cocaine has been researched along with Aging in 232 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 33 (14.22) | 18.7374 |
| 1990's | 63 (27.16) | 18.2507 |
| 2000's | 78 (33.62) | 29.6817 |
| 2010's | 51 (21.98) | 24.3611 |
| 2020's | 7 (3.02) | 2.80 |
| Authors | Studies |
|---|---|
| Baccarelli, AA; Bollati, V; Campisi, M; Carta, A; Hoxha, M; Mastrangelo, G; Mielżyńska-Švach, D; Pavanello, S; Porru, S | 1 |
| Bruneau, J; Høj, SB; Larney, S; Makarenko, I; Minoyan, N; Zolopa, C | 1 |
| Curry, SH; Marler, M | 1 |
| Cann, C; Hope, BT; Ramsey, LA; Venniro, M | 1 |
| Howell, BR; Howell, LL; Katznelson, S; Kochoian, B; McCormack, KM; Morin, EL; Nader, MA; Sanchez, MM; Siebert, ER; Wakeford, AGP | 1 |
| Bis-Humbert, C; García-Cabrerizo, R; García-Fuster, MJ | 1 |
| Ambrosio, E; Capellán, R; Gómez-Rubio, L; Higuera-Matas, A; Orihuel, J; Roura-Martínez, D; Ucha, M; Valverde, C | 1 |
| Lutfy, K; Singh, PK | 1 |
| Andrews, AM; Cannella, LA; Lutton, EM; Merkel, SF; Ramirez, SH; Razmpour, R | 1 |
| Li, Y; Liu, QS; Yu, L; Zeng, F; Zhao, L | 1 |
| Caffino, L; Fumagalli, F; Messa, G | 1 |
| Crawford, CA; Eaton, SE; Katz, CG; McDougall, SA; Mohd-Yusof, A; Ramirez, GI; Real, V; Teran, A | 1 |
| Ford, KA; Marinelli, M; McCutcheon, JE; Pagels, NE; Wong, WC | 1 |
| Hall, FS; Itokawa, K; Lesch, KP; Moessner, R; Schmitt, A; Sora, I; Uhl, GR | 1 |
| Belluzzi, JD; Leslie, FM; Mojica, CY | 1 |
| Baarendse, PJ; Limpens, JH; Vanderschuren, LJ | 1 |
| Aguilar, MA; Daza-Losada, M; Maldonado, C; Miñarro, J; Montagud-Romero, S; Rodríguez-Arias, M; Vidal-Infer, A | 1 |
| Gonzalez, AE; McDougall, SA; Mohd-Yusof, A; Veliz, A | 1 |
| Kabir, ZD; Katzman, A; Kennedy, B; Kosofsky, BE; Lahvis, GP | 1 |
| Bentley, TA; France, CP; Grenier, AE; Serafine, KM | 1 |
| Bradberry, CW; Himes, ML; Jedema, HP; Lopresti, BJ; Mason, NS; Narendran, R | 1 |
| Bryant, S; Dawson, BL; Doyle, HH; Helton, AK; Lloyd, SA; Picou, BN; Ross, JM; Schulz, J; Shanks, RA; Tavares, C | 1 |
| Carroll, ME; Holtz, NA | 1 |
| Baladi, MG; Daws, LC; France, CP; Horton, RE; Owens, WA | 1 |
| Aguilar, MA; Maldonado, C; Manzanedo, C; Miñarro, J; Montagud-Romero, S; Rodríguez-Arias, M | 1 |
| Boivin, JR; Piscopo, DM; Wilbrecht, L | 1 |
| Cryan, JF; Glennon, J; Moloney, RD; O'Connor, RM; Vlachou, S | 1 |
| Nosek, MR; Ossyra, JR; Rhodes, JS; Romanova, EV; Rubakhin, SS; Sweedler, JV; Zombeck, JA | 1 |
| Dwoskin, LP; Jordan, CJ; Kantak, KM; Taylor, DM | 1 |
| Buckner, RL; Hedden, T; Johnson, KA; Rieckmann, A; Sperling, RA; Younger, AP | 1 |
| Corthell, JT; Ferrario, CR; Maust, JD; Oginsky, MF | 1 |
| Alajaji, M; Carroll, FI; Damaj, MI; Kota, D; Lazenka, MF; Levine, A; Selley, DE; Sim-Selley, LJ; Wise, LE; Younis, RM | 1 |
| Izenwasser, S; Reed, SC | 1 |
| Bhide, PG; Cannon, EN; Darnell, SB; Huizenga, MN; McCarthy, DM; Mueller, KA; Sadri-Vakili, G | 1 |
| Álvarez-Dolado, M; Castilla-Ortega, E; Ladrón de Guevara-Miranda, D; Martínez-Losa, M; Millón, C; Missiroli, M; Pavón, FJ; Pérez-Fernández, M; Rodríguez de Fonseca, F; Rosell-Valle, C; Santín, LJ; Serrano, A | 1 |
| Belluzzi, JD; Franke, RM; Leslie, FM; Park, M | 1 |
| Cruz, FC; Marin, MT; Planeta, CS | 1 |
| Brooks, MP; Caster, JM; Kuhn, CM; Schramm-Sapyta, NL; Walker, QD; Waller, ST | 1 |
| Davis, CM; Dominguez, JM; Kohut, SJ; Rice, KC; Riley, AL; Roma, PG; Saria, A; Zernig, G | 1 |
| Ameis, K; Johnston, M; Kuhn, D; Sobrian, SK; Wright, J | 1 |
| Amodeo, DA; Charntikov, S; Cortez, AM; Crawford, CA; Martinez, CE; McDougall, SA | 1 |
| Izenwasser, S; Wade, D; Zakharova, E | 1 |
| Anderson, KL; Balda, MA; Itzhak, Y | 1 |
| Ishibashi, K; Ishii, K; Ishiwata, K; Kawasaki, K; Mizusawa, H; Oda, K | 1 |
| Bowser, M; DeLuca, S; Johnson, HL; Lewis, MW; Phillips, G; Rosen, TS | 1 |
| Dafny, N; King, LN; Swann, AC; Yang, PB | 1 |
| Belluzzi, JD; Dao, JM; Leslie, FM; McQuown, SC | 1 |
| Carson, RE; Ding, YS; Gallezot, JD; Henry, S; Labaree, D; Malison, RT; Nabulsi, N; Neumeister, A; Planeta-Wilson, B; Ropchan, J; Singhal, T; Williams, W | 1 |
| Cuadra, GR; Orsingher, OA; Valdomero, A; Velazquez, EE | 1 |
| Gupta, T; Lewicki, AD; Patel, K; Rhodes, JS; Zombeck, JA | 1 |
| Rosario, A; Santucci, AC | 1 |
| Charntikov, S; Cortez, AM; Crawford, CA; Der-Ghazarian, T; Horn, LR; McDougall, SA | 1 |
| Andersen, SL; Chen, YI; Choi, JK; Jenkins, BG; Ren, J; Xu, H | 1 |
| Ambrosio, E; Del Olmo, N; Desco, M; García-Lecumberri, C; García-Vázquez, V; Higuera-Matas, A; Miguéns, M; Montoya, GL; Pascau, J; Soto-Montenegro, ML; Vaquero, JJ | 1 |
| Blaha, CD; Chesler, EJ; Dickson, PE; Goldowitz, D; Lester, DB; Matta, SG; Miller, MM; Mittleman, G; Rogers, TD | 1 |
| Anker, JJ; Carroll, ME; Navin, SF; Zlebnik, NE | 1 |
| Castellanos, KA; Greenfield, VY; Gutierrez, A; Horn, LR; Kozanian, OO; McDougall, SA; Mohd-Yusof, A | 1 |
| Drescher, C; Foscue, EP; Kuhn, CM; Schramm-Sapyta, NL | 1 |
| Dow-Edwards, D; Izenwasser, S | 1 |
| Carrier, N; Dietz, DM; Gaval-Cruz, M; Hollis, F; Kabbaj, M | 1 |
| Acosta-Torres, S; Blum, JS; Grigson, PS; Puhl, MD | 1 |
| Aumann, M; Baladi, MG; France, CP; Koek, W; Velasco, F | 1 |
| Caffino, L; Calabrese, F; Fumagalli, F; Giannotti, G; Racagni, G | 1 |
| Corley, G; Kovalevich, J; Langford, D; Rawls, SM; Yen, W | 1 |
| Fukumoto, D; Harada, N; Kakiuchi, T; Nishiyama, S; Satoh, K; Tsukada, H | 1 |
| Andersen, ML; Bignotto, M; Machado, RB; Tufik, S | 1 |
| Frys, KA; Middaugh, LD; Price, KL; Szumlinski, KK | 1 |
| Canas, E; Ehrlich, ME; Sommer, J; Unterwald, EM | 1 |
| Froelick, GJ; Kim, DS; Palmiter, RD | 1 |
| Barthel, H; Hesse, S; Kluge, R; Müller, D; Müller, U; Murai, T; Sabri, O; Seese, A | 1 |
| Marr, L; Ressman, K; Sobrian, SK | 1 |
| Ishiwata, K; Kawamura, K; Oda, K | 1 |
| KADLECOVA, V; PELESKA, M | 1 |
| Andersen, SL; Carlezon, WA; Mague, SD | 1 |
| Pratt, AR; Schramm-Sapyta, NL; Winder, DG | 1 |
| Fukui, R; Greengard, P; Higashi, H; Matsuishi, T; Nairn, AC; Nishi, A; Svenningsson, P | 1 |
| Bosson, P; Brådvik, B; Grabowski, M; Lindström, M; Rosén, I; Ryding, E; Träskman-Bendz, L | 1 |
| Andersen, ML; Bignotto, M; Papale, LA; Tufik, S | 1 |
| Cohen, OS; Glatt, SJ; Jackson, D; Simeone, BP; Trksak, GH | 1 |
| Belluzzi, JD; Leslie, FM; Wang, R | 1 |
| Burn, DJ; Colloby, SJ; Fenwick, JD; Firbank, MJ; McKeith, IG; O'Brien, JT; Williams, ED | 1 |
| Backus, W; Baumann, AL; Benveniste, H; Biegon, A; Carter, P; Coplan, JD; Ding, YS; Du, C; Fowler, JS; Gatley, JS; Logan, J; Moller, DH; Rooney, W; Rosenblum, L; Scharf, B; Volkow, ND | 1 |
| Kirstein, CL; Maldonado, AM | 1 |
| Herndon, JG; Killiany, RJ; Luebke, JI; Moore, TL; Moss, MB; Rosene, DL; Schettler, SP | 1 |
| Baldwin, RM; Gelernter, J; Innis, RB; Jacobsen, LK; Laruelle, M; Malison, RT; Seibyl, JP; Staley, JK; van Dyck, CH | 1 |
| Berding, G; Brücke, T; Emrich, HM; Gielow, P; Knapp, WH; Meyer, GJ; Müller-Vahl, KR | 1 |
| Ehrlich, ME; Niculescu, M; Unterwald, EM | 1 |
| Bhat, R; Chari, G; Rao, R | 1 |
| Arguinzoni, JK; Clarke, E; Haddad, GE; Scheer, A; Sobrian, SK | 1 |
| Davis, WI; Francis, D; Harley, J; Kuhar, MJ; Moffett, MC; Sanghani, SP | 1 |
| Chen, ZD; Fang, JJ; Wang, S; Wang, W; Wang, YM; Yang, GS | 1 |
| Chao, L; Laxer, K; Meyerhoff, DJ; Mueller, S; Sacrey, DT; Schuff, N; Weiner, MW | 1 |
| Kuhn, CM; Morris, RW; Schramm-Sapyta, NL | 1 |
| Adler, KJ; Badanich, KA; Kirstein, CL | 1 |
| Levitt, P; Stanwood, GD | 1 |
| Aguilar, MA; Estelles, J; Lluch, J; Miñarro, J; Rodríguez-Arias, M | 1 |
| Belluzzi, JD; Leslie, FM; Lotfipour, S; McQuown, SC; Villégier, AS | 1 |
| Bedi, KS; Ismail, ZI | 1 |
| Cherng, CF; Lin, YC; Su, SW; Yu, L | 1 |
| Lynch, WJ | 1 |
| Dow-Edwards, D; Wang, HY; Zhao, N | 1 |
| Madeira, E; Santucci, AC | 1 |
| Buchwald, WF; Cone, EJ; Darwin, WD; Gorodetzky, CW; Pickworth, WB; Risner, ME; Sharpe, LG | 1 |
| MacDonald, A; McGrath, JC | 1 |
| O'Donnell, SR; Wanstall, JC | 1 |
| Goldberg, PB; Kreider, MS; Roberts, J | 1 |
| Casey, E; Kanel, GC; Shuster, L; Thompson, ML | 1 |
| Alexander, N; Fronek, K | 1 |
| Foldes, A; James, SB | 1 |
| Giacobini, E; Hoffman, DW | 1 |
| Mulvany, MJ; Nyborg, N | 1 |
| Henderson, MG; McMillen, BA | 1 |
| Francis, R; Kuhn, C; Laviola, G; Spear, LP; Wood, RD | 1 |
| Moss, IR; Zhang, C | 1 |
| Factor, EM; Hart, RP; Jonakait, GM | 1 |
| Keller, RW; Snyder-Keller, AM | 1 |
| Baldwin, RM; Charney, DS; Hoffer, PB; Laruelle, M; Malison, RT; Seibyl, JP; van Dyck, CH; Wallace, E; Zea-Ponce, Y; Zoghbi, SS | 1 |
| Atkinson, J; Capdeville-Atkinson, C; Corman, B; Thorin, E | 1 |
| Genova, LM; Hyman, SE; Kosofsky, BE | 1 |
| Carroll, ME; Lac, ST; Specker, SM | 1 |
