clopidogrel and Coronary Artery Disease

clopidogrel has been researched along with Coronary Artery Disease in 986 studies

Research

Studies (986)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (0.20)18.2507
2000's279 (28.30)29.6817
2010's602 (61.05)24.3611
2020's103 (10.45)2.80

Authors

AuthorsStudies
Benit, E; Diletti, R; Ferrario, M; Hamm, C; Heg, D; Huber, K; Janssens, L; Jüni, P; Mc Fadden, EP; Odutayo, A; Onuma, Y; Räber, L; Serruys, PW; Steg, PG; Valgimigli, M; Vranckx, P; Windecker, S1
Bressi, E; Capuano, M; Cavallari, I; Colaiori, I; Di Sciascio, G; Grigioni, F; Mangiacapra, F; Ricottini, E; Spoto, S; Sticchi, A; Ussia, GP; Viscusi, MM1
Amano, T; Ikari, Y; Inohara, T; Ishii, H; Kohsaka, S; Nishida, H; Noma, S; Shimoji, K; Tanaka, N; Ueno, K; Yamaji, K; Yashima, F1
Chen, XP; Du, YX; Hu, XL; Li, H; Li, MP; Li, MY; Liu, YL; Ma, QL; Peng, LM; Song, MY; Song, PY1
Contreras Bravo, NC; Corredor-Orlandelli, D; Fonseca Mendoza, DJ; Leal, MF; León-Torres, J; Mantilla-García, S; Mendoza-Ayús, SD; Ortega-Recalde, O; Pardo-Oviedo, JM; Parra Abaunza, K; Peña, LC; Rodríguez-Carrillo, J; Sambracos-Parrado, S; Tovar-Tirado, J; Vega-Ramírez, V1
Martínez-Quintana, E; Medina-Gil, JM; Rodríguez-González, F; Saavedra-Santana, P; Santana-Mateos, M; Tugores, A1
De Luca, L; Ferraro, PM; Gabrielli, D; Grigioni, F; Mangiacapra, F; Mangiacapra, R; Melfi, R; Nusca, A; Paolucci, L; Ussia, GP; Viscusi, MM1
Barry, HC1
Akimaru, K; Arima, H; Higa, N; Ikemiyagi, H; Ishida, A; Iwabuchi, M; Kakazu, M; Maeda, T; Miyagi, A; Ohya, Y; Shiohira, S; Shiohira, T; Tokashiki, S; Toma, Y; Uehara, H; Wake, M; Wakugawa, H; Zaima, S1
Alraies, MC; Cuisset, T; Faisaluddin, M; Fischman, DL; Khalil, F; Pasha, AK; Rao, SV; Sabouret, P; Sandhyavenu, H; Savage, MP; Ullah, W; Zahid, S1
Gong, Y; Han, Y; Jiang, H; Kang, Y; Lai, X; Li, J; Li, Y; Liu, B; Liu, Y; Ma, S; Qi, Z; Ren, L; Sun, H; Tang, C; Tang, Y; Zhao, X; Zheng, M1
Circhetta, S; De Luca, R; Grigioni, F; Mangiacapra, F; Melfi, R; Nusca, A; Paolucci, L; Ricottini, E; Ussia, GP; Viscusi, MM1
Ben-Yehuda, O; Brodie, BR; Kirtane, AJ; Liu, M; Mehran, R; Metzger, DC; Musikantow, DR; Redfors, B; Rinaldi, MJ; Stone, GW; Stuckey, TD; Weisz, G; Witzenbichler, B1
Ahn, CM; Cho, JY; Choi, D; Hong, MK; Hong, SJ; Jang, Y; Kim, BK; Kim, JS; Ko, YG; Lee, SJ; Lee, YJ; Yun, KH1
Ahn, SG; Chang, K; Cho, JR; Her, AY; Jeong, YH; Joo, HJ; Kim, BK; Kim, HS; Kim, MH; Lee, SY; Lim, DS; Park, Y; Shin, ES; Song, YB; Suh, JW1
Agewall, S; Hasegawa, K; Komiyama, M1
Dou, KF; Gao, R; Guan, C; Huang, Y; Qiao, S; Wang, HY; Wu, Y; Xie, L; Xu, B; Yang, W; Yang, Y; Zhang, R1
Agewall, S; Barton, JC; Drexel, H; Hasegawa, K; Kaski, JC; Kimura, T; Komiyama, M; Lewis, BS; Tamargo, J; Yamamoto, K1
Al-Sayaghi, KM; Albadrani, MS; Alotaibi, YA; Elhusein, AM; Fadlalmola, HA; Hussein, MK; Mamanao, DM; Masada, HK; Mohamedsalih, WE1
Chen, Y; Gao, H; Han, P; Li, C; Lian, K; Liang, Y; Liu, Y; Tan, Z; Tao, F; Wang, Q; Wang, Z; Xu, S; Yang, L; Zhang, A; Zhang, Y; Zhao, S; Zhu, B1
Angiolillo, DJ; Been, L; Franchi, F; Galli, M; Rollini, F; Zenni, MM1
Dookeeram, D; Giddings, S; Gomes, C; Grimaldos, G; Grimaldos, K; Ishmael, A; Kampradi, L; Peram, L; Ramlackhansingh, A; Raza, S; Richard, S; Sandy, S; Schneider, D; Seecheran, NA; Seecheran, R; Seecheran, V; Sukha, D; Tello-Montoliu, A; Umaharan, P1
Han, K; Huang, X; Ma, M; Sun, T; Yang, S; Zhao, Z; Zhou, Y1
Ben-Yehuda, O; Brodie, BR; Cox, DA; Duffy, PL; Henry, TD; Kirtane, AJ; Liu, M; Madhavan, MV; Mazzaferri, EL; Mehran, R; Metzger, DC; Neumann, FJ; Redfors, B; Rinaldi, MJ; Shahim, B; Srdanovic, I; Stone, GW; Stuckey, TD; Weisz, G; Witzenbichler, B; Zhou, Z1
Banach, M; Biondi-Zoccai, G; Costabel, JP; De Rosa, S; Fischman, D; Galli, M; Gulati, M; Sabouret, P; Savage, MP; Spadafora, L; Ullah, W; Zeitouni, M1
Aboyans, V; Angiolillo, D; Atar, D; Capodanno, D; Fox, KAA; Halvorsen, S; James, S; Jüni, P; Kunadian, V; Landi, A; Leonardi, S; Mehran, R; Montalescot, G; Navarese, EP; Niebauer, J; Oliva, A; Piccolo, R; Price, S; Storey, RF; Valgimigli, M; Völler, H; Vranckx, P; Windecker, S1
Baruś, P; Filipiak, KJ; Grabowski, M; Gumiężna, K; Klimczak-Tomaniak, D; Kochman, J; Kuca-Warnawin, E; Ochijewicz, D; Opolski, G; Pasierb, K; Sygitowicz, G; Tomaniak, M; Wiśniewska, A1
Gong, Y; Li, J; Wang, X; Wang, Y; Zhou, T1
Bae, JH; Bailey, K; Baudhuin, LM; Bell, MR; Farkouh, ME; Fu, YP; Geller, N; Goodman, SG; Hasan, A; Ingraham, BS; Iturriaga, E; Jeong, MH; Lennon, RJ; Lerman, A; Mathew, V; Pereira, NL; Rihal, C; Rosenberg, Y; So, D; Tanguay, JF; Welsh, RC1
Chen, X; Hu, X; Li, H; Li, M; Ma, Q; Peng, L; Song, P; Tang, J; Zhang, Y; Zhou, G1
Ahn, SG; Chang, K; Cho, JR; Her, AY; Jeong, YH; Joo, HJ; Kim, BK; Kim, HS; Kim, MH; Kim, SJ; Lee, SY; Lim, DS; Park, Y; Shin, ES; Song, YB; Suh, JW1
Esposito, G; Piccolo, R; Simonetti, F; Spaccarotella, C1
Wang, B; Wang, M; Xu, Y; Yan, M; Yu, S1
Farley, JF; Kumar, A; Lutsey, PL; Rajpurohit, A; Schommer, JC; St Peter, WL; Van't Hof, JR1
Berdibekov, BS; Bulaeva, NI; Golukhova, EZ; Kubova, MC; Ruzina, EV1
Cai, Y; Chen, Z; He, Y; Li, C; Zhang, J1
Agarwal, M; Angiolillo, DJ; Bass, TA; Been, L; Briceno, M; Franchi, F; Garcia, E; Kairouz, V; Kureti, M; Moon, JY; Nagaraju, D; Rivas Rios, J; Rivas, A; Rollini, F; Soffer, D; Suryadevara, S; Wali, M; Yaranov, D; Zenni, MM1
Gorog, DA1
Alexopoulos, D; Altman, RB; Aradi, D; Backman, JD; Bergmeijer, TO; Bliden, KP; Campo, G; Chang, K; Cleator, JH; Déry, JP; Dridi, NP; Fernandez-Cadenas, I; Fontana, P; Gawaz, M; Geisler, T; Gensini, GF; Giusti, B; Gong, L; Gurbel, PA; Hochholzer, W; Holmvang, L; Kim, EY; Kim, HS; Klein, TE; Kubo, M; Lee, MTM; Lewis, JP; Marcucci, R; Mitchell, BD; Montaner, J; Pakyz, RE; Reny, JL; Ritchie, MD; Roden, DM; Ryan, K; Schaeffeler, E; Schwab, M; Shin, JG; Shuldiner, AR; Siller-Matula, JM; Ten Berg, JM; Trenk, D; Valgimigli, M; Wen, MS; Whaley, RM; Winter, S1
Ajisaka, H; Fukumoto, Y; Harada, A; Hirakawa, Y; Ishimatsu, T; Ishizaki, Y; Kagiyama, K; Kakuma, T; Katsuki, Y; Kawasaki, T; Murasato, Y; Sasaki, KI; Shimamatsu, J; Tashiro, H; Ueno, T; Yokoi, H1
Wang, P; Wang, XZ; Yao, Y; Zhang, L; Zhao, W; Zhao, X; Zhou, TN1
Doukas, D; Schimmer, H; Zehtabchi, S1
Ceriello, A; Di Sciascio, G; Grigioni, F; Manfrini, S; Melfi, R; Nicolucci, A; Nusca, A; Pozzilli, P; Proscia, C; Tuccinardi, D; Ussia, GP1
Ali, ZA; Baber, U; Ben-Yehuda, O; Brodie, BR; Chen, S; Cox, DA; Duffy, PL; Henry, TD; Kirtane, AJ; Mazzaferri, EL; Mehran, R; Metzger, DC; Neumann, FJ; Redfors, B; Rinaldi, MJ; Rubin, GA; Stone, GW; Stuckey, TD; Weisz, G; Witzenbichler, B; Zhang, Y1
Barbato, E; Bressi, E; Capuano, M; Cavallari, I; Colaiori, I; Di Sciascio, G; Mangiacapra, F; Ricottini, E; Spoto, S; Viscusi, MM1
Ahn, CM; Cho, S; Choi, D; Choi, SH; Gwon, HC; Hahn, JY; Hong, MK; Hong, SJ; Jang, Y; Kang, TS; Kim, BK; Kim, JS; Ko, YG; Shin, DH; Song, YB1
Ayari, A; Barra, N; Billé, J; Joly, P; Maillard, L; Peycher, P; Sévilla, J; Silvestri, M; Tavildari, A; Vochelet, F1
Bhatt, DL; Cannon, CP; de Veer, A; Hohnloser, SH; Jansky, P; Kleine, E; Lip, GYH; Nordaby, M; Oldgren, J; Seung, KB; Steg, PG; Ten Berg, JM; Zateyshchikov, DA1
Bhatt, DL; Cannon, CP; Hohnloser, SH; Kimura, T; Lip, GYH; Maeng, M; Miede, C; Nordaby, M; Oldgren, J; Steg, PG; Ten Berg, JM1
Brophy, DF; Guzman, LA; Martin, E; Puckett, L; Siddiqui, MS; Stravitz, T; Trankle, CR; Vo, C1
Chen, M; Zhang, L; Zhang, Z; Zhao, Q1
Bhatt, DL; Cannon, CP; de Veer, A; Hohnloser, SH; Kimura, T; Lip, GYH; Miede, C; Nordaby, M; Oldgren, J; Steg, PG; Ten Berg, JM1
Colombo, A; Gallo, F; Giannini, F; Khokhar, AA; Laricchia, A; Mangieri, A; Sticchi, A1
Bliden, K; Gurbel, PA; Rout, A; Tantry, US; Timilsina, S1
Alexopoulos, D; Andreadou, I; Dimitriadis, G; Ikonomidis, I; Katogiannis, K; Katsimaglis, G; Kousathana, F; Kyriakou, E; Lambadiari, V; Maratou, E; Papadopoulou, A; Parissis, J; Plotas, P; Stamatelopoulos, K; Taichert, M; Tsantes, AE; Tsoumani, M; Varlamos, C1
Aurigemma, C; Borovac, JA; Buffon, A; Burzotta, F; Canonico, F; Ceccarelli, I; Crea, F; D'Amario, D; Flex, A; Franceschi, F; Francese, F; Galli, M; Leone, AM; Limbruno, U; Migliaro, S; Montone, RA; Niccoli, G; Porto, I; Restivo, A; Tinelli, G; Trani, C; Vergallo, R1
Álvarez-Antón, S; Carballeira, D; Concepción, R; Dejuán-Bitriá, C; Del Castillo, H; Delgado-Calva, FA; López-Soberón, E; Marschall, A; Martí, D; Morales, MJ; Palazuelos, J; Pérez-Guzmán, J1
Cang, H; He, M; Li, J; Li, Y; Liu, G; Mu, H; Shi, J; Sun, D; Wang, J; Wang, W; Xu, M; Zhang, C; Zhang, H; Zhang, Z; Zhao, C; Zhao, S1
Chai, M; Liang, J; Liu, W; Liu, X; Xi, Z; Yu, Y; Zhao, Y; Zhou, Y1
Berry, NC; Bhatt, DL; Cannon, CP; Hohnloser, SH; Kimura, T; Lip, GYH; Mauri, L; Miede, C; Nordaby, M; Oldgren, J; Steg, PG; Ten Berg, JM1
Cao, J; Deng, XL; Fan, L; Huang, X; Li, JH; Liu, L; Wang, YM; Zou, X1
Ben-Dor, I; Chen, Y; Gajanana, D; Iantorno, M; Khalid, N; Khan, JM; Kolm, P; Musallam, A; Rogers, T; Satler, LF; Shlofmitz, E; Torguson, R; Waksman, R; Weintraub, WS; Zhang, C1
Katkat, F; Kum, G; Okuyan, E; Şahin, İ; Varol, S1
Gwak, HS; Lee, N; Seong, JM; Yoon, HY1
Amorim, MJ; Barros, AS; Cerqueira, RJ; Ferreira, AF; Leite-Moreira, AF; Lourenço, AP; Moreira, R; Pinho, P; Rocha-Gomes, JN; Saraiva, FA1
Alexopoulos, D; Altman, RB; Aradi, D; Backman, JD; Bergmeijer, TO; Bliden, K; Bradford, Y; Campo, G; Chang, K; Cleator, JH; Déry, JP; Dridi, NP; Fernandez-Cadenas, I; Fontana, P; Gawaz, M; Geisler, T; Gensini, GF; Giusti, B; Gong, L; Gurbel, PA; Hochholzer, W; Holmvang, L; Kim, EY; Kim, HS; Klein, TE; Kubo, M; Lee, MTM; Lewis, JP; Marcucci, R; Mitchell, BD; Montaner, J; Pakyz, RE; Reny, JL; Ritchie, MD; Roden, DM; Schaeffeler, E; Schwab, M; Shin, JG; Shuldiner, AR; Siller-Matula, JM; Ten Berg, JM; Trenk, D; Valgimigli, M; Verma, SS; Wallace, J; Wen, MS; Whaley, R; Winter, S1
Ahuja, N; Baker, MC; Robinson, WH; Rohatgi, N; Weng, Y1
Choi, WG; Kim, DW; Kim, GC; Kim, HY; Lee, CH1
Feng, W; Song, Y; Tiemuerniyazi, X; Xu, F; Yan, H1
Bao, S; Feng, J; Guo, X; Jia, L; Li, H; Sun, L; Wang, T; Yu, A; Yu, L; Zhao, T1
Bao, D; Han, X; Han, Y; Li, J; Li, Y; Li, Z; Liao, Z; Stone, GW; Wang, H; Wang, X; Xu, K1
Endo, H; Goto, I; Ishida, M; Itoh, T; Kimura, T; Koeda, Y; Kojima, T; Maegawa, Y; Morino, Y; Niiyama, M; Nishiyama, O; Osaki, T; Saitoh, H; Sakamoto, R; Sakamoto, T; Takahashi, F1
Abbott, JD; Bae, JH; Bailey, K; Baudhuin, L; Bell, M; Cagin, C; Chavez, I; Farkouh, ME; Fu, YP; Geller, N; Goodman, SG; Gordon, P; Hasan, A; Iturriaga, E; Jeong, MH; Lennon, R; Lerman, A; Mathew, V; Pereira, NL; Rihal, C; Rosenberg, Y; Sidhu, M; So, D; Tanguay, JF; Wang, L; Weinshilboum, R; Welsh, R1
Alsanjari, O; Hildick-Smith, D; Parker, J; Thomson, C; Trivedi, U1
Li, J; Ma, L; Yu, C; Yuan, Y; Zhao, J1
Angiolillo, DJ; Beitelshees, AL; Cavallari, LH; Chen, Y; Cook, KJ; Coons, JC; Dillon, C; Duarte, JD; Empey, PE; Franchi, F; Giri, J; Gong, Y; Johnson, JA; Kreutz, RP; Lee, CR; Lee, JC; Limdi, NA; McDonough, CW; Skaar, TC; Stevenson, JM; Stouffer, GA; Thomas, CD; Tuteja, S; Weck, KE1
Gao, R; Guo, T; Li, J; Li, Y; Qiao, S; Qiu, H; Tang, Y; Wang, Y; Xu, B; Yan, L; Yang, Y; Zheng, J2
Abdus, S; Gong, X; Gu, Q; Li, C; Shi, L; Tan, C; Wang, G; Wang, J; Yang, M1
Besteiro, A; Cequier, Á; Comin-Colet, J; Ferreiro, JL; Fuentes, L; Gómez-Hospital, JA; Gomez-Lara, J; Gracida, M; Lugo, LM; Marcano, AL; Romaguera, R; Roura, G; Sosa, SG; Teruel, L1
Adamson, PD; Loganath, K; Moss, AJ1
Bonaca, MP; De Luca, L; Magnani, G1
Camaj, A; Giustino, G; Halperin, JL; Miller, MS1
Biswas, M; Biswas, TK; Ibrahim, B; Rahaman, S2
Chen, XP; Du, YX; Li, MP; Ma, QL; Peng, LM; Song, PY; Zhu, KX1
Bhatt, DL; Cannon, CP; Costa, F; Hohnloser, SH; Lip, GYH; Miede, C; Nordaby, M; Oldgren, J; Steg, PG; Ten Berg, JM; Valgimigli, M1
Cai, ZX; Dou, KF; Song, WH; Wang, HY; Yang, YJ; Yin, D1
Bae, JW; Cho, BR; Cho, DK; Cho, JH; Choi, JH; Choi, JW; Choi, SH; Choi, WG; Chun, WJ; Gwon, HC; Hahn, JY; Im, ES; Jang, WJ; Jeong, JO; Koh, YY; Lee, JM; Lee, JY; Lee, SH; Lee, SU; Lee, SY; Lee, WS; Oh, JH; Oh, SK; Park, TK; Park, YH; Rha, SW; Song, YB; Yang, JH; Yoon, HJ; Yun, KH1
Jamali, HK; Khan, S; Kheiri, B; Osman, M; Saleem, M; Waqar, F1
Biswas, M; Kali, SK1
Chelidze, K; Mamatsashvili, I; Sikharulidze, I1
Deng, B; He, W; Lin, Y; Nie, R; Shu, X; Wang, J; Wu, X; Zhou, Z; Zhu, E1
Akao, M; Ako, J; Hagiwara, N; Hirayama, A; Kaikita, K; Kimura, K; Matoba, T; Matsui, K; Miyauchi, K; Nakamura, M; Ogawa, H; Yasuda, S1
Chen, R; Chen, X; Cheng, J; Hu, H; Hu, Y; Lin, S; Xu, X1
Fu, W; Hu, X; Jiang, H; Ma, R; Yang, J; Zhang, J1
Che, J; Chen, K; Dou, S; Liu, H; Liu, X; Wang, W; Wang, X; Zhang, X; Zhou, X1
Ahn, JH; Cho, SW; Choi, JH; Choi, KH; Choi, SH; Gwon, HC; Hahn, JY; Jang, YH; Kim, DY; Lee, JM; Lee, SH; Park, KT; Park, TK; Song, YB; Yang, JH1
Chen, S; Feng, W; Hu, S; Liu, S; Qu, J; Rao, C; Song, Y; Sun, H; Wang, L; Wang, S; Zhang, H; Zhao, Y; Zheng, Z1
Bae, JW; Cho, YH; Han, JK; Hur, SH; Jeon, DW; Kang, J; Kim, BS; Kim, HS; Kim, SH; Koo, BK; Lee, NH; Lim, SW; Park, KW; Park, TH; Rha, SW; Rhee, TM; Shin, ES; Won, KB; Yang, HM; Yoon, J1
Aziz, MA; Islam, MS; Jafrin, S; Naznin, NE; Reza, MS1
Abou Jaoude, P; Angiolillo, DJ; Bass, TA; Been, L; Briceno, M; Franchi, F; Jia, S; Lee, CH; Maaliki, N; Pineda, AM; Rivas, A; Rollini, F; Soffer, D; Suryadevara, S; Zenni, MM; Zhou, X1
Chen, X; Ji, L; Li, J; Su, J; Yang, J; Yu, Q; Zheng, N; Zhong, J1
Su, J; Xu, H; Xu, Z; Yang, J; Yu, Q; Zheng, N; Zhou, H1
Ariyoshi, N; Kitahara, H; Kobayashi, Y; Nishi, T; Ohno, Y; Saito, Y; Wakabayashi, S1
Aquila, G; Balla, C; Biscaglia, S; Campo, G; Cimaglia, P; Contoli, M; Del Franco, A; Ferrari, R; Fortini, F; Gallo, F; Pavasini, R; Pecoraro, A; Pestelli, G; Rizzo, P; Tonet, E; Vieceli Dalla Sega, F1
Bacchi-Reggiani, ML; Bordoni, B; Calabrò, P; Dallago, M; Di Pasquale, G; Franco, N; Leone, AM; Maggiolini, S; Magnavacchi, P; Mameli, S; Nicolino, A; Palmieri, C; Piccalò, G; Piovaccari, G; Rubboli, A; Saia, F; Sciahbasi, A; Steffanon, L; Vignali, L1
Dong, Y; He, H; Lu, J; Ma, X; Meng, T; Xie, J; Zhai, Y1
Amann, M; Bömicke, T; Hochholzer, W; Neumann, FJ; Stratz, C; Valina, CM1
Altman, DG; Benedetto, U; Flather, M; Gerry, S; Gray, A; Lees, B; Taggart, DP1
Bellomo, G; Carriero, A; Daffara, V; De Luca, G; Marino, P; Pergolini, P; Rolla, R; Verdoia, M1
Arima, Y; Hokimoto, S; Ishii, M; Ito, M; Iwashita, S; Kaikita, K; Kojima, S; Mitsuse, T; Oimatsu, Y; Sueta, D; Takahashi, A; Tsujita, K; Yamamoto, E1
Apruzzese, PK; Cutlip, DE; Kereiakes, DJ; Massaro, JM; Mauri, L; Secemsky, EA; Steg, PG; Yeh, RW1
Bhatt, DL; Grove, EL; Kristensen, SD; Pareek, M; Ten Berg, JM1
Aldazabal, A; Cerrato, E; Echavarría-Pinto, M; Escaned, J; Fernández-Ortiz, A; Gonzalo, N; Jimenez-Quevedo, P; Macaya, C; Mejia-Renteria, H; Nombela-Franco, L; Núñez-Gil, IJ; Quirós, A; Rumoroso, JR; Ryan, N; Salinas, P1
Ahn, JM; Choi, HI; Kang, SH; Kang, SJ; Kim, YH; Lee, CW; Lee, PH; Lee, SW; Park, DW; Park, SJ; Park, SW1
Bil, J; Bojko, K; Gil, RJ; Górny, J; Januszko-Giergielewicz, B; Kern, A; Sienkiewicz, E1
Gao, Y; He, J; Li, M; Li, Q; Luo, Y; Ren, X; Wu, C; Yu, X; Zhang, X; Zhang, Y1
Abnousi, F; Bhatt, DL; Deliargyris, EN; Desai, M; Ding, VY; Généreux, P; Gibson, CM; Hamm, CW; Harrington, RA; Mahaffey, KW; Prats, J; Price, MJ; Steg, PG; Stone, GW; Sundaram, V; White, HD; Yang, L; Yong, CM1
Gawrońska-Szklarz, B; Gorący, J; Jastrzębska, M; Kiedrowicz, R; Kornacewicz-Jach, Z; Olędzki, S; Safranow, K1
Ariotti, S; Baldo, A; Franzone, A; Gargiulo, G; Moschovitis, A; Piccolo, R; Santucci, A; Tumscitz, C; Valgimigli, M; Windecker, S1
