cobaltous chloride has been researched along with Breast Cancer in 35 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (2.86) | 18.2507 |
2000's | 15 (42.86) | 29.6817 |
2010's | 15 (42.86) | 24.3611 |
2020's | 4 (11.43) | 2.80 |
Authors | Studies |
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Antony, GR; Littleflower, AB; Parambil, ST; Subhadradevi, L | 1 |
Kingham, PJ; Lauvrud, AT; Nyström, M; Pérez-Díaz, S; Wiberg, R | 1 |
Ali, M; Chang, HY; Chen, HY; Chiang, YF; Hsia, SM; Huang, KC; Huang, TC; Lin, CE; Shieh, TM; Wang, KL; Wu, SC; Yang, ZY | 1 |
Barrak, NH; Khajah, MA; Luqmani, YA | 1 |
Aasbrenn, M; Abd El-Aty, AM; Abdu, A; Abraha, HB; Achour, A; Acquaroni, M; Addeo, P; Agback, P; Agback, T; Al-Alwan, M; Al-Mazrou, A; Al-Mohanna, F; Aliste, M; Almquist, J; Andel, J; Ando, M; Angelov, A; Annuar, MSM; Antwi, K; Arroliga, AC; Arruda, SLM; Asch, SM; Averous, G; Ayaz, S; Ayer, GB; Bachellier, P; Ball, S; Banijamali, AR; Barden, TC; Bartoncini, S; Bedanie, G; Bellò, M; Benić, F; Berhe, GG; Bertiger, G; Beumer, JH; Bhandari, B; Bond, DS; Boules, M; Braüner Christensen, J; Brown-Johnson, C; Burgstaller, S; Cao, L; Capasso, C; Carlevato, R; Carvalho, AE; Ceci, F; Chagas, ATA; Chavan, SG; Chen, AP; Chen, HC; Chen, J; Chen, Q; Chen, Y; Chen, YF; Christ, ER; Chu, CW; Covey, JM; Coyne, GO'; Cristea, MC; Currie, MG; Dahdal, DN; Dai, L; Dang, Z; de Abreu, NL; de Carvalho, KMB; de la Plaza Llamas, R; Deandreis, D; Del Prete, S; Dennis, JA; Deur, J; Díaz Candelas, DA; Divyapriya, G; Djanani, A; Dodig, D; Doki, Y; Doroshow, JH; Dos Santos, RC; Durairaj, N; Dutra, ES; Eguchi, H; Eisterer, W; Ekmann, A; Elakkad, A; Evans, WE; Fan, W; Fang, Z; Faria, HP; Farris, SG; Fenoll, J; Fernandez-Botran, R; Flores, P; Fujita, J; Gan, L; Gandara, DR; Gao, X; Garcia, AA; Garrido, I; Gebru, HA; Gerger, A; Germano, P; Ghamande, S; Ghebeh, H; Giver Jensen, T; Go, A; Goichot, B; Goldwater, M; Gontero, P; Greil, R; Gruenberger, B; Guarneri, A; Guo, Y; Gupta, S; Haxholdt Lunn, T; Hayek, AJ; He, ML; Hellín, P; Hepprich, M; Hernández de Rodas, E; Hill, A; Hndeya, AG; Holdsworth, LM; Hookey, L; Howie, W; Hu, G; Huang, JD; Huang, SY; Hubmann, E; Hwang, SY; Imamura, H; Imperiale, A; Jiang, JQ; Jimenez, JL; Jin, F; Jin, H; Johnson, KL; Joseph, A; Juwara, L; Kalapothakis, E; Karami, H; Karayağiz