cocaine and Acute Liver Injury, Drug-Induced

cocaine has been researched along with Acute Liver Injury, Drug-Induced in 76 studies

Research

Studies (76)

Timeframe	Studies, this research(%)	All Research%
pre-1990	22 (28.95)	18.7374
1990's	28 (36.84)	18.2507
2000's	13 (17.11)	29.6817
2010's	10 (13.16)	24.3611
2020's	3 (3.95)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chen, JR; Christiani, DC; Ho, CK; Mao, IF; Wu, MT; Wypij, D	1
Dwornicki, M; Pokrzywnicki, W; Sroczyński, J; Wieja, A	1
Houszka, M; Madej, JA; Peryt, A	1
Daniel, WA; Jastrzębska, J	1
Patel, KH; Stacey, SK; Thomas, KC	1
Bouquet, E; Fauconneau, B; Frouin, E; Lesbordes, M; Pain, S; Pérault-Pochat, MC; Silvain, C	1
Chung, YH; Jang, CG; Jeong, JH; Jung, TW; Kim, DJ; Kim, HC; Lee, SH; Lei, XG; Mai, HN; Nah, SY; Sharma, G; Sharma, N; Shin, EJ	1
Jang, CG; Jeong, JH; Kim, DJ; Kim, HC; Lee, SH; Mai, HN; Nah, SY; Pham, DT; Sharma, G; Sharma, N; Shin, EJ; Trinh, QD	1
Jang, CG; Jeong, JH; Kim, DJ; Kim, HC; Mai, HN; Nah, SY; Pham, DT; Sharma, G; Sharma, N; Shin, EJ; Trinh, QD	1
Barotto, AM; Guollo, F; Narciso-Schiavon, JL; Schiavon, LL; Zannin, M	1
Carlson, M; Duysen, EG; Hinrichs, SH; Li, B; Li, YF; Lockridge, O; Wieseler, S	1
Ashino, T; Iwakura, Y; Kenmotsu, S; Naito-Yamamoto, Y; Numazawa, S; Shioda, S; Sugiuchi, J; Uehara, J; Yoshida, T	1
Jia, FL; Liu, X; Ruan, M; Wu, XY; Xue, R; Zhang, BX	1
Vitcheva, V	1
Chen, C; Gosnell, BA; Shi, X; Yao, D	1
Brimijoin, S; Gao, Y; Geng, L; Kinsey, B; Kosten, TR; Orson, F; Shen, X	1
Abdel-Rahman, MS; Labib, R; Turkall, R	1
Campos Franco, J; González Quintela, A; Martínez Rey, C; Pérez Becerra, E	1
Abdel-Rahman, MS; Turkall, R; Visalli, T	1
Balaguer, F; Fernández, J; Lozano, M; Mas, A; Miquel, R	1
Abd El-Rahman, AM; Ammar, H	1
Cai, QY; Cai, SQ; Chen, HB; Jia, FL; Ou, T; Ruan, M; Zhang, BX; Zhao, ZZ	1
Jiménez Pérez, M; Marín García, D; Olmedo García, R; Santaella Leiva, I	1
Kloss, MW; Rauckman, EJ; Rosen, GM	2
Shuster, L	1
Freeman, RW; Harbison, RD; Teaf, CM	1
Griffeth, LK; Kloss, MW; Rauckman, EJ; Rosen, GM	1
Casey, E; Kanel, GC; Shuster, L; Thompson, ML	1
Evans, MA	1
Knodell, RG; Lindemann, NJ; Peterson, FJ; Steele, NM	1
Goodman, DR; Harbison, RD; James, RC	1
Cavagnaro, J; Rauckman, EJ; Rosen, GM	1
Cavagnaro, J; Kloss, MW; Rauckman, EJ; Rosen, GM	1
Freeman, RW; Harbison, RD; Smith, AC	1
Freeman, RW; Harbison, RD	1
Juvonen, RO; Pasanen, M; Pelkonen, O; Pellinen, P; Raunio, H; Stenbäck, F	1
Holsapple, MP; Jeong, TC; Jordan, SD; Kaminski, EJ; Matulka, RA; Stanulis, ED	1
Pasanen, M; Pelkonen, O; Pellinen, P; Raunio, H; Stenbäck, F	1
Holsapple, MP; Jordan, SD; Matulka, RA; Stanulis, ED	1
Boelsterli, UA	1
Caliendo, MJ; Marshall, W; Moen, MD; Uhler, ML	1
Earnest, D; Eskelson, CD; Odeleye, OE; Watson, RR	1
Chan, AW; Devi, BG	1
Aoki, K; Ohmori, M; Ota, H; Takimoto, M; Yoshida, T	1
Roberts, SM; Salminen, WF; Voellmy, R	1
Bornheim, LM	1
Powers, JF; Shuster, L	1
Aykaç-Toker, G; Calay, Z; Doğru-Abbasoğlu, S; Mutlu-Türkoğlu, U; Oztezcan, S; Uysal, M	1
Ilic, Z; Rosenberg, D; Sell, S; Yin, L	1
Mauboussin, JM; Peyrière, H	1
Aoki, K; Ota, H; Takimoto, M; Yoshida, T	1
Bornheim, LM; Reid, MJ	1
Shaw, K; Shuster, L; Thompson, ML	1
Evans, MA; Harbison, RD	1
Eskelson, CD; Lopez, MC; Odeleye, OE; Smith, BT; Watson, RR	1
Alroy, J; Powers, JF; Shuster, L	1
Eskelson, CD; Pirozhkov, SV; Watson, RR	1
Perper, JA; Van Thiel, DH	1
Luke, BA; Whitten, CG	1
Kreek, MJ; Novick, DM; Tabasco-Minguillan, J	2
Dhumeaux, D; Mallat, A	1
Albores-Saavedra, J; Fernandez, JA; Reddy, KR; Roth, D; Schiff, ER; Silva, MO	1
Blendis, LM; Cameron, R; Dore, S; Gopinath, N; Heathcote, EJ; Levy, G; Tan, J; Wanless, IR	1
Boyer, CS; Petersen, DR	1
Alapati, RS; Batra, SK; Gubbins, GP; Schiffman, RM	1
Cassidy, W; Kanel, GC; Reynolds, TB; Shuster, L	1
Smolen, A; Smolen, TN	1
Boelsterli, UA; Bouis, P	1
