clorgyline has been researched along with Hyperactivity, Motor in 3 studies
Clorgyline: An antidepressive agent and monoamine oxidase inhibitor related to PARGYLINE.
clorgyline : An aromatic ether that is the 2,4-dichlorophenyl ether of 3-aminopropan-1-ol in which the nitrogen is substituted by a methyl group and a prop-1-yn-3-yl group. A monoamine oxidase inhibitor, it was formerly used as an antidepressant.
| Excerpt | Relevance | Reference |
|---|---|---|
| " High doses of clorgyline, a selective inhibitor MAO-A, produced a characteristic stereotyped syndrome of hypermotility and tremor as well as an increase in apparent 5-HT and a decrease in apparent 5-HIAA in brain." | 3.65 | The inhibition of A and B forms of MAO in the production of a characteristic behabioural syndrome in rats after 1-tryptophan loading. ( Lassen, JB; Squires, RF, 1975) |
| "Clorgyline pretreatment, both single and repeated, altered the effects of single METH challenges on apparent 5-hydroxytryptamine (serotonin) turnover in the region of the striatum and accumbens." | 1.33 | Inhibition of methamphetamine-induced hyperlocomotion in mice by clorgyline, a monoamine oxidase-a inhibitor, through alteration of the 5-hydroxytriptamine turnover in the striatum. ( Kitanaka, J; Kitanaka, N; Takemura, M, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Halberstadt, AL | 1 |
| Buell, MR | 1 |
| Masten, VL | 1 |
| Risbrough, VB | 1 |
| Geyer, MA | 1 |
| Kitanaka, N | 1 |
| Kitanaka, J | 1 |
| Takemura, M | 1 |
| Squires, RF | 1 |
| Lassen, JB | 1 |
3 other studies available for clorgyline and Hyperactivity, Motor
| Article | Year |
|---|---|
Modification of the effects of 5-methoxy-N,N-dimethyltryptamine on exploratory behavior in rats by monoamine oxidase inhibitors.
Topics: Animals; Behavior, Animal; Behavioral Research; Clorgyline; DOM 2,5-Dimethoxy-4-Methylamphetamine; D | 2008 |
Inhibition of methamphetamine-induced hyperlocomotion in mice by clorgyline, a monoamine oxidase-a inhibitor, through alteration of the 5-hydroxytriptamine turnover in the striatum.
Topics: Animals; Clorgyline; Corpus Striatum; Dose-Response Relationship, Drug; Drug Administration Schedule | 2005 |
The inhibition of A and B forms of MAO in the production of a characteristic behabioural syndrome in rats after 1-tryptophan loading.
Topics: Alkynes; Animals; Brain Chemistry; Clorgyline; Drug Synergism; Humans; Hydroxyindoleacetic Acid; Hyp | 1975 |