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clotrimazole and Neoplasms

clotrimazole has been researched along with Neoplasms in 19 studies

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
"Oral clotrimazole is an effective agent for prophylaxis of oropharyngeal candidiasis in susceptible cancer patients."6.66Prophylaxis of oropharyngeal candidiasis with clotrimazole. ( Alvarado, T; Bodey, GP; Fainstein, V; Yeo, E, 1985)
"Oral clotrimazole is an effective agent for prophylaxis of oropharyngeal candidiasis in susceptible cancer patients."2.66Prophylaxis of oropharyngeal candidiasis with clotrimazole. ( Alvarado, T; Bodey, GP; Fainstein, V; Yeo, E, 1985)
"Patients with malignant neoplasms who were receiving chemotherapy and renal transplant recipients who were receiving immunosuppressives were randomized to receive either clotrimazole (10 mg) or placebo troches three times a day in a prospective, double-blinded study."2.65Prophylaxis of oral candidiasis with clotrimazole troches. ( Dekker, PT; Nightingale, CH; Owens, NJ; Quintiliani, R; Schauer, PK; Schweizer, RT, 1984)
"Treatment of cancer is increasingly effective but is associated with short and long term side effects."2.44Interventions for treating oral candidiasis for patients with cancer receiving treatment. ( Clarkson, JE; Eden, OB; Worthington, HV, 2007)
"Treatment of cancer is increasingly effective but is associated with short and long-term side effects."2.42Interventions for treating oral candidiasis for patients with cancer receiving treatment. ( Clarkson, JE; Eden, OB; Worthington, HV, 2004)
"Treatment of cancer is increasingly effective but is associated with short and long-term side effects."2.41Interventions for treating oral candidiasis for patients with cancer receiving treatment. ( Clarkson, JE; Eden, OB; Worthington, HV, 2002)
"A549 lung cancer cells or HCT-116 cells deficient in Bak and Bax were also resistant to apoptosis with the combination implicating the intrinsic apoptotic pathway."1.51Targeting mitochondrial hexokinases increases efficacy of histone deacetylase inhibitors in solid tumor models. ( Bates, SE; Curt, KM; Gottesman, MM; Kozlowski, H; McDonald, AJ; Patel, RP; Robey, RW; Sackett, DL, 2019)
"Diarrhea is a major side effect of ErbB receptor tyrosine kinase inhibitors (TKIs) in cancer chemotherapy."1.51Intestinal epithelial potassium channels and CFTR chloride channels activated in ErbB tyrosine kinase inhibitor diarrhea. ( Cil, O; Duan, T; Thiagarajah, JR; Verkman, AS, 2019)
"Clotrimazole (CTZ) has been proposed as an antitumoral agent because of its properties that inhibit glycolytic enzymes and detach them from the cytoskeleton."1.42Phosphatidylinositol-3-kinase as a putative target for anticancer action of clotrimazole. ( Carvalho, RS; Furtado, CM; Marcondes, MC; Sola-Penna, M; Zancan, P, 2015)
"Ketoconazole (KTZ) has been used as a second-line agent in hormone-refractory cancer therapy."1.32Tumor apoptosis induced by ruthenium(II)-ketoconazole is enhanced in nonsusceptible carcinoma by monoclonal antibody to EGF receptor. ( Anzellotti, A; Rieber, M; Sánchez-Delgado, RA; Strasberg Rieber, M, 2004)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19905 (26.32)18.7374
1990's0 (0.00)18.2507
2000's5 (26.32)29.6817
2010's6 (31.58)24.3611
2020's3 (15.79)2.80

