Head and Neck Neoplasms: Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651)
| Trial | Phase | Enrollment | Study Type | Start Date | Status |
|---|
| Randomized Evaluation of a Phytopharmaceutical in Prevention of Severe Oral Mucositis in Patients Receiving Radiotherapy for Oral Cavity, Oropharynx, Hypopharynx, or Cavum Cancer[NCT01066741] | Phase 3 | 78 participants (Actual) | Interventional | 2009-05-31 | Terminated (stopped due to insufficient recruitment, the planed sample size appears not achievable) |
| The Effectiveness of Topical Oral Vitamin D Gel in Prevention of Radiation-induced Oral Mucositis[NCT04308161] | Phase 2 | 45 participants (Anticipated) | Interventional | 2019-11-02 | Recruiting |
| The Effectiveness of Melatonin in Prevention of Radiation-induced Oral Mucositis[NCT03833570] | Phase 2 | 40 participants (Actual) | Interventional | 2018-01-12 | Completed |
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] |
| Article | Year |
|---|
Prophylaxis of radiation-associated mucositis in conventionally treated patients with head and neck cancer: a double-blind, phase III, randomized, controlled trial evaluating the clinical efficacy of an antimicrobial lozenge using a validated mucositis scJournal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-01, Volume: 20, Issue:19
Topics: Administration, Oral; Anti-Bacterial Agents; Anti-Infective Agents, Local; Bacitracin; Clotrimazole; | 2002 |
Quality of life, mucositis, and xerostomia from radiotherapy for head and neck cancers: a report from the NCIC CTG HN2 randomized trial of an antimicrobial lozenge to prevent mucositis.Head & neck, 2005, Volume: 27, Issue:5
Topics: Administration, Oral; Anti-Infective Agents; Bacitracin; Carcinoma, Squamous Cell; Clotrimazole; Dou | 2005 |
Quality of life, mucositis, and xerostomia from radiotherapy for head and neck cancers: a report from the NCIC CTG HN2 randomized trial of an antimicrobial lozenge to prevent mucositis.Head & neck, 2005, Volume: 27, Issue:5
Topics: Administration, Oral; Anti-Infective Agents; Bacitracin; Carcinoma, Squamous Cell; Clotrimazole; Dou | 2005 |
Quality of life, mucositis, and xerostomia from radiotherapy for head and neck cancers: a report from the NCIC CTG HN2 randomized trial of an antimicrobial lozenge to prevent mucositis.Head & neck, 2005, Volume: 27, Issue:5
Topics: Administration, Oral; Anti-Infective Agents; Bacitracin; Carcinoma, Squamous Cell; Clotrimazole; Dou | 2005 |
Quality of life, mucositis, and xerostomia from radiotherapy for head and neck cancers: a report from the NCIC CTG HN2 randomized trial of an antimicrobial lozenge to prevent mucositis.Head & neck, 2005, Volume: 27, Issue:5
Topics: Administration, Oral; Anti-Infective Agents; Bacitracin; Carcinoma, Squamous Cell; Clotrimazole; Dou | 2005 |
Quality of life, mucositis, and xerostomia from radiotherapy for head and neck cancers: a report from the NCIC CTG HN2 randomized trial of an antimicrobial lozenge to prevent mucositis.Head & neck, 2005, Volume: 27, Issue:5
Topics: Administration, Oral; Anti-Infective Agents; Bacitracin; Carcinoma, Squamous Cell; Clotrimazole; Dou | 2005 |
Quality of life, mucositis, and xerostomia from radiotherapy for head and neck cancers: a report from the NCIC CTG HN2 randomized trial of an antimicrobial lozenge to prevent mucositis.Head & neck, 2005, Volume: 27, Issue:5
Topics: Administration, Oral; Anti-Infective Agents; Bacitracin; Carcinoma, Squamous Cell; Clotrimazole; Dou | 2005 |
Quality of life, mucositis, and xerostomia from radiotherapy for head and neck cancers: a report from the NCIC CTG HN2 randomized trial of an antimicrobial lozenge to prevent mucositis.Head & neck, 2005, Volume: 27, Issue:5
Topics: Administration, Oral; Anti-Infective Agents; Bacitracin; Carcinoma, Squamous Cell; Clotrimazole; Dou | 2005 |
Quality of life, mucositis, and xerostomia from radiotherapy for head and neck cancers: a report from the NCIC CTG HN2 randomized trial of an antimicrobial lozenge to prevent mucositis.Head & neck, 2005, Volume: 27, Issue:5
Topics: Administration, Oral; Anti-Infective Agents; Bacitracin; Carcinoma, Squamous Cell; Clotrimazole; Dou | 2005 |
Quality of life, mucositis, and xerostomia from radiotherapy for head and neck cancers: a report from the NCIC CTG HN2 randomized trial of an antimicrobial lozenge to prevent mucositis.Head & neck, 2005, Volume: 27, Issue:5
Topics: Administration, Oral; Anti-Infective Agents; Bacitracin; Carcinoma, Squamous Cell; Clotrimazole; Dou | 2005 |
Prevention of mucositis in irradiated head and neck cancer patients.Journal of experimental therapeutics & oncology, 1996, Volume: 1, Issue:2
Topics: Ampicillin; Anti-Infective Agents; Ciprofloxacin; Clotrimazole; Drug Combinations; Gastrointestinal | 1996 |
A pilot study evaluating the safety and microbiologic efficacy of an economically viable antimicrobial lozenge in patients with head and neck cancer receiving radiation therapy.Head & neck, 2002, Volume: 24, Issue:1
Topics: Administration, Oral; Adult; Aged; Bacitracin; Carcinoma, Squamous Cell; Clotrimazole; Female; Follo | 2002 |