cobaltous chloride has been researched along with Disease Models, Animal in 64 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (4.69) | 18.7374 |
| 1990's | 2 (3.13) | 18.2507 |
| 2000's | 12 (18.75) | 29.6817 |
| 2010's | 36 (56.25) | 24.3611 |
| 2020's | 11 (17.19) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, YS; Hsieh, ST; Wang, YC | 1 |
| Behar-Cohen, F; Bigot, K; Bordet, T; Fan, Y; Inman, DM; Jaworski, T; Kodati, B; Nsiah, NY; Pappenhagen, N; Picard, E; Youale, J | 1 |
| Bian, Y; Hou, Y; Huang, L; Li, J; Li, Y; Qiao, C; Song, G | 1 |
| Arab, JP; Arrese, M; Barrera, F; Cabrera, D; Geng, Y; Hernández, A; Moshage, H; Sepúlveda, R; Solís, N; Torres, J | 1 |
| Bai, J; Cheng, L; Gao, X; Qi, X; Zhao, J | 1 |
| Aasbrenn, M; Abd El-Aty, AM; Abdu, A; Abraha, HB; Achour, A; Acquaroni, M; Addeo, P; Agback, P; Agback, T; Al-Alwan, M; Al-Mazrou, A; Al-Mohanna, F; Aliste, M; Almquist, J; Andel, J; Ando, M; Angelov, A; Annuar, MSM; Antwi, K; Arroliga, AC; Arruda, SLM; Asch, SM; Averous, G; Ayaz, S; Ayer, GB; Bachellier, P; Ball, S; Banijamali, AR; Barden, TC; Bartoncini, S; Bedanie, G; Bellò, M; Benić, F; Berhe, GG; Bertiger, G; Beumer, JH; Bhandari, B; Bond, DS; Boules, M; Braüner Christensen, J; Brown-Johnson, C; Burgstaller, S; Cao, L; Capasso, C; Carlevato, R; Carvalho, AE; Ceci, F; Chagas, ATA; Chavan, SG; Chen, AP; Chen, HC; Chen, J; Chen, Q; Chen, Y; Chen, YF; Christ, ER; Chu, CW; Covey, JM; Coyne, GO'; Cristea, MC; Currie, MG; Dahdal, DN; Dai, L; Dang, Z; de Abreu, NL; de Carvalho, KMB; de la Plaza Llamas, R; Deandreis, D; Del Prete, S; Dennis, JA; Deur, J; Díaz Candelas, DA; Divyapriya, G; Djanani, A; Dodig, D; Doki, Y; Doroshow, JH; Dos Santos, RC; Durairaj, N; Dutra, ES; Eguchi, H; Eisterer, W; Ekmann, A; Elakkad, A; Evans, WE; Fan, W; Fang, Z; Faria, HP; Farris, SG; Fenoll, J; Fernandez-Botran, R; Flores, P; Fujita, J; Gan, L; Gandara, DR; Gao, X; Garcia, AA; Garrido, I; Gebru, HA; Gerger, A; Germano, P; Ghamande, S; Ghebeh, H; Giver Jensen, T; Go, A; Goichot, B; Goldwater, M; Gontero, P; Greil, R; Gruenberger, B; Guarneri, A; Guo, Y; Gupta, S; Haxholdt Lunn, T; Hayek, AJ; He, ML; Hellín, P; Hepprich, M; Hernández de Rodas, E; Hill, A; Hndeya, AG; Holdsworth, LM; Hookey, L; Howie, W; Hu, G; Huang, JD; Huang, SY; Hubmann, E; Hwang, SY; Imamura, H; Imperiale, A; Jiang, JQ; Jimenez, JL; Jin, F; Jin, H; Johnson, KL; Joseph, A; Juwara, L; Kalapothakis, E; Karami, H; Karayağiz Muslu, G; Kawabata, R; Kerwin, J; Khan, I; Khin, S; Kidanemariam, HG; Kinders, RJ; Klepov, VV; Koehler, S; Korger, M; Kovačić, S; Koyappayil, A; Kroll, MH; Kuban, J; Kummar, S; Kung, HF; Kurokawa, Y; Laengle, F; Lan, J; Leal, HG; Lee, MH; Lemos, KGE; Li, B; Li, G; Li, H; Li, X; Li, Y; Li, Z; Liebl, W; Lillaz, B; Lin, F; Lin, L; Lin, MCM; Lin, Y; Lin, YP; Lipton, RB; Liu, J; Liu, W; Liu, Z; Lu, J; Lu, LY; Lu, YJ; Ludwig, S; Luo, Y; Ma, L; Ma, W; Machado-Coelho, GLL; Mahmoodi, B; Mahoney, M; Mahvash, A; Mansour, FA; Mao, X; Marinho, CC; Masferrer, JL; Matana Kaštelan, Z; Melendez-Araújo, MS; Méndez-Chacón, E; Miletić, D; Miller, B; Miller, E; Miller, SB; Mo, L; Moazzen, M; Mohammadniaei, M; Montaz-Rosset, MS; Mousavi Khaneghah, A; Mühlethaler, K; Mukhopadhyay, S; Mulugeta, A; Nambi, IM; Navarro, S; Nazmara, S; Neumann, HJ; Newman, EM; Nguyen, HTT; Nicolato, AJPG; Nicolotti, DG; Nieva, JJ; Nilvebrant, J; Nocentini, A; Nugent, K; Nunez-Rodriguez, DL; Nygren, PÅ; Oberli, A; Oderda, M; Odisio, B; Oehler, L; Otludil, B; Overman, M; Özdemir, M; Pace, KA; Palm, H; Parchment, RE; Parise, R; Passera, R; Pavlovic, J; Pecherstorfer, M; Peng, Z; Pérez