Page last updated: 2024-10-31

clorgyline and Aging

clorgyline has been researched along with Aging in 22 studies

Clorgyline: An antidepressive agent and monoamine oxidase inhibitor related to PARGYLINE.
clorgyline : An aromatic ether that is the 2,4-dichlorophenyl ether of 3-aminopropan-1-ol in which the nitrogen is substituted by a methyl group and a prop-1-yn-3-yl group. A monoamine oxidase inhibitor, it was formerly used as an antidepressant.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-199017 (77.27)18.7374
1990's3 (13.64)18.2507
2000's2 (9.09)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Maurel, A1
Hernandez, C1
Kunduzova, O1
Bompart, G1
Cambon, C1
Parini, A1
Francés, B1
Tranquilli Leali, FM1
Artico, M1
Potenza, S1
Cavallotti, C1
Lam, DM1
Fung, SC1
Kong, YC1
Hall, TR1
Urueña, G1
Cao Danh, H2
Strolin Benedetti, M2
Dostert, P1
Mousset, A2
Fowler, CJ3
Benedetti, MS1
Knoll, J1
Yen, TT1
Dallo, J1
Oreland, L1
Marcusson, J1
Winblad, B1
Leung, TK1
Lai, JC1
Lim, L1
Barrand, MA1
Callingham, BA5
Finnegan, KT1
Irwin, I1
Delanney, LE1
Langston, JW1
Houslay, MD1
Palmer, RW1
Duncan, RJ1
Lyles, GA3
Oxenkrug, GF1
McIntyre, IM1
Requintina, PJ1
Duffy, JD1
Wagner, GC1
Walsh, SL1
Pasquier-Béchet, P1
Meco, M1
Bonifati, V1
Collier, WL1
Ramacci, MT1
Amenta, F1
Kalaria, RN1
Harik, SI1
Arai, Y1
Kinemuchi, H1

Other Studies

22 other studies available for clorgyline and Aging

ArticleYear
Age-dependent increase in hydrogen peroxide production by cardiac monoamine oxidase A in rats.
    American journal of physiology. Heart and circulatory physiology, 2003, Volume: 284, Issue:4

    Topics: Aging; Animals; Blotting, Western; Cell Membrane; Clorgyline; Hydrogen Peroxide; Kinetics; Luminesce

2003
Age-related changes of monoaminooxidases in rat cerebellar cortex.
    European journal of histochemistry : EJH, 2003, Volume: 47, Issue:1

    Topics: Aging; Animals; Cerebellum; Clorgyline; Enzyme Inhibitors; Monoamine Oxidase; Monoamine Oxidase Inhi

2003
Postnatal development of dopaminergic neurons in the rabbit retina.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1981, Volume: 1, Issue:10

    Topics: Aging; Animals; Animals, Newborn; Benzylamines; Clorgyline; Dopamine; Kinetics; Monoamine Oxidase; N

1981
Distribution of monoamine oxidase activity in tissues of the urodeles Ambystoma tigrinum (tiger salamander) and Necturus maculosus (mudpuppy).
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1983, Volume: 74, Issue:1

    Topics: Aging; Ambystoma; Animals; Brain; Clorgyline; Female; Intestines; Liver; Male; Monoamine Oxidase; Ne

1983
Age-related changes in benzylamine oxidase activity in rat tissues.
    The Journal of pharmacy and pharmacology, 1984, Volume: 36, Issue:9

    Topics: Aging; Animals; Benzylamine Oxidase; Clorgyline; Kinetics; Male; Monoamine Oxidase; Proteins; Rats;

1984
The metabolism of dopamine by both forms of monoamine oxidase in the rat brain and its inhibition by cimoxatone.
    Journal of neurochemistry, 1983, Volume: 40, Issue:6

    Topics: Aging; Animals; Brain; Clorgyline; Dopamine; Isoenzymes; Kinetics; Male; Monoamine Oxidase; Monoamin

1983
Long-lasting, true aphrodisiac effect of (-)-deprenyl in sexually sluggish old male rats.
    Modern problems of pharmacopsychiatry, 1983, Volume: 19

    Topics: Aging; Amphetamine; Animals; Aphrodisiacs; Castration; Clorgyline; Copulation; Male; Phenethylamines

1983
Titration of human brain monoamine oxidase -A and -B by clorgyline and L-deprenil.
    Naunyn-Schmiedeberg's archives of pharmacology, 1980, Volume: 311, Issue:3

    Topics: Adult; Aged; Aging; Benzylamines; Brain; Cerebral Cortex; Child, Preschool; Clorgyline; Humans; In V