Bermes, EW; Jandreski, MA; Kahn, SE; Leischner, R	1
Brendel, K; Conners, S; Krumdieck, CL; Rankin, DR	1
Boyer, CS; Petersen, DR; Ross, D	1
Alarcón, FJ; Bourgoignie, JJ; Fernandez, JA; Preston, RA; Roth, D	1
Levine, JS; Perino, LE; Warren, GH	1

Reviews

8 review(s) available for cocaine and Acute Liver Injury, Drug-Induced

Article	Year
Cocaine-Induced Time-Dependent Alterations in Cytochrome P450 and Liver Function. International journal of molecular sciences, 2023, Jan-13, Volume: 24, Issue:2 Topics: Animals; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 Enzyme System; Humans; Liver; Microsomes, Liver	2023
Cocaine toxicity and hepatic oxidative stress. Current medicinal chemistry, 2012, Volume: 19, Issue:33 Topics: Animals; Chemical and Drug Induced Liver Injury; Cocaine; Dopamine Uptake Inhibitors; Humans; Lipid Peroxidation; Liver; Oxidative Stress; Reactive Oxygen Species	2012
Cocaine-mediated hepatotoxicity. A critical review. Biochemical pharmacology, 1984, Jan-15, Volume: 33, Issue:2 Topics: Animals; Chemical and Drug Induced Liver Injury; Cocaine; Enzymes; Glutathione; Humans; Liver; NADP; Oxidation-Reduction	1984
Genetic determinants of responses to drugs of abuse: an evaluation of research strategies. NIDA research monograph, 1984, Volume: 54 Topics: Animals; Behavior, Animal; Breeding; Chemical and Drug Induced Liver Injury; Cocaine; Corpus Striatum; Dextroamphetamine; Drug Tolerance; Humans; Illicit Drugs; Inbreeding; Mice; Mice, Inbred Strains; Motor Activity; Mutation; Narcotics; Pharmacology; Research Design; Species Specificity; Substance-Related Disorders	1984
The role of CYP enzymes in cocaine-induced liver damage. Archives of toxicology, 1995, Volume: 69, Issue:5 Topics: Animals; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 Enzyme System; Humans	1995
Specific targets of covalent drug-protein interactions in hepatocytes and their toxicological significance in drug-induced liver injury. Drug metabolism reviews, 1993, Volume: 25, Issue:4 Topics: Alkylating Agents; Animals; Chemical and Drug Induced Liver Injury; Cocaine; Glucuronates; Humans; Liver; Protein Binding	1993
Hepatotoxicity associated with cocaine abuse. Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism, 1992, Volume: 10 Topics: Animals; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 Enzyme System; Humans; Risk Factors; Substance-Related Disorders	1992
Cocaine and the liver. Journal of hepatology, 1991, Volume: 12, Issue:3 Topics: Animals; Chemical and Drug Induced Liver Injury; Cocaine; Humans	1991

Other Studies

68 other study(ies) available for cocaine and Acute Liver Injury, Drug-Induced

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Serum liver function profiles in coking workers. American journal of industrial medicine, 1997, Volume: 32, Issue:5 Topics: Adult; Air Pollutants, Occupational; Benzene; Case-Control Studies; Chemical and Drug Induced Liver Injury; Coke; Humans; Linear Models; Liver; Liver Diseases; Liver Function Tests; Logistic Models; Male; Metallurgy; Occupational Exposure; Taiwan	1997
[Effect of work in hot shops at the coke-processing plant on the liver and gastrointestinal tract]. Medycyna pracy, 1989, Volume: 40, Issue:5 Topics: Adult; Air Pollutants, Occupational; Chemical and Drug Induced Liver Injury; Coal; Coke; Female; Gastritis; Gastrointestinal Hemorrhage; Humans; Hydrocarbons; Liver Function Tests; Male; Middle Aged; Occult Blood; Occupational Diseases; Poland	1989
[Pathomorphological picture of various internal organs of rats after long-term exposure to toxic substances in raw coke gas]. Polskie archiwum weterynaryjne, 1987, Volume: 24, Issue:4 Topics: Animals; Chemical and Drug Induced Liver Injury; Coal; Coke; Gases; Kidney; Kidney Diseases; Liver; Liver Diseases; Lung; Lung Diseases; Male; Rats; Rats, Inbred Strains; Time Factors	1987