Coll, C; Petzer, A; Philipp-Abbrederis, K; Pichler, P; Piekarz, RL; Pilati, E; Pimentel, JDSM; Posch, F; Prager, G; Pressel, E; Profy, AT; Qi, P; Qi, Y; Qiu, C; Rajasekhar, B; Ramia, JM; Raynor, HA; Reis, VW; Reubi, JC; Ricardi, U; Riedl, JM; Romano, F; Rong, X; Rubinstein, L; Rumboldt, Z; Sabir, S; Safaeinili, N; Sala, BM; Sandoval Castillo, L; Sau, M; Sbhatu, DB; Schulte, T; Scott, V; Shan, H; Shao, Y; Shariatifar, N; Shaw, JG; She, Y; Shen, B; Shernyukov, A; Sheth, RA; Shi, B; Shi, R; Shum, KT; Silva, JC; Singh, A; Sinha, N; Sirajudeen, AAO; Slaven, J; Sliwa, T; Somme, F; Song, S; Steinberg, SM; Subramaniam, R; Suetta, C; Sui, Y; Sun, B; Sun, C; Sun, H; Sun, Y; Supuran, CT; Surger, M; Svartz, G; Takahashi, T; Takeno, A; Tam, AL; Tang, Z; Tanner, JA; Tannich, E; Taye, MG; Tekle, HT; Thomas, GJ; Tian, Y; Tobin, JV; Todd Milne, G; Tong, X; Une, C; Vela, N; Venkateshwaran, U; Villagrán de Tercero, CI; Wakefield, JD; Wampfler, R; Wan, M; Wang, C; Wang, J; Wang, L; Wang, S; Waser, B; Watt, RM; Wei, B; Wei, L; Weldemichael, MY; Wellmann, IA; Wen, A; Wild, D; Wilthoner, K; Winder, T; Wing, RR; Winget, M; Wöll, E; Wong, KL; Wong, KT; Wu, D; Wu, Q; Wu, Y; Xiang, T; Xiang, Z; Xu, F; Xu, L; Yamasaki, M; Yamashita, K; Yan, H; Yan, Y; Yang, C; Yang, H; Yang, J; Yang, N; Yang, Y; Yau, P; Yu, M; Yuan, Q; Zhan, S; Zhang, B; Zhang, H; Zhang, J; Zhang, N; Zhang, Y; Zhao, X; Zheng, BJ; Zheng, H; Zheng, W; Zhou, H; Zhou, X; Zhu, S; Zimmer, DP; Zionts, D; Zitella, A; Zlott, J; Zolfaghari, K; Zuo, D; Zur Loye, HC; Žuža, I | 1 |
| Arab, JP; Arrese, M; Buist-Homan, M; Cabrera, D; Geng, Y; Hernández, A; Moshage, H; Reyes, D; Sepulveda, R; Solis, N | 1 |
| Gao, G; Li, B; Li, M; Wang, K; Xia, N; Xie, Y | 1 |
| Cai, X; Li, S; Li, T; Wang, X; Wu, Q; Xu, B; Zhang, H | 1 |
| Jeong, H; Kawagishi, H; Kurihara, T; Lee, D; Miwa, Y; Shoda, C; Tsubota, K; Wu, J | 1 |
| Anésio, A; Bianchi, PC; Carneiro-de-Oliveira, PE; Cruz, FC; Engi, SA; Felipe, JM; Leão, RM; Palombo, P; Planeta, CDS; Yokoyama, TS; Zaniboni, CR | 1 |
| Ibuki, M; Kurihara, T; Lee, D; Miwa, Y; Shinojima, A; Tsubota, K | 1 |
| Chen, G; Chen, M; Chen, Q; Cheng, L; Gu, N; Li, C; Lu, J; Pei, Y; Tian, W; Wang, J; Wang, X | 1 |
| Duan, XC; Fang, ZH; Liu, MM; Wu, YJ; Zhao, JD | 1 |
| Chen, D; Chen, Z; Dai, C; Han, Z; He, F; Li, Y; Tan, R; Tian, H; Wang, G; Wang, M; Wei, L; Yang, B; Yang, H; Zhang, B | 1 |
| Chiu, S; Fan, XL; Fang, SB; Fu, QL; Jiang, D; Li, X; Lian, Q; Tse, HF; Xu, ZB; Yao, Y; Zhang, Y | 1 |
| Jiang, J; Li, Z; Wang, M; Wang, W; Yan, M; Zheng, Y | 1 |
| Fujii, M; Hu, Q; Krafft, PR; Soejima, Y; Tang, J; Zhang, JH | 1 |
| Arai, K; Ayata, C; Boas, D; Hayakawa, K; Kim, KW; Lo, EH; Magnain, C; Matsuzaki, T; Miyamoto, N; Pham, LD; Seo, JH | 1 |
| Altenmüller, DM; Feuerstein, TJ; Freiman, TM; Hebel, JM; Rassner, MP; Volz, S; Zentner, J | 1 |
| Bramble, LA; Downing, NJ; Greenwood, KK; Harkema, JR; Lapres, JJ; Proper, SP; Saini, Y | 1 |
| Ichiki, T; Ikeda, J; Inoue, E; Kitamoto, S; Sankoda, C; Sunagawa, K; Takahara, Y; Tokunou, T; Watanabe, A | 1 |
| Dong, S; Le, YZ; Liu, Y; Xu, X; Zhu, M | 1 |
| Alam, HB; Bambakidis, T; Dekker, SE; Halaweish, I; Jin, G; Linzel, D; Liu, B; Maxwell, J; You, Z | 1 |
| Fasching, A; Friederich-Persson, M; Hansell, P; Liss, P; Nangaku, M; Nordquist, L; Palm, F; Shoji, K | 1 |
| Ahn, HY; Choi, M; Joe, YA; Kim, HK; Kim, KS; Lee, HS; Lim, HS; Shin, JC | 1 |
| Li, D; Liu, F; Qi, L; Wang, M; Yan, G; Yang, T | 1 |
