clove and Eye-Infections--Parasitic

Topics: Animals; Blindness; Eye Infections, Parasitic; Female; Humans; Madagascar; Slit Lamp Microscopy; Toxocara canis; Toxocariasis; Ultrasonography; Vitrectomy; Young Adult

In addition to the unique physiological and immunological features of the eye, previously presented, some parasitic factors of recent knowledge are induced during ocular cysticercosis. A modulation of the immune response of the host, mediated by larval products (a soluble RNA-peptide, some metacestode surface sphingoglycolipids) seems to occur in vivo. These recent findings lead us to make a critical review of the antigenic profiles obtained by Enzyme-linked immunoelectrotransfer blot assay (EITB) on samples collected from malagasy patients.

Topics: Adolescent; Adult; Animals; Antibodies, Helminth; Child; Child, Preschool; Cysticercosis; Enzyme-Linked Immunosorbent Assay; Eye Infections, Parasitic; Female; Humans; Immune Tolerance; Immunoblotting; Inflammation; Madagascar; Male; Sensitivity and Specificity

Cysticercosis is due to cysticercus cellulosae and was know since a long time. Human is an intermediate occasional host by ingesting accidentally eggs of tenia. In Madagascar, neurocysticercosis are predominating (55%), occular localisations are not frequent (5%) and concerned particularly vitreous humour and retina. Diagnosis relies on serology: Elisa test, then Western Blot completed with research of circulating antibody and antigen in the acqueous humor by immocapture. Anatomopathologic test permits to confirm the diagnosis. Contribution of tomodensitometry is not conclusive therapeutic is summed up to a specific and symptomatic treatment with surgical extirpation when out means allow it.

Topics: Adult; Aged; Animals; Antibodies, Helminth; Child; Cysticercosis; Cysticercus; Eye Infections, Parasitic; Female; Humans; Madagascar; Male