Episodic Cocaine Use as a Cause of Venous Thromboembolism and Acute Liver Injury. The American journal of case reports, 2023, Oct-24, Volume: 24 Topics: Adult; Anticoagulants; Chemical and Drug Induced Liver Injury; Cocaine; Humans; Male; Pulmonary Embolism; Venous Thromboembolism	2023
Cocaine-induced acute hepatitis: A diagnosis not to forget. Clinics and research in hepatology and gastroenterology, 2021, Volume: 45, Issue:1 Topics: Acute Disease; Adult; Chemical and Drug Induced Liver Injury; Cocaine; Hepatitis; Humans; Male	2021
Protective potential of glutathione peroxidase-1 gene against cocaine-induced acute hepatotoxic consequences in mice. Journal of applied toxicology : JAT, 2018, Volume: 38, Issue:12 Topics: Animals; Antioxidants; Calcium; Chemical and Drug Induced Liver Injury; Cocaine; Cytosol; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Male; Membrane Potential, Mitochondrial; Mice, Knockout; Mitochondria, Liver; Oxidative Stress; Protein Carbonylation; Signal Transduction; Transgenes	2018
Protein kinase Cδ knockout mice are protected from cocaine-induced hepatotoxicity. Chemico-biological interactions, 2019, Jan-05, Volume: 297 Topics: Animals; Chemical and Drug Induced Liver Injury; Cocaine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2; Protein Kinase C-delta	2019
Genetic depletion of p53 attenuates cocaine-induced hepatotoxicity in mice. Biochimie, 2019, Volume: 158 Topics: Alanine Transaminase; Animals; Apoptosis; Apoptosis Regulatory Proteins; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cocaine; Liver; Male; Mice; Mice, Knockout; Oxidative Stress; Protein Kinase C-delta; Tumor Suppressor Protein p53	2019
Significance of alanine aminotransferase levels in patients admitted for cocaine intoxication. Journal of clinical gastroenterology, 2015, Volume: 49, Issue:3 Topics: Acute Kidney Injury; Adolescent; Adult; Alanine Transaminase; Biomarkers; Central Nervous System Stimulants; Chemical and Drug Induced Liver Injury; Clinical Enzyme Tests; Cocaine; Cocaine-Related Disorders; Cross-Sectional Studies; Disease Progression; Female; Humans; Male; Patient Admission; Predictive Value of Tests; Retrospective Studies; Rhabdomyolysis; Risk Factors; Up-Regulation; Young Adult	2015
Increased hepatotoxicity and cardiac fibrosis in cocaine-treated butyrylcholinesterase knockout mice. Basic & clinical pharmacology & toxicology, 2008, Volume: 103, Issue:6 Topics: Animals; Butyrylcholinesterase; Carboxylesterase; Cardiomyopathies; Chemical and Drug Induced Liver Injury; Cocaine; Dose-Response Relationship, Drug; Fibrosis; Liver; Male; Mice; Mice, Knockout; Myocardium; Respiration	2008
Auranofin protects against cocaine-induced hepatic injury through induction of heme oxygenase-1. The Journal of toxicological sciences, 2011, Volume: 36, Issue:5 Topics: Animals; Auranofin; Blotting, Northern; Blotting, Western; Cell Culture Techniques; Cells, Cultured; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Heme Oxygenase-1; Hepatocytes; Humans; Immunohistochemistry; Liver Function Tests; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Knockout; Microsomes, Liver; Protective Agents; Real-Time Polymerase Chain Reaction; Tumor Necrosis Factor-alpha	2011
[Protective effect of 2,4-dihydroxybenzophenone on cocaine-induced hepatotoxicity and neurotoxicity in mice]. Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2012, Jun-18, Volume: 44, Issue:3 Topics: Animals; Antioxidants; Benzophenones; Chemical and Drug Induced Liver Injury; Cocaine; Male; Mice; Mice, Inbred ICR; Neurotoxicity Syndromes	2012