| Altenmüller, DM; Feuerstein, TJ; Freiman, TM; Hebel, JM; Herrmann, LS; Rassner, MP; Volz, S | 1 |
| An, S; Feng, M; Huang, J; Li, Z; Liu, L; Qi, J; Shen, H; Zhou, M | 1 |
| Liu, G; Qi, R; Shen, W; Tao, Y; Wang, B; Wang, X; Xu, L | 1 |
| Arai, K; Egawa, N; Ihara, M; Itoh, K; Liang, AC; Lo, EK; Lok, J; Maeda, M; Maki, T; Miyamoto, N; Shindo, A | 1 |
| Assawachananont, J; Eiraku, M; Kimura, T; Kuwahara, A; Mandai, M; Matsushita, K; Nakano, T; Saito, K; Sasai, Y; Shirai, H; Takahashi, M; Terasaki, H; Yonemura, S | 1 |
| Göktalay, G; Millington, WR | 1 |
| Banerjee, T; Holden, JE; Jeong, Y; Wagner, M | 1 |
| Ben Baruch, N; Brakhage, A; Hillmann, F; Iannitti, R; Kniemeyer, O; Osherov, N; Romani, L; Sandovsky-Losica, H; Shadkchan, Y; Vaknin, Y | 1 |
| Chen, L; Liu, J; Liu, P; Wu, X; Xia, K | 1 |
| Fu, W; Gao, X; Hao, X; Ke, X; Ma, N; Wang, W; Wu, J; Zhang, H; Zhang, Z; Zhao, M | 1 |
| Asnacios, A; Chevalier, NR; Dufour, S; Fleury, V; Proux-Gillardeaux, V | 1 |
| Muhammed, H; Suleiman, I; Umar, AH | 1 |
| Dan, T; Miyata, T | 1 |
| Brusco, A; Caltana, L; Lazarowski, A; Merelli, A | 1 |
| Bansal, A; Jain, SK; Khan, YA; Sairam, M; Saxena, S; Shukla, D; Singh, M | 1 |
| Correa, FM; Guimarães, FS; Joca, SR; Lisboa, SF; Scopinho, AA; Scopinho, M | 1 |
| Brusco, A; Caltana, L; Girimonti, P; Lazarowski, A; Merelli, A; Ramos, AJ | 1 |
| Chen, Z; Feng, H; Hu, J; Hu, SL; Li, B; Li, JT; Lin, JK; Qian, ZM; Wei, LJ; Yang, YF; Zhu, G | 1 |
| Liu, F; Liu, YK; Tao, R; Xu, H; Yin, J | 1 |
| Archer, SL; Chen, Y; Fang, YH; Hong, Z; Marsboom, G; Morrow, E; Piao, L; Pogoriler, J; Rehman, J; Ryan, JJ; Thenappan, T; Toth, PT; Weir, EK; Wu, X; Zhang, HJ | 1 |
| Prado, WA; Reis, GM; Rossaneis, AC; Silveira, JW | 1 |
| Ahn, SH; Han, KH; Han, SY; Kim, HS; Lee, YM; Sun, HK | 1 |
| Chan, HH; Fu, ZJ; Fung, FK; Li, SY; Lo, AC; Wong, D | 1 |
| Buczko, W; Koda, M; Pawlak, D; Pawlak, S; Wolczynski, S | 1 |
| Annala, A; Carey, M; Gambhir, SS; Iyer, M; Wang, Y; Wu, L | 1 |
| Noda, T; Shimizu, M; Yamano, T | 1 |
| Li, H; Su, Y; Xiu, R; Zhang, J | 1 |
| Aoki, H; Hara, A; Kozawa, O; Kumada, M; Kunisada, T; Mori, H; Niwa, M; Oyama, T; Yamamoto, T | 1 |
| Brusco, A; Caltana, L; Lazarowski, A; Merelli, A; Ramos, AJ; Rubio, MD | 1 |
| Cerón, SN; Fenoy, FJ; Hernández, I; Lopez, B; Losa, AM; Martínez, JG; Rodriguez, F; Salom, MG | 1 |
| Beart, PM; Callaway, JK; Jones, NM; Kardashyan, L; Lee, EM | 1 |
| de la Iglesia, FA; Dhami, MS; DiFonzo, CJ; Feuer, G; Martin, RA | 1 |
| Mahmood, HA; Marks, V | 1 |
| Färm, G; Lidén, C; Wahlberg, JE | 1 |
| Holstein-Rathlou, NH; Magyar, CE; McDonough, AA; Zhang, YB | 1 |
| Lidén, C; Wahlberg, JE | 1 |
| Feng, GJ; Wu, XR; Zhao, DY; Zuo, QH | 1 |
1 trial(s) available for cobaltous chloride and Disease Models, Animal
63 other study(ies) available for cobaltous chloride and Disease Models, Animal
| Article | Year |
|---|---|
Neuroprotective Effects of a Cardioplegic Combination (Adenosine, Lidocaine, and Magnesium) in an Ischemic Stroke Model.
Topics: Adenosine; Animals; Cardioplegic Solutions; Cobalt; Disease Models, Animal; Glucose; Humans; Ischemic Stroke; Lidocaine; Magnesium; Neuroblastoma; Neuroprotective Agents; Oxygen; Rats; Stroke | 2022 |
Neuroprotective Effects of Transferrin in Experimental Glaucoma Models.
Topics: Animals; Disease Models, Animal; Glaucoma; Hypoxia; Intraocular Pressure; Iron; N-Methylaspartate; Neuroprotective Agents; Ocular Hypertension; Rats; Transferrin | 2022 |
Circadian clock gene Clock is involved in the pathogenesis of preeclampsia through hypoxia.
