cocaine has been researched along with Acute Liver Injury, Drug-Induced in 76 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 22 (28.95) | 18.7374 |
1990's | 28 (36.84) | 18.2507 |
2000's | 13 (17.11) | 29.6817 |
2010's | 10 (13.16) | 24.3611 |
2020's | 3 (3.95) | 2.80 |
Authors | Studies |
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Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Chen, JR; Christiani, DC; Ho, CK; Mao, IF; Wu, MT; Wypij, D | 1 |
Dwornicki, M; Pokrzywnicki, W; Sroczyński, J; Wieja, A | 1 |
Houszka, M; Madej, JA; Peryt, A | 1 |
Daniel, WA; Jastrzębska, J | 1 |
Patel, KH; Stacey, SK; Thomas, KC | 1 |
Bouquet, E; Fauconneau, B; Frouin, E; Lesbordes, M; Pain, S; Pérault-Pochat, MC; Silvain, C | 1 |
Chung, YH; Jang, CG; Jeong, JH; Jung, TW; Kim, DJ; Kim, HC; Lee, SH; Lei, XG; Mai, HN; Nah, SY; Sharma, G; Sharma, N; Shin, EJ | 1 |
Jang, CG; Jeong, JH; Kim, DJ; Kim, HC; Lee, SH; Mai, HN; Nah, SY; Pham, DT; Sharma, G; Sharma, N; Shin, EJ; Trinh, QD | 1 |
Jang, CG; Jeong, JH; Kim, DJ; Kim, HC; Mai, HN; Nah, SY; Pham, DT; Sharma, G; Sharma, N; Shin, EJ; Trinh, QD | 1 |
Barotto, AM; Guollo, F; Narciso-Schiavon, JL; Schiavon, LL; Zannin, M | 1 |
Carlson, M; Duysen, EG; Hinrichs, SH; Li, B; Li, YF; Lockridge, O; Wieseler, S | 1 |
Ashino, T; Iwakura, Y; Kenmotsu, S; Naito-Yamamoto, Y; Numazawa, S; Shioda, S; Sugiuchi, J; Uehara, J; Yoshida, T | 1 |
Jia, FL; Liu, X; Ruan, M; Wu, XY; Xue, R; Zhang, BX | 1 |
Vitcheva, V | 1 |
Chen, C; Gosnell, BA; Shi, X; Yao, D | 1 |
Brimijoin, S; Gao, Y; Geng, L; Kinsey, B; Kosten, TR; Orson, F; Shen, X | 1 |
Abdel-Rahman, MS; Labib, R; Turkall, R | 1 |
Campos Franco, J; González Quintela, A; Martínez Rey, C; Pérez Becerra, E | 1 |
Abdel-Rahman, MS; Turkall, R; Visalli, T | 1 |
Balaguer, F; Fernández, J; Lozano, M; Mas, A; Miquel, R | 1 |
Abd El-Rahman, AM; Ammar, H | 1 |
Cai, QY; Cai, SQ; Chen, HB; Jia, FL; Ou, T; Ruan, M; Zhang, BX; Zhao, ZZ | 1 |
Jiménez Pérez, M; Marín García, D; Olmedo García, R; Santaella Leiva, I | 1 |
Kloss, MW; Rauckman, EJ; Rosen, GM | 2 |
Shuster, L | 1 |
Freeman, RW; Harbison, RD; Teaf, CM | 1 |
Griffeth, LK; Kloss, MW; Rauckman, EJ; Rosen, GM | 1 |
Casey, E; Kanel, GC; Shuster, L; Thompson, ML | 1 |
Evans, MA | 1 |
Knodell, RG; Lindemann, NJ; Peterson, FJ; Steele, NM | 1 |
Goodman, DR; Harbison, RD; James, RC | 1 |
Cavagnaro, J; Rauckman, EJ; Rosen, GM | 1 |
Cavagnaro, J; Kloss, MW; Rauckman, EJ; Rosen, GM | 1 |
Freeman, RW; Harbison, RD; Smith, AC | 1 |
Freeman, RW; Harbison, RD | 1 |
Juvonen, RO; Pasanen, M; Pelkonen, O; Pellinen, P; Raunio, H; Stenbäck, F | 1 |
Holsapple, MP; Jeong, TC; Jordan, SD; Kaminski, EJ; Matulka, RA; Stanulis, ED | 1 |
Pasanen, M; Pelkonen, O; Pellinen, P; Raunio, H; Stenbäck, F | 1 |
Holsapple, MP; Jordan, SD; Matulka, RA; Stanulis, ED | 1 |
Boelsterli, UA | 1 |
Caliendo, MJ; Marshall, W; Moen, MD; Uhler, ML | 1 |
