Compounds > cocaethylene
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cocaethylene and Cocaine Abuse

cocaethylene has been researched along with Cocaine Abuse in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (7.41)18.2507
2000's13 (48.15)29.6817
2010's10 (37.04)24.3611
2020's2 (7.41)2.80

Authors

AuthorsStudies
Helander, A; Signell, P; Villén, T1
Hartwig, S; Krumbiegel, F; Methling, M; Niebel, A; Pragst, F; Thurmann, D; Westendorf, L1
Aranguren, M; Gorlelo, JC; Krumbiegel, F; Nagel, A; Poliansky, N; Pragst, F; Rubio, NC; Thurmann, D; Zytowski, E1
Aroni, K; Fucci, N; Gambelunghe, C; Rossi, R1
Hou, S; Zhan, CG; Zhan, M; Zheng, F; Zheng, X1
Gonzalez, J; Hastedt, M; Pragst, F; Rubio, NC1
Alcalde, M; Brugada, R; Campuzano, O; Carbone, A; Cittadini, F; De Giovanni, N; Oliva, A; Partemi, S1
Aroni, K; Bacci, M; Fucci, N; Gambelunghe, C; Gili, A; Pascali, V; Rossi, R1
Laizure, SC; Parker, RB1
Bhatt, A; Farooq, MU; Patel, M1
Calaycay, J; Moon, CH; Rushbrook, JI; Subramanian, RA; Sutijono, D; Wiener, SE; Zehtabchi, S1
Bertol, E; Del Bravo, E; Furlanetto, S; Mari, F; Politi, L1
Alves De Melo, F; Kinsey, BM; Kosten, TR; Ladbury, JE; Orson, FM; Ramakrishnan, M1
Gianvecchio, VA; Leyton, V; Munoz, DR; Osselton, MD; Pounder, DJ; Rees, KA; Seulin, S; Yonamine, M1
Leccese, AP; Pennings, EJ; Wolff, FA1
Charbit, B; Lepere, B1
Antonilli, L; Cioce, AM; Giudici, FD; Grassi, MC; Nencini, P1
Morini, L; Polettini, A; Politi, L; Stramesi, C; Zucchella, A1
Baker, J; Jatlow, P; McCance-Katz, EF; Pade, P; Ramakrishnan, V1
Bradberry, CW; Heitz, RP; Liu, S; Sampson, AR; Zhang, W1
Cami, J; de la Torre, R; Farré, M; González, ML; Segura, J1
Bradberry, CW; Jatlow, P; Lee, T1
Hart, CL; Jatlow, P; McCance-Katz, EF; Sevarino, KA1
Clauwaert, KM; De Leenheer, AP; Lambert, WE; Van Bocxlaer, JF1
Davis, GG; Embry, JH; Gruszecki, AC; Robinson, CA1
Bourland, JA; Hatab, MM; Hayes, EF; Kelly, RC; Sweeney, SA1
Dorbandt, A; Garvey, L; Jeromin, J; Wilson, LD1

Reviews

2 review(s) available for cocaethylene and Cocaine Abuse

ArticleYear
Effects of concurrent use of alcohol and cocaine.
    Addiction (Abingdon, England), 2002, Volume: 97, Issue:7

    Topics: Alcohol-Related Disorders; Cocaine; Cocaine-Related Disorders; Cognition Disorders; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Health Surveys; Heart Rate; Humans; Prospective Studies; Retrospective Studies; Violence

2002
Cocaine metabolism in humans after use of alcohol. Clinical and research implications.
    Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism, 1998, Volume: 14

    Topics: Alcohol Drinking; Animals; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; Humans; Metabolic Clearance Rate

1998

Trials

3 trial(s) available for cocaethylene and Cocaine Abuse

ArticleYear
Short-term efficacy of Disulfiram or Naltrexone in reducing positive urinalysis for both cocaine and cocaethylene in cocaine abusers: a pilot study.
    Pharmacological research, 2007, Volume: 55, Issue:2

    Topics: Adult; Cocaine; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Combined Modality Therapy; Disulfiram; Humans; Naltrexone; Narcotic Antagonists; Patient Compliance; Pilot Projects; Time Factors; Treatment Outcome

2007
Acute cocaine responses following cocaethylene infusion.
    The American journal of drug and alcohol abuse, 2007, Volume: 33, Issue:4

    Topics: Adult; Behavior, Addictive; Blood Pressure; Cocaine; Cocaine-Related Disorders; Double-Blind Method; Drug Interactions; Drug Tolerance; Female; Heart Rate; Hospitalization; Humans; Infusions, Intravenous; Male; Placebos; Treatment Outcome

2007
Comparison of intravenous cocaethylene and cocaine in humans.
    Psychopharmacology, 2000, Volume: 149, Issue:2

    Topics: Adult; Blood Pressure; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Double-Blind Method; Female; Heart Rate; Humans; Injections, Intravenous; Male; Vasoconstrictor Agents