1980
The regional distribution of monoamine oxidase activities towards different substrates: effects in rat brain of chronic administration of manganese chloride and of ageing.
    Journal of neurochemistry, 1981, Volume: 36, Issue:6

    Topics: Aging; Animals; Benzylamines; Brain; Chlorides; Clorgyline; Dopamine; Female; Male; Manganese; Manga

1981
Monoamine oxidase activities in brown adipose tissue of the rat: some properties and subcellular distribution.
    Biochemical pharmacology, 1982, Jun-15, Volume: 31, Issue:12

    Topics: Adipose Tissue, Brown; Aging; Animals; Clorgyline; Kinetics; Male; Microsomes; Mitochondria; Monoami

1982
Age-dependent effects of the 2'-methyl analog of 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine: prevention by inhibitors of monoamine oxidase B.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 273, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Aging; Animals; Clorgyline; Corpus Striatum; Dopamine;

1995
The action of the local anaesthetic, benzyl alcohol and the monoamine oxidase inhibitor, clorgyline on the beta-hydroxybutyrate dehydrogenase activity of adult and weanling rat brain mitochondria.
    The Journal of pharmacy and pharmacology, 1978, Volume: 30, Issue:11

    Topics: Aging; Anesthetics, Local; Animals; Benzyl Alcohols; Benzyl Compounds; Brain; Clorgyline; Hydroxybut

1978
Selective influences of age and thyroid hormones on type A monoamine oxidase of the rat heart.
    The Journal of pharmacy and pharmacology, 1979, Volume: 31, Issue:11

    Topics: Aging; Animals; Clorgyline; Heart; In Vitro Techniques; Monoamine Oxidase; Myocardium; Organ Size; R

1979
Evidence for a clorgyline-resistant monoamine metabolizing activity in the rat heart.
    The Journal of pharmacy and pharmacology, 1975, Volume: 27, Issue:9

    Topics: Aging; Animals; Benzylamines; Biogenic Amines; Clorgyline; Drug Resistance; In Vitro Techniques; Kin

1975
The effect of age on the number of monoamine oxidase active centres in the rat heart.
    Biochemical Society transactions, 1978, Volume: 6, Issue:5

    Topics: Aging; Animals; Clorgyline; Dose-Response Relationship, Drug; Male; Mitochondria, Heart; Monoamine O

1978
Proceedings: Changes in the MAO activity with age in the rat vas deferens.
    British journal of pharmacology, 1975, Volume: 55, Issue:2

    Topics: Aging; Animals; Clorgyline; Male; Monoamine Oxidase; Organ Size; Rats; Vas Deferens

1975
The response of the pineal melatonin biosynthesis to the selective MAO-A inhibitor, clorgyline, in young and middle-aged rats.
    Progress in neuro-psychopharmacology & biological psychiatry, 1991, Volume: 15, Issue:6

    Topics: Aging; Animals; Clorgyline; Hydroxyindoleacetic Acid; Light; Male; Melatonin; Pineal Gland; Rats; Ra

1991
Evaluation of the effects of inhibition of monoamine oxidase and senescence on methamphetamine-induced neuronal damage.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 1991, Volume: 9, Issue:2

    Topics: Aging; Animals; Clorgyline; Corpus Striatum; Dopamine; Male; Methamphetamine; Mice; Monoamine Oxidas

1991
Age-related changes in the activities of the amine metabolizing enzymes of rat eye.
    The Journal of pharmacy and pharmacology, 1985, Volume: 37, Issue:5

    Topics: Aging; Alcohol Oxidoreductases; Amine Oxidase (Copper-Containing); Amines; Animals; Benzylamine Oxid

1985
Enzyme histochemistry of monoamine oxidase in the heart of aged rats.
    Mechanisms of ageing and development, 1987, Volume: 38, Issue:2

    Topics: Aging; Animals; Clorgyline; Heart; Histocytochemistry; Male; Monoamine Oxidase; Myocardium; Rats; Ra

1987
Differential postnatal development of monoamine oxidases A and B in the blood-brain barrier of the rat.
    Journal of neurochemistry, 1987, Volume: 49, Issue:5

    Topics: Aging; Animals; Benzylamines; Blood-Brain Barrier; Brain; Cerebral Cortex; Clorgyline; Microcirculat

1987
Differences between monoamine oxidase concentrations in striatum and forebrain of aged and young rats.
    Journal of neural transmission, 1988, Volume: 72, Issue:2

    Topics: Aging; Animals; Benzylamines; Clorgyline; Corpus Striatum; Frontal Lobe; Kinetics; Male; Monoamine O

1988