Topics: Animals; Aorta, Abdominal; Cell Hypoxia; Cell Line; Cell Movement; Cell Proliferation; Circadian Clocks; Cobalt; Disease Models, Animal; Female; Gene Expression Regulation; Gene Silencing; Humans; Hypoxia; Placenta; Pre-Eclampsia; Pregnancy; Rats; RNA, Messenger; Signal Transduction; Transfection; Trophoblasts; Uterine Artery | 2020 |
Chemical hypoxia induces pro-inflammatory signals in fat-laden hepatocytes and contributes to cellular crosstalk with Kupffer cells through extracellular vesicles.
Topics: Animals; Caspase 1; Choline Deficiency; Cobalt; Disease Models, Animal; Extracellular Vesicles; Fatty Acids, Nonesterified; Gene Expression Regulation; Hepatocytes; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammasomes; Inflammation; Interleukin-1beta; Kupffer Cells; Mice; NLR Family, Pyrin Domain-Containing 3 Protein; Non-alcoholic Fatty Liver Disease; Rats; Sleep Apnea, Obstructive; Triglycerides | 2020 |
A circRNA derived from linear HIPK3 relieves the neuronal cell apoptosis in spinal cord injury via ceRNA pattern.
Topics: Adaptor Proteins, Signal Transducing; Animals; Apoptosis; Base Sequence; Blood-Brain Barrier; Cell Line; Cobalt; Disease Models, Animal; Down-Regulation; Humans; Hydrolases; MicroRNAs; Microtubule-Associated Proteins; Nerve Tissue Proteins; Neurons; PC12 Cells; Rats; Rats, Sprague-Dawley; RNA, Circular; Spinal Cord Injuries | 2020 |
Extracellular vesicles derived from fat-laden hepatocytes undergoing chemical hypoxia promote a pro-fibrotic phenotype in hepatic stellate cells.
Topics: Animals; Cell Communication; Cell Hypoxia; Cobalt; Culture Media; Disease Models, Animal; Disease Progression; Extracellular Vesicles; Fatty Acids, Nonesterified; Hep G2 Cells; Hepatic Stellate Cells; Hepatocytes; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Liver Cirrhosis; Male; Mice; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Sleep Apnea, Obstructive | 2020 |
Statin rosuvastatin inhibits apoptosis of human coronary artery endothelial cells through upregulation of the JAK2/STAT3 signaling pathway.
Topics: Animals; Apoptosis; Cell Line; Cobalt; Coronary Vessels; Disease Models, Animal; Endothelial Cells; Gene Expression Regulation; Humans; Male; Myocardial Ischemia; Rats; Reactive Oxygen Species; Rosuvastatin Calcium; Signal Transduction | 2020 |
MicroRNA-203a-3p regulates CoCl
Topics: Animals; Antimutagenic Agents; Apoptosis; Cell Culture Techniques; Cobalt; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Disease Models, Animal; Epithelial Cells; Humans; MicroRNAs; Rats; Retinal Pigment Epithelium; Suppressor of Cytokine Signaling 3 Protein | 2020 |
A Fairy Chemical Suppresses Retinal Angiogenesis as a HIF Inhibitor.
Topics: 3T3 Cells; Angiogenesis Inhibitors; Animals; Cell Hypoxia; Cobalt; Corneal Dystrophies, Hereditary; Disease Models, Animal; Gene Expression Regulation; Hypoxia-Inducible Factor 1; Mice; Retinal Neovascularization; Vascular Endothelial Growth Factor A | 2020 |
Dorsal hippocampus plays a causal role in context-induced reinstatement of alcohol-seeking in rats.
Topics: Alcoholism; Animals; Behavior, Animal; Cobalt; Disease Models, Animal; Extinction, Psychological; Hippocampus; Male; Rats; Rats, Long-Evans; Reinforcement, Psychology | 2021 |
Rice Bran and Vitamin B6 Suppress Pathological Neovascularization in a Murine Model of Age-Related Macular Degeneration as Novel HIF Inhibitors.
Topics: Aged; Animals; Cobalt; Disease Models, Animal; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Infant, Newborn; Macular Degeneration; Mice; Neovascularization, Pathologic; Oryza; Retina; Retinal Pigment Epithelium; Rice Bran Oil; Vascular Endothelial Growth Factor A; Vitamin B 6 | 2020 |
Measurement of In Vitro Single Cell Temperature by Novel Thermocouple Nanoprobe in Acute Lung Injury Models.
Topics: Acute Lung Injury; Adenosine Triphosphate; Animals; Cell Line; Cobalt; Disease Models, Animal; Energy Metabolism; Hydrochloric Acid; Hydrogen Peroxide; Lipopolysaccharides; Lung; Mice; Nanotechnology; Single-Cell Analysis; Temperature; Thermometry | 2017 |
Novel Polysaccharide H-1-2 from Pseudostellaria Heterophylla Alleviates Type 2 Diabetes Mellitus.
Topics: Animals; Blood Glucose; Caryophyllaceae; Cell Line; Cobalt; Diabetes Mellitus, Type 2; Disease Models, Animal; Female; Glucose; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Insulin; Insulin-Secreting Cells; Male; MicroRNAs; Polysaccharides; Promoter Regions, Genetic; Rats; Sirtuin 1; Up-Regulation | 2018 |
Autophagy and Akt in the protective effect of erythropoietin helix B surface peptide against hepatic ischaemia/reperfusion injury in mice.
Topics: Adenine; Animals; Autophagosomes; Autophagy; Cell Line; Chemical and Drug Induced Liver Injury; Chromones; Cobalt; Disease Models, Animal; Erythropoietin; Humans; Liver; Liver Function Tests; Mice; Mice, Inbred C57BL; Morpholines; Peptide Fragments; Proto-Oncogene Proteins c-akt; Random Allocation; Reperfusion Injury; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases | 2018 |
Connexin 43-Mediated Mitochondrial Transfer of iPSC-MSCs Alleviates Asthma Inflammation.
