clozapine has been researched along with Hepatic-Encephalopathy* in 2 studies
2 other study(ies) available for clozapine and Hepatic-Encephalopathy
| Article | Year |
|---|---|
Fatal acute fulminant liver failure due to clozapine: a case report and review of clozapine-induced hepatotoxicity.
Clozapine-induced hepatotoxicity is not well known and is usually of no clinical significance. This report describes fatal acute fulminant liver failure caused by clozapine in a 39-year-old man with chronic paranoid schizophrenia. The hepatotoxicity of clozapine is reviewed. Asymptomatic elevation of transaminase levels is observed most commonly, affecting between 30% and 50% of patients. Icteric hepatitis is uncommon, noted in 84 of 136,000 patients (0.06%). Fatal acute fulminant hepatitis has been documented in 2 patients (0.001%). The mechanism of clozapine hepatotoxicity is unknown. Although serious toxicity is rare, prescribers of clozapine should be aware of the hepatotoxic potential. Topics: Acute Disease; Adult; Clozapine; Fatal Outcome; Hepatic Encephalopathy; Humans; Liver; Male; Schizophrenia, Paranoid | 1997 |
Hepatic encephalopathy associated with combined clozapine and divalproex sodium treatment.
Topics: Adult; Clozapine; Drug Interactions; Enzyme Inhibitors; Female; Hepatic Encephalopathy; Humans; Serotonin Antagonists; Valproic Acid | 1997 |