| Fowler, JS; Hitzemann, R; Logan, J; MacGregor, R; Schlyer, D; Volkow, ND; Wang, GJ; Wolf, AP | 1 |
| Dark, KA; Peeke, HV; Salamy, A; Salfi, M; Shah, SN | 1 |
| Carlson, JN; Glick, SD; Keller, RW; Maisonneuve, IM; Nuccio, DM | 1 |
| Kaufman, MJ; Madras, BK | 1 |
| Seidler, FJ; Slotkin, TA | 1 |
| Arpasi, P; Chakraborty, J | 1 |
| Burge, LJ; Scalzo, FM | 1 |
| Bowman, BP; Kuhn, CM | 1 |
| Babchyck, B; Chaly, T; Dhawan, V; Eidelberg, D; Ishikawa, T; Kazumata, K; Mandel, F; Margouleff, C; Neumeyer, J; Zanzi, I | 1 |
| Bowman, BP; Jones, SR; Kuhn, CM; Wightman, RM | 1 |
| Camp, R; Carroll, M; Pecha, BS; Pecha, RE; Prindiville, T; Trudeau, W | 1 |
| Grilly, DM; Pistell, PJ | 1 |
| Baraban, SC; Schwartzkroin, PA | 1 |
| Bergmans, P; Booij, J; Stoof, JC; Tissingh, G; Van Royen, EA; Winogrodzka, A; Wolters, EC | 2 |
| Abumrad, NN; Fischman, M; Foltin, R; Fowler, JS; Logan, J; Pappas, NR; Volkow, ND; Wang, GJ | 1 |
| Buchholz, J; Hewitt, CW; Sexton, P | 1 |
| Keller, RW; Snyder-Keller, A | 1 |
| Campbell, J; Katovic, N; Silveri, M; Snyder, K; Spear, LP | 1 |
| Lidow, MS | 1 |
| Brown-Woodman, PD; Davies, AN; Sullivan, CE | 1 |
| Busidan, Y; Dow-Edwards, D | 1 |
| Freedland, RL; Gardner, JM; Karmel, BZ; Lewkowicz, DJ | 1 |
| Johns, JM; Lauder, JM; Lubin, DA; Mason, GA; McMillen, BA; Means, LW; Meter, KE; Nelson, CJ; Noonan, LR; Pedersen, CA; Walker, CH; Zimmerman, LI | 1 |
| McReynolds, AM; Meyer, JS | 1 |
| Gillam, MP; Morris, P; Paule, MG | 1 |
| Courtoy, PJ; Evrard, P; Gressens, P; Nassogne, MC | 1 |
| Bolanos, CA; Glatt, SJ; Jackson, D | 1 |
| Kirstein, CL; Philpot, RM | 1 |
| Chen, GJ; Colombo, LL; López, MC; Watson, RR | 1 |
| Angelberger, P; Asenbaum, S; Brücke, T; Hauk, M; Kandlhofer, S; Neumeister, A; Pirker, W; Praschak-Rieder, N; Tauscher, J; Willeit, M | 1 |
| Campbell, JO; Spear, LP; Wood, RD | 1 |
| Friedman, E; Jones, LB; Levitt, P; Reinoso, BS; Stanwood, GD; Wang, HY; Washington, RA | 1 |
| Kehoe, P; Kosten, TA; Miserendino, MJ | 1 |
| Medici, CN; Morin, B; Raap, DK; Smith, RF | 1 |
| de la Torre, R; Gonzalez, ML; Ladona, MG; Peter, RM; Rane, A | 1 |
| Darling, S; Huber, J; Park, K; Soliman, KF | 1 |
| Bohn, MC; Connor, B; Elsworth, JD; Kozlowski, DA; Schallert, T; Tillerson, JL; Unnerstall, JR | 1 |
| Bergström, KA; Karhunen, L; Kuikka, JT; Tammela, L; Tiihonen, J; Uusitupa, M | 1 |
| Hori, M; Kato, B; Kawano, H; Noritake, K; Sakai, K; Shibata, M; Takeuchi, Y; Ueda, S; Wakabayashi, Y; Yasuhara, M; Yoshimoto, K | 1 |
| Stavale, JN; Villares, JC | 1 |
| Elsworth, JD; Morrow, BA; Roth, RH | 2 |
| Berrettini, WH; Dadmarz, M; Ferraro, T; Golden, G; Todte, K; Tselis, N; Vogel, WH | 1 |
| Dadmarz, M; Grathwohl, C; Vogel, WH | 1 |
| Friedman, E; Torres, C; Wang, HY; Zhen, X | 1 |
| Andersen, SL; Arvanitogiannis, A; Carlezon, WA; LeBlanc, C; Pliakas, AM | 1 |
| Matsumoto, AM; Sohn, EH; Wolden-Hanson, T | 1 |
| Boksa, P; El-Khodor, BF | 1 |
| Hickey, MA; Morton, AJ; Reynolds, GP | 1 |
| Castro-Vale, I; de Sousa, L; Magalhães, A; Summavielle, T; Tavares, MA | 1 |
| de Sousa, L; Magalhães, A; Tavares, MA | 1 |
| Alpern, HP; Greer, CA | 1 |
| Baratti, CM; Perec, CJ; Stefano, FJ; Tumilasci, OR | 1 |
| Shuster, L; Webster, GW; Yu, G | 1 |
| Aalkjaer, C; Christensen, J; Mulvany, MJ | 1 |
| Ellinwood, EH; Kilbey, MM | 1 |
| Alhava, E; Attila, M; Rutanen, S | 1 |
| Reith, ME; Selmeci, G | 1 |
| Mortimer, ML; Roberts, J; Tumer, N | 1 |
| Grilly, DM | 1 |
| Alleva, E; Bignami, G; Dell'Omo, G; Laviola, G | 1 |
| Miyashita, Y; Moriya, S; Sugazawa, J; Sugiyama, T; Utsumi, T | 1 |
| Meyer, JS | 1 |
| Carlen, PL; Jahromi, SS; Niesen, C | 1 |
| Henderson, MG; McConnaughey, MM; McMillen, BA | 1 |
| Eikenburg, DC | 1 |
| de Moraes, S; Spadari, RC | 1 |
| Baker, PC; Hoff, KM | 1 |
| Chen, GJ; Watson, RR | 1 |
| Nye, HE; Seidler, FJ; Slotkin, TA | 1 |
| de Avellar, MC; Markus, RP | 1 |
| Anderson-Brown, T; Seidler, FJ; Slotkin, TA | 1 |
| Daniel, KA; Lomax, P | 1 |
| Leibman, D; Smolen, A; Smolen, TN | 1 |
| de Avellar, MC; Kobashi, YL; Markus, RP | 1 |
| Kurth, CD; Roth, RA; Wagerle, LC | 1 |
| Smolen, A; Smolen, TN | 1 |
| Ruiz, B; Wiggins, RC | 2 |
| Ahmad, G; Ali, SF; Bondy, SC; Nakla, M | 1 |
| Daly, RN; Goldberg, PB; Roberts, J | 2 |
| Borton, M; Docherty, JR | 1 |
| Duckles, SP; Handa, RK | 1 |
| Docherty, JR; Hyland, L | 1 |
| Duckles, SP | 1 |
| Goldberg, PB; Kreider, MS; McLean, MR; Roberts, J | 1 |
| Barr, GA; Lithgow, T | 1 |
| Assini, C; Battaini, F; Govoni, S; Missale, C; Pasinetti, G; Spano, PF; Trabucchi, M | 1 |
| Burnstock, G; Furness, JB; McLean, JR | 1 |
| Fujiwara, M; Hattori, K; Mori, J; Sakurai, I; Shibata, S | 1 |
| Ignarro, LJ; Shideman, FE | 1 |
| Gillieron-Christen, M | 1 |
| De Nardi, T; Francke, I; Grassi-Oliveira, R; Kommers-Molina, J; Sanvicente-Vieira, B | 1 |
| Bau, CH; Brietzke, E; de Azeredo, LA; De Nardi, T; Grassi-Oliveira, R; Levandowski, ML; Maurya, PK; Rizzo, LB; Rovaris, DL; Tractenberg, SG; Tyrka, AR | 1 |
| Bueno, HM; Garcia, RC; Hage, M; Hallak, J; Medeiros, MC; Pieri, P; Pires, A; Saldiva, PH; Santos, AB; Yonamine, M; Zorzetto, JC | 1 |
| Bell, DC; Montoya, ID; Richard, AJ | 1 |
| Barch, DM; Luby, JL; Luking, KR | 1 |
| Liem, DG; Mennella, JA | 1 |
| BOURLIERE, F; CENDRON, H; RAPAPORT, A | 1 |
| LUMIA, V | 1 |
| Bandini, LG; Colclough, S; Cyr, H; Dietz, WH; Must, A; Naumova, EN; Phillips, SM | 1 |
| Miettinen, TA; Pitkälä, K; Salomaa, VV; Strandberg, AY; Strandberg, TE; Tilvis, RS | 1 |
| da S Benetti, C; Dalmaz, C; de Oliveira, VS; Diehl, LA; Goldani, MZ; Nunes, E; Portella, AK; Silveira, PP | 1 |
| Burke, V; Devine, A; Dick, IM; Hodgson, JM; Prince, RL | 1 |
| Chen, H; Cupples, LA; Felson, D; Hannan, MT; Kiel, DP; Tucker, KL; Wilson, PW | 1 |
| Kirkova, R; Koleva, M | 1 |
| Macdonald, I | 1 |
| Dunn, RA; Shaw, WD; Trousdale, MA | 1 |
| Davoli, M; Michelozzi, P | 1 |
| Dougherty, SM; Hoffman, MD; Levandoski, SG; Sheldahl, LM; Tristani, FE; Wilke, NA | 1 |
4 review(s) available for cocaine and Aging
| Article | Year |
|---|---|
Ageing and older people who use illicit opioids, cocaine or methamphetamine: a scoping review and literature map.
Topics: Aged; Aging; Analgesics, Opioid; Central Nervous System Stimulants; Cocaine; Humans; Methamphetamine; Quality of Life | 2022 |
Pharmacologic neuroimaging of the ontogeny of dopamine receptor function.
Topics: Adolescent; Adult; Aging; Amphetamine; Animals; Brain; Cerebrovascular Circulation; Cocaine; Dopamine Agonists; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Humans; Magnetic Resonance Imaging; Male; Methylphenidate; Microdialysis; Phenanthridines; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Regional Blood Flow | 2010 |
N-acetylaspartate as a marker of neuronal injury in neurodegenerative disease.
Topics: Aging; Alcoholism; Amyotrophic Lateral Sclerosis; Aspartic Acid; Biomarkers; Brain; Brain Injuries; Choline; Cocaine; Creatine; Epilepsy; Ethanol; HIV Infections; Humans; Magnetic Resonance Imaging; Neurodegenerative Diseases; Neurons; Stress Disorders, Post-Traumatic | 2006 |
Animal behavior models. Increased sensitivity to stressors and other environmental experiences after prenatal cocaine exposure.
Topics: Aging; Animals; Behavior, Animal; Cocaine; Cognition; Environment; Female; Heart Rate; Pregnancy; Prenatal Exposure Delayed Effects; Stress, Psychological | 1998 |
7 trial(s) available for cocaine and Aging
| Article | Year |
|---|---|
Is correction for age necessary in neuroimaging studies of the central serotonin transporter?
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Aging; Brain; Carrier Proteins; Cocaine; Female; Humans; Image Enhancement; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Quality Control; Radiopharmaceuticals; Serotonin Plasma Membrane Transport Proteins; Statistics as Topic; Tissue Distribution; Tomography, Emission-Computed, Single-Photon | 2003 |
A new model for separation between brain dopamine and serotonin transporters in 123I-beta-CIT SPECT measurements: normal values and sex and age dependence.
Topics: Adult; Age Factors; Aged; Aging; Algorithms; Brain; Cocaine; Computer Simulation; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Image Interpretation, Computer-Assisted; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Models, Biological; Nerve Tissue Proteins; Radiopharmaceuticals; Serotonin Plasma Membrane Transport Proteins; Sex Factors; Tissue Distribution; Tomography, Emission-Computed, Single-Photon | 2004 |
The application of statistical parametric mapping to 123I-FP-CIT SPECT in dementia with Lewy bodies, Alzheimer's disease and Parkinson's disease.