Earnest, D; Eskelson, CD; Odeleye, OE; Watson, RR | 1 |
Chan, AW; Devi, BG | 1 |
Aoki, K; Ohmori, M; Ota, H; Takimoto, M; Yoshida, T | 1 |
Roberts, SM; Salminen, WF; Voellmy, R | 1 |
Bornheim, LM | 1 |
Powers, JF; Shuster, L | 1 |
Aykaç-Toker, G; Calay, Z; Doğru-Abbasoğlu, S; Mutlu-Türkoğlu, U; Oztezcan, S; Uysal, M | 1 |
Ilic, Z; Rosenberg, D; Sell, S; Yin, L | 1 |
Mauboussin, JM; Peyrière, H | 1 |
Aoki, K; Ota, H; Takimoto, M; Yoshida, T | 1 |
Bornheim, LM; Reid, MJ | 1 |
Shaw, K; Shuster, L; Thompson, ML | 1 |
Evans, MA; Harbison, RD | 1 |
Eskelson, CD; Lopez, MC; Odeleye, OE; Smith, BT; Watson, RR | 1 |
Alroy, J; Powers, JF; Shuster, L | 1 |
Eskelson, CD; Pirozhkov, SV; Watson, RR | 1 |
Perper, JA; Van Thiel, DH | 1 |
Luke, BA; Whitten, CG | 1 |
Kreek, MJ; Novick, DM; Tabasco-Minguillan, J | 2 |
Dhumeaux, D; Mallat, A | 1 |
Albores-Saavedra, J; Fernandez, JA; Reddy, KR; Roth, D; Schiff, ER; Silva, MO | 1 |
Blendis, LM; Cameron, R; Dore, S; Gopinath, N; Heathcote, EJ; Levy, G; Tan, J; Wanless, IR | 1 |
Boyer, CS; Petersen, DR | 1 |
Alapati, RS; Batra, SK; Gubbins, GP; Schiffman, RM | 1 |
Cassidy, W; Kanel, GC; Reynolds, TB; Shuster, L | 1 |
Smolen, A; Smolen, TN | 1 |
Boelsterli, UA; Bouis, P | 1 |
Bermes, EW; Jandreski, MA; Kahn, SE; Leischner, R | 1 |
Brendel, K; Conners, S; Krumdieck, CL; Rankin, DR | 1 |
Boyer, CS; Petersen, DR; Ross, D | 1 |
Alarcón, FJ; Bourgoignie, JJ; Fernandez, JA; Preston, RA; Roth, D | 1 |
Levine, JS; Perino, LE; Warren, GH | 1 |
8 review(s) available for cocaine and Acute Liver Injury, Drug-Induced
Article | Year |
---|---|
Cocaine-Induced Time-Dependent Alterations in Cytochrome P450 and Liver Function.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 Enzyme System; Humans; Liver; Microsomes, Liver | 2023 |
Cocaine toxicity and hepatic oxidative stress.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cocaine; Dopamine Uptake Inhibitors; Humans; Lipid Peroxidation; Liver; Oxidative Stress; Reactive Oxygen Species | 2012 |
Cocaine-mediated hepatotoxicity. A critical review.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cocaine; Enzymes; Glutathione; Humans; Liver; NADP; Oxidation-Reduction | 1984 |
Genetic determinants of responses to drugs of abuse: an evaluation of research strategies.
Topics: Animals; Behavior, Animal; Breeding; Chemical and Drug Induced Liver Injury; Cocaine; Corpus Striatum; Dextroamphetamine; Drug Tolerance; Humans; Illicit Drugs; Inbreeding; Mice; Mice, Inbred Strains; Motor Activity; Mutation; Narcotics; Pharmacology; Research Design; Species Specificity; Substance-Related Disorders | 1984 |
The role of CYP enzymes in cocaine-induced liver damage.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 Enzyme System; Humans | 1995 |
Specific targets of covalent drug-protein interactions in hepatocytes and their toxicological significance in drug-induced liver injury.