Muslu, G; Kawabata, R; Kerwin, J; Khan, I; Khin, S; Kidanemariam, HG; Kinders, RJ; Klepov, VV; Koehler, S; Korger, M; Kovačić, S; Koyappayil, A; Kroll, MH; Kuban, J; Kummar, S; Kung, HF; Kurokawa, Y; Laengle, F; Lan, J; Leal, HG; Lee, MH; Lemos, KGE; Li, B; Li, G; Li, H; Li, X; Li, Y; Li, Z; Liebl, W; Lillaz, B; Lin, F; Lin, L; Lin, MCM; Lin, Y; Lin, YP; Lipton, RB; Liu, J; Liu, W; Liu, Z; Lu, J; Lu, LY; Lu, YJ; Ludwig, S; Luo, Y; Ma, L; Ma, W; Machado-Coelho, GLL; Mahmoodi, B; Mahoney, M; Mahvash, A; Mansour, FA; Mao, X; Marinho, CC; Masferrer, JL; Matana Kaštelan, Z; Melendez-Araújo, MS; Méndez-Chacón, E; Miletić, D; Miller, B; Miller, E; Miller, SB; Mo, L; Moazzen, M; Mohammadniaei, M; Montaz-Rosset, MS; Mousavi Khaneghah, A; Mühlethaler, K; Mukhopadhyay, S; Mulugeta, A; Nambi, IM; Navarro, S; Nazmara, S; Neumann, HJ; Newman, EM; Nguyen, HTT; Nicolato, AJPG; Nicolotti, DG; Nieva, JJ; Nilvebrant, J; Nocentini, A; Nugent, K; Nunez-Rodriguez, DL; Nygren, PÅ; Oberli, A; Oderda, M; Odisio, B; Oehler, L; Otludil, B; Overman, M; Özdemir, M; Pace, KA; Palm, H; Parchment, RE; Parise, R; Passera, R; Pavlovic, J; Pecherstorfer, M; Peng, Z; Pérez Coll, C; Petzer, A; Philipp-Abbrederis, K; Pichler, P; Piekarz, RL; Pilati, E; Pimentel, JDSM; Posch, F; Prager, G; Pressel, E; Profy, AT; Qi, P; Qi, Y; Qiu, C; Rajasekhar, B; Ramia, JM; Raynor, HA; Reis, VW; Reubi, JC; Ricardi, U; Riedl, JM; Romano, F; Rong, X; Rubinstein, L; Rumboldt, Z; Sabir, S; Safaeinili, N; Sala, BM; Sandoval Castillo, L; Sau, M; Sbhatu, DB; Schulte, T; Scott, V; Shan, H; Shao, Y; Shariatifar, N; Shaw, JG; She, Y; Shen, B; Shernyukov, A; Sheth, RA; Shi, B; Shi, R; Shum, KT; Silva, JC; Singh, A; Sinha, N; Sirajudeen, AAO; Slaven, J; Sliwa, T; Somme, F; Song, S; Steinberg, SM; Subramaniam, R; Suetta, C; Sui, Y; Sun, B; Sun, C; Sun, H; Sun, Y; Supuran, CT; Surger, M; Svartz, G; Takahashi, T; Takeno, A; Tam, AL; Tang, Z; Tanner, JA; Tannich, E; Taye, MG; Tekle, HT; Thomas, GJ; Tian, Y; Tobin, JV; Todd Milne, G; Tong, X; Une, C; Vela, N; Venkateshwaran, U; Villagrán de Tercero, CI; Wakefield, JD; Wampfler, R; Wan, M; Wang, C; Wang, J; Wang, L; Wang, S; Waser, B; Watt, RM; Wei, B; Wei, L; Weldemichael, MY; Wellmann, IA; Wen, A; Wild, D; Wilthoner, K; Winder, T; Wing, RR; Winget, M; Wöll, E; Wong, KL; Wong, KT; Wu, D; Wu, Q; Wu, Y; Xiang, T; Xiang, Z; Xu, F; Xu, L; Yamasaki, M; Yamashita, K; Yan, H; Yan, Y; Yang, C; Yang, H; Yang, J; Yang, N; Yang, Y; Yau, P; Yu, M; Yuan, Q; Zhan, S; Zhang, B; Zhang, H; Zhang, J; Zhang, N; Zhang, Y; Zhao, X; Zheng, BJ; Zheng, H; Zheng, W; Zhou, H; Zhou, X; Zhu, S; Zimmer, DP; Zionts, D; Zitella, A; Zlott, J; Zolfaghari, K; Zuo, D; Zur Loye, HC; Žuža, I | 1 |
Buadze, T; Gaiozishvili, M; Jokhadze, T; Lezhava, T; Namchelvadze, E; Sigua, T | 1 |