Lipidomic profiling reveals protective function of fatty acid oxidation in cocaine-induced hepatotoxicity. Journal of lipid research, 2012, Volume: 53, Issue:11 Topics: Animals; Chemical and Drug Induced Liver Injury; Chromatography, Liquid; Cocaine; Fatty Acids; In Vitro Techniques; Lipid Metabolism; Liver; Male; Mass Spectrometry; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Palmitoylcarnitine; PPAR alpha	2012
Effects of anti-cocaine vaccine and viral gene transfer of cocaine hydrolase in mice on cocaine toxicity including motor strength and liver damage. Chemico-biological interactions, 2013, Mar-25, Volume: 203, Issue:1 Topics: Animals; Butyrylcholinesterase; Chemical and Drug Induced Liver Injury; Cocaine; Cocaine-Related Disorders; Dependovirus; Gene Transfer Techniques; Genetic Vectors; Humans; Hydrolases; Male; Mice; Mice, Inbred BALB C; Muscle Strength; Rats; Vaccines	2013
Inhibition of cocaine oxidative metabolism attenuates endotoxin potentiation of cocaine mediated hepatotoxicity. Toxicology, 2002, Sep-30, Volume: 179, Issue:1-2 Topics: Animals; Biotransformation; Catalase; Chemical and Drug Induced Liver Injury; Cocaine; Endotoxins; Enzyme Inhibitors; Glutathione; Glutathione Peroxidase; Lipopolysaccharides; Liver; Liver Function Tests; Male; Mice; Oxidation-Reduction; Proadifen	2002
[Cocaine related fulminant liver failure]. Anales de medicina interna (Madrid, Spain : 1984), 2002, Volume: 19, Issue:7 Topics: Adult; Chemical and Drug Induced Liver Injury; Cocaine; Cocaine-Related Disorders; Female; Humans; Liver Failure, Acute; Necrosis	2002
Gender differences in cocaine pharmacokinetics in CF-1 mice. Toxicology letters, 2005, Jan-15, Volume: 155, Issue:1 Topics: Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Cocaine; Female; Indicators and Reagents; Male; Mice; Sex Characteristics; Tissue Distribution	2005
Cocaine-induced acute hepatitis and thrombotic microangiopathy. JAMA, 2005, Feb-16, Volume: 293, Issue:7 Topics: Acute Disease; Adult; Chemical and Drug Induced Liver Injury; Cocaine; Cocaine-Related Disorders; Female; Humans; Thrombocytopenia	2005
Cocaine-induced acute hepatitis and thrombotic microangiopathy. JAMA, 2005, Jun-08, Volume: 293, Issue:22 Topics: Chemical and Drug Induced Liver Injury; Cocaine; Cocaine-Related Disorders; Cryoglobulinemia; Hepatitis C; Humans; Plasma Exchange; Thrombocytopenia	2005
[Effect of roots of Ficus hirta on cocaine-induced hepatotoxicity and active components]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2007, Volume: 32, Issue:12 Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Catalase; Chemical and Drug Induced Liver Injury; Cocaine; Drugs, Chinese Herbal; Ficus; Ficusin; Liver; Liver Diseases; Male; Mice; Mice, Inbred ICR; Plant Roots; Plants, Medicinal; Random Allocation	2007
[Cocaine-induced hepatotoxicity]. Medicina clinica, 2008, Mar-01, Volume: 130, Issue:7 Topics: Acute Disease; Adult; Chemical and Drug Induced Liver Injury; Cocaine; Cocaine-Related Disorders; Humans; Male; Rhabdomyolysis	2008
Cocaine-induced hepatotoxicity: lipid peroxidation as a possible mechanism. Drug and chemical toxicology, 1984, Volume: 7, Issue:4 Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 Enzyme System; Lipid Peroxides; Male; Malondialdehyde; Mice; Mixed Function Oxygenases; Oxidation-Reduction; Phenobarbital	1984
Effect of acute cocaine administration on the metabolism of antipyrine in vivo. Biochemical pharmacology, 1983, Dec-15, Volume: 32, Issue:24 Topics: Animals; Antipyrine; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 Enzyme System; Liver; Male; Mice; Mice, Inbred DBA	1983
Sex and strain differences in response to cocaine. Biochemical pharmacology, 1984, Apr-15, Volume: 33, Issue:8 Topics: Aging; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 Enzyme System; Enzyme Induction; Esterases; Female; Glutathione; Gonadal Steroid Hormones; Male; Mice; Microsomes, Liver; Oxygenases; Sex Factors; Species Specificity	1984