Topics: Aged; Aging; Alzheimer Disease; Brain; Brain Mapping; Cocaine; Diagnosis, Differential; Dopamine; Female; Humans; Image Processing, Computer-Assisted; Lewy Body Disease; Male; Neuropsychological Tests; Parkinson Disease; Radiopharmaceuticals; ROC Curve; Tomography, Emission-Computed, Single-Photon | 2004 |
Increased dopamine transporter availability associated with the 9-repeat allele of the SLC6A3 gene.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Female; Gene Frequency; Genetic Testing; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Microsatellite Repeats; Middle Aged; Nerve Tissue Proteins; Polymorphism, Genetic; Radionuclide Imaging; Radiopharmaceuticals; Tissue Distribution | 2005 |
Age-related differences in the chronic and acute response to cocaine in the rat.
Topics: Age Factors; Aging; Animals; Behavior, Animal; Brain; Cocaine; Female; Locomotion; Male; Rats | 1996 |
Heightened sour preferences during childhood.
Topics: Adult; Aging; Candy; Child; Child, Preschool; Discrimination, Psychological; Feeding Behavior; Female; Food Preferences; Humans; Male; Taste; Temperament | 2003 |
Chocolate consumption and bone density in older women.
Topics: Absorptiometry, Photon; Aged; Aged, 80 and over; Aging; Bone Density; Bone Density Conservation Agents; Cacao; Calcium, Dietary; Candy; Cross-Sectional Studies; Dietary Supplements; Female; Humans; Linear Models; Osteoporosis, Postmenopausal; Prospective Studies; Risk Factors; Surveys and Questionnaires | 2008 |
221 other study(ies) available for cocaine and Aging
| Article | Year |
|---|---|
The effect of high polycyclic aromatic hydrocarbon exposure on biological aging indicators.
Topics: Aging; Coke; Environmental Biomarkers; Humans; Male; Occupational Exposure; Polycyclic Aromatic Hydrocarbons; Tumor Suppressor Protein p53 | 2023 |
Effects of ecgonine methyl ester on cognition in scopolamine-impaired and aged rats.
Topics: Aging; Animals; Cholinergic Antagonists; Cocaine; Cognition; Cognition Disorders; Dopamine Uptake Inhibitors; Male; Maze Learning; Memory; Narcotics; Rats; Rats, Sprague-Dawley; Scopolamine | 2020 |
Parametric investigation of social place preference in adolescent mice.
Topics: Aging; Animals; Cocaine; Conditioning, Classical; Female; Male; Mice; Mice, Inbred C57BL; Reward; Sex Characteristics; Social Behavior; Social Isolation | 2020 |
Effects of early life stress on cocaine intake in male and female rhesus macaques.
Topics: Aging; Animals; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Female; Macaca mulatta; Male; Self Administration; Stress, Psychological | 2020 |
Increased negative affect when combining early-life maternal deprivation with adolescent, but not adult, cocaine exposure in male rats: regulation of hippocampal FADD.
Topics: Aging; Animals; Behavior, Animal; Cocaine; Drug-Seeking Behavior; Fas-Associated Death Domain Protein; Hippocampus; Male; Maternal Deprivation; Neuronal Plasticity; Rats; Rats, Sprague-Dawley; Swimming | 2021 |
Cocaine-induced Fos expression in the rat brain: Modulation by prior Δ
Topics: Aging; Animals; Behavior, Animal; Brain Chemistry; Cocaine; Dronabinol; Drug Interactions; Female; Genes, fos; Hallucinogens; Hypothalamus, Posterior; Immunohistochemistry; Male; Motor Cortex; Rats; Rats, Wistar; Sex Characteristics | 2021 |
Nicotine pretreatment reduced cocaine-induced CPP and its reinstatement in a sex- and dose-related manner in adult C57BL/6J mice.
Topics: Aging; Animals; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Extinction, Psychological; Female; Male; Mice; Mice, Inbred C57BL; Nicotine; Nicotinic Agonists; Sex Characteristics | 2017 |
Dexamethasone Attenuates the Enhanced Rewarding Effects of Cocaine Following Experimental Traumatic Brain Injury.
Topics: Aging; Animals; Anti-Inflammatory Agents; Brain Injuries, Traumatic; Cocaine; Dexamethasone; Diagnostic Imaging; Gene Expression Regulation; Immunity; Male; Mice, Inbred C57BL; Monocytes; Neuroglia; Nucleus Accumbens; Phenotype; Reward | 2017 |
Resveratrol modulates cocaine-induced inhibitory synaptic plasticity in VTA dopamine neurons by inhibiting phosphodiesterases (PDEs).
Topics: Aging; Animals; Cocaine; Cocaine-Related Disorders; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dopaminergic Neurons; Endocannabinoids; GABAergic Neurons; gamma-Aminobutyric Acid; Humans; Long-Term Synaptic Depression; Mice; Neuronal Plasticity; Neuroprotective Agents; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Resveratrol; Ventral Tegmental Area | 2017 |
A single cocaine administration alters dendritic spine morphology and impairs glutamate receptor synaptic retention in the medial prefrontal cortex of adolescent rats.
Topics: Adaptor Proteins, Signal Transducing; Aging; Animals; Cocaine; Cytoskeletal Proteins; Dendritic Spines; Disks Large Homolog 4 Protein; Male; Membrane Proteins; Nerve Tissue Proteins; Neuropeptides; Prefrontal Cortex; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2018 |
Age-dependent effects of dopamine receptor inactivation on cocaine-induced behaviors in male rats: Evidence of dorsal striatal D2 receptor supersensitivity.
Topics: Aging; Animals; Behavior, Animal; Cocaine; Corpus Striatum; Dopamine D2 Receptor Antagonists; Locomotion; Male; Quinolines; Rats, Sprague-Dawley; Receptors, Dopamine D2 | 2019 |
Adolescents are more vulnerable to cocaine addiction: behavioral and electrophysiological evidence.
Topics: Action Potentials; Age Factors; Aging; Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Brain; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dopaminergic Neurons; Dose-Response Relationship, Drug; Male; Quinpirole; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Salicylamides; Self Administration; Time Factors; Ventral Tegmental Area | 2013 |
Decreased vesicular monoamine transporter 2 (VMAT2) and dopamine transporter (DAT) function in knockout mice affects aging of dopaminergic systems.
Topics: Aging; Amphetamine; Animals; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Mesencephalon; Mice; Mice, Knockout; Motor Activity; Vesicular Monoamine Transport Proteins | 2014 |
Age-dependent alterations in reward-seeking behavior after brief nicotine exposure.
Topics: Aging; Animals; Appetitive Behavior; Catheters, Indwelling; Cocaine; Conditioning, Operant; Dietary Sucrose; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Extinction, Psychological; Male; Nicotine; Nicotinic Agonists; Rats, Sprague-Dawley; Reward; Self Administration | 2014 |
Disrupted social development enhances the motivation for cocaine in rats.
Topics: Adrenergic alpha-2 Receptor Antagonists; Aging; Animals; Cocaine; Cues; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Extinction, Psychological; Male; Motivation; Rats; Reinforcement Schedule; Self Administration; Social Behavior; Social Isolation; Stress, Psychological; Yohimbine | 2014 |
The novelty-seeking phenotype modulates the long-lasting effects of intermittent ethanol administration during adolescence.
Topics: Adolescent; Aging; Animals; Anxiety; Behavior, Animal; Cocaine; Ethanol; Exploratory Behavior; Humans; Male; Maze Learning; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Phenotype; Reinforcement, Psychology | 2014 |
Role of the D1 receptor for the dopamine agonist-induced one-trial behavioral sensitization of preweanling rats.
Topics: Aging; Animals; Apomorphine; Behavior, Animal; Benzazepines; Central Nervous System Stimulants; Cocaine; Dopamine Agonists; Female; Learning; Male; Methamphetamine; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1 | 2014 |
Effects of prenatal cocaine exposure on social development in mice.
Topics: Aging; Animals; Brain-Derived Neurotrophic Factor; Cocaine; Early Growth Response Protein 1; Female; Gene Expression Regulation; Interpersonal Relations; Male; Mice; Pregnancy; Prenatal Exposure Delayed Effects; Social Behavior; Vocalization, Animal | 2014 |
Eating high fat chow and the behavioral effects of direct-acting and indirect-acting dopamine receptor agonists in female rats.
Topics: Aging; Animals; Body Temperature; Body Weight; Cocaine; Diet, High-Fat; Dietary Fats; Dopamine Agonists; Dopamine D2 Receptor Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Eating; Female; Hypothermia; Indoles; Insulin Resistance; Motor Activity; Piperidines; Quinpirole; Rats, Sprague-Dawley; Receptors, Dopamine D2; Yawning | 2014 |
Decreased vesicular monoamine transporter type 2 availability in the striatum following chronic cocaine self-administration in nonhuman primates.
Topics: Aging; Animals; Brain; Carbon Isotopes; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Dopamine Uptake Inhibitors; Macaca mulatta; Male; Positron-Emission Tomography; Radiopharmaceuticals; Self Administration; Tetrabenazine; Vesicular Monoamine Transport Proteins | 2015 |
Adolescent exposure to cocaine, amphetamine, and methylphenidate cross-sensitizes adults to methamphetamine with drug- and sex-specific effects.
Topics: Aging; Amphetamine; Animals; Central Nervous System Stimulants; Cocaine; Dose-Response Relationship, Drug; Female; Injections, Intraperitoneal; Locomotion; Male; Methamphetamine; Methylphenidate; Mice; Mice, Inbred C57BL; Motor Activity; Sex Factors; Time Factors | 2015 |
Cocaine self-administration punished by intravenous histamine in adolescent and adult rats.
Topics: Administration, Intravenous; Aging; Animals; Animals, Outbred Strains; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Female; Histamine; Histamine Agonists; Models, Animal; Punishment; Rats, Wistar; Self Administration | 2015 |
Eating high fat chow decreases dopamine clearance in adolescent and adult male rats but selectively enhances the locomotor stimulating effects of cocaine in adolescents.
Topics: Aging; Animals; Behavior, Animal; Body Weight; Cocaine; Diet, High-Fat; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Eating; Locomotion; Male; Rats; Rats, Sprague-Dawley; Ventral Striatum | 2015 |
Acute social defeat stress increases the conditioned rewarding effects of cocaine in adult but not in adolescent mice.
Topics: Aggression; Aging; Agonistic Behavior; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Corticosterone; Dose-Response Relationship, Drug; Extinction, Psychological; Male; Mice; Reward; Stress, Psychological | 2015 |
Brief cognitive training interventions in young adulthood promote long-term resilience to drug-seeking behavior.
Topics: Aging; Animals; Cocaine; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Conditioning, Psychological; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Extinction, Psychological; Male; Mice, Inbred C57BL; Motor Activity; Resilience, Psychological; Reward; Spatial Behavior | 2015 |
Enhancing glutamatergic transmission during adolescence reverses early-life stress-induced deficits in the rewarding effects of cocaine in rats.
Topics: Administration, Intravenous; Aging; Amino Acid Transport System X-AG; Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Maternal Deprivation; Memantine; Rats; Receptors, N-Methyl-D-Aspartate; Reward; Riluzole; Self Administration; Stress, Psychological | 2015 |
Differential peptidomics assessment of strain and age differences in mice in response to acute cocaine administration.
Topics: Aging; Animals; Animals, Newborn; Chromatography, Liquid; Cocaine; Dopamine Uptake Inhibitors; Hypothalamic Area, Lateral; Male; Mice; Mice, Inbred Strains; Peptides; Pituitary Gland; Species Specificity; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2015 |
Adolescent D-amphetamine treatment in a rodent model of ADHD: Pro-cognitive effects in adolescence without an impact on cocaine cue reactivity in adulthood.
Topics: Aging; Amphetamine; Animals; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Choice Behavior; Cocaine; Cocaine-Related Disorders; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Male; Psychotropic Drugs; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar; Self Administration | 2016 |
Dopamine transporter availability in clinically normal aging is associated with individual differences in white matter integrity.
Topics: Aged; Aged, 80 and over; Aging; Aniline Compounds; Benzothiazoles; Blood Pressure; Brain; Cocaine; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Magnetic Resonance Imaging; Male; Multimodal Imaging; Organ Size; Positron-Emission Tomography; Radiopharmaceuticals; Regression Analysis; Thiazoles; White Matter | 2016 |
Enhanced cocaine-induced locomotor sensitization and intrinsic excitability of NAc medium spiny neurons in adult but not in adolescent rats susceptible to diet-induced obesity.
Topics: Aging; Animals; Central Nervous System Stimulants; Cocaine; Diet; Dose-Response Relationship, Drug; Glutamates; Male; Motor Activity; Neostriatum; Neurons; Nucleus Accumbens; Obesity; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Synaptic Transmission | 2016 |
Early adolescent nicotine exposure affects later-life cocaine reward in mice.
Topics: Aging; Amphetamine; Animals; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Eating; Male; Mice; Mice, Inbred ICR; Morphine; Narcotics; Nicotine; Nicotinic Agonists; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Reward | 2016 |
Nicotine produces long-term increases in cocaine reinforcement in adolescent but not adult rats.
Topics: Aging; Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug Synergism; Male; Motor Activity; Nicotine; Nicotinic Agonists; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration; Sexual Maturation; Time Factors; Tobacco Use Disorder | 2017 |
Prenatal Cocaine Exposure Alters BDNF-TrkB Signaling in the Embryonic and Adult Brain.