2000

Other Studies

22 other study(ies) available for cocaethylene and Cocaine Abuse

ArticleYear
Urine Drug Tests Indicate Higher Prevalence of Combined Alcohol and Cocaine Use Compared to Alcohol Together with Cannabis or Amphetamine-A Possible Link to Cocaethylene.
    Alcohol and alcoholism (Oxford, Oxfordshire), 2023, May-09, Volume: 58, Issue:3

    Topics: Amphetamine; Cannabis; Chromatography, Liquid; Cocaine; Cocaine-Related Disorders; Ethanol; Humans; Prevalence; Retrospective Studies; Tandem Mass Spectrometry

2023
Positive findings of ethyl glucuronide in hair of young children from families with addiction background.
    International journal of legal medicine, 2020, Volume: 134, Issue:2

    Topics: Adolescent; Alcohol Drinking; Behavior, Addictive; Biomarkers; Child; Child, Preschool; Chromatography, Liquid; Cocaine; Cocaine-Related Disorders; Female; Glucuronates; Hair; Humans; Infant; Male; Minors; Palmitic Acids; Parents; Substance Abuse Detection; Tandem Mass Spectrometry

2020
Discrimination between chewing of coca leaves or drinking of coca tea and smoking of "paco" (coca paste) by hair analysis. A preliminary study of possibilities and limitations.
    Forensic science international, 2019, Volume: 297

    Topics: Acetone; Adolescent; Adult; Biomarkers; Coca; Cocaine; Cocaine-Related Disorders; Female; Hair; Humans; Male; Mastication; Middle Aged; Plant Leaves; Pyrrolidines; Smoking; Substance Abuse Detection; Tea; Young Adult

2019
A direct immersion solid-phase microextraction gas chromatography/mass spectrometry method for the simultaneous detection of levamisole and minor cocaine congeners in hair samples from chronic abusers.
    Therapeutic drug monitoring, 2014, Volume: 36, Issue:6

    Topics: Chronic Disease; Cocaine; Cocaine-Related Disorders; Gas Chromatography-Mass Spectrometry; Hair; Humans; Levamisole; Solid Phase Microextraction

2014
Kinetic characterization of human butyrylcholinesterase mutants for the hydrolysis of cocaethylene.
    The Biochemical journal, 2014, Jun-15, Volume: 460, Issue:3

    Topics: Animals; Butyrylcholinesterase; Catalysis; CHO Cells; Cocaine; Cocaine-Related Disorders; Cricetulus; Ethanol; HEK293 Cells; Humans; Hydrolysis; Kinetics; Male; Molecular Docking Simulation; Rats

2014
Possibilities for discrimination between chewing of coca leaves and abuse of cocaine by hair analysis including hygrine, cuscohygrine, cinnamoylcocaine and cocaine metabolite/cocaine ratios.
    International journal of legal medicine, 2015, Volume: 129, Issue:1

    Topics: Acetaminophen; Acetone; Adolescent; Adult; Aged; Chromatography, Liquid; Coca; Cocaine; Cocaine-Related Disorders; Drug and Narcotic Control; Drug Contamination; Female; Forensic Toxicology; Hair; Humans; Levamisole; Lidocaine; Male; Mass Spectrometry; Mastication; Middle Aged; Plant Leaves; Pyrrolidines; Tea

2015
Genetic and toxicologic investigation of Sudden Cardiac Death in a patient with Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) under cocaine and alcohol effects.
    International journal of legal medicine, 2015, Volume: 129, Issue:1

    Topics: Adult; Arrhythmogenic Right Ventricular Dysplasia; Central Nervous System Depressants; Cocaine; Cocaine-Related Disorders; Death, Sudden, Cardiac; Desmoglein 2; Electrocardiography; Ethanol; Forensic Toxicology; Hair; Heart Arrest; Humans; Male; Mutation; Narcotics; Tachycardia, Sinus

2015
Norcocaine and cocaethylene distribution patterns in hair samples from light, moderate, and heavy cocaine users.
    Drug testing and analysis, 2017, Volume: 9, Issue:2

    Topics: Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Female; Gas Chromatography-Mass Spectrometry; Hair; Humans; Limit of Detection; Male; Solid Phase Extraction; Substance Abuse Detection

2017
Pharmacodynamic evaluation of the cardiovascular effects after the coadministration of cocaine and ethanol.
    Drug metabolism and disposition: the biological fate of chemicals, 2009, Volume: 37, Issue:2

    Topics: Alcoholism; Animals; Anti-Arrhythmia Agents; Blood Pressure; Cardiovascular System; Cocaine; Cocaine-Related Disorders; Dogs; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Electrocardiography; Ethanol; Heart Rate; Models, Animal; Myocardial Contraction

2009
Neurotoxic and cardiotoxic effects of cocaine and ethanol.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2009, Volume: 5, Issue:3

    Topics: Adult; Alcoholism; Anti-Arrhythmia Agents; Aphasia; Brain; Carotid Artery, Internal, Dissection; Cerebral Angiography; Cerebral Infarction; Cocaine; Cocaine-Related Disorders; Combined Modality Therapy; Craniotomy; Decompression, Surgical; Electric Countershock; Electrocardiography; Female; Heart Rate; Hemiplegia; Humans; Magnesium Sulfate; Magnetic Resonance Angiography; Tomography, X-Ray Computed; Torsades de Pointes; Treatment Outcome; Ventricular Fibrillation

