: Animals; Choice Behavior; Cocaine; Compulsive Behavior; Conditioning, Operant; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug Administration Routes; Drug-Seeking Behavior; Rats; Rats, Wistar; Reward; Saccharin; Self Administration; Substance Abuse Detection; Sweetening Agents; Time Factors

2013
Neurodegeneration of lateral habenula efferent fibers after intermittent cocaine administration: implications for deep brain stimulation.
    Neuropharmacology, 2013, Volume: 75

    Topics: Animals; Cell Count; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Deep Brain Stimulation; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Efferent Pathways; Extinction, Psychological; Habenula; Male; Nerve Degeneration; Nerve Fibers; Rats; Rats, Sprague-Dawley; Self Administration; Ventral Tegmental Area

2013
Assessing addiction vulnerability with different rat strains and place preference procedures: the role of the cocaine and amphetamine-regulated transcript.
    Behavioural pharmacology, 2013, Volume: 24, Issue:5-6

    Topics: Animals; Cocaine; Conditioning, Operant; Disease Models, Animal; Drug-Seeking Behavior; Gene Expression Regulation; Male; Morphine; Nerve Tissue Proteins; Nucleus Accumbens; Rats; Rats, Inbred F344; Rats, Inbred Lew; Rats, Sprague-Dawley; RNA, Messenger; Species Specificity

2013
Metabolic profiling of urine and blood plasma in rat models of drug addiction on the basis of morphine, methamphetamine, and cocaine-induced conditioned place preference.
    Analytical and bioanalytical chemistry, 2014, Volume: 406, Issue:5

    Topics: Animals; Cocaine; Conditioning, Operant; Disease Models, Animal; Gas Chromatography-Mass Spectrometry; Male; Metabolic Networks and Pathways; Metabolome; Methamphetamine; Morphine; Narcotics; Rats; Rats, Sprague-Dawley; Reward; Substance-Related Disorders

2014
Maturation of silent synapses in amygdala-accumbens projection contributes to incubation of cocaine craving.
    Nature neuroscience, 2013, Volume: 16, Issue:11

    Topics: Amygdala; Animals; Channelrhodopsins; Cocaine; Conditioning, Operant; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Gene Expression Regulation; HEK293 Cells; Humans; Male; Neural Pathways; Nucleus Accumbens; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Self Administration; Spermine; Substance Withdrawal Syndrome; Synapses

2013
Changes in sensitivity of reward and motor behavior to dopaminergic, glutamatergic, and cholinergic drugs in a mouse model of fragile X syndrome.
    PloS one, 2013, Volume: 8, Issue:10

    Topics: Animals; Antipsychotic Agents; Aripiprazole; Behavior, Animal; Blotting, Western; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Fragile X Mental Retardation Protein; Fragile X Syndrome; Immunoenzyme Techniques; Male; Mice; Mice, Knockout; Motor Activity; Muscarinic Antagonists; Piperazines; Pyridines; Quinolones; Receptor, Metabotropic Glutamate 5; Reward; Trihexyphenidyl; Tyrosine 3-Monooxygenase

2013
Maintained cocaine self-administration is determined by quantal responses: implications for the measurement of antagonist potency.
    The Journal of pharmacology and experimental therapeutics, 2014, Volume: 348, Issue:2

    Topics: Administration, Intravenous; Animals; Behavior, Animal; Benzazepines; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Male; Narcotic Antagonists; Narcotics; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Satiety Response; Self Administration; Time Factors

2014
Pretreatment with intravenous lipid emulsion reduces mortality from cocaine toxicity in a rat model.
    Annals of emergency medicine, 2014, Volume: 64, Issue:1

    Topics: Animals; Blood Pressure; Cocaine; Disease Models, Animal; Electrocardiography; Fat Emulsions, Intravenous; Heart Rate; Hemodynamics; Male; Random Allocation; Rats; Rats, Sprague-Dawley; Sodium Chloride; Survival Rate; Time Factors

2014
Selective action of an atypical neuroleptic on the mechanisms related to the development of cocaine addiction: a pre-clinical behavioural study.
    The international journal of neuropsychopharmacology, 2014, Volume: 17, Issue:4

    Topics: Animals; Antipsychotic Agents; Aripiprazole; Behavior, Animal; Central Nervous System Sensitization; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Antagonists; Dopamine Uptake Inhibitors; Haloperidol; Male; Mice; Motor Activity; Piperazines; Quinolones; Thiazoles

2014
Blockade of hypocretin receptor-1 preferentially prevents cocaine seeking: comparison with natural reward seeking.
    Neuroreport, 2014, May-07, Volume: 25, Issue:7

    Topics: Analysis of Variance; Anesthetics, Local; Animals; Benzoxazoles; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Extinction, Psychological; Male; Naphthyridines; Orexin Receptor Antagonists; Orexin Receptors; Rats; Rats, Wistar; Reward; Self Administration; Sweetening Agents; Urea

2014
Dopamine in the dorsal hippocampus impairs the late consolidation of cocaine-associated memory.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2014, Volume: 39, Issue:7

    Topics: Animals; Association Learning; Brain-Derived Neurotrophic Factor; Cocaine; Conditioning, Operant; Disease Models, Animal; Dopamine; Dopamine Agents; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Routes; Hippocampus; Lithium Chloride; Male; MAP Kinase Signaling System; Memory Disorders; Rats; Rats, Sprague-Dawley; Receptor, trkB; Time Factors

2014
Relation between microPET imaging and rotational behavior in a parkinsonian rat model induced by medial forebrain bundle axotomy.
    Behavioural brain research, 2014, May-15, Volume: 265

    Topics: Animals; Apomorphine; Axotomy; Cocaine; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Dopamine Uptake Inhibitors; Functional Laterality; Male; Medial Forebrain Bundle; Parkinson Disease; Raclopride; Radionuclide Imaging; Rats; Rats, Wistar; Stereotyped Behavior; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase

2014
Random-ratio schedules produce greater demand for i.v. drug administration than fixed-ratio schedules in rhesus monkeys.
    Psychopharmacology, 2014, Volume: 231, Issue:15

    Topics: Administration, Intravenous; Analgesics, Opioid; Anesthetics, Dissociative; Animals; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Female; Ketamine; Macaca mulatta; Male; Motivation; Piperidines; Reinforcement Schedule; Remifentanil; Reward; Self Administration; Substance-Related Disorders

2014
Designer receptors show role for ventral pallidum input to ventral tegmental area in cocaine seeking.
    Nature neuroscience, 2014, Volume: 17, Issue:4

    Topics: Animals; Basal Ganglia; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Cues; Disease Models, Animal; Dopaminergic Neurons; Male; Neural Inhibition; Neural Pathways; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Receptors, Dopamine; Recurrence; Reward; Ventral Tegmental Area

2014
Psychiatric disturbances regulate the innate immune system in CSF of conscious mice.
    Translational psychiatry, 2014, Mar-04, Volume: 4

    Topics: Animals; Brain; Cerebrospinal Fluid; Cocaine; Disease Models, Animal; Immunity, Innate; Male; Mental Disorders; Mice; Mice, Inbred C57BL; Signal Transduction; Stress, Psychological

2014
The effects of N-acetylcysteine on cocaine reward and seeking behaviors in a rat model of depression.
    Behavioural brain research, 2014, Jun-01, Volume: 266

    Topics: Acetylcysteine; Animals; Cocaine; Conditioning, Operant; Depression; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Extinction, Psychological; Free Radical Scavengers; Male; Motor Activity; Olfactory Bulb; Rats; Rats, Wistar; Reward; Self Administration

2014
The discovery of Yuanzhi-1, a triterpenoid saponin derived from the traditional Chinese medicine, has antidepressant-like activity.
    Progress in neuro-psychopharmacology & biological psychiatry, 2014, Aug-04, Volume: 53

    Topics: Animals; Antidepressive Agents; Citalopram; Cocaine; Depression; Disease Models, Animal; Female; Fluoxetine; Male; Medicine, Chinese Traditional; Membrane Transport Proteins; Mice; Mice, Inbred ICR; Motor Activity; Protein Binding; Rats; Rats, Sprague-Dawley; Saponins; Swimming; Tritium

2014
Assessment of a proposed "three-criteria" cocaine addiction model for use in reinstatement studies with rats.
    Psychopharmacology, 2014, Volume: 231, Issue:16

    Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Discrimination, Psychological; Disease Models, Animal; Drug-Seeking Behavior; Extinction, Psychological; Male; Motivation; Phenotype; Photic Stimulation; Punishment; Rats; Rats, Sprague-Dawley; Recurrence; Reinforcement Schedule; Self Administration

2014
In vivo measures of nigrostriatal neuronal response to unilateral MPTP treatment.
    Brain research, 2014, Jul-07, Volume: 1571

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Cell Count; Chromatography, High Pressure Liquid; Cocaine; Corpus Striatum; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Functional Laterality; Macaca; Male; Neurons; Parkinsonian Disorders; Positron-Emission Tomography; Protein Binding; Substantia Nigra; Tyrosine 3-Monooxygenase; Vesicular Monoamine Transport Proteins

2014
Contrasting forms of cocaine-evoked plasticity control components of relapse.
    Nature, 2014, May-22, Volume: 509, Issue:7501

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopaminergic Neurons; Drug-Seeking Behavior; Female; Hippocampus; Male; Mice; N-Methylaspartate; Neural Pathways; Neuronal Plasticity; Nucleus Accumbens; Optogenetics; Prefrontal Cortex; Receptors, AMPA; Receptors, Dopamine D1; Recurrence; Synapses

2014
Coordinated Recruitment of Cortical-Subcortical Circuits and Ascending Dopamine and Serotonin Neurons During Inhibitory Control of Cocaine Seeking in Rats.
    Cerebral cortex (New York, N.Y. : 1991), 2015, Volume: 25, Issue:9

    Topics: Afferent Pathways; Animals; Cerebral Cortex; Cocaine; Conditioning, Operant; Corpus Striatum; Discrimination, Psychological; Disease Models, Animal; Dopamine Uptake Inhibitors; Dopaminergic Neurons; Drug-Seeking Behavior; Inhibition, Psychological; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Serotonergic Neurons; Tryptophan Hydroxylase; Tyrosine 3-Monooxygenase

2015
Dynamics of cocaine- and amphetamine-regulated transcript containing cell changes in the adrenal glands of two kidney, one clip rats.
    Experimental biology and medicine (Maywood, N.J.), 2014, Volume: 239, Issue:10

    Topics: Adrenal Glands; Amphetamine; Animals; Cocaine; Disease Models, Animal; Gene Expression Profiling; Hypertension, Renovascular; Immunohistochemistry; Male; Nerve Tissue Proteins; Rats, Wistar; Sympathomimetics; Time Factors; Vasoconstrictor Agents

2014
Acid-sensing ion channels contribute to synaptic transmission and inhibit cocaine-evoked plasticity.
    Nature neuroscience, 2014, Volume: 17, Issue:8

    Topics: Acid Sensing Ion Channels; Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Excitatory Postsynaptic Potentials; Female; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Neural Inhibition; Neuronal Plasticity; Nucleus Accumbens; Rats; Synaptic Transmission; Up-Regulation

2014
Orbitofrontal activation restores insight lost after cocaine use.
    Nature neuroscience, 2014, Volume: 17, Issue:8

    Topics: Animals; Awareness; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Learning; Male; Optogenetics; Prefrontal Cortex; Rats; Rats, Long-Evans; Self Administration; Synapses

2014
Economic demand predicts addiction-like behavior and therapeutic efficacy of oxytocin in the rat.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Aug-12, Volume: 111, Issue:32

    Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Drug-Seeking Behavior; Humans; Male; Models, Economic; Motivation; Oxytocin; Rats; Rats, Sprague-Dawley; Self Administration

2014
Synapse density and dendritic complexity are reduced in the prefrontal cortex following seven days of forced abstinence from cocaine self-administration.
    PloS one, 2014, Volume: 9, Issue:7

    Topics: Animals; Brain-Derived Neurotrophic Factor; Cocaine; Cocaine-Related Disorders; Dendrites; Disease Models, Animal; Male; Prefrontal Cortex; Rats; Synapses; Time Factors

2014
Cognitive judgment bias in the psychostimulant-induced model of mania in rats.
    Psychopharmacology, 2015, Volume: 232, Issue:3

    Topics: Animals; Behavior, Animal; Bipolar Disorder; Cocaine; Dextroamphetamine; Disease Models, Animal; Dopamine Uptake Inhibitors; Judgment; Male; Rats; Rats, Sprague-Dawley

2015
A human recombinant monoclonal antibody to cocaine: Preparation, characterization and behavioral studies.
    Bioorganic & medicinal chemistry letters, 2014, Oct-01, Volume: 24, Issue:19

    Topics: Animals; Antibodies, Monoclonal; Ataxia; Cocaine; Disease Models, Animal; Humans; Immunotherapy; Mice; Molecular Conformation; Recombinant Proteins

2014
Effects of the combination of wheel running and atomoxetine on cue- and cocaine-primed reinstatement in rats selected for high or low impulsivity.
    Psychopharmacology, 2015, Volume: 232, Issue:6

    Topics: Animals; Atomoxetine Hydrochloride; Cocaine; Cocaine-Related Disorders; Cues; Disease Models, Animal; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Extinction, Psychological; Female; Impulsive Behavior; Motor Activity; Physical Conditioning, Animal; Propylamines; Rats; Rats, Wistar; Running; Self Administration

2015
Analysis of opioid-seeking reinstatement in the rat.
    Methods in molecular biology (Clifton, N.J.), 2015, Volume: 1230

    Topics: Analgesics, Opioid; Animals; Behavior, Addictive; Cocaine; Conditioning, Operant; Disease Models, Animal; Heroin; Humans; Opioid-Related Disorders; Rats; Receptors, Opioid; Substance-Related Disorders

2015
Cocaine-induced suppression of saccharin intake and morphine modulation of Ca²⁺ channel currents in sensory neurons of OPRM1 A118G mice.
    Physiology & behavior, 2015, Volume: 139

    Topics: Animals; Behavior, Addictive; Calcium Channels; Cells, Cultured; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Eating; Humans; Male; Mice, Transgenic; Polymorphism, Single Nucleotide; Receptors, Opioid, mu; Reward; Saccharin; Sensory Receptor Cells; Substance Withdrawal Syndrome; Trigeminal Ganglion

2015
Region-specific effects of isoflurane anesthesia on Fos immunoreactivity in response to intravenous cocaine challenge in rats with a history of repeated cocaine administration.
    Brain research, 2015, Jan-12, Volume: 1594

    Topics: Anesthetics, Inhalation; Animals; Brain; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Immunohistochemistry; Isoflurane; Male; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley

2015
Pharmacological inactivation of the prelimbic cortex emulates compulsive reward seeking in rats.
    Brain research, 2015, Dec-02, Volume: 1628, Issue:Pt A

    Topics: Animals; Baclofen; Cerebral Cortex; Cocaine; Cocaine-Related Disorders; Decision Making; Dietary Sucrose; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Executive Function; GABA Agonists; Goals; Impulsive Behavior; Male; Muscimol; Rats, Wistar; Reward

2015
Chronic stimulation of the tone of endogenous anandamide reduces cue- and stress-induced relapse in rats.
    The international journal of neuropsychopharmacology, 2014, Dec-05, Volume: 18, Issue:1

    Topics: Amidohydrolases; Animals; Arachidonic Acids; Benzamides; Carbamates; Cocaine; Cocaine-Related Disorders; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Endocannabinoids; Enzyme Inhibitors; Male; Polyunsaturated Alkamides; Rats, Sprague-Dawley; Recurrence; Self Administration; Stress, Physiological; Yohimbine

2014
Prenatal exposure to methylphenidate affects the dopamine system and the reactivity to natural reward in adulthood in rats.
    The international journal of neuropsychopharmacology, 2014, Oct-31, Volume: 18, Issue:4

    Topics: Animals; Brain; Central Nervous System Stimulants; Cocaine; Dietary Sucrose; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Female; Male; Methylphenidate; Motivation; Motor Activity; Pregnancy; Prenatal Exposure Delayed Effects; Random Allocation; Rats; Rats, Wistar; Reward

2014
A single brain-derived neurotrophic factor infusion into the dorsomedial prefrontal cortex attenuates cocaine self-administration-induced phosphorylation of synapsin in the nucleus accumbens during early withdrawal.
    The international journal of neuropsychopharmacology, 2014, Dec-05, Volume: 18, Issue:1

    Topics: Animals; Brain-Derived Neurotrophic Factor; Central Nervous System Agents; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Male; Nucleus Accumbens; Phosphorylation; Prefrontal Cortex; Rats, Sprague-Dawley; Self Administration; Substance Withdrawal Syndrome; Synapsins

2014
Loss of feedback inhibition via D2 autoreceptors enhances acquisition of cocaine taking and reactivity to drug-paired cues.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2015, Volume: 40, Issue:6

    Topics: Animals; Autoreceptors; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Feedback, Physiological; Male; Mesencephalon; Mice, Knockout; Neural Inhibition; Neurons; Receptors, Dopamine D2; Self Administration

2015
Didehydro-cortistatin A inhibits HIV-1 Tat mediated neuroinflammation and prevents potentiation of cocaine reward in Tat transgenic mice.
    Current HIV research, 2015, Volume: 13, Issue:1

    Topics: Animals; Anti-HIV Agents; Chemokines; Cocaine; Cytokines; Disease Models, Animal; Dopamine Uptake Inhibitors; Heterocyclic Compounds, 4 or More Rings; HIV Infections; HIV-1; Inflammation; Isoquinolines; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurocognitive Disorders; Reward; tat Gene Products, Human Immunodeficiency Virus

2015
Dorsal raphe 5-HT(2C) receptor and GABA networks regulate anxiety produced by cocaine withdrawal.
    Neuropharmacology, 2015, Volume: 93

    Topics: Action Potentials; Animals; Anxiety; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Dorsal Raphe Nucleus; Exploratory Behavior; gamma-Aminobutyric Acid; Inhibitory Postsynaptic Potentials; Male; Maze Learning; Mice; Mice, Inbred C57BL; Neurons; Patch-Clamp Techniques; Receptor, Serotonin, 5-HT2C; Serotonin Agents; Substance Withdrawal Syndrome; Time Factors; Tryptophan Hydroxylase

2015
Functional consequences of cocaine expectation: findings in a non-human primate model of cocaine self-administration.
    Addiction biology, 2016, Volume: 21, Issue:3

    Topics: Animals; Autoradiography; Behavior, Animal; Brain; Carbon Radioisotopes; Cocaine; Cocaine-Related Disorders; Cues; Deoxyglucose; Disease Models, Animal; Dopamine Uptake Inhibitors; Macaca mulatta; Male; Neostriatum; Prefrontal Cortex; Reinforcement Schedule; Reinforcement, Psychology; Self Administration; Spectrophotometry; Temporal Lobe; Thalamus

2016
Single prolonged stress effects on sensitization to cocaine and cocaine self-administration in rats.
    Behavioural brain research, 2015, May-01, Volume: 284

    Topics: Akathisia, Drug-Induced; Animals; Catheters, Indwelling; Cocaine; Cocaine-Related Disorders; Cohort Studies; Conditioning, Operant; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Extinction, Psychological; Male; Rats, Sprague-Dawley; Self Administration; Stress, Psychological

2015
Enhanced Cocaine-Associated Contextual Learning in Female H/Rouen Mice Selectively Bred for Depressive-Like Behaviors: Molecular and Neuronal Correlates.
    The international journal of neuropsychopharmacology, 2015, Mar-02, Volume: 18, Issue:8

    Topics: Akathisia, Drug-Induced; Animals; Brain; Brain-Derived Neurotrophic Factor; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Depressive Disorder; Disease Models, Animal; Dopamine Uptake Inhibitors; Female; Male; Memory; Mice; Motor Activity; Proto-Oncogene Proteins c-fos; Sex Characteristics; Spatial Behavior; Time Factors

2015
Corn oil, but not cocaine, is a more effective reinforcer in obese than in lean Zucker rats.
    Physiology & behavior, 2015, May-01, Volume: 143

    Topics: Animals; Cocaine; Conditioning, Operant; Corn Oil; Disease Models, Animal; Dopamine Uptake Inhibitors; Food Preferences; Male; Obesity; Rats; Rats, Zucker; Reinforcement Schedule; Reinforcement, Psychology; Self Administration; Statistics, Nonparametric

2015
Increased Sensitivity to Cocaine Self-Administration in HIV-1 Transgenic Rats is Associated with Changes in Striatal Dopamine Transporter Binding.
    Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 2015, Volume: 10, Issue:3

    Topics: Animals; Behavior, Animal; Cocaine; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Heroin; HIV Infections; Male; Narcotics; Neostriatum; Protein Binding; Rats; Rats, Inbred F344; Rats, Transgenic; Self Administration

2015
Persistent conditioned place preference to cocaine and withdrawal hypo-locomotion to mephedrone in the flatworm planaria.
    Neuroscience letters, 2015, Apr-23, Volume: 593

    Topics: Animals; Cocaine; Conditioning, Psychological; Disease Models, Animal; Locomotion; Methamphetamine; Planarians; Psychotropic Drugs; Substance Withdrawal Syndrome; Substance-Related Disorders

2015
Evidence for a role for α6(∗) nAChRs in l-dopa-induced dyskinesias using Parkinsonian α6(∗) nAChR gain-of-function mice.
    Neuroscience, 2015, Jun-04, Volume: 295

    Topics: Adrenergic Agents; Analysis of Variance; Animals; Antiparkinson Agents; Benserazide; Cocaine; Disease Models, Animal; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Levodopa; Male; Mice; Mice, Transgenic; Nicotine; Nicotinic Agonists; Oxidopamine; Parkinsonian Disorders; Protein Binding; Receptors, Nicotinic

2015
Gq-DREADD Selectively Initiates Glial Glutamate Release and Inhibits Cue-induced Cocaine Seeking.
    Biological psychiatry, 2015, Oct-01, Volume: 78, Issue:7

    Topics: Animals; Astrocytes; Calcium Channels, N-Type; Central Nervous System Agents; Clozapine; Cocaine; Cocaine-Related Disorders; Cues; Dietary Sucrose; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Extinction, Psychological; Genetic Therapy; Glutamic Acid; Male; Mice, Transgenic; Nucleus Accumbens; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Receptors, Metabotropic Glutamate; Self Administration; SNARE Proteins

2015
Enhanced anxiety in the male offspring of sires that self-administered cocaine.
    Addiction biology, 2016, Volume: 21, Issue:4

    Topics: Animals; Anxiety; Behavior, Animal; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Fathers; Female; Male; Paternal Exposure; Pregnancy; Rats; Rats, Sprague-Dawley; Sex Factors

2016
The effects of a shared history of drug exposure on social choice.
    Behavioural pharmacology, 2015, Volume: 26, Issue:7 Spec No

    Topics: Animals; Choice Behavior; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Disease Models, Animal; Dopamine Uptake Inhibitors; Male; Psychological Tests; Rats, Long-Evans; Social Behavior

2015
Development of translational preclinical models in substance abuse: Effects of cocaine administration on cocaine choice in humans and non-human primates.
    Pharmacology, biochemistry, and behavior, 2015, Volume: 134

    Topics: Adult; Animals; Choice Behavior; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Female; Humans; Macaca mulatta; Male; Middle Aged; Placebos; Self Administration; Translational Research, Biomedical

2015
Blocking Infralimbic Basic Fibroblast Growth Factor (bFGF or FGF2) Facilitates Extinction of Drug Seeking After Cocaine Self-Administration.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2015, Volume: 40, Issue:13

    Topics: Animals; Central Nervous System Agents; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Extinction, Psychological; Fibroblast Growth Factor 2; Male; Prefrontal Cortex; Rats, Long-Evans; Self Administration

2015
A therapeutic combination of metyrapone and oxazepam increases brain levels of GABA-active neurosteroids and decreases cocaine self-administration in male rats.
    Behavioural brain research, 2015, Sep-15, Volume: 291

    Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Desoxycorticosterone; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; GABA Modulators; Male; Metyrapone; Motivation; Oxazepam; Pregnanolone; Rats, Wistar; Self Administration

2015
Short-term withdrawal from developmental exposure to cocaine activates the glucocorticoid receptor and alters spine dynamics.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2015, Volume: 25, Issue:10

    Topics: Animals; Cocaine; Corticosterone; Dendritic Spines; Disease Models, Animal; Dopamine Uptake Inhibitors; Male; Prefrontal Cortex; Rats, Sprague-Dawley; Receptors, Glucocorticoid; RNA, Messenger; Substance Withdrawal Syndrome; Tacrolimus Binding Proteins; Time Factors

2015
Microglia disrupt mesolimbic reward circuitry in chronic pain.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015, Jun-03, Volume: 35, Issue:22

    Topics: Animals; Area Under Curve; Chronic Pain; Cocaine; Conditioning, Classical; Disease Models, Animal; Glutamate Decarboxylase; Hyperalgesia; Limbic System; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Minocycline; Morphine; Nerve Net; Nucleus Accumbens; Pain Threshold; Rats; Rats, Sprague-Dawley; Reward; Sciatic Neuropathy; Ventral Tegmental Area

2015
Response of the Ubiquitin-Proteasome System to Memory Retrieval After Extended-Access Cocaine or Saline Self-Administration.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2015, Volume: 40, Issue:13

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Craving; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Male; Memory; Nucleus Accumbens; Proteasome Endopeptidase Complex; Rats, Sprague-Dawley; Self Administration; Substance Withdrawal Syndrome; Ubiquitin

2015
Hypocretin receptor 1 blockade preferentially reduces high effort responding for cocaine without promoting sleep.
    Behavioural brain research, 2015, Sep-15, Volume: 291

    Topics: Animals; Appetitive Behavior; Benzoxazoles; Brain; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Hypnotics and Sedatives; Male; Naphthyridines; Orexin Receptor Antagonists; Orexin Receptors; Rats, Sprague-Dawley; Reinforcement Schedule; Self Administration; Sleep; Urea

2015
Effects of prenatal immune activation on amphetamine-induced addictive behaviors: Contributions from animal models.
    Progress in neuro-psychopharmacology & biological psychiatry, 2015, Dec-03, Volume: 63

    Topics: Amphetamine-Related Disorders; Animals; Cocaine; Conditioning, Psychological; Disease Models, Animal; Exploratory Behavior; Female; Male; Mice; Motor Activity; Poly I-C; Pregnancy; Prenatal Exposure Delayed Effects; Stereotyped Behavior; Time Factors

2015
Methyl supplementation attenuates cocaine-seeking behaviors and cocaine-induced c-Fos activation in a DNA methylation-dependent manner.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015, Jun-10, Volume: 35, Issue:23

    Topics: Animals; Body Weight; Brain; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Disease Models, Animal; DNA Methylation; DNA Methyltransferase 3A; Dopamine Uptake Inhibitors; Drinking; Drug-Seeking Behavior; Eating; Extinction, Psychological; Male; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration; Sucrose; Sweetening Agents

2015
Cocaine-mediated impact on HIV infection in humanized BLT mice.
    Scientific reports, 2015, Jun-18, Volume: 5

    Topics: Animals; CD8-Positive T-Lymphocytes; Cocaine; Cytokines; Disease Models, Animal; Gene Expression Regulation; HIV Infections; HIV-1; Humans; Mice

2015
Effects of chronic cocaine treatment during adolescence in Lewis and Fischer-344 rats: Novel location recognition impairment and changes in synaptic plasticity in adulthood.
    Neurobiology of learning and memory, 2015, Volume: 123

    Topics: Age Factors; Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Hippocampus; Male; Memory Disorders; Neuronal Plasticity; Rats; Rats, Inbred F344; Rats, Inbred Lew; Receptors, N-Methyl-D-Aspartate; Recognition, Psychology; Spatial Memory

2015
Anhedonia, Reduced Cocaine Reward, and Dopamine Dysfunction in a Rat Model of Posttraumatic Stress Disorder.
    Biological psychiatry, 2015, Dec-15, Volume: 78, Issue:12

    Topics: Anhedonia; Animals; Behavior, Animal; Cocaine; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Male; Neostriatum; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Reward; Self Administration; Stress Disorders, Post-Traumatic

2015
A Critical Role for the GluA1 Accessory Protein, SAP97, in Cocaine Seeking.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2016, Volume: 41, Issue:3

    Topics: Adaptor Proteins, Signal Transducing; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Corpus Striatum; Dietary Sucrose; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Male; Membrane Proteins; Nucleus Accumbens; Rats, Sprague-Dawley; Receptors, AMPA; Self Administration; Tissue Culture Techniques

2016
Enhancing glutamatergic transmission during adolescence reverses early-life stress-induced deficits in the rewarding effects of cocaine in rats.
    Neuropharmacology, 2015, Volume: 99

    Topics: Administration, Intravenous; Aging; Amino Acid Transport System X-AG; Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Maternal Deprivation; Memantine; Rats; Receptors, N-Methyl-D-Aspartate; Reward; Riluzole; Self Administration; Stress, Psychological

2015
Memory of a drug lapse: Role of noradrenaline.
    Neuropharmacology, 2015, Volume: 99

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Animals; Basolateral Nuclear Complex; Clonidine; Cocaine; Conditioning, Psychological; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Heroin; Locus Coeruleus; Male; Memory; Narcotics; Norepinephrine; Prazosin; Propranolol; Rats, Sprague-Dawley; Spatial Behavior; Substance-Related Disorders

2015
Adolescent-onset of cocaine use is associated with heightened stress-induced reinstatement of cocaine seeking.
    Addiction biology, 2016, Volume: 21, Issue:3

    Topics: Age of Onset; Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Corticosterone; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Electric Stimulation; Extinction, Psychological; Male; Rats; Rats, Sprague-Dawley; Recurrence; Reinforcement, Psychology; Stress, Psychological; Yohimbine

2016
Hippocampal cell fate regulation by chronic cocaine during periods of adolescent vulnerability: Consequences of cocaine exposure during adolescence on behavioral despair in adulthood.
    Neuroscience, 2015, Sep-24, Volume: 304

    Topics: Animals; Cell Proliferation; Cocaine; Cocaine-Related Disorders; Depression; Disease Models, Animal; Dopamine Uptake Inhibitors; Fas-Associated Death Domain Protein; Hippocampus; Male; Neuronal Plasticity; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Rats, Sprague-Dawley

2015
Neuroprotective Effect of Progesterone in MPTP-Treated Male Mice.
    Neuroendocrinology, 2016, Volume: 103, Issue:3-4

    Topics: Androstane-3,17-diol; Animals; Autoradiography; Brain; Carbon Radioisotopes; Cocaine; Dihydrotestosterone; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Drug Administration Schedule; Male; Mice; Mice, Inbred C57BL; MPTP Poisoning; Neuroprotective Agents; Progesterone; Testosterone; Vesicular Monoamine Transport Proteins

2016
A Method for Psychosocial Stress-Induced Reinstatement of Cocaine Seeking in Rats.
    Biological psychiatry, 2016, 06-01, Volume: 79, Issue:11

    Topics: Adaptation, Psychological; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Corticosterone; Disease Models, Animal; Dominance-Subordination; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Extinction, Psychological; Male; Rats, Long-Evans; Recurrence; Self Administration; Stress, Psychological

2016
Cannabidiol, a Cannabis sativa constituent, inhibits cocaine-induced seizures in mice: Possible role of the mTOR pathway and reduction in glutamate release.
    Neurotoxicology, 2015, Volume: 50

