clozapine and Liver-Failure--Acute

clozapine has been researched along with Liver-Failure--Acute* in 3 studies

Reviews

1 review(s) available for clozapine and Liver-Failure--Acute

Article	Year
Use of N-Acetylcysteine for Clozapine-Induced Acute Liver Injury: A Case Report and Literature Review. Journal of pharmacy practice, 2023, Volume: 36, Issue:2 Topics: Acetylcysteine; Chemical and Drug Induced Liver Injury; Clozapine; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Liver Failure, Acute; Middle Aged	2023

Other Studies

2 other study(ies) available for clozapine and Liver-Failure--Acute

Article	Year
Re: Recent case report of clozapine-induced acute hepatic failure. Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 2010, Volume: 24, Issue:12 Topics: Antipsychotic Agents; Clozapine; Humans; Liver Failure, Acute; Male; Middle Aged; Schizophrenia	2010
Clozapine-induced fatal fulminant hepatic failure: a case report. Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 2009, Volume: 23, Issue:5 Fulminant hepatic failure (FHF) refers to the rapid development of severe acute liver injury with impaired synthetic function and encephalopathy in a person who previously had a normal liver or had wellcompensated liver disease. The potential causes of FHF are numerous, but viral or toxin-induced hepatitis are the most common. Clozapineinduced hepatotoxicity has rarely been reported in the literature, occurs via an unknown mechanism and results in liver biochemical abnormalities that are usually of no clinical significance. In approximately 30% to 50% of patients treated with clozapine, there is an asymptomatic rise in serum aminotransaminase levels; however, there are no current guidelines for routine monitoring of liver function tests and liver enzymes during its use. Fatal fulminant hepatitis has only been reported in three patients receiving clozapine. A case of fatal FHF that occurred in a schizophrenic woman who began clozapine therapy shortly before her illness developed is described. Topics: Antipsychotic Agents; Clozapine; Diagnosis, Differential; Fatal Outcome; Female; Humans; Liver Failure, Acute; Middle Aged; Schizophrenia, Paranoid	2009

Article

Year

Re: Recent case report of clozapine-induced acute hepatic failure.

Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 2010, Volume: 24, Issue:12

Topics: Antipsychotic Agents; Clozapine; Humans; Liver Failure, Acute; Male; Middle Aged; Schizophrenia

2010

Clozapine-induced fatal fulminant hepatic failure: a case report.

Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 2009, Volume: 23, Issue:5

Fulminant hepatic failure (FHF) refers to the rapid development of severe acute liver injury with impaired synthetic function and encephalopathy in a person who previously had a normal liver or had wellcompensated liver disease. The potential causes of FHF are numerous, but viral or toxin-induced hepatitis are the most common. Clozapineinduced hepatotoxicity has rarely been reported in the literature, occurs via an unknown mechanism and results in liver biochemical abnormalities that are usually of no clinical significance. In approximately 30% to 50% of patients treated with clozapine, there is an asymptomatic rise in serum aminotransaminase levels; however, there are no current guidelines for routine monitoring of liver function tests and liver enzymes during its use. Fatal fulminant hepatitis has only been reported in three patients receiving clozapine. A case of fatal FHF that occurred in a schizophrenic woman who began clozapine therapy shortly before her illness developed is described.

Topics: Antipsychotic Agents; Clozapine; Diagnosis, Differential; Fatal Outcome; Female; Humans; Liver Failure, Acute; Middle Aged; Schizophrenia, Paranoid

2009