Ako, J; Ando, K; Anzai, H; Hamasaki, T; Iijima, R; Inoue, K; Ishiwata, S; Ito, Y; Kadotani, M; Kawaguchi, K; Morita, T; Nakamura, M; Niinuma, H; Nishida, Y; Ochiai, M; Ohira, H; Okada, H; Omiya, K; Shinke, T; Takiuchi, S; Tanaka, H; Ueda, Y; Yasaka, Y; Yokoi, H; Zen, K1
Armengaud, J; Barragan, P; Ben Amer, H; Berlan, J; Blanchard, D; Bressolette, E; Carrie, D; Cassat, C; Castellant, P; Cazaux, P; Champagnac, D; Darremont, O; Dauphin, R; Delarche, N; Didier, R; Druelles, P; Dupouy, P; Furber, A; Gilard, M; Gommeaux, A; Hovasse, T; Jouve, B; Kermarrec, A; Kiss, RG; Le Breton, H; Levy, G; Lyuycx-Bore, A; Maillard, L; Majwal, T; Morice, MC; Noor, HA; Noryani, AAL; Ohlmann, P; Ormezzano, O; Paganelli, F; Sainsous, J; Schneeberger, M; Ungi, I; Wojcik, J1
Chow, B; Erthal, F; Farkouh, M; Fortier, J; Glineur, D; Hage, A; Ko, G; Kulik, A; Larose, É; LeMay, M; Mesana, TG; Ruel, M; Tremblay, H; Une, D; Voisine, P1
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Aburadani, I; Inomata, J; Kinoshita, M; Kurokawa, K; Maruyama, M; Nagata, Y; Usuda, K1
Huber, K1
El Mallah, W; Moliterno, DJ1
Brilakis, ES; Klein, AJ1
Chen, X; Han, Y; Jiang, T; Jing, Q; Li, Y; Liu, H; Ma, Y; Wang, G; Wang, S; Wang, X; Yan, G; Yang, L; Zhang, L; Zhu, G1
Ji, H; Li, L; Lv, H; Shi, J; Wang, G; Wang, Y; Yuan, S1
Gerdts, E; Lønnebakken, MT; Pedersen, OM1
Witzenbichler, B1
Alfonso, F; Batalla, N; Carrillo, X; Cascant, P; Cequier, A; de la Torre, JM; Ferreira-González, I; García-Del Blanco, B; García-Dorado, D; Gómez-Hospital, JA; Larrousse, E; Marsal, JR; Martí, G; Martín, E; Martín-Yuste, V; Masotti-Centol, M; Mauri, J; Permanyer-Miralda, G; Ribera, A; Ruiz-Salmerón, R; Rumoroso, JR; Sabatè, M; Serra, A1
Benedetti, G; Biondi-Zoccai, G; Calcagno, S; Canali, E; Di Roma, A; Fedele, F; Guadagni, F; Lucisano, L; Mancone, M; Palmirotta, R; Pennacchi, M; Sardella, G; Stio, RE1
Bednar, F; Benesova, L; Kocka, V; Minarik, M; Motovska, Z; Osmancik, P; Paulu, P; Tousek, P; Widimsky, P1
Chen, X; Fang, R; Hu, J; Li, X; Su, J; Xu, J; Zhang, H1
Bal dit Sollier, C; Dillinger, JG; Drissa, A; Drouet, L; Henry, P; Logeart, D; Manzo Silberman, S; Sideris, G; Voicu, S1
Alexander, JH; Alexander, KP; Broderick, S; Granger, CB; Hess, CN; Lopes, RD; Mahaffey, KW; Newby, LK; Peterson, ED; Piccini, JP; Shaw, LK1
Darwish, OS; Iqbal, E1
Angiolillo, DJ; Bergmeijer, T; Brown, PB; Erlinge, D; Foley, D; Jakubowski, JA; James, S; Luo, J; Moser, B; Small, DS; Ten Berg, J; Wagner, H; Winters, KJ; Zhou, C1
Anstrom, KJ; Brennan, JM; Califf, RM; Douglas, PS; Eisenstein, EL; Peterson, ED; Wojdyla, D1
Bliden, KP; Chai, S; Figg, WD; Gibson, Q; Gurbel, PA; Horenstein, RB; Lewis, JP; Mitchell, BD; O'Connell, JR; Pacanowski, MA; Peer, CJ; Ryan, K; Shuldiner, AR; Spencer, SD; Tanner, K; Tantry, US1
Angiolillo, DJ; Bass, TA; Capodanno, D; Darlington, A; Desai, B; Ferreiro, JL; Guzman, LA; Kodali, MK; Patel, R; Rollini, F; Tello-Montoliu, A; Tomasello, SD; Ueno, M1
Kozan, Ö1
Bennett, MR1
Gao, RL; Han, YL; Jiang, TM; Jing, QM; Li, SM; Li, WM; Li, Y; Liu, HL; Qu, P; Xu, B; Yang, LX; Zhang, L; Zhang, QY1
Lee, HL; Lee, KN; Lee, SP1
Abizaid, A; Bhatt, DL; Botelho, RV; Castello, H; Costa, RA; de Paula, JE; Devito, FS; Feres, F; Gusmão, MO; King, SB; Leon, MB; Mangione, JA; Marin-Neto, JA; Nicolela, E; Perin, MA; Salvadori, D1
Abbott, JD; Faxon, D; Holper, E; Kelsey, S; Khandhar, S; Kip, KE; Kutcher, M; Lee, JS; Marroquin, OC; Mulukutla, SR; Selzer, F; Smith, C; Toma, C; Vlachos, HA; Williams, DO1
Ahn, JM; Kang, SJ; Kim, WJ; Kim, YH; Lee, CW; Lee, JY; Lee, SW; Park, DW; Park, SJ; Park, SW; Song, HG; Yun, SC1
Fujimoto, Y; Iwata, Y; Kadohira, T; Kitahara, H; Kobayashi, Y; Morino, T; Ohkubo, K; Sugimoto, K1
Albertal, M; Belardi, JA1
Cao, Y; Huang, Y; Ji, Q; Lin, Y; Liu, L; Lu, Z; Luo, C; shi, Y; Wang, X; Zeng, Q1
Ang, L; Ilapakurti, M; Lee, MS; Mahmud, E; Palakodeti, V; Thani, KB1
Barthélémy, O; Bellemain-Appaix, A; Bernasconi, F; Beygui, F; Collet, JP; Cucherat, M; Jacq, L; Montalescot, G; O'Connor, SA; Silvain, J1
Badr Eslam, R; Kaider, A; Lang, IM; Panzer, S1
Choi, WG; Kim, HS; Kim, SY; Koo, BK; Kwan, J; Park, CG; Park, J; Park, JB1
Chang, FY; Chen, TS; Hou, MC; Huang, CC; Huang, KW; Lee, FY; Leu, HB; Lin, HC; Lu, CL; Luo, JC1
Chai, H; Chen, M; Huang, DJ; Li, Q; Liu, W; Liu, XJ; Luo, XL; Peng, Y; Ren, X; Wang, XQ; Zhang, C; Zhao, ZG1
Cao, J; Cong, YL; Cui, H; Fan, L; Hu, GL; Hu, QQ; Leng, WX; Niu, H; Ren, JW1
Feng, CH; Stevenson, DD; White, AA1
Berg, R; Bolla, VH; Singh, M1
Beitelshees, AL; Bliden, KP; Damcott, CM; Faraday, N; Gibson, Q; Gong, Y; Gurbel, PA; Herzog, W; Horenstein, RB; Johnson, JA; Lewis, JP; Mitchell, BD; O'Connell, JR; Pakzy, R; Parsa, A; Pepine, CJ; Pollin, TI; Post, WS; Ryan, K; Shuldiner, AR; Tanner, K; Tantry, US1
Kübler, W1
Jagroop, IA; Malley, M; Mikhailidis, DP1
Bahrmann, P; Figulla, HR; Sigusch, HH; Surber, R1
Adams, J; Bauersachs, R; Graff, J; Harder, S; Klinkhardt, U; Lindhoff-Last, E1
Buettner, HJ; Hunziker, P; Marsch, S; Mueller, C; Neumann, FJ; Perruchoud, A; Roskamm, H1
Hildebrandt, PR; Husted, SE; Kristensen, SD; Nielsen, HK; Rasmussen, LH; Ziegler, BK1
Bliden, KP; Gurbel, PA; Hiatt, BL; O'Connor, CM1
Rebrov, AP; Voskoboĭ, VI1
Berger, PB; Brennan, D; Kereiakes, DJ; Saw, J; Serebruany, VL; Steinhubl, SR; Topol, EJ1
Averkov, OV1
Shalaev, SV1
Helenius, I; Remes, V1
Tendera, M; Wojakowski, W1
Roffi, M; Topol, EJ1
Chen, WH; Lau, CP; Lee, PY; Ng, W; Tse, HF1
Cavuşoğlu, E1
Santa-Cruz, RA; Steinhubl, SR1
Beinart, R; Bienart, R; Goldenberg, I; Guetta, V; Hod, H; Matetzky, S; Novikov, I; Pres, H; Savion, N; Shechter, M; Shenkman, B; Varon, D1
Ergun, MA; Erkan, A; Yalcin, R; Yurtcu, E1
Gandhi, PJ; Kiyanista, VA; Vishnevetsky, D1
Becker, RC; Ezekowitz, M; Guyatt, GH; Harrington, RA; Meade, TW; O'Connor, CM; Vorchheimer, DA1
De Jonghe, B; Fangio, P; Lachérade, JC; Outin, H; Terville, JP1
Diehm, C; Huber, R; Lawall, H1
André-Fouët, X; Boschat, J; Finet, G; Gilard, M; Ginon, I; Rioufol, G1
Füessl, HS1
Anand, SS; Tran, H1
Schulman, SP1
Gawaz, M; Gorchakova, O; Joost, A; Kastrati, A; Mocz, A; Schömig, A; von Beckerath, N1
Alfonso, F; Angiolillo, DJ; Bañuelos, C; Bernardo, E; Escaned, J; Fernández-Ortiz, A; Hernández-Antolín, R; Macaya, C; Moreno, R; Ramírez, C; Sabaté, M1
Berger, PP; Bollwein, H; Dibra, A; Dirschinger, J; Dotzer, F; Kastrati, A; Mehilli, J; Pache, J; Schömig, A; Schühlen, H; von Beckerath, N1
Frogley, M; Kubler, PA; Marrinan, MC; Pillans, PI1
Goldberg, SL1
Cheneau, E; Corso, P; Haile, E; Kapetanakis, EI; Kent, KM; Kuchulakanti, P; Lew, R; Pakala, R; Pichard, AD; Rha, SW; Satler, LF; Suddath, WO; Waksman, R1
Raja, SG1
Neukirch-Stoop, C; Silberman, S; Steg, PG1
Borja, J1
Albers, GW; Bernstein, RA1
Horváth, IG; Komócsi, A; Pintér, T1
Judge, HM; Peters, G; Smith, SM; Storey, RF1
Bavry, AA; Bhatt, DL; Helton, TJ; Kumbhani, DJ1
Dubiel, JS; Dudek, D; Dziewierz, A; Heba, G; Mielecki, W; Rakowski, T1
Ambrosini, V; Bolognese, L; Bongo, AS; Gaglione, A; Galassi, AR; Marzocchi, A; Petronio, AS; Savonitto, S; Tolaro, S1
Salam, AM1
Baumann, PQ; Schneider, DJ; Sobel, BE; Whitaker, DA1
Alfonso, F; Angiolillo, DJ; Bañuelos, C; Bass, TA; Bernardo, E; Cavallari, U; Costa, MA; Escaned, J; Fernandez-Ortiz, A; Hernández, R; Jimenez-Quevedo, P; Macaya, C; Moreno, R; Pignatti, PF; Ramírez, C; Sabaté, M; Trabetti, E1
Blann, A1
Aleil, B; Cazenave, JP; Gachet, C; Meyer, N; Mossard, JM1
Almsherqi, ZA; Deng, Y; McLachan, C1
Baggish, AL; Sabatine, MS1
Dropinski, J; Jakiela, B; Musial, J; Sanak, M; Szczeklik, A; Wegrzyn, W1
Aboujaoudé, S; Azar, RR; El-Osta, H; Germanos, M; Ghorra, P; Kassab, R; Salamé, E; Zoghbi, A1
Ekman, M; James, S; Sjögren, I1
Binkley, PF; Bray, PF; Cooke, GE; Ferketich, AK; Frid, DJ; Goldschmidt-Clermont, PJ; Liu-Stratton, Y; Magorien, RD; Moeschberger, ML1
Alfonso, F; Angiolillo, DJ; Bañuelos, C; Bass, TA; Bernardo, E; Costa, MA; Escaned, J; Fernandez-Ortiz, A; Hernández, R; Jimenez-Quevedo, P; Macaya, C; Moreno, R; Ramírez, C; Sabaté, M1
Goldhaber, SZ; Vallurupalli, NG1
Hsu, A; Kelly, RV; Steinhubl, S; Topol, E1
Gulba, DC; Klutmann, M; Tillmanns, C1
Bauriedel, G; Lüderitz, B; Nickenig, G; Schneider-Schmitt, M; Skowasch, D; Viktor, A1
Frundi, D; Hochholzer, W; Neumann, FJ; Trenk, D1
Bliden, KP; Gurbel, PA; Lau, WC; Tantry, US1
Hoffmann, R; Kaiser, A; Radke, PW; Schunkert, H; Weber, C; Zernecke, A1
Brandt, JT; Darstein, C; Jakubowski, JA; Jernberg, T; Naganuma, H; Payne, CD; Siegbahn, A; Wallentin, L; Winters, KJ1
Alfonso, F; Angiolillo, DJ; Bañuelos, C; Bass, TA; Bernardo, E; Cavallari, U; Costa, MA; Escaned, J; Fernandez-Ortiz, A; Hernández, R; Macaya, C; Moreno, R; Pignatti, PF; Ramírez, C; Sabaté, M; Trabetti, E1
Baldus, S; Böger, R; Heitzer, T; Karstens, M; Meinertz, T; Ortak, M; Rudolph, V; Schwedhelm, E; Sydow, K; Tschentscher, P1
Gadhvi, D; Lee-Wong, M; Resnick, D1
Hollman, JL; Olivier, AC1
Barnard, MR; Fox, ML; Frelinger, AL; Furman, MI; Li, Y; Linden, MD; Michelson, AD1
Chen, WH1
Andreassen, AK; Aukrust, P; Brosstad, F; Damås, JK; Frøland, SS; Gjertsen, E; Gullestad, L; Hansteen, V; Pedersen, TM; Semb, AG; Solum, NO; Ueland, T; Waehre, T; Yndestad, A1
Granitskiĭ, NA1
Fehér, G; Horváth, B; Késmárky, G; Koltai, K; Tóth, K1
Kastrati, A; Schömig, A; Sibbing, D; von Beckerath, N; von Beckerath, O1
Barnard, MR; Fox, ML; Frelinger, AL; Furman, MI; Lau, WC; Li, Y; Linden, MD; McLaughlin, TJ; Michelson, AD1
Miao, F; Wang, XY1
Bigalke, B; Gawaz, M; Geisler, T; Göhring, K; Langer, H; May, AE; Stellos, K; Wydymus, M; Zürn, C1
Mercanoglu, F; Meric, M; Nisanci, Y; Oflaz, H; Oncul, A; Ozcan, M; Pamukcu, B; Umman, B1
Alessi, MC; Bonnet, JL; Carvajal, J; Cuisset, T; Frere, C; Lambert, M; Lehmann, A; Morange, PE; Nait-Saidi, L; Quilici, J1
Faxon, DP; Nesto, RW1
Goeser, T; Grimberg, G; Jung, N; Kastrati, A; Lazar, A; Schömig, A; Schömig, E; Taubert, D; von Beckerath, N1
Anstrom, KJ; Califf, RM; Eisenstein, EL; Harrington, RA; Kandzari, DE; Kong, DF; Kramer, JM; Mark, DB; Matchar, DB; Peterson, ED; Schulman, KA; Shaw, LK; Tuttle, RH1
Bhatt, DL; Cannon, CP1
Kereiakes, DJ1
Munzel, T; Ostad, MA; Schinzel, R; Trautmann, C; Velich, N; Walter, U; Warnholtz, A1
Lepor, NE1
Domanovits, H; Edes, I; Edes, IF; Facskó, A; Farhan, S; Glogar, D; Gyöngyösi, M; Homorodi, N; Huber, K; Király, C; Kristóf, E; Maurer, G; Pavo, N; Sodeck, G; Strehblow, C; Szük, T1
Angiolillo, DJ; Bass, TA; Bernardo, E; Charlton, RK; Costa, MA; Desai, B; Guzman, LA; Shoemaker, SB; Yuan, H; Zenni, MM1
Atar, D; Malinin, AI; Serebruany, VL1
Bauersachs, J; Eigenthaler, M; Schäfer, A1
Avila, A; Brosius, S; Byrd, J; Dippel, EJ; Farland, L; Gehbauer, L; Jerin, M; Majetic, L; Robken, J; Shammas, G; Shammas, NW; Sharis, P; Stoakes, P; Winter, M1
Mercanoglu, F; Meric, M; Nisanci, Y; Oflaz, H; Oncul, A; Onur, I; Ozcan, M; Pamukcu, B; Umman, B1
Ayral, Y; Boltzen, U; Piorkowski, M; Rauch, U; Schultheiss, HP; Stellbaum, C; Szotowski, B; Willich, T1
Giannitsis, E; Hohlfeld, T; Ivandic, BT; Katus, HA; Schlick, P; Staritz, P1
Amin, S; Diamond, GA; Eshaghian, S; Kaul, S; Shah, PK1
Abbate, A; Agostoni, P; Biondi-Zoccai, GG; Lotrionte, M; Moretti, C; Sangiorgi, G; Sheiban, I; Valgimigli, M1
Csejtei, A; Feher, G; Kiss, I; Tettinger, A; Tibold, A1
Breall, JA; Kalaria, V; Karlsson, G; Rehman, J1
Cheng, JW1
Falcone, EL; Tangri, N1
Cannon, CP; Gibler, WB; Milford-Beland, S; Ohman, EM; Peterson, ED; Pollack, CV; Roe, MT; Tickoo, S1
Buch, AN; George, CE; Javaid, A; Kent, KM; Pichard, AD; Roy, P; Satler, LF; Singh, S; Smith, KA; Suddath, WO; Waksman, R1
Bigalke, B; Daub, K; Dösch, C; Gawaz, M; Geisler, T; Göhring-Frischholz, K; Herdeg, C; Kapp, M; Langer, H1
Belli, G; Presbitero, P; Rossi, M; Zavalloni, D1
Aydinalp, A; Ertan, C; Gulmez, O; Kaynar, G; Konas, D; Muderrisoglu, H; Ozin, B; Yildirir, A1
Biernat, M; Dropinski, J; Dziedzina, S; Jakiela, B; Plutecka, H; Sanak, M; Szczeklik, A; Wegrzyn, W1
Beckman, JA; Parikh, SA1
Bocksch, W; Boxberger, M; Degenhardt, R; Gross, M; Horstkotte, D; Nienaber, C; Schneider, H; Unverdorben, M; Vallbracht, C; Wiemer, M1
Abbate, R; Antoniucci, D; Antonucci, E; Gensini, GF; Giglioli, C; Gori, AM; Marcucci, R; Paniccia, R; Prisco, D1
Joyal, D; Rudski, L1
Banares, M; Gollapudi, RR; Lee, SS; Price, MJ; Sawhney, N; Schatz, RA; Teirstein, PS; Valencia, R; Wong, GB1
Cho, YH; Choi, SW; Chun, KJ; Hong, MK; Kim, HS; Kim, JH; Kim, YH; Ko, JK; Lee, CW; Lee, JH; Lee, NH; Lee, SW; Park, DW; Park, JH; Park, SJ; Park, SW; Seong, IW; Yun, SC2
Alviar, CL; Arikan, ME; Builes, A; del Conde, I; Granada, JF; Kleiman, NS; Lev, EI; Mathuria, N; Tellez, A; Vaduganathan, M1
Alfonso, F; Angiolillo, DJ; Bañuelos, C; Bass, TA; Bernardo, E; Costa, MA; Escaned, J; Fernandez-Ortiz, A; Guzman, LA; Hernández-Antolin, R; Jimenez-Quevedo, P; Macaya, C; Moreno, R; Palazuelos, J; Sabaté, M1
Schmaier, AH; Simon, DI1
Banning, AP; Buellesfeld, L; Colombo, A; Dawkins, KD; Grube, E; Guagliumi, G; Hauptman, K; Koglin, J; Marco, J; Popma, JJ; Russell, ME; Thuesen, L; Wijns, W; Zmudka, K1
Bigalke, B; Dietz, K; Drosch, T; Gawaz, M; Geisler, T; Grass, D; Herdeg, C; Stellos, K1
Gebel, JM1
Christiaens, L; Macchi, L1
Becker, RC; Gurbel, PA; Mann, KG; Michelson, AD; Steinhubl, SR1
Bierend, A; Böger, RH; Maas, R; Rau, T; Schwedhelm, E1
Ludington, KJ; Price, MJ; Simon, RA; Teirstein, PS; Valencia, R; von Tiehl, KF1
Braun, OO; Erlinge, D; Jakubowski, JA; James, S; Siegbahn, A; Sugidachi, A; Varenhorst, C; Wallentin, L; Winters, KJ1
Hjemdahl, P; Hofman-Bang, C; Ivert, T; Li, N; Perneby, C; Tornvall, P; Wallén, NH1
Chen, YD; Lü, SZ; Lu, YL1
Dawley, CA; Fletcher, SF; Walker, CW1
Ahn, TH; Ahn, Y; Bae, JH; Chae, IH; Hur, SH; Jeong, JW; Jeong, MH; Kang, WC; Kim, JH; Kim, KH; Kim, KY; Nam, CW; Oh, SK; Park, CG1
Arora, R; Bahekar, A; Handa, K; Khosla, S; Khraisat, A; Singh, S; Trivedi, A1
Amit, G; Leibowitz, D; Rott, D; Weiss, AT; Zahger, D1
Delate, T; Johnson, SG; Rogers, K; Witt, DM1
Alfonso, F; Angiolillo, DJ; Bass, TA; Bernardo, E; Desai, B; Fernandez-Ortiz, A; Guzman, LA; Hernández-Antolin, R; Macaya, C; Palazuelos, J; Weisberg, I; Zenni, MZ1
Bates, V; Forrest, A; Gengo, FM; Gengo, MF; Hourihane, M; Rainka, M; Robson, M1
Garner, J; Hergott, L; Owen, P; Page, RL1
LeLorier, J; Rinfret, S; Sheehy, O1
Engelhardt, A; Lask, S; Mügge, A; Neubauer, H1
Hobbs, L; Lyle, B1
Bertrand, OF; Costerousse, O; De Larochellière, R; Déry, JP; Faurie, B; Gleeton, O; Larose, E; Nguyen, CM; Noël, B; Proulx, G; Rodés-Cabau, J; Roy, L1
Beyar, R; Nikolsky, E1
Hackeng, CM; Kelder, JC; Postma, S; ten Berg, JM; Topcu, Y; van Werkum, JW; Verheugt, FW1
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Jamieson, DG; Skliut, M1
Batchelor, WB; Buchbinder, M; Dubois, CL; Fitzgerald, PJ; Gammon, R; Garg, J; Hasselblad, V; Hermiller, JB; Kereiakes, DJ; Krucoff, MW; Lansky, AJ; Mehran, R; O'Shaughnessy, CD; Petersen, JL; Schofer, J; Simonton, CA; Turco, MA; Verheye, S; Wijns, W1
Kastrati, A; Mann, JF; Mehilli, J; Ndrepepa, G; Pinkau, T; Schömig, A; Schulz, S1
Cannon, CP; Fox, KA; Hamdalla, HN; Mehta, SR; Sabatine, MS; Steinhubl, SR; Topol, EJ1
Aberle, LG; Alexander, JH; Becker, RC; Chan, MY; Chronos, N; Cohen, MG; Dyke, CK; Gilchrist, IC; Harrington, RA; Kleiman, NS; Lin, M; Melloni, C; Myles, SK; Rusconi, CP; Steinhubl, SR; Tonkens, RM; Vorchheimer, DA; Walder, J1
Coukell, AJ; Markham, A1
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Marks, AR; Marx, SO1
Golledge, P; Robinson, N; Timmis, A1
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Gilchrist, IC; Momplaisir, T; Nickolaus, MJ1
Bertolet, BD; Gupta, A; Miller, L1
Gersh, BJ; Verheugt, FW1