Topics: Alkylating Agents; Animals; Chemical and Drug Induced Liver Injury; Cocaine; Glucuronates; Humans; Liver; Protein Binding | 1993 |
Hepatotoxicity associated with cocaine abuse.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 Enzyme System; Humans; Risk Factors; Substance-Related Disorders | 1992 |
Cocaine and the liver.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cocaine; Humans | 1991 |
68 other study(ies) available for cocaine and Acute Liver Injury, Drug-Induced
Article | Year |
---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Serum liver function profiles in coking workers.
Topics: Adult; Air Pollutants, Occupational; Benzene; Case-Control Studies; Chemical and Drug Induced Liver Injury; Coke; Humans; Linear Models; Liver; Liver Diseases; Liver Function Tests; Logistic Models; Male; Metallurgy; Occupational Exposure; Taiwan | 1997 |
[Effect of work in hot shops at the coke-processing plant on the liver and gastrointestinal tract].
Topics: Adult; Air Pollutants, Occupational; Chemical and Drug Induced Liver Injury; Coal; Coke; Female; Gastritis; Gastrointestinal Hemorrhage; Humans; Hydrocarbons; Liver Function Tests; Male; Middle Aged; Occult Blood; Occupational Diseases; Poland | 1989 |
[Pathomorphological picture of various internal organs of rats after long-term exposure to toxic substances in raw coke gas].
Topics: Animals; Chemical and Drug Induced Liver Injury; Coal; Coke; Gases; Kidney; Kidney Diseases; Liver; Liver Diseases; Lung; Lung Diseases; Male; Rats; Rats, Inbred Strains; Time Factors | 1987 |
Episodic Cocaine Use as a Cause of Venous Thromboembolism and Acute Liver Injury.
Topics: Adult; Anticoagulants; Chemical and Drug Induced Liver Injury; Cocaine; Humans; Male; Pulmonary Embolism; Venous Thromboembolism | 2023 |
Cocaine-induced acute hepatitis: A diagnosis not to forget.
Topics: Acute Disease; Adult; Chemical and Drug Induced Liver Injury; Cocaine; Hepatitis; Humans; Male | 2021 |
Protective potential of glutathione peroxidase-1 gene against cocaine-induced acute hepatotoxic consequences in mice.
Topics: Animals; Antioxidants; Calcium; Chemical and Drug Induced Liver Injury; Cocaine; Cytosol; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Male; Membrane Potential, Mitochondrial; Mice, Knockout; Mitochondria, Liver; Oxidative Stress; Protein Carbonylation; Signal Transduction; Transgenes | 2018 |
Protein kinase Cδ knockout mice are protected from cocaine-induced hepatotoxicity.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cocaine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2; Protein Kinase C-delta | 2019 |
Genetic depletion of p53 attenuates cocaine-induced hepatotoxicity in mice.
Topics: Alanine Transaminase; Animals; Apoptosis; Apoptosis Regulatory Proteins; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cocaine; Liver; Male; Mice; Mice, Knockout; Oxidative Stress; Protein Kinase C-delta; Tumor Suppressor Protein p53 | 2019 |
Significance of alanine aminotransferase levels in patients admitted for cocaine intoxication.
Topics: Acute Kidney Injury; Adolescent; Adult; Alanine Transaminase; Biomarkers; Central Nervous System Stimulants; Chemical and Drug Induced Liver Injury; Clinical Enzyme Tests; Cocaine; Cocaine-Related Disorders; Cross-Sectional Studies; Disease Progression; Female; Humans; Male; Patient Admission; Predictive Value of Tests; Retrospective Studies; Rhabdomyolysis; Risk Factors; Up-Regulation; Young Adult | 2015 |
Increased hepatotoxicity and cardiac fibrosis in cocaine-treated butyrylcholinesterase knockout mice.
Topics: Animals; Butyrylcholinesterase; Carboxylesterase; Cardiomyopathies; Chemical and Drug Induced Liver Injury; Cocaine; Dose-Response Relationship, Drug; Fibrosis; Liver; Male; Mice; Mice, Knockout; Myocardium; Respiration | 2008 |
Auranofin protects against cocaine-induced hepatic injury through induction of heme oxygenase-1.
Topics: Animals; Auranofin; Blotting, Northern; Blotting, Western; Cell Culture Techniques; Cells, Cultured; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Heme Oxygenase-1; Hepatocytes; Humans; Immunohistochemistry; Liver Function Tests; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Knockout; Microsomes, Liver; Protective Agents; Real-Time Polymerase Chain Reaction; Tumor Necrosis Factor-alpha | 2011 |
[Protective effect of 2,4-dihydroxybenzophenone on cocaine-induced hepatotoxicity and neurotoxicity in mice].
