clozapine-n-oxide and Amyotrophic-Lateral-Sclerosis

clozapine-n-oxide has been researched along with Amyotrophic-Lateral-Sclerosis* in 1 studies

Other Studies

1 other study(ies) available for clozapine-n-oxide and Amyotrophic-Lateral-Sclerosis

Article	Year
Accessory respiratory muscles enhance ventilation in ALS model mice and are activated by excitatory V2a neurons. Experimental neurology, 2017, Volume: 287, Issue:Pt 2 Inspiratory accessory respiratory muscles (ARMs) enhance ventilation when demands are high, such as during exercise and/or pathological conditions. Despite progressive degeneration of phrenic motor neurons innervating the diaphragm, amyotrophic lateral sclerosis (ALS) patients and rodent models are able to maintain ventilation at early stages of disease. In order to assess the contribution of ARMs to respiratory compensation in ALS, we examined the activity of ARMs and ventilation throughout disease progression in SOD1 Topics: Amyotrophic Lateral Sclerosis; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Brain Stem; Clozapine; Disease Models, Animal; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Homeodomain Proteins; Humans; Interneurons; Male; Membrane Potentials; Mice; Mice, Transgenic; Plasma Membrane Neurotransmitter Transport Proteins; Receptor, Muscarinic M3; Receptors, Muscarinic; Respiration; Respiratory Muscles; Spinal Cord; Superoxide Dismutase; Transcription Factors	2017

Article

Year

Accessory respiratory muscles enhance ventilation in ALS model mice and are activated by excitatory V2a neurons.

Experimental neurology, 2017, Volume: 287, Issue:Pt 2

Inspiratory accessory respiratory muscles (ARMs) enhance ventilation when demands are high, such as during exercise and/or pathological conditions. Despite progressive degeneration of phrenic motor neurons innervating the diaphragm, amyotrophic lateral sclerosis (ALS) patients and rodent models are able to maintain ventilation at early stages of disease. In order to assess the contribution of ARMs to respiratory compensation in ALS, we examined the activity of ARMs and ventilation throughout disease progression in SOD1

Topics: Amyotrophic Lateral Sclerosis; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Brain Stem; Clozapine; Disease Models, Animal; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Homeodomain Proteins; Humans; Interneurons; Male; Membrane Potentials; Mice; Mice, Transgenic; Plasma Membrane Neurotransmitter Transport Proteins; Receptor, Muscarinic M3; Receptors, Muscarinic; Respiration; Respiratory Muscles; Spinal Cord; Superoxide Dismutase; Transcription Factors

2017