Role of protein binding in cocaine-induced hepatic necrosis. The Journal of pharmacology and experimental therapeutics, 1983, Volume: 224, Issue:1 Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Cocaine; Cricetinae; Esterases; Guinea Pigs; Liver Diseases; Male; Mesocricetus; Mice; Microsomes, Liver; Necrosis; Organ Specificity; Phenobarbital; Protein Binding; Rats; Rats, Inbred Strains; Time Factors	1983
Prevention of acetaminophen and cocaine hepatotoxicity in mice by cimetidine treatment. Gastroenterology, 1983, Volume: 85, Issue:1 Topics: Acetaminophen; Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Cimetidine; Cocaine; Cytochrome P-450 Enzyme System; Guanidines; Kinetics; Liver; Male; Mice; Premedication	1983
Hepatic glutathione and hepatotoxicity: changes induced by selected narcotics. The Journal of pharmacology and experimental therapeutics, 1982, Volume: 221, Issue:3 Topics: Acetaminophen; Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Cocaine; Glutathione; Liver; Male; Mice; Mice, Inbred ICR; Narcotics; Proadifen; Time Factors	1982
Norcocaine nitroxide. A potential hepatotoxic metabolite of cocaine. Molecular pharmacology, 1982, Volume: 21, Issue:2 Topics: Animals; Chemical and Drug Induced Liver Injury; Cocaine; In Vitro Techniques; Kinetics; Microsomes, Liver; NAD; NADP; Oxidation-Reduction; Rats; Rats, Inbred F344	1982
Involvement of FAD-containing monooxygenase in cocaine-induced hepatotoxicity. Toxicology and applied pharmacology, 1982, Jun-15, Volume: 64, Issue:1 Topics: Animals; Biotransformation; Castration; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 Enzyme System; Flavin-Adenine Dinucleotide; Male; Mice; Mice, Inbred C3H; Mixed Function Oxygenases; Oxidoreductases	1982
Acute cocaine-induced hepatotoxicity in DBA/2Ha male mice. Toxicology and applied pharmacology, 1982, Volume: 65, Issue:1 Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 Enzyme System; Glutathione; Liver; Male; Mice; Mice, Inbred DBA; Microsomes, Liver; Mixed Function Oxygenases; Necrosis	1982
Ethanol enhancement of cocaine-induced hepatotoxicity. Biochemical pharmacology, 1981, Mar-01, Volume: 30, Issue:5 Topics: Animals; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Ethanol; Male; Mice; Mice, Inbred ICR	1981
The role of benzoylmethylecgonine in cocaine-induced hepatotoxicity. The Journal of pharmacology and experimental therapeutics, 1981, Volume: 218, Issue:2 Topics: Alanine Transaminase; Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Cocaine; Lidocaine; Male; Mice; Procaine; Rats	1981
Role of metabolism by esterase and cytochrome P-450 in cocaine-induced suppression of the antibody response. The Journal of pharmacology and experimental therapeutics, 1995, Volume: 272, Issue:1 Topics: Animals; Antibody Formation; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 Enzyme System; Diazinon; Enzyme Induction; Esterases; Female; Mice; Microsomes, Liver; Norisoprenoids; Terpenes	1995
Modification of hepatic cytochrome P450 profile by cocaine-induced hepatotoxicity in DBA/2 mouse. European journal of pharmacology, 1994, Nov-01, Volume: 292, Issue:1 Topics: Animals; Aryl Hydrocarbon Hydroxylases; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Dose-Response Relationship, Drug; Enzyme Induction; Liver; Liver Diseases; Liver Regeneration; Male; Mice; Mice, Inbred DBA; Microsomes, Liver; Mixed Function Oxygenases; Time Factors	1994
Cocaine and immunocompetence: possible role of reactive metabolites. Advances in experimental medicine and biology, 1993, Volume: 335 Topics: Animals; Antibody Formation; Chemical and Drug Induced Liver Injury; Cocaine; Dose-Response Relationship, Drug; Female; Immunocompetence; Male; Mice; Mice, Inbred DBA; Procaine; Sex Characteristics; Species Specificity; Spleen	1993