Topics: Aging; Animals; Brain; Brain-Derived Neurotrophic Factor; Cocaine; Female; Mice; Pregnancy; Prenatal Exposure Delayed Effects; Prosencephalon; Protein-Tyrosine Kinases; Receptor, trkB; RNA, Messenger; Signal Transduction | 2016 |
Long-lasting memory deficits in mice withdrawn from cocaine are concomitant with neuroadaptations in hippocampal basal activity, GABAergic interneurons and adult neurogenesis.
Topics: Adaptation, Physiological; Aging; Animals; Behavior, Animal; Cocaine; Cognition Disorders; Dentate Gyrus; Emotions; Exploratory Behavior; gamma-Aminobutyric Acid; Hippocampus; Interneurons; Male; Memory Disorders; Mice, Inbred C57BL; Neurogenesis; Proto-Oncogene Proteins c-fos; Substance Withdrawal Syndrome | 2017 |
Prenatal nicotine exposure changes natural and drug-induced reinforcement in adolescent male rats.
Topics: Aging; Animals; Brain; Brain Chemistry; Causality; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Female; Male; Nicotine; Nicotinic Agonists; Pregnancy; Prenatal Exposure Delayed Effects; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; RNA, Messenger; Self Administration; Smoking; Stereotyped Behavior; Tobacco Use Disorder | 2008 |
Cocaine-induced behavioral sensitization in adolescent rats endures until adulthood: lack of association with GluR1 and NR1 glutamate receptor subunits and tyrosine hydroxylase.
Topics: Aging; Animals; Behavior, Animal; Blotting, Western; Cocaine; Injections, Intraperitoneal; Male; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Tyrosine 3-Monooxygenase | 2008 |
Novelty-induced locomotion is positively associated with cocaine ingestion in adolescent rats; anxiety is correlated in adults.
Topics: Aging; Animals; Anxiety; Cocaine; Cocaine-Related Disorders; Data Interpretation, Statistical; Environment; Female; Male; Motor Activity; Pharmaceutical Solutions; Rats; Reward; Sex Characteristics | 2009 |
The impact of early environmental rearing condition on the discriminative stimulus effects and Fos expression induced by cocaine in adult male and female rats.
Topics: Aging; Animals; Brain; Cocaine; Conditioning, Operant; Discrimination, Psychological; Dopamine Agonists; Female; Genes, fos; Genes, Immediate-Early; Immunohistochemistry; Male; Maternal Deprivation; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Sex Characteristics | 2009 |
Prenatal nicotine and/or cocaine differentially alters nicotine-induced sensitization in aging offspring.
Topics: Adolescent; Adult; Aging; Animals; Behavior, Animal; Child; Cocaine; Dopamine Uptake Inhibitors; Female; Habituation, Psychophysiologic; Humans; Male; Motor Activity; Nicotine; Nicotinic Agonists; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley | 2008 |
Persistence of one-trial cocaine-induced behavioral sensitization in young rats: regional differences in Fos immunoreactivity.
Topics: Aging; Animals; Behavior, Animal; Brain; Central Nervous System Stimulants; Cocaine; Female; Immunohistochemistry; Male; Motor Activity; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley | 2009 |
Sensitivity to cocaine conditioned reward depends on sex and age.
Topics: Aging; Animals; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Female; Male; Rats; Rats, Sprague-Dawley; Reward; Sex Characteristics | 2009 |
Development and persistence of long-lasting behavioral sensitization to cocaine in female mice: role of the nNOS gene.
Topics: Aging; Animals; Cocaine; Dopamine Uptake Inhibitors; Female; Mice; Mice, Knockout; Motor Activity; Nitric Oxide Synthase Type I; Sex Characteristics; Time Factors | 2009 |
Regional analysis of age-related decline in dopamine transporters and dopamine D2-like receptors in human striatum.
Topics: Adult; Age Factors; Aged; Aging; Carbon Isotopes; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Male; Middle Aged; Positron-Emission Tomography; Raclopride; Receptors, Dopamine D2; Young Adult | 2009 |
Cocaine-exposed infant behavior during Still-Face: risk factor analyses.
Topics: Adult; Aging; Caregivers; Cocaine; Facial Expression; Factor Analysis, Statistical; Female; Humans; Infant; Infant Behavior; Infant, Newborn; Male; Maternal-Fetal Exchange; Mother-Child Relations; Pregnancy; Risk Factors; Sex Characteristics | 2009 |
Does a rat's exposure to cocaine during adolescence affect its response to cocaine in adulthood?
Topics: Aging; Analysis of Variance; Animals; Cocaine; Drug Tolerance; Female; Motor Activity; Random Allocation; Rats; Rats, Sprague-Dawley | 2009 |
Age-dependent effects of low-dose nicotine treatment on cocaine-induced behavioral plasticity in rats.
Topics: Adaptation, Physiological; Aging; Analysis of Variance; Animals; Animals, Newborn; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Exploratory Behavior; Locomotion; Male; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley | 2009 |
PET imaging of the effects of age and cocaine on the norepinephrine transporter in the human brain using (S,S)-[(11)C]O-methylreboxetine and HRRT.
Topics: Adult; Aging; Brain; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Female; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Morpholines; Norepinephrine Plasma Membrane Transport Proteins; Positron-Emission Tomography; Radiopharmaceuticals; Reboxetine | 2010 |
Perinatal undernutrition facilitates morphine sensitization and cross-sensitization to cocaine in adult rats: a behavioral and neurochemical study.
Topics: Aging; Animals; Caudate Nucleus; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Female; Locomotion; Male; Malnutrition; Morphine; Narcotics; Nucleus Accumbens; Pregnancy; Prenatal Exposure Delayed Effects; Putamen; Rats; Rats, Wistar | 2010 |
Patterns of neural activity associated with differential acute locomotor stimulation to cocaine and methamphetamine in adolescent versus adult male C57BL/6J mice.
Topics: Aging; Animals; Brain; Caudate Nucleus; Central Nervous System Stimulants; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Immunohistochemistry; Locomotion; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Neurons; Proto-Oncogene Proteins c-fos | 2010 |
Anxiety-like responses in adolescent rats following a 10-11-day withdrawal period from repeated cocaine administration.
Topics: Aging; Analysis of Variance; Animals; Anxiety; Cocaine; Dopamine Uptake Inhibitors; Male; Maze Learning; Neuropsychological Tests; Rats; Rats, Long-Evans; Substance Withdrawal Syndrome; Time Factors | 2010 |
Age-dependent effects of kappa-opioid receptor stimulation on cocaine-induced stereotyped behaviors and dopamine overflow in the caudate-putamen: an in vivo microdialysis study.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Aging; Animals; Animals, Suckling; Caudate Nucleus; Cocaine; Dopamine; Microdialysis; Microinjections; Motor Activity; Putamen; Rats; Receptors, Opioid, kappa; Second Messenger Systems; Stereotyped Behavior | 2010 |
Chronic cannabinoid administration to periadolescent rats modulates the metabolic response to acute cocaine in the adult brain.
Topics: Aging; Animals; Brain; Cannabinoids; Cocaine; Female; Magnetic Resonance Imaging; Male; Neostriatum; Rats; Rats, Wistar; Septal Nuclei | 2011 |
Genotype-dependent effects of adolescent nicotine exposure on dopamine functional dynamics in the nucleus accumbens shell in male and female mice: a potential mechanism underlying the gateway effect of nicotine.
Topics: Aging; Animals; Cocaine; Cocaine-Related Disorders; Dopamine; Female; Genotype; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Nicotine; Nucleus Accumbens; Reward; Sex Characteristics; Species Specificity | 2011 |
Responding during signaled availability and nonavailability of iv cocaine and food in rats: age and sex differences.
Topics: Aging; Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Feeding Behavior; Female; Food; Injections, Intravenous; Male; Rats; Rats, Wistar; Reinforcement Schedule; Self Administration; Sex Characteristics | 2011 |
One-trial behavioral sensitization in preweanling rats: differential effects of cocaine, methamphetamine, methylphenidate, and D-amphetamine.
Topics: Aging; Animals; Animals, Suckling; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Dextroamphetamine; Dose-Response Relationship, Drug; Female; Male; Methamphetamine; Methylphenidate; Motor Activity; Rats; Rats, Sprague-Dawley; Weaning | 2011 |
Individual differences in cocaine conditioned taste aversion are developmentally stable and independent of locomotor effects of cocaine.
Topics: Aging; Animals; Avoidance Learning; Cocaine; Conditioning, Psychological; Individuality; Motor Activity; Rats; Taste | 2011 |
Pretreatment with Δ9-tetrahydrocannabinol (THC) increases cocaine-stimulated activity in adolescent but not adult male rats.
Topics: Aging; Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Dronabinol; Drug Interactions; Dyskinesia, Drug-Induced; Male; Marijuana Smoking; Motor Activity; Psychotropic Drugs; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Time Factors | 2012 |
Juvenile and adult rats differ in cocaine reward and expression of zif268 in the forebrain.
Topics: Aging; Analysis of Variance; Animals; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Early Growth Response Protein 1; Gene Expression Regulation; Locomotion; Male; Prosencephalon; Rats; Rats, Sprague-Dawley; Reward; RNA, Messenger | 2012 |
Environmental enrichment protects against the acquisition of cocaine self-administration in adult male rats, but does not eliminate avoidance of a drug-associated saccharin cue.
Topics: Aging; Animals; Cocaine; Cocaine-Related Disorders; Cues; Environment; Male; Rats; Rats, Sprague-Dawley; Saccharin; Self Administration | 2012 |
Eating high fat chow enhances the locomotor-stimulating effects of cocaine in adolescent and adult female rats.
Topics: Aging; Animals; Cocaine; Corticosterone; Dietary Fats; Dose-Response Relationship, Drug; Estrus; Female; Motor Activity; Rats; Rats, Sprague-Dawley | 2012 |
Dynamic modulation of basic Fibroblast Growth Factor (FGF-2) expression in the rat brain following repeated exposure to cocaine during adolescence.
Topics: Aging; Analysis of Variance; Animals; Brain; Cocaine; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Fibroblast Growth Factor 2; Male; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Stress, Psychological | 2013 |
Cocaine-induced loss of white matter proteins in the adult mouse nucleus accumbens is attenuated by administration of a β-lactam antibiotic during cocaine withdrawal.
Topics: Aging; Animals; beta-Lactams; Caspase 3; Ceftriaxone; Cocaine; Excitatory Amino Acid Transporter 2; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Nucleus Accumbens; Oligodendroglia; Substance Withdrawal Syndrome | 2012 |
Age-related changes in the striatal dopaminergic system in the living brain: a multiparametric PET study in conscious monkeys.
Topics: Aging; Animals; Benzazepines; Cocaine; Corpus Striatum; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Extracellular Space; Levodopa; Macaca mulatta; Magnetic Resonance Imaging; Male; Microdialysis; Piperazines; Raclopride; Tomography, Emission-Computed | 2002 |
Does paradoxical sleep deprivation and cocaine induce penile erection and ejaculation in old rats?
Topics: Aging; Animals; Brain; Cocaine; Ejaculation; Male; Penile Erection; Progesterone; Rats; Rats, Wistar; Receptors, Dopamine; Reflex; Sleep Deprivation; Synaptic Transmission; Testosterone | 2002 |
Unconditioned and conditioned factors contribute to the 'reinstatement' of cocaine place conditioning following extinction in C57BL/6 mice.
Topics: Aging; Animals; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Extinction, Psychological; Male; Mice; Mice, Inbred C57BL; Motor Activity | 2002 |
Periadolescent mice show enhanced DeltaFosB upregulation in response to cocaine and amphetamine.
Topics: Age Factors; Aging; Amphetamine; Amphetamine-Related Disorders; Animals; Caudate Nucleus; Cocaine; Cocaine-Related Disorders; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Plasma Membrane Transport Proteins; Immunoblotting; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Nerve Tissue Proteins; Neuronal Plasticity; Nucleus Accumbens; Phosphoproteins; Proto-Oncogene Proteins c-fos; Putamen; Sexual Maturation; Time; Up-Regulation | 2002 |
Dopamine-dependent desensitization of dopaminergic signaling in the developing mouse striatum.
Topics: Aging; Animals; Aromatic-L-Amino-Acid Decarboxylases; Behavior, Animal; Body Weight; Cocaine; Corpus Striatum; Dopamine; Dopamine Agonists; Immunohistochemistry; Levodopa; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Neurons; Proto-Oncogene Proteins c-fos; Receptors, Dopamine D1; Receptors, Opioid, mu; Signal Transduction; Sodium Chloride | 2002 |
Prenatal cocaine and/or nicotine exposure produces depression and anxiety in aging rats.
Topics: Aging; Animals; Anxiety; Cocaine; Depression; Female; Male; Nicotine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Sex Characteristics | 2003 |
Age-related changes of the [11C]CFT binding to the striatal dopamine transporters in the Fischer 344 rats: a PET study.
Topics: Age Factors; Aging; Animals; Carbon Radioisotopes; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Male; Membrane Glycoproteins; Membrane Transport Proteins; Metabolic Clearance Rate; Nerve Tissue Proteins; Protein Binding; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Inbred F344; Tissue Distribution | 2003 |
[Infrascopic studies. VI. Effect of cocaine on the pupil and its dependence on age as revealed by infrascopic study].