Abrigo, M; Bal de Kier Joffé, ED; Berardi, DE; Fiszman, GL; Rodríguez, CE; Todaro, LB | 1 |
Barral-Cagiao, L; Costoya, JA; Iglesias, P; Pazos, E; Penas, C | 1 |
Fei, F; Li, L; Luo, L; Qu, Y; Rong, Z | 1 |
Alayoubi, AY; Ananthula, S; Behery, FA; El Sayed, K; Nazzal, S; Parajuli, P; Sylvester, PW | 1 |
Choi, HS; Go, H; Jang, BH; Ko, SG; Ku, JM; Seo, HS; Shin, YC; Woo, JK | 1 |
Chen, H; Hu, L; Li, D; Li, Z; Wu, Z; Zhu, Q | 1 |
Dang, X; Li, S; Liu, Y; Wu, C; Yang, H; Zhang, J | 1 |
Chu, CY; Jin, YT; Liu, XP; Wang, HY; Yang, HP; Yu, J; Zhang, W; Zhang, ZJ; Zou, Q | 1 |
Fei, F; Wang, S; Wang, X; Wu, Q; Wu, Z; Yang, Z; Zhang, D; Zhang, S | 1 |
Cheon, CI; Jung, S; Kim, KI; Lee, MS; Li, C; Lim, JS; Yang, Y | 1 |
Pu, HH; Shi, L; Zhang, QY; Zhao, CB | 1 |
Depping, R; Dunst, J; Jelkmann, W; Kosyna, FK; Wolff, M | 1 |
Botlagunta, M; Kluth, JB; Krishnamachary, B; Mukadam, S; Raman, V; Vesuna, F; Winnard, PT | 1 |
Fu, OY; Hou, MF; Huang, SC; Lee, WY; Yang, SF | 1 |
Amodeo, V; Bazan, V; Cascio, S; D'Andrea, A; Ferla, R; Gebbia, N; Gulotta, E; Russo, A; Surmacz, E | 1 |
Chen, CL; Chu, JS; Huang, SC; Lee, WY; Su, WC | 1 |
Burghardt, R; Dean, D; Safe, S; Saville, B; Stoner, M; Wormke, M | 1 |
Coradini, D; Daidone, MG; Pellizzaro, C; Speranza, A | 1 |
Abcouwer, SF; Bobrovnikova-Marjon, EV; Marjon, PL | 1 |
Cho, J; Kim, D; Lee, S; Lee, Y | 1 |
Böcker, W; Buerger, H; Götte, M; Greb, R; Kersting, C; Kiesel, L; Schmidt, H; Sonntag, B; Wülfing, C; Wülfing, P | 1 |
Fischgräbe, J; Götte, M; Kersting, C; Kiesel, L; Smollich, M; Wülfing, P | 1 |
Koga, F; Neckers, LM; Tsutsumi, S | 1 |
Khan, S; Liu, S; Safe, S; Stoner, M | 1 |
Auriemma, A; Bartella, V; Cascio, S; Giordano, A; Johannes, GJ; Russo, A; Surmacz, E | 1 |
Gonias, SL; Jo, M; Lester, RD; Montel, V; Takimoto, S | 1 |
Campana, WM; Gaultier, A; Gonias, SL; Lester, RD; Montel, V | 1 |
An, WG; Blagosklonny, MV; Costa, M; Melillo, G; Salnikow, K | 1 |
Chandel, NS; Schumacker, PT; Thompson, CB; Vander Heiden, MG | 1 |
1 trial(s) available for cobaltous chloride and Breast Cancer
34 other study(ies) available for cobaltous chloride and Breast Cancer
Article | Year |
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Metabolic Phenotype Intricacies on Altered Glucose Metabolism of Breast Cancer Cells upon Glut-1 Inhibition and Mimic Hypoxia In Vitro.
Topics: Breast Neoplasms; Cell Line, Tumor; Female; Glucose; Glycolysis; Humans; Hypoxia; Phenotype | 2023 |
Interaction of adipose-derived stem cells with active and dormant breast cancer cells.