Authors

AuthorsStudies
Diamandis, P1
Wildenhain, J1
Clarke, ID1
Sacher, AG1
Graham, J1
Bellows, DS1
Ling, EK1
Ward, RJ1
Jamieson, LG1
Tyers, M1
Dirks, PB1
Mayer, CD1
Bracher, F1
Lin, R1
Elf, S1
Shan, C1
Kang, HB1
Ji, Q1
Zhou, L1
Hitosugi, T1
Zhang, L1
Zhang, S1
Seo, JH1
Xie, J1
Tucker, M1
Gu, TL1
Sudderth, J1
Jiang, L1
Mitsche, M1
DeBerardinis, RJ1
Wu, S1
Li, Y1
Mao, H1
Chen, PR1
Wang, D1
Chen, GZ1
Hurwitz, SJ1
Lonial, S1
Arellano, ML1
Khoury, HJ1
Khuri, FR1
Lee, BH1
Lei, Q1
Brat, DJ1
Ye, K1
Boggon, TJ1
He, C1
Kang, S1
Fan, J1
Chen, J1
Cherukupalli, S1
Hampannavar, GA1
Chinnam, S1
Chandrasekaran, B1
Sayyad, N1
Kayamba, F1
Reddy Aleti, R1
Karpoormath, R1
Huryn, DM1
Kornfilt, DJP1
Wipf, P1
Peterková, L1
Kmoníčková, E1
Ruml, T1
Rimpelová, S1
da Silva Dos Reis Condé, CA1
de Andrade Querino, AL1
Silva, H1
Navarro, M1
McDonald, AJ1
Curt, KM1
Patel, RP1
Kozlowski, H1
Sackett, DL1
Robey, RW1
Gottesman, MM1
Bates, SE1
Duan, T1
Cil, O1
Thiagarajah, JR1
Verkman, AS1
Furtado, CM1
Marcondes, MC1
Carvalho, RS1
Sola-Penna, M1
Zancan, P1
Clarkson, JE3
Worthington, HV3
Eden, OB3
Strasberg Rieber, M1
Anzellotti, A1
Sánchez-Delgado, RA1
Rieber, M1
Sheklakov, ND1
Rukavishnikova, VM1
Quintiliani, R2
Owens, NJ2
Quercia, RA1
Klimek, JJ1
Nightingale, CH2
Shechtman, LB1
Funaro, L1
Robin, T1
Bottone, EJ1
Cuttner, J1
Schweizer, RT1
Schauer, PK1
Dekker, PT1
Yeo, E1
Alvarado, T1
Fainstein, V1
Bodey, GP1

Reviews

8 reviews available for clotrimazole and Neoplasms

ArticleYear
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
    Nature cell biology, 2015, Volume: 17, Issue:11

    Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms;

2015
An appraisal on synthetic and pharmaceutical perspectives of pyrazolo[4,3-d]pyrimidine scaffold.
    Bioorganic & medicinal chemistry, 2018, 01-15, Volume: 26, Issue:2

    Topics: Adenosine; Anti-Infective Agents; Antineoplastic Agents; Cytokinins; Enzyme Inhibitors; Humans; Mole

2018
p97: An Emerging Target for Cancer, Neurodegenerative Diseases, and Viral Infections.
    Journal of medicinal chemistry, 2020, 03-12, Volume: 63, Issue:5

    Topics: Acetanilides; Animals; Benzothiazoles; Drug Delivery Systems; Endoplasmic Reticulum; Humans; Neoplas

2020
Sarco/Endoplasmic Reticulum Calcium ATPase Inhibitors: Beyond Anticancer Perspective.
    Journal of medicinal chemistry, 2020, 03-12, Volume: 63, Issue:5

    Topics: Animals; Antineoplastic Agents; Enzyme Inhibitors; Gene Regulatory Networks; Humans; Neoplasms; Prot

2020
Interventions for treating oral candidiasis for patients with cancer receiving treatment.
    The Cochrane database of systematic reviews, 2004, Issue:1

    Topics: Antifungal Agents; Candidiasis, Oral; Clotrimazole; Humans; Ketoconazole; Neoplasms; Randomized Cont