    Topics: Anesthetics, Local; Animals; Antiemetics; Cannabidiol; Cocaine; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamic Acid; Immunosuppressive Agents; Indoles; Male; Mice; Seizures; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases

2015
Cocaine-induced reward enhancement measured with intracranial self-stimulation in rats bred for low versus high saccharin intake.
    Behavioural pharmacology, 2016, Volume: 27, Issue:2-3 Spec I

    Topics: Analysis of Variance; Animals; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Electric Stimulation; Food Preferences; Male; Rats; Reward; Saccharin; Self Stimulation; Substance-Related Disorders; Sweetening Agents

2016
The brain disease model of addiction: challenging or reinforcing stigma?
    The lancet. Psychiatry, 2015, Volume: 2, Issue:4

    Topics: Behavior, Addictive; Brain; Brain Diseases; Cocaine; Disease Models, Animal; Humans; Motivation; Reinforcement, Psychology; Social Stigma; Stereotyping; Substance-Related Disorders

2015
Abnormal context-reward associations in an immune-mediated neurodevelopmental mouse model with relevance to schizophrenia.
    Translational psychiatry, 2015, Sep-15, Volume: 5

    Topics: Animals; Cocaine; Conditioning, Psychological; Disease Models, Animal; Fear; Female; Mice; Mice, Inbred C57BL; Neurodevelopmental Disorders; Poly I-C; Pregnancy; Prenatal Exposure Delayed Effects; Reward; Schizophrenia; Sucrose

2015
Effect of cocaine on striatal dopamine clearance in a rat model of developmental stress and attention-deficit/hyperactivity disorder.
    Stress (Amsterdam, Netherlands), 2016, Volume: 19, Issue:1

    Topics: Animals; Attention; Attention Deficit Disorder with Hyperactivity; Cocaine; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Male; Maternal Deprivation; Neostriatum; Rats; Rats, Inbred SHR; Rats, Inbred WKY

2016
Trait and state binge eating predispose towards cocaine craving.
    Addiction biology, 2017, Volume: 22, Issue:1

    Topics: Animals; Behavior, Addictive; Behavior, Animal; Binge-Eating Disorder; Cocaine; Craving; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Male; Rats; Rats, Long-Evans

2017
Adolescent D-amphetamine treatment in a rodent model of ADHD: Pro-cognitive effects in adolescence without an impact on cocaine cue reactivity in adulthood.
    Behavioural brain research, 2016, Jan-15, Volume: 297

    Topics: Aging; Amphetamine; Animals; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Choice Behavior; Cocaine; Cocaine-Related Disorders; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Male; Psychotropic Drugs; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar; Self Administration

2016
Modulation by Trace Amine-Associated Receptor 1 of Experimental Parkinsonism, L-DOPA Responsivity, and Glutamatergic Neurotransmission.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015, Oct-14, Volume: 35, Issue:41

    Topics: Adrenergic Agents; Akathisia, Drug-Induced; Animals; Antiparkinson Agents; Cocaine; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Plasma Membrane Transport Proteins; Glutamic Acid; Levodopa; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oligodeoxyribonucleotides, Antisense; Oxidopamine; Parkinsonian Disorders; Radiopharmaceuticals; Receptors, G-Protein-Coupled; Stereotyped Behavior; Synaptic Transmission; Time Factors; Tyrosine 3-Monooxygenase

2015
HIV-1 transgenic rats display an increase in [(3)H]dopamine uptake in the prefrontal cortex and striatum.
    Journal of neurovirology, 2016, Volume: 22, Issue:3

    Topics: AIDS Dementia Complex; Animals; Cocaine; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Gene Expression; HIV-1; Kinetics; Male; Prefrontal Cortex; Rats; Rats, Inbred F344; Rats, Transgenic; Synaptosomes; tat Gene Products, Human Immunodeficiency Virus; Tritium

2016
Long Withdrawal of Methylphenidate Induces a Differential Response of the Dopaminergic System and Increases Sensitivity to Cocaine in the Prefrontal Cortex of Spontaneously Hypertensive Rats.
    PloS one, 2015, Volume: 10, Issue:10

    Topics: Animals; Attention Deficit Disorder with Hyperactivity; Biological Transport; Central Nervous System Stimulants; Cocaine; Cyclic AMP; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Male; Methylphenidate; Prefrontal Cortex; Rats; Rats, Inbred SHR; Receptors, Dopamine D1

2015
Cocaine-conditioned place preference is predicted by previous anxiety-like behavior and is related to an increased number of neurons in the basolateral amygdala.
    Behavioural brain research, 2016, Feb-01, Volume: 298, Issue:Pt B

    Topics: Animals; Anxiety; Basolateral Nuclear Complex; Cell Count; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Disease Models, Animal; Dopamine Uptake Inhibitors; Immunohistochemistry; Male; Mice, Inbred C57BL; Neurons; Prognosis; Spatial Behavior

2016
Sufficiency of Mesolimbic Dopamine Neuron Stimulation for the Progression to Addiction.
    Neuron, 2015, Dec-02, Volume: 88, Issue:5

    Topics: Animals; Channelrhodopsins; Clozapine; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dopaminergic Neurons; Food Deprivation; GABA Antagonists; Glutamate Decarboxylase; Limbic System; Mice; Mice, Inbred C57BL; Mice, Transgenic; Receptors, Dopamine D1; Self Administration; Sucrose; Synaptic Transmission; Time Factors

2015
Adolescent exposure to cocaine increases anxiety-like behavior and induces morphologic and neurochemical changes in the hippocampus of adult rats.
    Neuroscience, 2016, Jan-28, Volume: 313

    Topics: Animals; Anxiety Disorders; Apoptosis; Astrocytes; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Exploratory Behavior; Hippocampus; Male; Maze Learning; Neuroimmunomodulation; Oxidative Stress; Pyramidal Cells; Rats, Sprague-Dawley; Spatial Memory; Synaptic Transmission

2016
Ventral Subiculum Stimulation Promotes Persistent Hyperactivity of Dopamine Neurons and Facilitates Behavioral Effects of Cocaine.
    Cell reports, 2015, Dec-15, Volume: 13, Issue:10

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Dopaminergic Neurons; Electric Stimulation; Hippocampus; Immunohistochemistry; Motor Activity; Neural Pathways; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Synaptic Transmission

2015
Effects of cocaine history on postsynaptic GABA receptors on dorsal raphe serotonin neurons in a stress-induced relapse model in rats.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2016, Volume: 26, Issue:1

    Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics, Opioid; Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Dorsal Raphe Nucleus; Extinction, Psychological; Inhibitory Postsynaptic Potentials; Male; Morphine; Patch-Clamp Techniques; Rats, Sprague-Dawley; Receptors, GABA; Self Administration; Serotonergic Neurons; Stress, Psychological; Tissue Culture Techniques; Yohimbine

2016
Cocaine craving during protracted withdrawal requires PKCε priming within vmPFC.
    Addiction biology, 2017, Volume: 22, Issue:3

    Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Craving; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Immunoblotting; Male; Prefrontal Cortex; Protein Kinase C-epsilon; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome

2017
Strain and cocaine-induced differential opioid gene expression may predispose Lewis but not Fischer rats to escalate cocaine self-administration.
    Neuropharmacology, 2016, Volume: 105

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Disease Models, Animal; Gene Expression; Genetic Predisposition to Disease; Male; Nucleus Accumbens; Opioid Peptides; Rats, Inbred F344; Rats, Inbred Lew; Receptors, Opioid; RNA, Messenger; Self Administration; Species Specificity; Vasoconstrictor Agents

2016
Naloxone injections into CA3 disrupt pattern completion associated with relapse from cocaine seeking.
    Hippocampus, 2016, Volume: 26, Issue:7

    Topics: Animals; CA3 Region, Hippocampal; Central Nervous System Agents; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Male; Naloxone; Rats, Long-Evans; Recurrence; Spatial Behavior

2016
Cannabidiol disrupts the reconsolidation of contextual drug-associated memories in Wistar rats.
    Addiction biology, 2017, Volume: 22, Issue:3

    Topics: Animals; Cannabidiol; Cocaine; Conditioning, Classical; Cues; Disease Models, Animal; Male; Memory; Mental Recall; Morphine; Naltrexone; Rats; Rats, Wistar; Reward

2017
Expression of functional cannabinoid CB
    Addiction biology, 2017, Volume: 22, Issue:3

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopaminergic Neurons; Immunohistochemistry; Male; Rats; Rats, Long-Evans; Real-Time Polymerase Chain Reaction; Receptor, Cannabinoid, CB2; Ventral Tegmental Area

2017
Abstinence from cocaine-self-administration activates the nELAV/GAP -43 pathway in the hippocampus: A stress-related effect?
    Hippocampus, 2016, Volume: 26, Issue:6

    Topics: Animals; Blotting, Western; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; ELAV-Like Protein 1; GAP-43 Protein; Hippocampus; Rats; Self Administration; Signal Transduction; Stress, Psychological; Substance Withdrawal Syndrome

2016
Perseveration of craving: effects of stimuli conditioned to drugs of abuse versus conventional reinforcers differing in demand.
    Addiction biology, 2017, Volume: 22, Issue:4

    Topics: Animals; Behavior, Animal; Cocaine; Conditioning, Classical; Craving; Cues; Dietary Sugars; Disease Models, Animal; Ethanol; Male; Motivation; Rats; Rats, Wistar; Reinforcement, Psychology; Reward; Self Administration; Water

2017
Social threat exposure in juvenile mice promotes cocaine-seeking by altering blood clotting and brain vasculature.
    Addiction biology, 2017, Volume: 22, Issue:4

    Topics: Animals; Behavior, Animal; Blood Coagulation; Brain; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Male; Mice; Mice, Inbred DBA; Social Behavior; Stress, Psychological

2017
Differential antagonism and tolerance/cross-tolerance among nicotinic acetylcholine receptor agonists: scheduled-controlled responding and hypothermia in C57BL/6J mice.
    Behavioural pharmacology, 2016, Volume: 27, Issue:2-3 Spec I

    Topics: Animals; Cocaine; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Tolerance; Hyperthermia, Induced; Male; Mecamylamine; Mice; Mice, Inbred C57BL; Nicotinic Agonists; Nicotinic Antagonists; Reinforcement Schedule; Tobacco Use Disorder

2016
Inhibiting subthalamic nucleus decreases cocaine demand and relapse: therapeutic potential.
    Addiction biology, 2017, Volume: 22, Issue:4

    Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Male; Rats; Rats, Sprague-Dawley; Recurrence; Subthalamic Nucleus

2017
Role of Dopamine 2 Receptor in Impaired Drug-Cue Extinction in Adolescent Rats.
    Cerebral cortex (New York, N.Y. : 1991), 2016, Volume: 26, Issue:6

    Topics: Animals; Antipsychotic Agents; Aripiprazole; Cocaine; Cocaine-Related Disorders; Cues; Disease Models, Animal; Dopamine Agonists; Dopamine Uptake Inhibitors; Extinction, Psychological; Learning; Male; Motivation; Prefrontal Cortex; Quinpirole; Random Allocation; Rats, Sprague-Dawley; Receptors, Dopamine D2; Self Administration

2016
Assessment of Cocaine-induced Behavioral Sensitization and Conditioned Place Preference in Mice.
    Journal of visualized experiments : JoVE, 2016, Feb-18, Issue:108

    Topics: Analysis of Variance; Animals; Behavior, Animal; Central Nervous System Sensitization; Cocaine; Conditioning, Psychological; Disease Models, Animal; Drug-Seeking Behavior; Mice; Mice, Inbred C57BL; Neuronal Plasticity; Reward; Substance-Related Disorders

2016
Risk-preferring rats make worse decisions and show increased incubation of craving after cocaine self-administration.
    Addiction biology, 2017, Volume: 22, Issue:4

    Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Craving; Decision Making; Disease Models, Animal; Dopamine Uptake Inhibitors; Male; Rats; Rats, Long-Evans; Risk; Self Administration

2017
Unaltered cocaine self-administration in the prenatal LPS rat model of schizophrenia.
    Progress in neuro-psychopharmacology & biological psychiatry, 2016, 08-01, Volume: 69

    Topics: Animals; Auditory Perception; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Female; Lipopolysaccharides; Male; Maze Learning; Memory Disorders; Memory, Short-Term; Pregnancy; Prenatal Exposure Delayed Effects; Prepulse Inhibition; Rats, Sprague-Dawley; Reflex, Startle; Schizophrenia; Schizophrenic Psychology; Self Administration; Sex Characteristics

2016
Exercise during early, but not late abstinence, attenuates subsequent relapse vulnerability in a rat model.
    Translational psychiatry, 2016, Apr-26, Volume: 6

    Topics: Animals; Behavior, Addictive; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Male; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley; Recurrence; Time Factors

2016
Intravenous lipid emulsion in the resuscitation of cocaine-induced cardiovascular arrest in a rat model.
    The American journal of emergency medicine, 2016, Volume: 34, Issue:8

    Topics: Animals; Cocaine; Disease Models, Animal; Fat Emulsions, Intravenous; Heart Arrest; Male; Rats; Rats, Sprague-Dawley; Resuscitation

2016
Pharmacological modulation of lateral habenular dopamine D2 receptors alters the anxiogenic response to cocaine in a runway model of drug self-administration.
    Behavioural brain research, 2016, 09-01, Volume: 310

    Topics: Animals; Anxiety; Benzimidazoles; Catheters, Indwelling; Cocaine; Cocaine-Related Disorders; Conflict, Psychological; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Dopamine Uptake Inhibitors; Flupenthixol; Habenula; Male; Motor Activity; Rats, Sprague-Dawley; Receptors, Dopamine D2; Self Administration

2016
`Up-regulation of histone acetylation induced by social defeat mediates the conditioned rewarding effects of cocaine.
    Progress in neuro-psychopharmacology & biological psychiatry, 2016, 10-03, Volume: 70

    Topics: Acetylation; Animals; Central Nervous System Stimulants; Cerebral Cortex; Cocaine; Conditioning, Psychological; Disease Models, Animal; Dominance-Subordination; Epigenesis, Genetic; Hippocampus; Histone Acetyltransferases; Histone Deacetylase Inhibitors; Histones; Male; Mice; Reward; Spatial Behavior; Stress, Psychological; Up-Regulation; Valproic Acid

2016
Conditioned stress prevents cue-primed cocaine reinstatement only in stress-responsive rats.
    Stress (Amsterdam, Netherlands), 2016, Volume: 19, Issue:4

    Topics: Amygdala; Animals; Cocaine; Cocaine-Related Disorders; Corticosterone; Corticotropin-Releasing Hormone; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Extinction, Psychological; Hippocampus; Male; Rats; Rats, Sprague-Dawley; Reflex, Startle; Self Administration; Stress, Psychological

2016
CRF type 1 receptor antagonism in ventral tegmental area of adolescent rats during social defeat: prevention of escalated cocaine self-administration in adulthood and behavioral adaptations during adolescence.
    Psychopharmacology, 2016, Volume: 233, Issue:14

    Topics: Adaptation, Psychological; Aminopyridines; Animals; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Corticotropin-Releasing Hormone; Disease Models, Animal; Locomotion; Male; Rats; Rats, Long-Evans; Receptors, Corticotropin-Releasing Hormone; Reinforcement, Psychology; Self Administration; Social Behavior; Stress, Psychological; Ventral Tegmental Area

2016
Responses to drugs of abuse and non-drug rewards in leptin deficient ob/ob mice.
    Psychopharmacology, 2016, Volume: 233, Issue:14

    Topics: Amphetamine; Animals; Behavior, Animal; Central Nervous System Depressants; Cocaine; Conditioning, Operant; Disease Models, Animal; Dopamine Uptake Inhibitors; Ethanol; Exploratory Behavior; Feeding Behavior; Illicit Drugs; Leptin; Locomotion; Male; Mice; Motor Activity; Piperidines; Remifentanil; Taste

2016
Extended cocaine-seeking produces a shift from goal-directed to habitual responding in rats.
    Physiology & behavior, 2016, 10-01, Volume: 164, Issue:Pt A

    Topics: Analysis of Variance; Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Extinction, Psychological; Goals; Habits; Lithium Chloride; Male; Rats, Sprague-Dawley; Self Administration; Time Factors

2016
The Naturally Occurring Compound Garcinia Indica Selectively Impairs the Reconsolidation of a Cocaine-Associated Memory.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2017, Volume: 42, Issue:3

    Topics: Animals; Association Learning; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Garcinia; Male; Memory Consolidation; Rats, Sprague-Dawley; Terpenes

2017
Eating 'Junk-Food' Produces Rapid and Long-Lasting Increases in NAc CP-AMPA Receptors: Implications for Enhanced Cue-Induced Motivation and Food Addiction.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2016, Volume: 41, Issue:13

    Topics: Animals; Behavior, Addictive; Calcium; Cocaine; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Feeding Behavior; Food; Gene Expression Regulation; Locomotion; Male; Motivation; Nucleus Accumbens; Obesity; Rats; Rats, Sprague-Dawley; Receptors, AMPA

2016
Preventative treatment in an animal model of ADHD: Behavioral and biochemical effects of methylphenidate and its interactions with ovarian hormones in female rats.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2016, Volume: 26, Issue:9

    Topics: Animals; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Cocaine; Conditioning, Psychological; Delay Discounting; Disease Models, Animal; Dopamine; Female; Gonadal Hormones; Impulsive Behavior; Methylphenidate; Ovariectomy; Oxidopamine; Prefrontal Cortex; Rats, Sprague-Dawley; Receptors, Neurotransmitter; RNA, Messenger

2016
Role of dopamine neurotransmission in the long-term effects of repeated social defeat on the conditioned rewarding effects of cocaine.
    Progress in neuro-psychopharmacology & biological psychiatry, 2016, 11-03, Volume: 71

    Topics: Age Factors; Animals; Benzazepines; Cerebral Cortex; Cocaine; Conditioning, Operant; Disease Models, Animal; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Hippocampus; Male; Mice; Raclopride; Receptors, Dopamine; Reward; Statistics, Nonparametric; Stress, Psychological

2016
Nicotine produces long-term increases in cocaine reinforcement in adolescent but not adult rats.
    Brain research, 2017, 01-01, Volume: 1654, Issue:Pt B

    Topics: Aging; Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug Synergism; Male; Motor Activity; Nicotine; Nicotinic Agonists; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration; Sexual Maturation; Time Factors; Tobacco Use Disorder

2017
Role of a Lateral Orbital Frontal Cortex-Basolateral Amygdala Circuit in Cue-Induced Cocaine-Seeking Behavior.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2017, Volume: 42, Issue:3

    Topics: Animals; Basolateral Nuclear Complex; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Male; Optogenetics; Prefrontal Cortex; Rats; Rats, Sprague-Dawley

2017
The infralimbic and prelimbic cortices contribute to the inhibitory control of cocaine-seeking behavior during a discriminative stimulus task in rats.
    Addiction biology, 2017, Volume: 22, Issue:6

    Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Discrimination, Psychological; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Male; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Reward

2017
Genetic Deletion of the Nociceptin/Orphanin FQ Receptor in the Rat Confers Resilience to the Development of Drug Addiction.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2017, Volume: 42, Issue:3

    Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Learning; Narcotic Antagonists; Nociceptin Receptor; Rats; Rats, Transgenic; Rats, Wistar; Receptors, Opioid; Self Administration

2017
Dopamine D1 and D3 receptor interactions in cocaine reward and seeking in rats.
    Psychopharmacology, 2016, Volume: 233, Issue:23-24

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Antagonists; Drug Therapy, Combination; Drug-Seeking Behavior; Fluorenes; Male; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D3; Reinforcement, Psychology; Reward

2016
Topiramate increases the rewarding properties of cocaine in young-adult mice limiting its clinical usefulness.
    Psychopharmacology, 2016, Volume: 233, Issue:23-24

    Topics: Analysis of Variance; Animals; Anticonvulsants; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Fructose; Male; Mice; Reward; Topiramate; Ventral Tegmental Area

2016
Toward early estimation and treatment of addiction vulnerability: radial arm maze and N-acetyl cysteine before cocaine sensitization or nicotine self-administration in neonatal ventral hippocampal lesion rats.
    Psychopharmacology, 2016, Volume: 233, Issue:23-24

    Topics: Acetylcysteine; Animals; Animals, Newborn; Behavior, Addictive; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Disease Models, Animal; Drug-Seeking Behavior; Free Radical Scavengers; Hippocampus; Male; Memory Disorders; Memory, Short-Term; Nicotine; Nicotinic Agonists; Prefrontal Cortex; Rats; Rats, Sprague-Dawley

2016
Convergent transcriptomics and proteomics of environmental enrichment and cocaine identifies novel therapeutic strategies for addiction.
    Neuroscience, 2016, Dec-17, Volume: 339

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Computational Biology; Disease Models, Animal; Dopamine Uptake Inhibitors; Environment; Nucleus Accumbens; Proteome; Random Allocation; Rats, Sprague-Dawley; RNA, Messenger; Self Administration; Social Isolation; Transcriptome

2016
Cocaine-induced synaptic structural modification is differentially regulated by dopamine D1 and D3 receptors-mediated signaling pathways.
    Addiction biology, 2017, Volume: 22, Issue:6

    Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Male; Mice; Neuronal Plasticity; Receptors, Dopamine D1; Receptors, Dopamine D3; Signal Transduction

2017
Long-Lasting Impairment of mGluR5-Activated Intracellular Pathways in the Striatum After Withdrawal of Cocaine Self-Administration.
    The international journal of neuropsychopharmacology, 2017, 01-01, Volume: 20, Issue:1

    Topics: Acute Disease; Animals; Chronic Disease; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Disease Models, Animal; Dopamine Uptake Inhibitors; Excitatory Amino Acid Agents; Male; MAP Kinase Signaling System; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Self Administration; Substance Withdrawal Syndrome; Tissue Culture Techniques

2017
Reversal Learning Deficits Associated with Increased Frontal Cortical Brain-Derived Neurotrophic Factor Tyrosine Kinase B Signaling in a Prenatal Cocaine Exposure Mouse Model.
    Developmental neuroscience, 2016, Volume: 38, Issue:5

    Topics: Animals; Brain-Derived Neurotrophic Factor; Cocaine; Conditioning, Classical; Disease Models, Animal; Female; Frontal Lobe; Memory; Mice; Pregnancy; Prenatal Exposure Delayed Effects; Protein-Tyrosine Kinases; Receptor, trkB; Reversal Learning; Signal Transduction

2016
Cocaine Potency at the Dopamine Transporter Tracks Discrete Motivational States During Cocaine Self-Administration.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2017, Volume: 42, Issue:9

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Male; Motivation; Nucleus Accumbens; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration

2017
Garcinol Blocks the Reconsolidation of Multiple Cocaine-Paired Cues after a Single Cocaine-Reactivation Session.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2017, Volume: 42, Issue:9

    Topics: Administration, Intravenous; Animals; Catheters, Indwelling; Cocaine; Cocaine-Related Disorders; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Enzyme Inhibitors; Male; Memory Consolidation; Psychotropic Drugs; Rats, Sprague-Dawley; Self Administration; Terpenes

2017
A single cocaine exposure disrupts actin dynamics in the cortico-accumbal pathway of adolescent rats: modulation by a second cocaine injection.
    Psychopharmacology, 2017, Volume: 234, Issue:8

    Topics: Actins; Analysis of Variance; Animals; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Male; Neuronal Plasticity; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Reward

2017
Adolescent cocaine exposure enhances goal-tracking behavior and impairs hippocampal cell genesis selectively in adult bred low-responder rats.
    Psychopharmacology, 2017, Volume: 234, Issue:8

    Topics: Analysis of Variance; Animals; Behavior, Addictive; Behavior, Animal; Cocaine; Conditioning, Psychological; Disease Models, Animal; Goals; Hippocampus; Male; Neurogenesis; Rats; Rats, Sprague-Dawley; Reward

2017
Striatal D1 medium spiny neuron activation induces dyskinesias in parkinsonian mice.
    Movement disorders : official journal of the Movement Disorder Society, 2017, Volume: 32, Issue:4

    Topics: Animals; Antiparkinson Agents; Channelrhodopsins; Cocaine; Corpus Striatum; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dyskinesias; Female; Gene Expression Regulation; Levodopa; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Oxidopamine; Parkinsonian Disorders; Receptors, Dopamine D1; Sympatholytics

2017
In vivo interactions between α7 nicotinic acetylcholine receptor and nuclear peroxisome proliferator-activated receptor-α: Implication for nicotine dependence.
    Neuropharmacology, 2017, 05-15, Volume: 118

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Anesthetics, Local; Animals; Benzamides; Bridged Bicyclo Compounds; Cocaine; Conditioning, Operant; Disease Models, Animal; Fenofibrate; Hypolipidemic Agents; Male; Mice; Mice, Inbred ICR; Nicotine; Nicotinic Agonists; Oxazoles; PPAR alpha; Pyrimidines; Self Administration; Substance Withdrawal Syndrome; Tobacco Use Disorder; Tyrosine

2017
Cocaine self-administration in male and female rats perinatally exposed to PCBs: Evaluating drug use in an animal model of environmental contaminant exposure.
    Experimental and clinical psychopharmacology, 2017, Volume: 25, Issue:2

    Topics: Animals; Cocaine; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Environmental Exposure; Environmental Pollutants; Female; Male; Polychlorinated Biphenyls; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Long-Evans; Reinforcement, Psychology; Self Administration; Sex Factors

2017
Effect of cocaine on Fas-associated protein with death domain in the rat brain: individual differences in a model of differential vulnerability to drug abuse.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2009, Volume: 34, Issue:5

    Topics: Animals; Apoptosis; Behavior, Addictive; Brain; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Fas-Associated Death Domain Protein; Male; Phenotype; Poly(ADP-ribose) Polymerases; Rats; Rats, Inbred Strains; Rats, Sprague-Dawley; Receptors, Dopamine D2; RNA, Messenger; Substance-Related Disorders

2009
Repeated risperidone administration during puberty prevents the generation of the aggressive phenotype in a developmentally immature animal model of escalated aggression.
    Physiology & behavior, 2008, Sep-03, Volume: 95, Issue:1-2

    Topics: Age Factors; Aggression; Animals; Animals, Newborn; Antipsychotic Agents; Behavior, Animal; Body Weight; Cocaine; Cricetinae; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Mesocricetus; Phenotype; Reaction Time; Risperidone

2008
Pattern of intake and drug craving predict the development of cocaine addiction-like behavior in rats.
    Biological psychiatry, 2009, May-15, Volume: 65, Issue:10

    Topics: Animals; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Disease Models, Animal; Extinction, Psychological; Infusions, Intravenous; Male; Predictive Value of Tests; Punishment; Rats; Rats, Sprague-Dawley; Self Administration; Time Factors

2009
Repeated exposure to cocaine alters the modulation of mesocorticolimbic glutamate transmission by medial prefrontal cortex Group II metabotropic glutamate receptors.
    Journal of neurochemistry, 2008, Volume: 107, Issue:1

    Topics: Amino Acids; Animals; Cocaine; Cocaine-Related Disorders; Cystine; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug Administration Schedule; Excitatory Amino Acid Antagonists; Glutamic Acid; Limbic System; Male; Neural Pathways; Prefrontal Cortex; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Synaptic Transmission; Synaptic Vesicles; Ventral Tegmental Area; Xanthenes

2008
Administration of ziprasidone for 10 days increases cocaine toxicity in mice.
    Human & experimental toxicology, 2008, Volume: 27, Issue:6

    Topics: Animals; Antipsychotic Agents; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug Synergism; Longevity; Male; Mice; Mice, Inbred Strains; Piperazines; Seizures; Thiazoles; Time Factors; Withholding Treatment

2008
Histone deacetylase inhibitors decrease cocaine but not sucrose self-administration in rats.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, Sep-17, Volume: 28, Issue:38

    Topics: Animals; Brain; Brain Chemistry; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Disease Models, Animal; DNA Methylation; Dopamine Uptake Inhibitors; Enzyme Inhibitors; Epigenesis, Genetic; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Hydroxamic Acids; Locomotion; Male; Phenylbutyrates; Protein Processing, Post-Translational; Rats; Rats, Wistar; Self Administration; Sucrose

2008
Impairment of nigrostriatal dopamine neurotransmission by manganese is mediated by pre-synaptic mechanism(s): implications to manganese-induced parkinsonism.
    Journal of neurochemistry, 2008, Volume: 107, Issue:5

    Topics: Amphetamine; Animals; Cocaine; Corpus Striatum; Cyclohexanols; Disease Models, Animal; Dopamine; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Image Processing, Computer-Assisted; Macaca fascicularis; Male; Manganese; Parkinsonian Disorders; Positron-Emission Tomography; Substantia Nigra; Synaptic Transmission; Tetrabenazine; Tyrosine 3-Monooxygenase

2008
Effects of dopamine and NMDA receptors on cocaine-induced Fos expression in the striatum of Fischer rats.
    Brain research, 2008, Dec-03, Volume: 1243

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dual Specificity Phosphatase 1; Excitatory Amino Acid Antagonists; Extracellular Signal-Regulated MAP Kinases; Genes, Immediate-Early; Male; Phosphorylation; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred F344; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Time Factors; Up-Regulation

2008
Neuroadaptive changes in the rat brain GABA(B) receptors after withdrawal from cocaine self-administration.
    European journal of pharmacology, 2008, Dec-03, Volume: 599, Issue:1-3

    Topics: Animals; Autoradiography; Behavior, Animal; Brain Chemistry; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Male; Protein Binding; Rats; Rats, Wistar; Receptors, GABA-B; Self Administration; Substance Withdrawal Syndrome; Time Factors

2008
Phosphorylation-dependent trafficking of GluR2-containing AMPA receptors in the nucleus accumbens plays a critical role in the reinstatement of cocaine seeking.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, Oct-22, Volume: 28, Issue:43

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Food Preferences; Male; Nucleus Accumbens; Phosphorylation; Protein Transport; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Reinforcement Schedule; Reinforcement, Psychology; Self Administration; Serine

2008
Regulation of synaptic connectivity with chronic cocaine.
    The American journal of psychiatry, 2008, Volume: 165, Issue:11

    Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dendritic Spines; Disease Models, Animal; Gene Expression; Humans; MEF2 Transcription Factors; Myogenic Regulatory Factors; Neuronal Plasticity; Nucleus Accumbens; Receptors, Dopamine D1; Receptors, Dopamine D5; Reward; Signal Transduction; Synaptic Transmission

2008
Thermostable variants of cocaine esterase for long-time protection against cocaine toxicity.
    Molecular pharmacology, 2009, Volume: 75, Issue:2

    Topics: Animals; Carboxylic Ester Hydrolases; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Drug Design; Drug Overdose; Male; Mice; Structure-Activity Relationship; Substrate Specificity

2009
A bacterial cocaine esterase protects against cocaine-induced epileptogenic activity and lethality.
    Annals of emergency medicine, 2009, Volume: 54, Issue:3

    Topics: Animals; Anticonvulsants; Bacteria; Carboxylic Ester Hydrolases; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Electroencephalography; Hypnotics and Sedatives; Male; Midazolam; Rats; Rats, Sprague-Dawley; Seizures; Treatment Outcome

2009
Activity-dependent expression of ELAV/Hu RBPs and neuronal mRNAs in seizure and cocaine brain.
    Journal of neurochemistry, 2008, Volume: 107, Issue:6

    Topics: Analysis of Variance; Animals; Antigens, Surface; Brain; Cocaine; Dendrites; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; ELAV Proteins; ELAV-Like Protein 1; Electrophoretic Mobility Shift Assay; Fragile X Mental Retardation Protein; Gene Expression Regulation; Immunoprecipitation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Pilocarpine; Rats; Rats, Sprague-Dawley; RNA-Binding Proteins; RNA, Messenger; Signal Transduction; Status Epilepticus

