clozapine and Cholestasis--Intrahepatic

clozapine has been researched along with Cholestasis--Intrahepatic* in 1 studies

Other Studies

1 other study(ies) available for clozapine and Cholestasis--Intrahepatic

Article	Year
[Clozapine-induced cholestatic jaundice: a case report]. Zeitschrift fur Gastroenterologie, 1989, Volume: 27, Issue:7 We report on a patient who became jaundiced during treatment with clozapine (Leponex). Histologically, cholestatic hepatitis with single-cell necroses of hepatocytes and infiltration of the portal zones with eosinophilic granulocytes were found. The patient recovered after discontinuation of clozapine, and liver function tests returned to normal within 4 weeks. This adverse effect of clozapine suggests that this "atypical" tricyclic neuroleptic resembles the phenothiazines both with regard to therapeutic spectrum and side effects. Topics: Aged; Autistic Disorder; Cholestasis, Intrahepatic; Clozapine; Dibenzazepines; Female; Humans; Liver	1989

Article

Year

[Clozapine-induced cholestatic jaundice: a case report].

Zeitschrift fur Gastroenterologie, 1989, Volume: 27, Issue:7

We report on a patient who became jaundiced during treatment with clozapine (Leponex). Histologically, cholestatic hepatitis with single-cell necroses of hepatocytes and infiltration of the portal zones with eosinophilic granulocytes were found. The patient recovered after discontinuation of clozapine, and liver function tests returned to normal within 4 weeks. This adverse effect of clozapine suggests that this "atypical" tricyclic neuroleptic resembles the phenothiazines both with regard to therapeutic spectrum and side effects.

Topics: Aged; Autistic Disorder; Cholestasis, Intrahepatic; Clozapine; Dibenzazepines; Female; Humans; Liver

1989