Topics: Animals; Antioxidants; Benzophenones; Chemical and Drug Induced Liver Injury; Cocaine; Male; Mice; Mice, Inbred ICR; Neurotoxicity Syndromes | 2012 |
Lipidomic profiling reveals protective function of fatty acid oxidation in cocaine-induced hepatotoxicity.
Topics: Animals; Chemical and Drug Induced Liver Injury; Chromatography, Liquid; Cocaine; Fatty Acids; In Vitro Techniques; Lipid Metabolism; Liver; Male; Mass Spectrometry; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Palmitoylcarnitine; PPAR alpha | 2012 |
Effects of anti-cocaine vaccine and viral gene transfer of cocaine hydrolase in mice on cocaine toxicity including motor strength and liver damage.
Topics: Animals; Butyrylcholinesterase; Chemical and Drug Induced Liver Injury; Cocaine; Cocaine-Related Disorders; Dependovirus; Gene Transfer Techniques; Genetic Vectors; Humans; Hydrolases; Male; Mice; Mice, Inbred BALB C; Muscle Strength; Rats; Vaccines | 2013 |
Inhibition of cocaine oxidative metabolism attenuates endotoxin potentiation of cocaine mediated hepatotoxicity.
Topics: Animals; Biotransformation; Catalase; Chemical and Drug Induced Liver Injury; Cocaine; Endotoxins; Enzyme Inhibitors; Glutathione; Glutathione Peroxidase; Lipopolysaccharides; Liver; Liver Function Tests; Male; Mice; Oxidation-Reduction; Proadifen | 2002 |
[Cocaine related fulminant liver failure].
Topics: Adult; Chemical and Drug Induced Liver Injury; Cocaine; Cocaine-Related Disorders; Female; Humans; Liver Failure, Acute; Necrosis | 2002 |
Gender differences in cocaine pharmacokinetics in CF-1 mice.
Topics: Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Cocaine; Female; Indicators and Reagents; Male; Mice; Sex Characteristics; Tissue Distribution | 2005 |
Cocaine-induced acute hepatitis and thrombotic microangiopathy.
Topics: Acute Disease; Adult; Chemical and Drug Induced Liver Injury; Cocaine; Cocaine-Related Disorders; Female; Humans; Thrombocytopenia | 2005 |
Cocaine-induced acute hepatitis and thrombotic microangiopathy.
Topics: Chemical and Drug Induced Liver Injury; Cocaine; Cocaine-Related Disorders; Cryoglobulinemia; Hepatitis C; Humans; Plasma Exchange; Thrombocytopenia | 2005 |
[Effect of roots of Ficus hirta on cocaine-induced hepatotoxicity and active components].
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Catalase; Chemical and Drug Induced Liver Injury; Cocaine; Drugs, Chinese Herbal; Ficus; Ficusin; Liver; Liver Diseases; Male; Mice; Mice, Inbred ICR; Plant Roots; Plants, Medicinal; Random Allocation | 2007 |
[Cocaine-induced hepatotoxicity].
Topics: Acute Disease; Adult; Chemical and Drug Induced Liver Injury; Cocaine; Cocaine-Related Disorders; Humans; Male; Rhabdomyolysis | 2008 |
Cocaine-induced hepatotoxicity: lipid peroxidation as a possible mechanism.
Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 Enzyme System; Lipid Peroxides; Male; Malondialdehyde; Mice; Mixed Function Oxygenases; Oxidation-Reduction; Phenobarbital | 1984 |
Effect of acute cocaine administration on the metabolism of antipyrine in vivo.
Topics: Animals; Antipyrine; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 Enzyme System; Liver; Male; Mice; Mice, Inbred DBA | 1983 |
Sex and strain differences in response to cocaine.
Topics: Aging; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 Enzyme System; Enzyme Induction; Esterases; Female; Glutathione; Gonadal Steroid Hormones; Male; Mice; Microsomes, Liver; Oxygenases; Sex Factors; Species Specificity | 1984 |
Role of protein binding in cocaine-induced hepatic necrosis.
Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Cocaine; Cricetinae; Esterases; Guinea Pigs; Liver Diseases; Male; Mesocricetus; Mice; Microsomes, Liver; Necrosis; Organ Specificity; Phenobarbital; Protein Binding; Rats; Rats, Inbred Strains; Time Factors | 1983 |
Prevention of acetaminophen and cocaine hepatotoxicity in mice by cimetidine treatment.
