clotrimazole has been researched along with AIDS-Related Opportunistic Infections in 18 studies
AIDS-Related Opportunistic Infections: Opportunistic infections found in patients who test positive for human immunodeficiency virus (HIV). The most common include PNEUMOCYSTIS PNEUMONIA, Kaposi's sarcoma, cryptosporidiosis, herpes simplex, toxoplasmosis, cryptococcosis, and infections with Mycobacterium avium complex, Microsporidium, and Cytomegalovirus.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A systematic review of randomized clinical trials published between 1966 and April 2000 was undertaken to determine the strength of evidence for the effectiveness of antifungal drugs (nystatin, clotrimazole, amphotericin B, fluconazole, ketoconazole, and itraconazole) to prevent and treat oral candidiasis in human immunodeficiency virus-positive patients." | 4.81 | A systematic review of the effectiveness of antifungal drugs for the prevention and treatment of oropharyngeal candidiasis in HIV-positive patients. ( Bonito, AJ; Patton, LL; Shugars, DA, 2001) |
| "Fluconazole was also effective in preventing esophageal candidiasis (adjusted relative hazard, 5." | 2.68 | A randomized trial comparing fluconazole with clotrimazole troches for the prevention of fungal infections in patients with advanced human immunodeficiency virus infection. NIAID AIDS Clinical Trials Group. ( Carey, J; Eyster, ME; Feinberg, J; Finkelstein, D; Frame, P; He, W; Koletar, SL; Powderly, WG; van der Horst, C; Waskin, H, 1995) |
| "Fluconazole was more effective than clotrimazole in eradicating Candida from the oral flora by the end of therapy (65% versus 48%) (p = 0." | 2.67 | Therapy for oropharyngeal candidiasis in HIV-infected patients: a randomized, prospective multicenter study of oral fluconazole versus clotrimazole troches. The Multicenter Study Group. ( Debruin, M; Greenspan, D; Pons, V, 1993) |
| "The use of preventive treatment for fungal infections is cautioned due to the possibility of resistance to treatment." | 1.29 | Fungal infection overview. ( , 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (61.11) | 18.2507 |
| 2000's | 5 (27.78) | 29.6817 |
| 2010's | 2 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ray, A | 1 |
| Ray, S | 1 |
| George, AT | 1 |
| Swaminathan, N | 1 |
| Agwu, E | 1 |
| Ihongbe, JC | 1 |
| McManus, BA | 1 |
| Moran, GP | 1 |
| Coleman, DC | 1 |
| Sullivan, DJ | 1 |
| Powderly, WG | 2 |
| Finkelstein, D | 1 |
| Feinberg, J | 1 |
| Frame, P | 1 |
| He, W | 1 |
| van der Horst, C | 1 |
| Koletar, SL | 1 |
| Eyster, ME | 1 |
| Carey, J | 1 |
| Waskin, H | 1 |
| Clumeck, N | 1 |
| Sangeorzan, JA | 1 |
| Bradley, SF | 1 |
| He, X | 1 |
| Zarins, LT | 1 |
| Ridenour, GL | 1 |
| Tiballi, RN | 1 |
| Kauffman, CA | 1 |
| Pons, V | 1 |
| Greenspan, D | 1 |
| Debruin, M | 1 |
| Glatt, AE | 1 |
| Finkelstein, DM | 1 |
| Schoenfeld, DA | 1 |
| Stamenovic, E | 1 |
| Mahé, C | 1 |
| Gallant, JE | 1 |
| Ghannoum, MA | 1 |
| Mayer, KH | 1 |
| Navarro, EE | 1 |
| Perfect, JR | 1 |
| Pelletier, R | 1 |
| Peter, J | 1 |
| Antin, C | 1 |
| Gonzalez, C | 1 |
| Wood, L | 1 |
| Walsh, TJ | 1 |
| Linpiyawan, R | 1 |
| Jittreprasert, K | 1 |
| Sivayathorn, A | 1 |
| Cheng, B | 1 |
| Patton, LL | 1 |
| Bonito, AJ | 1 |
| Shugars, DA | 1 |
| Ellepola, AN | 1 |
| Samaranayake, LP | 1 |
| Martins, RS | 1 |
| Péreira, ES | 1 |
| Lima, SM | 1 |
| Senna, MI | 1 |
| Mesquita, RA | 1 |
| Santos, VR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized Comparative Study of Fluconazole Versus Clotrimazole Troches in the Prevention of Serious Fungal Infection in Patients With AIDS or Advanced AIDS-Related Complex. (A Nested Study of ACTG 081)[NCT00000676] | Phase 3 | 500 participants | Interventional | Completed | |||
| Fluconazole Prophylaxis of Thrush in AIDS[NCT00001542] | Phase 4 | 80 participants | Interventional | 1996-07-31 | Completed | ||
| Effect of Fluconazole, Clarithromycin, and Rifabutin on the Pharmacokinetics of Sulfamethoxazole and Dapsone and Their Hydroxylamine Metabolites[NCT00000826] | Phase 1 | 48 participants | Interventional | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for clotrimazole and AIDS-Related Opportunistic Infections
| Article | Year |
|---|---|
Interventions for prevention and treatment of vulvovaginal candidiasis in women with HIV infection.
