clotrimazole has been researched along with Breast Neoplasms in 10 studies
Breast Neoplasms: Tumors or cancer of the human BREAST.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Clotrimazole presents deleterious effects on two human breast cancer cell lines metabolism, growth and migration, where the most aggressive cell line is more affected by the drug." | 7.78 | Clotrimazole preferentially inhibits human breast cancer cell proliferation, viability and glycolysis. ( de Souza, ML; Furtado, CM; Marcondes, MC; Sola-Penna, M; Zancan, P, 2012) |
| "Human breast cancer tissues, as well as normal tissues from the same patients, were treated with clotrimazole (CTZ) and have their capacities for glucose consumption and lactate production evaluated." | 7.77 | Clotrimazole disrupts glycolysis in human breast cancer without affecting non-tumoral tissues. ( Calaça, Ide C; Celestrini, Dde M; Coelho, RG; Correia, AH; Costa, MA; Sola-Penna, M, 2011) |
| "Clotrimazole (CLT) is an antifungal azole derivative with promising anticancer effects due to inhibiting the activity of glycolytic enzymes." | 5.42 | Combination of imatinib and clotrimazole enhances cell growth inhibition in T47D breast cancer cells. ( Fahim, SA; Motawi, TM; Sadik, NA; Shouman, SA, 2015) |
| "Clotrimazole is an anti-fungal azole derivative recently recognized as a calmodulin antagonist with promising anti-cancer effect." | 5.33 | Clotrimazole decreases human breast cancer cells viability through alterations in cytoskeleton-associated glycolytic enzymes. ( Da Poian, AT; de Freitas, MS; Holandino, C; Marinho-Carvalho, MM; Meira, DD; Sola-Penna, M; Teixeira, CA; Veiga, VF, 2005) |
| "Clotrimazole presents deleterious effects on two human breast cancer cell lines metabolism, growth and migration, where the most aggressive cell line is more affected by the drug." | 3.78 | Clotrimazole preferentially inhibits human breast cancer cell proliferation, viability and glycolysis. ( de Souza, ML; Furtado, CM; Marcondes, MC; Sola-Penna, M; Zancan, P, 2012) |
| "Human breast cancer tissues, as well as normal tissues from the same patients, were treated with clotrimazole (CTZ) and have their capacities for glucose consumption and lactate production evaluated." | 3.77 | Clotrimazole disrupts glycolysis in human breast cancer without affecting non-tumoral tissues. ( Calaça, Ide C; Celestrini, Dde M; Coelho, RG; Correia, AH; Costa, MA; Sola-Penna, M, 2011) |
| "The growth-inhibitory effects of ketoconazole, an antifungal agent which inhibits arachidonic acid lipoxygenases and cytochrome P-450 enzymes, were tested in human colon and breast cancer cell lines." | 3.68 | Effects of ketoconazole on the proliferation and cell cycle of human cancer cell lines. ( Coudray, AM; Fagot, D; Forgue-Lafitte, ME; Mester, J, 1992) |
| "Clotrimazole (CLT) is an antifungal azole derivative with promising anticancer effects due to inhibiting the activity of glycolytic enzymes." | 1.42 | Combination of imatinib and clotrimazole enhances cell growth inhibition in T47D breast cancer cells. ( Fahim, SA; Motawi, TM; Sadik, NA; Shouman, SA, 2015) |
| "Our results showed that, in the MCF-7 breast cancer cell line, PRL increased hIKCa1 current density." | 1.36 | Intermediate Ca2+-sensitive K+ channels are necessary for prolactin-induced proliferation in breast cancer cells. ( Ahidouch, A; Chopin, V; Faouzi, M; Ouadid-Ahidouch, H, 2010) |
