Page last updated: 2024-10-25

clotrimazole and Lung Neoplasms

clotrimazole has been researched along with Lung Neoplasms in 4 studies

Lung Neoplasms: Tumors or cancer of the LUNG.

Research Excerpts

ExcerptRelevanceReference
" We investigated here the effect of clotrimazole (1-(alpha-2-chlorotrityl)imidazole), the antifungal azole derivative, which was recently recognized as calmodulin antagonist, on the levels of glucose 1,6-bisphosphate and fructose 1,6-bisphosphate, the two stimulatory signal molecules of glycolysis, and on ATP content and cell viability in LL/2 Lewis lung carcinoma cells and CT-26 colon adenocarcinoma cells."7.71Clotrimazole decreases glycolysis and the viability of lung carcinoma and colon adenocarcinoma cells. ( Beitner, R; Penso, J, 2002)
" We investigated here the effect of clotrimazole (1-(alpha-2-chlorotrityl)imidazole), the antifungal azole derivative, which was recently recognized as calmodulin antagonist, on the levels of glucose 1,6-bisphosphate and fructose 1,6-bisphosphate, the two stimulatory signal molecules of glycolysis, and on ATP content and cell viability in LL/2 Lewis lung carcinoma cells and CT-26 colon adenocarcinoma cells."3.71Clotrimazole decreases glycolysis and the viability of lung carcinoma and colon adenocarcinoma cells. ( Beitner, R; Penso, J, 2002)
"In vitro, treatment of NCI-H460 nonsmall cell lung cancer (NSCLC) cells with NC381 inhibited growth in a time-dependent manner."1.32NC381, a novel anticancer agent, arrests the cell cycle in G0-G1 and inhibits lung tumor cell growth in vitro and in vivo. ( Al-Qawasmeh, RA; Cao, MY; Feng, NP; Gu, XP; Jin, H; Lau, L; Lee, Y; Vassilakos, A; Viau, S; Wang, M; Wright, JA; Young, AH, 2004)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's3 (75.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Penso, J2
Beitner, R2
Cao, MY1
Lee, Y1
Feng, NP1
Al-Qawasmeh, RA1
Viau, S1
Gu, XP1
Lau, L1
Jin, H1
Wang, M1
Vassilakos, A1
Wright, JA1
Young, AH1
Benzaquen, LR1
Brugnara, C1
Byers, HR1
Gatton-Celli, S1
Halperin, JA1

Other Studies

4 other studies available for clotrimazole and Lung Neoplasms

ArticleYear
Detachment of glycolytic enzymes from cytoskeleton of Lewis lung carcinoma and colon adenocarcinoma cells induced by clotrimazole and its correlation to cell viability and morphology.
    Molecular genetics and metabolism, 2002, Volume: 76, Issue:3

    Topics: Adenocarcinoma; Animals; Carcinoma, Lewis Lung; Cell Survival; Clotrimazole; Colonic Neoplasms; Cyto

2002
Clotrimazole decreases glycolysis and the viability of lung carcinoma and colon adenocarcinoma cells.
    European journal of pharmacology, 2002, Sep-20, Volume: 451, Issue:3

    Topics: Adenocarcinoma; Adenosine Triphosphate; Animals; Calmodulin; Cell Survival; Clotrimazole; Colonic Ne

2002
NC381, a novel anticancer agent, arrests the cell cycle in G0-G1 and inhibits lung tumor cell growth in vitro and in vivo.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 308, Issue:2

    Topics: Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Cycle Proteins; Cel

2004
Clotrimazole inhibits cell proliferation in vitro and in vivo.
    Nature medicine, 1995, Volume: 1, Issue:6

    Topics: 3T3 Cells; Animals; Antineoplastic Agents; Calcium; Calcium Channel Blockers; Cattle; Cell Compartme

1995