Compounds > closantel

Page last updated: 2024-08-23

closantel and Onchocerciasis

closantel has been researched along with Onchocerciasis in 4 studies

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	4 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Cho-Ngwa, F; Garner, AL; Gloeckner, C; Janda, KD; Lustigman, S; Samje, M; Tricoche, N; Zakhari, JS	1
Gooyit, M; Janda, KD; Lustigman, S; Tricoche, N	1
Eubanks, LM; Garner, AL; Gloeckner, C; Janda, KD; Kaufmann, GF; Lustigman, S; Mersha, F; Oksov, Y; Tricoche, N	1
Bocanegra-García, V; Correa-Basurto, J; Guo, X; Lizarazo-Ortega, C; Rodríguez-Pérez, MA; Segura-Cabrera, A	1

Other Studies

4 other study(ies) available for closantel and Onchocerciasis

Article	Year
Design, synthesis, and biological activities of closantel analogues: structural promiscuity and its impact on Onchocerca volvulus. Journal of medicinal chemistry, 2011, Jun-09, Volume: 54, Issue:11 Topics: Animals; Chitinases; Drug Design; Enzyme Inhibitors; Epithelial Cells; Filaricides; Haplorhini; HEK293 Cells; Humans; Ionophores; Larva; Molecular Structure; Molting; Onchocerca volvulus; Onchocerciasis; Onchocerciasis, Ocular; Protons; Salicylanilides; Structure-Activity Relationship	2011
Dual protonophore-chitinase inhibitors dramatically affect O. volvulus molting. Journal of medicinal chemistry, 2014, Jul-10, Volume: 57, Issue:13 Topics: Animals; Antinematodal Agents; Caenorhabditis elegans; Chitinases; Enzyme Inhibitors; Ionophores; Molting; Onchocerca volvulus; Onchocerciasis; Salicylanilides; Structure-Activity Relationship; Uncoupling Agents	2014
Repositioning of an existing drug for the neglected tropical disease Onchocerciasis. Proceedings of the National Academy of Sciences of the United States of America, 2010, Feb-23, Volume: 107, Issue:8 Topics: Animals; Anthelmintics; Chitin; Chitinases; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Molting; Onchocerca; Onchocerciasis; Salicylanilides; Small Molecule Libraries	2010
A computational analysis of the binding mode of closantel as inhibitor of the Onchocerca volvulus chitinase: insights on macrofilaricidal drug design. Journal of computer-aided molecular design, 2011, Volume: 25, Issue:12 Topics: Amino Acid Sequence; Animals; Anthelmintics; Chitinases; Crystallography, X-Ray; Drug Design; Humans; Molecular Dynamics Simulation; Molecular Sequence Data; Onchocerca volvulus; Onchocerciasis; Protein Binding; Salicylanilides; Thermodynamics	2011