| "Clotrimazole is an anti-fungal azole derivative recently recognized as a calmodulin antagonist with promising anti-cancer effect." | 1.33 | Clotrimazole decreases human breast cancer cells viability through alterations in cytoskeleton-associated glycolytic enzymes. ( Da Poian, AT; de Freitas, MS; Holandino, C; Marinho-Carvalho, MM; Meira, DD; Sola-Penna, M; Teixeira, CA; Veiga, VF, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 7 (70.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Muftuoglu, Y | 1 |
| Mustata, G | 1 |
| van Leeuwen, JE | 1 |
| Ba-Alawi, W | 1 |
| Branchard, E | 1 |
| Cruickshank, J | 1 |
| Schormann, W | 1 |
| Longo, J | 1 |
| Silvester, J | 1 |
| Gross, PL | 1 |
| Andrews, DW | 1 |
| Cescon, DW | 1 |
| Haibe-Kains, B | 1 |
| Penn, LZ | 1 |
| Gendoo, DMA | 1 |
| Neary, CL | 1 |
| Pastorino, JG | 1 |
| Motawi, TM | 1 |
| Sadik, NA | 1 |
| Fahim, SA | 1 |
| Shouman, SA | 1 |
| Marcondes, MC | 2 |
| Fernandes, AC | 1 |
| Itabaiana, I | 1 |
| de Souza, RO | 1 |
| Sola-Penna, M | 4 |
| Zancan, P | 2 |
| Faouzi, M | 1 |
| Chopin, V | 1 |
| Ahidouch, A | 1 |
| Ouadid-Ahidouch, H | 1 |
| Coelho, RG | 1 |
| Calaça, Ide C | 1 |
| Celestrini, Dde M | 1 |
| Correia, AH | 1 |
| Costa, MA | 1 |
| Furtado, CM | 1 |
| de Souza, ML | 1 |
| Meira, DD | 1 |
| Marinho-Carvalho, MM | 1 |
| Teixeira, CA | 1 |
| Veiga, VF | 1 |
| Da Poian, AT | 1 |
| Holandino, C | 1 |
| de Freitas, MS | 1 |
| Forgue-Lafitte, ME | 1 |
| Coudray, AM | 1 |
| Fagot, D | 1 |
| Mester, J | 1 |
10 other studies available for clotrimazole and Breast Neoplasms
| Article | Year |
|---|---|
Pharmacophore modeling strategies for the development of novel nonsteroidal inhibitors of human aromatase (CYP19).
Topics: Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Binding Sites; Breast Neoplasms; Computer Si | 2010 |
Computational pharmacogenomic screen identifies drugs that potentiate the anti-breast cancer activity of statins.
Topics: Breast Neoplasms; Cadherins; Cholesterol; Clotrimazole; Dipyridamole; Female; Humans; Hydroxymethylg | 2022 |
Akt inhibition promotes hexokinase 2 redistribution and glucose uptake in cancer cells.
Topics: Breast Neoplasms; Clotrimazole; Fatty Acids, Unsaturated; Female; Glucose; HeLa Cells; Hexokinase; H | 2013 |
Combination of imatinib and clotrimazole enhances cell growth inhibition in T47D breast cancer cells.
Topics: Adenosine Triphosphate; Antifungal Agents; Antineoplastic Agents; Benzamides; Breast; Breast Neoplas | 2015 |
Nanomicellar Formulation of Clotrimazole Improves Its Antitumor Action toward Human Breast Cancer Cells.
Topics: Adenosine Triphosphate; Antineoplastic Agents; Antioxidants; Apoptosis; Breast Neoplasms; Cell Line, | 2015 |
Intermediate Ca2+-sensitive K+ channels are necessary for prolactin-induced proliferation in breast cancer cells.
Topics: Breast Neoplasms; Calcium; Cell Line, Tumor; Cell Proliferation; Clotrimazole; Female; Humans; Inter | 2010 |
Clotrimazole disrupts glycolysis in human breast cancer without affecting non-tumoral tissues.
Topics: Actins; Anticarcinogenic Agents; Breast Neoplasms; Clotrimazole; Female; Glucose; Glycolysis; Humans | 2011 |
Clotrimazole preferentially inhibits human breast cancer cell proliferation, viability and glycolysis.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell S | 2012 |
Clotrimazole decreases human breast cancer cells viability through alterations in cytoskeleton-associated glycolytic enzymes.
Topics: Actins; Breast Neoplasms; Carcinoma, Ductal, Breast; Cell Line, Tumor; Cell Survival; Clotrimazole; | 2005 |
Effects of ketoconazole on the proliferation and cell cycle of human cancer cell lines.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adenocarcinoma; Breast Neoplasms; Cell | 1992 |