Topics: Animals; Apoptosis; Asthma; Cell Line; Cobalt; Connexin 43; Disease Models, Animal; Epithelial Cells; Humans; Induced Pluripotent Stem Cells; Inflammation; Lung; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mitochondria; Nanotubes; Ovalbumin | 2018 |
Exosomes derived miR-126 attenuates oxidative stress and apoptosis from ischemia and reperfusion injury by targeting ERRFI1.
Topics: Adaptor Proteins, Signal Transducing; Animals; Apoptosis; Cell Survival; Cobalt; Disease Models, Animal; Exosomes; HEK293 Cells; Humans; Hydrogen Peroxide; Intracellular Signaling Peptides and Proteins; Male; Membrane Potential, Mitochondrial; MicroRNAs; Myocardial Reperfusion Injury; Oxidative Stress; Rats; Tumor Suppressor Proteins | 2019 |
Hyperbaric oxygen preconditioning attenuates hyperglycemia-enhanced hemorrhagic transformation by inhibiting matrix metalloproteinases in focal cerebral ischemia in rats.
Topics: Analysis of Variance; Animals; Blood Glucose; Cerebral Hemorrhage; Cerebral Infarction; Cobalt; Disease Models, Animal; Free Radical Scavengers; Gene Expression Regulation; Glucose; Hemoglobins; Hyperbaric Oxygenation; Hyperglycemia; Infarction, Middle Cerebral Artery; Ischemic Preconditioning; Male; Metalloproteases; Neurologic Examination; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Spectrophotometry; Time Factors | 2013 |
Age-related decline in oligodendrogenesis retards white matter repair in mice.
Topics: Aging; Animals; Antimutagenic Agents; Cells, Cultured; Cobalt; Cognition Disorders; Corpus Callosum; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Hypoxia, Brain; Leukoencephalopathies; Male; Mice; Mice, Inbred C57BL; Myelin Sheath; Neural Stem Cells; Neurogenesis; Neuroprotective Agents | 2013 |
Locally applied valproate enhances survival in rats after neocortical treatment with tetanus toxin and cobalt chloride.
Topics: Animals; Anticonvulsants; Behavior, Animal; Cobalt; Disease Models, Animal; Electroencephalography; Epilepsy; Rats; Rats, Sprague-Dawley; Tetanus Toxin; Valproic Acid | 2013 |
Loss of hypoxia-inducible factor 2 alpha in the lung alveolar epithelium of mice leads to enhanced eosinophilic inflammation in cobalt-induced lung injury.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Bronchoalveolar Lavage Fluid; Cobalt; Cytokines; Disease Models, Animal; Doxycycline; Gene Expression Profiling; Immunohistochemistry; Lung Injury; Mice; Mice, Knockout; Pulmonary Alveoli; Pulmonary Eosinophilia; Respiratory Mucosa | 2014 |
Suppression of abdominal aortic aneurysm formation by inhibition of prolyl hydroxylase domain protein through attenuation of inflammation and extracellular matrix disruption.
Topics: Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortitis; Calcium Chloride; Catalase; Cobalt; Cytokines; Disease Models, Animal; Enzyme Inhibitors; Extracellular Matrix; Hypoxia-Inducible Factor-Proline Dioxygenases; Inflammation Mediators; Macrophages; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Phosphorylation; Superoxide Dismutase; Superoxide Dismutase-1; Time Factors; Transcription Factor RelA | 2014 |
Simplified system to investigate alteration of retinal neurons in diabetes.
Topics: Animals; Antimutagenic Agents; Biomarkers; Cobalt; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Disease Models, Animal; Hypoxia; Mice; Mice, Inbred C57BL; Retina; Retinal Neurons | 2014 |
Development of a novel neuroprotective strategy: combined treatment with hypothermia and valproic acid improves survival in hypoxic hippocampal cells.
Topics: Acetylation; Animals; beta Catenin; Cell Hypoxia; Cell Line; Cell Survival; Cobalt; Combined Modality Therapy; Disease Models, Animal; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; Histone Deacetylase Inhibitors; Histones; HMGB1 Protein; Hypothermia, Induced; Hypoxia-Inducible Factor 1, alpha Subunit; Hypoxia, Brain; Mice; Neuroprotective Agents; Phosphorylation; Valproic Acid | 2014 |
Activation of hypoxia-inducible factors prevents diabetic nephropathy.
Topics: Animals; Antioxidants; Cobalt; Cyclic N-Oxides; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Glomerular Filtration Rate; Hypoxia-Inducible Factor 1; Kidney; Male; Oxidative Stress; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Spin Labels | 2015 |
Priming Wharton's jelly-derived mesenchymal stromal/stem cells with ROCK inhibitor improves recovery in an intracerebral hemorrhage model.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blotting, Western; Cell Differentiation; Cells, Cultured; Cerebral Hemorrhage; Cobalt; Disease Models, Animal; Gene Expression; Glial Cell Line-Derived Neurotrophic Factor; Humans; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Microscopy, Confocal; Neurons; Protein Kinase Inhibitors; Rats, Sprague-Dawley; Recovery of Function; Reverse Transcriptase Polymerase Chain Reaction; rho-Associated Kinases; Wharton Jelly | 2015 |
Regulation on Beclin-1 expression by mTOR in CoCl2-induced HT22 cell ischemia-reperfusion injury.
Topics: Analysis of Variance; Animals; Antimutagenic Agents; Apoptosis Regulatory Proteins; Beclin-1; Brain Ischemia; Cell Line; Cell Survival; Cobalt; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Male; Mice; Neurons; Phosphorylation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sirolimus | 2015 |
Reduction of epileptiform activity through local valproate-implants in a rat neocortical epilepsy model.