2008
Renewed cocaine exposure produces transient alterations in nucleus accumbens AMPA receptor-mediated behavior.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, Nov-26, Volume: 28, Issue:48

    Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Agonists; Dopamine Uptake Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Motor Activity; Neuronal Plasticity; Nucleus Accumbens; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Dopamine D1; Substance Withdrawal Syndrome; Synaptic Transmission

2008
Paliperidone suppresses the development of the aggressive phenotype in a developmentally sensitive animal model of escalated aggression.
    Psychopharmacology, 2009, Volume: 203, Issue:4

    Topics: Age Factors; Aggression; Animals; Antipsychotic Agents; Behavior, Animal; Cocaine; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Isoxazoles; Male; Mesocricetus; Paliperidone Palmitate; Phenotype; Pyrimidines; Reaction Time

2009
Integrin expression is altered after acute and chronic cocaine.
    Neuroscience letters, 2009, Feb-06, Volume: 450, Issue:3

    Topics: Actins; Acute Disease; Animals; Chronic Disease; Cocaine; Cocaine-Related Disorders; Dendrites; Disease Models, Animal; Dopamine Uptake Inhibitors; Down-Regulation; Drug Administration Schedule; Integrin beta1; Integrin beta3; Male; Mice; Mice, Inbred C57BL; Nucleus Accumbens; Substance Withdrawal Syndrome; Synaptic Membranes; Up-Regulation

2009
Neuroadaptations in the cellular and postsynaptic group 1 metabotropic glutamate receptor mGluR5 and Homer proteins following extinction of cocaine self-administration.
    Neuroscience letters, 2009, Mar-13, Volume: 452, Issue:2

    Topics: Actins; Adaptation, Physiological; Animals; Brain; Brain Chemistry; Carrier Proteins; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Disease Models, Animal; Disks Large Homolog 4 Protein; Dopamine Uptake Inhibitors; Extinction, Psychological; Glutamic Acid; Homer Scaffolding Proteins; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Neuronal Plasticity; Nucleus Accumbens; Presynaptic Terminals; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Self Administration; Synaptic Transmission; Synaptosomes

2009
Repeated cocaine administration decreases 5-HT(2A) receptor-mediated serotonergic enhancement of synaptic activity in rat medial prefrontal cortex.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2009, Volume: 34, Issue:8

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug Administration Schedule; Drug Interactions; Excitatory Postsynaptic Potentials; Glutamic Acid; GTP-Binding Proteins; Male; Organ Culture Techniques; Patch-Clamp Techniques; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Substance Withdrawal Syndrome; Synaptic Transmission

2009
Nicotine is neuroprotective when administered before but not after nigrostriatal damage in rats and monkeys.
    Journal of neurochemistry, 2009, Volume: 109, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amphetamine; Analysis of Variance; Animals; Autoradiography; Cocaine; Conotoxins; Corpus Striatum; Cotinine; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Iodine Isotopes; Male; Motor Activity; Neuroprotective Agents; Neurotoxicity Syndromes; Nicotine; Oxidopamine; Protein Binding; Rats; Rats, Sprague-Dawley; Saimiri; Substantia Nigra; Time Factors

2009
Multitracer assessment of dopamine function after transplantation of embryonic stem cell-derived neural stem cells in a primate model of Parkinson's disease.
    Synapse (New York, N.Y.), 2009, Volume: 63, Issue:7

    Topics: Animals; Carbon Radioisotopes; Cells, Cultured; Cocaine; Disease Models, Animal; Dopamine; Dopamine Agents; Embryonic Stem Cells; Levodopa; Macaca fascicularis; Methamphetamine; Movement Disorders; Neurons; Parkinson Disease; Positron-Emission Tomography; Putamen; Raclopride; Tyrosine 3-Monooxygenase

2009
Role of mu- and delta-opioid receptors in the nucleus accumbens in cocaine-seeking behavior.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2009, Volume: 34, Issue:8

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; beta-Endorphin; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Male; Narcotic Antagonists; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Recurrence; Reward; Self Administration; Substance Withdrawal Syndrome

2009
Extended daily access to cocaine results in distinct alterations in Homer 1b/c and NMDA receptor subunit expression within the medial prefrontal cortex.
    Synapse (New York, N.Y.), 2009, Volume: 63, Issue:7

    Topics: Animals; Carrier Proteins; Central Nervous System Agents; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Homer Scaffolding Proteins; Immunoblotting; Male; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Self Administration; Time Factors; Ventral Tegmental Area

2009
Attenuated incubation of cocaine seeking in male rats trained to self-administer cocaine during periadolescence.
    Psychopharmacology, 2009, Volume: 204, Issue:4

    Topics: Age Factors; Animals; Behavior, Addictive; Behavior, Animal; Cocaine; Conditioning, Operant; Cues; Disease Models, Animal; Extinction, Psychological; Male; Rats; Rats, Wistar; Recurrence; Self Administration; Time Factors

2009
Blockade of the serotonin 5-HT2A receptor suppresses cue-evoked reinstatement of cocaine-seeking behavior in a rat self-administration model.
    Behavioral neuroscience, 2009, Volume: 123, Issue:2

    Topics: Analysis of Variance; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Extinction, Psychological; Fluorobenzenes; Food Deprivation; Male; Piperidines; Rats; Rats, Sprague-Dawley; Self Administration; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists

2009
Plasticity of L-type Ca2+ channels after cocaine withdrawal.
    Synapse (New York, N.Y.), 2009, Volume: 63, Issue:8

    Topics: Analysis of Variance; Animals; Calcium Channels; Calcium Channels, L-Type; Cocaine; Cross-Linking Reagents; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Dopamine Uptake Inhibitors; Gene Expression Regulation; In Vitro Techniques; Male; Motor Activity; Motor Cortex; Neuronal Plasticity; Prefrontal Cortex; Protein Transport; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Time Factors

2009
Escalation of food-maintained responding and sensitivity to the locomotor stimulant effects of cocaine in mice.
    Pharmacology, biochemistry, and behavior, 2009, Volume: 93, Issue:1

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Disease Models, Animal; Food; Male; Mice; Motor Activity; Reinforcement, Psychology; Self Administration

2009
Prenatal cocaine exposure differentially causes vascular dysfunction in adult offspring.
    Hypertension (Dallas, Tex. : 1979), 2009, Volume: 53, Issue:6

    Topics: Adult Children; Age Factors; Animals; Aorta; Cardiovascular Diseases; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Disease Progression; Endothelium, Vascular; Female; Male; Maternal Exposure; Mesenteric Arteries; Nitric Oxide; Pregnancy; Pregnancy, Animal; Prenatal Exposure Delayed Effects; Rats; Reference Values; Risk Factors; Sensitivity and Specificity; Sex Factors; Vasoconstriction

2009
Proteomic analysis of the nucleus accumbens of rats with different vulnerability to cocaine addiction.
    Neuropharmacology, 2009, Volume: 57, Issue:1

    Topics: Analysis of Variance; Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Disease Models, Animal; Dopamine Uptake Inhibitors; Electrophoresis, Gel, Two-Dimensional; Extinction, Psychological; Male; Nucleus Accumbens; Proteomics; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2009
Signaling pathway adaptations and novel protein kinase A substrates related to behavioral sensitization to cocaine.
    Journal of neurochemistry, 2009, Volume: 110, Issue:1

    Topics: Adaptation, Physiological; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cocaine; Cocaine-Related Disorders; Cyclic AMP-Dependent Protein Kinases; Dendrites; Disease Models, Animal; Dopamine Uptake Inhibitors; Intercellular Signaling Peptides and Proteins; Male; Mitogen-Activated Protein Kinase 1; Nerve Tissue Proteins; Neuronal Plasticity; Nucleus Accumbens; Phosphorylation; Proteomics; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Signal Transduction; Time Factors; Tubulin; Up-Regulation

2009
Prolonged withdrawal from repeated noncontingent cocaine exposure increases NMDA receptor expression and ERK activity in the nucleus accumbens.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009, May-27, Volume: 29, Issue:21

    Topics: Analysis of Variance; Animals; Butadienes; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug Administration Schedule; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Locomotion; Male; Nitriles; Nucleus Accumbens; Piperidines; Psychomotor Performance; Rats; Receptors, N-Methyl-D-Aspartate; Subcellular Fractions; Time Factors

2009
The encoding of cocaine vs. natural rewards in the striatum of nonhuman primates: categories with different activations.
    Neuroscience, 2009, Sep-29, Volume: 163, Issue:1

    Topics: Action Potentials; Animals; Basal Ganglia; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Disease Models, Animal; Dopamine Uptake Inhibitors; Macaca mulatta; Male; Neural Pathways; Neurons; Neuropsychological Tests; Photic Stimulation; Reinforcement, Psychology; Reward; Signal Processing, Computer-Assisted

2009
c-Fos expression associated with reinstatement of cocaine-seeking behavior by response-contingent conditioned cues.
    Synapse (New York, N.Y.), 2009, Volume: 63, Issue:10

    Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Extinction, Psychological; Hippocampus; Male; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; RNA, Messenger; Self Administration

2009
Cocaine modulates locomotion behavior in C. elegans.
    PloS one, 2009, Jun-17, Volume: 4, Issue:6

    Topics: Alleles; Animals; Automation; Behavior, Animal; Caenorhabditis elegans; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Models, Biological; Movement; Mutation; Serotonin; Software

2009
N-acetylaspartylglutamate (NAAG) inhibits intravenous cocaine self-administration and cocaine-enhanced brain-stimulation reward in rats.
    Neuropharmacology, 2010, Volume: 58, Issue:1

    Topics: Animals; Behavior, Addictive; Brain; Cocaine; Conditioning, Operant; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Electric Stimulation; Injections, Intravenous; Male; Microdialysis; Neuroprotective Agents; Organophosphorus Compounds; Rats; Rats, Long-Evans; Reinforcement Schedule; Reward; Self Administration

2010
The effect of olanzapine pretreatment on acute cocaine toxicity in mice.
    Clinical toxicology (Philadelphia, Pa.), 2009, Volume: 47, Issue:6

    Topics: Animals; Benzodiazepines; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Drug Antagonism; Injections, Intraperitoneal; Longevity; Male; Mice; Mice, Inbred Strains; Olanzapine; Poisoning; Seizures; Selective Serotonin Reuptake Inhibitors; Vasoconstrictor Agents

2009
Effect of non-dopaminergic drug treatment on Levodopa induced dyskinesias in MPTP monkeys: common implication of striatal neuropeptides.
    Neuropharmacology, 2010, Volume: 58, Issue:1

    Topics: Animals; Antiparkinson Agents; Benzoxazoles; Cocaine; Corpus Striatum; Disease Models, Animal; Docosahexaenoic Acids; Dopamine; Dopamine Uptake Inhibitors; Dynorphins; Dyskinesia, Drug-Induced; Enkephalins; Female; Iodine Isotopes; Levodopa; Macaca fascicularis; Naltrexone; Neuropeptides; Ovariectomy; Parkinsonian Disorders; Piperidines; Protein Precursors; RNA, Messenger; Sulfonamides; Tachykinins; Thiazoles; Time Factors

2010
Orexin/hypocretin is necessary for context-driven cocaine-seeking.
    Neuropharmacology, 2010, Volume: 58, Issue:1

    Topics: Analysis of Variance; Animals; Benzoxazoles; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Disease Models, Animal; Extinction, Psychological; Intracellular Signaling Peptides and Proteins; Male; Naphthyridines; Neuropeptides; Orexin Receptors; Orexins; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Reinforcement, Psychology; Self Administration; Time Factors; Urea

2010
Antidepressant treatment facilitates dopamine release and drug seeking behavior in a genetic animal model of depression.
    The European journal of neuroscience, 2009, Volume: 30, Issue:3

    Topics: Animals; Antidepressive Agents; Autoradiography; Behavior, Addictive; Behavior, Animal; Cocaine; Depression; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Microdialysis; Nucleus Accumbens; Rats

2009
Targeted disruption of cocaine-activated nucleus accumbens neurons prevents context-specific sensitization.
    Nature neuroscience, 2009, Volume: 12, Issue:8

    Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Cues; Daunorubicin; Disease Models, Animal; Dopamine Uptake Inhibitors; Learning; Male; Neuronal Plasticity; Neurons; Neuropharmacology; Neurotoxins; Nucleus Accumbens; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Rats, Transgenic

2009
Serotonergic lesions of the dorsal hippocampus differentially modulate locomotor hyperactivity induced by drugs of abuse in rats: implications for schizophrenia.
    Psychopharmacology, 2009, Volume: 206, Issue:4

    Topics: 5,7-Dihydroxytryptamine; Amphetamines; Animals; Cocaine; Disease Models, Animal; Dose-Response Relationship, Drug; Hippocampus; Hyperkinesis; Ketamine; Male; Phencyclidine; Rats; Rats, Sprague-Dawley; Schizophrenia; Serotonin

2009
A neurocomputational model for cocaine addiction.
    Neural computation, 2009, Volume: 21, Issue:10

    Topics: Algorithms; Animals; Brain; Brain Chemistry; Cocaine; Cocaine-Related Disorders; Computer Simulation; Decision Making; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Humans; Impulsive Behavior; Learning; Reinforcement, Psychology; Reward

2009
Nur77 mRNA levels and L-Dopa-induced dyskinesias in MPTP monkeys treated with docosahexaenoic acid.
    Neurobiology of disease, 2009, Volume: 36, Issue:1

    Topics: Acetylcholinesterase; Analysis of Variance; Animals; Antiparkinson Agents; Autoradiography; Brain; Cocaine; Disease Models, Animal; Docosahexaenoic Acids; Drug Interactions; Dyskinesia, Drug-Induced; Female; Iodine Isotopes; Levodopa; Macaca fascicularis; MPTP Poisoning; Nuclear Receptor Subfamily 4, Group A, Member 1; Protein Binding; RNA, Messenger; Statistics as Topic

2009
Stimulation of 5-HT(1B) receptors enhances cocaine reinforcement yet reduces cocaine-seeking behavior.
    Addiction biology, 2009, Volume: 14, Issue:4

    Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Extinction, Psychological; Hallucinogens; Male; Motivation; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Reinforcement, Psychology; Sucrose; Sweetening Agents

2009
The CB1 antagonist rimonabant (SR141716) blocks cue-induced reinstatement of cocaine seeking and other context and extinction phenomena predictive of relapse.
    Drug and alcohol dependence, 2009, Dec-01, Volume: 105, Issue:3

    Topics: Animals; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Corn Oil; Cues; Dietary Sucrose; Disease Models, Animal; Extinction, Psychological; Food, Formulated; Male; Mice; Mice, Inbred C57BL; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Recurrence; Reinforcement Schedule; Rimonabant; Self Administration; Water

2009
Performance under a Go/No-go task in rats selected for high and low impulsivity with a delay-discounting procedure.
    Behavioural pharmacology, 2009, Volume: 20, Issue:5-6

    Topics: Animals; Choice Behavior; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Discrimination Learning; Disease Models, Animal; Dopamine Uptake Inhibitors; Female; Food Preferences; Impulsive Behavior; Neuropsychological Tests; Rats; Rats, Wistar; Reaction Time; Reinforcement, Psychology; Saccharin; Self Administration

2009
Environmental enrichment produces a behavioral phenotype mediated by low cyclic adenosine monophosphate response element binding (CREB) activity in the nucleus accumbens.
    Biological psychiatry, 2010, Jan-01, Volume: 67, Issue:1

    Topics: Analysis of Variance; Animals; Animals, Newborn; Anxiety; Behavior, Animal; Behavioral Symptoms; Brain-Derived Neurotrophic Factor; Cocaine; Conditioning, Operant; CREB-Binding Protein; Depression; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Environment; Food Preferences; Male; Nucleus Accumbens; Phenotype; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; RNA, Messenger; RNA, Small Interfering; Self Administration

2010
Ceftriaxone restores glutamate homeostasis and prevents relapse to cocaine seeking.
    Biological psychiatry, 2010, Jan-01, Volume: 67, Issue:1

    Topics: Analysis of Variance; Animals; Antioxidants; Ceftriaxone; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cystine; Disease Models, Animal; Dopamine Uptake Inhibitors; Excitatory Amino Acid Transporter 2; Glutamic Acid; Male; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Self Administration; Time Factors; Tritium

2010
Low or high cocaine responding rats differ in striatal extracellular dopamine levels and dopamine transporter number.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 331, Issue:3

    Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Extracellular Space; Male; Microdialysis; Motor Activity; Protein Binding; Radioligand Assay; Rats; Rats, Sprague-Dawley; Reward

2009
Acquisition and reinstatement of MDMA-induced conditioned place preference in mice pre-treated with MDMA or cocaine during adolescence.
    Addiction biology, 2009, Volume: 14, Issue:4

    Topics: Age Factors; Animals; Choice Behavior; Cocaine; Conditioning, Psychological; Disease Models, Animal; Dose-Response Relationship, Drug; Hallucinogens; Male; Mice; N-Methyl-3,4-methylenedioxyamphetamine

2009
Sex differences in the self-administration of cannabinoids and other drugs of abuse.
    Psychoneuroendocrinology, 2009, Volume: 34 Suppl 1

    Topics: Analgesics, Opioid; Animals; Behavior, Addictive; Cannabinoids; Cocaine; Disease Models, Animal; Ethanol; Female; Humans; Illicit Drugs; Male; Nicotine; Self Administration; Sex Characteristics; Substance-Related Disorders

2009
Mechanisms of locomotor sensitization to drugs of abuse in a two-injection protocol.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2010, Volume: 35, Issue:2

    Topics: Analysis of Variance; Animals; Anisomycin; Cocaine; Corpus Striatum; Disease Models, Animal; Dizocilpine Maleate; Dopamine Agonists; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Antagonists; Dopamine Uptake Inhibitors; Drug Administration Routes; Drug Administration Schedule; Excitatory Amino Acid Antagonists; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Green Fluorescent Proteins; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Morphine; Motor Activity; Narcotics; Point Mutation; Protein Synthesis Inhibitors; Raclopride; Receptors, Dopamine D1; Substance-Related Disorders; Threonine; Time Factors

2010
Involvement of the lateral orbitofrontal cortex in drug context-induced reinstatement of cocaine-seeking behavior in rats.
    The European journal of neuroscience, 2009, Volume: 30, Issue:7

    Topics: Animals; Baclofen; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Environment; Extinction, Psychological; Frontal Lobe; GABA Agonists; Male; Muscimol; Random Allocation; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration; Ventral Tegmental Area

2009
Effects of extended cocaine access and cocaine withdrawal on choice between cocaine and food in rhesus monkeys.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2010, Volume: 35, Issue:2

    Topics: Animals; Choice Behavior; Cocaine; Conditioning, Operant; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Food; Food Preferences; Macaca mulatta; Male; Reinforcement Schedule; Self Administration; Substance Withdrawal Syndrome; Time Factors

2010
Reversal-specific learning impairments after a binge regimen of methamphetamine in rats: possible involvement of striatal dopamine.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2010, Volume: 35, Issue:2

    Topics: Analysis of Variance; Animals; Attention; Body Temperature; Central Nervous System Stimulants; Cocaine; Corpus Striatum; Discrimination, Psychological; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Learning Disabilities; Male; Methamphetamine; Neuropsychological Tests; Photic Stimulation; Protein Binding; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Long-Evans; Recognition, Psychology; Reversal Learning

2010
Footshock stress potentiates cue-induced cocaine-seeking in an animal model of relapse.
    Physiology & behavior, 2009, Dec-07, Volume: 98, Issue:5

    Topics: Anesthetics, Local; Animals; Behavior, Addictive; Biophysics; Cocaine; Conditioning, Operant; Cues; Disease Models, Animal; Electroshock; Extinction, Psychological; Male; Multivariate Analysis; Rats; Rats, Long-Evans; Reward; Secondary Prevention; Self Administration; Stress, Psychological

2009
Measuring levels of proteins by various technologies: can we learn more by measuring turnover?
    Biochemical pharmacology, 2010, Mar-01, Volume: 79, Issue:5

    Topics: Animals; Biomarkers; Brain; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Disease Models, Animal; Half-Life; Humans; Membrane Proteins; Nucleus Accumbens; Rats; Receptors, Dopamine D2; Species Specificity

2010
Cocaine-induced status epilepticus and death generate oxidative stress in prefrontal cortex and striatum of mice.
    Neurochemistry international, 2010, Volume: 56, Issue:1

    Topics: Animals; Antioxidants; Biomarkers; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Death, Sudden; Disease Models, Animal; Dopamine Uptake Inhibitors; Glutathione; Lipid Peroxidation; Male; Malondialdehyde; Mice; Nitrates; Nitrites; Oxidative Stress; Prefrontal Cortex; Status Epilepticus; Tocopherols

2010
Cocaine withdrawal-induced anxiety in females: impact of circulating estrogen and potential use of delta-opioid receptor agonists for treatment.
    Journal of neuroscience research, 2010, Volume: 88, Issue:4

    Topics: Analysis of Variance; Animals; Anxiety; Benzamides; Body Weight; Cocaine; Disease Models, Animal; Estrogens; Female; Maze Learning; Motor Activity; Ovariectomy; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Substance Withdrawal Syndrome

2010
Evaluation of nigrostriatal damage and its change over weeks in a rat model of Parkinson's disease: small animal positron emission tomography studies with [(11)C]beta-CFT.
    Nuclear medicine and biology, 2009, Volume: 36, Issue:8

    Topics: Animals; Carbon Radioisotopes; Cocaine; Corpus Striatum; Disease Models, Animal; Humans; Male; Parkinsonian Disorders; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Rats, Wistar

2009
Angiotensin II and CRF receptors in the central nucleus of the amygdala mediate hemodynamic response variability to cocaine in conscious rats.
    Brain research, 2010, Jan-14, Volume: 1309

    Topics: Amygdala; Angiotensin II Type 1 Receptor Blockers; Animals; Cocaine; Cocaine-Related Disorders; Consciousness; Corticotropin-Releasing Hormone; Disease Models, Animal; Dopamine Uptake Inhibitors; GABA Agonists; Hemodynamics; Hormone Antagonists; Losartan; Male; Muscimol; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Corticotropin-Releasing Hormone; Vascular Resistance; Vasoconstriction

2010
Prior chronic cocaine exposure in mice induces persistent alterations in cognitive function.
    Behavioural pharmacology, 2009, Volume: 20, Issue:8

    Topics: Animals; Attention; Cocaine; Cocaine-Related Disorders; Cognition; Conditioning, Classical; Conditioning, Operant; Disease Models, Animal; Impulsive Behavior; Inhibition, Psychological; Injections, Intraperitoneal; Male; Memory Disorders; Memory, Short-Term; Mice; Mice, Inbred C57BL; Motor Activity; Reinforcement Schedule; Reinforcement, Psychology; Reversal Learning; Time Factors

2009
Cortical activation during cocaine use and extinction in rhesus monkeys.
    Psychopharmacology, 2010, Volume: 208, Issue:2

    Topics: Animals; Behavior, Addictive; Behavior, Animal; Brain Mapping; Central Nervous System Stimulants; Cerebral Cortex; Cerebrovascular Circulation; Cocaine; Cocaine-Related Disorders; Cues; Disease Models, Animal; Extinction, Psychological; Female; Infusions, Intravenous; Macaca mulatta; Male; Positron-Emission Tomography; Prefrontal Cortex; Self Administration; Time Factors

2010
Amnestic effect of cocaine after the termination of its stimulant action.
    Progress in neuro-psychopharmacology & biological psychiatry, 2010, Feb-01, Volume: 34, Issue:1

    Topics: Amnesia; Analysis of Variance; Animals; Anxiety; Avoidance Learning; Cocaine; Discrimination, Psychological; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Male; Maze Learning; Mice; Motor Activity; Time Factors

2010
Reinstatement of cocaine seeking induced by drugs, cues, and stress in adolescent and adult rats.
    Psychopharmacology, 2010, Volume: 208, Issue:2

    Topics: Age Factors; Amphetamine-Related Disorders; Animals; Behavior, Addictive; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Cues; Disease Models, Animal; Extinction, Psychological; Infusions, Intravenous; Male; Photic Stimulation; Rats; Rats, Wistar; Recurrence; Self Administration; Stress, Psychological; Time Factors; Yohimbine

2010
Effects of clozapine on behavioral sensitization induced by cocaine.
    Psychiatry research, 2010, Jan-30, Volume: 175, Issue:1-2

    Topics: Analysis of Variance; Animals; Antipsychotic Agents; Behavior, Animal; Clozapine; Cocaine; CREB-Binding Protein; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Extracellular Signal-Regulated MAP Kinases; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Male; Mice; Mice, Inbred ICR; Motor Activity; Oncogene Protein v-akt; Prefrontal Cortex; Signal Transduction; Substance Withdrawal Syndrome

2010
Sex differences in the effects of allopregnanolone on yohimbine-induced reinstatement of cocaine seeking in rats.
    Drug and alcohol dependence, 2010, Mar-01, Volume: 107, Issue:2-3

    Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Anesthetics; Animals; Behavior, Addictive; Behavior, Animal; Cocaine; Conditioning, Operant; Disease Models, Animal; Extinction, Psychological; Female; Male; Pregnanolone; Rats; Rats, Wistar; Secondary Prevention; Self Administration; Sex Factors; Yohimbine

2010
Sex differences in the effects of cocaine abuse across the life span.
    Physiology & behavior, 2010, Jun-01, Volume: 100, Issue:3

    Topics: Age Factors; Animals; Brain; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Estrogens; Female; Humans; Male; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Receptors, Dopamine D1; Serotonin; Sex Factors; Time Factors

2010
Differences in D2 dopamine receptor availability and reaction to novelty in socially housed male monkeys during abstinence from cocaine.
    Psychopharmacology, 2010, Volume: 208, Issue:4

    Topics: Animals; Caudate Nucleus; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Exploratory Behavior; Fluorine Radioisotopes; Hierarchy, Social; Housing, Animal; Macaca fascicularis; Male; Positron-Emission Tomography; Putamen; Radioligand Assay; Receptors, Dopamine D2; Self Administration

2010
Specificity of prenatal cocaine exposure effects on cortical interneurons is independent from dopamine D1 receptor co-localization.
    Journal of chemical neuroanatomy, 2010, Volume: 39, Issue:4

    Topics: Animals; Calbindin 2; Calbindins; Calcium; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Female; Immunohistochemistry; Interneurons; Male; Nervous System Malformations; Prefrontal Cortex; Pregnancy; Prenatal Exposure Delayed Effects; Rabbits; Receptors, Dopamine D1; S100 Calcium Binding Protein G

2010
Impact of cocaine on adult hippocampal neurogenesis in an animal model of differential propensity to drug abuse.
    The European journal of neuroscience, 2010, Volume: 31, Issue:1

    Topics: Adult Stem Cells; Animals; Cell Differentiation; Cell Proliferation; Cell Survival; Cocaine; Cocaine-Related Disorders; Dentate Gyrus; Disease Models, Animal; Dopamine Uptake Inhibitors; Hippocampus; Male; Motor Activity; Neurogenesis; Neuroglia; Neurons; Rats; Rats, Inbred Strains; Species Specificity; Time Factors

2010
Lesion of the ventromedial nucleus of the thalamus blocks acute cocaine-induced changes in striatal glutamate.
    Synapse (New York, N.Y.), 2010, Volume: 64, Issue:6

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Denervation; Disease Models, Animal; Dopamine Uptake Inhibitors; Extracellular Fluid; Glutamic Acid; Male; Microdialysis; Neural Pathways; Neurosurgical Procedures; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Ventral Thalamic Nuclei

2010
Upregulation of L-type Ca(v)1 channels in the development of psychological dependence.
    Synapse (New York, N.Y.), 2010, Volume: 64, Issue:6

    Topics: Animals; Brain; Brain Chemistry; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Signaling; Cocaine; Disease Models, Animal; Frontal Lobe; Limbic System; Male; Methamphetamine; Mice; Morphine; Nifedipine; Substance-Related Disorders; Up-Regulation

2010
Gene expression changes in the medial prefrontal cortex and nucleus accumbens following abstinence from cocaine self-administration.
    BMC neuroscience, 2010, Feb-26, Volume: 11

    Topics: Analysis of Variance; Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Gene Expression; Male; Nucleus Accumbens; Oligonucleotide Array Sequence Analysis; Polymerase Chain Reaction; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Self Administration; Substance Withdrawal Syndrome; Time Factors

2010
Cocaine causes atrial Purkinje fiber damage.
    Ultrastructural pathology, 2010, Volume: 34, Issue:2

    Topics: Animals; Cocaine; Cricetinae; Disease Models, Animal; Female; Heart Atria; Longevity; Male; Maternal-Fetal Exchange; Mesocricetus; Microscopy, Electron, Transmission; Myocytes, Cardiac; Pregnancy; Purkinje Fibers; Vasoconstrictor Agents

2010
Effect of the use-dependent, nicotinic receptor antagonist BTMPS in the forced swim test and elevated plus maze after cocaine discontinuation in rats.
    Neuroscience letters, 2010, Apr-26, Volume: 474, Issue:2

    Topics: Analysis of Variance; Animals; Behavior, Animal; Cocaine; Decanoic Acids; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Male; Maze Learning; Nicotinic Antagonists; Piperidines; Rats; Rats, Wistar; Substance Withdrawal Syndrome; Swimming

2010
Dopamine receptor mechanisms mediate corticotropin-releasing factor-induced long-term potentiation in the rat amygdala following cocaine withdrawal.
    The European journal of neuroscience, 2010, Volume: 31, Issue:6

    Topics: Amygdala; Animals; Cocaine; Corticotropin-Releasing Hormone; Disease Models, Animal; Dopamine Agents; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agents; GABA Agents; In Vitro Techniques; Long-Term Potentiation; Male; Models, Neurological; Motor Activity; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Substance Withdrawal Syndrome; Time Factors

2010
Behavioral stress may increase the rewarding valence of cocaine-associated cues through a dynorphin/kappa-opioid receptor-mediated mechanism without affecting associative learning or memory retrieval mechanisms.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2010, Volume: 35, Issue:9

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Analysis of Variance; Anesthetics, Local; Animals; Association Learning; Behavior, Animal; Cocaine; Conditioning, Operant; Cues; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Dynorphins; Exploratory Behavior; Male; Mental Recall; Mice; Mice, Inbred C57BL; Naltrexone; Narcotic Antagonists; Receptors, Opioid, kappa; Reward; Stress, Psychological; Swimming

2010
Cocaine causes memory and learning impairments in rats: involvement of nuclear factor kappa B and oxidative stress, and prevention by topiramate.
    Journal of neurochemistry, 2010, Volume: 114, Issue:3

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Frontal Lobe; Fructose; Learning Disabilities; Male; Memory Disorders; Neuroprotective Agents; NF-kappa B; Oxidative Stress; Rats; Rats, Wistar; Topiramate

2010
Objective and quantitative evaluation of motor function in a monkey model of Parkinson's disease.
    Journal of neuroscience methods, 2010, Jul-15, Volume: 190, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Brain Mapping; Carbon Radioisotopes; Cocaine; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dyskinesia, Drug-Induced; Macaca fascicularis; Parkinsonian Disorders; Positron-Emission Tomography; Severity of Illness Index; Video Recording

2010
Cocaine sensitization models an anhedonia-like condition in rats.
    The international journal of neuropsychopharmacology, 2011, Volume: 14, Issue:3