Hepatic rupture in pregnancy associated with cocaine use. Obstetrics and gynecology, 1993, Volume: 82, Issue:4 Pt 2 Sup Topics: Adult; Chemical and Drug Induced Liver Injury; Cocaine; Female; Humans; Pregnancy; Pregnancy Complications; Rupture, Spontaneous	1993
Enhancement of cocaine-induced hepatotoxicity by ethanol. Drug and alcohol dependence, 1993, Volume: 31, Issue:3 Topics: Animals; Chemical and Drug Induced Liver Injury; Cocaine; Drug Synergism; Ethanol; Hepatitis, Alcoholic; Lipid Peroxidation; Liver; Liver Function Tests; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Phospholipids	1993
Impairment of mitochondrial respiration and electron transport chain enzymes during cocaine-induced hepatic injury. Life sciences, 1997, Volume: 60, Issue:11 Topics: Animals; Chemical and Drug Induced Liver Injury; Cocaine; Electron Transport; Energy Metabolism; Lipid Peroxides; Liver Diseases; Male; Mitochondria, Liver; NAD(P)H Dehydrogenase (Quinone); Narcotics; Oxidative Stress; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Time Factors	1997
Cocaine-induced liver injury in mice is mediated by nitric oxide and reactive oxygen species. European journal of pharmacology, 1997, Oct-01, Volume: 336, Issue:1 Topics: Allopurinol; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Cocaine; Enzyme Inhibitors; Guanidines; Liver; Liver Diseases; Male; Mice; Mice, Inbred ICR; Nitric Oxide; Nitric Oxide Synthase; Reactive Oxygen Species	1997
Protection against hepatotoxicity by a single dose of amphetamine: the potential role of heat shock protein induction. Toxicology and applied pharmacology, 1997, Volume: 147, Issue:2 Topics: Acetaminophen; Amphetamine; Animals; Bromobenzenes; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cocaine; Fever; Heat-Shock Proteins; Hyperthermia, Induced; Immunohistochemistry; Liver; Male; Mice; Mice, Inbred ICR	1997
Effect of cytochrome P450 inducers on cocaine-mediated hepatotoxicity. Toxicology and applied pharmacology, 1998, Volume: 150, Issue:1 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carboxylic Ester Hydrolases; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Excitatory Amino Acid Antagonists; Hypnotics and Sedatives; Isoenzymes; Liver; Male; Mice; Narcotics; Phencyclidine; Phenobarbital	1998
Subacute cocaine treatment changes expression of mouse liver cytochrome P450 isoforms. Pharmacology, 1999, Volume: 58, Issue:2 Topics: Animals; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 Enzyme System; Dopamine Uptake Inhibitors; Enzyme Induction; Female; Isoenzymes; Liver; Liver Diseases; Liver Function Tests; Male; Mice; Mice, Inbred BALB C; Rats; Rats, Wistar	1999
The role of stimulated lipid peroxidation and impaired calcium sequestration in the enhancement of cocaine induced hepatotoxicity by ethanol. Drug and alcohol dependence, 2000, Feb-01, Volume: 58, Issue:1-2 Topics: Analysis of Variance; Animals; Calcium; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Cocaine; Drug Synergism; Ethanol; Glutathione; Lipid Peroxidation; Liver; Liver Function Tests; Male; Mice; Mice, Inbred BALB C	2000
Proliferation of hepatic lineage cells of normal C57BL and interleukin-6 knockout mice after cocaine-induced periportal injury. Hepatology (Baltimore, Md.), 2000, Volume: 31, Issue:4 Topics: Alanine Transaminase; alpha-Fetoproteins; Animals; Antigens, CD; Cell Division; Chemical and Drug Induced Liver Injury; Cocaine; Cytokine Receptor gp130; Growth Inhibitors; Interleukin-6; Leukemia Inhibitory Factor; Leukemia Inhibitory Factor Receptor alpha Subunit; Liver; Liver Diseases; Lymphokines; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Necrosis; Portal System; Receptors, Cytokine; Receptors, OSM-LIF; RNA, Messenger	2000