Topics: Animals; Anticonvulsants; Cobalt; Disease Models, Animal; Drug Implants; Electrocorticography; Electromyography; Epilepsy; Motor Cortex; Polymers; Rats, Sprague-Dawley; Seizures; Temporal Muscle; Tetanus Toxin; Valproic Acid; Video Recording | 2015 |
Effect of CoCl₂ on fracture repair in a rat model of bone fracture.
Topics: Animals; Biomechanical Phenomena; Bone Remodeling; Cobalt; Disease Models, Animal; Fracture Healing; Fractures, Bone; Hypoxia; Hypoxia-Inducible Factor 1; Immunohistochemistry; Osteogenesis; Rats | 2015 |
Efficient siRNA Delivery Using PEG-conjugated PAMAM Dendrimers Targeting Vascular Endothelial Growth Factor in a CoCl2-induced Neovascularization Model in Retinal Endothelial Cells.
Topics: Animals; Cells, Cultured; Cobalt; Dendrimers; Disease Models, Animal; Macaca; Neovascularization, Pathologic; Polyethylene Glycols; Retinal Vessels; RNA, Small Interfering; Vascular Endothelial Growth Factor A | 2016 |
Astrocytes Promote Oligodendrogenesis after White Matter Damage via Brain-Derived Neurotrophic Factor.
Topics: Animals; Antimutagenic Agents; Astrocytes; Brain Ischemia; Brain-Derived Neurotrophic Factor; Cell Differentiation; Cells, Cultured; Chromones; Cobalt; Culture Media, Conditioned; Disease Models, Animal; Enzyme Inhibitors; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Glutathione S-Transferase pi; Hypoxia-Inducible Factor 1, alpha Subunit; Leukoencephalopathies; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Morpholines; Myelin Basic Protein; Myelin Sheath; Phosphopyruvate Hydratase; Stem Cells | 2015 |
Transplantation of human embryonic stem cell-derived retinal tissue in two primate models of retinal degeneration.
Topics: Animals; Cell Differentiation; Cobalt; Disease Models, Animal; Haplorhini; Human Embryonic Stem Cells; Humans; Photoreceptor Cells; Primates; Rats; Retina; Retinal Degeneration | 2016 |
Hypovolemic hemorrhage induces Fos expression in the rat hypothalamus: Evidence for involvement of the lateral hypothalamus in the decompensatory phase of hemorrhage.
Topics: Animals; Bradycardia; Cobalt; Disease Models, Animal; Hemorrhage; Hemostatics; Hypothalamus; Hypovolemia; Lidocaine; Male; Neurons; Proto-Oncogene Proteins c-fos; Rats, Sprague-Dawley | 2016 |
Sex differences in hypothalamic-mediated tonic norepinephrine release for thermal hyperalgesia in rats.
Topics: Adrenergic alpha-Antagonists; Animals; Cobalt; Constriction, Pathologic; Dioxanes; Disease Models, Animal; Female; Hot Temperature; Hyperalgesia; Hypothalamus; Male; Neuralgia; Nociceptive Pain; Norepinephrine; Random Allocation; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Sciatic Nerve; Sex Characteristics; Yohimbine | 2016 |
Identification and Characterization of a Novel Aspergillus fumigatus Rhomboid Family Putative Protease, RbdA, Involved in Hypoxia Sensing and Virulence.
Topics: Animals; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Cobalt; Disease Models, Animal; Female; Fungal Proteins; Gene Expression Regulation, Fungal; Host-Pathogen Interactions; Hypoxia; Immunocompromised Host; Larva; Lung; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Moths; Mutation; Neurospora crassa; Peptide Hydrolases; Signal Transduction; Spores, Fungal; Sterol Regulatory Element Binding Proteins; Ubiquitin-Protein Ligases; Virulence | 2016 |
Effect of leptin combined with CoCl2 on healing in Sprague Dawley Rat fracture model.
Topics: Animals; Cobalt; Core Binding Factor Alpha 1 Subunit; Disease Models, Animal; Drug Therapy, Combination; Femoral Fractures; Fracture Healing; Hypoxia-Inducible Factor 1, alpha Subunit; Injections, Intraperitoneal; Leptin; Male; Random Allocation; Rats; Rats, Sprague-Dawley; Treatment Outcome; Up-Regulation; Vascular Endothelial Growth Factor A | 2016 |
Inhibition of Hypoxia-Induced Retinal Angiogenesis by Specnuezhenide, an Effective Constituent of Ligustrum lucidum Ait., through Suppression of the HIF-1α/VEGF Signaling Pathway.
Topics: Angiogenesis Inhibitors; Animals; Cell Hypoxia; Cell Line; Cobalt; Diabetic Retinopathy; Disease Models, Animal; Epithelial Cells; Gene Expression Regulation; Glucosides; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Hypoxia-Inducible Factor-Proline Dioxygenases; Indazoles; Ligustrum; Plant Extracts; Pyrans; Rats; Rats, Sprague-Dawley; Retinal Neovascularization; Retinal Pigment Epithelium; Signal Transduction; Vascular Endothelial Growth Factor A | 2016 |
Emergence and development of gut motility in the chicken embryo.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Movement; Chick Embryo; Cobalt; Disease Models, Animal; Hirschsprung Disease; Intestines; Muscle, Smooth; Myenteric Plexus; Neural Crest; Organ Culture Techniques; Peristalsis; Tetrodotoxin; Time-Lapse Imaging | 2017 |
Effect of Low Dose Lead (Pb) Administration on Tail Immersion Test and Formalin-induced Pain in Wistar Rats: Possible Modulatory Role of Cobalt (II) Chloride.