    Topics: Adrenergic Uptake Inhibitors; Animals; Behavior, Animal; Cocaine; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Uptake Inhibitors; Imipramine; Male; Maze Learning; Motor Activity; Nucleus Accumbens; Phosphorylation; Pleasure; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Taste

2011
Transition to addiction is associated with a persistent impairment in synaptic plasticity.
    Science (New York, N.Y.), 2010, Jun-25, Volume: 328, Issue:5986

    Topics: Animals; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Glutamic Acid; Long-Term Synaptic Depression; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Self Administration; Synaptic Transmission

2010
Knowledge of treatment group does not bias assessment of time to seizure in an animal model of cocaine poisoning.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2010, Volume: 17, Issue:7

    Topics: Animals; Cocaine; Disease Models, Animal; Dogs; Humans; Observer Variation; Placebos; Prospective Studies; Seizures; Time Factors

2010
Assessment of ultrasonic vocalizations during drug self-administration in rats.
    Journal of visualized experiments : JoVE, 2010, Jul-22, Issue:41

    Topics: Animals; Cocaine; Disease Models, Animal; Male; Rats; Rats, Sprague-Dawley; Self Administration; Substance-Related Disorders; Ultrasonics; Vocalization, Animal

2010
Differential effects of allopregnanolone on the escalation of cocaine self-administration and sucrose intake in female rats.
    Psychopharmacology, 2010, Volume: 212, Issue:3

    Topics: Animals; Behavior, Addictive; Behavior, Animal; Cocaine; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Pregnanolone; Rats; Rats, Wistar; Self Administration; Sucrose; Yohimbine

2010
Inhibition of aldehyde dehydrogenase-2 suppresses cocaine seeking by generating THP, a cocaine use-dependent inhibitor of dopamine synthesis.
    Nature medicine, 2010, Volume: 16, Issue:9

    Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Animals; Berberine Alkaloids; Cocaine; Cocaine-Related Disorders; Cues; Disease Models, Animal; Dopamine; Dopamine Antagonists; Enzyme Activation; Infusions, Intravenous; Mitochondrial Proteins; Rats; Tyrosine 3-Monooxygenase

2010
Cocaine selectively increases proliferation in the adult murine hippocampus.
    Neuroscience letters, 2010, Nov-19, Volume: 485, Issue:2

    Topics: Animals; Cell Proliferation; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Hippocampus; Male; Mice; Mice, Inbred C57BL; Neurogenesis; Neuronal Plasticity

2010
Elevated BDNF after cocaine withdrawal facilitates LTP in medial prefrontal cortex by suppressing GABA inhibition.
    Neuron, 2010, Sep-09, Volume: 67, Issue:5

    Topics: Animals; Animals, Newborn; Biophysics; Brain-Derived Neurotrophic Factor; Carbazoles; Cocaine; Cocaine-Related Disorders; Diazepam; Disease Models, Animal; Dopamine Uptake Inhibitors; Electric Stimulation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Gene Expression Regulation; Green Fluorescent Proteins; Immunoprecipitation; In Vitro Techniques; Indole Alkaloids; Locomotion; Long-Term Potentiation; Neurotransmitter Agents; Patch-Clamp Techniques; Prefrontal Cortex; Pyramidal Cells; Pyridazines; Rats; Rats, Sprague-Dawley; Receptor, trkB; Receptors, GABA-A; Transfection

2010
Is slow-onset long-acting monoamine transport blockade to cocaine as methadone is to heroin? Implication for anti-addiction medications.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2010, Volume: 35, Issue:13

    Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Delayed-Action Preparations; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Electric Stimulation; Extinction, Psychological; Heroin; Male; Methadone; Nucleus Accumbens; Plasma Membrane Neurotransmitter Transport Proteins; Rats; Rats, Long-Evans; Self Administration; Tetrahydronaphthalenes

2010
Intrathecal cocaine delivery enables long-access self-administration with binge-like behavior in mice.
    Psychopharmacology, 2011, Volume: 213, Issue:1

    Topics: Animals; Behavior, Addictive; Circadian Rhythm; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Injections, Spinal; Male; Mice; Mice, Inbred C57BL; Self Administration; Substance Abuse, Intravenous

2011
Environmental living conditions introduced during forced abstinence alter cocaine-seeking behavior and Fos protein expression.
    Neuroscience, 2010, Dec-29, Volume: 171, Issue:4

    Topics: Analysis of Variance; Anesthetics, Local; Animals; Behavior, Animal; Brain; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Disease Models, Animal; Environment; Male; Oncogene Proteins v-fos; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Reinforcement, Psychology; Self Administration

2010
Role of dopamine D1 receptors in the activation of nucleus accumbens extracellular signal-regulated kinase (ERK) by cocaine-paired contextual cues.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2011, Volume: 36, Issue:2

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Extracellular Signal-Regulated MAP Kinases; Male; Neurons; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1

2011
Prolonged attenuation of the reinforcing strength of cocaine by chronic d-amphetamine in rhesus monkeys.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2011, Volume: 36, Issue:2

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Dextroamphetamine; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug Administration Schedule; Macaca mulatta; Male; Reinforcement, Psychology; Reward; Self Administration; Time Factors

2011
Inhibition of the mammalian target of rapamycin pathway by rapamycin blocks cocaine-induced locomotor sensitization.
    Neuroscience, 2011, Jan-13, Volume: 172

    Topics: Animals; Anti-Bacterial Agents; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Female; Rats; Rats, Sprague-Dawley; Sirolimus; TOR Serine-Threonine Kinases

2011
High-novelty-preference rats are predisposed to compulsive cocaine self-administration.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2011, Volume: 36, Issue:3

    Topics: Anesthetics, Local; Animals; Behavior, Animal; Cocaine; Compulsive Behavior; Conditioning, Operant; Disease Models, Animal; Exploratory Behavior; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Regression Analysis; Self Administration; Statistics, Nonparametric

2011
The first universal opioid ligand, (2S)-2-[(5R,6R,7R,14S)-N-cyclopropylmethyl-4,5-epoxy-6,14-ethano-3-hydroxy-6-methoxymorphinan-7-yl]-3,3-dimethylpentan-2-ol (BU08028): characterization of the in vitro profile and in vivo behavioral effects in mouse mode
    The Journal of pharmacology and experimental therapeutics, 2011, Volume: 336, Issue:3

    Topics: Acute Disease; Analgesics, Opioid; Animals; Buprenorphine; CHO Cells; Cocaine; Cricetinae; Cricetulus; Disease Models, Animal; Humans; Ligands; Male; Mice; Mice, Inbred ICR; Pain; Pain Measurement; Protein Binding; Receptors, Opioid; Reward

2011
A procedure for studying the footshock-induced reinstatement of cocaine seeking in laboratory rats.
    Journal of visualized experiments : JoVE, 2011, Jan-06, Issue:47

    Topics: Animals; Behavior, Addictive; Cocaine; Conditioning, Operant; Disease Models, Animal; Electroshock; Extinction, Psychological; Male; Rats; Rats, Inbred LEC; Recurrence; Stress, Psychological

2011
Regulation of MiR-124, Let-7d, and MiR-181a in the accumbens affects the expression, extinction, and reinstatement of cocaine-induced conditioned place preference.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2011, Volume: 36, Issue:6

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Disease Models, Animal; Extinction, Psychological; Gene Expression Regulation; Gene Regulatory Networks; Gene Silencing; HEK293 Cells; Humans; Male; MicroRNAs; Nucleus Accumbens; Rats; Rats, Wistar

2011
Dorsal as well as ventral striatal lesions affect levels of intravenous cocaine and morphine self-administration in rats.
    Neuroscience letters, 2011, Apr-08, Volume: 493, Issue:1-2

    Topics: Animals; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Male; Morphine; Narcotics; Neostriatum; Nucleus Accumbens; Rats; Rats, Long-Evans; Reward; Self Administration; Substance-Related Disorders

2011
Cocaine inverts rules for synaptic plasticity of glutamate transmission in the ventral tegmental area.
    Nature neuroscience, 2011, Volume: 14, Issue:4

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Glutamic Acid; Mice; Neuronal Plasticity; Organ Culture Techniques; Synaptic Transmission; Ventral Tegmental Area

2011
Effects of chronic cocaine administration on spatial learning and hippocampal spine density in two genetically different strains of rats.
    Neurobiology of learning and memory, 2011, Volume: 95, Issue:4

    Topics: Animals; Behavior, Addictive; CA1 Region, Hippocampal; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Dendritic Spines; Disease Models, Animal; Male; Maze Learning; Neuronal Plasticity; Rats; Rats, Inbred F344; Rats, Inbred Lew; Spatial Behavior; Species Specificity; Time Factors

2011
Adolescent nicotine exposure sensitizes cue-induced reinstatement of cocaine seeking in rats bred for high and low saccharin intake.
    Drug and alcohol dependence, 2011, Oct-01, Volume: 118, Issue:1

    Topics: Animals; Behavior, Addictive; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Disease Models, Animal; Extinction, Psychological; Female; Gene-Environment Interaction; Nicotine; Phenotype; Rats; Rats, Sprague-Dawley; Recurrence; Saccharin; Self Administration; Sweetening Agents

2011
Lesion of the rostral anterior cingulate cortex eliminates the aversiveness of spontaneous neuropathic pain following partial or complete axotomy.
    Pain, 2011, Volume: 152, Issue:7

    Topics: Analgesics; Animals; Avoidance Learning; Axotomy; Clonidine; Cocaine; Conditioning, Operant; Disease Models, Animal; Gyrus Cinguli; Hyperalgesia; Male; Neuralgia; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Sciatic Nerve; Spinal Nerves

2011
Prolonged toxic effects after cocaine challenge in butyrylcholinesterase/plasma carboxylesterase double knockout mice: a model for butyrylcholinesterase-deficient humans.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:8

    Topics: Animals; Apnea; Behavior, Animal; Butyrylcholinesterase; Carboxylesterase; Cocaine; Disease Models, Animal; Humans; Male; Metabolism, Inborn Errors; Mice; Mice, Knockout; Mutation; Time Factors

2011
Inhibition of β-adrenergic receptors induces a persistent deficit in retrieval of a cocaine-associated memory providing protection against reinstatement.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2011, Volume: 36, Issue:9

    Topics: Adrenergic beta-Antagonists; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Disease Models, Animal; Dopamine Uptake Inhibitors; Male; Memory; Memory Disorders; Neural Inhibition; Norepinephrine; Propranolol; Rats; Rats, Long-Evans; Receptors, Adrenergic, beta; Secondary Prevention

2011
Spontaneous locomotor activity correlates with the degranulation of mast cells in the meninges rather than in the thalamus: disruptive effect of cocaine.
    Brain research, 2011, Jun-13, Volume: 1395

    Topics: Akathisia, Drug-Induced; Animals; Cell Degranulation; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug Administration Schedule; Male; Mast Cells; Meninges; Mice; Mice, Inbred C57BL; Stress, Psychological

2011
Binge cocaine administration in adolescent rats affects amygdalar gene expression patterns and alters anxiety-related behavior in adulthood.
    Biological psychiatry, 2011, Sep-15, Volume: 70, Issue:6

    Topics: Age Factors; Amygdala; Animals; Anxiety; Cocaine; Disease Models, Animal; Fear; Gene Expression; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Learning; Male; Rats; Rats, Sprague-Dawley; Wnt Signaling Pathway

2011
Preclinical validation of a novel cocaine exposure therapy for relapse prevention.
    Biological psychiatry, 2011, Sep-15, Volume: 70, Issue:6

    Topics: Animals; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Disease Models, Animal; Drug Evaluation, Preclinical; Electric Stimulation; Extinction, Psychological; Male; Rats; Rats, Wistar; Reinforcement, Psychology; Secondary Prevention; Self Administration; Stress, Psychological

2011
SIV/macaque model of HIV infection in cocaine users: minimal effects of cocaine on behavior, virus replication, and CNS inflammation.
    Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 2012, Volume: 7, Issue:2

    Topics: Animals; Behavior, Animal; Brain; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Female; HIV Infections; Immunohistochemistry; Inflammation; Macaca; Male; Simian Acquired Immunodeficiency Syndrome; Virus Replication

2012
Blunted accumbal dopamine response to cocaine following chronic social stress in female rats: exploring a link between depression and drug abuse.
    Psychopharmacology, 2011, Volume: 218, Issue:1

    Topics: Animals; Behavior, Animal; Body Weight; Cocaine; Depression; Disease Models, Animal; Dopamine; Estrous Cycle; Female; Microdialysis; Nucleus Accumbens; Rats; Rats, Long-Evans; Saccharin; Serotonin; Sex Factors

2011
Does prenatal methamphetamine exposure affect the drug-seeking behavior of adult male rats?
    Behavioural brain research, 2011, Oct-10, Volume: 224, Issue:1

    Topics: Amphetamine; Analysis of Variance; Animals; Body Weight; Cocaine; Conditioning, Operant; Disease Models, Animal; Dopamine Agents; Female; Male; Methamphetamine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Substance-Related Disorders

2011
Correlative single photon emission computed tomography imaging of [123I]altropane binding in the rat model of Parkinson's.
    Nuclear medicine and biology, 2011, Volume: 38, Issue:5

    Topics: Animals; Behavior, Animal; Biomarkers; Cocaine; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Iodine Radioisotopes; Neostriatum; Neural Stem Cells; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Stem Cell Transplantation; Tomography, Emission-Computed, Single-Photon

2011
Blockade of kappa opioid receptors attenuates the development of depressive-like behaviors induced by cocaine withdrawal in rats.
    Neuropharmacology, 2012, Volume: 62, Issue:1

    Topics: Analysis of Variance; Animals; Cocaine; Conditioning, Operant; Depression; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug Administration Routes; Immobility Response, Tonic; Male; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Opioid, kappa; Reinforcement Schedule; Self Administration; Substance Withdrawal Syndrome; Swimming; Time Factors

2012
Effects of hypoxic-ischemic brain injury on striatal dopamine transporter in newborn piglets: evaluation of 11C-CFT PET/CT for DAT quantification.
    Nuclear medicine and biology, 2011, Volume: 38, Issue:8

    Topics: Animals; Animals, Newborn; Carbon Radioisotopes; Case-Control Studies; Cocaine; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Hypoxia-Ischemia, Brain; Male; Multimodal Imaging; Positron-Emission Tomography; Swine; Tomography, X-Ray Computed

2011
Treatment-like steady-state methadone in rats interferes with incubation of cocaine sensitization and associated alterations in gene expression.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2012, Volume: 22, Issue:2

    Topics: Analgesics, Opioid; Animals; Brain; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug Delivery Systems; Dynorphins; Gene Expression; Locomotion; Male; Methadone; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Opioid, mu; RNA, Messenger; Stereotyped Behavior

2012
Susceptibility to the long-term anxiogenic effects of an acute stressor is mediated by the activation of the glucocorticoid receptors.
    Neuropharmacology, 2011, Volume: 61, Issue:8

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Anti-Anxiety Agents; Cocaine; Conditioning, Operant; Corticotropin-Releasing Hormone; Diazepam; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Gene Expression Regulation; Hormone Antagonists; Hypothalamus; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mifepristone; Proto-Oncogene Proteins c-fos; Radioimmunoassay; Rats; Receptors, Glucocorticoid; RNA, Messenger; Serotonin Receptor Agonists; Stress, Psychological; Time Factors; Tyrosine 3-Monooxygenase

2011
Ceftriaxone prevents the induction of cocaine sensitization and produces enduring attenuation of cue- and cocaine-primed reinstatement of cocaine-seeking.
    Behavioural brain research, 2011, Nov-20, Volume: 225, Issue:1

    Topics: Analysis of Variance; Anesthetics, Local; Animals; Ceftriaxone; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Disease Models, Animal; Excitatory Amino Acid Transporter 1; Extinction, Psychological; Male; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration

2011
Brain-cocaine concentrations determine the dose self-administered by rats on a novel behaviorally dependent dosing schedule.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2011, Volume: 36, Issue:13

    Topics: Animals; Behavior, Animal; Brain Chemistry; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Male; Rats; Rats, Sprague-Dawley; Self Administration

2011
Acute cocaine exposure weakens GABA(B) receptor-dependent G-protein-gated inwardly rectifying K+ signaling in dopamine neurons of the ventral tegmental area.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Aug-24, Volume: 31, Issue:34

    Topics: Animals; Cocaine; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Drug Administration Schedule; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Male; Mice; Mice, Inbred C57BL; Neurons; Reaction Time; Receptors, GABA-B; Signal Transduction; Ventral Tegmental Area

2011
The missing variable: ultrasonic vocalizations reveal hidden sensitization and tolerance-like effects during long-term cocaine administration.
    Psychopharmacology, 2012, Volume: 219, Issue:4

    Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Disease Models, Animal; Drug Tolerance; Extinction, Psychological; Locomotion; Male; Motivation; Rats; Rats, Sprague-Dawley; Reward; Self Administration; Ultrasonics; Vocalization, Animal

2012
Novel cocaine vaccine linked to a disrupted adenovirus gene transfer vector blocks cocaine psychostimulant and reinforcing effects.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2012, Volume: 37, Issue:5

    Topics: Adenoviridae; Analysis of Variance; Animals; Brain; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Disease Models, Animal; Dopamine Uptake Inhibitors; Extinction, Psychological; Genetic Vectors; Haptens; Immunoglobulin G; Male; Methamphetamine; Motor Activity; Radioimmunoassay; Rats; Rats, Wistar; Reinforcement, Psychology; Self Administration; Time Factors; Transfer, Psychology; Tritium; Vaccination

2012
Molecular adaptations of apoptotic pathways and signaling partners in the cerebral cortex of human cocaine addicts and cocaine-treated rats.
    Neuroscience, 2011, Nov-24, Volume: 196

    Topics: Adult; Animals; Apoptosis; Apoptosis Inducing Factor; Caspase 3; Cerebral Cortex; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine and cAMP-Regulated Phosphoprotein 32; fas Receptor; Fas-Associated Death Domain Protein; Female; Humans; Male; Middle Aged; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Signal Transduction

2011
Slow phasic and tonic activity of ventral pallidal neurons during cocaine self-administration.
    Synapse (New York, N.Y.), 2012, Volume: 66, Issue:2

    Topics: Action Potentials; Animals; Basal Ganglia; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Globus Pallidus; Male; Neurons; Rats; Rats, Long-Evans; Reaction Time; Self Administration

2012
Genetic differences in the modulation of accumbal glutamate and γ-amino butyric acid levels after cocaine-induced reinstatement.
    Addiction biology, 2013, Volume: 18, Issue:4

    Topics: Analysis of Variance; Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Electrophoresis, Capillary; Extinction, Psychological; gamma-Aminobutyric Acid; Genetic Predisposition to Disease; Glutamic Acid; Microdialysis; Nucleus Accumbens; Rats; Rats, Inbred F344; Rats, Inbred Lew; Recurrence; Self Administration; Sodium Chloride; Species Specificity

2013
Regulation of type 1 inositol 1,4,5-triphosphate receptor by dopamine receptors in cocaine-induced place conditioning.
    Synapse (New York, N.Y.), 2012, Volume: 66, Issue:2

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Disease Models, Animal; Dopamine Antagonists; Dopamine Uptake Inhibitors; Inositol 1,4,5-Trisphosphate Receptors; Male; Mice; Nucleus Accumbens; Prefrontal Cortex; Receptors, Dopamine D1; Receptors, Dopamine D2; Signal Transduction

2012
Loss of striatal cannabinoid CB1 receptor function in attention-deficit / hyperactivity disorder mice with point-mutation of the dopamine transporter.
    The European journal of neuroscience, 2011, Volume: 34, Issue:9

    Topics: Animals; Attention Deficit Disorder with Hyperactivity; Cocaine; Corpus Striatum; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dronabinol; Excitatory Amino Acid Antagonists; Food Preferences; Gene Expression Regulation; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Point Mutation; Receptor, Cannabinoid, CB1; Receptors, GABA-B; Sucrose

2011
Serotonergic modulation of receptor occupancy in rats treated with L-DOPA after unilateral 6-OHDA lesioning.
    Journal of neurochemistry, 2012, Volume: 120, Issue:5

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Antiparkinson Agents; Autoradiography; Carbon Isotopes; Cocaine; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Dyskinesia, Drug-Induced; Female; Functional Laterality; Levodopa; Microdialysis; Motor Activity; Oxidopamine; Parkinson Disease; Positron-Emission Tomography; Protein Binding; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Serotonin; Serotonergic Neurons; Serotonin Receptor Agonists

2012
Prenatal cocaine exposure alters progenitor cell markers in the subventricular zone of the adult rat brain.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2012, Volume: 30, Issue:1

    Topics: Animals; Animals, Newborn; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Female; Male; Neurogenesis; Pregnancy; Prenatal Exposure Delayed Effects; Prosencephalon; Rats; Rats, Sprague-Dawley; Sex Characteristics; Stem Cells

2012
Cocaine-induced cortical microischemia in the rodent brain: clinical implications.
    Molecular psychiatry, 2012, Volume: 17, Issue:10

    Topics: Animals; Capillaries; Cerebral Angiography; Cerebral Cortex; Cerebrovascular Circulation; Cocaine; Disease Models, Animal; Female; Imaging, Three-Dimensional; Ischemia; Lasers; Mice; Regional Blood Flow; Tomography, Optical Coherence; Ultrasonography, Doppler, Transcranial; Vasoconstrictor Agents

2012
Dopamine D3 receptor function and cocaine exposure.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2012, Volume: 37, Issue:1

    Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Rats; Receptors, Dopamine D3

2012
Adenosine A2A receptors in the nucleus accumbens bi-directionally alter cocaine seeking in rats.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2012, Volume: 37, Issue:5

    Topics: Adenosine; Adenosine A2 Receptor Agonists; Analysis of Variance; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Disease Models, Animal; Dopamine Agonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Extinction, Psychological; Locomotion; Male; Nucleus Accumbens; Phenethylamines; Purinergic P2X Receptor Antagonists; Quinpirole; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Reinforcement, Psychology; Self Administration; Sucrose; Sweetening Agents; Xanthines

2012
Substantia nigra vulnerability after a single moderate diffuse brain injury in the rat.
    Experimental neurology, 2012, Volume: 234, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Atrophy; Brain Injuries; Calcium-Binding Proteins; Carrier Proteins; Cell Count; Chromatography, High Pressure Liquid; Cocaine; Disease Models, Animal; Dopamine; Electrochemical Techniques; Gene Expression Regulation; Homovanillic Acid; Isoquinolines; Male; Microfilament Proteins; Nerve Degeneration; Neurons; Protein Binding; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Stereotaxic Techniques; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase

2012
High anxiety is a predisposing endophenotype for loss of control over cocaine, but not heroin, self-administration in rats.
    Psychopharmacology, 2012, Volume: 222, Issue:1

    Topics: Animals; Anxiety; Cocaine; Disease Models, Animal; Heroin; Male; Maze Learning; Rats; Self Administration; Substance-Related Disorders

2012
Operant model of frustrated expected reward in mice.
    Addiction biology, 2012, Volume: 17, Issue:4

    Topics: Aggression; Analysis of Variance; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Eating; Extinction, Psychological; Frustration; Male; Mice; Mice, Inbred C57BL; Reinforcement Schedule; Reward; Self Administration

2012
Ventral tegmental area neurons are either excited or inhibited by cocaine's actions in the peripheral nervous system.
    Neuroscience, 2012, Apr-05, Volume: 207

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Dopaminergic Neurons; Injections, Intravenous; Male; Peripheral Nervous System; Rats; Rats, Long-Evans; Ventral Tegmental Area

2012
Chronic cocaine exposure during pregnancy increases postpartum neuroendocrine stress responses.
    Journal of neuroendocrinology, 2012, Volume: 24, Issue:4

    Topics: Animals; Body Weight; Brain; Cocaine; Corticosterone; Disease Models, Animal; Female; Immobility Response, Tonic; Male; Motor Activity; Oxytocin; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Stress, Psychological

2012
Role of mGluR5 neurotransmission in reinstated cocaine-seeking.
    Addiction biology, 2013, Volume: 18, Issue:1

    Topics: Analysis of Variance; Animals; Biotinylation; Blotting, Western; Carrier Proteins; Cocaine; Cocaine-Related Disorders; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Excitatory Amino Acid Agonists; Extinction, Psychological; Glycine; Homer Scaffolding Proteins; Male; Microinjections; Nucleus Accumbens; Phenylacetates; Protein Binding; Protein Transport; Pyridines; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Recurrence; Self Administration; Synaptic Transmission; Thiazoles

2013
Ethanol exposure during either adolescence or adulthood alters the rewarding effects of cocaine in adult rats.
    Pharmacology, biochemistry, and behavior, 2012, Volume: 101, Issue:3

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Injections, Intraperitoneal; Male; Rats; Rats, Sprague-Dawley; Reward

2012
Neuropeptide Y Y5 receptor antagonism attenuates cocaine-induced effects in mice.
    Psychopharmacology, 2012, Volume: 222, Issue:4

    Topics: Animals; Animals, Outbred Strains; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Cyclohexanes; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Drug Interactions; Female; Hyperkinesis; Male; Mice; Mice, Knockout; Nucleus Accumbens; Receptors, Neuropeptide Y; Reinforcement, Psychology; Self Administration; Xanthenes

2012
Predicting the clinical efficacy and potential adverse effects of a humanized anticocaine monoclonal antibody.
    Immunotherapy, 2012, Volume: 4, Issue:3

    Topics: Anesthetics, Local; Animals; Antibodies, Monoclonal, Humanized; Brain; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Humans; Immunization, Passive; Mice

2012
Chronic mild stress-induced depression-like symptoms in rats and abnormalities in catecholamine uptake in small arteries.
    Psychosomatic medicine, 2012, Volume: 74, Issue:3

    Topics: Analysis of Variance; Anhedonia; Animals; Arteries; Behavior, Animal; Blood Pressure; Catecholamines; Chronic Disease; Cocaine; Corticosterone; Depression; Depressive Disorder; Disease Models, Animal; Disease Susceptibility; Dopamine Uptake Inhibitors; Heart Rate; Male; Myography; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Rats; Resilience, Psychological; Stress, Psychological; Sucrose; Vascular Resistance; Vasoconstriction

2012
Neurobiological changes mediating the effects of chronic fluoxetine on cocaine use.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2012, Volume: 37, Issue:8

    Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Extinction, Psychological; Female; Fenfluramine; Fluoxetine; Functional Neuroimaging; Macaca mulatta; Male; Microdialysis; Positron-Emission Tomography; Prolactin; Receptor, Serotonin, 5-HT2A; Selective Serotonin Reuptake Inhibitors; Self Administration; Serotonin; Serotonin Plasma Membrane Transport Proteins

2012
Effects of acupuncture on stress-induced relapse to cocaine-seeking in rats.
    Psychopharmacology, 2012, Volume: 222, Issue:2

    Topics: Acupuncture Therapy; Animals; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Gene Expression Regulation; Male; Nucleus Accumbens; Phosphorylation; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration; Stress, Psychological

2012
Initial characterization of mice null for Lphn3, a gene implicated in ADHD and addiction.
    Brain research, 2012, Jun-29, Volume: 1463

    Topics: Animals; Attention Deficit Disorder with Hyperactivity; Behavior, Addictive; Cocaine; Disease Models, Animal; Female; Genotype; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Mutation; Receptors, G-Protein-Coupled; Receptors, Peptide; Signal Transduction

2012
Prefrontal synaptic markers of cocaine addiction-like behavior in rats.
    Molecular psychiatry, 2013, Volume: 18, Issue:6

    Topics: Amino Acids; Analysis of Variance; Animals; Biophysics; Bridged Bicyclo Compounds, Heterocyclic; Cocaine; Conditioning, Operant; Disease Models, Animal; Dopamine Uptake Inhibitors; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Long-Term Synaptic Depression; Male; Patch-Clamp Techniques; Prefrontal Cortex; Psychiatric Status Rating Scales; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Self Administration; Substance-Related Disorders; Synapses

2013
A new perspective for schizophrenia: TAAR1 agonists reveal antipsychotic- and antidepressant-like activity, improve cognition and control body weight.
    Molecular psychiatry, 2013, Volume: 18, Issue:5

    Topics: Analysis of Variance; Animals; Antipsychotic Agents; Attention; Benzodiazepines; Body Weight; Cocaine; Conditioning, Operant; Depression; Disease Models, Animal; Dopamine Uptake Inhibitors; Electroencephalography; Hallucinogens; Haloperidol; Humans; Macaca fascicularis; Magnetic Resonance Imaging; Male; Mental Recall; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microinjections; Motor Activity; Mutation; Olanzapine; Oocytes; Oxazoles; Phencyclidine; Phenethylamines; Protein Binding; Pyrrolidinones; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Reinforcement, Psychology; Schizophrenia; Swimming; Telemetry; Tritium; Xenopus

2013
Chemosensory cue conditioning with stimulants in a Caenorhabditis elegans animal model of addiction.
    Behavioral neuroscience, 2012, Volume: 126, Issue:3

    Topics: Animals; Behavior, Addictive; Caenorhabditis elegans; Chemotaxis; Cocaine; Conditioning, Psychological; Cues; Disease Models, Animal; Methamphetamine

2012
fMRI response in the medial prefrontal cortex predicts cocaine but not sucrose self-administration history.
    NeuroImage, 2012, Volume: 62, Issue:3

    Topics: Animals; Brain Mapping; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Magnetic Resonance Imaging; Neuronal Plasticity; Prefrontal Cortex; Rats; Rats, Long-Evans; Self Administration; Sucrose

2012
D-Serine facilitates the effectiveness of extinction to reduce drug-primed reinstatement of cocaine-induced conditioned place preference.
    Neuropharmacology, 2013, Volume: 64

    Topics: Animals; Antimetabolites; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Combined Modality Therapy; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Excitatory Amino Acid Agonists; Extinction, Psychological; Male; Nootropic Agents; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Secondary Prevention; Serine; Spatial Behavior; Stereoisomerism

2013
Double dissociation of the dorsomedial and dorsolateral striatal control over the acquisition and performance of cocaine seeking.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2012, Volume: 37, Issue:11

    Topics: Analysis of Variance; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Corpus Striatum; Disease Models, Animal; Dopamine Antagonists; Dopamine Uptake Inhibitors; Flupenthixol; Male; Rats; Reinforcement Schedule; Reinforcement, Psychology; Self Administration

2012
Reduced forebrain serotonin transmission is causally involved in the development of compulsive cocaine seeking in rats.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2012, Volume: 37, Issue:11

    Topics: 3,4-Dihydroxyphenylacetic Acid; 5,7-Dihydroxytryptamine; Animals; Behavior, Addictive; Cocaine; Conditioning, Operant; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Hydroxyindoleacetic Acid; Male; Prosencephalon; Punishment; Rats; Reinforcement Schedule; Reinforcement, Psychology; Self Administration; Serotonin; Serotonin Agents; Synaptic Transmission; Time Factors

2012
Delayed developmental changes in neonatal vocalizations correlates with variations in ventral medial hypothalamus and central amygdala development in the rodent infant: effects of prenatal cocaine.
    Behavioural brain research, 2012, Dec-01, Volume: 235, Issue:2

    Topics: Acoustic Stimulation; Age Factors; Amygdala; Analysis of Variance; Animals; Animals, Newborn; Bromodeoxyuridine; Cell Count; Cell Proliferation; Cocaine; Developmental Disabilities; Disease Models, Animal; Dopamine Uptake Inhibitors; Female; Fourier Analysis; Gestational Age; Hypothalamus, Middle; Male; Phosphopyruvate Hydratase; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Sex Factors; Time Factors; Vocalization, Animal