Topics: Adult; AIDS-Related Opportunistic Infections; Antifungal Agents; Candidiasis, Vulvovaginal; Clotrima | 2011 |
Oropharyngeal candidiasis in patients with HIV: suggested guidelines for therapy.
Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; AIDS-Related Opportunistic Infections; Alg | 1999 |
A systematic review of the effectiveness of antifungal drugs for the prevention and treatment of oropharyngeal candidiasis in HIV-positive patients.
Topics: AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Candidiasis; Candidiasis, | 2001 |
Oral candidal infections and antimycotics.
Topics: AIDS-Related Opportunistic Infections; Amphotericin B; Anti-Infective Agents, Local; Antifungal Agen | 2000 |
4 trials available for clotrimazole and AIDS-Related Opportunistic Infections
| Article | Year |
|---|---|
A randomized trial comparing fluconazole with clotrimazole troches for the prevention of fungal infections in patients with advanced human immunodeficiency virus infection. NIAID AIDS Clinical Trials Group.
Topics: Adult; AIDS-Related Opportunistic Infections; CD4 Lymphocyte Count; Clotrimazole; Confidence Interva | 1995 |
A randomized trial comparing fluconazole with clotrimazole troches for the prevention of fungal infections in patients with advanced human immunodeficiency virus infection. NIAID AIDS Clinical Trials Group.
Topics: Adult; AIDS-Related Opportunistic Infections; CD4 Lymphocyte Count; Clotrimazole; Confidence Interva | 1995 |
A randomized trial comparing fluconazole with clotrimazole troches for the prevention of fungal infections in patients with advanced human immunodeficiency virus infection. NIAID AIDS Clinical Trials Group.
Topics: Adult; AIDS-Related Opportunistic Infections; CD4 Lymphocyte Count; Clotrimazole; Confidence Interva | 1995 |
A randomized trial comparing fluconazole with clotrimazole troches for the prevention of fungal infections in patients with advanced human immunodeficiency virus infection. NIAID AIDS Clinical Trials Group.
Topics: Adult; AIDS-Related Opportunistic Infections; CD4 Lymphocyte Count; Clotrimazole; Confidence Interva | 1995 |
Epidemiology of oral candidiasis in HIV-infected patients: colonization, infection, treatment, and emergence of fluconazole resistance.
Topics: Adult; AIDS-Related Opportunistic Infections; Candida; Candidiasis; Clotrimazole; Drug Resistance, M | 1994 |
Therapy for oropharyngeal candidiasis in HIV-infected patients: a randomized, prospective multicenter study of oral fluconazole versus clotrimazole troches. The Multicenter Study Group.
Topics: Administration, Oral; Adult; AIDS-Related Opportunistic Infections; Candidiasis, Oral; Clotrimazole; | 1993 |
Clinical trial: clotrimazole troche vs. itraconazole oral solution in the treatment of oral candidosis in AIDS patients.
Topics: Administration, Oral; Adolescent; Adult; AIDS-Related Opportunistic Infections; Antifungal Agents; C | 2000 |
10 other studies available for clotrimazole and AIDS-Related Opportunistic Infections
| Article | Year |
|---|---|
Distribution of yeast species associated with oral lesions in HIV-infected patients in Southwest Uganda.
Topics: Adolescent; Adult; Aged; AIDS-Related Opportunistic Infections; Antifungal Agents; Candida; Candidia | 2012 |
Drugs for AIDS and associated infections.
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Amphotericin B; Antifunga | 1995 |
Primary prophylaxis against opportunistic infections in patients with AIDS.
Topics: AIDS-Related Opportunistic Infections; Clotrimazole; Dapsone; Fluconazole; Humans; Mycoses; Pentamid | 1995 |
Therapy for oropharyngeal candidiasis in HIV-infected patients.
Topics: AIDS-Related Opportunistic Infections; Candidiasis, Oral; Clotrimazole; Fluconazole; HIV Infections; | 1993 |
Analysis of multiple failure time data from an AIDS clinical trial.
Topics: AIDS-Related Opportunistic Infections; Antifungal Agents; Candidiasis; Clinical Trials, Phase III as | 1997 |
Analysis of multiple failure time data from an AIDS clinical trial.
Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents, Local; Antifungal Agents; Candidiasis; | 1998 |
Emergence of resistance of Candida albicans to clotrimazole in human immunodeficiency virus-infected children: in vitro and clinical correlations.
Topics: Adolescent; AIDS-Related Opportunistic Infections; Antifungal Agents; Candida albicans; Candidiasis, | 2000 |
Preventing opportunistic infections.
Topics: Acyclovir; AIDS-Related Opportunistic Infections; Clarithromycin; Clindamycin; Clinical Trials as To | 1995 |
Fungal infection overview.
Topics: AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Blastomycosis; Candidiasis | 1995 |
Effect of commercial ethanol propolis extract on the in vitro growth of Candida albicans collected from HIV-seropositive and HIV-seronegative Brazilian patients with oral candidiasis.
Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antifungal Agents; Brazil; Candida alb | 2002 |