Topics: Aging; Cocaine; Humans; Pupil | 1958 |
Enduring behavioral effects of early exposure to methylphenidate in rats.
Topics: Aging; Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Conditioning, Psychological; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Female; Immobilization; Male; Methylphenidate; Motor Activity; Rats; Rats, Sprague-Dawley; Reaction Time; Swimming; Time Factors | 2003 |
Effects of periadolescent versus adult cocaine exposure on cocaine conditioned place preference and motor sensitization in mice.
Topics: Aging; Analysis of Variance; Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Exploratory Behavior; Male; Mice; Mice, Inbred C57BL; Motor Activity; Reproducibility of Results; Time Factors | 2004 |
Effect of methylphenidate on dopamine/DARPP signalling in adult, but not young, mice.
Topics: Aging; Animals; Animals, Newborn; Benzazepines; Cocaine; Dopamine; Dopamine Agonists; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Antagonists; Dopamine Uptake Inhibitors; Drug Interactions; Immunoblotting; In Vitro Techniques; Male; Methamphetamine; Methylphenidate; Mice; Mice, Inbred C57BL; Neostriatum; Nerve Tissue Proteins; Phosphoproteins; Phosphorylation; Signal Transduction; Threonine | 2003 |
Age-related effects on genital reflexes induced by paradoxical sleep deprivation and cocaine in rats.
Topics: Aging; Animals; Cocaine; Ejaculation; Male; Penile Erection; Rats; Rats, Wistar; Sleep Deprivation; Sleep, REM; Vasoconstrictor Agents | 2004 |
Prenatal cocaine exposure decreases nigrostriatal dopamine release in vitro: effects of age and sex.
Topics: Aging; Animals; Cocaine; Corpus Striatum; Diestrus; Dopamine; Female; Male; Pregnancy; Prenatal Exposure Delayed Effects; Proestrus; Rats; Rats, Long-Evans; Sex Characteristics; Substantia Nigra | 2004 |
Acetaldehyde enhances acquisition of nicotine self-administration in adolescent rats.
Topics: Acetaldehyde; Adolescent; Age Factors; Aging; Animals; Brain; Brain Chemistry; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Synergism; Humans; Male; Nicotiana; Nicotine; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Reinforcement, Psychology; Reward; Self Administration; Tobacco Use Disorder | 2005 |
Maternal and fetal 11C-cocaine uptake and kinetics measured in vivo by combined PET and MRI in pregnant nonhuman primates.
Topics: Aging; Animals; Brain; Carbon Isotopes; Cocaine; Female; Fetus; Image Interpretation, Computer-Assisted; Kinetics; Macaca radiata; Magnetic Resonance Imaging; Maternal-Fetal Exchange; Metabolic Clearance Rate; Organ Specificity; Positron-Emission Tomography; Pregnancy; Pregnancy, Animal; Radiopharmaceuticals; Subtraction Technique; Tissue Distribution | 2005 |
Handling alters cocaine-induced activity in adolescent but not adult male rats.
Topics: Age Factors; Aging; Analysis of Variance; Animals; Behavior, Animal; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Handling, Psychological; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Time Factors | 2005 |
Cognitive impairment in aged rhesus monkeys associated with monoamine receptors in the prefrontal cortex.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Age Factors; Aging; Analysis of Variance; Animals; Autoradiography; Behavior, Animal; Benzazepines; Brain Mapping; Clonidine; Cocaine; Cognition Disorders; Discrimination Learning; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Fluoxetine; Macaca mulatta; Male; Membrane Proteins; Memory; Nerve Tissue Proteins; Neuropsychological Tests; Prazosin; Prefrontal Cortex; Radioligand Assay; Receptors, Catecholamine; Statistics as Topic; Tritium | 2005 |
Serotonin transporter binding in Tourette Syndrome.
Topics: Adult; Aging; Binding, Competitive; Brain; Cocaine; Comorbidity; Female; Humans; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Obsessive-Compulsive Disorder; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Synaptic Transmission; Tomography, Emission-Computed, Single-Photon; Tourette Syndrome | 2005 |
Age-specific behavioral responses to psychostimulants in mice.
Topics: Aging; Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Male; Methylphenidate; Mice; Motor Activity; Stereotyped Behavior | 2005 |
Effects of prenatal cocaine, morphine, or both on postnatal opioid (mu) receptor development.
Topics: Aging; Animals; Brain; Cocaine; Dopamine Antagonists; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Female; Morphine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Sulpiride | 2006 |
Prenatal cocaine alone and combined with nicotine alters ANG II and IGF-1 induced left atrial contractions in aging male offspring.
Topics: Aging; Angiotensin II; Animals; Atrial Function, Left; Cardiotonic Agents; Cocaine; Female; Heart Atria; Insulin-Like Growth Factor I; Male; Myocardial Contraction; Nicotine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley | 2005 |
Maternal separation and handling affects cocaine self-administration in both the treated pups as adults and the dams.
Topics: Aging; Animals; Animals, Newborn; Cocaine; Dose-Response Relationship, Drug; Female; Handling, Psychological; Maternal Behavior; Maternal Deprivation; Motor Activity; Pregnancy; Rats; Rats, Long-Evans; Reinforcement, Psychology; Self Administration | 2006 |
Effect of cocaine on germ cell apoptosis in rats at different ages.
Topics: Aging; Animals; Caspase 3; Caspases; Cell Cycle; Cocaine; Estrogens; Follicle Stimulating Hormone; Luteinizing Hormone; Male; Prolactin; Rats; Rats, Sprague-Dawley; Spermatozoa; Testis; Testosterone | 2006 |
Adolescent rats are protected from the conditioned aversive properties of cocaine and lithium chloride.
Topics: Aging; Animals; Avoidance Learning; Behavior, Animal; Cocaine; Conditioning, Psychological; Lithium Chloride; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Substance-Related Disorders; Taste | 2006 |
Adolescents differ from adults in cocaine conditioned place preference and cocaine-induced dopamine in the nucleus accumbens septi.
Topics: Aging; Animals; Cocaine; Conditioning, Operant; Data Interpretation, Statistical; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Microdialysis; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reward | 2006 |
Prenatal exposure to cocaine produces unique developmental and long-term adaptive changes in dopamine D1 receptor activity and subcellular distribution.
Topics: Adaptation, Physiological; Aging; Animals; Brain; Cocaine; Female; Neuronal Plasticity; Neurons; Pregnancy; Prenatal Exposure Delayed Effects; Rabbits; Receptors, Dopamine D1; Subcellular Fractions; Time Factors; Tissue Distribution | 2007 |
Cocaine exposure during adolescence affects anxiety in adult mice.
Topics: Aging; Animals; Anxiety; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Interpersonal Relations; Male; Mice; Motor Activity | 2007 |
Tranylcypromine enhancement of nicotine self-administration.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Benzazepines; Chromatography, High Pressure Liquid; Cocaine; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Electrochemistry; Half-Life; Male; Microdialysis; Monoamine Oxidase Inhibitors; Nicotine; Nicotinic Agonists; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Reward; Self Administration; Tranylcypromine | 2007 |
Rats exposed to cocaine during late gestation and early postnatal life show deficits in hippocampal pyramidal and granule cells in later life.
Topics: Aging; Animals; Animals, Newborn; Cell Count; Cell Size; Cocaine; Dissection; Dopamine Uptake Inhibitors; Female; Gestational Age; Hippocampus; Neurons; Organ Size; Pregnancy; Prenatal Exposure Delayed Effects; Pyramidal Cells; Rats; Rats, Wistar | 2007 |
Prenatal exposure of bupropion may enhance agitation, anxiety responses, and sensitivity to cocaine effects in adult mice.
Topics: Aging; Animals; Antidepressive Agents, Second-Generation; Anxiety; Bupropion; Cocaine; Dose-Response Relationship, Drug; Female; Mice; Motor Activity; Pregnancy; Prenatal Exposure Delayed Effects; Psychomotor Agitation; Reward | 2007 |
Acquisition and maintenance of cocaine self-administration in adolescent rats: effects of sex and gonadal hormones.
Topics: Aging; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Data Interpretation, Statistical; Estradiol; Estrous Cycle; Female; Gonadal Steroid Hormones; Male; Progesterone; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Self Administration; Sex Characteristics; Testosterone | 2008 |
Cocaine exposure during the early postnatal period diminishes medial frontal cortex Gs coupling to dopamine D1-like receptors in adult rat.
Topics: Aging; Animals; Animals, Newborn; Cell Membrane; Cocaine; Cocaine-Related Disorders; Cognition; Cognition Disorders; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Female; Frontal Lobe; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Male; Memory, Short-Term; Mental Disorders; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, G-Protein-Coupled; Signal Transduction; Synaptic Transmission; Time | 2008 |
Anxiogenesis in adult rats treated chronically with cocaine during adolescence: effects of extended abstinence and 8-OH-DPAT treatment.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Animals; Anxiety Disorders; Brain; Brain Chemistry; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Drug Administration Schedule; Exploratory Behavior; Male; Maze Learning; Motor Activity; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin Receptor Agonists; Substance Withdrawal Syndrome | 2008 |
Progress report from the NIDA Addiction Research Center (preclinical laboratory), Lexington, Kentucky (1984).
Topics: Aging; Animals; Behavior, Animal; beta-Endorphin; Cats; Cocaine; Discrimination Learning; Dogs; Endorphins; Humans; Loperamide; Morphine; National Institutes of Health (U.S.); Norbornanes; Pupil; Rats; Reinforcement, Psychology; Substance-Related Disorders; United States | 1984 |
Post-natal development of functional neurotransmission in rat vas deferens.
Topics: Adrenergic alpha-Agonists; Aging; Animals; Cocaine; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Neuroeffector Junction; Nifedipine; Norepinephrine; Oxymetazoline; Rats; Receptors, Adrenergic, alpha; Synaptic Transmission; Vas Deferens; Xylazine; Yohimbine | 1984 |
Beta-1 and beta-2 adrenoceptor-mediated responses in preparations of pulmonary artery and aorta from young and aged rats.
Topics: Aging; Animals; Aorta; Cocaine; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Isoproterenol; Male; Muscle, Smooth, Vascular; Propranolol; Pulmonary Artery; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1984 |
Effect of age on adrenergic neuronal uptake in rat heart.
Topics: Aging; Analysis of Variance; Animals; Catecholamines; Cocaine; Heart Rate; Isoproterenol; Male; Myocardium; Neurons; Norepinephrine; Rats; Sympathetic Nervous System | 1984 |
Sex and strain differences in response to cocaine.
Topics: Aging; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 Enzyme System; Enzyme Induction; Esterases; Female; Glutathione; Gonadal Steroid Hormones; Male; Mice; Microsomes, Liver; Oxygenases; Sex Factors; Species Specificity | 1984 |
Genetic difference in the sympathetic nervous activity and susceptibility to atherosclerosis in pigeon.
Topics: Aging; Animals; Aorta; Arteriosclerosis; Cocaine; Columbidae; Disease Susceptibility; Muscle Contraction; Norepinephrine; Sympathetic Nervous System | 1981 |
In vitro noradrenaline accumulation by sheep skin: partial characterization and localization.
Topics: Aging; Animals; Cocaine; Dexamethasone; Female; Fetus; In Vitro Techniques; Male; Norepinephrine; Pregnancy; Sheep; Skin; Thyroidectomy | 1981 |
Characteristics of norepinephrine uptake in developing peripheral nerve terminals.
Topics: Aging; Animals; Chick Embryo; Chickens; Cocaine; Desipramine; Iris; Kinetics; Norepinephrine; Ouabain; Sodium; Temperature | 1980 |
An increased calcium sensitivity of mesenteric resistance vessels in young and adult spontaneously hypertensive rats.
Topics: Aging; Animals; Calcium; Cocaine; Hypertension; Mesenteric Arteries; Muscle, Smooth, Vascular; Norepinephrine; Phentolamine; Potassium; Rats; Vascular Resistance | 1980 |
Changes in dopamine, serotonin and their metabolites in discrete brain areas of rat offspring after in utero exposure to cocaine or related drugs.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Amitriptyline; Amygdala; Analysis of Variance; Animals; Brain; Catalepsy; Cocaine; Corpus Striatum; Dopamine; Female; Haloperidol; Hippocampus; Hydroxyindoleacetic Acid; Hypothalamus; Male; Nalidixic Acid; Naphthyridines; Organ Specificity; Prefrontal Cortex; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Reference Values; Serotonin | 1993 |
Cocaine sensitization in periadolescent and adult rats.
Topics: Adrenocorticotropic Hormone; Aging; Animals; Behavior, Animal; Body Weight; Cocaine; Corticosterone; Drinking; Drug Administration Schedule; Drug Tolerance; Eating; Female; Male; Narcotics; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Sex Factors; Testosterone | 1995 |
Age-related mu-, delta-and kappa-opioid ligands in respiratory-related brain regions of piglets: effect of prenatal cocaine.
Topics: Aging; Animals; Animals, Newborn; beta-Endorphin; Brain Stem; Cocaine; Dynorphins; Enkephalin, Methionine; Female; Ligands; Pregnancy; Prenatal Exposure Delayed Effects; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Respiration; Swine | 1995 |
Neurochemical development of the raphe after continuous prenatal cocaine exposure.