Topics: Adipose Tissue; Breast Neoplasms; Cell Proliferation; Culture Media, Conditioned; Female; Humans; Stem Cells; Tenascin | 2023 |
Para-toluenesulfonamide, a novel potent carbonic anhydrase inhibitor, improves hypoxia-induced metastatic breast cancer cell viability and prevents resistance to αPD-1 therapy in triple-negative breast cancer.
Topics: Animals; Antigens, Neoplasm; Breast Neoplasms; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Female; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; p38 Mitogen-Activated Protein Kinases; Triple Negative Breast Neoplasms; Vascular Endothelial Growth Factor A | 2023 |
Hypoxic environment may enhance migration/penetration of endocrine resistant MCF7- derived breast cancer cells through monolayers of other non-invasive cancer cells in vitro.
Topics: Basement Membrane; Breast Neoplasms; Cell Hypoxia; Cell Line, Tumor; Cell Movement; Cobalt; Coculture Techniques; Deferoxamine; Epithelial-Mesenchymal Transition; Estrogens; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; MCF-7 Cells; Neoplasm Invasiveness; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Receptors, Estrogen; RNA, Small Interfering; Sepharose | 2020 |
[EVALUATION OF GENOMIC PARAMETERS IN DUCTAL BREAST CANCER PATIENTS AND THE ABILITY OF IT'S CORRECTION].
Topics: Breast Neoplasms; Carcinoma, Ductal, Breast; Cells, Cultured; Chromosome Aberrations; Cobalt; DNA Breaks, Single-Stranded; Female; Humans; Lymphocytes; Oligopeptides; Sister Chromatid Exchange | 2017 |
Breast cancer stem cells are involved in Trastuzumab resistance through the HER2 modulation in 3D culture.
Topics: Breast Neoplasms; Cell Culture Techniques; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Cobalt; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Neoplastic Stem Cells; Receptor, ErbB-2; Spheroids, Cellular; Trastuzumab | 2018 |
A Bio-inspired Hypoxia Sensor using HIF1a-Oxygen-Dependent Degradation Domain.
Topics: Animals; Biosensing Techniques; Breast Neoplasms; Cell Hypoxia; Cell Line, Tumor; Cobalt; Female; Fluorescent Dyes; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Leupeptins; Mice; Mice, Inbred BALB C; Mice, Nude; Mimosine; Oxygen; Peptides; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Domains; Proteolysis; Spectrometry, Fluorescence | 2019 |
Combined treatment of glibenclamide and CoCl2 decreases MMP9 expression and inhibits growth in highly metastatic breast cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cobalt; Female; Gene Expression Regulation, Neoplastic; Glyburide; Humans; Matrix Metalloproteinase 9; Mice; Neoplasm Metastasis; Proliferating Cell Nuclear Antigen; RNA, Messenger; Tumor Burden | 2013 |
δ-Tocotrienol oxazine derivative antagonizes mammary tumor cell compensatory response to CoCl2-induced hypoxia.
Topics: Animals; Breast Neoplasms; Cell Hypoxia; Cell Line, Tumor; Cobalt; Female; Gene Expression Regulation, Neoplastic; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Mammary Neoplasms, Animal; Mice; Signal Transduction; Vitamin E | 2014 |
Apigenin induces caspase-dependent apoptosis by inhibiting signal transducer and activator of transcription 3 signaling in HER2-overexpressing SKBR3 breast cancer cells.
Topics: Apigenin; Apoptosis; Breast Neoplasms; Caspase 3; Caspase 8; Caspases; Cell Line, Tumor; Cell Proliferation; Cobalt; Enzyme-Linked Immunosorbent Assay; Female; G1 Phase Cell Cycle Checkpoints; Humans; Immunohistochemistry; Janus Kinase 2; Phosphorylation; Poly(ADP-ribose) Polymerases; Receptor, ErbB-2; Signal Transduction; STAT3 Transcription Factor; Vascular Endothelial Growth Factor A | 2015 |
Anterior gradient 2 is a binding stabilizer of hypoxia inducible factor-1α that enhances CoCl2 -induced doxorubicin resistance in breast cancer cells.
Topics: Antineoplastic Agents; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cobalt; Doxorubicin; Drug Resistance, Neoplasm; Female; Fluorescent Antibody Technique; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunoprecipitation; Mucoproteins; Oncogene Proteins; Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Transfection | 2015 |
Copper depletion inhibits CoCl2-induced aggressive phenotype of MCF-7 cells via downregulation of HIF-1 and inhibition of Snail/Twist-mediated epithelial-mesenchymal transition.