Reviews

152 review(s) available for clopidogrel and Coronary Artery Disease

ArticleYear
Prevalence and clinical impact of high platelet reactivity in patients with chronic kidney disease treated with percutaneous coronary intervention: An updated systematic review and meta-analysis.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2022, Volume: 99, Issue:4

    Topics: Blood Platelets; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prevalence; Renal Insufficiency, Chronic; Risk Factors; Thrombosis; Treatment Outcome

2022
Extended, standard, or De-escalation antiplatelet therapy for patients with coronary artery disease undergoing percutaneous coronary intervention? A trial-sequential, bivariate, influential, and network meta-analysis.
    European heart journal. Cardiovascular pharmacotherapy, 2022, Sep-29, Volume: 8, Issue:7

    Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Hemorrhage; Humans; Network Meta-Analysis; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Ticagrelor

2022
Platelet Function and Genotype after DES Implantation in East Asian Patients: Rationale and Characteristics of the PTRG-DES Consortium.
    Yonsei medical journal, 2022, Volume: 63, Issue:5

    Topics: Clinical Studies as Topic; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Drug-Eluting Stents; Genotype; Humans; Platelet Function Tests

2022
Racial and ethnic differences in pharmacotherapy to prevent coronary artery disease and thrombotic events.
    European heart journal. Cardiovascular pharmacotherapy, 2022, Sep-29, Volume: 8, Issue:7

    Topics: Cardiovascular Agents; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Fibrinolytic Agents; Hemostatics; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imidazoles; Lipids; Organosilicon Compounds; Warfarin

2022
Efficacy of ticagrelor compared to clopidogrel in improving endothelial function in patients with coronary artery disease: a systematic review.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2022, 09-01, Volume: 23, Issue:9

    Topics: Acute Coronary Syndrome; Clopidogrel; Coronary Artery Disease; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Ticagrelor; Treatment Outcome

2022
De-escalation of antiplatelet therapy in patients with coronary artery disease: Time to change our strategy?
    European journal of internal medicine, 2023, Volume: 110

    Topics: Acute Coronary Syndrome; Clopidogrel; Coronary Artery Disease; Hemorrhage; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Treatment Outcome

2023
Immature platelet fraction in cardiovascular diagnostics and antiplatelet therapy monitoring.
    Cardiology journal, 2023, Volume: 30, Issue:5

    Topics: Acute Coronary Syndrome; Blood Platelets; Clopidogrel; Coronary Artery Disease; Humans; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride

2023
Comparison of Different Chronic Maintenance Antithrombotic Strategies in Patients with Coronary Artery Disease: A Systematic Review and Network Meta-Analysis.
    Cardiovascular therapeutics, 2023, Volume: 2023

    Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Fibrinolytic Agents; Humans; Ischemic Stroke; Network Meta-Analysis; Platelet Aggregation Inhibitors; Rivaroxaban; Ticagrelor

2023
Dual antiplatelet therapy in coronary artery disease: from the past to the future prospective.
    Cardiovascular intervention and therapeutics, 2020, Volume: 35, Issue:2

    Topics: Acute Coronary Syndrome; Anticoagulants; Clopidogrel; Coronary Artery Disease; Drug-Eluting Stents; Dual Anti-Platelet Therapy; Heart Diseases; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Risk Assessment; Ticagrelor

2020
Assessing platelet reactivity after drug eluting stent implantation: state of the art.
    Expert review of cardiovascular therapy, 2020, Volume: 18, Issue:1

    Topics: Acute Coronary Syndrome; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Drug-Eluting Stents; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Platelet Function Tests; Purinergic P2Y Receptor Antagonists

2020
Efficacy and safety of clopidogrel versus prasugrel and ticagrelor for coronary artery disease treatment in patients with CYP2C19 LoF alleles: a systemic review and meta-analysis.
    British journal of clinical pharmacology, 2020, Volume: 86, Issue:8

    Topics: Acute Coronary Syndrome; Alleles; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Humans; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Ticagrelor; Treatment Outcome

2020
Antithrombotic strategies for patients with coronary and lower extremity peripheral artery diseases: a narrative review.
    Expert review of cardiovascular therapy, 2020, Volume: 18, Issue:12

    Topics: Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Lower Extremity; Peripheral Arterial Disease; Platelet Aggregation Inhibitors; Treatment Outcome

2020
Antithrombotic Therapy in Patients with Atrial Fibrillation Undergoing Percutaneous Coronary Intervention.
    Cardiology clinics, 2020, Volume: 38, Issue:4

    Topics: Administration, Oral; Anticoagulants; Atrial Fibrillation; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Purinergic P2Y Receptor Antagonists

2020
Effects of the
    Expert opinion on drug safety, 2020, Volume: 19, Issue:12

    Topics: Acute Coronary Syndrome; ATP Binding Cassette Transporter, Subfamily B; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Genotype; Hemorrhage; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide

2020
Meta-Analysis Comparing Ticagrelor or Prasugrel Versus Clopidogrel in Patients Undergoing Elective Percutaneous Coronary Intervention.
    The American journal of cardiology, 2021, 03-15, Volume: 143

    Topics: Clopidogrel; Coronary Artery Disease; Elective Surgical Procedures; Humans; Myocardial Infarction; Percutaneous Coronary Intervention; Perioperative Care; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Ticagrelor

2021
Association of CYP2C19 Loss-of-Function Alleles with Major Adverse Cardiovascular Events of Clopidogrel in Stable Coronary Artery Disease Patients Undergoing Percutaneous Coronary Intervention: Meta-analysis.
    Cardiovascular drugs and therapy, 2021, Volume: 35, Issue:6

    Topics: Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors

2021
Risk of major adverse cardiovascular events for concomitant use of clopidogrel and proton pump inhibitors in patients inheriting CYP2C19 loss-of-function alleles: meta-analysis.
    International journal of clinical pharmacy, 2021, Volume: 43, Issue:5