Topics: Aging; Animals; Animals, Newborn; Cocaine; Embryonic and Fetal Development; Female; Fetus; Pregnancy; Prenatal Exposure Delayed Effects; Protein Precursors; Raphe Nuclei; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substance P; Tachykinins; Tryptophan Hydroxylase | 1993 |
Prenatal cocaine increases striatal serotonin innervation without altering the patch/matrix organization of intrinsic cell types.
Topics: Acetylcholinesterase; Aging; Animals; Calbindins; Cocaine; Corpus Striatum; Enkephalins; Female; Immunohistochemistry; Male; NADPH Dehydrogenase; Neurons, Afferent; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; S100 Calcium Binding Protein G; Serotonin; Substance P; Substantia Nigra | 1993 |
Age-related decline in striatal dopamine transporter binding with iodine-123-beta-CITSPECT.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Tomography, Emission-Computed, Single-Photon | 1995 |
Sympathetic neurotransmission in the tail artery of aging rats.
Topics: Aging; Anesthesia; Animals; Arteries; Body Weight; Cocaine; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Norepinephrine; Phentolamine; Rats; Rats, Inbred F344; Rats, Wistar; Regional Blood Flow; Sympathetic Nervous System; Synaptic Transmission; Tail; Vasoconstriction | 1994 |
Postnatal age defines specificity of immediate early gene induction by cocaine in developing rat brain.
Topics: Aging; Animals; Autoradiography; Base Sequence; Brain; Cocaine; Dose-Response Relationship, Drug; Female; Gene Expression; Genes, Immediate-Early; Immunohistochemistry; In Situ Hybridization; Molecular Sequence Data; Neostriatum; Pregnancy; Rats; Rats, Sprague-Dawley; Signal Transduction | 1995 |
Food deprivation history and cocaine self-administration: an animal model of binge eating.
Topics: Aging; Animals; Butorphanol; Cocaine; Conditioning, Operant; Disease Models, Animal; Female; Food Deprivation; Hyperphagia; Injections, Intravenous; Rats; Rats, Sprague-Dawley; Self Administration | 1994 |
Decreased dopamine transporters with age in health human subjects.
Topics: Adult; Aging; Basal Ganglia; Biological Transport; Brain; Carrier Proteins; Cerebellum; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Radionuclide Imaging | 1994 |
Cocaine exposure prebreeding to weaning: maternal and offspring effects.
Topics: Aging; Animals; Behavior, Animal; Body Weight; Cocaine; Drinking; Eating; Exploratory Behavior; Female; Lactation; Learning; Male; Maternal Behavior; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Sucking Behavior | 1994 |
Effects of prenatal cocaine exposure on the nigrostriatal dopamine system: an in vivo microdialysis study in the rat.
Topics: Aging; Animals; Animals, Newborn; Brain; Cocaine; Corpus Striatum; Dopamine; Female; Injections; Microdialysis; Osmolar Concentration; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Stress, Physiological; Substantia Nigra | 1994 |
[3H]CFT ([3H]WIN 35,428) accumulation in dopamine regions of monkey brain: comparison of a mature and an aged monkey.
Topics: Aging; Animals; Brain; Cocaine; Corpus Striatum; Injections, Intravenous; Saimiri; Time Factors; Tissue Distribution; Tritium | 1993 |
Prenatal cocaine and cell development in rat brain regions: effects on ornithine decarboxylase and macromolecules.
Topics: Aging; Animals; Body Weight; Brain; Brain Stem; Cocaine; DNA; Drug Administration Schedule; Embryonic and Fetal Development; Female; Fetal Resorption; Gestational Age; Maternal-Fetal Exchange; Mesencephalon; Organ Size; Ornithine Decarboxylase; Pregnancy; Prenatal Exposure Delayed Effects; Prosencephalon; Proteins; Rats; Rats, Sprague-Dawley | 1993 |
Effects of cocaine on fetal and postnatal development in mice.
Topics: Aging; Animals; Body Weight; Cocaine; Embryonic and Fetal Development; Female; Fetus; Gestational Age; Growth; Mice; Mice, Inbred Strains; Pregnancy; Reference Values | 1993 |
Cardiovascular effects of cocaine in infant and juvenile piglets.
Topics: Aging; Animals; Animals, Newborn; Blood Pressure; Cocaine; Female; Heart Rate; Hemodynamics; Injections, Intravenous; Male; Narcotics; Swine | 1995 |
Comparative nigrostriatal dopaminergic imaging with iodine-123-beta CIT-FP/SPECT and fluorine-18-FDOPA/PET.
Topics: Adult; Aged; Aging; Carrier Proteins; Cocaine; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 1996 |
Development of dopamine neurotransmission and uptake inhibition in the caudate nucleus as measured by fast-cyclic voltammetry.
Topics: Aging; Animals; Caudate Nucleus; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Electrochemistry; In Vitro Techniques; Kinetics; Male; Rats; Rats, Sprague-Dawley; Synaptic Transmission | 1996 |
Association of cocaine and methamphetamine use with giant gastroduodenal ulcers.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Anti-Inflammatory Agents, Non-Steroidal; Child; Cocaine; Endoscopy; Female; Humans; Male; Methamphetamine; Middle Aged; Peptic Ulcer; Prognosis | 1996 |
Fluoxetine alters the effects of cocaine on vigilance task performance of rats.
Topics: Aging; Animals; Antidepressive Agents, Second-Generation; Arousal; Cocaine; Discrimination Learning; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Fluoxetine; Logistic Models; Male; Narcotics; Rats; Rats, Inbred F344; Selective Serotonin Reuptake Inhibitors | 1997 |
Effects of prenatal cocaine exposure on the developing hippocampus: intrinsic and synaptic physiology.
Topics: Aging; Animals; Cocaine; Electrophysiology; Extracellular Space; Female; Hippocampus; In Vitro Techniques; Membrane Potentials; Narcotics; Pregnancy; Prenatal Exposure Delayed Effects; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Synapses | 1997 |
Nigrostriatal dopaminergic imaging with iodine-123-beta CIT-FP/SPECT and fluorine-18-FDOPA/PET.
Topics: Aging; Carrier Proteins; Cocaine; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Fluorine Radioisotopes; Humans; Iodine Radioisotopes; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Parkinson Disease; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 1997 |
[123I]beta-CIT single-photon emission tomography in Parkinson's disease reveals a smaller decline in dopamine transporters with age than in controls.
Topics: Adult; Aged; Aging; Brain; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Tomography, Emission-Computed, Single-Photon | 1997 |
Cocaine abusers do not show loss of dopamine transporters with age.
Topics: Adult; Aging; Blood-Brain Barrier; Carrier Proteins; Cerebellum; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Smoking; Substance-Related Disorders | 1997 |
Impact of age on modulation of norepinephrine release from sympathetic nerves in the rat superior mesentery artery.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Adrenergic Fibers; Aging; Animals; Cocaine; Desoxycorticosterone; Electric Stimulation; Idazoxan; Male; Mesenteric Artery, Superior; Norepinephrine; Rats; Rats, Inbred F344; Receptors, Adrenergic, alpha-2; Vasoconstrictor Agents | 1998 |
Stimulant-mediated c-fos induction in striatum as a function of age, sex, and prenatal cocaine exposure.
Topics: Aging; Amphetamine; Animals; Benzazepines; Cocaine; Corpus Striatum; Dopamine Antagonists; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Female; Nerve Tissue Proteins; Pregnancy; Prenatal Exposure Delayed Effects; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Sex Characteristics; Stimulation, Chemical | 1998 |
Nonhuman primate model of the effect of prenatal cocaine exposure on cerebral cortical development.
Topics: Aging; Animals; Cerebral Cortex; Cocaine; Dopamine; Embryonic and Fetal Development; Female; Gene Expression Regulation, Developmental; Humans; Macaca mulatta; Norepinephrine; Pregnancy; Prenatal Exposure Delayed Effects; Receptors, Adrenergic, alpha-2; Receptors, Dopamine D1; Substance-Related Disorders | 1998 |
Neonatal respiratory control in the rat after prenatal cocaine exposure.
Topics: Aging; Animals; Animals, Newborn; Carbon Dioxide; Cocaine; Female; Oxygen; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Respiration | 1998 |
Ontogenic cocaine effects. Evidence for multifactorial mechanisms.
Topics: Aging; Animals; Benzazepines; Brain; Cocaine; Dopamine; Dopamine Agonists; Female; Gestational Age; Glucose; Humans; Limbic System; Male; Motor Activity; Organ Specificity; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Sex Characteristics; Substance-Related Disorders | 1998 |
Prenatal cocaine exposure and stimulus-seeking behaviors during the first year of life.
Topics: Aging; Arousal; Attention; Cocaine; Female; Humans; Infant; Infant, Newborn; Longitudinal Studies; Memory; Pattern Recognition, Visual; Pregnancy; Prenatal Exposure Delayed Effects; Substance-Related Disorders | 1998 |
Chronic cocaine treatment alters social/aggressive behavior in Sprague-Dawley rat dams and in their prenatally exposed offspring.
Topics: Aggression; Aging; Animals; Brain; Cocaine; Female; Gene Expression Regulation, Developmental; Lactation; Oxytocin; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Social Behavior; Substance-Related Disorders | 1998 |
Effects of prenatal cocaine exposure on serotonin and norepinephrine transporter density in the rat brain.
Topics: Aging; Animals; Brain; Carrier Proteins; Cocaine; Female; Fluoxetine; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Organ Specificity; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Reference Values; Serotonin; Serotonin Plasma Membrane Transport Proteins; Symporters | 1998 |
The effects of cocaine on nonhuman primate brain function are age dependent.
Topics: Aging; Animals; Attention; Brain; Cocaine; Color Perception; Discrimination, Psychological; Macaca mulatta; Male; Memory, Short-Term; Motivation; Neuropsychological Tests; Space Perception | 1998 |
In contrast to cocaine, prenatal exposure to methadone does not produce detectable alterations in the developing mouse brain.
Topics: Aging; Animals; Animals, Newborn; Astrocytes; Brain; Cerebral Cortex; Cocaine; Cocaine-Related Disorders; Dendrites; Embryonic and Fetal Development; Female; Heroin Dependence; Humans; Methadone; Mice; Mice, Inbred Strains; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects | 1998 |
Subsensitivity to dopaminergic drugs in periadolescent rats: a behavioral and neurochemical analysis.
Topics: Acetylcholine; Aging; Amphetamine; Animals; Apomorphine; Behavior, Animal; Cocaine; Corpus Striatum; Dopamine Agents; Dopamine Agonists; Dopamine Uptake Inhibitors; Drug Resistance; Grooming; Habituation, Psychophysiologic; In Vitro Techniques; Male; Motor Activity; Nomifensine; Rats; Rats, Long-Evans; Stereotyped Behavior | 1998 |
Repeated cocaine exposure: effects on catecholamines in the nucleus accumbens septi of periadolescent animals.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Catecholamines; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Female; Homovanillic Acid; Male; Microdialysis; Norepinephrine; Nucleus Accumbens; Rats; Rats, Sprague-Dawley | 1999 |
Effect of short-term cocaine administration on the immune system of young and old C57BL/6 female mice.
Topics: Adjuvants, Immunologic; Aging; Animals; B-Lymphocytes; Body Weight; Cell-Free System; Cocaine; Dose-Response Relationship, Immunologic; Drug Administration Schedule; Female; Immune System; Injections, Intraperitoneal; Intestinal Mucosa; Lymphocyte Count; Lymphocyte Subsets; Mice; Mice, Inbred C57BL; Organ Size; Receptors, Interleukin-2; Spleen; T-Lymphocytes; Thy-1 Antigens; Thymus Gland | 1999 |
Imaging serotonin and dopamine transporters with 123I-beta-CIT SPECT: binding kinetics and effects of normal aging.
Topics: Adult; Aging; Brain; Carrier Proteins; Case-Control Studies; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Serotonin; Serotonin Plasma Membrane Transport Proteins; Time Factors; Tomography, Emission-Computed, Single-Photon | 2000 |
Cocaine and morphine-induced place conditioning in adolescent and adult rats.
Topics: Aging; Analgesics, Opioid; Animals; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Female; Male; Morphine; Rats; Rats, Sprague-Dawley; Sex Characteristics | 2000 |
In utero cocaine-induced dysfunction of dopamine D1 receptor signaling and abnormal differentiation of cerebral cortical neurons.
Topics: Aging; Animals; Cerebral Cortex; Cocaine; Dendrites; Embryonic and Fetal Development; Female; GTP-Binding Protein alpha Subunits, Gs; Gyrus Cinguli; Neurons; Pregnancy; Prenatal Exposure Delayed Effects; Pyramidal Cells; Rabbits; Receptors, Dopamine D1; Signal Transduction | 2000 |
Enhanced acquisition of cocaine self-administration in adult rats with neonatal isolation stress experience.
Topics: Aging; Animals; Animals, Newborn; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Corticosterone; Disease Susceptibility; Motor Activity; Rats; Rats, Sprague-Dawley; Self Administration; Social Isolation | 2000 |
Adolescent cocaine and injection stress effects on the estrous cycle.