Topics: Animals; Antineoplastic Agents, Alkylating; Breast Neoplasms; Cation Transport Proteins; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Polarity; Cobalt; Copper; Copper Transporter 1; Down-Regulation; Epithelial-Mesenchymal Transition; Female; Fibronectins; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; MCF-7 Cells; Mice; Mice, Inbred BALB C; Nuclear Proteins; Phenotype; RNA Interference; RNA, Small Interfering; Signal Transduction; Snail Family Transcription Factors; Transcription Factors; Transcriptional Activation; Transplantation, Heterologous; Triethylenephosphoramide; Twist-Related Protein 1; Vimentin | 2015 |
CA IX is upregulated in CoCl2-induced hypoxia and associated with cell invasive potential and a poor prognosis of breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Antigens, Neoplasm; Biomarkers, Tumor; Breast Neoplasms; Carbonic Anhydrase IX; Carbonic Anhydrases; Cell Hypoxia; Cell Proliferation; Cobalt; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; MCF-7 Cells; Middle Aged; Prognosis; Transcriptional Activation | 2016 |
The number of polyploid giant cancer cells and epithelial-mesenchymal transition-related proteins are associated with invasion and metastasis in human breast cancer.
Topics: Adult; Breast Neoplasms; Cadherins; Cell Line, Tumor; Cobalt; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Giant Cells; Humans; Lymphatic Metastasis; MCF-7 Cells; Middle Aged; Neoplasm Invasiveness; Polyploidy; Vimentin | 2015 |
Inhibitory role of TRIP-Br1 oncoprotein in hypoxia-induced apoptosis in breast cancer cell lines.
Topics: Animals; Apoptosis; Breast Neoplasms; Cell Hypoxia; Cell Line, Tumor; Cobalt; Down-Regulation; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Mice; NIH 3T3 Cells; Nuclear Proteins; Trans-Activators; Transcription Factors; Up-Regulation; X-Linked Inhibitor of Apoptosis Protein | 2016 |
The Promoting Effect of Radiation on Glucose Metabolism in Breast Cancer Cells under the Treatment of Cobalt Chloride.
Topics: Breast Neoplasms; Cell Hypoxia; Cell Line, Tumor; Cobalt; Female; Glucose; Glucose Transporter Type 1; Hexokinase; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; MCF-7 Cells; RNA, Messenger | 2017 |
Impact of hypoxia inducible factors on estrogen receptor expression in breast cancer cells.
Topics: Breast Neoplasms; Cobalt; Disease Progression; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Female; Gene Expression Regulation, Neoplastic; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; MCF-7 Cells; Oxygen | 2017 |
Hypoxia-induced human endonuclease G expression suppresses tumor growth in a xenograft model.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cobalt; Endodeoxyribonucleases; Female; Genetic Therapy; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Mice; Mice, SCID; Microscopy, Fluorescence; Neoplasms; Promoter Regions, Genetic; Prostatic Neoplasms; Tumor Burden; Xenograft Model Antitumor Assays | 2008 |
Cobalt chloride-induced hypoxia modulates the invasive potential and matrix metalloproteinases of primary and metastatic breast cancer cells.
Topics: Adenocarcinoma; Antimutagenic Agents; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Cobalt; Collagen; Drug Combinations; Female; Gene Expression Regulation, Neoplastic; Humans; Hypoxia; Laminin; Matrix Metalloproteinases; Neoplasm Invasiveness; Proteoglycans; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tissue Inhibitor of Metalloproteinases | 2009 |
miR-20b modulates VEGF expression by targeting HIF-1 alpha and STAT3 in MCF-7 breast cancer cells.
Topics: Binding Sites; Breast Neoplasms; Cell Hypoxia; Cell Line, Tumor; Cobalt; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; MicroRNAs; Promoter Regions, Genetic; RNA Interference; Signal Transduction; STAT3 Transcription Factor; Time Factors; Transfection; Vascular Endothelial Growth Factor A | 2010 |
Hypoxia and metabolic phenotypes during breast carcinogenesis: expression of HIF-1alpha, GLUT1, and CAIX.