    Topics: Alleles; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Drug Interactions; Humans; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Risk Factors; Ticlopidine

2021
Risk of stroke in CYP2C19 LoF polymorphism carrier coronary artery disease patients undergoing clopidogrel therapy: An ethnicity-based updated meta-analysis.
    European journal of internal medicine, 2021, Volume: 90

    Topics: Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Ethnicity; Genotype; Humans; Platelet Aggregation Inhibitors; Stroke; Treatment Outcome

2021
Meta-analysis of effects of ABCB1 polymorphisms on clopidogrel response among patients with coronary artery disease.
    European journal of clinical pharmacology, 2017, Volume: 73, Issue:7

    Topics: Asian People; ATP Binding Cassette Transporter, Subfamily B; Clopidogrel; Coronary Artery Disease; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Risk Factors; Ticlopidine

2017
Antithrombotic strategies for preventing long-term major adverse cardiovascular events in patients with non-valvular atrial fibrillation who undergo percutaneous coronary intervention.
    Expert opinion on pharmacotherapy, 2017, Volume: 18, Issue:9

    Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Hemorrhage; Humans; Myocardial Ischemia; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Recurrence; Ticlopidine

2017
Antithrombotic therapy: Dual therapy after PCI in AF.
    Nature reviews. Cardiology, 2017, Volume: 14, Issue:11

    Topics: Antithrombins; Atrial Fibrillation; Clopidogrel; Coronary Artery Disease; Dabigatran; Drug Therapy, Combination; Humans; Percutaneous Coronary Intervention; Purinergic P2Y Receptor Antagonists; Thromboembolism

2017
CYP2C19 genotype and adverse cardiovascular outcomes after stent implantation in clopidogrel-treated Asian populations: A systematic review and meta-analysis.
    Platelets, 2019, Volume: 30, Issue:2

    Topics: Aged; Asian People; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Female; Genotype; Humans; Male; Middle Aged; Percutaneous Coronary Intervention

2019
Association between P2RY12 gene polymorphisms and adverse clinical events in coronary artery disease patients treated with clopidogrel: A systematic review and meta-analysis.
    Gene, 2018, May-30, Volume: 657

    Topics: Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Mutation; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Receptors, Purinergic P2Y12; Research Design; Ticlopidine

2018
Role of CYP2C19 genotype testing in clinical use of clopidogrel: is it really useful?
    Expert review of cardiovascular therapy, 2018, Volume: 16, Issue:5

    Topics: Acute Coronary Syndrome; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Genotype; Humans; Percutaneous Coronary Intervention; Pharmacogenetics; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Stents; Ticlopidine

2018
Post percutaneous coronary interventional adverse cardiovascular outcomes and bleeding events observed with prasugrel versus clopidogrel: direct comparison through a meta-analysis.
    BMC cardiovascular disorders, 2018, 05-02, Volume: 18, Issue:1

    Topics: Administration, Oral; Aged; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Risk Factors; Stroke; Time Factors; Treatment Outcome

2018
Advances in the Treatment of Stable Coronary Artery Disease and Peripheral Artery Disease.
    Critical pathways in cardiology, 2018, Volume: 17, Issue:2

    Topics: Anticoagulants; Aspirin; Clopidogrel; Coronary Artery Disease; DNA; Drug Therapy, Combination; Factor Xa; Factor Xa Inhibitors; Fibrinolytic Agents; Hemorrhage; Histones; Humans; Peripheral Arterial Disease; Platelet Aggregation Inhibitors; Rivaroxaban; Thrombosis; Warfarin

2018
Adverse clinical outcomes associated with double dose clopidogrel compared to the other antiplatelet regimens in patients with coronary artery disease: a systematic review and meta-analysis.
    BMC pharmacology & toxicology, 2018, Sep-03, Volume: 19, Issue:1

    Topics: Aspirin; Cilostazol; Clopidogrel; Coronary Artery Disease; Humans; Observational Studies as Topic; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Randomized Controlled Trials as Topic; Ticagrelor; Treatment Outcome

2018
CYP2C19 pharmacogenetics versus standard of care dosing for selecting antiplatelet therapy in patients with coronary artery disease: A meta-analysis of randomized clinical trials.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2019, 06-01, Volume: 93, Issue:7

    Topics: Clinical Decision-Making; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Drug Dosage Calculations; Drug Resistance; Humans; Percutaneous Coronary Intervention; Pharmacogenetics; Pharmacogenomic Testing; Pharmacogenomic Variants; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk Assessment; Risk Factors; Stents; Treatment Outcome

2019
Combination Antiplatelet and Oral Anticoagulant Therapy in Patients With Coronary and Peripheral Artery Disease.
    Circulation, 2019, 04-30, Volume: 139, Issue:18

    Topics: Administration, Oral; Anticoagulants; Aspirin; Clopidogrel; Coronary Artery Disease; Humans; Percutaneous Coronary Intervention; Peripheral Arterial Disease; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Thrombosis

2019
Aspirin Versus Clopidogrel Monotherapy for the Treatment of Patients with Stable Coronary Artery Disease: A Systematic Review and Meta-Analysis.
    Advances in therapy, 2019, Volume: 36, Issue:8

    Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Stroke

2019
Monitoring aspirin and clopidogrel response: testing controversies and recommendations.
    Molecular diagnosis & therapy, 2013, Volume: 17, Issue:3

    Topics: Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Platelet Function Tests; Precision Medicine; Stents; Thrombosis; Ticlopidine

2013
Comparison of on-treatment platelet reactivity between triple antiplatelet therapy with cilostazol and standard dual antiplatelet therapy in patients undergoing coronary interventions: a meta-analysis.
    Journal of cardiovascular pharmacology and therapeutics, 2013, Volume: 18, Issue:6

    Topics: Aspirin; Blood Platelets; Cilostazol; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Humans; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Tetrazoles; Thromboembolism; Ticlopidine

2013
Perioperative management of antiplatelet therapy in patients with a coronary stent who need noncardiac surgery: a systematic review of clinical practice guidelines.
    Chest, 2013, Volume: 144, Issue:6

    Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Elective Surgical Procedures; Hemorrhage; Humans; Metals; Perioperative Care; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Stents; Thromboembolism; Ticlopidine; Time Factors; Withholding Treatment

2013
New antiplatelet agents for cardiovascular disease.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2013, Nov-05, Volume: 185, Issue:16

    Topics: Adenosine; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Pyridines; Thiophenes; Ticagrelor; Ticlopidine; Treatment Outcome

2013
Use of antiplatelet agents in patients with atherosclerotic disease.
    Postgraduate medicine, 2013, Volume: 125, Issue:5

    Topics: Acute Coronary Syndrome; Adenosine; Aged; Aspirin; Atherosclerosis; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Risk Factors; Thiophenes; Ticagrelor; Ticlopidine

2013
Impact of new oral or intravenous P2Y12 inhibitors and clopidogrel on major ischemic and bleeding events in patients with coronary artery disease: a meta-analysis of randomized trials.
    Atherosclerosis, 2014, Volume: 233, Issue:2

    Topics: Acute Coronary Syndrome; Adenosine; Adenosine Monophosphate; Administration, Oral; Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Fibrinolytic Agents; Hemorrhage; Humans; Injections, Intravenous; Multicenter Studies as Topic; Myocardial Infarction; Piperazines; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Quinazolinones; Randomized Controlled Trials as Topic; Stents; Stroke; Sulfonamides; Thiophenes; Thrombolytic Therapy; Ticagrelor; Ticlopidine

2014
Unravelling the smokers' paradox: cigarette smoking, high-risk coronary artery disease and enhanced clinical efficacy of oral P2Y₁₂ inhibitors.
    Thrombosis and haemostasis, 2014, Volume: 111, Issue:6

    Topics: Adenosine; Administration, Oral; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Risk Reduction Behavior; Smoking; Thiophenes; Ticagrelor; Ticlopidine; Treatment Outcome

2014
Combining antiplatelet and antithrombotic therapy (triple therapy): what are the risks and benefits?
    The American journal of medicine, 2014, Volume: 127, Issue:7

    Topics: Aspirin; Atrial Fibrillation; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Platelet Aggregation Inhibitors; Risk Assessment; Ticlopidine; Warfarin

2014
Platelet-reactivity tests identify patients at risk of secondary cardiovascular events: a systematic review and meta-analysis.
    Journal of thrombosis and haemostasis : JTH, 2014, Volume: 12, Issue:5

    Topics: Aspirin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Risk Factors; Ticlopidine

2014
Pharmacogenomics of oral antiplatelet drugs.
    Pharmacogenomics, 2014, Volume: 15, Issue:4

    Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Humans; Meta-Analysis as Topic; Pharmacogenetics; Platelet Aggregation Inhibitors; Ticlopidine

2014
Rationale and design of The Intracoronary Stenting and Antithrombotic Regimen-Testing of a six-week versus a six-month clopidogrel treatment Regimen In Patients with concomitant aspirin and oraL anticoagulant therapy following drug-Eluting stenting (ISAR-
    American heart journal, 2014, Volume: 167, Issue:4

    Topics: Administration, Oral; Aspirin; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drug-Eluting Stents; Follow-Up Studies; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Thrombolytic Therapy; Ticlopidine

2014
A systematic review and critical assessment of 11 discordant meta-analyses on reduced-function CYP2C19 genotype and risk of adverse clinical outcomes in clopidogrel users.
    Genetics in medicine : official journal of the American College of Medical Genetics, 2015, Volume: 17, Issue:1

    Topics: Alleles; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Genotype; Humans; Pharmacogenetics; Platelet Aggregation Inhibitors; Publication Bias; Ticlopidine; Treatment Outcome

2015
Gene polymorphism of cytochrome P450 2C19*2 and clopidogrel resistance reflected by platelet function assays: a meta-analysis.
    European journal of clinical pharmacology, 2014, Volume: 70, Issue:9

    Topics: Aged; China; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Drug Resistance; France; Humans; Middle Aged; Odds Ratio; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Polymorphism, Genetic; Republic of Korea; Ticlopidine

2014
Managing antithrombotic therapy in patients with both atrial fibrillation and coronary heart disease.
    Clinical therapeutics, 2014, Sep-01, Volume: 36, Issue:9

    Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Fibrinolytic Agents; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Stroke; Ticlopidine; Vitamin K; Warfarin

2014
Meta-analysis of direct and indirect comparison of ticagrelor and prasugrel effects on platelet reactivity.
    The American journal of cardiology, 2015, Mar-15, Volume: 115, Issue:6

    Topics: Adenosine; Blood Platelets; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Piperazines; Platelet Aggregation; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Research Design; Thiophenes; Ticagrelor; Ticlopidine; Treatment Outcome

2015
Dual antiplatelet therapy for coronary artery disease.
    Circulation journal : official journal of the Japanese Circulation Society, 2015, Volume: 79, Issue:2

    Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Stents; Ticlopidine

2015
Meta-Analysis of Randomized Controlled Trials Comparing Risk of Major Adverse Cardiac Events and Bleeding in Patients With Prasugrel Versus Clopidogrel.
    The American journal of cardiology, 2015, Aug-01, Volume: 116, Issue:3

    Topics: Clopidogrel; Coronary Artery Disease; Global Health; Hemorrhage; Humans; Incidence; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Randomized Controlled Trials as Topic; Risk Factors; Thiophenes; Ticlopidine

2015
Comparing the effectiveness and safety between triple antiplatelet therapy and dual antiplatelet therapy in type 2 diabetes mellitus patients after coronary stents implantation: a systematic review and meta-analysis of randomized controlled trials.
    BMC cardiovascular disorders, 2015, Oct-09, Volume: 15

    Topics: Acute Coronary Syndrome; Aspirin; Cilostazol; Clopidogrel; Coronary Artery Disease; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Stents; Tetrazoles; Thrombosis; Ticlopidine

2015
Individual Proton Pump Inhibitors and Outcomes in Patients With Coronary Artery Disease on Dual Antiplatelet Therapy: A Systematic Review.
    Journal of the American Heart Association, 2015, Oct-29, Volume: 4, Issue:11

    Topics: Clopidogrel; Coronary Artery Disease; Drug Interactions; Drug Therapy, Combination; Humans; Observational Studies as Topic; Odds Ratio; Patient Safety; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Risk Assessment; Risk Factors; Ticlopidine; Treatment Outcome

2015
Reviewing the controversy surrounding pre-treatment with P2Y12 inhibitors in acute coronary syndrome patients.
    Expert review of cardiovascular therapy, 2016, Volume: 14, Issue:7

    Topics: Acute Coronary Syndrome; Adenosine; Adenosine Monophosphate; Clopidogrel; Coronary Artery Disease; Humans; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Ticagrelor; Ticlopidine

2016
Adherence to antiplatelet treatment with P2Y12 receptor inhibitors. Is there anything we can do to improve it? A systematic review of randomized trials.
    Current medical research and opinion, 2016, Volume: 32, Issue:8

    Topics: Clopidogrel; Coronary Artery Disease; Humans; Medication Adherence; Platelet Aggregation Inhibitors; Prospective Studies; Purinergic P2Y Receptor Antagonists; Randomized Controlled Trials as Topic; Retrospective Studies; Ticlopidine

2016
[Cholestasic toxic hepatitis due to clopidogrel in a patient with multiple conditions].
    Anales del sistema sanitario de Navarra, 2016, 04-29, Volume: 39, Issue:1

    Topics: Chemical and Drug Induced Liver Injury; Clopidogrel; Coronary Artery Disease; Humans; Platelet Aggregation Inhibitors; Ticlopidine

2016
Antiplatelet Management for Coronary Heart Disease: Advances and Challenges.
    Current atherosclerosis reports, 2016, Volume: 18, Issue:6

    Topics: Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Artery Disease; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Stents; Ticlopidine; United States

2016
Use of prasugrel in the setting of clopidogrel hypersensitivity: Case report and systematic review of the literature.
    Platelets, 2016, Volume: 27, Issue:8

    Topics: Adult; Clopidogrel; Coronary Artery Disease; Drug Hypersensitivity; Drug Substitution; Drug-Eluting Stents; Humans; Male; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Ticlopidine

2016
Aspirin, Plavix, and Other Antiplatelet Medications: What the Oral and Maxillofacial Surgeon Needs to Know.
    Oral and maxillofacial surgery clinics of North America, 2016, Volume: 28, Issue:4

    Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Humans; Medication Therapy Management; Oral Surgical Procedures; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Ticlopidine

2016
Risk and Benefits of Triple Therapy in Patients Undergoing Coronary Stent Implantation Requiring Oral Anticoagulation: A Meta-Analysis of 16 Studies.
    Cardiovascular drugs and therapy, 2016, Volume: 30, Issue:6

    Topics: Anticoagulants; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy; Fibrinolytic Agents; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Risk; Stents; Ticlopidine; Warfarin

2016
Three, six, or twelve months of dual antiplatelet therapy after DES implantation in patients with or without acute coronary syndromes: an individual patient data pairwise and network meta-analysis of six randomized trials and 11 473 patients.
    European heart journal, 2017, 04-07, Volume: 38, Issue:14

    Topics: Acute Coronary Syndrome; Analysis of Variance; Aspirin; Blood Vessel Prosthesis Implantation; Clopidogrel; Coronary Artery Disease; Death, Sudden, Cardiac; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Female; Graft Occlusion, Vascular; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Myocardial Revascularization; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Randomized Controlled Trials as Topic; Risk Assessment; Stroke; Ticlopidine; Treatment Outcome

2017
Derivation and validation of the predicting bleeding complications in patients undergoing stent implantation and subsequent dual antiplatelet therapy (PRECISE-DAPT) score: a pooled analysis of individual-patient datasets from clinical trials.
    Lancet (London, England), 2017, 03-11, Volume: 389, Issue:10073

    Topics: Aged; Aged, 80 and over; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Hemorrhage; Humans; Kaplan-Meier Estimate; Middle Aged; Multicenter Studies as Topic; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Randomized Controlled Trials as Topic; Risk Assessment; Stents; Ticlopidine; Treatment Outcome

2017
Clinical implications of clopidogrel resistance.
    Thrombosis and haemostasis, 2008, Volume: 100, Issue:2

    Topics: Angioplasty, Balloon, Coronary; Clopidogrel; Combined Modality Therapy; Coronary Artery Disease; Drug Resistance; Drug-Eluting Stents; Humans; Platelet Aggregation Inhibitors; Ticlopidine

2008
Revascularization treatment recommendations based on atherosclerotic disease distribution: coronary artery bypass grafting versus stenting.
    Current atherosclerosis reports, 2008, Volume: 10, Issue:5

    Topics: Angina Pectoris; Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Coronary Stenosis; Coronary Vessels; Diabetic Angiopathies; Drug-Eluting Stents; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Reoperation; Stents; Ticlopidine; Treatment Outcome

2008
Clopidogrel and aspirin in cardiovascular medicine: responders or not--current best available evidence.
    Cardiovascular & hematological agents in medicinal chemistry, 2008, Volume: 6, Issue:4

    Topics: Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Ticlopidine

2008
Aspirin and clopidogrel response variability: review of the published literature.
    Texas Heart Institute journal, 2008, Volume: 35, Issue:3

    Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Drug Interactions; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Secondary Prevention; Ticlopidine

2008
Role of antiplatelet therapy across the spectrum of patients with coronary artery disease.
    The American journal of cardiology, 2009, Feb-02, Volume: 103, Issue:3 Suppl

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome

2009
Variability in platelet response to the antiplatelet agents aspirin and clopidogrel: mechanisms, measurement, and clinical relevance.
    Critical pathways in cardiology, 2009, Volume: 8, Issue:1

    Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Probability; Risk Assessment; Sensitivity and Specificity; Severity of Illness Index; Ticlopidine; Treatment Outcome

2009
Benefits and risks of clopidogrel use in patients with coronary artery disease: evidence from randomized studies and registries.
    Clinical therapeutics, 2008, Volume: 30 Pt 2

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Hemorrhage; Humans; Platelet Activation; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Registries; Risk Assessment; Ticlopidine

2008
Recent advances in the management of coronary artery disease: highlights from the literature.
    Journal of cardiothoracic and vascular anesthesia, 2009, Volume: 23, Issue:2

    Topics: Blood Vessels; Clopidogrel; Coronary Angiography; Coronary Artery Bypass, Off-Pump; Coronary Artery Disease; Exercise Test; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Myocardial Revascularization; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Tomography, Emission-Computed; Treatment Outcome

2009
Percutaneous coronary intervention: assessing coronary vascular risk associated with bare-metal and drug-eluting stents.
    The American journal of managed care, 2009, Volume: 15, Issue:2 Suppl