Topics: Aging; Analysis of Variance; Animals; Body Weight; Cocaine; Cocaine-Related Disorders; Estrus; Female; Injections, Subcutaneous; Ovulation; Periodicity; Rats; Rats, Long-Evans; Sexual Maturation; Stress, Physiological | 2000 |
Cocaine metabolism in human fetal and adult liver microsomes is related to cytochrome P450 3A expression.
Topics: Adolescent; Adult; Aged; Aging; Aryl Hydrocarbon Hydroxylases; Child; Child, Preschool; Chromatography, Gas; Chromatography, High Pressure Liquid; Cocaine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dopamine Uptake Inhibitors; Female; Gas Chromatography-Mass Spectrometry; Humans; In Vitro Techniques; Kinetics; Liver; Microsomes, Liver; Middle Aged; Oxidoreductases, N-Demethylating; Pregnancy | 2000 |
Altered responsiveness to stress and NMDA following prenatal exposure to cocaine.
Topics: Aging; Animals; Behavior, Animal; Cocaine; Cold Temperature; Corticosterone; Dopamine Uptake Inhibitors; Excitatory Amino Acid Agonists; Female; Immobilization; Male; N-Methylaspartate; Pain Measurement; Physical Endurance; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Stress, Psychological; Swimming | 2001 |
Glial cell line-derived neurotrophic factor (GDNF) gene delivery protects dopaminergic terminals from degeneration.
Topics: Aging; Animals; Autoradiography; Carrier Proteins; Cocaine; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Genetic Therapy; Genetic Vectors; Glial Cell Line-Derived Neurotrophic Factor; Male; Membrane Glycoproteins; Membrane Transport Proteins; Microinjections; Motor Activity; Nerve Growth Factors; Nerve Tissue Proteins; Neurons; Neurotransmitter Agents; Oxidopamine; Parkinson Disease, Secondary; Presynaptic Terminals; Rats; Rats, Inbred F344; RNA, Messenger; Substantia Nigra; Tyrosine 3-Monooxygenase | 2001 |
Effects of ageing on serotonin transporters in healthy females.
Topics: Adult; Aged; Aging; Brain; Carrier Proteins; Cerebellum; Cocaine; Female; Humans; Iodine Radioisotopes; Membrane Glycoproteins; Membrane Transport Proteins; Mesencephalon; Middle Aged; Nerve Tissue Proteins; Radiopharmaceuticals; Reference Values; Serotonin; Serotonin Plasma Membrane Transport Proteins; Sex Characteristics; Tomography, Emission-Computed, Single-Photon | 2001 |
Dopamine and serotonin uptake inhibitors on the release of dopamine and serotonin in the nucleus accumbens of young and aged rats.
Topics: Aging; Animals; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Fluoxetine; Male; Neurons; Nucleus Accumbens; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin; Time Factors | 2001 |
Age-related changes in the N-methyl-D-aspartate receptor binding sites within the human basal ganglia.
Topics: Adult; Aged; Aging; Autoradiography; Basal Ganglia; Caudate Nucleus; Cause of Death; Cocaine; Dizocilpine Maleate; Dopamine Uptake Inhibitors; Female; Glutamic Acid; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Nucleus Accumbens; Putamen; Radioligand Assay; Receptors, N-Methyl-D-Aspartate | 2001 |
Prenatal cocaine exposure increases mesoprefrontal dopamine neuron responsivity to mild stress.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Cocaine; Cocaine-Related Disorders; Dopamine; Electric Stimulation; Female; Gyrus Cinguli; Neural Pathways; Neurons; Prefrontal Cortex; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Stress, Physiological; Ventral Tegmental Area | 2001 |
Effects of strain, behavior and age on the self-administration of ethanol, nicotine, cocaine and morphine by two rat strains.
Topics: Administration, Oral; Aging; Animals; Behavior, Animal; Cocaine; Ethanol; Male; Morphine; Nicotine; Rats; Rats, Inbred BN; Rats, Inbred Strains; Rats, Inbred WKY; Self Administration | 2001 |
Oral self-administration of ethanol and cocaine in rats.
Topics: Aging; Alcohol Drinking; Animals; Cocaine; Ethanol; Female; Male; Rats; Rats, Sprague-Dawley; Self Administration; Sex Factors; Substance-Related Disorders | 2001 |
Prenatal exposure to cocaine disrupts D1A dopamine receptor function via selective inhibition of protein phosphatase 1 pathway in rabbit frontal cortex.
Topics: Aging; Animals; Cocaine; Dopamine and cAMP-Regulated Phosphoprotein 32; Enzyme Activation; Female; Frontal Lobe; GTP-Binding Proteins; In Vitro Techniques; Male; Nerve Tissue Proteins; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Pregnancy; Prenatal Exposure Delayed Effects; Protein Binding; Protein Phosphatase 1; Rabbits; Receptors, Dopamine D1; Serine; Signal Transduction | 2001 |
Altered responsiveness to cocaine in rats exposed to methylphenidate during development.
Topics: Adaptation, Physiological; Adult; Aging; Animals; Central Nervous System Stimulants; Child; Cocaine; Conditioning, Classical; Cyclic AMP Response Element-Binding Protein; Humans; Methylphenidate; Nucleus Accumbens; Rats; Receptors, AMPA; Reward; Time Factors | 2002 |
Prenatal cocaine exposure disrupts non-spatial, short-term memory in adolescent and adult male rats.
Topics: Aging; Algorithms; Animals; Cocaine; Dopamine Uptake Inhibitors; Exploratory Behavior; Female; Injections, Intravenous; Male; Memory, Short-Term; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Reinforcement, Psychology | 2002 |
Testosterone (T)-induced changes in arcuate nucleus cocaine-amphetamine-regulated transcript and NPY mRNA are attenuated in old compared to young male brown Norway rats: contribution of T to age-related changes in cocaine-amphetamine-regulated transcript
Topics: Aging; Amphetamine; Animals; Arcuate Nucleus of Hypothalamus; Body Composition; Body Weight; Cocaine; Dopamine Uptake Inhibitors; Hypothalamus; In Situ Hybridization; Male; Nerve Tissue Proteins; Neuropeptide Y; Orchiectomy; Rats; Rats, Inbred BN; RNA, Messenger; Testosterone; Transcription, Genetic | 2002 |
Birth insult and stress interact to alter dopamine transporter binding in rat brain.
Topics: Aging; Animals; Brain; Cesarean Section; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Fetal Hypoxia; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Reference Values; Stress, Physiological | 2002 |
The role of dopamine in motor symptoms in the R6/2 transgenic mouse model of Huntington's disease.
Topics: Aging; Animals; Behavior, Animal; Brain; Brain Chemistry; Central Nervous System Stimulants; Cocaine; Diabetes Complications; Diabetes Mellitus; Disease Models, Animal; Disease Progression; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Female; Glucose Tolerance Test; Huntington Disease; Levodopa; Methamphetamine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Spatial Behavior; Survival Rate | 2002 |
Neonatal exposure to cocaine: altered dopamine levels in the amygdala and behavioral outcomes in the developing rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Amygdala; Animals; Animals, Newborn; Cocaine; Dopamine; Female; Male; Motor Activity; Rats; Rats, Wistar | 2002 |
Postnatal cocaine exposure: effects on behavior of rats in forced swim test.
Topics: Aging; Animals; Cocaine; Female; Male; Motor Activity; Pregnancy; Rats; Rats, Wistar; Swimming | 2002 |
Maturational changes related to dopamine in the effects of d-amphetamine, cocaine, nicotine, and strychnine on seizure susceptibility.
Topics: Aging; Animals; Cocaine; Dextroamphetamine; Dopamine; Mice; Myoclonus; Nicotine; Seizures; Strychnine | 1979 |
Effects of 6-hydroxydopamine Treatment at birth on the submaxillary gland of the rat.
Topics: Aging; Animals; Animals, Newborn; Autonomic Fibers, Postganglionic; Choline O-Acetyltransferase; Cocaine; Electron Transport Complex IV; Female; Fumarate Hydratase; Hydroxydopamines; Isoproterenol; Norepinephrine; Organ Size; Oxygen Consumption; Rats; Salivation; Submandibular Gland; Succinate Dehydrogenase; Sympathectomy; Sympathetic Nervous System | 1975 |
Increased running response to morphine in morphine-pretreated mice.
Topics: Aging; Analgesics, Opioid; Animals; Animals, Newborn; Cocaine; Dextroamphetamine; Dose-Response Relationship, Drug; Drug Tolerance; Female; Hot Temperature; Levorphanol; Male; Mice; Mice, Inbred A; Mice, Inbred C57BL; Morphine; Motor Activity; Naloxone; Reaction Time; Species Specificity; Stereoisomerism; Stimulation, Chemical; Time Factors | 1975 |
Effect of age on noradrenaline sensitivity of mesenteric resistance vessels in spontaneously hypertensive and Wistar-Kyoto rats.
Topics: Aging; Animals; Blood Pressure; Cocaine; Hypertension; Mesenteric Arteries; Norepinephrine; Rats; Species Specificity; Vascular Resistance | 1979 |
The effect of age-related factors on behavior induced by cocaine.
Topics: Aging; Animals; Behavior; Body Weight; Cocaine; Female; Humans; Motor Activity; Rats; Stereotyped Behavior; Time Factors | 1977 |
Toxicity and temperature responses induced by d-amphetamine and cocaine in developing mice.
Topics: Aging; Amphetamine; Animals; Body Temperature; Cocaine; Drug Interactions; Mice | 1976 |
Cocaine binding sites in mouse striatum, dopamine autoreceptors, and cocaine-induced locomotion.
Topics: Aging; Animals; Apomorphine; Cocaine; Corpus Striatum; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Motor Activity; Receptors, Dopamine; Receptors, Opioid | 1992 |
Gender differences in the effect of age on adrenergic neurotransmission in the heart.
Topics: Aging; Animals; Cocaine; Electric Stimulation; Female; Heart Conduction System; Male; Norepinephrine; Rats; Rats, Inbred F344; Sex Characteristics; Sympathetic Nervous System; Synaptic Transmission; Yohimbine | 1992 |
Aging changes the effects of cocaine on vigilance task performance of rats.
Topics: Aging; Animals; Arousal; Attention; Choice Behavior; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Food; Male; Rats; Rats, Inbred Strains; Reaction Time | 1992 |
Ontogeny of cocaine hyperactivity and conditioned place preference in mice.
Topics: Aging; Animals; Cocaine; Conditioning, Operant; Female; Habituation, Psychophysiologic; Male; Mice; Motor Activity; Reinforcement Schedule | 1992 |
[Age effects of topical tyramine and cocaine on the pupil].
Topics: Adolescent; Adult; Aged; Aging; Child; Cocaine; Horner Syndrome; Humans; Middle Aged; Mydriatics; Ophthalmic Solutions; Pupil; Reference Values; Reflex, Pupillary; Tyramine | 1992 |
Prenatal neurochemistry of cocaine.
Topics: Aging; Animals; Brain; Carrier Proteins; Cocaine; Dopamine; Fetus; Gestational Age; Intracellular Membranes; Kinetics; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Drug; Synaptosomes | 1992 |
Amphetamine actions on pre- and postpubertal rat hippocampal dentate granule neurons.
Topics: Aging; Animals; Atenolol; Calcium Channels; Cocaine; Dextroamphetamine; Evoked Potentials; Haloperidol; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Neurons; Propranolol; Rats; Rats, Inbred Strains; Reserpine; Sexual Maturation; Synapses | 1991 |
Long-term consequences of prenatal exposure to cocaine or related drugs: effects on rat brain monoaminergic receptors.
Topics: Aging; Amitriptyline; Animals; Brain; Cerebral Cortex; Cocaine; Corpus Striatum; Female; Male; Nalidixic Acid; Naphthyridines; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Serotonin; Reference Values; Sodium-Potassium-Exchanging ATPase | 1991 |
Age-related changes in vascular sympathetic neurotransmission in the rat kidney.
Topics: Adrenergic alpha-Antagonists; Aging; Animals; Cocaine; Corticosterone; Electric Stimulation; Kidney; Male; Norepinephrine; Rats; Rats, Inbred F344; Vascular Resistance | 1991 |
Subsensitivity to beta-adrenoceptor agonists in pacemakers isolated from senescent rats.
Topics: Adrenergic beta-Agonists; Aging; Animals; Cocaine; Ethanolamines; Heart; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Metoprolol; Norepinephrine; Oxidopamine; Phenoxybenzamine; Rats; Rats, Inbred Strains | 1991 |
The effects of cocaine upon 5-hydroxyindole levels of the maturing mouse brain.
Topics: Aging; Animals; Brain Chemistry; Brain Stem; Cocaine; Hydroxyindoleacetic Acid; Male; Mice; Mice, Inbred Strains; Serotonin | 1991 |
Modulation of tumor necrosis factor and gamma interferon production by cocaine and morphine in aging mice infected with LP-BM5, a murine retrovirus.
Topics: Aging; Animals; Cocaine; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Interferons; Mice; Mice, Inbred C57BL; Morphine; Murine Acquired Immunodeficiency Syndrome; Retroviridae; Retroviridae Infections; Spleen; Tumor Necrosis Factor-alpha | 1991 |
Developmental shift from local to central control of norepinephrine release in the cardiac-sympathetic axis: effects of cocaine and related drugs.
