clotrimazole has been researched along with Hemolysis in 8 studies
Hemolysis: The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Our recent study showed that clotrimazole has a relative high affinity for heme, inhibits reduced glutathione-dependent heme catabolism, and enhances heme-induced hemolysis." | 3.71 | Effect of antifungal azoles on the heme detoxification system of malarial parasite. ( Hara, S; Huy, NT; Kamei, K; Kanaori, K; Kondo, Y; Serada, S; Tajima, K; Takano, R, 2002) |
| "Clotrimazole (CLT) is an antifungal and antimalarial agent also effective as a Gardos channel inhibitor." | 1.35 | Clotrimazole enhances lysis of human erythrocytes induced by t-BHP. ( Ataullakhanov, FI; Lisovskaya, IL; Shcherbachenko, IM; Volkova, RI, 2009) |
| "Clotrimazole treatment resulted in worsening of anemia and hemolysis, with decreased red cell survival and increased numbers of circulating hyperchromic spherocytes and microspherocytes." | 1.33 | Evidence for a protective role of the Gardos channel against hemolysis in murine spherocytosis. ( Brugnara, C; De Franceschi, L; Fleming, MD; Gascard, P; Honczarenko, M; Mohandas, N; Peters, LL; Rivera, A, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (75.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jin, L | 1 |
| Bai, X | 1 |
| Luan, N | 1 |
| Yao, H | 1 |
| Zhang, Z | 1 |
| Liu, W | 1 |
| Chen, Y | 1 |
| Yan, X | 1 |
| Rong, M | 1 |
| Lai, R | 1 |
| Lu, Q | 1 |
| Lisovskaya, IL | 1 |
| Shcherbachenko, IM | 1 |
| Volkova, RI | 1 |
| Ataullakhanov, FI | 1 |
| Cueff, A | 1 |
| Seear, R | 1 |
| Dyrda, A | 1 |
| Bouyer, G | 1 |
| Egée, S | 1 |
| Esposito, A | 1 |
| Skepper, J | 1 |
| Tiffert, T | 1 |
| Lew, VL | 1 |
| Thomas, SL | 1 |
| Huy, NT | 3 |
| Takano, R | 3 |
| Hara, S | 3 |
| Kamei, K | 3 |
| Lang, PA | 1 |
| Kaiser, S | 1 |
| Myssina, S | 1 |
| Birka, C | 1 |
| Weinstock, C | 1 |
| Northoff, H | 1 |
| Wieder, T | 1 |
| Lang, F | 1 |
| Huber, SM | 1 |
| De Franceschi, L | 1 |
| Rivera, A | 1 |
| Fleming, MD | 1 |
| Honczarenko, M | 1 |
| Peters, LL | 1 |
| Gascard, P | 1 |
| Mohandas, N | 1 |
| Brugnara, C | 1 |
| Yamamoto, T | 1 |
| Kondo, Y | 2 |
| Kanaori, K | 2 |
| Tajima, K | 2 |
| Serada, S | 1 |
8 other studies available for clotrimazole and Hemolysis
| Article | Year |
|---|---|
A Designed Tryptophan- and Lysine/Arginine-Rich Antimicrobial Peptide with Therapeutic Potential for Clinical Antibiotic-Resistant Candida albicans Vaginitis.
Topics: Animals; Antimicrobial Cationic Peptides; Arginine; Candida albicans; Dose-Response Relationship, Dr | 2016 |
Clotrimazole enhances lysis of human erythrocytes induced by t-BHP.
Topics: Calcium; Clotrimazole; Erythrocytes; Glutathione; Hemin; Hemoglobins; Hemolysis; Humans; Oxidative S | 2009 |
Effects of elevated intracellular calcium on the osmotic fragility of human red blood cells.
Topics: Calcimycin; Calcium; Calcium Signaling; Cell Membrane Permeability; Cell Size; Cell-Derived Micropar | 2010 |
Enhancement of heme-induced membrane damage by the anti-malarial clotrimazole: the role of colloid-osmotic forces.
Topics: Animals; Antimalarials; Clotrimazole; Colloids; Erythrocyte Membrane; Heme; Hemolysis; Humans; In Vi | 2004 |
Effect of Vibrio parahaemolyticus haemolysin on human erythrocytes.
Topics: Annexins; Apoptosis; Calcium; Cations; Cell Membrane Permeability; Cell Size; Clotrimazole; Erythroc | 2004 |
Evidence for a protective role of the Gardos channel against hemolysis in murine spherocytosis.
Topics: Anemia, Hemolytic; Animals; Calcium; Clotrimazole; Cytoskeletal Proteins; Hemolysis; Kinetics; Membr | 2005 |
Clotrimazole binds to heme and enhances heme-dependent hemolysis: proposed antimalarial mechanism of clotrimazole.
Topics: Animals; Antimalarials; Clotrimazole; Glutathione; Heme; Hemolysis; Humans; Plasmodium falciparum; P | 2002 |
Effect of antifungal azoles on the heme detoxification system of malarial parasite.
Topics: Animals; Antifungal Agents; Antimalarials; Clotrimazole; Electron Spin Resonance Spectroscopy; Eryth | 2002 |