Topics: Acetaminophen; Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Cimetidine; Cocaine; Cytochrome P-450 Enzyme System; Guanidines; Kinetics; Liver; Male; Mice; Premedication | 1983 |
Hepatic glutathione and hepatotoxicity: changes induced by selected narcotics.
Topics: Acetaminophen; Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Cocaine; Glutathione; Liver; Male; Mice; Mice, Inbred ICR; Narcotics; Proadifen; Time Factors | 1982 |
Norcocaine nitroxide. A potential hepatotoxic metabolite of cocaine.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cocaine; In Vitro Techniques; Kinetics; Microsomes, Liver; NAD; NADP; Oxidation-Reduction; Rats; Rats, Inbred F344 | 1982 |
Involvement of FAD-containing monooxygenase in cocaine-induced hepatotoxicity.
Topics: Animals; Biotransformation; Castration; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 Enzyme System; Flavin-Adenine Dinucleotide; Male; Mice; Mice, Inbred C3H; Mixed Function Oxygenases; Oxidoreductases | 1982 |
Acute cocaine-induced hepatotoxicity in DBA/2Ha male mice.
Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 Enzyme System; Glutathione; Liver; Male; Mice; Mice, Inbred DBA; Microsomes, Liver; Mixed Function Oxygenases; Necrosis | 1982 |
Ethanol enhancement of cocaine-induced hepatotoxicity.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Ethanol; Male; Mice; Mice, Inbred ICR | 1981 |
The role of benzoylmethylecgonine in cocaine-induced hepatotoxicity.
Topics: Alanine Transaminase; Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Cocaine; Lidocaine; Male; Mice; Procaine; Rats | 1981 |
Role of metabolism by esterase and cytochrome P-450 in cocaine-induced suppression of the antibody response.
Topics: Animals; Antibody Formation; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 Enzyme System; Diazinon; Enzyme Induction; Esterases; Female; Mice; Microsomes, Liver; Norisoprenoids; Terpenes | 1995 |
Modification of hepatic cytochrome P450 profile by cocaine-induced hepatotoxicity in DBA/2 mouse.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Dose-Response Relationship, Drug; Enzyme Induction; Liver; Liver Diseases; Liver Regeneration; Male; Mice; Mice, Inbred DBA; Microsomes, Liver; Mixed Function Oxygenases; Time Factors | 1994 |
Cocaine and immunocompetence: possible role of reactive metabolites.
Topics: Animals; Antibody Formation; Chemical and Drug Induced Liver Injury; Cocaine; Dose-Response Relationship, Drug; Female; Immunocompetence; Male; Mice; Mice, Inbred DBA; Procaine; Sex Characteristics; Species Specificity; Spleen | 1993 |
Hepatic rupture in pregnancy associated with cocaine use.
Topics: Adult; Chemical and Drug Induced Liver Injury; Cocaine; Female; Humans; Pregnancy; Pregnancy Complications; Rupture, Spontaneous | 1993 |
Enhancement of cocaine-induced hepatotoxicity by ethanol.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cocaine; Drug Synergism; Ethanol; Hepatitis, Alcoholic; Lipid Peroxidation; Liver; Liver Function Tests; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Phospholipids | 1993 |
Impairment of mitochondrial respiration and electron transport chain enzymes during cocaine-induced hepatic injury.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cocaine; Electron Transport; Energy Metabolism; Lipid Peroxides; Liver Diseases; Male; Mitochondria, Liver; NAD(P)H Dehydrogenase (Quinone); Narcotics; Oxidative Stress; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Time Factors | 1997 |
Cocaine-induced liver injury in mice is mediated by nitric oxide and reactive oxygen species.
Topics: Allopurinol; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Cocaine; Enzyme Inhibitors; Guanidines; Liver; Liver Diseases; Male; Mice; Mice, Inbred ICR; Nitric Oxide; Nitric Oxide Synthase; Reactive Oxygen Species | 1997 |
Protection against hepatotoxicity by a single dose of amphetamine: the potential role of heat shock protein induction.
