Page last updated: 2024-10-31

clorgyline and Pregnancy

clorgyline has been researched along with Pregnancy in 20 studies

Clorgyline: An antidepressive agent and monoamine oxidase inhibitor related to PARGYLINE.
clorgyline : An aromatic ether that is the 2,4-dichlorophenyl ether of 3-aminopropan-1-ol in which the nitrogen is substituted by a methyl group and a prop-1-yn-3-yl group. A monoamine oxidase inhibitor, it was formerly used as an antidepressant.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"We have evaluated the impact of chronic administration of clorgyline, a potent monoamine oxidase A inhibitor and a former antidepressant, on the preimplantation embryo development in Wistar rats."1.37Relationship between serotonin and norepinephrine levels and the preimplantation embryo development in rat. ( Ferenc, P; Hodorova, I; Marekova, M; Maslankova, J; Mihalik, J; Rybarova, S, 2011)
"We have evaluated the impact of chronic administration of clorgyline, a potent monoamine oxidase A inhibitor and a former antidepressant, on the preimplantation embryo development in Wistar rats."1.36Impact of 2 doses of clorgyline on the rat preimplantation embryo development and the monoamine levels in urine. ( Ferenc, P; Hodorová, I; Kušnír, J; Mareková, M; Mašlanková, J; Mihalik, J; Rybárová, S; Schmidtová, K; Špakovská, T, 2010)
"Clorgyline treatments from E15 to P7 or from P0 to P7 disrupted the formation of barrels in the anterior snout representation and in parts of the posteromedial barrel subfield (PMBSF)."1.30Effects of monoamine oxidase A inhibition on barrel formation in the mouse somatosensory cortex: determination of a sensitive developmental period. ( Callebert, J; Cases, O; Gaspar, P; Launay, JM; Price, DJ; Seif, I; Vitalis, T, 1998)
"[3H]Pargyline has been covalently linked to active sites of both type A and type B monoamine oxidase (MAO) obtained from various tissues."1.26Studies on the pargyline-binding site of different types of monoamine oxidase. ( Yu, PH, 1981)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199013 (65.00)18.7374
1990's3 (15.00)18.2507
2000's2 (10.00)29.6817
2010's2 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cao, X1
Rui, L1
Pennington, PR1
Chlan-Fourney, J1
Jiang, Z1
Wei, Z1
Li, XM1
Edmondson, DE1
Mousseau, DD1
Lewinsohn, R2
Glover, V1
Sandler, M1
Mihalik, J2
Mašlanková, J2
Špakovská, T1
Mareková, M2
Hodorová, I2
Kušnír, J1
Rybárová, S2
Ferenc, P2
Schmidtová, K1
Franke, RM1
Belluzzi, JD1
Leslie, FM1
Sodha, RJ1
Proegler, M1
Schneider, H1
Yu, PH1
Emerole, GO1
Castro Costa, MR1
Edelstein, SB1
Castiglione, CM1
Chao, H1
Breakefield, XO1
Whitaker-Azmitia, PM1
Zhang, X1
Clarke, C1
Gu, XF1
Azmitia, EC1
Vitalis, T1
Cases, O1
Callebert, J1
Launay, JM1
Price, DJ1
Seif, I1
Gaspar, P1
Chordikian, FJ1
Tabakoff, B1
Alivisatos, SG1
Szutowicz, A1
Tomaszewicz, M1
Orsulak, PJ1
Yoshimoto, Y1
Sakumoto, T1
Aono, T1
Kimura, H1
Maeda, T1
Tanizawa, O1
Naoi, M1
Nagatsu, T1
Tipton, KF1
McCrodden, JM1
Youdim, MB1
Pekkel', VA1
Kirkel', AZ1
Weyler, W1
Salach, JI1

Reviews

1 review available for clorgyline and Pregnancy

ArticleYear
Mammalian monoamine-oxidizing enzymes, with special reference to benzylamine oxidase in human tissues.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1984, Volume: 17, Issue:3-4

    Topics: Adult; Animals; Benzylamine Oxidase; Cattle; Cells, Cultured; Child; Clorgyline; Dogs; Female; Fetus

1984

Other Studies

19 other studies available for clorgyline and Pregnancy

ArticleYear
Serine 209 resides within a putative p38(MAPK) consensus motif and regulates monoamine oxidase-A activity.
    Journal of neurochemistry, 2009, Volume: 111, Issue:1

    Topics: Analysis of Variance; Animals; Benzimidazoles; Calcium; Carbocyanines; Cell Survival; Cells, Culture

2009
Beta-phenylethylamine and benzylamine as substrates for human monoamine oxidase A: A source of some anomalies?
    Biochemical pharmacology, 1980, Mar-01, Volume: 29, Issue:5

    Topics: Benzylamines; Clorgyline; Deamination; Enzyme Inhibitors; Female; Humans; Kinetics; Monoamine Oxidas

1980
Impact of 2 doses of clorgyline on the rat preimplantation embryo development and the monoamine levels in urine.
    Reproductive sciences (Thousand Oaks, Calif.), 2010, Volume: 17, Issue:8

