clove and Sexually-Transmitted-Diseases--Bacterial

Topics: Candidiasis, Vulvovaginal; Coinfection; Female; Health Services Needs and Demand; Humans; Madagascar; Rape; Retrospective Studies; Sexually Transmitted Diseases; Sexually Transmitted Diseases, Bacterial; Urban Population

In settings in which adequate laboratory service is lacking, the coexistence of urogenital schistosomiasis and sexually transmitted infections (STIs) poses a diagnostic challenge for health care providers in the management of patients with urogenital complaints.. Symptoms were recorded with use of a semistructured questionnaire at baseline and in follow-up surveys after STI and Schistosoma haematobium infection had been assessed and systematically treated as part of a community-based study of 253 women and 236 men, aged 15-49 years, living in an area of Madagascar where S. haematobium is endemic.. Of those infected with S. haematobium, 35% of the women had concordant STI (e.g., infection with Neisseria gonorrhoeae, Chlamydia trachomatis, Mycoplasma genitalium, and/or Trichomonas vaginalis), compared with 17% of the men. Both S. haematobium infection and STI were significantly more common among younger individuals, aged 15-24 years, than among older individuals. A broad spectrum of urogenital symptoms was reported. However, one-half of the women and men who had positive test results for an STI or for S. haematobium infection were asymptomatic. Gross hematuria and dysuria were, in multivariate analysis, associated with S. haematobium infection, as were genitopelvic discomfort in women and ejaculation pain in men. The association became stronger with higher intensity of infection. In bivariate analysis but not in the multiregression model, STI was associated with vaginal discharge and genitopelvic discomfort in women and was associated with urethral discharge in men.. The rationale for empirical antischistosoma treatment of adolescents and younger adults in areas where S. haematobium is endemic, with praziquantel alone or in combination with existing anti-STI regimens, is discussed.

Topics: Adolescent; Adult; Animals; Chlamydia Infections; Chlamydia trachomatis; Female; Humans; Madagascar; Male; Middle Aged; Mycoplasma genitalium; Mycoplasma Infections; Schistosoma haematobium; Schistosomiasis haematobia; Sexually Transmitted Diseases, Bacterial; Trichomonas vaginalis; Trichomonas Vaginitis; Young Adult

Topics: Adolescent; Adult; Aged; Antibodies, Bacterial; Female; Hepatitis B Surface Antigens; HIV Antibodies; Humans; Madagascar; Male; Middle Aged; Prisoners; Risk Factors; Sex Work; Sexually Transmitted Diseases, Bacterial; Sexually Transmitted Diseases, Viral; Treponema pallidum