Topics: Acetaminophen; Amphetamine; Animals; Bromobenzenes; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cocaine; Fever; Heat-Shock Proteins; Hyperthermia, Induced; Immunohistochemistry; Liver; Male; Mice; Mice, Inbred ICR | 1997 |
Effect of cytochrome P450 inducers on cocaine-mediated hepatotoxicity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carboxylic Ester Hydrolases; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Excitatory Amino Acid Antagonists; Hypnotics and Sedatives; Isoenzymes; Liver; Male; Mice; Narcotics; Phencyclidine; Phenobarbital | 1998 |
Subacute cocaine treatment changes expression of mouse liver cytochrome P450 isoforms.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 Enzyme System; Dopamine Uptake Inhibitors; Enzyme Induction; Female; Isoenzymes; Liver; Liver Diseases; Liver Function Tests; Male; Mice; Mice, Inbred BALB C; Rats; Rats, Wistar | 1999 |
The role of stimulated lipid peroxidation and impaired calcium sequestration in the enhancement of cocaine induced hepatotoxicity by ethanol.
Topics: Analysis of Variance; Animals; Calcium; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Cocaine; Drug Synergism; Ethanol; Glutathione; Lipid Peroxidation; Liver; Liver Function Tests; Male; Mice; Mice, Inbred BALB C | 2000 |
Proliferation of hepatic lineage cells of normal C57BL and interleukin-6 knockout mice after cocaine-induced periportal injury.
Topics: Alanine Transaminase; alpha-Fetoproteins; Animals; Antigens, CD; Cell Division; Chemical and Drug Induced Liver Injury; Cocaine; Cytokine Receptor gp130; Growth Inhibitors; Interleukin-6; Leukemia Inhibitory Factor; Leukemia Inhibitory Factor Receptor alpha Subunit; Liver; Liver Diseases; Lymphokines; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Necrosis; Portal System; Receptors, Cytokine; Receptors, OSM-LIF; RNA, Messenger | 2000 |
Cocaine-induced acute cytologic hepatitis in HIV-infected patients with nonactive viral hepatitis.
Topics: Acute Disease; Administration, Intranasal; Chemical and Drug Induced Liver Injury; Cocaine; Cocaine-Related Disorders; Hepatitis B; Hepatitis C; HIV Infections; Humans | 2000 |
Participation of CYP2A in cocaine-induced hepatotoxicity in female mice.
Topics: Alanine Transaminase; Animals; Anticonvulsants; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 Enzyme System; Enzyme Activators; Enzyme Induction; Female; Liver Diseases; Mice; Mice, Inbred ICR; Microsomes, Liver; Oxidoreductases, N-Demethylating; Phenobarbital; Steroid Hydroxylases | 2000 |
The effects of phencyclidine pretreatment on cocaine-mediated hepatotoxicity in mice.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cocaine; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Glutathione; Kinetics; Liver; Liver Diseases; Male; Mice; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidation-Reduction; Phencyclidine | 2001 |
Cocaine-induced hepatic necrosis in mice--the role of cocaine metabolism.
Topics: Acetaminophen; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cocaine; Male; Mice; Mice, Inbred Strains; Necrosis; Phenobarbital; Proadifen; Sleep | 1979 |
Cocaine-induced hepatotoxicity in mice.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cocaine; Dealkylation; Drug Interactions; Enzyme Induction; Female; Glutathione; Liver; Liver Function Tests; Male; Mice; Mixed Function Oxygenases; Rats; Time Factors | 1978 |
Cocaine hepatotoxicity during protein undernutrition of retrovirally infected mice.
Topics: Animals; Body Weight; Chemical and Drug Induced Liver Injury; Cocaine; Female; Leukemia Virus, Murine; Leukemia, Experimental; Lipid Metabolism; Lipid Peroxidation; Liver; Mice; Mice, Inbred C57BL; Organ Size; Protein-Energy Malnutrition; Retroviridae Infections; Steatitis; Transaminases; Triglycerides | 1992 |
Hepatic morphologic and biochemical changes induced by subacute cocaine administration in mice.
Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 Enzyme System; Endoplasmic Reticulum; Immunohistochemistry; Liver; Male; Mice; Mice, Inbred A; Mice, Inbred C57BL; Microscopy, Electron; Microsomes, Liver; Mitochondria, Liver; Ribosomes | 1992 |
Chronic ethanol and cocaine-induced hepatotoxicity: effects of vitamin E supplementation.