    Topics: Animals; Antidepressive Agents; Biogenic Monoamines; Blastocyst; Clorgyline; Dose-Response Relations

2010
Relationship between serotonin and norepinephrine levels and the preimplantation embryo development in rat.
    Bratislavske lekarske listy, 2011, Volume: 112, Issue:2

    Topics: Animals; Clorgyline; Embryonic Development; Female; Monoamine Oxidase Inhibitors; Norepinephrine; Pr

2011
Gestational exposure to nicotine and monoamine oxidase inhibitors influences cocaine-induced locomotion in adolescent rats.
    Psychopharmacology, 2007, Volume: 195, Issue:1

    Topics: Age Factors; Animals; Animals, Newborn; Behavior, Animal; Clorgyline; Cocaine; Dose-Response Relatio

2007
Transfer and metabolism of norepinephrine studied from maternal-to-fetal and fetal-to-maternal sides in the in vitro perfused human placental lobe.
    American journal of obstetrics and gynecology, 1984, Feb-15, Volume: 148, Issue:4

    Topics: Antipyrine; Clorgyline; Female; Glucose; Humans; In Vitro Techniques; Lactates; Lactic Acid; Mandeli

1984
Studies on the pargyline-binding site of different types of monoamine oxidase.
    Canadian journal of biochemistry, 1981, Volume: 59, Issue:1

    Topics: Amino Acid Sequence; Animals; Binding Sites; Cattle; Clorgyline; Female; Humans; In Vitro Techniques

1981
Benzylamine oxidase activity in rat embryo and placenta at organogenesis.
    Enzyme, 1982, Volume: 28, Issue:4

    Topics: Animals; Benzylamine Oxidase; Clorgyline; Embryo, Mammalian; Female; Gestational Age; Monoamine Oxid

1982
Properties of monoamine oxidase in control and Lesch-Nyhan fibroblasts.
    Biochemical genetics, 1980, Volume: 18, Issue:5-6

    Topics: Adolescent; Adult; Age Factors; Cells, Cultured; Child; Child, Preschool; Clorgyline; Female; Fibrob

1980
Effects of gestational exposure to monoamine oxidase inhibitors in rats: preliminary behavioral and neurochemical studies.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1994, Volume: 11, Issue:2

    Topics: Animals; Anxiety; Avoidance Learning; Behavior, Animal; Brain; Brain Chemistry; Catalepsy; Clorgylin

1994
Integrative transporter-mediated release from cytoplasmic and vesicular 5-hydroxytryptamine stores in cultured neurons.
    European journal of pharmacology, 1993, Apr-22, Volume: 235, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain Stem; Carrier Proteins; Cells, Cultured; Clorgyline; F

1993
Effects of monoamine oxidase A inhibition on barrel formation in the mouse somatosensory cortex: determination of a sensitive developmental period.
    The Journal of comparative neurology, 1998, Apr-06, Volume: 393, Issue:2

    Topics: Animals; Axons; Behavior, Animal; Clorgyline; Dose-Response Relationship, Drug; Embryonic and Fetal

1998
Ontogeny of multiple forms of monoamine oxidase in mouse brain.
    Brain research, 1975, Aug-08, Volume: 93, Issue:2

    Topics: Age Factors; Animals; Animals, Newborn; Body Weight; Brain; Clorgyline; Female; Fetus; Gestational A

1975
Modification of substrate-inhibitor affinities of human platelet monoamine oxidase B in vitro.
    The Journal of biological chemistry, 1989, Oct-25, Volume: 264, Issue:30

    Topics: Antibodies; Antigen-Antibody Complex; Benzylamines; Blood Platelets; Clorgyline; Female; Humans; Int

1989
Histochemical studies on human placental and chorionic monoamine oxidase.
    Obstetrics and gynecology, 1986, Volume: 67, Issue:3

    Topics: Chorion; Chorionic Villi; Clorgyline; Female; Gestational Age; Histocytochemistry; Humans; Monoamine

1986
Inhibition of monoamine oxidase by 3,4-dihydroxyphenylserine.
    Journal of neurochemistry, 1986, Volume: 47, Issue:2

    Topics: Clorgyline; Droxidopa; Female; Humans; Kinetics; Mitochondria; Mitochondria, Liver; Monoamine Oxidas

1986
Oxidation and enzyme-activated irreversible inhibition of rat liver monoamine oxidase-B by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
    The Biochemical journal, 1986, Dec-01, Volume: 240, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Clorgyline; Female; Half-Life; Isoenzymes; Ki

1986
[Unusual inhibition of monoamine oxidase activity induced by clorgyline].
    Biokhimiia (Moscow, Russia), 1988, Volume: 53, Issue:7

    Topics: Clorgyline; Female; Flavin-Adenine Dinucleotide; Humans; In Vitro Techniques; Isoenzymes; Models, Bi

1988
Purification and properties of mitochondrial monoamine oxidase type A from human placenta.
    The Journal of biological chemistry, 1985, Oct-25, Volume: 260, Issue:24

    Topics: 2,2'-Dipyridyl; Amphetamine; Animals; Cattle; Chromatography; Clorgyline; Disulfides; Electrophoresi

1985