2012
Blockade of dopamine D3 receptors in the nucleus accumbens and central amygdala inhibits incubation of cocaine craving in rats.
    Addiction biology, 2013, Volume: 18, Issue:4

    Topics: Amygdala; Analysis of Variance; Animals; Cocaine; Cocaine-Related Disorders; Cues; Disease Models, Animal; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Humans; Locomotion; Male; Microinjections; Nitriles; Nucleus Accumbens; Rats; Receptors, Dopamine D3; Reinforcement, Psychology; Secondary Prevention; Self Administration; Sucrose; Tetrahydroisoquinolines; Time Factors

2013
Xanthine oxidase contributes to mitochondrial ROS generation in an experimental model of cocaine-induced diastolic dysfunction.
    Journal of cardiovascular pharmacology, 2012, Volume: 60, Issue:6

    Topics: Adenosine Triphosphate; Allopurinol; Animals; Antioxidants; Cocaine; Diastole; Disease Models, Animal; Electron Transport Complex I; Electron Transport Complex III; Energy Metabolism; Enzyme Inhibitors; Hemodynamics; Male; Mitochondria, Heart; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxides; Ventricular Dysfunction, Left; Ventricular Function, Left; Xanthine Oxidase

2012
Time course of cocaine-induced behavioral and neurochemical plasticity.
    Addiction biology, 2014, Volume: 19, Issue:4

    Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Glutamic Acid; Male; Neuronal Plasticity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration; Substance Withdrawal Syndrome; Time Factors

2014
Effects of adolescent nicotine exposure and withdrawal on intravenous cocaine self-administration during adulthood in male C57BL/6J mice.
    Addiction biology, 2014, Volume: 19, Issue:1

    Topics: Adolescent; Adolescent Behavior; Age of Onset; Analysis of Variance; Animals; Body Weight; Catheterization; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cotinine; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Extinction, Psychological; Humans; Infusion Pumps, Implantable; Male; Mice; Mice, Inbred C57BL; Nicotine; Random Allocation; Rats; Self Administration; Tobacco Use Disorder

2014
Effects of pretreatment with etomidate, ketamine, phenytoin, and phenytoin/midazolam on acute, lethal cocaine toxicity.
    Neurological research, 2012, Volume: 34, Issue:10

    Topics: Animals; Cocaine; Disease Models, Animal; Etomidate; Ketamine; Mice; Midazolam; Phenytoin; Random Allocation; Rats; Seizures; Treatment Outcome

2012
Exaggerated cue-induced reinstatement of cocaine seeking but not incubation of cocaine craving in a developmental rat model of schizophrenia.
    Psychopharmacology, 2013, Volume: 226, Issue:1

    Topics: Animals; Animals, Newborn; Brain Mapping; Cocaine; Cocaine-Related Disorders; Cues; Diagnosis, Dual (Psychiatry); Disease Models, Animal; Drug-Seeking Behavior; Extinction, Psychological; Female; Hippocampus; Rats; Rats, Long-Evans; Schizophrenia; Schizophrenic Psychology; Self Administration; Substance Withdrawal Syndrome

2013
Modafinil attenuates reinstatement of cocaine seeking: role for cystine-glutamate exchange and metabotropic glutamate receptors.
    Addiction biology, 2014, Volume: 19, Issue:1

    Topics: Amino Acid Transport System y+; Amino Acids; Analysis of Variance; Animals; Benzhydryl Compounds; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Excitatory Amino Acid Antagonists; Extinction, Psychological; Glutamates; Male; Microdialysis; Microinjections; Modafinil; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Secondary Prevention; Self Administration; Wakefulness-Promoting Agents; Xanthenes

2014
Short- and long-lasting behavioral and neurochemical adaptations: relationship with patterns of cocaine administration and expectation of drug effects in rats.
    Translational psychiatry, 2012, Oct-23, Volume: 2

    Topics: Adaptation, Physiological; Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Male; Microdialysis; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Time Factors

2012
Daily treadmill exercise attenuates cocaine cue-induced reinstatement and cocaine induced locomotor response but increases cocaine-primed reinstatement.
    Behavioural brain research, 2013, Feb-15, Volume: 239

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Disease Models, Animal; Exercise Therapy; Extinction, Psychological; Male; Motor Activity; Rats; Rats, Wistar; Secondary Prevention; Self Administration; Time Factors

2013
Pathway-specific dopaminergic deficits in a mouse model of Angelman syndrome.
    The Journal of clinical investigation, 2012, Volume: 122, Issue:12

    Topics: Angelman Syndrome; Animals; Benzazepines; Cocaine; Disease Models, Animal; Dopamine; Dopamine D2 Receptor Antagonists; Dopamine Uptake Inhibitors; Dopaminergic Neurons; Electric Stimulation; Female; Indoles; Male; Mice; Mice, Inbred C57BL; Motor Activity; Piperidines; Raclopride; Receptors, Dopamine D1; Reward; Self Stimulation; Substantia Nigra; Synaptic Transmission; Ubiquitin-Protein Ligases; Ventral Tegmental Area

2012
A drug-paired taste cue elicits withdrawal and predicts cocaine self-administration.
    Behavioural brain research, 2013, Mar-01, Volume: 240

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Rats; Rats, Sprague-Dawley; Recurrence; Reward; Saccharin; Substance Withdrawal Syndrome; Sweetening Agents; Taste

2013
Hierarchical recruitment of phasic dopamine signaling in the striatum during the progression of cocaine use.
    Proceedings of the National Academy of Sciences of the United States of America, 2012, Dec-11, Volume: 109, Issue:50

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Discrimination, Psychological; Disease Models, Animal; Disease Progression; Dopamine; Humans; Male; Rats; Rats, Wistar; Receptors, Dopamine; Self Administration; Signal Transduction; Time Factors

2012
Epigenetic inheritance of a cocaine-resistance phenotype.
    Nature neuroscience, 2013, Volume: 16, Issue:1

    Topics: Acetylation; Animals; Animals, Newborn; Azepines; Benzamides; Brain-Derived Neurotrophic Factor; Chromatin Immunoprecipitation; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Epigenomics; Feeding Behavior; Female; Food Preferences; Grooming; Histones; Male; Phenotype; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptor, trkB; Reinforcement, Psychology; RNA, Messenger; Self Administration; Sex Characteristics; Sucrose; Sweetening Agents

2013
Hippocampal neurogenesis protects against cocaine-primed relapse.
    Addiction biology, 2014, Volume: 19, Issue:4

    Topics: Analysis of Variance; Animals; Bromodeoxyuridine; Caspase 3; Cocaine; Cocaine-Related Disorders; Cues; Dentate Gyrus; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Electric Stimulation; Extinction, Psychological; Hippocampus; Male; Neurogenesis; Neurons; Rats; Rats, Wistar; Recurrence; Self Administration

2014
Alternative splicing of AMPA receptor subunits in the 6-OHDA-lesioned rat model of Parkinson's disease and L-DOPA-induced dyskinesia.
    Experimental neurology, 2013, Volume: 247

    Topics: Adamantane; Alternative Splicing; Animals; Antiparkinson Agents; Cocaine; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Iodine Isotopes; Levodopa; Male; Motor Activity; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Receptors, AMPA; RNA, Messenger; Sympatholytics

2013
Dopamine release in the dorsal striatum during cocaine-seeking behavior under the control of a drug-associated cue.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Jul-15, Volume: 22, Issue:14

    Topics: Animals; Appetitive Behavior; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Corpus Striatum; Cues; Disease Models, Animal; Dopamine; Extracellular Space; Male; Microdialysis; Rats; Rats, Inbred Strains; Reinforcement, Psychology; Self Administration

2002
Effects of pregnancy cocaine exposure on the mother and fetus: a murine model.
    Sheng li xue bao : [Acta physiologica Sinica], 2002, Aug-25, Volume: 54, Issue:4

    Topics: Animals; Brain; Cocaine; Disease Models, Animal; Dopamine; Female; Fetus; Liver; Malnutrition; Maternal Exposure; Maternal Nutritional Physiological Phenomena; Mice; Mothers; Placenta; Pregnancy; Serotonin

2002
Effect of glutamatergic systems on in vivo binding of [(125)I]beta-CIT in the brain of a rat model of Parkinson's disease.
    Synapse (New York, N.Y.), 2002, Volume: 46, Issue:1

    Topics: Animals; Autoradiography; Binding, Competitive; Cocaine; Disease Models, Animal; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Iodine Radioisotopes; Male; Neurons; Oxidopamine; Parkinsonian Disorders; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Wistar; Serotonin; Sympatholytics

2002
Cocaine activates the renin-angiotensin system in pregnant rabbits and alters the response to ischemia.
    Cardiovascular toxicology, 2002, Volume: 2, Issue:2

    Topics: Anesthetics, Local; Animals; Blood Flow Velocity; Blood Pressure; Blood Proteins; Cocaine; Coronary Circulation; Disease Models, Animal; Female; Heart Ventricles; Hematocrit; Injections, Intramuscular; Male; Models, Cardiovascular; Myocardial Ischemia; Pharmaceutical Vehicles; Pregnancy; Pregnancy Complications, Cardiovascular; Rabbits; Renin; Renin-Angiotensin System; Time Factors; Vasoconstrictor Agents; Ventricular Pressure

2002
Repeated cocaine administration alters the expression of genes in corticolimbic circuitry after a 3-week withdrawal: a DNA macroarray study.
    Journal of neurochemistry, 2002, Volume: 82, Issue:5

    Topics: Animals; Caudate Nucleus; Cerebral Cortex; Chronic Disease; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Drug Administration Schedule; Gene Expression Regulation; Immunoblotting; Limbic System; Male; Membrane Proteins; Nucleus Accumbens; Oligonucleotide Array Sequence Analysis; Prefrontal Cortex; Proteoglycans; Rats; Rats, Sprague-Dawley; Receptor, trkB; Receptors, Kainic Acid; Receptors, Purinergic P1; RNA, Messenger

2002
Ondansetron given in the acute withdrawal from a repeated cocaine sensitization dosing regimen reverses the expression of sensitization and inhibits self-administration.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2002, Volume: 27, Issue:4

    Topics: Acute Disease; Animals; Behavior, Animal; Brain; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Drug Tolerance; Male; Motor Activity; Ondansetron; Rats; Rats, Sprague-Dawley; Reaction Time; Self Administration; Serotonin Antagonists; Substance Withdrawal Syndrome

2002
Enhanced locomotor, reinforcing, and neurochemical effects of cocaine in serotonin 5-hydroxytryptamine 2C receptor mutant mice.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Nov-15, Volume: 22, Issue:22

    Topics: Animals; Behavior, Animal; Brain Chemistry; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Corpus Striatum; Disease Models, Animal; Dopamine; Drug Resistance; Exploratory Behavior; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Microdialysis; Motor Activity; Nucleus Accumbens; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Reinforcement, Psychology; Self Administration

2002
Neural plasticity and addiction: PI3-kinase and cocaine behavioral sensitization.
    Nature neuroscience, 2002, Volume: 5, Issue:12

    Topics: Animals; Behavior, Animal; Brain; Chromones; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Enzyme Inhibitors; Male; Morpholines; Motor Activity; Neuronal Plasticity; Neurons; Phosphatidylinositol 3-Kinases; Rats; Rats, Wistar; Signal Transduction

2002
Exaggerated cardiovascular effects of cocaine in conscious dogs with pacing-induced dilated cardiomyopathy.
    Journal of cardiac failure, 2002, Volume: 8, Issue:6

    Topics: Adrenergic beta-Agonists; Animals; Baroreflex; Biomarkers; Cardiac Pacing, Artificial; Cardiomyopathy, Dilated; Cardiovascular System; Cocaine; Denervation; Disease Models, Animal; Dobutamine; Dogs; Female; Hemodynamics; Injections, Intravenous; Isoproterenol; Male; Models, Cardiovascular; Nitroglycerin; Norepinephrine; Phenylephrine; Pressoreceptors; Sinoatrial Node; Vasoconstrictor Agents

2002
Time-dependent increases in brain-derived neurotrophic factor protein levels within the mesolimbic dopamine system after withdrawal from cocaine: implications for incubation of cocaine craving.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, Feb-01, Volume: 23, Issue:3

    Topics: Acoustic Stimulation; Amygdala; Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cocaine; Cocaine-Related Disorders; Cues; Disease Models, Animal; Dopamine; Drug Administration Routes; Extinction, Psychological; Limbic System; Male; Nerve Growth Factor; Nucleus Accumbens; Rats; Rats, Long-Evans; Reward; Self Administration; Substance Withdrawal Syndrome; Sucrose; Time; Ventral Tegmental Area

2003
Stress-induced suppression of the immune system after withdrawal from chronic cocaine.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 305, Issue:1

    Topics: Adrenalectomy; Animals; Cell Division; Cocaine; Corticosterone; Disease Models, Animal; Dopamine Uptake Inhibitors; Hormone Antagonists; Hypersensitivity, Delayed; Immune System; Leukocytes; Male; Mifepristone; Rats; Stress, Physiological; Substance Withdrawal Syndrome; T-Lymphocyte Subsets; T-Lymphocytes

2003
Striatal cell type-specific overexpression of DeltaFosB enhances incentive for cocaine.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, Mar-15, Volume: 23, Issue:6

    Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Doxycycline; Drug Administration Schedule; Dynorphins; Gene Expression; Mice; Mice, Transgenic; Motivation; Neurons; Organ Specificity; Proto-Oncogene Proteins c-fos; Reinforcement, Psychology; Self Administration; Substance P; Transgenes

2003
Baclofen attenuates conditioned locomotion to cues associated with cocaine administration and stabilizes extracellular glutamate levels in rat nucleus accumbens.
    Neuroscience, 2003, Volume: 118, Issue:1

    Topics: Animals; Baclofen; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Cues; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Extracellular Space; GABA Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Microdialysis; Motor Activity; Neurons; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Reward; Substance Withdrawal Syndrome; Synaptic Transmission

2003
Stimulus control of cocaine self-administration.
    Journal of the experimental analysis of behavior, 2003, Volume: 79, Issue:1

    Topics: Animals; Appetitive Behavior; Association Learning; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Extinction, Psychological; Generalization, Psychological; Male; Motivation; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Reinforcement Schedule; Self Administration

2003
GABA transmission in the nucleus accumbens is altered after withdrawal from repeated cocaine.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, Apr-15, Volume: 23, Issue:8

    Topics: Animals; Binding, Competitive; Chronic Disease; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine; Drug Administration Schedule; Extracellular Space; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Guanosine 5'-O-(3-Thiotriphosphate); Male; Microdialysis; Nucleus Accumbens; Phosphorylation; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Substance Withdrawal Syndrome; Synaptic Transmission

2003
Prefrontal glutamate release into the core of the nucleus accumbens mediates cocaine-induced reinstatement of drug-seeking behavior.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, Apr-15, Volume: 23, Issue:8

    Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Disease Models, Animal; Dopamine; Extinction, Psychological; Extracellular Space; GABA Agonists; Glutamic Acid; Male; Microdialysis; Neurons; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Recurrence; Reinforcement, Psychology; Self Administration

2003
Conditioned stimulus-induced reinstatement of extinguished cocaine seeking in C57BL/6 mice: a mouse model of drug relapse.
    Brain research, 2003, May-23, Volume: 973, Issue:1

    Topics: Animals; Behavior, Addictive; Cocaine; Conditioning, Psychological; Disease Models, Animal; Dose-Response Relationship, Drug; Mice; Mice, Inbred C57BL; Recurrence; Reinforcement, Psychology

2003
Molecular neuroadaptations in the accumbens and ventral tegmental area during the first 90 days of forced abstinence from cocaine self-administration in rats.
    Journal of neurochemistry, 2003, Volume: 85, Issue:6

    Topics: Adaptation, Physiological; Adenylyl Cyclases; Animals; Blotting, Western; Cocaine; Cocaine-Related Disorders; Cyclic AMP-Dependent Protein Kinases; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Disease Models, Animal; Male; Nucleus Accumbens; Rats; Rats, Long-Evans; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Self Administration; Substance Withdrawal Syndrome; Time Factors; Tyrosine 3-Monooxygenase; Ventral Tegmental Area

2003
The glucocorticoid receptor as a potential target to reduce cocaine abuse.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, Jun-01, Volume: 23, Issue:11

    Topics: Animals; Behavior, Animal; Brain; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Hormone Antagonists; Male; Mice; Mice, Transgenic; Mifepristone; Motivation; Motor Activity; Neurons; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; RNA, Messenger; Self Administration

2003
Escalation of cocaine self-administration does not depend on altered cocaine-induced nucleus accumbens dopamine levels.
    Journal of neurochemistry, 2003, Volume: 86, Issue:1

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Extracellular Space; Male; Microdialysis; Nucleus Accumbens; Rats; Rats, Wistar; Self Administration

2003
Cocaine increases mortality and cardiac mass in a murine transgenic model of acquired immune deficiency syndrome.
    Laboratory investigation; a journal of technical methods and pathology, 2003, Volume: 83, Issue:7

    Topics: Acquired Immunodeficiency Syndrome; Animals; Cardiomyopathies; Cocaine; Disease Models, Animal; Electrocardiography; Female; Heart Ventricles; Infusion Pumps, Implantable; Male; Mice; Mice, Inbred Strains; Mice, Transgenic; Myocardium; Organ Size; Survival Rate; Ventricular Dysfunction, Left

2003
Acquisition of an appetitive behavior prevents development of stress-induced neurochemical modifications in rat nucleus accumbens.
    Journal of neuroscience research, 2003, Aug-15, Volume: 73, Issue:4

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenylyl Cyclases; Analysis of Variance; Animals; Appetite; Behavior, Animal; Benzazepines; Binding Sites; Brain Chemistry; Carbohydrates; Cell Count; Cocaine; Conditioning, Operant; Disease Models, Animal; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Escape Reaction; Male; Maze Learning; Membrane Glycoproteins; Membrane Transport Proteins; Microdialysis; Nerve Tissue Proteins; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Stress, Physiological; Time Factors; Tritium; Vanilla

2003
Wheel access duration in rats: II. Day-night and within-session changes.
    Behavioral neuroscience, 2003, Volume: 117, Issue:4

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Male; Motor Activity; Photoperiod; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Time Factors

2003
Behavioral depression during cocaine withdrawal is associated with decreased spontaneous activity of ventral tegmental area dopamine neurons.
    Behavioral neuroscience, 2003, Volume: 117, Issue:4

    Topics: Animals; Circadian Rhythm; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Male; Motor Activity; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Substance Withdrawal Syndrome; Ventral Tegmental Area

2003
Dopamine responsiveness to drugs of abuse: A shell-core investigation in the nucleus accumbens of the mouse.
    Synapse (New York, N.Y.), 2003, Dec-15, Volume: 50, Issue:4

    Topics: Amphetamine; Anesthetics, Local; Animals; Calbindins; Central Nervous System Depressants; Central Nervous System Stimulants; Cocaine; Disease Models, Animal; Dopamine; Ethanol; Extracellular Space; Illicit Drugs; Immunohistochemistry; Male; Mice; Microdialysis; Morphine; Narcotics; Nicotine; Nicotinic Agonists; Nucleus Accumbens; S100 Calcium Binding Protein G; Substance-Related Disorders; Time Factors

2003
Cardiovascular responses elicited during binge administration of cocaine.
    Physiology & behavior, 2003, Volume: 80, Issue:1

    Topics: Acetylcholine; Animals; Blood Pressure; Cardiovascular System; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Drug Interactions; Heart Rate; Male; Nitroprusside; Rats; Rats, Sprague-Dawley; Serotonin; Vasodilator Agents

2003
Cocaine and other indirect-acting monoamine agonists differentially attenuate a naltrexone discriminative stimulus in morphine-treated rhesus monkeys.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 308, Issue:1

    Topics: Amphetamine; Animals; Biogenic Monoamines; Cocaine; Discrimination Learning; Disease Models, Animal; Dopamine Agents; Dopamine Uptake Inhibitors; Drug Interactions; Imipramine; Macaca mulatta; Morphine; Morphine Dependence; Naltrexone; Narcotics; Substance Withdrawal Syndrome

2004
Neuroadaptive changes in mesocorticolimbic dopamine and acetylcholine neurons following cocaine or saline self-administration are dependent on pre-existing individual differences.
    Neuroscience, 2003, Volume: 121, Issue:4

    Topics: Acetylcholine; Action Potentials; Adaptation, Physiological; Amygdala; Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine; Electric Stimulation; In Vitro Techniques; Limbic System; Male; Motivation; Neurons; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Wistar; Self Administration; Sodium Chloride; Substance Withdrawal Syndrome

2003
The transition from controlled to compulsive drug use is associated with a loss of sensitization.
    Brain research, 2004, Jan-02, Volume: 995, Issue:1

    Topics: Animals; Brain; Cell Count; Cocaine; Cocaine-Related Disorders; Compulsive Behavior; Disease Models, Animal; Drug Administration Schedule; Male; Motor Activity; Neurons; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Self Administration

2004
Cocaine enhances susceptibility to endotoxemic shock in a subset of rats.
    Critical care medicine, 2004, Volume: 32, Issue:1

    Topics: Animals; Blood Pressure; Cardiac Output; Cocaine; Disease Models, Animal; Disease Susceptibility; Dose-Response Relationship, Drug; Endotoxemia; Female; Hemodynamics; Injections, Intravenous; Male; Rats; Rats, Inbred Strains; Reference Values; Sensitivity and Specificity; Shock, Septic; Vascular Resistance

2004
[Basic study of dopamine transporter imaging with 131I-beta-CIT].
    Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi, 2003, Volume: 20, Issue:4

    Topics: Animals; Brain; Cats; Cocaine; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Female; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred Strains; Nerve Tissue Proteins; Parkinson Disease; Tomography, Emission-Computed, Single-Photon

2003
Evidence implicating cocaine as a possible risk factor for HIV infection.
    Journal of neuroimmunology, 2004, Volume: 147, Issue:1-2

    Topics: Animals; Cannabis; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; HIV; HIV Infections; Humans; In Vitro Techniques; Mice; Mice, SCID; Risk Factors

2004
Limbic and motor circuitry underlying footshock-induced reinstatement of cocaine-seeking behavior.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Feb-18, Volume: 24, Issue:7

    Topics: Amygdala; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Disease Models, Animal; Dopamine; Dopamine Antagonists; Efferent Pathways; Electroshock; GABA Agonists; Globus Pallidus; Glutamic Acid; Limbic System; Male; Microinjections; Motor Activity; Neostriatum; Neural Inhibition; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration; Septal Nuclei; Ventral Tegmental Area

2004
A single infusion of brain-derived neurotrophic factor into the ventral tegmental area induces long-lasting potentiation of cocaine seeking after withdrawal.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Feb-18, Volume: 24, Issue:7

    Topics: Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Disease Models, Animal; Enzyme Inhibitors; Extinction, Psychological; Infusions, Parenteral; Male; Nerve Growth Factor; Rats; Rats, Long-Evans; Substance Withdrawal Syndrome; Substantia Nigra; Time Factors; Ventral Tegmental Area

2004
Effects of dopamine transporter inhibitors on cocaine self-administration in rhesus monkeys: relationship to transporter occupancy determined by positron emission tomography neuroimaging.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 309, Issue:3

    Topics: Anesthesia; Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Isoflurane; Macaca mulatta; Membrane Glycoproteins; Membrane Transport Modulators; Membrane Transport Proteins; Nerve Tissue Proteins; Self Administration; Tomography, Emission-Computed; Tropanes

2004
Differential control over cocaine-seeking behavior by nucleus accumbens core and shell.
    Nature neuroscience, 2004, Volume: 7, Issue:4

    Topics: Animals; Appetitive Behavior; Association Learning; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Nucleus Accumbens; Rats; Rats, Inbred Strains; Reinforcement, Psychology; Self Administration

2004
Methadone maintenance reduces heroin- and cocaine-induced relapse without affecting stress-induced relapse in a rodent model of poly-drug use.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2004, Volume: 29, Issue:7

    Topics: Analysis of Variance; Animals; Behavior, Addictive; Behavior, Animal; Cocaine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Heroin; Locomotion; Methadone; Narcotics; Rats; Rats, Long-Evans; Secondary Prevention; Self Administration; Stress, Psychological; Substance-Related Disorders

2004
Cocaine seeking over extended withdrawal periods in rats: time dependent increases of responding induced by heroin priming over the first 3 months.
    Psychopharmacology, 2004, Volume: 176, Issue:1

    Topics: Animals; Behavior, Addictive; Cocaine; Conditioning, Operant; Disease Models, Animal; Drug Administration Schedule; Extinction, Psychological; Forecasting; Heroin; Injections, Intravenous; Injections, Subcutaneous; Male; Rats; Rats, Long-Evans; Recurrence; Self Administration; Substance Withdrawal Syndrome; Time Factors

2004
Neuropeptidergic characterization of the leptin receptor mutated obese Koletsky rat.
    Regulatory peptides, 2004, Jun-15, Volume: 119, Issue:1-2

    Topics: Adipose Tissue, Brown; Agouti-Related Protein; alpha-MSH; Amphetamines; Animals; Body Weight; Carrier Proteins; Cocaine; Diabetes Mellitus, Experimental; Disease Models, Animal; Female; Genotype; Hypothalamus; Intercellular Signaling Peptides and Proteins; Ion Channels; Male; Membrane Proteins; Mitochondrial Proteins; Mutation; Neuropeptide Y; Neuropeptides; Obesity; Oligonucleotides; Peptides; Phenotype; Proteins; Rats; Receptors, Cell Surface; Receptors, Leptin; Reproduction; Reverse Transcriptase Polymerase Chain Reaction; Uncoupling Protein 1; Up-Regulation

2004
Evidence for alterations in alpha2-adrenergic receptor sensitivity in rats exposed to repeated cocaine administration.
    Neuroscience, 2004, Volume: 125, Issue:3

    Topics: Adrenergic alpha-Agonists; Animals; Brain; Clonidine; Cocaine; Cocaine-Related Disorders; Corticosterone; Depressive Disorder; Disease Models, Animal; Down-Regulation; Drug Administration Schedule; Growth Hormone; Male; Norepinephrine; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Substance Withdrawal Syndrome; Synaptic Transmission

2004
The dopamine D1 receptor agonist and D2 receptor antagonist LEK-8829 attenuates reinstatement of cocaine-seeking in rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 2004, Volume: 369, Issue:6

    Topics: Animals; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine D2 Receptor Antagonists; Lysergic Acid; Male; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Self Administration

2004
Alterations in ionotropic glutamate receptor subunits during binge cocaine self-administration and withdrawal in rats.
    Journal of neurochemistry, 2004, Volume: 89, Issue:4

    Topics: Animals; Behavior, Animal; Blotting, Western; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Drug Administration Schedule; Male; Neostriatum; Nucleus Accumbens; Prefrontal Cortex; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Reinforcement, Psychology; Self Administration; Substance Withdrawal Syndrome; Substantia Nigra; Ventral Tegmental Area

2004
Modulation of long-term potentiation in the rat hippocampus following cocaine self-administration.
    Neuroscience, 2004, Volume: 127, Issue:1

    Topics: Adaptation, Physiological; Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Hippocampus; Long-Term Potentiation; Male; Memory; Neurons; Rats; Rats, Sprague-Dawley; Reaction Time; Self Administration; Substance Withdrawal Syndrome; Synaptic Transmission; Time Factors

2004
Cocaine and kappa-opioid withdrawal in Planaria blocked by D-, but not L-, glucose.
    Brain research, 2004, Aug-27, Volume: 1018, Issue:2

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adaptation, Physiological; Animals; Behavior, Addictive; Carbohydrate Conformation; Cocaine; Disease Models, Animal; Glucose; Narcotic Antagonists; Opioid-Related Disorders; Planarians; Receptors, Opioid, kappa; Substance Withdrawal Syndrome

2004
Dopamine and cyclic AMP-regulated phosphoprotein-32 phosphorylation pattern in cocaine and morphine-sensitized rats.
    Journal of neurochemistry, 2004, Volume: 90, Issue:4

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Dopamine and cAMP-Regulated Phosphoprotein 32; Male; Morphine; Morphine Dependence; Nerve Tissue Proteins; Phosphoproteins; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate

2004
Influence of handling or aversive stimulation during rats' neonatal or adolescence periods on oral cocaine self-administration and cocaine withdrawal.
    Behavioural pharmacology, 2004, Volume: 15, Issue:5-6

    Topics: Adolescent; Age Factors; Animals; Animals, Newborn; Cocaine; Cocaine-Related Disorders; Depression; Disease Models, Animal; Dopamine Uptake Inhibitors; Female; Humans; Male; Physical Conditioning, Animal; Rats; Rats, Wistar; Risk Factors; Stress, Psychological; Substance Withdrawal Syndrome

2004
Ecgonine methyl ester protects against cocaine lethality in mice.
    Journal of toxicology. Clinical toxicology, 2004, Volume: 42, Issue:4

    Topics: Animals; Cholinesterases; Cocaine; Disease Models, Animal; Female; Mice; Mice, Inbred ICR; Narcotics; Poisoning

2004
Acetaldehyde enhances acquisition of nicotine self-administration in adolescent rats.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2005, Volume: 30, Issue:4

    Topics: Acetaldehyde; Adolescent; Age Factors; Aging; Animals; Brain; Brain Chemistry; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Synergism; Humans; Male; Nicotiana; Nicotine; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Reinforcement, Psychology; Reward; Self Administration; Tobacco Use Disorder

2005
Heroin attenuates the negative consequences of cocaine in a runway model of self-administration.
    Pharmacology, biochemistry, and behavior, 2004, Volume: 79, Issue:2

    Topics: Animals; Avoidance Learning; Cocaine; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Heroin; Male; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration; Substance-Related Disorders

2004
Evaluation of the reinforcing effects of monoamine reuptake inhibitors under a concurrent schedule of food and i.v. drug delivery in rhesus monkeys.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2005, Volume: 30, Issue:4

    Topics: Adrenergic Uptake Inhibitors; Animals; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hyperactivity; Brain; Central Nervous System Stimulants; Cocaine; Desipramine; Dextroamphetamine; Disease Models, Animal; Dose-Response Relationship, Drug; Eating; Female; Infusion Pumps; Macaca mulatta; Methylphenidate; Propylamines; Reinforcement, Psychology; Self Administration; Substance-Related Disorders

2005
A novel method of cocaine delivery to fruit flies using a graphic arts airbrush.
    Journal of neuroscience methods, 2005, Jan-30, Volume: 141, Issue:1

    Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Drosophila melanogaster; Drug Delivery Systems; Drug Resistance; Ethanol; Genetic Testing; Male; Mutation; Reproducibility of Results; Stereotyped Behavior

2005
Central amygdala ERK signaling pathway is critical to incubation of cocaine craving.
    Nature neuroscience, 2005, Volume: 8, Issue:2

    Topics: Amygdala; Anesthetics, Local; Animals; Behavior, Addictive; Behavior, Animal; Blotting, Western; Butadienes; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Extinction, Psychological; Extracellular Signal-Regulated MAP Kinases; Food; Injections, Intravenous; Male; N-Methylaspartate; Nitriles; Phosphorylation; Rats; Rats, Long-Evans; Reinforcement, Psychology; Self Administration; Signal Transduction; Substance Withdrawal Syndrome; Time Factors