Cocaine-induced acute cytologic hepatitis in HIV-infected patients with nonactive viral hepatitis. Annals of internal medicine, 2000, Jun-20, Volume: 132, Issue:12 Topics: Acute Disease; Administration, Intranasal; Chemical and Drug Induced Liver Injury; Cocaine; Cocaine-Related Disorders; Hepatitis B; Hepatitis C; HIV Infections; Humans	2000
Participation of CYP2A in cocaine-induced hepatotoxicity in female mice. Pharmacology & toxicology, 2000, Volume: 87, Issue:1 Topics: Alanine Transaminase; Animals; Anticonvulsants; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 Enzyme System; Enzyme Activators; Enzyme Induction; Female; Liver Diseases; Mice; Mice, Inbred ICR; Microsomes, Liver; Oxidoreductases, N-Demethylating; Phenobarbital; Steroid Hydroxylases	2000
The effects of phencyclidine pretreatment on cocaine-mediated hepatotoxicity in mice. Toxicology and applied pharmacology, 2001, May-01, Volume: 172, Issue:3 Topics: Animals; Chemical and Drug Induced Liver Injury; Cocaine; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Glutathione; Kinetics; Liver; Liver Diseases; Male; Mice; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidation-Reduction; Phencyclidine	2001
Cocaine-induced hepatic necrosis in mice--the role of cocaine metabolism. Biochemical pharmacology, 1979, Aug-01, Volume: 28, Issue:15 Topics: Acetaminophen; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cocaine; Male; Mice; Mice, Inbred Strains; Necrosis; Phenobarbital; Proadifen; Sleep	1979
Cocaine-induced hepatotoxicity in mice. Toxicology and applied pharmacology, 1978, Volume: 45, Issue:3 Topics: Animals; Chemical and Drug Induced Liver Injury; Cocaine; Dealkylation; Drug Interactions; Enzyme Induction; Female; Glutathione; Liver; Liver Function Tests; Male; Mice; Mixed Function Oxygenases; Rats; Time Factors	1978
Cocaine hepatotoxicity during protein undernutrition of retrovirally infected mice. Canadian journal of physiology and pharmacology, 1992, Volume: 70, Issue:3 Topics: Animals; Body Weight; Chemical and Drug Induced Liver Injury; Cocaine; Female; Leukemia Virus, Murine; Leukemia, Experimental; Lipid Metabolism; Lipid Peroxidation; Liver; Mice; Mice, Inbred C57BL; Organ Size; Protein-Energy Malnutrition; Retroviridae Infections; Steatitis; Transaminases; Triglycerides	1992
Hepatic morphologic and biochemical changes induced by subacute cocaine administration in mice. Toxicologic pathology, 1992, Volume: 20, Issue:1 Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 Enzyme System; Endoplasmic Reticulum; Immunohistochemistry; Liver; Male; Mice; Mice, Inbred A; Mice, Inbred C57BL; Microscopy, Electron; Microsomes, Liver; Mitochondria, Liver; Ribosomes	1992
Chronic ethanol and cocaine-induced hepatotoxicity: effects of vitamin E supplementation. Alcoholism, clinical and experimental research, 1992, Volume: 16, Issue:5 Topics: Animals; Ascorbic Acid; Chemical and Drug Induced Liver Injury; Cocaine; Dose-Response Relationship, Drug; Drug Synergism; Glutathione; Hepatitis, Alcoholic; Hydroxyproline; Lipid Peroxidation; Liver; Male; Mice; Mice, Inbred C57BL; Vitamin E	1992
Liver uptake of Tc-99m PYP. Clinical nuclear medicine, 1991, Volume: 16, Issue:7 Topics: Adult; Chemical and Drug Induced Liver Injury; Cocaine; Humans; Liver; Male; Radionuclide Imaging; Substance-Related Disorders; Technetium Tc 99m Pyrophosphate	1991
Liver function tests in non-parenteral cocaine users. NIDA research monograph, 1990, Volume: 105 Topics: Alcohol Drinking; Chemical and Drug Induced Liver Injury; Cocaine; Humans; Liver Function Tests; Substance-Related Disorders	1990
Hepatic dysfunction accompanying acute cocaine intoxication. Journal of hepatology, 1991, Volume: 12, Issue:3 Topics: Adult; Chemical and Drug Induced Liver Injury; Cocaine; Female; Humans; Liver; Male; Necrosis; Retrospective Studies; Rhabdomyolysis	1991
