clorgyline has been researched along with Insulinoma in 2 studies
Clorgyline: An antidepressive agent and monoamine oxidase inhibitor related to PARGYLINE.
clorgyline : An aromatic ether that is the 2,4-dichlorophenyl ether of 3-aminopropan-1-ol in which the nitrogen is substituted by a methyl group and a prop-1-yn-3-yl group. A monoamine oxidase inhibitor, it was formerly used as an antidepressant.
Insulinoma: A benign tumor of the PANCREATIC BETA CELLS. Insulinoma secretes excess INSULIN resulting in HYPOGLYCEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect on insulin release of efaroxan, an alpha 2-adrenoceptor antagonist and a highly potent drug at imidazoline I1 receptors, and the effects of seven other imidazoline compounds selective for the imidazoline I1 or I2 receptors, were studied in the rat insulinoma cell line RIN-5AH." | 3.69 | Imidazolines stimulate release of insulin from RIN-5AH cells independently from imidazoline I1 and I2 receptors. ( Haque, M; Kulkarni, RN; MacDermot, J; Olmos, G, 1994) |
| "Both islet and insulinoma are more sensitive to inhibition by pargyline than clorgyline." | 1.27 | Comparison of monoamine oxidase in golden hamster islets and insulinoma. ( Castleberry, CA; Feldman, JM; Seigler, HF; Vervaert, C, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Feldman, JM | 1 |
| Castleberry, CA | 1 |
| Vervaert, C | 1 |
| Seigler, HF | 1 |
| Olmos, G | 1 |
| Kulkarni, RN | 1 |
| Haque, M | 1 |
| MacDermot, J | 1 |
2 other studies available for clorgyline and Insulinoma
| Article | Year |
|---|---|
Comparison of monoamine oxidase in golden hamster islets and insulinoma.
Topics: Adenoma, Islet Cell; Animals; Clorgyline; Cricetinae; Insulinoma; Islets of Langerhans; Kinetics; Me | 1983 |
Imidazolines stimulate release of insulin from RIN-5AH cells independently from imidazoline I1 and I2 receptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Affinity Labels; | 1994 |