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Drug-Eluting Stents; Fibrinolytic Agents; Humans; Platelet Aggregation Inhibitors; Risk Factors; Stents; Ticlopidine

2009
Significant gastrointestinal bleeding in patients at risk of coronary stent thrombosis.
    Reviews in cardiovascular medicine, 2009,Winter, Volume: 10, Issue:1

    Topics: Aged, 80 and over; Angioplasty, Balloon, Coronary; Anti-Bacterial Agents; Aspirin; Clopidogrel; Coronary Artery Disease; Drug-Eluting Stents; Duodenal Ulcer; Endoscopy, Gastrointestinal; Female; Helicobacter Infections; Helicobacter pylori; Humans; Peptic Ulcer Hemorrhage; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Proton Pump Inhibitors; Risk Assessment; Risk Factors; Thrombosis; Ticlopidine; Treatment Outcome

2009
New antiplatelet drugs: beyond aspirin and clopidogrel.
    International journal of clinical practice, 2009, Volume: 63, Issue:5

    Topics: Adenosine; Adenosine Monophosphate; Aspirin; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Drug Design; Humans; Imines; Lactones; Naphthalenes; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Propionates; Purinergic P2 Receptor Antagonists; Pyridines; Thiophenes; Ticagrelor; Ticlopidine

2009
Possibility of a rebound phenomenon following antiplatelet therapy withdrawal: a look at the clinical and pharmacological evidence.
    Pharmacology & therapeutics, 2009, Volume: 123, Issue:2

    Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Risk Factors; Ticlopidine; Withholding Treatment

2009
Peri-procedural platelet function and platelet inhibition in percutaneous coronary intervention.
    JACC. Cardiovascular interventions, 2008, Volume: 1, Issue:2

    Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Resistance; Hemorrhage; Humans; Myocardial Infarction; Platelet Activation; Platelet Aggregation Inhibitors; Risk Assessment; Risk Factors; Thrombin; Ticlopidine; Treatment Outcome

2008
Platelet resistance to antiplatelet drugs.
    Recent patents on cardiovascular drug discovery, 2009, Volume: 4, Issue:2

    Topics: Angioplasty, Balloon, Coronary; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug Resistance, Multiple; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine

2009
Assessment, mechanisms, and clinical implication of variability in platelet response to aspirin and clopidogrel therapy.
    The American journal of cardiology, 2009, Jul-15, Volume: 104, Issue:2

    Topics: Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Prognosis; Ticlopidine

2009
Inhibition of platelet aggregation with prasugrel and clopidogrel: an integrated analysis in 846 subjects.
    Platelets, 2009, Volume: 20, Issue:5

    Topics: Adult; Clopidogrel; Coronary Artery Disease; Data Collection; Female; Humans; Kinetics; Male; Middle Aged; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Thiophenes; Ticlopidine; Young Adult

2009
Effect of pharmaceutical interventions targeting thromboxane receptors and thromboxane synthase in cardiovascular and renal diseases.
    Future cardiology, 2009, Volume: 5, Issue:5

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Humans; Kidney Diseases; Platelet Aggregation Inhibitors; Proteinuria; Receptors, Thrombin; Thrombosis; Thromboxane A2; Thromboxane-A Synthase; Ticlopidine

2009
Current controversies in the pharmacogenomics of clopidogrel.
    Progress in cardiovascular nursing, 2009, Volume: 24, Issue:3

    Topics: Clopidogrel; Confidence Intervals; Coronary Artery Disease; Genotype; Humans; Myocardial Infarction; Pharmacogenetics; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Ticlopidine

2009
Clopidogrel before elective percutaneous coronary intervention.
    Journal of clinical pharmacology, 2010, Volume: 50, Issue:4

    Topics: Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Artery Disease; Elective Surgical Procedures; Humans; Postoperative Complications; Preoperative Care; Randomized Controlled Trials as Topic; Ticlopidine

2010
Dual antiplatelet therapy in coronary artery disease: a case-based approach.
    Cleveland Clinic journal of medicine, 2009, Volume: 76, Issue:11

    Topics: Acute Coronary Syndrome; Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Myocardial Infarction; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Stents; Thiophenes; Ticlopidine

2009
Aspirin and clopidogrel hyporesponsiveness and nonresponsiveness in patients with coronary artery stenting.
    Vascular health and risk management, 2009, Volume: 5

    Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Platelet Function Tests; Recurrence; Risk Assessment; Risk Factors; Stents; Thrombosis; Ticlopidine; Treatment Outcome

2009
Clopidogrel non-responsiveness and risk of cardiovascular morbidity. An updated meta-analysis.
    Thrombosis and haemostasis, 2010, Volume: 103, Issue:4

    Topics: Aged; Angioplasty, Balloon, Coronary; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Drug Resistance; Evidence-Based Medicine; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Odds Ratio; Platelet Aggregation Inhibitors; Publication Bias; Recurrence; Risk Assessment; Risk Factors; Ticlopidine; Treatment Outcome

2010
Factors associated with clopidogrel nonresponsiveness.
    Future cardiology, 2010, Volume: 6, Issue:2

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Clopidogrel; Coronary Artery Disease; Coronary Disease; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Humans; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Proton Pump Inhibitors; Smoking; Ticlopidine; Treatment Failure

2010
Safety and efficacy of abciximab as an adjunct to percutaneous coronary intervention.
    Vascular health and risk management, 2010, Mar-03, Volume: 6

    Topics: Abciximab; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Clopidogrel; Coronary Artery Disease; Electrocardiography; Hirudins; Humans; Immunoglobulin Fab Fragments; Peptide Fragments; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Randomized Controlled Trials as Topic; Recombinant Proteins; Ticlopidine

2010
Cytochrome P450 2C19*2 polymorphism and cardiovascular recurrences in patients taking clopidogrel: a meta-analysis.
    The pharmacogenomics journal, 2011, Volume: 11, Issue:3

    Topics: Adolescent; Adult; Aged; Aryl Hydrocarbon Hydroxylases; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Genetic Association Studies; Genotype; Humans; Middle Aged; Polymorphism, Genetic; Recurrence; Risk Factors; Thrombosis; Ticlopidine; United States

2011
The role of antiplatelet therapy in the secondary prevention of coronary artery disease.
    Current opinion in cardiology, 2010, Volume: 25, Issue:4

    Topics: Adenosine; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Interactions; Drug Therapy, Combination; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Risk Factors; Secondary Prevention; Thiophenes; Thromboxane A2; Ticagrelor; Ticlopidine

2010
Antiplatelet therapy in percutaneous coronary intervention: recent advances in oral antiplatelet agents.
    Current opinion in cardiology, 2010, Volume: 25, Issue:4

    Topics: Adenosine; Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Aspirin; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Drug Therapy, Combination; Humans; Piperazines; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Prasugrel Hydrochloride; Pyridines; Risk Factors; Thiophenes; Ticagrelor; Ticlopidine

2010
Platelet P2Y₁₂ receptor inhibition: an update on clinical drug development.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2010, Volume: 10, Issue:4

    Topics: Adenosine Diphosphate; Angioplasty, Balloon, Coronary; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Drug Design; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Pyridines; Receptors, Purinergic P2Y12; Ticlopidine

2010
[Antiplatelet therapy in coronary heart disease. Some problems and achivements].
    Kardiologiia, 2010, Volume: 50, Issue:6

    Topics: Acute Coronary Syndrome; Adenosine; Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Aspirin; Blood Platelets; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Drug Interactions; Drug Resistance; Gastrointestinal Hemorrhage; Humans; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Polymorphism, Genetic; Prasugrel Hydrochloride; Proton Pump Inhibitors; Purinergic P2Y Receptor Antagonists; Receptor, PAR-1; Thiophenes; Ticagrelor; Ticlopidine; United States; United States Food and Drug Administration

2010
[Platelet inhibition with prasugrel].
    Deutsche medizinische Wochenschrift (1946), 2010, Volume: 135, Issue:31-32

    Topics: Acute Coronary Syndrome; Administration, Oral; Angina, Unstable; Biological Availability; Clopidogrel; Coronary Artery Disease; Humans; Metabolic Clearance Rate; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Randomized Controlled Trials as Topic; Secondary Prevention; Thiophenes; Ticlopidine

2010
Prognostic significance of high on-clopidogrel platelet reactivity after percutaneous coronary intervention: systematic review and meta-analysis.
    American heart journal, 2010, Volume: 160, Issue:3

    Topics: Angioplasty, Balloon, Coronary; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Humans; Intention to Treat Analysis; Myocardial Infarction; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Point-of-Care Systems; Predictive Value of Tests; Prognosis; Stents; Thrombosis; Ticlopidine

2010
Cytochrome P450 2C19 polymorphism is associated with poor clinical outcomes in coronary artery disease patients treated with clopidogrel.
    Molecular biology reports, 2011, Volume: 38, Issue:3

    Topics: Aryl Hydrocarbon Hydroxylases; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Humans; Myocardial Infarction; Myocardial Ischemia; Odds Ratio; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Stents; Stroke; Thrombosis; Ticlopidine; Treatment Outcome

2011
[Dilemma between gastroprotection and cardiovascular prevention].
    Deutsche medizinische Wochenschrift (1946), 2010, Volume: 135, Issue:44

    Topics: Alleles; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aryl Hydrocarbon Hydroxylases; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Cytochrome P-450 CYP2C19; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Drug-Eluting Stents; Humans; Long-Term Care; Mutation; Omeprazole; Peptic Ulcer Hemorrhage; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Proton Pump Inhibitors; Randomized Controlled Trials as Topic; Recurrence; Risk Factors; Survival Analysis; Ticlopidine; Treatment Outcome

2010
Ticagrelor: from discovery to Phase III clinical trial.
    Future cardiology, 2010, Volume: 6, Issue:6

    Topics: Acute Coronary Syndrome; Adenosine; Adenosine Diphosphate; Clinical Trials, Phase III as Topic; Clopidogrel; Coronary Artery Disease; Humans; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Ticagrelor; Ticlopidine

2010
The onset of inhibition of platelet aggregation with prasugrel compared with clopidogrel loading doses using gatekeeping analysis of integrated clinical pharmacology data.
    Journal of cardiovascular pharmacology, 2011, Volume: 57, Issue:3

    Topics: Clopidogrel; Coronary Artery Disease; Cross-Over Studies; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Female; Humans; Male; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Thiophenes; Ticlopidine; Time Factors

2011
Genetic variability in response to clopidogrel therapy and its clinical implications.
    Thrombosis and haemostasis, 2011, Volume: 105 Suppl 1

    Topics: Aryl Hydrocarbon Hydroxylases; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; DNA Mutational Analysis; Genetic Variation; Humans; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Precision Medicine; Predictive Value of Tests; Ticlopidine

2011
Platelet function variability and non-genetic causes.
    Thrombosis and haemostasis, 2011, Volume: 105 Suppl 1

    Topics: Blood Platelets; Clinical Trials as Topic; Clopidogrel; Comorbidity; Coronary Artery Disease; Diabetes Mellitus; Drug Interactions; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Ticlopidine

2011
Personalized antiplatelet therapy: review of the latest clinical evidence.
    Current cardiology reports, 2011, Volume: 13, Issue:4

    Topics: Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Cytochrome P-450 CYP2C19; Drug Resistance; Evidence-Based Medicine; Humans; Platelet Aggregation Inhibitors; Primary Prevention; Stents; Ticlopidine

2011
Antiplatelet drug therapy: role of pharmacodynamic and genetic testing.
    Future cardiology, 2011, Volume: 7, Issue:3

    Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Humans; Pharmacogenetics; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine

2011
Meta-analyses of the association between cytochrome CYP2C19 loss- and gain-of-function polymorphisms and cardiovascular outcomes in patients with coronary artery disease treated with clopidogrel.
    Heart (British Cardiac Society), 2012, Volume: 98, Issue:2

    Topics: Aryl Hydrocarbon Hydroxylases; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Genotype; Hemorrhage; Humans; Pharmacogenetics; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Risk Factors; Ticlopidine

2012
Benefits and risks of using clopidogrel before coronary artery bypass surgery: systematic review and meta-analysis of randomized trials and observational studies.
    The Journal of thoracic and cardiovascular surgery, 2012, Volume: 143, Issue:3

    Topics: Blood Transfusion; Clinical Trials as Topic; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Drug Administration Schedule; Evidence-Based Medicine; Hemorrhage; Humans; Myocardial Infarction; Patient Selection; Platelet Aggregation Inhibitors; Reoperation; Risk Assessment; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome

2012
Anticipating and managing bleeding complications in patients with coronary stents who are receiving dual antiplatelet treatment.
    BMJ (Clinical research ed.), 2011, Jul-21, Volume: 343

    Topics: Blood Component Transfusion; Catheters, Indwelling; Clopidogrel; Coagulants; Coronary Artery Disease; Coronary Restenosis; Drug Interactions; Drug Therapy, Combination; Drug-Eluting Stents; Endoscopy, Gastrointestinal; Fibrinolytic Agents; Forecasting; Gastrointestinal Hemorrhage; Hemorrhage; Humans; Intracranial Hemorrhages; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Proton Pump Inhibitors; Risk Factors; Stents; Ticlopidine; Treatment Outcome

2011
Genotypic and phenotypic assessment of platelet function and response to P2Y12 antagonists.
    Current cardiology reports, 2011, Volume: 13, Issue:5

    Topics: Adenosine; Clopidogrel; Coronary Artery Disease; Female; Genetic Association Studies; Humans; Male; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2Y12; Thiophenes; Ticagrelor; Ticlopidine; Treatment Outcome

2011
Antiplatelet function variability in clopidogrel-treated patients: need for new antiplatelet agents.
    Fundamental & clinical pharmacology, 2012, Volume: 26, Issue:1

    Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Design; Drug Interactions; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2; Ticlopidine

2012
Variability of clopidogrel response in patients with type 2 diabetes mellitus.
    Diabetes & vascular disease research, 2011, Volume: 8, Issue:4

    Topics: Clopidogrel; Coronary Artery Disease; Diabetes Complications; Diabetes Mellitus, Type 2; Drug Monitoring; Drug Resistance; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Purinergic P2Y Receptor Antagonists; Ticlopidine; Treatment Outcome

2011
Antiplatelet therapy in the era of percutaneous coronary intervention with drug-eluting balloons.
    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2011, Volume: 7 Suppl K

    Topics: Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Agents; Clopidogrel; Coated Materials, Biocompatible; Coronary Artery Disease; Coronary Restenosis; Drug Delivery Systems; Drug Therapy, Combination; Equipment Design; Evidence-Based Medicine; Humans; Patient Selection; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Risk Assessment; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome

2011
Adverse cardiovascular effects of concomitant use of proton pump inhibitors and clopidogrel in patients with coronary artery disease: a systematic review and meta-analysis.
    Archives of medical research, 2012, Volume: 43, Issue:3

    Topics: Clopidogrel; Coronary Artery Disease; Drug Interactions; Drug Therapy, Combination; Humans; Proton Pump Inhibitors; Ticlopidine; Treatment Outcome

2012
The effectiveness and safety of triple-antiplatelet treatment based on cilostazol for patients receiving percutaneous coronary intervention: a meta-analysis.
    Clinical cardiology, 2012, Volume: 35, Issue:10

    Topics: Angioplasty, Balloon, Coronary; Aspirin; Cilostazol; Clopidogrel; Confidence Intervals; Coronary Artery Disease; Coronary Restenosis; Drug Therapy, Combination; Humans; Odds Ratio; Platelet Aggregation Inhibitors; Tetrazoles; Ticlopidine

2012
Meta-analysis of cytochrome P450 2C19 polymorphism and risk of adverse clinical outcomes among coronary artery disease patients of different ethnic groups treated with clopidogrel.
    The American journal of cardiology, 2012, Aug-15, Volume: 110, Issue:4

    Topics: Aryl Hydrocarbon Hydroxylases; Clopidogrel; Cohort Studies; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Ethnicity; Humans; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Prospective Studies; Randomized Controlled Trials as Topic; Risk Assessment; Ticlopidine; Treatment Outcome

2012
Translational platelet research in patients with coronary artery disease: what are the major knowledge gaps?
    Thrombosis and haemostasis, 2012, Volume: 108, Issue:1

    Topics: Adenosine Diphosphate; Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Biomarkers, Pharmacological; Blood Platelets; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Humans; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Ticlopidine; Translational Research, Biomedical; Treatment Outcome

2012
Challenges and perspectives of antiplatelet therapy in patients with diabetes mellitus and coronary artery disease.
    Current pharmaceutical design, 2012, Volume: 18, Issue:33

    Topics: Aspirin; Blood Glucose; Blood Platelets; Clopidogrel; Coronary Artery Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Humans; Insulin; Insulin Resistance; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine; Treatment Outcome

2012
A brief review of the past and future of platelet P2Y12 antagonist.
    Coronary artery disease, 2012, Volume: 23, Issue:6

    Topics: Acute Coronary Syndrome; Adenosine; Adenosine Monophosphate; Clopidogrel; Coronary Artery Disease; Humans; Myocardial Infarction; Piperazines; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Quinazolinones; Stents; Sulfonamides; Thiophenes; Thrombosis; Ticagrelor; Ticlopidine

2012
Advances in platelet function testing assessing bleeding complications in patients with coronary artery disease.
    Platelets, 2012, Volume: 23, Issue:7

    Topics: Acute Coronary Syndrome; Aspirin; Blood Platelets; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Hemorrhage; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Platelet Function Tests; Precision Medicine; Risk; Thrombosis; Ticlopidine

2012
Clopidogrel in coronary artery disease: update 2012.
    Advances in cardiology, 2012, Volume: 47

    Topics: Adenosine; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Humans; Myocardial Infarction; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Thiophenes; Ticagrelor; Ticlopidine; Treatment Outcome

2012
ABCB1 C3435T polymorphism and response to clopidogrel treatment in coronary artery disease (CAD) patients: a meta-analysis.
    PloS one, 2012, Volume: 7, Issue:10

    Topics: ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Clopidogrel; Coronary Artery Disease; Humans; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Ticlopidine

2012
The discovery of a new class of synaptic transmitters in smooth muscle 50 years ago and amelioration of coronary artery thrombosis.
    Acta physiologica (Oxford, England), 2013, Volume: 207, Issue:2

    Topics: Adenosine; Animals; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; History, 20th Century; Humans; Muscle, Smooth; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y; Ticagrelor; Ticlopidine

2013
Antiplatelet drug resistance and variability in response: the role of antiplatelet therapy monitoring.
    Current pharmaceutical design, 2013, Volume: 19, Issue:21

    Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Cost Savings; Drug Monitoring; Drug Resistance; Drug Substitution; Drug Therapy, Combination; Humans; Ischemia; Platelet Aggregation Inhibitors; Secondary Prevention; Thrombosis; Ticlopidine

2013
Association of clopidogrel pretreatment with mortality, cardiovascular events, and major bleeding among patients undergoing percutaneous coronary intervention: a systematic review and meta-analysis.
    JAMA, 2012, Dec-19, Volume: 308, Issue:23

    Topics: Acute Coronary Syndrome; Clopidogrel; Coronary Artery Disease; Endpoint Determination; Hemorrhage; Humans; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Preoperative Care; Randomized Controlled Trials as Topic; Registries; Stroke; Ticlopidine; Treatment Outcome

2012
[Secondary and primary prevention of coronary heart disease: platelet aggregation inhibitors and anticoagulants].
    Zeitschrift fur Kardiologie, 2002, Volume: 91 Suppl 2

    Topics: Anticoagulants; Aspirin; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Drug Interactions; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Recurrence; Risk Factors; Ticlopidine

2002
[Clopidogrel: background information and use in clinical practice].
    Ugeskrift for laeger, 2003, Apr-28, Volume: 165, Issue:18

    Topics: Arteriosclerosis; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Stroke; Thrombosis; Ticlopidine

2003
[Antiplatelet drugs in prevention and treatment of coronary heart disease: aspirin is obligatory, quite sufficient, and safe].
    Kardiologiia, 2003, Volume: 43, Issue:6

    Topics: Angiotensin-Converting Enzyme Inhibitors; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Interactions; Drug Resistance; Drug Tolerance; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Ticlopidine

2003
[Antiplatelet drugs in prevention of complications of arteriosclerotic diseases: it is necessary to move beyond aspirin].
    Kardiologiia, 2003, Volume: 43, Issue:6

    Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Death, Sudden, Cardiac; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Stroke; Ticlopidine

2003
Role of antiplatelet drugs in the prevention of cardiovascular events.
    Thrombosis research, 2003, Jun-15, Volume: 110, Issue:5-6

    Topics: Aspirin; Benzamidines; Clopidogrel; Coronary Artery Disease; Humans; Myocardial Infarction; Oximes; Piperidines; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyridines; Stroke; Ticlopidine; Treatment Outcome

2003
Percutaneous coronary intervention in diabetic patients with non-ST-segment elevation acute coronary syndromes.
    European heart journal, 2004, Volume: 25, Issue:3

    Topics: Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Coronary Restenosis; Diabetic Angiopathies; Drug Implants; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Stents; Syndrome; Thiazolidinediones; Ticlopidine

2004
The use of clopidogrel in patients with coronary artery disease.
    Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, 2004, Volume: 4, Issue:1

    Topics: Clopidogrel; Coronary Artery Disease; Humans; Platelet Aggregation Inhibitors; Ticlopidine

2004
Clopidogrel: how good is it and how does it work?
    Current cardiology reports, 2004, Volume: 6, Issue:4

    Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Endothelium, Vascular; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Recurrence; Ticlopidine; Treatment Outcome

2004
CD40 ligand: a novel target in the fight against cardiovascular disease.
    The Annals of pharmacotherapy, 2004, Volume: 38, Issue:9

    Topics: Cardiovascular Agents; Cardiovascular Diseases; CD40 Ligand; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Thiazolidinediones; Ticlopidine

2004
Antithrombotic therapy for coronary artery disease: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy.
    Chest, 2004, Volume: 126, Issue:3 Suppl

    Topics: Antithrombins; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Bypass; Coronary Artery Disease; Coronary Thrombosis; Electrocardiography; Evidence-Based Medicine; Fibrinolytic Agents; Heparin; Heparin, Low-Molecular-Weight; Humans; Myocardial Infarction; Randomized Controlled Trials as Topic; Risk Assessment; Ticlopidine

2004
Oral antiplatelet therapy in cerebrovascular disease, coronary artery disease, and peripheral arterial disease.
    JAMA, 2004, Oct-20, Volume: 292, Issue:15

    Topics: Administration, Oral; Angina Pectoris; Arteriosclerosis; Aspirin; Cerebrovascular Disorders; Clopidogrel; Coronary Artery Disease; Dipyridamole; Drug Therapy, Combination; Humans; Ischemic Attack, Transient; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Stroke; Thrombosis; Ticlopidine

2004
What is the risk of stent thrombosis associated with the use of paclitaxel-eluting stents for percutaneous coronary intervention?: a meta-analysis.
    Journal of the American College of Cardiology, 2005, Mar-15, Volume: 45, Issue:6

    Topics: Aged; Angioplasty, Balloon, Coronary; Antineoplastic Agents, Phytogenic; Aspirin; Blood Vessel Prosthesis Implantation; Clopidogrel; Coated Materials, Biocompatible; Coronary Artery Disease; Coronary Thrombosis; Female; Humans; Male; Middle Aged; Paclitaxel; Platelet Aggregation Inhibitors; Postoperative Complications; Risk Factors; Stents; Ticlopidine; Treatment Outcome

2005
The benefits of abciximab questioned in percutaneous coronary interventions following pretreatment with high-dose clopidogrel.
    Expert opinion on investigational drugs, 2005, Volume: 14, Issue:3

    Topics: Abciximab; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Humans; Immunoglobulin Fab Fragments; Ticlopidine

2005
Clopidogrel use in coronary artery disease.
    Expert review of cardiovascular therapy, 2006, Volume: 4, Issue:1

    Topics: Clopidogrel; Coronary Artery Disease; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine

2006
Gastrointestinal complications of dual antiplatelet therapy.
    Circulation, 2006, Mar-28, Volume: 113, Issue:12

    Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Duodenal Ulcer; Endoscopy, Digestive System; Gastrointestinal Diseases; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine

2006
Clopidogrel resistance: implications for coronary stenting.
    Current pharmaceutical design, 2006, Volume: 12, Issue:10

    Topics: Animals; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Receptors, Purinergic P2; Stents; Ticlopidine

2006
Thienopyridines in percutaneous coronary interventions: standard procedures and high risk subsets.
    Current pharmaceutical design, 2006, Volume: 12, Issue:10

    Topics: Angioplasty, Balloon, Coronary; Biocompatible Materials; Brachytherapy; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Humans; Metals; Platelet Aggregation Inhibitors; Stents; Thrombosis; Ticlopidine

2006
Antiplatelet resistance with aspirin and clopidogrel: is it real and does it matter?
    Current cardiology reports, 2006, Volume: 8, Issue:4

    Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine

2006
Impact of chronic kidney disease and diabetes on percutaneous coronary intervention outcomes.
    Reviews in cardiovascular medicine, 2006, Volume: 7 Suppl 4

    Topics: Abciximab; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Cardiovascular Diseases; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Diabetes Complications; Drug-Eluting Stents; Glucose; Humans; Immunoglobulin Fab Fragments; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Renal Insufficiency, Chronic; Risk Assessment; Risk Factors; Ticlopidine; Treatment Outcome

2006
Variable response to clopidogrel in patients with coronary artery disease.
    Seminars in thrombosis and hemostasis, 2007, Volume: 33, Issue:2

    Topics: Clopidogrel; Coronary Artery Disease; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome

2007
Role of clopidogrel in managing atherothrombotic cardiovascular disease.
    Annals of internal medicine, 2007, Mar-20, Volume: 146, Issue:6

    Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug Administration Schedule; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Ticlopidine

2007
Benefits of clopidogrel in patients undergoing coronary stenting significantly depend on loading dose: evidence from a meta-regression.
    American heart journal, 2007, Volume: 153, Issue:4

    Topics: Clopidogrel; Combined Modality Therapy; Coronary Artery Disease; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Regression Analysis; Stents; Ticlopidine

2007
Pharmacoeconomic analysis of clopidogrel in secondary prevention of coronary artery disease.
    Journal of managed care pharmacy : JMCP, 2007, Volume: 13, Issue:4

    Topics: Clopidogrel; Coronary Artery Disease; Cost-Benefit Analysis; Economics, Pharmaceutical; Humans; Ticlopidine; United States

2007
Contemporary use of clopidogrel in patients with coronary artery disease.
    Current cardiology reports, 2007, Volume: 9, Issue:4

    Topics: Angioplasty, Balloon, Coronary; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug Resistance; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Treatment Outcome

2007
Monitoring of the antiplatelet drugs effect in patients with coronary artery disease: what is the real clinical impact?
    Current vascular pharmacology, 2007, Volume: 5, Issue:4

    Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Drug Monitoring; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine

2007
Platelet function monitoring in patients with coronary artery disease.
    Journal of the American College of Cardiology, 2007, Nov-06, Volume: 50, Issue:19

    Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Disease; Drug Resistance; Humans; Monitoring, Physiologic; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Risk Factors; Ticlopidine; Treatment Outcome

2007
Aspirin combined with clopidogrel (Plavix) decreases cardiovascular events in patients with acute coronary syndrome.
    American family physician, 2007, Dec-01, Volume: 76, Issue:11

    Topics: Acute Coronary Syndrome; Angina, Unstable; Aspirin; Clopidogrel; Coronary Artery Disease; Evidence-Based Medicine; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Thrombosis; Ticlopidine

2007
Increased incidence of in-stent thrombosis related to cocaine use: case series and review of literature.
    Journal of cardiovascular pharmacology and therapeutics, 2007, Volume: 12, Issue:4

    Topics: Adult; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Cocaine; Cocaine-Related Disorders; Coronary Artery Disease; Coronary Thrombosis; Female; Humans; Incidence; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Stents; Ticlopidine; Treatment Outcome

2007
Clopidogrel desensitization: case report and review of published protocols.
    Pharmacotherapy, 2008, Volume: 28, Issue:2

    Topics: Cardiac Catheterization; Clinical Protocols; Clopidogrel; Coronary Artery Disease; Desensitization, Immunologic; Drug Hypersensitivity; Drug-Eluting Stents; Exanthema; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine

2008
Update on antiplatelet agents, including MATCH, CHARISMA, and ESPRIT.
    Current cardiology reports, 2008, Volume: 10, Issue:1

    Topics: Aspirin; Brain Ischemia; Clopidogrel; Coronary Artery Disease; Dipyridamole; Female; Humans; Ischemic Attack, Transient; Male; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine

2008
Efficacy and safety of clopidogrel pretreatment before percutaneous coronary intervention with and without glycoprotein IIb/IIIa inhibitor use.
    American heart journal, 2008, Volume: 155, Issue:5

    Topics: Aged; Angioplasty, Balloon, Coronary; Clopidogrel; Combined Modality Therapy; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Randomized Controlled Trials as Topic; Ticlopidine; Treatment Outcome

2008
Clopidogrel.
    Drugs, 1997, Volume: 54, Issue:5

    Topics: Animals; Clopidogrel; Coronary Artery Disease; Humans; Platelet Aggregation Inhibitors; Ticlopidine

1997
Antiplatelet agents and the role of clopidogrel in the prevention of secondary atherosclerotic events.
    Medicine and health, Rhode Island, 1999, Volume: 82, Issue:8

    Topics: Clopidogrel; Coronary Artery Disease; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine

1999
Prevention of heart failure.
    Current cardiology reports, 2002, Volume: 4, Issue:3

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anticholesteremic Agents; Antihypertensive Agents; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Diabetes Complications; Disease Progression; Health Behavior; Heart Failure; Humans; Hyperlipidemias; Hypertension; Platelet Aggregation Inhibitors; Prevalence; Renal Insufficiency; Risk Factors; Smoking; Ticlopidine; Ventricular Dysfunction, Left

2002
[Modern therapy in acute coronary syndrome].
    Medizinische Klinik (Munich, Germany : 1983), 2002, Apr-15, Volume: 97, Issue:4

    Topics: Angina, Unstable; Anticoagulants; Aspirin; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Survival Rate; Ticlopidine

2002
Aspirin beyond platelet inhibition.
    The American journal of cardiology, 2002, Jul-01, Volume: 90, Issue:1

    Topics: Abciximab; Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Aspirin; Clopidogrel; Coronary Artery Disease; Humans; Immunoglobulin Fab Fragments; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine

2002

Trials

274 trial(s) available for clopidogrel and Coronary Artery Disease

ArticleYear
Efficacy and Safety of Ticagrelor Monotherapy by Clinical Presentation: Pre-Specified Analysis of the GLOBAL LEADERS Trial.
    Journal of the American Heart Association, 2021, 09-21, Volume: 10, Issue:18

    Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Coronary Artery Disease; Drug-Eluting Stents; Dual Anti-Platelet Therapy; Hemorrhage; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Ticagrelor

2021
Comparative evaluation of standard maintenance-dose clopidogrel versus low-dose prasugrel in patients with stable coronary artery disease after percutaneous coronary intervention.
    International journal of cardiology, 2022, 06-01, Volume: 356

    Topics: Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Treatment Outcome

2022
Antiplatelet effect, safety, and pharmacokinetics of vicagrel in patients with coronary artery disease undergoing percutaneous coronary intervention.
    European heart journal. Cardiovascular pharmacotherapy, 2022, 12-02, Volume: 8, Issue:8

    Topics: Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Hemorrhage; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors

2022
Impact of one-month DAPT followed by aspirin monotherapy in patients undergoing percutaneous coronary intervention according to clinical presentation: a post hoc analysis of the randomised One-Month DAPT trial.
    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2022, Aug-19, Volume: 18, Issue:6

    Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Drug-Eluting Stents; Hemorrhage; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome

2022
Impact of diabetes mellitus on the pharmacodynamic effects of prasugrel and ticagrelor after switching from clopidogrel in patients with coronary artery disease.
    Journal of thrombosis and thrombolysis, 2022, Volume: 54, Issue:3

    Topics: Adenosine; Adenosine Diphosphate; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Diabetes Mellitus; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Prospective Studies; Ticagrelor

2022
Effect of cocoa (
    Open heart, 2022, Volume: 9, Issue:2

    Topics: Aspirin; Cacao; Chocolate; Clopidogrel; Coronary Artery Disease; Humans; Pilot Projects; Platelet Aggregation Inhibitors; Prospective Studies; Ticlopidine

2022
Efficacy and safety of rivaroxaban plus clopidogrel versus aspirin plus clopidogrel in patients with coronary atherosclerotic heart disease and gastrointestinal disease undergoing percutaneous coronary intervention: study protocol for a non-inferiority ra
    Trials, 2023, Mar-21, Volume: 24, Issue:1

    Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Gastrointestinal Diseases; Hemorrhage; Humans; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prospective Studies; Randomized Controlled Trials as Topic; Rivaroxaban; Treatment Outcome

2023
Genetic-Guided Oral P2Y
    JACC. Cardiovascular interventions, 2023, 04-10, Volume: 16, Issue:7

    Topics: Acute Coronary Syndrome; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Female; Hemorrhage; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prospective Studies; Purinergic P2Y Receptor Antagonists; Treatment Outcome

2023
Sex Differences in Midterm Prognostic Implications of High Platelet Reactivity After Percutaneous Coronary Intervention With Drug-Eluting Stents in East Asian Patients: Results From the PTRG-DES (Platelet Function and Genotype-Related Long-Term Prognosis
    Journal of the American Heart Association, 2023, 05-02, Volume: 12, Issue:9

    Topics: Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug-Eluting Stents; East Asian People; Female; Humans; Male; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prognosis; Risk Factors; Sex Factors; Treatment Outcome

2023
Effects of Edoxaban on the Cellular and Protein Phase of Coagulation in Patients with Coronary Artery Disease on Dual Antiplatelet Therapy with Aspirin and Clopidogrel: Results of the EDOX-APT Study.
    Thrombosis and haemostasis, 2020, Volume: 120, Issue:1

    Topics: Aged; Anticoagulants; Aspirin; Blood Coagulation; Clopidogrel; Coronary Artery Disease; Cyclooxygenase 1; Drug Interactions; Drug Therapy, Combination; Dual Anti-Platelet Therapy; Female; Humans; Male; Middle Aged; Pyridines; Receptors, Purinergic P2Y12; Survival Analysis; Thiazoles

2020
Prasugrel effectively reduces the platelet reactivity units in patients with genetically metabolic dysfunction of cytochrome P450 2C19 who are treated with long-term dual antiplatelet therapy after undergoing drug-eluting stent implantation.
    Heart and vessels, 2020, Volume: 35, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Drug Resistance; Drug Substitution; Drug-Eluting Stents; Dual Anti-Platelet Therapy; Female; Humans; Japan; Male; Middle Aged; Percutaneous Coronary Intervention; Pharmacogenomic Variants; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Risk Factors; Time Factors; Treatment Outcome

2020
Optimal strategy of switching from clopidogrel to ticagrelor in Chinese acute coronary syndrome patients with complicated coronary artery disease: the switching from clopidogrel to ticagrelor (SHIFT-CACS) study.
    Chinese medical journal, 2019, Oct-05, Volume: 132, Issue:19

    Topics: Acute Coronary Syndrome; Adult; Aged; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Ticagrelor

2019
Switching of Oral Anticoagulation Therapy After PCI in Patients With Atrial Fibrillation: The RE-DUAL PCI Trial Subanalysis.
    JACC. Cardiovascular interventions, 2019, 12-09, Volume: 12, Issue:23

    Topics: Administration, Oral; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Coronary Artery Disease; Dabigatran; Drug Substitution; Drug Therapy, Combination; Female; Hemorrhage; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Risk Factors; Ticagrelor; Time Factors; Treatment Outcome; Warfarin

2019
Dabigatran Dual Therapy Versus Warfarin Triple Therapy Post-PCI in Patients With Atrial Fibrillation and Diabetes.
    JACC. Cardiovascular interventions, 2019, 12-09, Volume: 12, Issue:23

    Topics: Administration, Oral; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Coronary Artery Disease; Dabigatran; Diabetes Mellitus; Drug Substitution; Drug Therapy, Combination; Female; Hemorrhage; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Risk Factors; Ticagrelor; Time Factors; Treatment Outcome; Warfarin

2019
The impact of cytochrome 450 and Paraoxonase polymorphisms on clopidogrel resistance and major adverse cardiac events in coronary heart disease patients after percutaneous coronary intervention.
    BMC pharmacology & toxicology, 2020, 01-03, Volume: 21, Issue:1

    Topics: Aged; Aryldialkylphosphatase; Asian People; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Drug Resistance; Female; Genotype; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Polymorphism, Genetic

2020
β-Amyloid and mitochondrial-derived peptide-c are additive predictors of adverse outcome to high-on-treatment platelet reactivity in type 2 diabetics with revascularized coronary artery disease.
    Journal of thrombosis and thrombolysis, 2020, Volume: 49, Issue:3