2005
Increased gabaergic input to ventral tegmental area dopaminergic neurons associated with decreased cocaine reinforcement in mu-opioid receptor knockout mice.
    Neuroscience, 2005, Volume: 130, Issue:2

    Topics: Afferent Pathways; Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine; gamma-Aminobutyric Acid; Male; Membrane Potentials; Mice; Mice, Knockout; Neural Inhibition; Neurons; Receptors, Opioid, mu; Reinforcement, Psychology; Self Administration; Synapses; Synaptic Transmission; Up-Regulation; Ventral Tegmental Area

2005
Increased activity of cyclin-dependent kinase 5 leads to attenuation of cocaine-mediated dopamine signaling.
    Proceedings of the National Academy of Sciences of the United States of America, 2005, Feb-01, Volume: 102, Issue:5

    Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Disease Models, Animal; Dopamine; Gene Expression Regulation, Enzymologic; Mice; Mice, Transgenic; Restriction Mapping; RNA; Signal Transduction; Spinal Cord; Synapses

2005
Description and quantification of cocaine withdrawal signs in Planaria.
    Brain research, 2005, Jan-25, Volume: 1032, Issue:1-2

    Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Planarians

2005
Evidence that the 5-HT1A autoreceptor is an important pharmacological target for the modulation of cocaine behavioral stimulant effects.
    Brain research, 2005, Feb-09, Volume: 1034, Issue:1-2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoreceptors; Behavior, Animal; Brain; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Male; Motor Activity; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists

2005
Neuropathology of the cerebral cortex observed in a range of animal models of prenatal cocaine exposure may reflect alterations in genes involved in the Wnt and cadherin systems.
    Synapse (New York, N.Y.), 2005, Volume: 56, Issue:2

    Topics: Animals; Blotting, Western; Cadherins; Cell Count; Cerebral Cortex; Cocaine; Disease Models, Animal; Female; Gene Expression Profiling; Gene Expression Regulation, Developmental; Intercellular Signaling Peptides and Proteins; Male; Mice; Neurons; Pregnancy; Prenatal Exposure Delayed Effects; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Wnt Proteins

2005
Effects of progesterone blockade over cocaine-induced genital reflexes of paradoxical sleep-deprived male rats.
    Hormones and behavior, 2005, Volume: 47, Issue:4

    Topics: Analysis of Variance; Animals; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Ejaculation; Genitalia, Male; Hormone Antagonists; Male; Mifepristone; Penile Erection; Progesterone; Rats; Rats, Wistar; Reflex; Sleep; Sleep Deprivation

2005
Blunted response to cocaine in the Flinders hypercholinergic animal model of depression.
    Neuroscience, 2005, Volume: 132, Issue:4

    Topics: Acetylcholine; Animals; Chromatography, High Pressure Liquid; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Depression; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Enkephalins; In Situ Hybridization; Male; Microdialysis; Motor Activity; Nucleus Accumbens; Protein Precursors; Rats; RNA, Messenger

2005
Ziprasidone pretreatment attenuates the lethal effects of cocaine in a mouse model.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2005, Volume: 12, Issue:5

    Topics: Acute Disease; Animals; Antipsychotic Agents; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Overdose; Injections, Intraperitoneal; Mice; Piperazines; Premedication; Random Allocation; Seizures; Single-Blind Method; Survival Analysis; Thiazoles; Treatment Outcome

2005
Glial cell line-derived neurotrophic factor-conjugated nanoparticles suppress acquisition of cocaine self-administration in rats.
    Experimental neurology, 2005, Volume: 194, Issue:1

    Topics: Animals; Behavior, Animal; Brain; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Corpus Striatum; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Drug Administration Routes; Ferric Compounds; Glial Cell Line-Derived Neurotrophic Factor; Male; Microinjections; Nanostructures; Nanotechnology; Nerve Growth Factors; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Self Administration; Treatment Outcome

2005
Immediate withdrawal from chronic "binge" cocaine administration increases mu-opioid receptor mRNA levels in rat frontal cortex.
    Brain research. Molecular brain research, 2005, Jun-13, Volume: 137, Issue:1-2

    Topics: Animals; Brain Chemistry; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Down-Regulation; Drug Administration Schedule; Enkephalins; Frontal Lobe; Male; Narcotic Antagonists; Protein Precursors; Rats; Rats, Inbred F344; Receptors, Opioid, mu; RNA, Messenger; Substance Withdrawal Syndrome; Time Factors

2005
Sensitization of the reinforcing effects of self-administered cocaine in rats: effects of dose and intravenous injection speed.
    The European journal of neuroscience, 2005, Volume: 22, Issue:1

    Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Injections, Intravenous; Male; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration; Time Factors

2005
The lack of A2A adenosine receptors diminishes the reinforcing efficacy of cocaine.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2006, Volume: 31, Issue:5

    Topics: Adenosine; Animals; Brain; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Female; Infusions, Intravenous; Male; Mice; Mice, Knockout; Motor Activity; Receptor, Adenosine A2A; Reinforcement, Psychology; Reward; Self Administration

2006
Extended cocaine self-administration and deprivation produces region-specific and time-dependent changes in connexin36 expression in rat brain.
    Synapse (New York, N.Y.), 2005, Dec-01, Volume: 58, Issue:3

    Topics: Animals; Brain; Cell Communication; Cocaine; Cocaine-Related Disorders; Connexins; Disease Models, Animal; Dopamine Uptake Inhibitors; Down-Regulation; Gap Junction delta-2 Protein; Gap Junctions; Hippocampus; Male; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; RNA, Messenger; Self Administration; Substance Withdrawal Syndrome; Time Factors

2005
Cocaine and sigma-1 receptors modulate HIV infection, chemokine receptors, and the HPA axis in the huPBL-SCID model.
    Journal of leukocyte biology, 2005, Volume: 78, Issue:6

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Ethylenediamines; Female; HIV; HIV Infections; Humans; Hypothalamo-Hypophyseal System; Immune Tolerance; Leukocytes, Mononuclear; Mice; Mice, Inbred BALB C; Mice, SCID; Pituitary-Adrenal System; Receptors, CCR5; Receptors, Chemokine; Receptors, CXCR4; Receptors, sigma; Sigma-1 Receptor; Transplantation, Heterologous; Viral Load

2005
moody encodes two GPCRs that regulate cocaine behaviors and blood-brain barrier permeability in Drosophila.
    Cell, 2005, Oct-07, Volume: 123, Issue:1

    Topics: Alternative Splicing; Animals; Behavior, Animal; Blood-Brain Barrier; Brain; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Drosophila melanogaster; Drosophila Proteins; Drug Tolerance; Male; Motor Activity; Neuroglia; Nicotine; Protein Structure, Tertiary; Receptors, G-Protein-Coupled; Substance-Related Disorders

2005
Differential behavioral and neurochemical effects of cocaine after early exposure to methylphenidate in an animal model of attention deficit hyperactivity disorder.
    Behavioural brain research, 2006, Feb-28, Volume: 167, Issue:2

    Topics: Age Factors; Animals; Attention Deficit Disorder with Hyperactivity; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Male; Methylphenidate; Nucleus Accumbens; Rats; Rats, Inbred SHR; Time Factors

2006
The influence of sex on extracellular dopamine and locomotor activity in C57BL/6J mice before and after acute cocaine challenge.
    Synapse (New York, N.Y.), 2006, Volume: 59, Issue:2

    Topics: Animals; Chromatography, High Pressure Liquid; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Extracellular Fluid; Female; Male; Mice; Mice, Inbred C57BL; Microdialysis; Motor Activity; Sex Factors

2006
Dopamine D1 or D2 receptor antagonism within the basolateral amygdala differentially alters the acquisition of cocaine-cue associations necessary for cue-induced reinstatement of cocaine-seeking.
    Neuroscience, 2006, Volume: 137, Issue:2

    Topics: Amygdala; Animals; Association; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Cues; Disease Models, Animal; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Extinction, Psychological; Male; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Reinforcement, Psychology; Secondary Prevention; Self Administration

2006
Antisense-induced reduction in nucleus accumbens cyclic AMP response element binding protein attenuates cocaine reinforcement.
    Neuroscience, 2006, Volume: 137, Issue:2

    Topics: Animals; Brain-Derived Neurotrophic Factor; Cocaine; Cocaine-Related Disorders; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Down-Regulation; Drug Tolerance; Genes, Immediate-Early; Male; Nucleus Accumbens; Oligodeoxyribonucleotides, Antisense; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration; Up-Regulation

2006
Motor-skill learning-associated gene regulation in the striatum: effects of cocaine.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2006, Volume: 31, Issue:12

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Disease Models, Animal; Dopamine; Dynorphins; Enkephalins; Gene Expression Regulation; Learning; Male; Motor Activity; Motor Skills; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Substance P; Up-Regulation

2006
Knockout of ERK1 enhances cocaine-evoked immediate early gene expression and behavioral plasticity.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2006, Volume: 31, Issue:12

    Topics: Animals; Behavior, Animal; Brain; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Corpus Striatum; Disease Models, Animal; Dopamine Uptake Inhibitors; Enkephalins; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Genes, Immediate-Early; Limbic System; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Proto-Oncogene Proteins c-fos; Ventral Tegmental Area

2006
Self-administration of heroin, cocaine and their combination under a discrete trial schedule of reinforcement in rats.
    Drug and alcohol dependence, 2006, May-20, Volume: 82, Issue:3

    Topics: Animals; Circadian Rhythm; Cocaine; Disease Models, Animal; Drug Interactions; Feeding Behavior; Heroin; Male; Rats; Rats, Inbred F344; Reinforcement, Psychology; Self Administration

2006
Alterations in BDNF and trkB mRNAs following acute or sensitizing cocaine treatments and withdrawal.
    Brain research, 2006, Feb-03, Volume: 1071, Issue:1

    Topics: Analysis of Variance; Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cocaine; Cocaine-Related Disorders; Diagnostic Imaging; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug Administration Schedule; Gene Expression Regulation; Hippocampus; In Situ Hybridization; Male; Motor Activity; Rats; Rats, Wistar; Reaction Time; Receptor, trkB; RNA, Messenger; Substance Withdrawal Syndrome; Swimming

2006
Cocaine increases actin cycling: effects in the reinstatement model of drug seeking.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Feb-01, Volume: 26, Issue:5

    Topics: Actins; Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Male; Microfilament Proteins; Nerve Tissue Proteins; Neuronal Plasticity; Nucleus Accumbens; Pseudopodia; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome

2006
AMPA-receptor GluR1 subunits are involved in the control over behavior by cocaine-paired cues.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2007, Volume: 32, Issue:2

    Topics: Animals; Behavior, Animal; Brain; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Extinction, Psychological; Glutamic Acid; Learning; Male; Mice; Mice, Knockout; Reaction Time; Receptors, AMPA; Reinforcement, Psychology; Reward; Self Administration; Synaptic Transmission

2007
Addiction-related alterations in D1 and D2 dopamine receptor behavioral responses following chronic cocaine self-administration.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2007, Volume: 32, Issue:2

    Topics: Animals; Behavior, Addictive; Brain; Chronic Disease; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Disease Models, Animal; Dopamine; Dopamine Agonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Hyperkinesis; Male; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Reward; Self Administration; Substance Withdrawal Syndrome

2007
Cocaine increases dopamine release by mobilization of a synapsin-dependent reserve pool.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Mar-22, Volume: 26, Issue:12

    Topics: alpha-Methyltyrosine; Animals; Brain; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Electric Stimulation; Enzyme Inhibitors; Medial Forebrain Bundle; Mice; Mice, Knockout; Neostriatum; Presynaptic Terminals; Reward; Synapsins; Synaptic Transmission; Synaptic Vesicles; Up-Regulation; Ventral Tegmental Area

2006
Extracellular-signal regulated kinase 1-dependent metabotropic glutamate receptor 5-induced long-term depression in the bed nucleus of the stria terminalis is disrupted by cocaine administration.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Mar-22, Volume: 26, Issue:12

    Topics: Animals; Anxiety Disorders; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Long-Term Synaptic Depression; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 3; Organ Culture Techniques; Receptor, Cannabinoid, CB1; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Reward; Septal Nuclei; Stress, Psychological; Synaptic Transmission

2006
Behavioral teratogenicity induced by nonforced maternal nicotine consumption.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2007, Volume: 32, Issue:3

    Topics: Animals; Association Learning; Attention Deficit and Disruptive Behavior Disorders; Behavior, Animal; Cocaine; Conditioning, Operant; Disease Models, Animal; Dopamine Uptake Inhibitors; Electroshock; Fear; Female; Mice; Mice, Inbred C57BL; Motor Activity; Nicotine; Nicotinic Agonists; Pregnancy; Prenatal Exposure Delayed Effects; Sex Factors

2007
Dopamine release is severely compromised in the R6/2 mouse model of Huntington's disease.
    Journal of neurochemistry, 2006, Volume: 97, Issue:3

    Topics: Age Factors; Animals; Cocaine; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Electrochemistry; Huntingtin Protein; Huntington Disease; In Vitro Techniques; Methamphetamine; Mice; Mice, Transgenic; Microelectrodes; Motor Activity; Nerve Tissue Proteins; Nuclear Proteins; Time Factors

2006
Augmented cocaine-induced accumbal dopamine efflux, motor activity and place preference in rats fed with a tryptophan-deficient diet.
    Neuroscience letters, 2006, Jun-19, Volume: 401, Issue:1-2

    Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine; Environment, Controlled; Exploratory Behavior; Extracellular Fluid; Food, Formulated; Hydroxyindoleacetic Acid; Hyperkinesis; Male; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Serotonin; Tryptophan

2006
A method for analyzing strain differences in acquisition of IV cocaine self-administration in mice.
    Behavior genetics, 2006, Volume: 36, Issue:4

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Male; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Probability; Self Administration; Species Specificity

2006
Mitochondrial dysfunction and caspase activation in rat cortical neurons treated with cocaine or amphetamine.
    Brain research, 2006, May-17, Volume: 1089, Issue:1

    Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Apoptosis; Caspases; Cell Line, Tumor; Central Nervous System Stimulants; Cerebral Cortex; Cocaine; Cocaine-Related Disorders; Cytochromes c; Disease Models, Animal; Electron Transport Chain Complex Proteins; Energy Metabolism; Humans; Membrane Potentials; Mitochondria; Mitochondrial Membranes; Nerve Degeneration; Neurons; Rats

2006
Elevation of glucocorticoids is necessary but not sufficient for the escalation of cocaine self-administration by chronic electric footshock stress in rats.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2007, Volume: 32, Issue:2

    Topics: Animals; Behavior, Addictive; Behavior, Animal; Chronic Disease; Cocaine; Cocaine-Related Disorders; Corticosterone; Disease Models, Animal; Dopamine Uptake Inhibitors; Electroshock; Male; Neurosecretory Systems; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Reward; Self Administration; Stress, Psychological; Up-Regulation

2007
Acute and repeated cocaine induces alterations in FosB/DeltaFosB expression in the paraventricular nucleus of the hypothalamus.
    Brain research, 2006, May-23, Volume: 1090, Issue:1

    Topics: Adaptation, Physiological; Animals; Brain Chemistry; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Hypothalamo-Hypophyseal System; Male; Paraventricular Hypothalamic Nucleus; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, Dopamine; Reward; Transcriptional Activation; Up-Regulation

2006
GABA(B) receptor-positive modulation decreases selective molecular and behavioral effects of cocaine.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2007, Volume: 32, Issue:2

    Topics: Animals; Baclofen; Behavior, Addictive; Brain; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Cyclic AMP Response Element-Binding Protein; Cyclopentanes; Disease Models, Animal; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; GABA Agonists; Hyperkinesis; Male; Mice; Mice, Inbred C57BL; Proto-Oncogene Proteins c-fos; Pyrimidines; Receptors, GABA-B; Signal Transduction; Synaptic Transmission

2007
Repeated l-DOPA treatment increases c-fos and BDNF mRNAs in the subthalamic nucleus in the 6-OHDA rat model of Parkinson's disease.
    Brain research, 2006, Jun-20, Volume: 1095, Issue:1

    Topics: Adrenergic Agents; Animals; Antiparkinson Agents; Brain-Derived Neurotrophic Factor; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug Administration Schedule; Gene Expression Regulation; Levodopa; Male; Oxidopamine; Parkinson Disease; Protein Binding; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; RNA, Messenger; Subthalamic Nucleus; Tritium

2006
Impairment in consolidation of learned place preference following dopaminergic neurotoxicity in mice is ameliorated by N-acetylcysteine but not D1 and D2 dopamine receptor agonists.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2007, Volume: 32, Issue:3

    Topics: Acetylcysteine; Animals; Behavior, Animal; Brain Chemistry; Cocaine; Conditioning, Operant; Disease Models, Animal; Dopamine; Dopamine Agents; Dopamine Agonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Free Radical Scavengers; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Glutathione; Learning Disabilities; Male; Methamphetamine; Mice; Neurotoxicity Syndromes; Tyrosine 3-Monooxygenase

2007
Use of surface enhanced laser desorption/ionization-time of flight mass spectrometry (SELDI-TOF MS) to study protein expression in a rat model of cocaine withdrawal.
    Journal of neuroscience methods, 2006, Nov-15, Volume: 158, Issue:1

    Topics: Animals; Behavior, Animal; Cocaine; Disease Models, Animal; Male; Protein Array Analysis; Proteins; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Subcellular Fractions; Substance Withdrawal Syndrome; Ventral Tegmental Area

2006
Preadolescent methylphenidate versus cocaine treatment differ in the expression of cocaine-induced locomotor sensitization during adolescence and adulthood.
    Biological psychiatry, 2006, Dec-01, Volume: 60, Issue:11

    Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Locomotion; Male; Methylphenidate; Mice; Pregnancy; Weight Gain

2006
A nitric oxide synthase inhibitor (L-NAME) attenuates abstinence-induced withdrawal from both cocaine and a cannabinoid agonist (WIN 55212-2) in Planaria.
    Brain research, 2006, Jul-12, Volume: 1099, Issue:1

    Topics: Analysis of Variance; Anesthetics, Local; Animals; Behavior, Animal; Benzoxazines; Cannabinoids; Cocaine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Morpholines; Motor Activity; Naphthalenes; NG-Nitroarginine Methyl Ester; Planarians; Substance Withdrawal Syndrome; Time Factors

2006
Reversal of cocaine-induced behavioral sensitization and associated phosphorylation of the NR2B and GluR1 subunits of the NMDA and AMPA receptors.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2007, Volume: 32, Issue:2

    Topics: Animals; Behavior, Addictive; Brain; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine; Dopamine Agonists; Dopamine Uptake Inhibitors; Drug Therapy, Combination; Glutamic Acid; Male; Neurons; Nucleus Accumbens; Ondansetron; Pergolide; Phosphorylation; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Serotonin Antagonists; Synaptic Transmission

2007
Aripiprazole blocks reinstatement of cocaine seeking in an animal model of relapse.
    Biological psychiatry, 2007, Mar-01, Volume: 61, Issue:5

    Topics: Animals; Antipsychotic Agents; Aripiprazole; Behavior, Addictive; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Extinction, Psychological; Male; Motor Activity; Piperazines; Quinolones; Rats; Rats, Sprague-Dawley; Secondary Prevention; Self Administration

2007
Microanatomy in 21 day rat brains exposed prenatally to cocaine.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2006, Volume: 24, Issue:5

    Topics: Animals; Brain; Cell Differentiation; Cocaine; Cocaine-Related Disorders; Dendrites; Disease Models, Animal; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Injections, Intravenous; Male; Nervous System Malformations; Neural Pathways; Neurons; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley

2006
An endogenous neuroprotectant substance, 1-methyl-1,2,3,4-tetrahydroisoquinoline (1MeTIQ), prevents the behavioral and neurochemical effects of cocaine reinstatement in drug-dependent rats.
    Journal of neural transmission (Vienna, Austria : 1996), 2007, Volume: 114, Issue:3

    Topics: Animals; Behavior, Animal; Brain; Brain Chemistry; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Limbic System; Male; Neural Pathways; Neuroprotective Agents; Norepinephrine; Rats; Reward; Secondary Prevention; Self Administration; Serotonin; Substance Withdrawal Syndrome; Tetrahydroisoquinolines; Ventral Tegmental Area

2007
A slow-onset, long-duration indanamine monoamine reuptake inhibitor as a potential maintenance pharmacotherapy for psychostimulant abuse: effects in laboratory rat models relating to addiction.
    Neuropharmacology, 2006, Volume: 51, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Behavior, Animal; Cocaine; Dialysis; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Homovanillic Acid; Hydroxyindoleacetic Acid; Indans; Indenes; Male; Neurotransmitter Uptake Inhibitors; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Self Administration; Substance-Related Disorders; Time Factors

2006
Protection against MDMA-induced dopaminergic neurotoxicity in mice by methyllycaconitine: involvement of nicotinic receptors.
    Neuropharmacology, 2006, Volume: 51, Issue:4

    Topics: Aconitine; Analysis of Variance; Animals; Cocaine; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Flow Cytometry; Male; Mice; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Neuroprotective Agents; Neurotoxicity Syndromes; Nicotinic Agonists; Nicotinic Antagonists; Radioligand Assay; Reactive Oxygen Species; Receptors, Nicotinic; Synaptosomes; Tritium

2006
Chronic cocaine exposure impairs progenitor proliferation but spares survival and maturation of neural precursors in adult rat dentate gyrus.
    The European journal of neuroscience, 2006, Volume: 24, Issue:2

    Topics: Animals; Bromodeoxyuridine; Cell Differentiation; Cell Proliferation; Cell Shape; Cell Survival; Chronic Disease; Cocaine; Cocaine-Related Disorders; Cognition Disorders; Dentate Gyrus; Disease Models, Animal; Dopamine Uptake Inhibitors; Doublecortin Domain Proteins; Doublecortin Protein; Down-Regulation; Drug Administration Schedule; Ki-67 Antigen; Male; Microtubule-Associated Proteins; Mitosis; Mossy Fibers, Hippocampal; Neurons; Neuropeptides; Rats; Rats, Wistar; Stem Cells

2006
Subadditive withdrawal from cocaine/kappa-opioid agonist combinations in Planaria.
    Brain research, 2006, Oct-09, Volume: 1114, Issue:1

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Anesthetics, Local; Animals; Behavior, Addictive; Behavior, Animal; Cocaine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Planarians; Receptors, Opioid, kappa; Substance Withdrawal Syndrome

2006
Genetic or pharmacological inactivation of the dopamine D1 receptor differentially alters the expression of regulator of G-protein signalling (Rgs) transcripts.
    The European journal of neuroscience, 2006, Volume: 24, Issue:3

    Topics: Animals; Animals, Newborn; Brain; Cocaine; Corpus Striatum; Disease Models, Animal; Dopamine Uptake Inhibitors; Female; Gene Expression Regulation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neural Pathways; Nucleus Accumbens; Prefrontal Cortex; Pregnancy; Prenatal Exposure Delayed Effects; Rabbits; Receptors, Dopamine D1; RGS Proteins; RNA, Messenger; Signal Transduction

2006
Cocaine-induced locomotor activity and Fos expression in nucleus accumbens are sensitized for 6 months after repeated cocaine administration outside the home cage.
    The European journal of neuroscience, 2006, Volume: 24, Issue:3

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug Administration Schedule; Drug Interactions; Enkephalins; GABA Agonists; Gene Expression; Male; Motor Activity; Neostriatum; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Time; Time Factors; Up-Regulation

2006
Reinforcing effects of smoked methamphetamine in rhesus monkeys.
    Psychopharmacology, 2006, Volume: 188, Issue:2

    Topics: Amphetamine-Related Disorders; Animals; Cocaine; Disease Models, Animal; Dose-Response Relationship, Drug; Macaca mulatta; Male; Methamphetamine; Reinforcement, Psychology; Self Administration; Smoking

2006
Effects of long-term food restriction on genital reflexes in paradoxically sleep-deprived male rats.
    Brain research, 2006, Oct-18, Volume: 1115, Issue:1

    Topics: Animals; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Eating; Ejaculation; Food Deprivation; Genitalia, Male; Male; Penile Erection; Rats; Rats, Wistar; Reflex; Sexual Behavior, Animal; Sexual Dysfunction, Physiological; Sleep Deprivation

2006
Modification of cocaine-induced behavioral and neurochemical effects by serotonin1A receptor agonist/antagonist in mice.
    Synapse (New York, N.Y.), 2006, Dec-01, Volume: 60, Issue:7

    Topics: Animals; Behavior, Animal; Brain; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Extracellular Fluid; Male; Mice; Motor Activity; Prefrontal Cortex; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists; Time Factors; Up-Regulation

2006
In vivo modulation of the Parkinsonian phenotype by Nrf2.
    Neurotoxicology, 2006, Volume: 27, Issue:6

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antineoplastic Agents; Autoradiography; Cocaine; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Drug Interactions; Iodine Isotopes; Male; Mice; Mice, Inbred ICR; Mice, Knockout; NF-E2-Related Factor 2; Parkinsonian Disorders; Phenotype; Thiones; Thiophenes

2006
Effects of short- and long-term estrogen and progesterone replacement on behavioral responses and c-fos mRNA levels in female rats after acute cocaine administration.
    Brain research, 2006, Dec-18, Volume: 1126, Issue:1

    Topics: Animals; Behavior, Animal; Brain; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug Administration Schedule; Drug Interactions; Estrogens; Estrous Cycle; Exploratory Behavior; Female; Hormone Replacement Therapy; Motor Activity; Ovariectomy; Progesterone; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred F344; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; RNA, Messenger

2006
Accumbal neurons that are activated during cocaine self-administration are spared from inhibitory effects of repeated cocaine self-administration.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2007, Volume: 32, Issue:5

    Topics: Action Potentials; Adaptation, Physiological; Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Exploratory Behavior; Male; Models, Neurological; Neural Inhibition; Neuronal Plasticity; Neurons; Nucleus Accumbens; Rats; Rats, Long-Evans; Self Administration; Synaptic Transmission

2007
Biphasic alterations in serotonin-1B (5-HT1B) receptor function during abstinence from extended cocaine self-administration.
    Journal of neurochemistry, 2006, Volume: 99, Issue:5

    Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Male; Motor Activity; Neural Pathways; Nucleus Accumbens; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Reward; Self Administration; Serotonin; Serotonin Receptor Agonists; Substance Withdrawal Syndrome; Synaptic Transmission; Ventral Tegmental Area

2006
Long-term potentiation (LTP) in the central amygdala (CeA) is enhanced after prolonged withdrawal from chronic cocaine and requires CRF1 receptors.
    Journal of neurophysiology, 2007, Volume: 97, Issue:1

    Topics: Amygdala; Animals; Calcium Channels, L-Type; Chronic Disease; Cocaine; Cocaine-Related Disorders; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug Administration Schedule; Electric Stimulation; Long-Term Potentiation; Male; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome; Time Factors

2007
Progesterone receptors activation after acute cocaine administration.
    Brain research, 2006, Dec-18, Volume: 1126, Issue:1

    Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Disease Models, Animal; DNA-Binding Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Male; Progesterone; Rats; Rats, Inbred F344; Reaction Time; Receptors, Progesterone; Up-Regulation

2006
Nrf2 gene deletion fails to alter psychostimulant-induced behavior or neurotoxicity.
    Brain research, 2007, Jan-05, Volume: 1127, Issue:1

    Topics: Amino Acid Transport System y+; Animals; Brain; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Gene Expression Regulation; Glutamic Acid; Methamphetamine; Mice; Mice, Knockout; Nerve Degeneration; NF-E2-Related Factor 2; Nucleus Accumbens; Oxidative Stress; Regulatory Elements, Transcriptional

2007
Context-dependent prefrontal cortex regulation of cocaine self-administration and reinstatement behaviors in rats.
    The European journal of neuroscience, 2006, Volume: 24, Issue:11

    Topics: Acoustic Stimulation; Anesthetics, Local; Animals; Cocaine; Cocaine-Related Disorders; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Environment; Environment, Controlled; Lidocaine; Male; Neural Pathways; Odorants; Photic Stimulation; Prefrontal Cortex; Rats; Reward; Self Administration

2006
Changes in levels of D1, D2, or NMDA receptors during withdrawal from brief or extended daily access to IV cocaine.
    Brain research, 2007, Feb-02, Volume: 1131, Issue:1

    Topics: Adaptation, Physiological; Animals; Binding, Competitive; Brain Chemistry; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Drug Administration Schedule; Glutamic Acid; Injections, Intravenous; Male; Neural Pathways; Nucleus Accumbens; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome; Synaptic Transmission

2007
Evaluation of reward processes in an animal model of depression.
    Psychopharmacology, 2007, Volume: 190, Issue:4

    Topics: Animals; Behavior, Animal; Body Weight; Central Nervous System Stimulants; Cocaine; Depression; Disease Models, Animal; Electric Stimulation; Exploratory Behavior; Food Preferences; Locomotion; Male; Olfactory Bulb; Rats; Rats, Sprague-Dawley; Reaction Time; Reward; Self Stimulation; Sensory Thresholds; Sucrose; Time Factors

2007
Chronic cocaine exposure in the SCID mouse model of HIV encephalitis.
    Brain research, 2007, Feb-23, Volume: 1134, Issue:1

    Topics: AIDS Dementia Complex; Animals; Astrocytes; Brain; Chronic Disease; Cocaine; Cocaine-Related Disorders; Cognition Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Fatigue; Gliosis; Male; Mice; Mice, SCID; Microglia

2007
Long-term cocaine self-administration under fixed-ratio and second-order schedules in monkeys.
    Psychopharmacology, 2007, Volume: 191, Issue:2

    Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Macaca mulatta; Male; Reinforcement Schedule; Self Administration

2007
Subchronic cannabinoid agonist (WIN 55,212-2) treatment during cocaine abstinence alters subsequent cocaine seeking behavior.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2007, Volume: 32, Issue:11

    Topics: Analgesics; Animals; Behavior, Animal; Benzoxazines; Cocaine; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Extinction, Psychological; Male; Maze Learning; Morpholines; Naphthalenes; Rats; Rats, Wistar; Self Administration; Substance Withdrawal Syndrome

2007
Compulsive drug seeking by rats under punishment: effects of drug taking history.
    Psychopharmacology, 2007, Volume: 194, Issue:1

    Topics: Anesthetics, Local; Animals; Animals, Outbred Strains; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Disease Models, Animal; Electroshock; Fear; Feeding Behavior; Male; Punishment; Rats; Reinforcement Schedule; Reward; Self Administration; Solutions; Sucrose; Time Factors

2007
Surgical adrenalectomy with diurnal corticosterone replacement slows escalation and prevents the augmentation of cocaine-induced reinstatement in rats self-administering cocaine under long-access conditions.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008, Volume: 33, Issue:4

    Topics: Adrenalectomy; Analysis of Variance; Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Corticosterone; Disease Models, Animal; Dopamine Uptake Inhibitors; Hormone Replacement Therapy; Male; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Time Factors

2008
A conflict rat model of cue-induced relapse to cocaine seeking.
    Psychopharmacology, 2007, Volume: 194, Issue:1

    Topics: Analysis of Variance; Anesthetics, Local; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Conflict, Psychological; Cues; Disease Models, Animal; Electroshock; Extinction, Psychological; Infusions, Intravenous; Male; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration; Time Factors

2007
Ziprasidone, diazepam, or the combination for prevention of cocaine toxicity in a mouse model.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2007, Volume: 14, Issue:8

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Confidence Intervals; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Male; Mice; Mice, Inbred Strains; Piperazines; Random Allocation; Reference Values; Sensitivity and Specificity; Statistics, Nonparametric; Survival Rate; Thiazoles