2009
Patients with detectable cocaethylene are more likely to require intensive care unit admission after trauma.
    The American journal of emergency medicine, 2010, Volume: 28, Issue:9

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Alcohol Drinking; Chi-Square Distribution; Cocaine; Cocaine-Related Disorders; Critical Care; Female; Humans; Injury Severity Score; Length of Stay; Logistic Models; Male; Middle Aged; Patient Admission; Sex Factors; Statistics, Nonparametric; Wounds and Injuries; Young Adult

2010
Determination of fatty acid ethyl esters in hair by GC-MS and application in a population of cocaine users.
    Journal of pharmaceutical and biomedical analysis, 2011, Apr-05, Volume: 54, Issue:5

    Topics: Alcoholism; Biomarkers; Calibration; Cocaine; Cocaine-Related Disorders; Esters; Fatty Acids; Gas Chromatography-Mass Spectrometry; Hair; Humans; Reproducibility of Results; Substance Abuse Detection

2011
Probing cocaine-antibody interactions in buffer and human serum.
    PloS one, 2012, Volume: 7, Issue:7

    Topics: Animals; Antibodies, Monoclonal, Murine-Derived; Antibody Affinity; Binding, Competitive; Calorimetry; Cattle; Cocaine; Cocaine-Related Disorders; Humans; Immobilized Proteins; Immunotherapy; Kinetics; Mice; Protein Binding; Serum; Serum Albumin; Serum Albumin, Bovine; Surface Plasmon Resonance

2012
Analysis of skeletal muscle has potential value in the assessment of cocaine-related deaths.
    Forensic science international, 2013, Mar-10, Volume: 226, Issue:1-3

    Topics: Adolescent; Adult; Cocaine; Cocaine-Related Disorders; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Male; Myocardium; Narcotics; Quadriceps Muscle; Substance Abuse Detection; Vitreous Body; Young Adult

2013
Cardiovascular complications of cocaine use: recent points on cocaethylene toxicity.
    Annales de medecine interne, 2002, Volume: 153, Issue:3 Suppl

    Topics: Affect; Alcohol Drinking; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Drug Interactions; Humans

2002
Markers of chronic alcohol use in hair: comparison of ethyl glucuronide and cocaethylene in cocaine users.
    Forensic science international, 2007, Oct-02, Volume: 172, Issue:1

    Topics: Adolescent; Adult; Alcoholism; Biomarkers; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Female; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Glucuronates; Hair; Humans; Male; Middle Aged; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection

2007
Evidence of temporal cortical dysfunction in rhesus monkeys following chronic cocaine self-administration.
    Cerebral cortex (New York, N.Y. : 1991), 2008, Volume: 18, Issue:9

    Topics: Animals; Chronic Disease; Cocaine; Cocaine-Related Disorders; Cognition Disorders; Conditioning, Psychological; Discrimination, Psychological; Dopamine Uptake Inhibitors; Female; Macaca mulatta; Male; Prefrontal Cortex; Psychomotor Performance; Reversal Learning; Self Administration

2008
Rapid induction of behavioral and neurochemical tolerance to cocaethylene, a model compound for agonist therapy of cocaine dependence.
    Psychopharmacology, 1999, Sep-01, Volume: 146, Issue:1

    Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Dopamine; Drug Tolerance; Male; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley

1999
Segmental analysis for cocaine and metabolites by HPLC in hair of suspected drug overdose cases.
    Forensic science international, 2000, Jun-05, Volume: 110, Issue:3

    Topics: Chromatography, High Pressure Liquid; Cocaine; Cocaine-Related Disorders; Drug Overdose; Forensic Medicine; Hair; Humans

2000
Correlation of the incidence of cocaine and cocaethylene in hair and postmortem biologic samples.
    The American journal of forensic medicine and pathology, 2000, Volume: 21, Issue:2

    Topics: Autopsy; Cocaine; Cocaine-Related Disorders; Enzyme Multiplied Immunoassay Technique; Ethanol; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Hair; Humans; Prospective Studies

2000
Quantitation of cocaine, benzoylecgonine, cocaethylene, methylecgonine, and norcocaine in human hair by positive ion chemical ionization (PICI) gas chromatography-tandem mass spectrometry.
    Journal of analytical toxicology, 2000, Volume: 24, Issue:7

    Topics: Biotransformation; Cocaine; Cocaine-Related Disorders; Crack Cocaine; Gas Chromatography-Mass Spectrometry; Hair; Humans; Reproducibility of Results; Substance Abuse Detection

2000
Cocaine, ethanol, and cocaethylene cardiotoxity in an animal model of cocaine and ethanol abuse.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2001, Volume: 8, Issue:3

    Topics: Alcoholism; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Cardiac Output; Cardiomyopathies; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dogs; Electrocardiography; Ethanol; Prospective Studies; Randomized Controlled Trials as Topic; Time Factors; Ventricular Pressure

2001