    Topics: Aged; Amyloid beta-Peptides; Blood Platelets; Clopidogrel; Coronary Artery Disease; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Humans; Male; Malondialdehyde; Middle Aged; Mitochondrial Proteins; Myocardial Revascularization; Platelet Activation; Risk Factors

2020
Ticagrelor and preconditioning in patients with stable coronary artery disease (TAPER-S): a randomized pilot clinical trial.
    Trials, 2020, Feb-17, Volume: 21, Issue:1

    Topics: Adolescent; Adult; Aged; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Clopidogrel; Coronary Artery Disease; Coronary Vessels; Female; Fractional Flow Reserve, Myocardial; Humans; Ischemic Preconditioning, Myocardial; Male; Microvessels; Middle Aged; Myocardial Reperfusion Injury; Percutaneous Coronary Intervention; Pilot Projects; Preoperative Care; Purinergic P2Y Receptor Antagonists; Randomized Controlled Trials as Topic; Ticagrelor; Treatment Outcome; Vascular Resistance; Young Adult

2020
Effect of Lesion Complexity and Clinical Risk Factors on the Efficacy and Safety of Dabigatran Dual Therapy Versus Warfarin Triple Therapy in Atrial Fibrillation After Percutaneous Coronary Intervention: A Subgroup Analysis From the REDUAL PCI Trial.
    Circulation. Cardiovascular interventions, 2020, Volume: 13, Issue:4

    Topics: Aged; Aged, 80 and over; Anticoagulants; Antithrombins; Aspirin; Atrial Fibrillation; Clopidogrel; Coronary Artery Disease; Dabigatran; Dual Anti-Platelet Therapy; Female; Hemorrhage; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prospective Studies; Risk Assessment; Risk Factors; Stents; Thromboembolism; Ticagrelor; Time Factors; Treatment Outcome; Warfarin

2020
The effect of antiplatelet drug on coronary endothelial and microvascular function: comparison with ticagrelor and clopidogrel.
    The Korean journal of internal medicine, 2021, Volume: 36, Issue:2

    Topics: Blood Platelets; Clopidogrel; Coronary Artery Disease; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Ticagrelor

2021
Optimal antiplatelet therapy for prevention of gastrointestinal injury evaluated by ANKON magnetically controlled capsule endoscopy: Rationale and design of the OPT-PEACE trial.
    American heart journal, 2020, Volume: 228

    Topics: Adult; Aspirin; Capsule Endoscopy; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Double-Blind Method; Drug-Eluting Stents; Dual Anti-Platelet Therapy; Female; Gastrointestinal Hemorrhage; Humans; Male; Outcome and Process Assessment, Health Care; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk Adjustment

2020
Effect of Genotype-Guided Oral P2Y12 Inhibitor Selection vs Conventional Clopidogrel Therapy on Ischemic Outcomes After Percutaneous Coronary Intervention: The TAILOR-PCI Randomized Clinical Trial.
    JAMA, 2020, 08-25, Volume: 324, Issue:8

    Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C19 Inhibitors; Female; Genotype; Genotyping Techniques; Hemorrhage; Heterozygote; Humans; Loss of Function Mutation; Male; Middle Aged; Percutaneous Coronary Intervention; Point-of-Care Testing; Precision Medicine; Purinergic P2Y Receptor Antagonists; Ticagrelor

2020
Efficacy and safety of ticagrelor and clopidogrel in East Asian patients with coronary artery disease undergoing percutaneous coronary intervention.
    Current medical research and opinion, 2020, Volume: 36, Issue:11

    Topics: Aged; Asian People; Clopidogrel; Coronary Artery Disease; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Preoperative Care; Ticagrelor; Treatment Outcome

2020
Safety of 3-Month Dual Antiplatelet Therapy After Implantation of Ultrathin Sirolimus-Eluting Stents With Biodegradable Polymer (Orsiro): Results From the SMART-CHOICE Trial.
    Journal of the American Heart Association, 2021, 01-05, Volume: 10, Issue:1

    Topics: Aged; Aspirin; Biodegradable Plastics; Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Drug-Eluting Stents; Dual Anti-Platelet Therapy; Female; Humans; Immunosuppressive Agents; Male; Outcome and Process Assessment, Health Care; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Sirolimus

2021
Rivaroxaban monotherapy versus combination therapy according to patient risk of stroke and bleeding in atrial fibrillation and stable coronary disease: AFIRE trial subanalysis.
    American heart journal, 2021, Volume: 236

    Topics: Aged; Aspirin; Atrial Fibrillation; Clopidogrel; Coronary Artery Disease; Factor Xa Inhibitors; Female; Hemorrhage; Humans; Male; Outcome and Process Assessment, Health Care; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Risk Adjustment; Rivaroxaban; Stroke

2021
CD36+/CD61+ Microparticles Correlate with the Risk of Percutaneous Cardiac Interventions in Coronary Artery Disease Patients and the Effects of Ticagrelor.
    Cardiovascular drugs and therapy, 2022, Volume: 36, Issue:3

    Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Clopidogrel; Coronary Artery Disease; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Ticagrelor

2022
Aspirin versus clopidogrel for chronic maintenance monotherapy after percutaneous coronary intervention (HOST-EXAM): an investigator-initiated, prospective, randomised, open-label, multicentre trial.
    Lancet (London, England), 2021, 06-26, Volume: 397, Issue:10293

    Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prospective Studies; Republic of Korea

2021
Impact of chronic kidney disease on the pharmacodynamic and pharmacokinetic effects of ticagrelor in patients with diabetes mellitus and coronary artery disease.
    European heart journal. Cardiovascular pharmacotherapy, 2022, 08-11, Volume: 8, Issue:5

    Topics: Clopidogrel; Coronary Artery Disease; Cross-Over Studies; Diabetes Mellitus; Humans; Platelet Aggregation Inhibitors; Prospective Studies; Renal Insufficiency, Chronic; Ticagrelor

2022
Biological effects of ticagrelor over clopidogrel in patients with stable coronary artery disease and chronic obstructive pulmonary disease.
    Thrombosis and haemostasis, 2017, 03-23, Volume: 117, Issue:6

    Topics: Adenosine; Aged; Anticoagulants; Apoptosis; Blood Platelets; Clopidogrel; Coronary Artery Disease; Cytokines; Endothelium, Vascular; Female; Human Umbilical Vein Endothelial Cells; Humans; Leukocytes, Mononuclear; Male; Middle Aged; Nitric Oxide; Percutaneous Coronary Intervention; Prospective Studies; Pulmonary Disease, Chronic Obstructive; Reactive Oxygen Species; Ticagrelor; Ticlopidine

2017
Impact of dual antiplatelet therapy after coronary artery bypass surgery on 1-year outcomes in the Arterial Revascularization Trial.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2017, Sep-01, Volume: 52, Issue:3

    Topics: Aspirin; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination; Europe; Female; Follow-Up Studies; Humans; Incidence; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Complications; Propensity Score; Survival Rate; Ticlopidine; Time Factors; Treatment Outcome

2017
Extended Duration Dual Antiplatelet Therapy After Coronary Stenting Among Patients With Peripheral Arterial Disease: A Subanalysis of the Dual Antiplatelet Therapy Study.
    JACC. Cardiovascular interventions, 2017, 05-08, Volume: 10, Issue:9

    Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Hemorrhage; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Peripheral Arterial Disease; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Proportional Hazards Models; Risk Factors; Stents; Stroke; Ticlopidine; Time Factors; Treatment Outcome

2017
PRotective Effect on the coronary microcirculation of patients with DIabetes by Clopidogrel or Ticagrelor (PREDICT): study rationale and design. A randomized multicenter clinical trial using intracoronary multimodal physiology.
    Cardiovascular diabetology, 2017, 05-19, Volume: 16, Issue:1

    Topics: Adenosine; Blood Platelets; Clinical Protocols; Clopidogrel; Coronary Artery Disease; Coronary Circulation; Diabetes Mellitus, Type 2; Humans; Microcirculation; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prospective Studies; Purinergic P2Y Receptor Antagonists; Research Design; Risk Factors; Spain; Ticagrelor; Ticlopidine; Time Factors; Treatment Outcome; Vasodilation

2017
Cangrelor reduces the risk of ischemic complications in patients with single-vessel and multi-vessel disease undergoing percutaneous coronary intervention: Insights from the CHAMPION PHOENIX trial.
    American heart journal, 2017, Volume: 188

    Topics: Adenosine Monophosphate; Administration, Oral; Aged; Cause of Death; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Global Health; Humans; Incidence; Infusions, Intravenous; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Postoperative Complications; Purinergic P2Y Receptor Antagonists; Survival Rate; Ticlopidine; Time Factors

2017
Variability of platelet response to clopidogrel is not related to adverse cardiovascular events in patients with stable coronary artery disease undergoing percutaneous coronary intervention.
    European journal of clinical pharmacology, 2017, Volume: 73, Issue:9

    Topics: Aged; Blood Platelets; Clopidogrel; Coronary Artery Disease; Female; Genotype; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Platelet Function Tests; Polymorphism, Genetic; Stents; Ticlopidine

2017
Use of the Dual-Antiplatelet Therapy Score to Guide Treatment Duration After Percutaneous Coronary Intervention.
    Annals of internal medicine, 2017, Jul-04, Volume: 167, Issue:1

    Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Drug Administration Schedule; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Retrospective Studies; Stents; Ticlopidine; Treatment Outcome

2017
Dual Antiplatelet Therapy for 6 Versus 18 Months After Biodegradable Polymer Drug-Eluting Stent Implantation.
    JACC. Cardiovascular interventions, 2017, 06-26, Volume: 10, Issue:12

    Topics: Absorbable Implants; Acute Coronary Syndrome; Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Female; Hemorrhage; Humans; Intention to Treat Analysis; Japan; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Polymers; Proportional Hazards Models; Prospective Studies; Prosthesis Design; Risk Factors; Stroke; Ticlopidine; Time Factors; Treatment Outcome

2017
6- Versus 24-Month Dual Antiplatelet Therapy After Implantation of Drug-Eluting Stents in Patients Nonresistant to Aspirin: Final Results of the ITALIC Trial (Is There a Life for DES After Discontinuation of Clopidogrel).
    JACC. Cardiovascular interventions, 2017, 06-26, Volume: 10, Issue:12

    Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Female; France; Hemorrhage; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Proportional Hazards Models; Prospective Studies; Prosthesis Design; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome

2017
Eight-year follow-up of the Clopidogrel After Surgery for Coronary Artery Disease (CASCADE) trial.
    The Journal of thoracic and cardiovascular surgery, 2018, Volume: 155, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Computed Tomography Angiography; Coronary Angiography; Coronary Artery Bypass; Coronary Artery Disease; Coronary Restenosis; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Outcome and Process Assessment, Health Care; Platelet Aggregation Inhibitors; Survival Analysis; Vascular Patency

2018
Safety of six-month dual antiplatelet therapy after second-generation drug-eluting stent implantation: OPTIMA-C Randomised Clinical Trial and OCT Substudy.
    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2018, 03-20, Volume: 13, Issue:16

    Topics: Aged; Aspirin; Cardiovascular Agents; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Predictive Value of Tests; Prospective Studies; Prosthesis Design; Republic of Korea; Sirolimus; Time Factors; Tomography, Optical Coherence; Treatment Outcome

2018
Comparison of 1-Year Outcomes of Triple (Aspirin + Clopidogrel + Cilostazol) Versus Dual Antiplatelet Therapy (Aspirin + Clopidogrel + Placebo) After Implantation of Second-Generation Drug-Eluting Stents into One or More Coronary Arteries: from the DECREA
    The American journal of cardiology, 2018, 02-15, Volume: 121, Issue:4

    Topics: Aspirin; Cilostazol; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Double-Blind Method; Drug Therapy, Combination; Drug-Eluting Stents; Endpoint Determination; Female; Humans; Immunosuppressive Agents; Male; Middle Aged; Myocardial Infarction; Myocardial Revascularization; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prospective Studies; Republic of Korea; Stroke; Survival Rate; Treatment Outcome

2018
Impact of Reticulated Platelets on the Antiplatelet Effect of the Intravenous P2Y12-Receptor Inhibitor Cangrelor.
    Thrombosis and haemostasis, 2018, Volume: 118, Issue:2

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Administration, Oral; Aged; Blood Platelets; Clopidogrel; Coronary Artery Disease; Female; Flow Cytometry; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Count; Platelet Function Tests; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Thienopyridines; Ticagrelor

2018
Pharmacodynamic Effects of Switching From Ticagrelor to Clopidogrel in Patients With Coronary Artery Disease: Results of the SWAP-4 Study.
    Circulation, 2018, 06-05, Volume: 137, Issue:23

    Topics: Aged; Blood Platelets; Cell Adhesion Molecules; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Microfilament Proteins; Middle Aged; Phosphoproteins; Platelet Aggregation; Platelet Function Tests; Prospective Studies; Ticagrelor

2018
Vasodilator-stimulated phosphoprotein-guided Clopidogrel maintenance therapy reduces cardiovascular events in atrial fibrillation patients requiring anticoagulation therapy and scheduled for percutaneous coronary intervention: a prospective cohort study.
    BMC cardiovascular disorders, 2018, 06-18, Volume: 18, Issue:1

    Topics: Aged; Anticoagulants; Atrial Fibrillation; Biomarkers; Blood Coagulation; Blood Platelets; Cell Adhesion Molecules; Clopidogrel; Coronary Artery Disease; Drug Monitoring; Female; Hemorrhage; Humans; International Normalized Ratio; Male; Microfilament Proteins; Middle Aged; Percutaneous Coronary Intervention; Phosphoproteins; Platelet Aggregation; Platelet Aggregation Inhibitors; Predictive Value of Tests; Prospective Studies; Risk Factors; Time Factors; Treatment Outcome

2018
Lower on-treatment platelet reactivity during everolimus-eluting stent implantation contributes to the resolution of post-procedural intra-stent thrombus: serial OCT observation in the PRASFIT-Elective study.
    Heart and vessels, 2018, Volume: 33, Issue:12

    Topics: Aged; Blood Platelets; Clopidogrel; Coronary Artery Disease; Coronary Vessels; Dose-Response Relationship, Drug; Double-Blind Method; Drug-Eluting Stents; Everolimus; Female; Follow-Up Studies; Graft Occlusion, Vascular; Humans; Male; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Tomography, Optical Coherence; Treatment Outcome

2018
Ticagrelor versus clopidogrel in patients with symptomatic peripheral artery disease and prior coronary artery disease: Insights from the EUCLID trial.
    Vascular medicine (London, England), 2018, Volume: 23, Issue:6

    Topics: Aged; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Double-Blind Method; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Peripheral Arterial Disease; Platelet Aggregation Inhibitors; Prospective Studies; Risk Factors; Stents; Stroke; Ticagrelor; Time Factors; Treatment Outcome

2018
Ticagrelor plus aspirin for 1 month, followed by ticagrelor monotherapy for 23 months vs aspirin plus clopidogrel or ticagrelor for 12 months, followed by aspirin monotherapy for 12 months after implantation of a drug-eluting stent: a multicentre, open-la
    Lancet (London, England), 2018, 09-15, Volume: 392, Issue:10151

    Topics: Adenosine; Aged; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Intention to Treat Analysis; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Ticagrelor; Ticlopidine

2018
Rationale and design of the EVOLVE Short DAPT Study to assess 3-month dual antiplatelet therapy in subjects at high risk for bleeding undergoing percutaneous coronary intervention.
    American heart journal, 2018, Volume: 205

    Topics: Aged; Aspirin; Brazil; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drug-Eluting Stents; Europe; Female; Hemorrhage; Humans; Incidence; Japan; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prospective Studies; Risk Factors; Treatment Outcome; United States

2018
Predictors of strut coverage of drug eluting stent implantation in diabetic patients.
    International journal of cardiology, 2019, Feb-01, Volume: 276

    Topics: Aged; Clopidogrel; Coronary Artery Disease; Diabetes Mellitus; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Male; Middle Aged; Platelet Aggregation Inhibitors; Predictive Value of Tests; Prosthesis Design; Sirolimus; Tomography, Optical Coherence; Treatment Outcome

2019
Platelet MicroRNA 365-3p Expression Correlates with High On-treatment Platelet Reactivity in Coronary Artery Disease Patients.
    Cardiovascular drugs and therapy, 2019, Volume: 33, Issue:2

    Topics: Aged; Aspirin; Blood Platelets; Cilostazol; Clopidogrel; Coronary Artery Disease; Drug Resistance; Drug Therapy, Combination; Female; Humans; Male; MicroRNAs; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prospective Studies; Purinergic P2Y Receptor Antagonists; Single-Blind Method; Stents; Taiwan; Ticagrelor; Time Factors; Treatment Outcome

2019
Dabigatran dual therapy with ticagrelor or clopidogrel after percutaneous coronary intervention in atrial fibrillation patients with or without acute coronary syndrome: a subgroup analysis from the RE-DUAL PCI trial.
    European heart journal, 2019, 05-14, Volume: 40, Issue:19

    Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Anticoagulants; Antithrombins; Aspirin; Atrial Fibrillation; Case-Control Studies; Clopidogrel; Coronary Artery Disease; Dabigatran; Drug Therapy, Combination; Dual Anti-Platelet Therapy; Elective Surgical Procedures; Female; Hemorrhage; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Proportional Hazards Models; Stroke; Ticagrelor; Warfarin

2019
Relationship of stroke and bleeding risk profiles to efficacy and safety of dabigatran dual therapy versus warfarin triple therapy in atrial fibrillation after percutaneous coronary intervention: An ancillary analysis from the RE-DUAL PCI trial.
    American heart journal, 2019, Volume: 212

    Topics: Aged; Anticoagulants; Atrial Fibrillation; Clopidogrel; Coronary Artery Disease; Dabigatran; Drug Therapy, Combination; Equivalence Trials as Topic; Female; Hemorrhage; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Risk Assessment; Stroke; Thromboembolism; Ticagrelor; Warfarin

2019
Effect of Ticagrelor Versus Clopidogrel on Aortic Stiffness in Patients With Coronary Artery Disease.
    Journal of the American Heart Association, 2019, 06-18, Volume: 8, Issue:12

    Topics: Aged; Aorta; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Single-Blind Method; Ticagrelor; Time Factors; Vascular Stiffness

2019
High-dose atorvastatin on the pharmacodynamic effects of double-dose clopidogrel in patients undergoing percutaneous coronary interventions: The ACHIDO (Atorvastatin and Clopidogrel HIgh DOse in stable patients with residual high platelet activity) study.
    JACC. Cardiovascular interventions, 2013, Volume: 6, Issue:2