2007
The role of dorsal vs ventral striatal pathways in cocaine-seeking behavior after prolonged abstinence in rats.
    Psychopharmacology, 2007, Volume: 194, Issue:3

    Topics: Animals; Basal Ganglia; Behavior, Addictive; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Male; Rats; Rats, Sprague-Dawley; Recurrence; Reinforcement, Psychology; Self Administration; Substance Withdrawal Syndrome; Substantia Nigra

2007
Cocaine-induced decision-making deficits are mediated by miscoding in basolateral amygdala.
    Nature neuroscience, 2007, Volume: 10, Issue:8

    Topics: Action Potentials; Amygdala; Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Cues; Decision Making; Discrimination, Psychological; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Male; Motor Activity; N-Methylaspartate; Neurons; Odorants; Rats; Rats, Long-Evans

2007
Effects of GABA(B) receptor agents on cocaine priming, discrete contextual cue and food induced relapses.
    European journal of pharmacology, 2007, Oct-01, Volume: 571, Issue:2-3

    Topics: Animals; Baclofen; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Disease Models, Animal; Dose-Response Relationship, Drug; Extinction, Psychological; Feeding Behavior; GABA Agonists; GABA Antagonists; Injections, Intravenous; Male; Morpholines; Organophosphorus Compounds; Phenols; Rats; Rats, Wistar; Receptors, GABA-B; Reinforcement, Psychology; Secondary Prevention; Self Administration

2007
Human retinal pigment epithelial cell implants ameliorate motor deficits in two rat models of Parkinson disease.
    Journal of neuropathology and experimental neurology, 2007, Volume: 66, Issue:7

    Topics: Analysis of Variance; Animals; Autoradiography; Cell Transplantation; Cocaine; Corpus Striatum; Disease Models, Animal; Dopamine Uptake Inhibitors; Extremities; Functional Laterality; Humans; Male; Motor Neuron Disease; Parkinson Disease; Pigment Epithelium of Eye; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Time Factors; Transplantation, Heterologous

2007
Long-term methamphetamine administration in the vervet monkey models aspects of a human exposure: brain neurotoxicity and behavioral profiles.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008, Volume: 33, Issue:6

    Topics: Analysis of Variance; Animals; Autoradiography; Behavior, Animal; Benzazepines; Brain; Brain Chemistry; Central Nervous System Stimulants; Chlorocebus aethiops; Cocaine; Disease Models, Animal; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Methamphetamine; Neurotoxicity Syndromes; Protein Binding; Raclopride; Social Behavior; Tritium

2008
Chronic cocaine reduces RGS4 mRNA in rat prefrontal cortex and dorsal striatum.
    Neuroreport, 2007, Aug-06, Volume: 18, Issue:12

    Topics: Animals; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Down-Regulation; Drug Administration Schedule; Male; Neostriatum; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, G-Protein-Coupled; Recurrence; RGS Proteins; RNA, Messenger; Self Administration; Substance Withdrawal Syndrome

2007
Behavioral expression of cocaine sensitization in rats is accompanied by a distinct pattern of modifications in the PKA/DARPP-32 signaling pathway.
    Journal of neurochemistry, 2007, Volume: 103, Issue:3

    Topics: Animals; Behavior, Animal; Brain; Cocaine; Cocaine-Related Disorders; Cyclic AMP-Dependent Protein Kinases; Cyclin-Dependent Kinase 5; Disease Models, Animal; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Nucleus Accumbens; Phosphorylation; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Up-Regulation

2007
Drugs of abuse specifically sensitize noradrenergic and serotonergic neurons via a non-dopaminergic mechanism.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008, Volume: 33, Issue:7

    Topics: Animals; Behavior, Animal; Brain Chemistry; Cocaine; Disease Models, Animal; Dopamine; Dopamine Agents; Drug Administration Schedule; Drug Interactions; Ethanol; Male; Mice; Mice, Inbred C57BL; Morphine; Motor Activity; Neurons; Norepinephrine; p-Chloroamphetamine; Serotonin; Serotonin Agents; Substance-Related Disorders

2008
Levo-tetrahydropalmatine inhibits cocaine's rewarding effects: experiments with self-administration and brain-stimulation reward in rats.
    Neuropharmacology, 2007, Volume: 53, Issue:6

    Topics: Animals; Antipsychotic Agents; Behavior, Animal; Berberine Alkaloids; Brain; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Drug Antagonism; Male; Microdialysis; Nucleus Accumbens; Rats; Rats, Long-Evans; Reinforcement Schedule; Reward; Self Administration; Stereoisomerism

2007
Anxiogenic effects of cocaine withdrawal in zebrafish.
    Physiology & behavior, 2008, Jan-28, Volume: 93, Issue:1-2

    Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Cocaine; Diazepam; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Hyperkinesis; Male; Motor Activity; Statistics, Nonparametric; Stereotyped Behavior; Substance Withdrawal Syndrome; Time Factors; Zebrafish

2008
DeltaFosB induction in orbitofrontal cortex mediates tolerance to cocaine-induced cognitive dysfunction.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Sep-26, Volume: 27, Issue:39

    Topics: Animals; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Cognition Disorders; Disease Models, Animal; Drug Tolerance; Frontal Lobe; Gene Expression Profiling; Gene Transfer Techniques; Male; Neuropsychological Tests; Oligonucleotide Array Sequence Analysis; Proto-Oncogene Proteins c-fos; Rats; Rats, Long-Evans; Rats, Sprague-Dawley

2007
A role for conditioned ventral tegmental glutamate release in cocaine seeking.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Sep-26, Volume: 27, Issue:39

    Topics: Animals; Behavior, Addictive; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Disease Models, Animal; Dopamine Uptake Inhibitors; gamma-Aminobutyric Acid; Glutamic Acid; Male; Microdialysis; Rats; Rats, Long-Evans; Reinforcement, Psychology; Ventral Tegmental Area

2007
Cell surface AMPA receptors in the rat nucleus accumbens increase during cocaine withdrawal but internalize after cocaine challenge in association with altered activation of mitogen-activated protein kinases.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Sep-26, Volume: 27, Issue:39

    Topics: Animals; Central Nervous System Agents; Cocaine; Disease Models, Animal; Male; Mitogen-Activated Protein Kinases; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Cell Surface; Substance Withdrawal Syndrome

2007
Metabolic-dopaminergic mapping of the 6-hydroxydopamine rat model for Parkinson's disease.
    European journal of nuclear medicine and molecular imaging, 2008, Volume: 35, Issue:1

    Topics: Animals; Behavior, Animal; Cocaine; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Fluorodeoxyglucose F18; Glucose; Humans; Oxidopamine; Parkinson Disease; Positron-Emission Tomography; Rats; Rats, Wistar; Tyrosine 3-Monooxygenase

2008
Decreased withdrawal symptoms but normal tolerance to nicotine in mice null for the alpha7 nicotinic acetylcholine receptor subunit.
    Neuropharmacology, 2007, Volume: 53, Issue:7

    Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Analysis of Variance; Anesthetics, Local; Animals; Behavior, Animal; Cocaine; Disease Models, Animal; Drug Tolerance; Exploratory Behavior; Female; Male; Maze Learning; Mecamylamine; Mice; Mice, Inbred C57BL; Mice, Knockout; Nicotinic Antagonists; Receptors, Nicotinic; Substance Withdrawal Syndrome

2007
Role of the prelimbic cortex in the acquisition, re-acquisition or persistence of responding for a drug-paired conditioned reinforcer.
    Neuroscience, 2007, Dec-05, Volume: 150, Issue:2

    Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Denervation; Disease Models, Animal; Dopamine Uptake Inhibitors; GABA Agonists; Limbic System; Male; Neural Pathways; Prefrontal Cortex; Rats; Reinforcement, Psychology; Substance-Related Disorders

2007
Regional differences in the effects of withdrawal from repeated cocaine upon Homer and glutamate receptor expression: a two-species comparison.
    Brain research, 2007, Dec-12, Volume: 1184

    Topics: Animals; Brain; Carrier Proteins; Cocaine; Disease Models, Animal; Drug Administration Schedule; Gene Expression Regulation; Homer Scaffolding Proteins; Male; Mice; Mice, Inbred C57BL; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Substance Withdrawal Syndrome

2007
VMAT2 and dopamine neuron loss in a primate model of Parkinson's disease.
    Journal of neurochemistry, 2008, Volume: 105, Issue:1

    Topics: Animals; Autoradiography; Brain; Carbon Isotopes; Carrier Proteins; Cocaine; Disease Models, Animal; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Glial Fibrillary Acidic Protein; Isoquinolines; Male; Neurons; Papio anubis; Parkinsonian Disorders; Positron-Emission Tomography; Raclopride; Tetrabenazine; Tyrosine 3-Monooxygenase; Vesicular Monoamine Transport Proteins

2008
Histone deacetylase 5 epigenetically controls behavioral adaptations to chronic emotional stimuli.
    Neuron, 2007, Nov-08, Volume: 56, Issue:3

    Topics: Acetylation; Adaptation, Physiological; Animals; Chromatin; Chronic Disease; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Emotions; Epigenesis, Genetic; Gene Expression Regulation, Enzymologic; Histone Deacetylases; Histones; Mice; Mice, Inbred C57BL; Nucleus Accumbens; Reward; Stress, Psychological

2007
Cocaine-conditioned place preference by dopamine-deficient mice is mediated by serotonin.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Nov-14, Volume: 27, Issue:46

    Topics: Animals; Brain; Brain Chemistry; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Disease Models, Animal; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine Uptake Inhibitors; Female; Fluoxetine; Male; Mice; Mice, Knockout; Mice, Transgenic; Receptors, Dopamine D1; Receptors, Dopamine D2; Reward; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Synaptic Transmission

2007
Chronic valproate normalizes behavior in mice overexpressing calcineurin.
    European journal of pharmacology, 2008, Feb-02, Volume: 580, Issue:1-2

    Topics: Animals; Antimanic Agents; Behavior, Animal; Calcineurin; Cocaine; Disease Models, Animal; Gene Expression; Maze Learning; Mice; Mice, Transgenic; Mood Disorders; Motor Activity; Phosphorylation; Valproic Acid

2008
Extended access to cocaine self-administration produces long-lasting prefrontal cortex-dependent working memory impairments.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008, Volume: 33, Issue:10

    Topics: Animals; Cell Death; Chronic Disease; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug Administration Schedule; Male; Memory Disorders; Memory, Short-Term; Nerve Degeneration; Neural Pathways; Neurons; Neurotoxins; Oligodendroglia; Prefrontal Cortex; Rats; Rats, Wistar; Self Administration; Time

2008
KATP channels confer survival advantage in cocaine overdose.
    Molecular psychiatry, 2007, Volume: 12, Issue:12

    Topics: Animals; Behavior, Animal; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug Overdose; Membrane Transport Modulators; Mice; Mice, Knockout; Pinacidil; Potassium Channels, Inwardly Rectifying

2007
Alpha1-adrenergic receptor-induced heterosynaptic long-term depression in the bed nucleus of the stria terminalis is disrupted in mouse models of affective disorders.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008, Volume: 33, Issue:10

    Topics: Adrenergic alpha-Agonists; Animals; Brain Chemistry; Calcium Channels, L-Type; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Glutamic Acid; Long-Term Synaptic Depression; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mood Disorders; Neural Pathways; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Organ Culture Techniques; Patch-Clamp Techniques; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Glutamate; Septal Nuclei; Synaptic Transmission

2008
Progesterone attenuates cocaine-induced conditioned place preference in female rats.
    Brain research, 2008, Jan-16, Volume: 1189

    Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Disease Models, Animal; Female; Learning; Memory Disorders; Menstrual Cycle; Neuropsychological Tests; Progesterone; Rats; Rats, Inbred F344; Recognition, Psychology; Recurrence; Reward; Sex Characteristics

2008
The effect of amiodarone pretreatment on survival of mice with cocaine toxicity.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2005, Volume: 1, Issue:1

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Cocaine; Disease Models, Animal; Drug Antagonism; Injections, Intraperitoneal; Longevity; Male; Mice; Mice, Inbred Strains; Poisoning; Seizures; Substance-Related Disorders; Vasoconstrictor Agents

2005
Embryotoxicity of serum from women smoking cocaine base paste (CBP).
    European journal of obstetrics, gynecology, and reproductive biology, 2008, Volume: 139, Issue:1

    Topics: Adult; Animals; Case-Control Studies; Chromosome Aberrations; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Embryo Culture Techniques; Embryonic Development; Female; Humans; Mice; Pregnancy; Teratogens

2008
Norepinephrine signaling through beta-adrenergic receptors is critical for expression of cocaine-induced anxiety.
    Biological psychiatry, 2008, Jun-01, Volume: 63, Issue:11

    Topics: Adrenergic beta-Antagonists; Animals; Anxiety; Behavior, Animal; Cocaine; Disease Models, Animal; Disulfiram; Dopamine beta-Hydroxylase; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Male; Maze Learning; Mice; Mice, Knockout; Norepinephrine; Propranolol; Receptors, Adrenergic, beta; Signal Transduction

2008
The kappa-opioid receptor antagonist nor-BNI inhibits cocaine and amphetamine, but not cannabinoid (WIN 52212-2), abstinence-induced withdrawal in planarians: an instance of 'pharmacologic congruence'.
    Brain research, 2008, Feb-08, Volume: 1193

    Topics: Amphetamine; Analgesics; Analysis of Variance; Animals; Behavior, Animal; Benzoxazines; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug Interactions; Morpholines; Naltrexone; Naphthalenes; Narcotic Antagonists; Planarians; Substance Withdrawal Syndrome; Time Factors

2008
Use of antipsychotics to treat cocaine toxicity?
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2008, Volume: 15, Issue:1

    Topics: Animals; Antipsychotic Agents; Cocaine; Cocaine-Related Disorders; Diazepam; Disease Models, Animal; Mice; Piperazines; Thiazoles; Treatment Outcome

2008
Heightened drug-seeking motivation following extended daily access to self-administered cocaine.
    Progress in neuro-psychopharmacology & biological psychiatry, 2008, Apr-01, Volume: 32, Issue:3

    Topics: Analysis of Variance; Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Disease Models, Animal; Dopamine Uptake Inhibitors; Male; Maze Learning; Motivation; Rats; Rats, Sprague-Dawley; Self Administration; Time Factors

2008
Drug-induced activation of dopamine D(1) receptor signaling and inhibition of class I/II histone deacetylase induce chromatin remodeling in reward circuitry and modulate cocaine-related behaviors.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008, Volume: 33, Issue:12

    Topics: Acetylation; Animals; Brain; Brain Chemistry; Brain-Derived Neurotrophic Factor; Chromatin Assembly and Disassembly; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine; Dopamine Agonists; Dopamine Uptake Inhibitors; Enzyme Inhibitors; Histone Deacetylase 1; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Male; Mice; Mice, Inbred C57BL; Receptors, Dopamine D1; Reward; Signal Transduction; Synaptic Transmission; Tyrosine 3-Monooxygenase

2008
Persistent alterations in cognitive function and prefrontal dopamine D2 receptors following extended, but not limited, access to self-administered cocaine.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008, Volume: 33, Issue:12

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Cognition Disorders; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Male; Mice; Mice, Inbred C57BL; Neural Pathways; Neurons; Prefrontal Cortex; Receptors, Dopamine D1; Receptors, Dopamine D2; RNA, Messenger; Self Administration; Synaptic Transmission

2008
Nucleus accumbens core acetylcholine is preferentially activated during acquisition of drug- vs food-reinforced behavior.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008, Volume: 33, Issue:13

    Topics: Acetylcholine; Animals; Cholinergic Antagonists; Cocaine; Conditioning, Psychological; Disease Models, Animal; Dopamine; Feeding Behavior; Learning; Male; Morphine; Nucleus Accumbens; Piperidines; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, Cholinergic; Reinforcement, Psychology; Remifentanil; Substance-Related Disorders; Synaptic Transmission

2008
Neurokinin B/NK3 receptors exert feedback inhibition on L-DOPA actions in the 6-OHDA lesion rat model of Parkinson's disease.
    Neuropharmacology, 2008, Volume: 54, Issue:7

    Topics: Animals; Antiparkinson Agents; Autoradiography; Behavior, Animal; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cocaine; Disease Models, Animal; Dopamine; Feedback; Functional Laterality; Gene Expression Regulation; Levodopa; Oxidopamine; Parkinson Disease; Peptide Fragments; Quinolines; Radioisotopes; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-3; Serine; Substance P; Sympatholytics; Tyrosine 3-Monooxygenase

2008
Cocaine exposure during the early postnatal period diminishes medial frontal cortex Gs coupling to dopamine D1-like receptors in adult rat.
    Neuroscience letters, 2008, Jun-20, Volume: 438, Issue:2

    Topics: Aging; Animals; Animals, Newborn; Cell Membrane; Cocaine; Cocaine-Related Disorders; Cognition; Cognition Disorders; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Female; Frontal Lobe; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Male; Memory, Short-Term; Mental Disorders; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, G-Protein-Coupled; Signal Transduction; Synaptic Transmission; Time

2008
The glutamatergic projection from the prefrontal cortex to the nucleus accumbens core is required for cocaine-induced decreases in ventral pallidal GABA.
    Neuroscience letters, 2008, Jun-20, Volume: 438, Issue:2

    Topics: Animals; Basal Ganglia; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Extracellular Fluid; GABA Agonists; gamma-Aminobutyric Acid; Globus Pallidus; Glutamic Acid; Male; Microdialysis; Neural Pathways; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Synaptic Transmission

2008
Involvement of extracellular signal-regulated protein kinase in acute cocaine-induced c-fos in nucleus accumbens.
    Neuroscience letters, 2008, Jun-20, Volume: 438, Issue:2

    Topics: Animals; Cell Count; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Down-Regulation; Drug Administration Schedule; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Fluorescent Antibody Technique; Male; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 3; Neurons; Nucleus Accumbens; Proto-Oncogene Proteins c-fos

2008
Impulsive choice as a predictor of acquisition of IV cocaine self- administration and reinstatement of cocaine-seeking behavior in male and female rats.
    Experimental and clinical psychopharmacology, 2008, Volume: 16, Issue:2

    Topics: Animals; Behavior, Animal; Choice Behavior; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Disease Models, Animal; Dopamine Uptake Inhibitors; Female; Impulsive Behavior; Male; Motor Activity; Rats; Rats, Wistar; Reaction Time; Reinforcement, Psychology; Self Administration; Sex Characteristics

2008
Schedule-induced self injection of drugs.
    Progress in neuro-psychopharmacology & biological psychiatry, 1984, Volume: 8, Issue:1

    Topics: Alcoholism; Animals; Cocaine; Conditioning, Operant; Corticosterone; Disease Models, Animal; Heroin Dependence; Humans; Nicotine; Nucleus Accumbens; Rats; Reinforcement Schedule; Substance-Related Disorders

1984
[Formation of nicotine addiction in mongrel white rats].
    Biulleten' eksperimental'noi biologii i meditsiny, 1984, Volume: 98, Issue:11

    Topics: Animals; Cocaine; Disease Models, Animal; Dose-Response Relationship, Drug; Drinking; Humans; Male; Nicotine; Rats; Substance-Related Disorders; Time Factors

1984
Coping and the stress-induced potentiation of stimulant stereotypy in the rat.
    Science (New York, N.Y.), 1983, Mar-04, Volume: 219, Issue:4588

    Topics: Animals; Cocaine; Dextroamphetamine; Disease Models, Animal; Drug Synergism; Humans; Rats; Schizophrenia; Stereotyped Behavior; Stress, Physiological

1983
Measures of cocaine-seeking behavior using a multiple schedule of food and drug self-administration in rats.
    Drug and alcohol dependence, 1995, Volume: 38, Issue:3

    Topics: Animals; Appetitive Behavior; Association Learning; Cocaine; Conditioning, Operant; Disease Models, Animal; Extinction, Psychological; Humans; Male; Motivation; Narcotics; Rats; Rats, Wistar; Reinforcement Schedule; Self Administration; Substance-Related Disorders

1995
A primate model of polydrug abuse: cocaine and heroin combinations.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 274, Issue:3

    Topics: Animals; Azocines; Cocaine; Discrimination Learning; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Food; Heroin; Macaca mulatta; Male; Narcotic Antagonists; Narcotics; Self Administration; Substance-Related Disorders

1995
The rabbit as a model for studies of cocaine exposure in utero.
    Laboratory animal science, 1995, Volume: 45, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Body Weight; Brain; Cocaine; Disease Models, Animal; Embryonic and Fetal Development; Female; Injections, Intravenous; Male; Pregnancy; Prenatal Exposure Delayed Effects; Rabbits; Time Factors

1995
Cocaine binges differentially alter striatal preprodynorphin and zif/268 mRNAs.
    Brain research. Molecular brain research, 1995, Volume: 29, Issue:2

    Topics: Analysis of Variance; Animals; Behavior, Animal; Cocaine; Corpus Striatum; Disease Models, Animal; DNA-Binding Proteins; Drug Administration Schedule; Dynorphins; Early Growth Response Protein 1; Enkephalins; Immediate-Early Proteins; Male; Nerve Tissue Proteins; Protein Precursors; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; RNA, Messenger; Transcription Factors

1995
Interactions between chronic haloperidol treatment and cocaine in rats: an animal model of intermittent cocaine use in neuroleptic treated populations.
    Psychopharmacology, 1993, Volume: 110, Issue:4

    Topics: Animals; Behavior, Animal; Cocaine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Female; Haloperidol; Motor Activity; Rats; Receptors, Presynaptic; Stereotyped Behavior; Substance-Related Disorders

1993
Food deprivation history and cocaine self-administration: an animal model of binge eating.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 48, Issue:4

    Topics: Aging; Animals; Butorphanol; Cocaine; Conditioning, Operant; Disease Models, Animal; Female; Food Deprivation; Hyperphagia; Injections, Intravenous; Rats; Rats, Sprague-Dawley; Self Administration

1994
Maternal cocaine abuse resulting in necrotizing enterocolitis--an experimental study in a rat model.
    Acta paediatrica (Oslo, Norway : 1992). Supplement, 1994, Volume: 396

    Topics: Animals; Animals, Newborn; Cocaine; Disease Models, Animal; Dose-Response Relationship, Drug; Enterocolitis, Pseudomembranous; Female; Fetal Diseases; Placenta; Pregnancy; Pregnancy, Animal; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Substance-Related Disorders

1994
Effect of cocaine and murine AIDS on lamina propria T and B cells in normal mice.
    Life sciences, 1994, Volume: 54, Issue:9

    Topics: Animals; B-Lymphocytes; CD4 Antigens; Cocaine; Disease Models, Animal; Female; Immunoglobulin A; Intestinal Mucosa; Lymphoid Tissue; Mice; Mice, Inbred C57BL; Murine Acquired Immunodeficiency Syndrome; T-Lymphocytes

1994
Cocaine facilitation of cryptosporidiosis by murine AIDS in male and female C57/BL/6 mice.
    Advances in experimental medicine and biology, 1993, Volume: 335

    Topics: Animals; Cocaine; Cryptosporidiosis; Cryptosporidium; Disease Models, Animal; Feces; Female; Male; Mice; Mice, Inbred C57BL; Murine Acquired Immunodeficiency Syndrome; Organ Size; Retroviridae; Spleen

1993
Inhibitory effects of ibogaine on cocaine self-administration in rats.
    European journal of pharmacology, 1993, Sep-14, Volume: 241, Issue:2-3

    Topics: Analysis of Variance; Animals; Brain; Cocaine; Disease Models, Animal; Drug Administration Schedule; Ibogaine; Male; Motor Activity; Rats; Rats, Wistar; Self Administration; Substance-Related Disorders

1993
Dissimilar patterns of degeneration in brain following four different addictive stimulants.
    Neuroreport, 1993, Oct-25, Volume: 5, Issue:1

    Topics: Animals; Brain; Cocaine; Dextroamphetamine; Disease Models, Animal; Drug Implants; Methamphetamine; Nerve Degeneration; Phencyclidine; Rats; Substance-Related Disorders

1993
Retinal hemorrhages associated with in utero exposure to cocaine. Experimental and clinical findings.
    Retina (Philadelphia, Pa.), 1996, Volume: 16, Issue:5

    Topics: Adult; Animals; Animals, Newborn; Cocaine; Disease Models, Animal; Female; Fundus Oculi; Humans; Infant, Newborn; Male; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Retinal Hemorrhage; Retinal Vessels; Substance-Related Disorders; Uterus

1996
Effect of insulin on norepinephrine overflow at peripheral sympathetic nerve endings in young spontaneously hypertensive rats.
    American journal of hypertension, 1996, Volume: 9, Issue:11

    Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Buffers; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Electric Stimulation; Enzyme Inhibitors; Hypertension; Insulin; Male; Nerve Endings; Norepinephrine; Ouabain; Potassium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium Chloride, Dietary; Sodium-Potassium-Exchanging ATPase; Sympathetic Nervous System; Yohimbine

1996
Time course of cocaine in rabbit hair.
    Forensic science international, 1997, Jan-17, Volume: 84, Issue:1-3

    Topics: Animals; Cocaine; Disease Models, Animal; Female; Gas Chromatography-Mass Spectrometry; Hair; Narcotics; Rabbits; Sensitivity and Specificity; Substance Abuse Detection

1997
Cortical and hippocampal EEG power spectra in animal models of schizophrenia produced with methamphetamine, cocaine, and phencyclidine.
    Psychopharmacology, 1997, Volume: 131, Issue:4

    Topics: Adrenergic Agents; Animals; Cerebral Cortex; Cocaine; Disease Models, Animal; Electroencephalography; Hallucinogens; Hippocampus; Male; Methamphetamine; Phencyclidine; Rabbits; Schizophrenia

1997
Quantitative autoradiographic measurement of cocaine-induced regional myocardial metabolic changes in hypertensive rats.
    Nuclear medicine and biology, 1994, Volume: 21, Issue:2

    Topics: Animals; Autoradiography; Cardiomyopathies; Cocaine; Disease Models, Animal; Heart; Humans; Hypertension; Myocardium; Narcotics; Rats; Rats, Sprague-Dawley; Risk Factors; Sodium Chloride, Dietary; Substance-Related Disorders

1994
Dopamine efflux studies into in vivo actions of psychostimulant drugs.
    Advances in pharmacology (San Diego, Calif.), 1998, Volume: 42

    Topics: Benzazepines; Central Nervous System Stimulants; Cocaine; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Antagonists; Exocytosis; Humans; Motor Activity; Receptors, Dopamine D1; Stereotyped Behavior; Substance-Related Disorders

1998
Development of a therapeutic vaccine for the treatment of cocaine addiction.
    Drug and alcohol dependence, 1997, Dec-15, Volume: 48, Issue:3

    Topics: Animals; Antigen-Antibody Complex; Behavior, Addictive; Blood-Brain Barrier; Brain Chemistry; Carrier Proteins; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Humans; Immunization, Passive; Mice; Rats; Self Medication; Serum Albumin, Bovine; Vaccines

1997
Prenatal cocaine alters normoxic sleep-wake and diaphragmatic EMG patterns in piglets.
    Pediatric pulmonology, 1998, Volume: 25, Issue:1

    Topics: Age Factors; Animals; Animals, Newborn; Cocaine; Diaphragm; Disease Models, Animal; Electromyography; Female; Oxygen; Pregnancy; Prenatal Exposure Delayed Effects; Respiratory Mechanics; Sleep Stages; Swine

1998
The effects of lithium on a potential cycling model of bipolar disorder.
    Progress in neuro-psychopharmacology & biological psychiatry, 1998, Volume: 22, Issue:3

    Topics: Amphetamine; Animals; Antipsychotic Agents; Bipolar Disorder; Cocaine; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Drug Therapy, Combination; Lithium; Male; Models, Biological; Nucleus Accumbens; Pain; Rats; Rats, Sprague-Dawley; Stress, Psychological

1998
Transient amelioration of the sensitization of cocaine-induced behaviors in rats by the induction of tolerance.
    Brain research, 1998, Jun-22, Volume: 797, Issue:1

    Topics: Animals; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug Tolerance; Humans; Infant; Male; Osmotic Pressure; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Substance Withdrawal Syndrome; Substance-Related Disorders

1998
Effects of dopaminergic drugs, occlusal disharmonies, and chronic stress on non-functional masticatory activity in the rat, assessed by incisal attrition.
    Journal of dental research, 1998, Volume: 77, Issue:6

    Topics: Analysis of Variance; Animals; Apomorphine; Bruxism; Cocaine; Dental Occlusion, Traumatic; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Dopamine Uptake Inhibitors; Haloperidol; Incisor; Male; Masticatory Muscles; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Stress, Physiological; Tooth Attrition

1998
A mouse model of transplacental cocaine exposure. Clinical implications for exposed infants and children.
    Annals of the New York Academy of Sciences, 1998, Jun-21, Volume: 846

    Topics: Animals; Association Learning; Brain; Child; Cocaine; Conditioning, Classical; Disease Models, Animal; Embryonic and Fetal Development; Female; Gestational Age; Growth; Humans; Infant; Mice; Nutrition Disorders; Phentolamine; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Substance-Related Disorders

1998
A catalytic antibody against cocaine prevents cocaine's reinforcing and toxic effects in rats.
    Proceedings of the National Academy of Sciences of the United States of America, 1998, Aug-18, Volume: 95, Issue:17

    Topics: Animals; Antibodies, Catalytic; Antibodies, Monoclonal; Cocaine; Disease Models, Animal; Hydrolysis; Male; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration; Substance-Related Disorders

1998
The effects of cocaine, amphetamine, and the dopamine D1 receptor agonist SKF 38393 on fear extinction as measured with potentiated startle: implications for psychomotor stimulant psychosis.
    Behavioral neuroscience, 1998, Volume: 112, Issue:4

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Acoustic Stimulation; Analysis of Variance; Animals; Central Nervous System Stimulants; Cocaine; Conditioning, Classical; Dextroamphetamine; Disease Models, Animal; Dopamine Agonists; Electroshock; Extinction, Psychological; Fear; Male; Motor Activity; Psychoses, Substance-Induced; Rats; Rats, Wistar; Reflex, Startle

1998
Comparison between the decrease of dopamine transporter and that of L-DOPA uptake for detection of early to advanced stage of Parkinson's disease in animal models.
    Synapse (New York, N.Y.), 1999, Mar-01, Volume: 31, Issue:3

    Topics: Animals; Biological Transport; Brain; Carrier Proteins; Cocaine; Disease Models, Animal; Dopa Decarboxylase; Dopamine Plasma Membrane Transport Proteins; Female; Gene Expression Regulation; Levodopa; Membrane Glycoproteins; Membrane Transport Proteins; Motor Activity; Nerve Tissue Proteins; Neuropeptides; Parkinson Disease, Secondary; Radioligand Assay; Rats; Rats, Wistar; Rotation; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins

1999
Effects of contingent and non-contingent cocaine on drug-seeking behavior measured using a second-order schedule of cocaine reinforcement in rats.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1999, Volume: 20, Issue:6

    Topics: Analysis of Variance; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Disease Models, Animal; Male; Psychomotor Performance; Rats; Reinforcement, Psychology; Self Administration

1999
Dopamine imaging markers and predictive mathematical models for progressive degeneration in Parkinson's disease.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1999, Volume: 53, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Aged; Animals; Biomarkers; Cocaine; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Haplorhini; Humans; Macaca fascicularis; Magnetic Resonance Imaging; Male; Models, Biological; Parkinson Disease; Tomography, Emission-Computed; Visual Cortex