Topics: Animals; Behavior, Animal; Cobalt; Disease Models, Animal; Female; Formaldehyde; Male; Organometallic Compounds; Pain; Pain Perception; Rats, Wistar; Reaction Time; Time Factors | 2017 |
Inhibition of advanced glycation end products (AGEs): an implicit goal in clinical medicine for the treatment of diabetic nephropathy?
Topics: Animals; Caloric Restriction; Cobalt; Diabetic Nephropathies; Disease Models, Animal; Glycation End Products, Advanced; Hypoglycemic Agents; Hypoxia-Inducible Factor 1, alpha Subunit; Oxidative Stress; Rats; Treatment Outcome | 2008 |
Neuronal and glial alterations due to focal cortical hypoxia induced by direct cobalt chloride (CoCl2) brain injection.
Topics: Analysis of Variance; Animals; Antimutagenic Agents; Brain; Cell Death; Cobalt; Disease Models, Animal; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; In Situ Nick-End Labeling; Lectins; Male; Microscopy, Electron, Transmission; Nerve Tissue Proteins; Neuroglia; Neurons; Rats; Rats, Wistar; Staining and Labeling; Time Factors | 2009 |
Hypoxia preconditioning by cobalt chloride enhances endurance performance and protects skeletal muscles from exercise-induced oxidative damage in rats.
Topics: Animals; Antioxidants; Cell Hypoxia; Cobalt; Creatine Kinase, MM Form; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Glutathione; Heme Oxygenase (Decyclizing); Lactic Acid; Lipid Peroxidation; Lipofuscin; Male; Metallothionein; Mitochondria, Muscle; Mitochondrial Proteins; Muscle, Skeletal; Muscular Diseases; Necrosis; Oxidative Stress; Physical Endurance; Physical Exertion; Rats; Rats, Wistar; Reactive Oxygen Species | 2010 |
Acute reversible inactivation of the ventral medial prefrontal cortex induces antidepressant-like effects in rats.
Topics: Animals; Antidepressive Agents; Cobalt; Depression; Disease Models, Animal; Male; Microinjections; Motor Activity; Prefrontal Cortex; Rats; Rats, Wistar; Swimming; Synaptic Transmission | 2010 |
Recovery of motor spontaneous activity after intranasal delivery of human recombinant erythropoietin in a focal brain hypoxia model induced by CoCl2 in rats.
Topics: Administration, Intranasal; Analysis of Variance; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cobalt; Disease Models, Animal; Erythropoietin; Exploratory Behavior; Gene Expression Regulation; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Hypoxia, Brain; Male; Motor Activity; Rats; Rats, Wistar; Receptors, Erythropoietin; Recombinant Proteins; Recovery of Function; Reticulocytes; Rotarod Performance Test | 2011 |
Interleukin-1 receptor associated kinases-1/4 inhibition protects against acute hypoxia/ischemia-induced neuronal injury in vivo and in vitro.
Topics: Animals; Apoptosis; Brain Infarction; Caspase 3; Cells, Cultured; Cerebral Cortex; Cobalt; Disease Models, Animal; Enzyme Inhibitors; Humans; Hypoxia-Ischemia, Brain; Infarction, Middle Cerebral Artery; Interleukin-1 Receptor-Associated Kinases; Interleukin-6; JNK Mitogen-Activated Protein Kinases; Male; Neurons; Neuroprotective Agents; NF-kappa B; Rats; Rats, Sprague-Dawley; Signal Transduction; Tumor Necrosis Factor-alpha | 2011 |
Effects of serum cobalt ion concentration on the liver, kidney and heart in mice.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cobalt; Disease Models, Animal; Dose-Response Relationship, Drug; Heart Diseases; Hepatocytes; Joint Prosthesis; Kidney; Kidney Diseases; Male; Mice; Mice, Inbred ICR; Microscopy, Electron; Myocytes, Cardiac | 2010 |
Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension.
Topics: Animals; Antihypertensive Agents; Case-Control Studies; CDC2 Protein Kinase; Cell Cycle Checkpoints; Cell Proliferation; Cells, Cultured; Cobalt; Cyclin B1; Disease Models, Animal; Dynamins; Enzyme Activation; Familial Primary Pulmonary Hypertension; Genetic Therapy; Glycolysis; GTP Phosphohydrolases; Humans; Hypertension, Pulmonary; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Microtubule-Associated Proteins; Mitochondria, Muscle; Mitochondrial Proteins; Mitosis; Monocrotaline; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Pulmonary Artery; Quinazolinones; Rats; Rats, Sprague-Dawley; RNA Interference; Serine; Time Factors; Transfection | 2012 |
μ1- and 5-HT1-dependent mechanisms in the anterior pretectal nucleus mediate the antinociceptive effects of retrosplenial cortex stimulation in rats.
Topics: Animals; Atropine; Cerebral Cortex; Cobalt; Disease Models, Animal; Electric Stimulation Therapy; Male; Methiothepin; Naloxone; Pain Management; Pain Threshold; Rats; Rats, Wistar; Receptors, Opioid, mu; Receptors, Serotonin, 5-HT1 | 2012 |
Phosphodiesterase inhibitor improves renal tubulointerstitial hypoxia of the diabetic rat kidney.
Topics: Animals; Cell Line; Cobalt; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Gene Expression Regulation; Glucose; Glucose Transporter Type 1; Heme Oxygenase (Decyclizing); Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Kidney Tubules; Male; Pentoxifylline; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Streptozocin; Time Factors; Vascular Endothelial Growth Factor A | 2012 |
Anti-inflammatory effects of lutein in retinal ischemic/hypoxic injury: in vivo and in vitro studies.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Cells, Cultured; Cobalt; Cyclooxygenase 2; Disease Models, Animal; Electroretinography; Glial Fibrillary Acidic Protein; Hypoxia; Interleukin-1beta; Lutein; Male; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neuroglia; NF-kappa B; Photic Stimulation; Rats; Reperfusion Injury; Retina; Retinal Diseases; Tumor Necrosis Factor-alpha | 2012 |
Contribution of quinolinic acid in the development of anemia in renal insufficiency.