Topics: Abnormalities, Drug-Induced; Aging; Animals; Cocaine; Female; Heart; Lidocaine; Myocardium; Nerve Endings; Norepinephrine; Pregnancy; Rats; Rats, Inbred Strains; Sympathetic Nervous System; Synapses; Yohimbine | 1991 |
Neuronal uptake of noradrenaline in the rat isolated trachea: effect of ageing.
Topics: Aging; Animals; Cocaine; Drug Resistance; In Vitro Techniques; Kinetics; Male; Neurons; Norepinephrine; Rats; Rats, Inbred Strains; Reserpine; Trachea; Tritium | 1990 |
Cocaine acutely inhibits DNA synthesis in developing rat brain regions: evidence for direct actions.
Topics: Aging; Animals; Brain; Cell Division; Cocaine; DNA; Female; Leucine; Lidocaine; Methoxamine; Nerve Tissue Proteins; Phenoxybenzamine; Pregnancy; Rats; Rats, Inbred Strains; Thymidine | 1990 |
Cocaine and body temperature in the rat: effects of exercise and age.
Topics: Aging; Animals; Body Temperature; Cocaine; Female; Physical Conditioning, Animal; Rats; Rats, Inbred Strains; Temperature | 1990 |
Strain, sex and developmental profiles of cocaine metabolizing enzymes in mice.
Topics: Aging; Animals; Cholinesterases; Cocaine; Female; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Microsomes, Liver; Oxidoreductases, N-Demethylating; Oxygenases; Sex Characteristics; Species Specificity | 1990 |
Age-related changes in neuronal uptake of noradrenaline.
Topics: Aging; Animals; Body Weight; Cocaine; Kinetics; Male; Nerve Tissue Proteins; Neurons; Norepinephrine; Organ Size; Rats; Rats, Inbred Strains; Vas Deferens | 1990 |
Sympathetic reactivity of cerebral arteries in developing fetal lamb and adult sheep.
Topics: Aging; Animals; Animals, Newborn; Arterioles; Cerebral Arteries; Cocaine; Electric Stimulation; Fetus; Norepinephrine; Pia Mater; Prazosin; Sheep; Sympathetic Nervous System | 1990 |
Developmental expression of cocaine hepatotoxicity in the mouse.
Topics: Aging; Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Cocaine; Female; Male; Mice; Mice, Inbred Strains; Sex Factors; Species Specificity; Time Factors | 1990 |
Development under the influence of cocaine. II. Comparison of the effects of maternal cocaine and associated undernutrition on brain myelin development in the offspring.
Topics: Aging; Animals; Body Weight; Brain; Cocaine; Female; Maternal-Fetal Exchange; Myelin Sheath; Nutrition Disorders; Organ Size; Pregnancy; Pregnancy Complications; Rats; Reference Values | 1990 |
Development under the influence of cocaine. I. A comparison of the effects of daily cocaine treatment and resultant undernutrition on pregnancy and early growth in a large population of rats.
Topics: Aging; Animals; Body Weight; Brain; Cocaine; Female; Fetal Death; Lactation; Maternal-Fetal Exchange; Nutrition Disorders; Organ Size; Pregnancy; Pregnancy Complications; Rats; Weight Gain | 1990 |
Cerebral ornithine decarboxylase levels following gestational exposure to cocaine.
Topics: Aging; Animals; Brain; Cocaine; Female; Gestational Age; Maternal-Fetal Exchange; Ornithine Decarboxylase; Pregnancy; Rats; Rats, Inbred Strains; Reference Values | 1990 |
The effect of age on presynaptic alpha 2 adrenoceptor autoregulation of norepinephrine release.
Topics: Aging; Animals; Atropine; Cocaine; Heart; Homeostasis; In Vitro Techniques; Male; Metanephrine; Norepinephrine; Rats; Rats, Inbred F344; Receptors, Adrenergic, alpha; Yohimbine | 1989 |
The effects of ageing on neuronal uptake of noradrenaline in the rat.
Topics: Aging; Animals; Cocaine; Corticosterone; Decerebrate State; Heart; Heart Rate; Hemodynamics; Isoproterenol; Male; Neurons; Norepinephrine; Propranolol; Rats; Rats, Inbred Strains | 1989 |
Effects of age on neurotransmission at the cardiac sympathetic neuroeffector junction.
Topics: Aging; Animals; Cocaine; Electric Stimulation; Heart; Male; Neuroeffector Junction; Norepinephrine; Rats; Rats, Inbred F344; Sympathetic Nervous System; Synaptic Transmission | 1988 |
Age-related changes in adrenergic vasoconstrictor responses of the rat hindlimb.
Topics: Adrenergic alpha-Agonists; Adrenergic Fibers; Aging; Animals; Cocaine; Electric Stimulation; Extremities; Male; Methoxamine; Norepinephrine; Phenylephrine; Rats; Rats, Inbred F344; Vasoconstriction | 1987 |
Alpha-adrenoceptor responsiveness in the aged rat.
Topics: Aging; Anesthesia; Animals; Blood Pressure; Cocaine; Decerebrate State; Ethanolamines; Heart Rate; Male; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Xylazine | 1986 |
Effect of norepinephrine uptake blockade on contractile responses to adrenergic nerve stimulation of isolated rat blood vessels: influence of age.
Topics: Aging; Animals; Cocaine; Electric Stimulation; In Vitro Techniques; Norepinephrine; Rats; Rats, Inbred F344; Sympathetic Nervous System; Vasoconstriction | 1987 |
Effects of aging at the adrenergic cardiac neuroeffector junction.
Topics: Aging; Animals; Axons; Cocaine; Heart; Nerve Degeneration; Neuroeffector Junction; Norepinephrine; Rats; Rats, Inbred F344; Receptors, Adrenergic | 1986 |
Pharmaco-ontogeny of reward: enhancement of self-stimulation by D-amphetamine and cocaine in 3- and 10-day-old rats.
Topics: Aging; Amphetamine; Animals; Animals, Newborn; Brain; Cocaine; Electric Stimulation; Female; Male; Rats; Rats, Inbred Strains; Reaction Time; Reward; Self Stimulation | 1986 |
Age-dependent changes in the mechanisms regulating dopamine uptake in the central nervous system.
Topics: Aging; Animals; Brain; Cerebral Cortex; Cocaine; Corpus Striatum; Dopamine; Male; Rats; Rats, Inbred Strains; Sodium Chloride | 1986 |
Distribution of adrenergic nerves and changes in neuromuscular transmission in the mouse vas deferens during postnatal development.
Topics: Aging; Animals; Cocaine; Electrophysiology; Histocytochemistry; Male; Membrane Potentials; Mice; Microscopy, Fluorescence; Neuromuscular Junction; Norepinephrine; Sympathetic Nervous System; Synaptic Transmission; Time Factors; Vas Deferens | 1970 |
Adrenergic innervation and cocaine-induced potentiation of adrenergic responses of aortic strips from young and old rabbits.
Topics: Aging; Animals; Aorta, Thoracic; Calcium; Cobalt; Cocaine; Cold Temperature; Drug Synergism; Histocytochemistry; Male; Manganese; Microscopy, Fluorescence; Muscle Contraction; Muscle, Smooth; Nicotine; Norepinephrine; Phenylephrine; Pyrogallol; Rabbits; Receptors, Adrenergic; Reserpine; Tyramine | 1971 |
Norepinephrine and epinephrine in the embryo and embryonic heart of the chick: uptake and subcellular distribution.
Topics: Aging; Animals; Chick Embryo; Cocaine; Cold Temperature; Egg Yolk; Epinephrine; Female; Microsomes; Myocardium; Norepinephrine; Reserpine; Sympathetic Nervous System; Tritium | 1968 |
[Catamnestic study on the influence of age in former drug addicts (Catamnesis of 37 patients over the age 65)].
Topics: Aged; Aging; Alcoholism; Analgesics; Antitussive Agents; Barbiturates; Chronic Disease; Cocaine; Female; Humans; Hypnotics and Sedatives; Male; Medical History Taking; Morphine Dependence; Prognosis; Scopolamine; Social Adjustment; Substance-Related Disorders; Time Factors | 1968 |
Crack-cocaine dependence and aging: effects on working memory.
Topics: Adolescent; Adult; Aged; Aging; Case-Control Studies; Cocaine-Related Disorders; Crack Cocaine; Female; Humans; Memory, Short-Term; Neuropsychological Tests; Young Adult | 2016 |
Crack cocaine addiction, early life stress and accelerated cellular aging among women.
Topics: Adult; Adult Survivors of Child Abuse; Aging; Analysis of Variance; Cocaine-Related Disorders; Crack Cocaine; Female; Humans; Psychiatric Status Rating Scales; Stress, Psychological; Surveys and Questionnaires; Telomere; Telomere Shortening; Young Adult | 2016 |
Repeated inhalation of crack-cocaine affects spermatogenesis in young and adult mice.
Topics: Administration, Inhalation; Aging; Animals; Apoptosis; Crack Cocaine; Male; Mice; Mice, Inbred BALB C; Smoke; Spermatogenesis; Testis | 2012 |
Age and HIV risk in a national sample of injection drug and crack cocaine users.
Topics: Adolescent; Adult; Age Factors; Aging; Cocaine-Related Disorders; Crack Cocaine; Female; HIV Seropositivity; Humans; Male; Middle Aged; Prevalence; Risk Factors; Risk-Taking; Sexual Behavior; Social Support; Substance Abuse, Intravenous; United States | 2000 |
Kids, candy, brain and behavior: age differences in responses to candy gains and losses.
Topics: Adult; Age Factors; Aging; Analysis of Variance; Brain; Brain Mapping; Candy; Cerebral Cortex; Child; Child Behavior; Feedback, Psychological; Female; Games, Experimental; Humans; Magnetic Resonance Imaging; Male; Motivation; Neostriatum; Reaction Time; Reward; Surveys and Questionnaires; Young Adult | 2014 |
[Modification with age of the thresholds of perception and recognition for salty and sweet tastes in man].
Topics: Aging; Candy; Humans; Male; Perception; Taste | 1958 |
[Research on differential gustatory sensitivity to sweet in persons of different ages].
Topics: Aging; Candy; Humans; Research; Taste | 1961 |
Energy-dense snack food intake in adolescence: longitudinal relationship to weight and fatness.
Topics: Adipose Tissue; Adolescent; Aging; Body Composition; Body Mass Index; Body Weight; Candy; Carbonated Beverages; Child; Diet; Energy Intake; Exercise; Female; Food; Humans; Ice Cream; Longitudinal Studies; Obesity; Television | 2004 |
Chocolate, well-being and health among elderly men.
Topics: Aged; Aged, 80 and over; Aging; Cacao; Candy; Cohort Studies; Depression; Finland; Health Status; Humans; Male; Quality of Life; Socioeconomic Factors; Surveys and Questionnaires | 2008 |
Could preference for palatable foods in neonatally handled rats alter metabolic patterns in adult life?
Topics: Abdominal Fat; Adrenal Glands; Aging; Animals; Animals, Newborn; Behavior, Animal; Blood Glucose; Body Weight; Cacao; Candy; Corticosterone; Eating; Energy Intake; Energy Metabolism; Feeding Behavior; Female; Food Preferences; Habituation, Psychophysiologic; Handling, Psychological; Humans; Insulin; Lipids; Male; Organ Size; Rats; Rats, Wistar; Sex Factors; Time Factors | 2007 |
Bone mineral density and dietary patterns in older adults: the Framingham Osteoporosis Study.
Topics: Aged; Aged, 80 and over; Aging; Alcoholic Beverages; Animals; Bone Density; Bread; Candy; Cohort Studies; Dairy Products; Diet; Dietary Carbohydrates; Edible Grain; Female; Fruit; Humans; Longitudinal Studies; Male; Massachusetts; Meat; Middle Aged; Osteoporosis; Vegetables | 2002 |
[Subjective assessment of stress and monotony in manufacturing workers in the food and flavorings industries].
Topics: Adult; Aging; Boredom; Bulgaria; Candy; Emotions; Female; Food Technology; Humans; Middle Aged; Stress, Psychological; Women, Working | 1988 |
Nutritional consequences of affluence.
Topics: Aging; Arteriosclerosis; Candy; Coronary Disease; Diet; Feeding Behavior; Humans; Legislation, Drug; Life Expectancy; Nutrition Disorders; Obesity; Socioeconomic Factors | 1972 |
The effect of weather on walking behavior in older adults.
Topics: Age Factors; Aged; Aged, 80 and over; Aging; Confidence Intervals; Female; Health Behavior; Humans; Longitudinal Studies; Male; Rain; Self Report; Snow; Surveys and Questionnaires; Temperature; Time Factors | 2012 |
Invest now in adaptive strategies to cope with weather instability.
Topics: Adaptation, Psychological; Aging; Climate Change; Cold Temperature; Environmental Monitoring; Humans; Italy; Mortality; Patient Education as Topic; Seasons; Snow | 2012 |
Effect of age and coronary artery disease on response to snow shoveling.
Topics: Adult; Aging; Coronary Disease; Energy Metabolism; Exercise Test; Hemodynamics; Humans; Male; Middle Aged; Myocardial Infarction; Physical Endurance; Physical Exertion; Snow; Ventricular Function, Left | 1992 |