Topics: Antigens, Neoplasm; Antimutagenic Agents; Blotting, Western; Breast Neoplasms; Carbonic Anhydrase IX; Carbonic Anhydrases; Carcinoma in Situ; Carcinoma, Ductal, Breast; Cell Hypoxia; Cell Line, Tumor; Cobalt; Female; Gene Expression; Glucose Transporter Type 1; Humans; Hyperplasia; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Phenotype; Precancerous Conditions; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2010 |
Hypoxia induces proteasome-dependent degradation of estrogen receptor alpha in ZR-75 breast cancer cells.
Topics: Breast Neoplasms; Cell Division; Cell Hypoxia; Cobalt; Cysteine Endopeptidases; Endothelial Growth Factors; Estradiol; Estrogen Receptor alpha; Female; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Intercellular Signaling Peptides and Proteins; Leupeptins; Lymphokines; Multienzyme Complexes; Promoter Regions, Genetic; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteins; Receptors, Estrogen; Response Elements; Sp1 Transcription Factor; Transcription Factors; Transcriptional Activation; Trefoil Factor-1; Tumor Cells, Cultured; Tumor Suppressor Proteins; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2002 |
Hypoxia and estrogen receptor profile influence the responsiveness of human breast cancer cells to estradiol and antiestrogens.
Topics: Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Hypoxia; Cobalt; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogen Receptor Modulators; Female; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Receptors, Estrogen; Tamoxifen; Transcription Factors; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A | 2004 |
Expression of the pro-angiogenic factors vascular endothelial growth factor and interleukin-8/CXCL8 by human breast carcinomas is responsive to nutrient deprivation and endoplasmic reticulum stress.
Topics: Adenocarcinoma; Amino Acids; Breast Neoplasms; CCAAT-Enhancer-Binding Proteins; Cell Hypoxia; Cobalt; DNA Damage; DNA, Neoplasm; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Gene Expression Regulation, Neoplastic; Glucose; Glutamine; Humans; Interleukin-8; Neovascularization, Pathologic; RNA, Messenger; RNA, Neoplasm; Transcription Factor CHOP; Transcription Factors; Tumor Cells, Cultured; Tunicamycin; Up-Regulation; Vascular Endothelial Growth Factors | 2004 |
Cobalt chloride-induced estrogen receptor alpha down-regulation involves hypoxia-inducible factor-1alpha in MCF-7 human breast cancer cells.
Topics: Antimutagenic Agents; Breast Neoplasms; Cobalt; DNA-Binding Proteins; Down-Regulation; Estrogen Receptor alpha; Female; Herpes Simplex Virus Protein Vmw65; Humans; Hypoxia; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Nuclear Proteins; Protein Biosynthesis; Recombinant Fusion Proteins; Transcription Factors | 2005 |
Overexpression of Endothelin-A-receptor in breast cancer: regulation by estradiol and cobalt-chloride induced hypoxia.
Topics: Adult; Aged; Aged, 80 and over; Antimutagenic Agents; Blotting, Western; Breast Neoplasms; Cobalt; Disease Progression; Estradiol; Female; Humans; Immunohistochemistry; Middle Aged; Receptor, Endothelin A; Receptor, Endothelin B; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Up-Regulation | 2005 |
Selective ETAR antagonist atrasentan inhibits hypoxia-induced breast cancer cell invasion.
Topics: Antineoplastic Agents; Aspartic Acid Endopeptidases; Atrasentan; Breast Neoplasms; Cell Hypoxia; Cell Line, Tumor; Cell Movement; Cobalt; Endothelin A Receptor Antagonists; Endothelin-1; Endothelin-Converting Enzymes; Female; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Metalloendopeptidases; Neoplasm Invasiveness; Neoplasm Staging; Pyrrolidines; Receptor, Endothelin A; Time Factors; Up-Regulation | 2008 |
Low dose geldanamycin inhibits hepatocyte growth factor and hypoxia-stimulated invasion of cancer cells.