Topics: Animals; Ascorbic Acid; Chemical and Drug Induced Liver Injury; Cocaine; Dose-Response Relationship, Drug; Drug Synergism; Glutathione; Hepatitis, Alcoholic; Hydroxyproline; Lipid Peroxidation; Liver; Male; Mice; Mice, Inbred C57BL; Vitamin E | 1992 |
Liver uptake of Tc-99m PYP.
Topics: Adult; Chemical and Drug Induced Liver Injury; Cocaine; Humans; Liver; Male; Radionuclide Imaging; Substance-Related Disorders; Technetium Tc 99m Pyrophosphate | 1991 |
Liver function tests in non-parenteral cocaine users.
Topics: Alcohol Drinking; Chemical and Drug Induced Liver Injury; Cocaine; Humans; Liver Function Tests; Substance-Related Disorders | 1990 |
Hepatic dysfunction accompanying acute cocaine intoxication.
Topics: Adult; Chemical and Drug Induced Liver Injury; Cocaine; Female; Humans; Liver; Male; Necrosis; Retrospective Studies; Rhabdomyolysis | 1991 |
Histopathology of cocaine hepatotoxicity. Report of four patients.
Topics: Adult; Biopsy; Chemical and Drug Induced Liver Injury; Cocaine; Endoplasmic Reticulum; Female; Humans; Inclusion Bodies; Liver; Male; Microscopy, Electron; Necrosis; Substance-Related Disorders | 1990 |
Potentiation of cocaine-mediated hepatotoxicity by acute and chronic ethanol.
Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Cocaine; Drug Synergism; Ethanol; Female; Glutathione; Liver; Male; Mice; Mice, Inbred C3H; Microsomes, Liver; Oxidation-Reduction; Time Factors | 1990 |
Cocaine-induced hepatonephrotoxicity: a case report.
Topics: Acute Kidney Injury; Adult; Chemical and Drug Induced Liver Injury; Cocaine; Female; Humans | 1990 |
Liver function tests in non-parenteral cocaine users.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cocaine; Hepatitis B; Humans; Liver Diseases, Alcoholic; Liver Function Tests; Substance-Related Disorders | 1990 |
Cocaine-induced liver cell injury: comparison of morphological features in man and in experimental models.
Topics: Adult; Animals; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 Enzyme System; Disease Models, Animal; Humans; Liver; Male; Mice; Necrosis; Rhabdomyolysis | 1990 |
Developmental expression of cocaine hepatotoxicity in the mouse.
Topics: Aging; Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Cocaine; Female; Male; Mice; Mice, Inbred Strains; Sex Factors; Species Specificity; Time Factors | 1990 |
Modulation of cocaine metabolism in primary rat hepatocyte cultures: effects on irreversible binding and protein biosynthesis.
Topics: Analysis of Variance; Animals; Antimetabolites; Aroclors; Buthionine Sulfoximine; Cells, Cultured; Chemical and Drug Induced Liver Injury; Chlorodiphenyl (54% Chlorine); Cocaine; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Glutathione; In Vitro Techniques; L-Lactate Dehydrogenase; Liver; Male; Methionine Sulfoximine; Proteins; Pyridines; Rats; Rats, Inbred Strains | 1990 |
Rhabdomyolysis in a case of free-base cocaine ("crack") overdose.
Topics: Acute Kidney Injury; Adult; Chemical and Drug Induced Liver Injury; Cocaine; Humans; Male; Rhabdomyolysis; Substance-Related Disorders | 1989 |
Interactive toxicity of cocaine with phenobarbital, morphine and ethanol in organ cultured human and rat liver slices.
Topics: Animals; Calcium; Chemical and Drug Induced Liver Injury; Cocaine; Drug Interactions; Ethanol; Humans; Liver; Male; Morphine; Organ Culture Techniques; Phenobarbital; Potassium; Rats; Rats, Inbred Strains | 1989 |
Sex and strain differences in the hepatotoxic response to acute cocaine administration in the mouse.
Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Male; Mice; Phenobarbital; Sex Factors; Species Specificity | 1988 |
Acute rhabdomyolysis associated with cocaine intoxication.
Topics: Acute Disease; Acute Kidney Injury; Adult; Chemical and Drug Induced Liver Injury; Cocaine; Creatine Kinase; Disseminated Intravascular Coagulation; Female; Humans; Male; Rhabdomyolysis | 1988 |
Cocaine-induced hepatotoxicity in humans.
Topics: Adult; Chemical and Drug Induced Liver Injury; Cocaine; Humans; Liver Diseases; Male; Necrosis; Substance-Related Disorders | 1987 |