clotrimazole has been researched along with Colonic Neoplasms in 7 studies
Colonic Neoplasms: Tumors or cancer of the COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We investigated here the effect of clotrimazole (1-(alpha-2-chlorotrityl)imidazole), the antifungal azole derivative, which was recently recognized as calmodulin antagonist, on the levels of glucose 1,6-bisphosphate and fructose 1,6-bisphosphate, the two stimulatory signal molecules of glycolysis, and on ATP content and cell viability in LL/2 Lewis lung carcinoma cells and CT-26 colon adenocarcinoma cells." | 7.71 | Clotrimazole decreases glycolysis and the viability of lung carcinoma and colon adenocarcinoma cells. ( Beitner, R; Penso, J, 2002) |
| " We investigated here the effect of clotrimazole (1-(alpha-2-chlorotrityl)imidazole), the antifungal azole derivative, which was recently recognized as calmodulin antagonist, on the levels of glucose 1,6-bisphosphate and fructose 1,6-bisphosphate, the two stimulatory signal molecules of glycolysis, and on ATP content and cell viability in LL/2 Lewis lung carcinoma cells and CT-26 colon adenocarcinoma cells." | 3.71 | Clotrimazole decreases glycolysis and the viability of lung carcinoma and colon adenocarcinoma cells. ( Beitner, R; Penso, J, 2002) |
| "The growth-inhibitory effects of ketoconazole, an antifungal agent which inhibits arachidonic acid lipoxygenases and cytochrome P-450 enzymes, were tested in human colon and breast cancer cell lines." | 3.68 | Effects of ketoconazole on the proliferation and cell cycle of human cancer cell lines. ( Coudray, AM; Fagot, D; Forgue-Lafitte, ME; Mester, J, 1992) |
| " These results also validate that CLZ has significant anticancer activity both alone and in combination and support the strategy of drug repurposing coupled to drug combination for prostate cancer therapy." | 1.62 | Synergistic Interaction of CPP2 Coupled with Thiazole Derivates Combined with Clotrimazole and Antineoplastic Drugs in Prostate and Colon Cancer Cell Lines. ( Duarte, D; Vale, N, 2021) |
| "Apoptosis can be induced in colon cancer cell CCL229 by CLT at the concentration of 25-35 mumol/L in a dose and time dependent manner." | 1.31 | [Clotrimazole induced apoptosis in human colon cancer cell line CCL229]. ( Song, JD; Zhao, X, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Schuetz, EG | 1 |
| Beck, WT | 1 |
| Schuetz, JD | 1 |
| Duarte, D | 1 |
| Vale, N | 1 |
| Wang, Z | 1 |
| Xu, F | 1 |
| Hu, J | 1 |
| Zhang, H | 2 |
| Cui, L | 1 |
| Lu, W | 1 |
| He, W | 1 |
| Wang, X | 1 |
| Li, M | 1 |
| Xiong, W | 1 |
| Xie, C | 1 |
| Liu, Y | 1 |
| Zhou, P | 1 |
| Liu, J | 1 |
| Huang, P | 1 |
| Qin, XF | 1 |
| Xia, X | 1 |
| Penso, J | 2 |
| Beitner, R | 2 |
| Zhao, X | 1 |
| Song, JD | 1 |
| Forgue-Lafitte, ME | 1 |
| Coudray, AM | 1 |
| Fagot, D | 1 |
| Mester, J | 1 |
7 other studies available for clotrimazole and Colonic Neoplasms
| Article | Year |
|---|---|
Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells.
Topics: Adenocarcinoma; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Blotting, No | 1996 |
Synergistic Interaction of CPP2 Coupled with Thiazole Derivates Combined with Clotrimazole and Antineoplastic Drugs in Prostate and Colon Cancer Cell Lines.
Topics: Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell | 2021 |
Modulation of lactate-lysosome axis in dendritic cells by clotrimazole potentiates antitumor immunity.
Topics: Animals; Antineoplastic Agents; Basic-Leucine Zipper Transcription Factors; Cell Line, Tumor; Clotri | 2021 |
Detachment of glycolytic enzymes from cytoskeleton of Lewis lung carcinoma and colon adenocarcinoma cells induced by clotrimazole and its correlation to cell viability and morphology.
Topics: Adenocarcinoma; Animals; Carcinoma, Lewis Lung; Cell Survival; Clotrimazole; Colonic Neoplasms; Cyto | 2002 |
Clotrimazole decreases glycolysis and the viability of lung carcinoma and colon adenocarcinoma cells.
Topics: Adenocarcinoma; Adenosine Triphosphate; Animals; Calmodulin; Cell Survival; Clotrimazole; Colonic Ne | 2002 |
[Clotrimazole induced apoptosis in human colon cancer cell line CCL229].
Topics: Antineoplastic Agents; Apoptosis; Clotrimazole; Colonic Neoplasms; Flow Cytometry; Growth Inhibitors | 2002 |
Effects of ketoconazole on the proliferation and cell cycle of human cancer cell lines.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adenocarcinoma; Breast Neoplasms; Cell | 1992 |