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clotrimazole and Malaria

clotrimazole has been researched along with Malaria in 4 studies

Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.

Research Excerpts

ExcerptRelevanceReference
"The aim of present investigation was to evaluate the potential of clotrimazole as antimalarial drug."7.78Clotrimazole nanoemulsion for malaria chemotherapy. Part II: stability assessment, in vivo pharmacodynamic evaluations and toxicological studies. ( Borhade, V; Pathak, S; Patravale, V; Sharma, S, 2012)
"The aim of present investigation was to evaluate the potential of clotrimazole as antimalarial drug."3.78Clotrimazole nanoemulsion for malaria chemotherapy. Part II: stability assessment, in vivo pharmacodynamic evaluations and toxicological studies. ( Borhade, V; Pathak, S; Patravale, V; Sharma, S, 2012)
" The orally bioavailable lead imidazolopiperazine confers complete causal prophylactic protection (15 milligrams/kilogram) in rodent models of malaria and shows potent in vivo blood-stage therapeutic activity."1.37Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery. ( Barnes, SW; Bonamy, GM; Bopp, SE; Borboa, R; Bright, AT; Chatterjee, A; Che, J; Cohen, S; Dharia, NV; Diagana, TT; Fidock, DA; Froissard, P; Gagaring, K; Gettayacamin, M; Glynne, RJ; Gordon, P; Groessl, T; Kato, N; Kuhen, KL; Lee, MC; Mazier, D; McNamara, CW; Meister, S; Nagle, A; Nam, TG; Plouffe, DM; Richmond, W; Roland, J; Rottmann, M; Sattabongkot, J; Schultz, PG; Tuntland, T; Walker, JR; Winzeler, EA; Wu, T; Zhou, B; Zhou, Y, 2011)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Plouffe, D1
Brinker, A1
McNamara, C1
Henson, K1
Kato, N2
Kuhen, K1
Nagle, A2
Adrián, F1
Matzen, JT1
Anderson, P1
Nam, TG2
Gray, NS1
Chatterjee, A2
Janes, J1
Yan, SF1
Trager, R1
Caldwell, JS1
Schultz, PG2
Zhou, Y2
Winzeler, EA2
Meister, S1
Plouffe, DM1
Kuhen, KL1
Bonamy, GM1
Wu, T1
Barnes, SW1
Bopp, SE1
Borboa, R1
Bright, AT1
Che, J1
Cohen, S1
Dharia, NV1
Gagaring, K1
Gettayacamin, M1
Gordon, P1
Groessl, T1
Lee, MC1
McNamara, CW1
Fidock, DA1
Richmond, W1
Roland, J1
Rottmann, M2
Zhou, B1
Froissard, P1
Glynne, RJ1
Mazier, D1
Sattabongkot, J1
Tuntland, T1
Walker, JR1
Diagana, TT1
Gemma, S1
Camodeca, C1
Sanna Coccone, S1
Joshi, BP1
Bernetti, M1
Moretti, V1
Brogi, S1
Bonache de Marcos, MC1
Savini, L1
Taramelli, D1
Basilico, N1
Parapini, S1
Brun, R1
Lamponi, S1
Caccia, S1
Guiso, G1
Summers, RL1
Martin, RE1
Saponara, S1
Gorelli, B1
Novellino, E1
Campiani, G1
Butini, S1
Borhade, V1
Pathak, S1
Sharma, S1
Patravale, V1

Other Studies

4 other studies available for clotrimazole and Malaria

ArticleYear
In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen.
    Proceedings of the National Academy of Sciences of the United States of America, 2008, Jul-01, Volume: 105, Issue:26

    Topics: Animals; Antimalarials; Cluster Analysis; Computational Biology; Drug Evaluation, Preclinical; Drug

2008
Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery.
    Science (New York, N.Y.), 2011, Dec-09, Volume: 334, Issue:6061

    Topics: Animals; Antimalarials; Cell Line, Tumor; Drug Discovery; Drug Evaluation, Preclinical; Drug Resista

2011
Optimization of 4-aminoquinoline/clotrimazole-based hybrid antimalarials: further structure-activity relationships, in vivo studies, and preliminary toxicity profiling.
    Journal of medicinal chemistry, 2012, Aug-09, Volume: 55, Issue:15

    Topics: Aminoquinolines; Animals; Antimalarials; Biological Transport; Cell Line; Chloroquine; Clotrimazole;

2012
Clotrimazole nanoemulsion for malaria chemotherapy. Part II: stability assessment, in vivo pharmacodynamic evaluations and toxicological studies.
    International journal of pharmaceutics, 2012, Jul-15, Volume: 431, Issue:1-2

    Topics: Animals; Antimalarials; Clotrimazole; Disease Models, Animal; Drug Stability; Drug Storage; Emulsion

2012