2004
Interventions for treating oral candidiasis for patients with cancer receiving treatment.
    The Cochrane database of systematic reviews, 2007, Apr-18, Issue:2

    Topics: Antifungal Agents; Candidiasis, Oral; Clotrimazole; Humans; Ketoconazole; Neoplasms; Randomized Cont

2007
[Imidazole preparations in mycology].
    Vestnik dermatologii i venerologii, 1984, Issue:6

    Topics: Animals; Antifungal Agents; Candidiasis; Clotrimazole; Coccidioidomycosis; Cryptococcosis; Dermatomy

1984
Interventions for treating oral candidiasis for patients with cancer receiving treatment.
    The Cochrane database of systematic reviews, 2002, Issue:1

    Topics: Antifungal Agents; Candidiasis, Oral; Clotrimazole; Humans; Ketoconazole; Neoplasms; Randomized Cont

2002

Trials

4 trials available for clotrimazole and Neoplasms

ArticleYear
Treatment and prevention of oropharyngeal candidiasis.
    The American journal of medicine, 1984, Oct-30, Volume: 77, Issue:4D

    Topics: Adolescent; Adult; Aged; Aspergillosis; Candidiasis; Child; Child, Preschool; Clinical Trials as Top

1984
Clotrimazole treatment of oral candidiasis in patients with neoplastic disease.
    The American journal of medicine, 1984, Volume: 76, Issue:1

    Topics: Candidiasis, Oral; Clinical Trials as Topic; Clotrimazole; Double-Blind Method; Esophagitis; Humans;

1984
Prophylaxis of oral candidiasis with clotrimazole troches.
    Archives of internal medicine, 1984, Volume: 144, Issue:2

    Topics: Administration, Oral; Adult; Antineoplastic Agents; Candidiasis, Oral; Clinical Trials as Topic; Clo

1984
Prophylaxis of oropharyngeal candidiasis with clotrimazole.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1985, Volume: 3, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Candidiasis; Candidiasis, Oral; Clotrimazole; Diseas

1985

Other Studies

7 other studies available for clotrimazole and Neoplasms

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic

2007
Cytotoxic ring A-modified steroid analogues derived from Grundmann's ketone.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:8

    Topics: Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferatio

2011
Silver(I) complexes containing N-heterocyclic carbene azole drugs: Synthesis, characterization, cytotoxic activity, and their BSA interactions.
    Journal of inorganic biochemistry, 2023, Volume: 246

    Topics: Animals; Antineoplastic Agents; Azoles; Clotrimazole; Coordination Complexes; Humans; Ketoconazole;

2023
Targeting mitochondrial hexokinases increases efficacy of histone deacetylase inhibitors in solid tumor models.
    Experimental cell research, 2019, 02-15, Volume: 375, Issue:2

    Topics: A549 Cells; Antineoplastic Agents; Apoptosis; Clotrimazole; Depsipeptides; Drug Synergism; HCT116 Ce

2019
Intestinal epithelial potassium channels and CFTR chloride channels activated in ErbB tyrosine kinase inhibitor diarrhea.
    JCI insight, 2019, 02-21, Volume: 4, Issue:4

    Topics: Acetamides; Afatinib; Animals; Cell Membrane Permeability; Clotrimazole; Colon; Cystic Fibrosis Tran

2019
Phosphatidylinositol-3-kinase as a putative target for anticancer action of clotrimazole.
    The international journal of biochemistry & cell biology, 2015, Volume: 62

    Topics: Antineoplastic Agents; Apoptosis; Autophagy; Cell Division; Cell Survival; Clotrimazole; Energy Meta

2015
Tumor apoptosis induced by ruthenium(II)-ketoconazole is enhanced in nonsusceptible carcinoma by monoclonal antibody to EGF receptor.
    International journal of cancer, 2004, Nov-10, Volume: 112, Issue:3

    Topics: Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; bcl-2 Homologous

2004