1999
Behavioral effects of cocaine on a transgenic mouse model of cortical-limbic compulsion.
    Brain research, 1999, Jul-03, Volume: 833, Issue:2

    Topics: Animals; Cerebral Cortex; Cholera Toxin; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Female; Gene Expression; Glutamic Acid; Humans; Limbic System; Mice; Mice, Inbred BALB C; Mice, Transgenic; Obsessive-Compulsive Disorder; Receptors, Dopamine D1; Stereotyped Behavior; Transgenes

1999
5-HT receptor knockout mice: pharmacological tools or models of psychiatric disorders.
    Annals of the New York Academy of Sciences, 1999, Apr-30, Volume: 868

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aggression; Animals; Behavior, Animal; Cocaine; Disease Models, Animal; Dopamine; Dopamine Antagonists; Feeding Behavior; gamma-Aminobutyric Acid; Indoles; Mental Disorders; Mice; Mice, Knockout; N-Methyl-3,4-methylenedioxyamphetamine; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Substance-Related Disorders

1999
Preclinical evaluation of newly approved and potential antiepileptic drugs against cocaine-induced seizures.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 290, Issue:3

    Topics: Animals; Anticonvulsants; Behavior, Animal; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Male; Mice; Motor Activity; Seizures

1999
Brain damage and hypoxia in an ovine fetal chronic cocaine model.
    European journal of obstetrics, gynecology, and reproductive biology, 1999, Volume: 86, Issue:1

    Topics: Animals; Apoptosis; Brain Damage, Chronic; Cell Nucleus; Cocaine; Cytoplasm; Disease Models, Animal; Female; Fetal Hypoxia; Glial Fibrillary Acidic Protein; Microscopy, Electron; Neurons; Pregnancy; Sheep

1999
Reinstatement of cocaine self-administration in rats: sex differences.
    Psychopharmacology, 2000, Volume: 148, Issue:2

    Topics: Analysis of Variance; Animals; Behavior, Animal; Cocaine; Disease Models, Animal; Dose-Response Relationship, Drug; Extinction, Psychological; Female; Infusions, Intravenous; Male; Rats; Rats, Wistar; Recurrence; Self Administration; Sex Factors; Substance-Related Disorders

2000
Dissociation of primary and secondary reward-relevant limbic nuclei in an animal model of relapse.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2000, Volume: 22, Issue:5

    Topics: Amygdala; Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Infusion Pumps, Implantable; Limbic System; Male; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Recurrence; Reward; Self Administration; Sodium Channels; Tetrodotoxin

2000
Coronary vascular responses to short-term cocaine administration in conscious baboons compared with dogs.
    Journal of the American College of Cardiology, 2000, Volume: 35, Issue:5

    Topics: Animals; Cocaine; Consciousness; Coronary Circulation; Coronary Vessels; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Female; Hemodynamics; Injections, Intravenous; Male; Myocardial Ischemia; Myocardium; Narcotics; Oxygen Consumption; Papio; Splenectomy; Vasoconstrictor Agents

2000
Predicting relapse to cocaine-seeking behavior: a multiple regression approach.
    Behavioural pharmacology, 1999, Volume: 10, Issue:5

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Classical; Disease Models, Animal; Extinction, Psychological; Male; Motivation; Motor Activity; Rats; Rats, Sprague-Dawley; Regression Analysis; Reinforcement Schedule; Self Administration

1999
Effects of oligonucleotide antisense to dopamine D(1A) receptor messenger RNA in a rodent model of levodopa-induced dyskinesia.
    Neuroscience, 2000, Volume: 98, Issue:1

    Topics: Animals; Antiparkinson Agents; Apomorphine; Autoradiography; Behavior, Animal; Cocaine; Denervation; Disease Models, Animal; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dyskinesia, Drug-Induced; Gene Expression; Levodopa; Male; Oligonucleotides, Antisense; Oxidopamine; Phenotype; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; RNA, Messenger; Rotation; Substantia Nigra; Sympatholytics; Tritium

2000
A rodent model of cocaine abstinence syndrome.
    Pharmacology, biochemistry, and behavior, 2000, Volume: 66, Issue:2

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Humans; Infant, Newborn; Infusion Pumps, Implantable; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Syndrome

2000
Dopamine D3 receptor agents as potential new medications for drug addiction.
    European psychiatry : the journal of the Association of European Psychiatrists, 2000, Volume: 15, Issue:2

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Drug Synergism; Locomotion; Naphthalenes; Neurons; Nucleus Accumbens; Pyrrolidines; Rats; Receptors, Dopamine; Reward

2000
Relationship between cocaine-induced hepatotoxic neurobehavioral & biochemical changes in mice: the antidotal effects of buprenorphine.
    Life sciences, 2000, May-26, Volume: 67, Issue:1

    Topics: Adenosine Triphosphate; Alanine Transaminase; Animals; Antidotes; Behavior, Animal; Brain; Buprenorphine; Cocaine; Disease Models, Animal; Hepatic Encephalopathy; Liver; Mice; Mice, Inbred ICR; Motor Activity; Narcotic Antagonists; Narcotics

2000
Glutamate transmission in the nucleus accumbens mediates relapse in cocaine addiction.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000, Aug-01, Volume: 20, Issue:15

    Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Extinction, Psychological; Glutamic Acid; Male; Microinjections; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Dopamine; Receptors, N-Methyl-D-Aspartate; Recurrence; Self Administration; Synaptic Transmission

2000
Dopamine D1- and D2-like receptor mechanisms in relapse to cocaine-seeking behavior: effects of selective antagonists and agonists.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 294, Issue:2

    Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Classical; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Male; Receptors, Dopamine D1; Receptors, Dopamine D2; Saimiri; Self Administration

2000
Acute and chronic dopamine dynamics in a nonhuman primate model of recreational cocaine use.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000, Sep-15, Volume: 20, Issue:18

    Topics: Acute Disease; Analysis of Variance; Animals; Behavior, Animal; Chronic Disease; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Disease Models, Animal; Dopamine; Drug Tolerance; Extracellular Space; Macaca mulatta; Male; Microdialysis; Regression Analysis; Self Administration; Synaptic Transmission

2000
Deficits in striatal dopamine D(2) receptors and energy metabolism detected by in vivo microPET imaging in a rat model of Huntington's disease.
    Experimental neurology, 2000, Volume: 166, Issue:2

    Topics: Animals; Autoradiography; Benzazepines; Cocaine; Corpus Striatum; Disease Models, Animal; Dopamine Antagonists; Dopamine Uptake Inhibitors; Energy Metabolism; Female; Fluorodeoxyglucose F18; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Huntington Disease; In Situ Hybridization; Nerve Degeneration; Neurotoxins; Quinolinic Acid; Radioligand Assay; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; RNA, Messenger; Spiperone; Substantia Nigra; Tomography, Emission-Computed; Tritium

2000
CB1 cannabinoid receptor agonist WIN 55,212-2 decreases intravenous cocaine self-administration in rats.
    Behavioural brain research, 1999, Volume: 104, Issue:1-2

    Topics: Animals; Benzoxazines; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Antagonism; Injections, Intravenous; Male; Morpholines; Naphthalenes; Piperidines; Pyrazoles; Rats; Rats, Long-Evans; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Self Administration

1999
Response requirements and unit dose modify the effects of GBR 12909 on cocaine-maintained behavior.
    Experimental and clinical psychopharmacology, 2000, Volume: 8, Issue:4

    Topics: Animals; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Female; Macaca mulatta; Male; Piperazines

2000
Anxiogenic-like effects limit rewarding effects of cocaine in balb/cbyj mice.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2001, Volume: 24, Issue:3

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Brain; Caudate Nucleus; Cocaine; Conditioning, Operant; Diazepam; Disease Models, Animal; Dopamine Antagonists; Dose-Response Relationship, Drug; Injections, Intravenous; Male; Mice; Mice, Inbred BALB C; Nucleus Accumbens; Reinforcement, Psychology; Self Administration; Substance-Related Disorders; Sulpiride

2001
Acute cocaine-induced seizures: differential sensitivity of six inbred mouse strains.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2001, Volume: 24, Issue:3

    Topics: Animals; Brain; Cerebral Cortex; Cocaine; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Female; Genetic Predisposition to Disease; Hippocampus; Kainic Acid; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Seizures

2001
Effects of the kappa-opioid receptor agonist, U69593, on the development of sensitization and on the maintenance of cocaine self-administration.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2001, Volume: 24, Issue:4

    Topics: Animals; Behavior, Addictive; Behavior, Animal; Benzeneacetamides; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Disease Models, Animal; Drug Administration Schedule; Injections, Intravenous; Male; Photic Stimulation; Pyrrolidines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Opioid, kappa; Reinforcement, Psychology; Self Administration

2001
Cocaine, ethanol, and cocaethylene cardiotoxity in an animal model of cocaine and ethanol abuse.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2001, Volume: 8, Issue:3

    Topics: Alcoholism; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Cardiac Output; Cardiomyopathies; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dogs; Electrocardiography; Ethanol; Prospective Studies; Randomized Controlled Trials as Topic; Time Factors; Ventricular Pressure

2001
The effect of gamma-vinyl-GABA on the consumption of concurrently available oral cocaine and ethanol in the rat.
    Pharmacology, biochemistry, and behavior, 2001, Volume: 68, Issue:2

    Topics: Alcohol Drinking; Animals; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Male; Rats; Rats, Wistar; Self Administration; Vigabatrin

2001
Effect of MPTP-induced denervation on basal ganglia GABA(B) receptors: correlation with dopamine concentrations and dopamine transporter.
    Synapse (New York, N.Y.), 2001, Jun-01, Volume: 40, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Basal Ganglia; Benzoates; Cocaine; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Female; Macaca fascicularis; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Organophosphorus Compounds; Parkinsonian Disorders; Protein Subunits; Radioligand Assay; Receptors, GABA-B; RNA, Messenger; Substantia Nigra; Subthalamic Nucleus

2001
Progression of changes in dopamine transporter binding site density as a result of cocaine self-administration in rhesus monkeys.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Apr-15, Volume: 21, Issue:8

    Topics: Animals; Autoradiography; Binding Sites; Carrier Proteins; Caudate Nucleus; Chronic Disease; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Densitometry; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Injections, Intravenous; Macaca mulatta; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Nucleus Accumbens; Putamen; Self Administration; Tissue Distribution

2001
Glial cell line-derived neurotrophic factor (GDNF) gene delivery protects dopaminergic terminals from degeneration.
    Experimental neurology, 2001, Volume: 169, Issue:1

    Topics: Aging; Animals; Autoradiography; Carrier Proteins; Cocaine; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Genetic Therapy; Genetic Vectors; Glial Cell Line-Derived Neurotrophic Factor; Male; Membrane Glycoproteins; Membrane Transport Proteins; Microinjections; Motor Activity; Nerve Growth Factors; Nerve Tissue Proteins; Neurons; Neurotransmitter Agents; Oxidopamine; Parkinson Disease, Secondary; Presynaptic Terminals; Rats; Rats, Inbred F344; RNA, Messenger; Substantia Nigra; Tyrosine 3-Monooxygenase

2001
A shot against cocaine addiction.
    Lab animal, 2001, Volume: 30, Issue:4

    Topics: Animals; Antibodies; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Immunization, Passive; Locomotion; Rats; Vaccination

2001
Vulnerability of 125I-alpha-conotoxin MII binding sites to nigrostriatal damage in monkey.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Aug-01, Volume: 21, Issue:15

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Autoradiography; Binding Sites; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Carrier Proteins; Cocaine; Conotoxins; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Habenula; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mesencephalon; Nerve Tissue Proteins; Neural Pathways; Neurons; Parkinson Disease, Secondary; Putamen; Pyridines; Receptors, Nicotinic; Saimiri; Substantia Nigra

2001
Drug-induced reinstatement to heroin and cocaine seeking: a rodent model of relapse in polydrug use.
    Experimental and clinical psychopharmacology, 2001, Volume: 9, Issue:3

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Extinction, Psychological; Heroin; Heroin Dependence; Infusions, Intravenous; Male; Narcotics; Rats; Rats, Long-Evans; Recurrence; Self Administration

2001
Cannabinoid activity curtails cocaine craving.
    Nature medicine, 2001, Volume: 7, Issue:10

    Topics: Animals; Cannabinoids; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dronabinol; Humans; Piperidines; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant

2001
A cannabinoid mechanism in relapse to cocaine seeking.
    Nature medicine, 2001, Volume: 7, Issue:10

    Topics: Animals; Behavior, Animal; Cannabinoid Receptor Modulators; Cannabinoids; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dronabinol; Humans; Piperidines; Pyrazoles; Rats; Rats, Long-Evans; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug; Recurrence; Rimonabant

2001
The circuitry mediating cocaine-induced reinstatement of drug-seeking behavior.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Nov-01, Volume: 21, Issue:21

    Topics: Animals; Behavior, Animal; Chronic Disease; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine; GABA Agonists; GABA-A Receptor Agonists; GABA-B Receptor Agonists; Globus Pallidus; Injections, Intraperitoneal; Male; Microinjections; Motor Activity; Nerve Net; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Recurrence; Reinforcement, Psychology; Self Administration; Ventral Tegmental Area

2001
Cocaine withdrawal in Planaria.
    European journal of pharmacology, 2001, Oct-26, Volume: 430, Issue:1

    Topics: Animals; Cocaine; Disease Models, Animal; Locomotion; Planarians; Temperature; Ultraviolet Rays

2001
Different requirements for cAMP response element binding protein in positive and negative reinforcing properties of drugs of abuse.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Dec-01, Volume: 21, Issue:23

    Topics: Alleles; Animals; Behavior, Animal; Brain; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Crosses, Genetic; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Disease Susceptibility; Drug Implants; Injections, Intraperitoneal; Mice; Mice, Inbred Strains; Mice, Mutant Strains; Morphine; Morphine Dependence; Motivation; Motor Activity; Narcotic Antagonists; Phenotype; Protein Isoforms; Reinforcement, Psychology; Response Elements; Spatial Behavior

2001
Cocaine enhances myocarditis induced by encephalomyocarditis virus in murine model.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 282, Issue:3

    Topics: Adrenalectomy; Animals; Cardiovirus Infections; Cocaine; Disease Models, Animal; Disease Progression; Encephalomyocarditis virus; Heart; Injections, Intraperitoneal; Male; Mice; Mice, Inbred BALB C; Myocarditis; Myocardium; Norepinephrine; Survival; Time Factors

2002
The effect of nitric oxide synthesis inhibition on intravenous cocaine self-administration.
    Progress in neuro-psychopharmacology & biological psychiatry, 2002, Volume: 26, Issue:1

    Topics: Animals; Cocaine; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Long-Evans; Reward; Self Administration

2002
Brain lesions induced by chronic cocaine administration to rats.
    Progress in neuro-psychopharmacology & biological psychiatry, 2002, Volume: 26, Issue:1

    Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Male; Neurons; Organ Specificity; Rats; Rats, Wistar; Stereotyped Behavior

2002
Cocaine enhances human immunodeficiency virus replication in a model of severe combined immunodeficient mice implanted with human peripheral blood leukocytes.
    The Journal of infectious diseases, 2002, Mar-01, Volume: 185, Issue:5

    Topics: Animals; CD4-CD8 Ratio; Cocaine; Disease Models, Animal; HIV Infections; HIV-1; Humans; Leukocytes, Mononuclear; Mice; Mice, SCID; Transplantation, Heterologous; Virus Replication

2002
The rate of intravenous cocaine administration determines susceptibility to sensitization.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Apr-15, Volume: 22, Issue:8

    Topics: Animals; Apomorphine; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Disease Susceptibility; Dose-Response Relationship, Drug; Drug Tolerance; Injections, Intravenous; Male; Medial Forebrain Bundle; Microinjections; Motor Activity; Oxidopamine; Rats; Rats, Sprague-Dawley; Time Factors

2002
Chronic cocaine exposure alters carbon dioxide reactivity but does not affect cerebral blood flow autoregulation in anesthetized dogs.
    The Journal of trauma, 2002, Volume: 52, Issue:5

    Topics: Anesthesia, General; Animals; Blood Flow Velocity; Blood Gas Analysis; Brain Injuries; Carbon Dioxide; Cerebrovascular Circulation; Cocaine; Disease Models, Animal; Dogs; Homeostasis; Male; Ultrasonography, Doppler, Transcranial

2002
Stimulus-response functions of the lateral dorsal striatum and regulation of behavior studied in a cocaine maintenance/cue reinstatement model in rats.
    Psychopharmacology, 2002, Volume: 161, Issue:3

    Topics: Acoustic Stimulation; Anesthetics, Local; Animals; Association Learning; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Cues; Discrimination Learning; Disease Models, Animal; Dose-Response Relationship, Drug; Extinction, Psychological; Infusions, Intravenous; Lidocaine; Male; Photic Stimulation; Rats; Rats, Wistar; Reinforcement Schedule; Self Administration; Time Factors

2002
Neurobiological evidence for hedonic allostasis associated with escalating cocaine use.
    Nature neuroscience, 2002, Volume: 5, Issue:7

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Drug Administration Schedule; Drug Tolerance; Electric Stimulation; Electrodes, Implanted; Hypothalamus; Male; Rats; Rats, Wistar; Reaction Time; Regression Analysis; Reward; Self Administration; Sensory Thresholds

2002
Cocaine treatment increases extracellular cholecystokinin (CCK) in the nucleus accumbens shell of awake, freely moving rats, an effect that is enhanced in rats that are behaviorally sensitized to cocaine.
    Journal of neurochemistry, 2002, Volume: 81, Issue:5

    Topics: Animals; Behavior, Animal; Cholecystokinin; Chromatography, High Pressure Liquid; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Extracellular Space; Injections, Intraperitoneal; Male; Microdialysis; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Time Factors; Wakefulness

2002
The role of dopamine in motor symptoms in the R6/2 transgenic mouse model of Huntington's disease.
    Journal of neurochemistry, 2002, Volume: 81, Issue:1

    Topics: Aging; Animals; Behavior, Animal; Brain; Brain Chemistry; Central Nervous System Stimulants; Cocaine; Diabetes Complications; Diabetes Mellitus; Disease Models, Animal; Disease Progression; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Female; Glucose Tolerance Test; Huntington Disease; Levodopa; Methamphetamine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Spatial Behavior; Survival Rate

2002
Intravenous cocaine-induced activity in A/J and C57BL/6J mice: behavioral sensitization and conditioned activity.
    Neuropharmacology, 2002, Volume: 42, Issue:7

    Topics: Animals; Cocaine; Conditioning, Psychological; Cues; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Infusions, Intravenous; Infusions, Parenteral; Male; Mice; Mice, Inbred A; Mice, Inbred C57BL; Motor Activity

2002
Adaptation to repeated cocaine administration in rats.
    Annals of the New York Academy of Sciences, 2002, Volume: 965

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Caudate Nucleus; Cocaine; Cocaine-Related Disorders; Cortical Synchronization; Disease Models, Animal; Dopamine; Drug Administration Schedule; Electroencephalography; Frontal Lobe; Homovanillic Acid; Humans; Male; Rats; Rats, Sprague-Dawley

2002
Behavior maintained by termination of a schedule of self-administered cocaine.
    Science (New York, N.Y.), 1979, Jun-15, Volume: 204, Issue:4398

    Topics: Animals; Behavior, Animal; Cocaine; Disease Models, Animal; Haplorhini; Humans; Male; Reinforcement, Psychology; Saimiri; Self Administration; Substance-Related Disorders

1979
Postsynaptic supersensitivity and kindling: further evidence of similarities.
    The American journal of drug and alcohol abuse, 1978, Volume: 5, Issue:2

    Topics: Animals; Apomorphine; Behavior; Cocaine; Dextroamphetamine; Disease Models, Animal; Humans; Injections, Intraperitoneal; Rats; Receptors, Dopamine; Stereotyped Behavior; Time Factors

1978
Behavioral analysis of chronic cocaine intoxication in the cat.
    Biological psychiatry, 1978, Volume: 13, Issue:2

    Topics: Amygdala; Animals; Behavior, Animal; Cats; Cocaine; Disease Models, Animal; Drug Tolerance; Female; Injections, Intravenous; Movement; Posture; Salivation; Seizures; Time Factors; Tremor

1978
Cocaine self-administration in monkeys by chewing and smoking.
    Pharmacology, biochemistry, and behavior, 1976, Volume: 4, Issue:4

    Topics: Animals; Choice Behavior; Coca; Cocaine; Conditioning, Operant; Disease Models, Animal; Haplorhini; Humans; Macaca mulatta; Male; Pharmaceutical Vehicles; Pilot Projects; Plants, Medicinal; Smoking; Substance-Related Disorders; Time Factors

1976
Cocaine psychoses: a continuum model.
    The American journal of psychiatry, 1975, Volume: 132, Issue:3

    Topics: Aggression; Animals; Anxiety; Bipolar Disorder; Blood Pressure; Cocaine; Delusions; Depression; Disease Models, Animal; Disease Susceptibility; Dose-Response Relationship, Drug; Euphoria; Hallucinations; Humans; Psychoses, Substance-Induced; Pulse; Schizophrenia; Stress, Psychological; Substance-Related Disorders

1975
Effect of murine retroviral infection on hair and serum levels of cocaine and morphine.
    Forensic science international, 1992, Volume: 54, Issue:1

    Topics: Age Factors; Animals; Cocaine; Disease Models, Animal; Female; Hair; Injections, Intraperitoneal; Mice; Mice, Inbred C57BL; Morphine; Radioimmunoassay; Retroviridae Infections

1992
Alteration of thymic cell subsets by cocaine administration and murine retrovirus infection in protein undernourished mice.
    Thymus, 1992, Volume: 20, Issue:3

    Topics: Animals; Biomarkers; Cocaine; Disease Models, Animal; Female; Immunocompromised Host; Immunologic Deficiency Syndromes; Leukemia Virus, Murine; Leukocyte Count; Mice; Mice, Inbred C57BL; Murine Acquired Immunodeficiency Syndrome; Organ Size; Protein Deficiency; T-Lymphocyte Subsets; Thymus Gland

1992
Bromocriptine reverses the elevation in intracranial self-stimulation thresholds observed in a rat model of cocaine withdrawal.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1992, Volume: 7, Issue:3

    Topics: Analysis of Variance; Animals; Bromocriptine; Cocaine; Disease Models, Animal; Male; Rats; Rats, Wistar; Regression Analysis; Self Stimulation; Substance Withdrawal Syndrome

1992
Preclinical methods for the development of pharmacotherapies for cocaine abuse.
    NIDA research monograph, 1992, Volume: 119

    Topics: Animals; Cocaine; Disease Models, Animal; Drug Evaluation; Macaca mulatta; Research Design; Self Administration; Substance Abuse, Intravenous

1992
Dopamine fiber detection by [11C]-CFT and PET in a primate model of parkinsonism.
    Neuroreport, 1992, Volume: 3, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Cocaine; Disease Models, Animal; Dopamine; Immunohistochemistry; Macaca fascicularis; Motor Activity; Nerve Fibers; Parkinson Disease, Secondary; Radioligand Assay; Tomography, Emission-Computed

1992
Modulation of tumor necrosis factor and gamma interferon production by cocaine and morphine in aging mice infected with LP-BM5, a murine retrovirus.
    Journal of leukocyte biology, 1991, Volume: 50, Issue:4

    Topics: Aging; Animals; Cocaine; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Interferons; Mice; Mice, Inbred C57BL; Morphine; Murine Acquired Immunodeficiency Syndrome; Retroviridae; Retroviridae Infections; Spleen; Tumor Necrosis Factor-alpha

1991
Effects of prenatal cocaine exposure on perinatal morbidity and postnatal growth in the rabbit.
    Developmental pharmacology and therapeutics, 1991, Volume: 16, Issue:4

    Topics: Abortion, Spontaneous; Animals; Animals, Newborn; Cocaine; Disease Models, Animal; Female; Fetal Death; Fetal Growth Retardation; Fetus; Humans; Infant, Newborn; Pregnancy; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Rabbits

1991
A silicone pellet for continuous cocaine: comparison with continuous amphetamine.
    Pharmacology, biochemistry, and behavior, 1991, Volume: 38, Issue:4

    Topics: Animals; Behavior, Animal; Cocaine; Dextroamphetamine; Disease Models, Animal; Drug Implants; Male; Psychoses, Substance-Induced; Rats; Rats, Inbred Strains; Silicones

1991
Establishment of chronic intravenous drug self-administration in the C57BL/6J mouse.
    Neuroreport, 1991, Volume: 2, Issue:8

    Topics: Animals; Cocaine; Disease Models, Animal; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Morphine; Pentobarbital; Self Administration; Species Specificity; Substance-Related Disorders

1991
Splenocyte subsets in normal and protein malnourished mice after long-term exposure to cocaine or morphine.
    Life sciences, 1991, Volume: 49, Issue:17

    Topics: Animals; Antigens, Surface; Cocaine; Disease Models, Animal; Female; Leukocyte Count; Lymphocyte Subsets; Macrophages; Mice; Mice, Inbred C57BL; Morphine; Nutrition Disorders; Organ Size; Spleen; Substance-Related Disorders

1991
Effects of cocaine on tyrosine hydroxylase activity in brain areas from SHR and WKY.
    Brain research bulletin, 1990, Volume: 25, Issue:4

    Topics: Animals; Brain; Cocaine; Disease Models, Animal; Dopamine; Hypertension; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tyrosine 3-Monooxygenase

1990
Maternal cocaine addiction. II: An animal model for the study of brainstem mechanisms operative in sudden infant death syndrome.
    Medical hypotheses, 1990, Volume: 33, Issue:4

    Topics: Animals; Brain Stem; Cocaine; Disease Models, Animal; Female; Humans; Hypoxia; Infant; Maternal-Fetal Exchange; Neurotransmitter Agents; Pregnancy; Rabbits; Respiratory System; Substance-Related Disorders; Sudden Infant Death

1990
Postcocaine anhedonia. An animal model of cocaine withdrawal.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1991, Volume: 4, Issue:1

    Topics: Analysis of Variance; Animals; Brain; Cocaine; Disease Models, Animal; Male; Rats; Rats, Inbred Strains; Regression Analysis; Self Stimulation; Substance Withdrawal Syndrome

1991
Animal model for investigating the anxiogenic effects of self-administered cocaine.
    Psychopharmacology, 1991, Volume: 103, Issue:4

    Topics: Animals; Anxiety; Behavior, Animal; Cocaine; Conditioning, Operant; Conflict, Psychological; Diazepam; Disease Models, Animal; Male; Rats; Rats, Inbred Strains; Self Administration

1991
Cocaine-base smoking in rhesus monkeys: reinforcing and physiological effects.
    Psychopharmacology, 1990, Volume: 102, Issue:4

    Topics: Animals; Blood Pressure; Cocaine; Disease Models, Animal; Dose-Response Relationship, Drug; Heart Rate; Humans; Lidocaine; Macaca mulatta; Male; Reinforcement, Psychology; Smoking; Substance-Related Disorders

1990
Cocaine-induced liver cell injury: comparison of morphological features in man and in experimental models.
    Hepatology (Baltimore, Md.), 1990, Volume: 11, Issue:4

    Topics: Adult; Animals; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 Enzyme System; Disease Models, Animal; Humans; Liver; Male; Mice; Necrosis; Rhabdomyolysis

1990
The effects of capsaicin treatment on self-administration of amphetamine vapor in rats.
    NIDA research monograph, 1989, Volume: 95

    Topics: Administration, Inhalation; Amphetamine; Animals; Brain; Capsaicin; Cocaine; Disease Models, Animal; Rats; Rats, Inbred Strains; Self Administration; Substance P

1989
The actions of nicotine and cocaine in a mouse model of anxiety.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 33, Issue:1

    Topics: Animals; Anxiety; Behavior, Animal; Cocaine; Discrimination, Psychological; Disease Models, Animal; Light; Male; Mice; Mice, Inbred Strains; Nicotine; Substance Withdrawal Syndrome

1989
Animal models of intravenous phencyclinoid self-administration.
    Pharmacology, biochemistry, and behavior, 1987, Volume: 27, Issue:2

    Topics: Animals; Cocaine; Conditioning, Operant; Disease Models, Animal; Female; Infusions, Intravenous; Ketamine; Phencyclidine; Phencyclidine Abuse; Rats; Reinforcement Schedule; Self Administration; Substance-Related Disorders

1987
Cocaine self-administration in rats influenced by environmental conditions: implications for the etiology of drug abuse.
    Neuroscience letters, 1987, Oct-16, Volume: 81, Issue:1-2

    Topics: Animals; Cocaine; Disease Models, Animal; Rats; Self Administration; Social Environment; Social Isolation; Substance-Related Disorders

1987
Crack cocaine inhalation induces schizophrenia-like symptoms and molecular alterations in mice prefrontal cortex.
    Journal of psychiatric research, 2017, Volume: 91

    Topics: Animals; Crack Cocaine; Disease Models, Animal; Gene Expression Regulation; Interpersonal Relations; Male; Maze Learning; Memory Disorders; Memory, Short-Term; Mice; Mice, Inbred C57BL; Prefrontal Cortex; Protein Isoforms; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Schizophrenic Psychology

2017
Impairment of spatial working memory and oxidative stress induced by repeated crack cocaine inhalation in rats.
    Behavioural brain research, 2019, 02-01, Volume: 359

    Topics: Administration, Inhalation; Advanced Oxidation Protein Products; Animals; Catalase; Crack Cocaine; Disease Models, Animal; Gas Chromatography-Mass Spectrometry; Glutathione Peroxidase; Lipid Peroxidation; Male; Maze Learning; Memory Disorders; Memory, Short-Term; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase

2019
The Effect of Flavored E-cigarettes on Murine Allergic Airways Disease.
    Scientific reports, 2019, 09-20, Volume: 9, Issue:1

    Topics: Airway Remodeling; Animals; Bronchial Hyperreactivity; Bronchitis; Cola; Disease Models, Animal; E-Cigarette Vapor; Female; Flavoring Agents; Glycyrrhiza; Male; Mice; Mice, Inbred BALB C; Nicotine; Pyroglyphidae

2019
[Anti-Candida activity of aroma candy and its protective activity against murine oral candidiasis].
    Medical mycology journal, 2015, Volume: 56, Issue:1

    Topics: Acyclic Monoterpenes; Animals; Candida albicans; Candidiasis, Oral; Candy; Cassia; Catechin; Codonopsis; Decanoic Acids; Disease Models, Animal; Drug Combinations; Drug Resistance, Fungal; Fatty Acids; Glycyrrhiza; Maltose; Mice; Mice, Inbred ICR; Monoterpenes; Phenols; Plant Extracts; Polyphenols; Propolis; Specific Pathogen-Free Organisms; Starch; Sugar Alcohols; Treatment Outcome

2015
Di-D-fructose dianhydride-enriched caramels: effect on colon microbiota, inflammation, and tissue damage in trinitrobenzenesulfonic acid-induced colitic rats.
    Journal of agricultural and food chemistry, 2010, May-26, Volume: 58, Issue:10

    Topics: Animals; Anti-Inflammatory Agents; Candy; Colitis; Colon; Disaccharides; Disease Models, Animal; Female; Food Handling; Food, Fortified; Glycosylation; Hot Temperature; Oligosaccharides; Prebiotics; Rats; Rats, Wistar; Stereoisomerism; Sucrose; Trinitrobenzenesulfonic Acid

2010