Topics: Anemia; Animals; Carcinoma, Hepatocellular; Cell Hypoxia; Cell Survival; Cobalt; Disease Models, Animal; Dose-Response Relationship, Drug; Erythropoiesis; Erythropoietin; Humans; Kidney Failure, Chronic; Male; Neurotoxins; Organ Specificity; Quinolinic Acid; Rats; Rats, Wistar; RNA, Messenger; Tumor Cells, Cultured | 2003 |
Noninvasive indirect imaging of vascular endothelial growth factor gene expression using bioluminescence imaging in living transgenic mice.
Topics: Animals; Cell Hypoxia; Cobalt; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation; HeLa Cells; Humans; Luciferases, Firefly; Luminescence; Mice; Mice, Transgenic; Transcription, Genetic; Transcriptional Activation; Up-Regulation; Vascular Endothelial Growth Factor A; Whole Body Imaging; Wound Healing | 2006 |
Allergenicity and cross-reactivity of naphthenic acid and its metallic salts in experimental animals.
Topics: Allergens; Animals; Carboxylic Acids; Chlorides; Cobalt; Cross Reactions; Dermatitis, Allergic Contact; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Guinea Pigs; Mice; Mice, Inbred BALB C; Patch Tests; Zinc Compounds | 2006 |
Down-regulation of hepatocyte growth factor mRNA in rat cardiac myocytes under hypoxia mimicked by cobalt chloride.
Topics: Animals; Cells, Cultured; Cobalt; Disease Models, Animal; Down-Regulation; Hepatocyte Growth Factor; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2006 |
A new model of retinal photoreceptor cell degeneration induced by a chemical hypoxia-mimicking agent, cobalt chloride.
Topics: Animals; Cell Death; Cobalt; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; In Situ Nick-End Labeling; Male; Mice; Photoreceptor Cells; Retinal Degeneration; Time Factors | 2006 |
Neuronal mdr-1 gene expression after experimental focal hypoxia: a new obstacle for neuroprotection?
Topics: Animals; Antimutagenic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cobalt; Disease Models, Animal; Gene Expression; Glial Fibrillary Acidic Protein; Hypoxia; Male; Microscopy, Electron, Transmission; Neurons; Parietal Lobe; Phosphopyruvate Hydratase; Rats; Rats, Wistar | 2007 |
Heme oxygenase-1 induction improves ischemic renal failure: role of nitric oxide and peroxynitrite.
Topics: Acute Kidney Injury; Animals; Cobalt; Disease Models, Animal; Enzyme Induction; Enzyme Inhibitors; Glomerular Filtration Rate; Heme Oxygenase (Decyclizing); Ischemia; Isoenzymes; Kidney Medulla; Male; Metalloporphyrins; Nitric Oxide; Nitric Oxide Synthase; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Renal Circulation; Reperfusion Injury; Sulfhydryl Compounds; Time Factors | 2007 |
Long-term functional and protective actions of preconditioning with hypoxia, cobalt chloride, and desferrioxamine against hypoxic-ischemic injury in neonatal rats.
Topics: Animals; Animals, Newborn; Behavior, Animal; Brain; Cobalt; Deferoxamine; Disease Models, Animal; Female; Hypoxia; Hypoxia-Ischemia, Brain; Male; Motor Skills; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Time Factors | 2008 |
Functional responses of the rat hepatic endoplasmic reticulum to treatment proposed as a model for cholestasis.
Topics: Animals; Aspartate Aminotransferases; Bilirubin; Cholestasis; Cobalt; Disease Models, Animal; Endoplasmic Reticulum; Hypertrophy; Lipoproteins; Liver; Male; Microsomes, Liver; Rats; Rats, Inbred Strains; Triglycerides | 1983 |
The hypertriglyceridaemia of the cobalt chloride-treated rat: a possible mechanism.
Topics: Animals; Cholesterol; Cobalt; Disease Models, Animal; Fatty Acids, Nonesterified; Hyperlipoproteinemia Type IV; Lipids; Lipoprotein Lipase; Liver; Male; Organ Size; Rats; Triglycerides | 1981 |
Quantification and specificity of the repeated open application test (ROAT). A methodological study using cobalt and colophony in guinea pigs.
Topics: Animals; Antimutagenic Agents; Cobalt; Dermatitis, Allergic Contact; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Patch Tests; Reference Values; Resins, Plant; Sensitivity and Specificity; Tars | 1997 |
The cytochrome P-450 inhibitor cobalt chloride prevents inhibition of renal Na,K-ATPase and redistribution of apical NHE-3 during acute hypertension.
Topics: Acute Disease; Analysis of Variance; Animals; Cobalt; Culture Techniques; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Disease Models, Animal; Hypertension; Immunoblotting; Kidney Cortex; Lithium; Male; Rats; Rats, Sprague-Dawley; Reference Values; Renal Circulation; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase; Urine | 1998 |
Cross-reactivity patterns of cobalt and nickel studied with repeated open applications (ROATS) to the skin of guinea pigs.
Topics: Animals; Cobalt; Cross Reactions; Dermatitis, Allergic Contact; Disease Models, Animal; Female; Guinea Pigs; Irritants; Nickel; Patch Tests; Sensitivity and Specificity | 2000 |
Seizures induced by intraventricular microinjection of ionized cobalt in the rat--a new experimental model of epilepsy.
Topics: Animals; Anticonvulsants; Cobalt; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Injections, Intraventricular; Microinjections; Rats; Rats, Inbred Strains; Seizures | 1985 |