cmx-001 has been researched along with Molluscum-Contagiosum* in 1 studies
1 other study(ies) available for cmx-001 and Molluscum-Contagiosum
| Article | Year |
|---|---|
Detection of molluscum contagiosum virus (MCV) DNA in the plasma of an immunocompromised patient and possible reduction of MCV DNA with CMX-001.
Molluscum contagiosum virus (MCV) is a poxvirus that causes localized papules in healthy persons. We evaluated a woman with severe immunodeficiency and disseminated MCV. During treatment with CMX-001, an antiviral with activity against other poxviruses, MCV DNA was detected in 20% of plasma samples. When the patient was not receiving CMX-001, MCV DNA was detected in 50% of samples. We also noted improvement in warts on her fingers during CMX-001 therapy. Although MCV is caused by direct inoculation of virus into skin in healthy persons, in a severely immunocompromised person MCV DNA was present in blood and may spread by viremia. Topics: Adult; Antiviral Agents; Compassionate Use Trials; Cytosine; DNA, Viral; Female; Humans; Immunologic Deficiency Syndromes; Molluscum Contagiosum; Molluscum contagiosum virus; Organophosphonates; Real-Time Polymerase Chain Reaction; Young Adult | 2012 |