Histopathology of cocaine hepatotoxicity. Report of four patients. Gastroenterology, 1990, Volume: 98, Issue:2 Topics: Adult; Biopsy; Chemical and Drug Induced Liver Injury; Cocaine; Endoplasmic Reticulum; Female; Humans; Inclusion Bodies; Liver; Male; Microscopy, Electron; Necrosis; Substance-Related Disorders	1990
Potentiation of cocaine-mediated hepatotoxicity by acute and chronic ethanol. Alcoholism, clinical and experimental research, 1990, Volume: 14, Issue:1 Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Cocaine; Drug Synergism; Ethanol; Female; Glutathione; Liver; Male; Mice; Mice, Inbred C3H; Microsomes, Liver; Oxidation-Reduction; Time Factors	1990
Cocaine-induced hepatonephrotoxicity: a case report. Henry Ford Hospital medical journal, 1990, Volume: 38, Issue:1 Topics: Acute Kidney Injury; Adult; Chemical and Drug Induced Liver Injury; Cocaine; Female; Humans	1990
Liver function tests in non-parenteral cocaine users. Drug and alcohol dependence, 1990, Volume: 26, Issue:2 Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cocaine; Hepatitis B; Humans; Liver Diseases, Alcoholic; Liver Function Tests; Substance-Related Disorders	1990
Cocaine-induced liver cell injury: comparison of morphological features in man and in experimental models. Hepatology (Baltimore, Md.), 1990, Volume: 11, Issue:4 Topics: Adult; Animals; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 Enzyme System; Disease Models, Animal; Humans; Liver; Male; Mice; Necrosis; Rhabdomyolysis	1990
Developmental expression of cocaine hepatotoxicity in the mouse. Pharmacology, biochemistry, and behavior, 1990, Volume: 36, Issue:2 Topics: Aging; Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Cocaine; Female; Male; Mice; Mice, Inbred Strains; Sex Factors; Species Specificity; Time Factors	1990
Modulation of cocaine metabolism in primary rat hepatocyte cultures: effects on irreversible binding and protein biosynthesis. Toxicology and applied pharmacology, 1990, Volume: 104, Issue:3 Topics: Analysis of Variance; Animals; Antimetabolites; Aroclors; Buthionine Sulfoximine; Cells, Cultured; Chemical and Drug Induced Liver Injury; Chlorodiphenyl (54% Chlorine); Cocaine; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Glutathione; In Vitro Techniques; L-Lactate Dehydrogenase; Liver; Male; Methionine Sulfoximine; Proteins; Pyridines; Rats; Rats, Inbred Strains	1990
Rhabdomyolysis in a case of free-base cocaine ("crack") overdose. Clinical chemistry, 1989, Volume: 35, Issue:7 Topics: Acute Kidney Injury; Adult; Chemical and Drug Induced Liver Injury; Cocaine; Humans; Male; Rhabdomyolysis; Substance-Related Disorders	1989
Interactive toxicity of cocaine with phenobarbital, morphine and ethanol in organ cultured human and rat liver slices. Proceedings of the Western Pharmacology Society, 1989, Volume: 32 Topics: Animals; Calcium; Chemical and Drug Induced Liver Injury; Cocaine; Drug Interactions; Ethanol; Humans; Liver; Male; Morphine; Organ Culture Techniques; Phenobarbital; Potassium; Rats; Rats, Inbred Strains	1989
Sex and strain differences in the hepatotoxic response to acute cocaine administration in the mouse. Journal of biochemical toxicology, 1988,Winter, Volume: 3 Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Male; Mice; Phenobarbital; Sex Factors; Species Specificity	1988
Acute rhabdomyolysis associated with cocaine intoxication. The New England journal of medicine, 1988, Sep-15, Volume: 319, Issue:11 Topics: Acute Disease; Acute Kidney Injury; Adult; Chemical and Drug Induced Liver Injury; Cocaine; Creatine Kinase; Disseminated Intravascular Coagulation; Female; Humans; Male; Rhabdomyolysis	1988
Cocaine-induced hepatotoxicity in humans. Gastroenterology, 1987, Volume: 93, Issue:1 Topics: Adult; Chemical and Drug Induced Liver Injury; Cocaine; Humans; Liver Diseases; Male; Necrosis; Substance-Related Disorders	1987