Topics: Antibiotics, Antineoplastic; Benzoquinones; Breast Neoplasms; Carcinoma; Cell Hypoxia; Cell Line, Tumor; Cobalt; Dose-Response Relationship, Drug; Down-Regulation; Drug Screening Assays, Antitumor; Extracellular Matrix Proteins; Feedback, Physiological; Female; Fibronectins; Focal Adhesions; Gene Expression Regulation, Neoplastic; Hepatocyte Growth Factor; HSP90 Heat-Shock Proteins; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Integrin beta3; Lactams, Macrocyclic; Neoplasm Invasiveness; Neoplasm Proteins; Neovascularization, Pathologic; Proto-Oncogene Proteins c-met; Stress Fibers; Urinary Bladder Neoplasms; Vascular Endothelial Growth Factor A | 2007 |
Cobaltous chloride and hypoxia inhibit aryl hydrocarbon receptor-mediated responses in breast cancer cells.
Topics: Antimutagenic Agents; Blotting, Northern; Breast Neoplasms; Cell Hypoxia; Cell Line, Tumor; Cell Nucleus; Cobalt; Cycloheximide; Cytochrome P-450 CYP1A1; Cytosol; Drug Antagonism; Environmental Pollutants; Enzyme Induction; Female; Gene Expression; Humans; Polychlorinated Dibenzodioxins; Protein Synthesis Inhibitors; Receptors, Aryl Hydrocarbon; RNA, Messenger; Ubiquitin-Protein Ligases | 2007 |
Mechanism of leptin expression in breast cancer cells: role of hypoxia-inducible factor-1alpha.
Topics: Active Transport, Cell Nucleus; Binding Sites; Breast Neoplasms; Cell Hypoxia; Cell Nucleus; Cobalt; Gene Expression Regulation, Neoplastic; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Insulin; Leptin; p300-CBP Transcription Factors; Promoter Regions, Genetic; Protein Binding; Transcriptional Activation; Tumor Cells, Cultured | 2008 |
uPAR induces epithelial-mesenchymal transition in hypoxic breast cancer cells.
Topics: Animals; Antimutagenic Agents; Breast Neoplasms; Cadherins; Cell Line, Tumor; Cell Membrane; Cell Movement; Cobalt; Collagen; Enzyme Activation; Epithelium; Female; Green Fluorescent Proteins; Humans; Hypoxia; Mesoderm; Neoplasm Invasiveness; Neoplasm Metastasis; Oxygen; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; rac1 GTP-Binding Protein; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; Signal Transduction; Snail Family Transcription Factors; Transcription Factors | 2007 |
The low-density lipoprotein receptor-related protein regulates cancer cell survival and metastasis development.
Topics: Animals; Breast Neoplasms; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Cobalt; Gene Silencing; Humans; Low Density Lipoprotein Receptor-Related Protein-1; Lung Neoplasms; Mice; Mice, SCID; Neoplasm Transplantation; Oxygen; RNA, Messenger; RNA, Small Interfering; Transplantation, Heterologous; Vascular Endothelial Growth Factor A | 2007 |
Nickel-induced transformation shifts the balance between HIF-1 and p53 transcription factors.
Topics: 3T3 Cells; Adenocarcinoma; Animals; Bone Neoplasms; Breast Neoplasms; Bronchi; Cadmium Chloride; Carcinogens, Environmental; Cell Hypoxia; Cell Transformation, Neoplastic; Cobalt; Cricetinae; Cricetulus; DNA-Binding Proteins; Epithelial Cells; Fibroblasts; Gene Expression Regulation; Genes, p53; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Lung Neoplasms; Mice; Neoplasm Proteins; Nickel; Nuclear Proteins; Osteosarcoma; Promoter Regions, Genetic; Recombinant Fusion Proteins; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 1999 |
Redox regulation of p53 during hypoxia.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acetylcysteine; Animals; Antioxidants; Breast Neoplasms; Carcinoma; Cell Cycle; Cell Death; Cell Division; Cell Hypoxia; Cells, Cultured; Chick Embryo; Cobalt; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Ditiocarb; Fibroblasts; Fluoresceins; Humans; Hydrogen Peroxide; Mice; Mitochondria; Myocardium; Reactive Oxygen Species; Rotenone; Superoxide Dismutase; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Uncoupling Agents | 2000 |