    Topics: Age Factors; Aged; Aged, 80 and over; Aryl Hydrocarbon Hydroxylases; Atorvastatin; Blood Platelets; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Drug Interactions; Drug Resistance; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Italy; Male; Middle Aged; Odds Ratio; Percutaneous Coronary Intervention; Pharmacogenetics; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Purinergic P2Y Receptor Antagonists; Pyrroles; Receptors, Purinergic P2Y12; Risk Assessment; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome

2013
The influence of smoking status on the pharmacokinetics and pharmacodynamics of clopidogrel and prasugrel: the PARADOX study.
    Journal of the American College of Cardiology, 2013, Aug-06, Volume: 62, Issue:6

    Topics: Aged; Aryl Hydrocarbon Hydroxylases; Aspirin; Clopidogrel; Coronary Artery Disease; Cross-Over Studies; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C19; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Piperazines; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Prospective Studies; Purinergic P2Y Receptor Antagonists; Smoking; Thiophenes; Ticlopidine

2013
Current medical management of stable coronary artery disease before and after elective percutaneous coronary intervention.
    American heart journal, 2013, Volume: 165, Issue:5

    Topics: Adrenergic beta-Antagonists; Aged; Aspirin; Clopidogrel; Coloring Agents; Coronary Angiography; Coronary Artery Disease; Drug Therapy, Combination; Electrocardiography; Female; Follow-Up Studies; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Postoperative Care; Preoperative Care; Retrospective Studies; Severity of Illness Index; Ticlopidine; Treatment Outcome

2013
Prasugrel 5 mg in the very elderly attenuates platelet inhibition but maintains noninferiority to prasugrel 10 mg in nonelderly patients: the GENERATIONS trial, a pharmacodynamic and pharmacokinetic study in stable coronary artery disease patients.
    Journal of the American College of Cardiology, 2013, Aug-13, Volume: 62, Issue:7

    Topics: Administration, Oral; Age Factors; Aged; Aged, 80 and over; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Male; Middle Aged; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Reference Values; Severity of Illness Index; Single-Blind Method; Survival Rate; Thiophenes; Ticlopidine; Treatment Outcome

2013
Personalized antiplatelet therapy according to CYP2C19 genotype after percutaneous coronary intervention: a randomized control trial.
    International journal of cardiology, 2013, Oct-09, Volume: 168, Issue:4

    Topics: Aged; Aryl Hydrocarbon Hydroxylases; Asian People; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Female; Follow-Up Studies; Genotype; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Precision Medicine; Ticlopidine

2013
Comparison of antiplatelet effect and safety of clopidogrel napadisilate with clopidogrel bisulfate in coronary artery disease patients: multi-center, randomized, double-blind, phase IV, non-inferiority clinical trial.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2013, Volume: 13, Issue:6

    Topics: Aged; Clopidogrel; Coronary Artery Disease; Double-Blind Method; Drug Therapy, Combination; Female; Hemorrhage; Humans; Male; Middle Aged; Nervous System Diseases; Platelet Aggregation Inhibitors; Prospective Studies; Ticlopidine

2013
Pharmacodynamic effects of EV-077 in patients with diabetes mellitus and coronary artery disease on aspirin or clopidogrel monotherapy: results of an in vitro pilot investigation.
    Journal of thrombosis and thrombolysis, 2014, Volume: 37, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Diabetes Mellitus; Female; Humans; Male; Middle Aged; Pilot Projects; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptors, Thromboxane; Ticlopidine

2014
Enhanced active metabolite generation and platelet inhibition with prasugrel compared to clopidogrel regardless of genotype in thienopyridine metabolic pathways.
    Thrombosis and haemostasis, 2013, Volume: 110, Issue:6

    Topics: Aged; Alleles; Aryl Hydrocarbon Hydroxylases; Aryldialkylphosphatase; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biotransformation; Blood Platelets; Cell Adhesion Molecules; Cells, Cultured; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Female; Humans; Male; Microfilament Proteins; Middle Aged; Phosphoproteins; Piperazines; Platelet Activation; Polymorphism, Genetic; Prasugrel Hydrochloride; Prospective Studies; Pyridines; Receptors, Purinergic P2Y12; Thiophenes; Ticlopidine

2013
Adjunctive cilostazol versus double-dose clopidogrel after drug-eluting stent implantation: the HOST-ASSURE randomized trial (Harmonizing Optimal Strategy for Treatment of Coronary Artery Stenosis-Safety & Effectiveness of Drug-Eluting Stents & Anti-plate
    JACC. Cardiovascular interventions, 2013, Volume: 6, Issue:9

    Topics: Aged; Aspirin; Cilostazol; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug Therapy, Combination; Drug-Eluting Stents; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prospective Studies; Prosthesis Design; Republic of Korea; Risk Factors; Stroke; Tetrazoles; Ticlopidine; Time Factors; Treatment Outcome

2013
Comparison of dual versus triple antiplatelet therapy after drug-eluting stent according to stent length (from the pooled analysis of DECLARE trials).
    The American journal of cardiology, 2013, Dec-01, Volume: 112, Issue:11

    Topics: Aged; Aspirin; Cilostazol; Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Diabetes Complications; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prosthesis Implantation; Tetrazoles; Ticlopidine; Treatment Outcome

2013
Optimal duration of dual antiplatelet therapy after drug-eluting stent implantation: a randomized, controlled trial.
    Circulation, 2014, Jan-21, Volume: 129, Issue:3

    Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Combined Modality Therapy; Coronary Artery Disease; Drug Therapy, Combination; Drug-Eluting Stents; Female; Follow-Up Studies; Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Risk Factors; Ticlopidine; Treatment Outcome

2014
Combination of high on-treatment platelet aggregation and low deaggregation better predicts long-term cardiovascular events in PCI patients under dual antiplatelet therapy.
    Platelets, 2014, Volume: 25, Issue:6

    Topics: Aged; Aged, 80 and over; Blood Platelets; Clopidogrel; Coronary Artery Disease; Disease-Free Survival; Follow-Up Studies; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Postoperative Complications; Predictive Value of Tests; Survival Rate; Ticlopidine

2014
Lower mortality following pulmonary adverse events and sepsis with ticagrelor compared to clopidogrel in the PLATO study.
    Platelets, 2014, Volume: 25, Issue:7

    Topics: Adenosine; Aged; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Pneumonia; Sepsis; Ticagrelor; Ticlopidine; Treatment Outcome

2014
Effect of cilostazol addition or clopidogrel doubling on platelet function profiles in diabetic patients undergoing a percutaneous coronary intervention.
    Coronary artery disease, 2013, Volume: 24, Issue:8

    Topics: Blood Platelets; Cilostazol; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Cross-Over Studies; Diabetes Mellitus, Type 2; Drug Resistance; Drug Therapy, Combination; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Republic of Korea; Tetrazoles; Ticlopidine; Time Factors; Treatment Outcome

2013
Pharmacodynamic effects of standard dose prasugrel versus high dose clopidogrel in non-diabetic obese patients with coronary artery disease.
    Thrombosis and haemostasis, 2014, Volume: 111, Issue:2

    Topics: Aspirin; Biomarkers; Blood Platelets; Body Mass Index; Cell Adhesion Molecules; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Female; Florida; Humans; Male; Microfilament Proteins; Middle Aged; Obesity; Phosphoproteins; Phosphorylation; Piperazines; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Prospective Studies; Receptors, Purinergic P2Y12; Thiophenes; Ticlopidine; Time Factors; Treatment Outcome

2014
Three vs twelve months of dual antiplatelet therapy after zotarolimus-eluting stents: the OPTIMIZE randomized trial.
    JAMA, 2013, Dec-18, Volume: 310, Issue:23

    Topics: Acute Coronary Syndrome; Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Risk; Sirolimus; Stroke; Thrombosis; Ticlopidine

2013
Prasugrel or double-dose clopidogrel to overcome clopidogrel low-response--the TAILOR (Thrombocytes And IndividuaLization of ORal antiplatelet therapy in percutaneous coronary intervention) randomized trial.
    Platelets, 2014, Volume: 25, Issue:7

    Topics: Aged; Blood Platelets; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Percutaneous Coronary Intervention; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Prognosis; Thiophenes; Ticlopidine; Treatment Outcome

2014
Effects of clopidogrel therapy on oxidative stress, inflammation, vascular function, and progenitor cells in stable coronary artery disease.
    Journal of cardiovascular pharmacology, 2014, Volume: 63, Issue:4

    Topics: Aged; Biomarkers; Blood Vessels; Capillaries; Clopidogrel; Coronary Artery Disease; Cross-Over Studies; Double-Blind Method; Elasticity; Endothelium, Vascular; Female; Humans; Inflammation; Male; Middle Aged; Oxidative Stress; Platelet Aggregation Inhibitors; Prospective Studies; Stem Cells; Ticlopidine; Vascular Stiffness

2014
Pharmacodynamic comparison of pitavastatin versus atorvastatin on platelet reactivity in patients with coronary artery disease treated with dual antiplatelet therapy.
    Circulation journal : official journal of the Japanese Circulation Society, 2014, Volume: 78, Issue:3

    Topics: Aged; Aged, 80 and over; Aspirin; Atorvastatin; Clopidogrel; Coronary Artery Disease; Cross-Sectional Studies; Cytochrome P-450 CYP3A; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Platelet Aggregation Inhibitors; Pyrroles; Quinolines; Ticlopidine

2014
Clopidogrel metaboliser status based on point-of-care CYP2C19 genetic testing in patients with coronary artery disease.
    Thrombosis and haemostasis, 2014, May-05, Volume: 111, Issue:5

    Topics: Adolescent; Aged; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Female; Genetic Testing; Genotype; High-Throughput Screening Assays; Humans; Inactivation, Metabolic; International Cooperation; Male; Middle Aged; Point-of-Care Systems; Polymorphism, Genetic; Ticlopidine; Treatment Outcome; Young Adult

2014
Detecting a thienopyridine effect by platelet reactivity assessment and its implications for risk stratification.
    Journal of thrombosis and haemostasis : JTH, 2014, Volume: 12, Issue:4

    Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Piperazines; Platelet Activation; Point-of-Care Systems; Prasugrel Hydrochloride; Pyridines; Receptors, Purinergic P2Y12; Reproducibility of Results; ROC Curve; Sensitivity and Specificity; Thiophenes; Ticlopidine; Time Factors; Treatment Outcome

2014
Multicenter randomized trial of 3-month cilostazol use in addition to dual antiplatelet therapy after biolimus-eluting stent implantation for long or multivessel coronary artery disease.
    American heart journal, 2014, Volume: 167, Issue:2

    Topics: Aged; Cilostazol; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Coronary Restenosis; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Sirolimus; Tetrazoles; Ticlopidine; Time Factors; Treatment Outcome

2014
Comparison of the antiplatelet effect of two clopidogrel bisulfate formulations: Plavix and generic-Egitromb.
    Platelets, 2015, Volume: 26, Issue:1

    Topics: Adult; Chemistry, Pharmaceutical; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine; Treatment Outcome

2015
Clopidogrel improves microvascular endothelial function in subjects with stable coronary artery disease.
    Heart, lung & circulation, 2014, Volume: 23, Issue:6

    Topics: Aged; Blood Coagulation; Clopidogrel; Coronary Artery Disease; Endothelium, Vascular; Female; Humans; Male; Microvessels; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine; Time Factors

2014
Switching from clopidogrel to prasugrel in patients having coronary stent implantation.
    Journal of thrombosis and thrombolysis, 2014, Volume: 38, Issue:3

    Topics: Aged; Aged, 80 and over; Clopidogrel; Coronary Artery Disease; Drug Substitution; Female; Hemorrhage; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Piperazines; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Renal Insufficiency, Chronic; Sex Factors; Stents; Thiophenes; Thrombosis; Ticlopidine

2014
Impact of dual antiplatelet therapy on outcomes among aspirin-resistant patients following coronary artery bypass grafting.
    The American journal of cardiology, 2014, May-15, Volume: 113, Issue:10

    Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Croatia; Dose-Response Relationship, Drug; Drug Resistance; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Incidence; Male; Platelet Aggregation Inhibitors; Postoperative Care; Postoperative Complications; Retrospective Studies; Survival Rate; Ticlopidine; Treatment Outcome

2014
Impact of CYP3A5 polymorphism on platelet reactivity at percutaneous coronary intervention and after 9 months of aspirin and clopidogrel therapy in Japanese patients with coronary artery disease.
    European journal of clinical pharmacology, 2014, Volume: 70, Issue:6

    Topics: Asian People; Aspirin; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Drug Therapy, Combination; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Activation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Ticlopidine; Time Factors

2014
High clopidogrel dose in patients with chronic kidney disease having clopidogrel resistance after percutaneous coronary intervention.
    Angiology, 2015, Volume: 66, Issue:4

    Topics: Aged; China; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug Administration Schedule; Drug Resistance; Drug-Eluting Stents; Female; Hemorrhage; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Renal Insufficiency, Chronic; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome

2015
Pharmacodynamics, pharmacokinetics and safety of ticagrelor in Asian patients with stable coronary artery disease.
    Cardiovascular intervention and therapeutics, 2014, Volume: 29, Issue:4

    Topics: Adenosine; Adult; Aged; Aged, 80 and over; Asian People; Aspirin; Clopidogrel; Coronary Artery Disease; Double-Blind Method; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Function Tests; Purinergic P2Y Receptor Antagonists; Ticagrelor; Ticlopidine; Young Adult

2014
Platelet reactivity and cardiovascular events after percutaneous coronary intervention in patients with stable coronary artery disease: the Stent Thrombosis In Belgium (STIB) trial.
    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2014, Volume: 10, Issue:2

    Topics: Aged; Angina, Stable; Aspirin; Belgium; Blood Platelets; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug Therapy, Combination; Female; Hemorrhage; Humans; Logistic Models; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Odds Ratio; Percutaneous Coronary Intervention; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Prospective Studies; Risk Factors; Stents; Stroke; Ticlopidine; Time Factors; Treatment Outcome

2014
The effect of CYP2C19 gene polymorphisms on the pharmacokinetics and pharmacodynamics of prasugrel 5-mg, prasugrel 10-mg and clopidogrel 75-mg in patients with coronary artery disease.
    Thrombosis and haemostasis, 2014, Sep-02, Volume: 112, Issue:3

    Topics: Aged; Clinical Protocols; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Female; Genotype; Humans; Male; Middle Aged; Phenotype; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Prasugrel Hydrochloride; Thiophenes; Ticlopidine; Treatment Outcome

2014
Prasugrel but not high dose clopidogrel overcomes the lansoprazole neutralizing effect of P2Y12 inhibition: Results of the randomized DOSAPI study.
    European journal of clinical pharmacology, 2014, Volume: 70, Issue:9

    Topics: Adult; Aged; Anti-Ulcer Agents; Aspirin; Clopidogrel; Coronary Artery Disease; Double-Blind Method; Drug Interactions; Female; Humans; Lansoprazole; Male; Middle Aged; Piperazines; Platelet Activation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Thiophenes; Ticlopidine

2014
Variability of individual platelet reactivity over time in patients treated with clopidogrel: insights from the ELEVATE-TIMI 56 trial.
    Journal of the American College of Cardiology, 2014, Jul-29, Volume: 64, Issue:4

    Topics: Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome

2014
The net clinical benefit of personalized antiplatelet therapy in patients undergoing percutaneous coronary intervention.
    Clinical science (London, England : 1979), 2015, Volume: 128, Issue:2

    Topics: Aged; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Multivariate Analysis; Percutaneous Coronary Intervention; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Precision Medicine; Prospective Studies; Purinergic P2Y Receptor Antagonists; Regression Analysis; Thiophenes; Ticlopidine

2015
Saphenous vein graft failure after coronary artery bypass surgery: insights from PREVENT IV.
    Circulation, 2014, Oct-21, Volume: 130, Issue:17

    Topics: Aged; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Double-Blind Method; Female; Graft Occlusion, Vascular; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Complications; Predictive Value of Tests; Risk Assessment; Saphenous Vein; Ticlopidine; Vascular Patency

2014
A randomised trial of the pharmacodynamic and pharmacokinetic effects of ticagrelor compared with clopidogrel in Hispanic patients with stable coronary artery disease.
    Journal of thrombosis and thrombolysis, 2015, Volume: 39, Issue:1

    Topics: Adenosine; Aged; Blood Platelets; Clopidogrel; Coronary Artery Disease; Hispanic or Latino; Humans; Middle Aged; Platelet Activation; Purinergic P2Y Receptor Antagonists; Ticagrelor; Ticlopidine

2015
6- versus 24-month dual antiplatelet therapy after implantation of drug-eluting stents in patients nonresistant to aspirin: the randomized, multicenter ITALIC trial.
    Journal of the American College of Cardiology, 2015, Mar-03, Volume: 65, Issue:8

    Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Coronary Vessels; Drug-Eluting Stents; Early Termination of Clinical Trials; Europe; Everolimus; Female; Hemorrhage; Humans; Immunosuppressive Agents; Male; Middle Aged; Middle East; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Postoperative Complications; Sirolimus; Ticlopidine; Time Factors; Treatment Outcome

2015
Assessment of the efficacy and tolerability of clopidogrel napadisilate in Korean patients with coronary stenting: a multicenter, prospective, open-label, randomized trial.
    Current medical research and opinion, 2015, Volume: 31, Issue:3

    Topics: Aged; Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Drug Monitoring; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Republic of Korea; Ticlopidine; Treatment Outcome

2015
ISAR-SAFE: a randomized, double-blind, placebo-controlled trial of 6 vs. 12 months of clopidogrel therapy after drug-eluting stenting.
    European heart journal, 2015, May-21, Volume: 36, Issue:20

    Topics: Aged; Clopidogrel; Coronary Artery Disease; Double-Blind Method; Drug Administration Schedule; Drug-Eluting Stents; Female; Graft Occlusion, Vascular; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prosthesis Failure; Stroke; Ticlopidine; Treatment Outcome

2015
Impact of impaired glucose tolerance on clopidogrel response in patients with coronary artery disease.
    Journal of thrombosis and thrombolysis, 2015, Volume: 40, Issue:2

    Topics: Aged; Clopidogrel; Coronary Artery Disease; Female; Glucose Tolerance Test; Humans; Insulin Resistance; Male; Middle Aged; Ticlopidine; Time Factors

2015
Comparison of the antiplatelet effect of clopidogrel hydrogenosulfate and clopidogrel besylate in patients with stable coronary artery disease.
    Journal of thrombosis and thrombolysis, 2015, Volume: 40, Issue:3

    Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Drug Therapy, Combination; Female; Heterozygote; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Prospective Studies; Ticlopidine

2015
Outcomes with cangrelor versus clopidogrel on a background of bivalirudin: insights from the CHAMPION PHOENIX (A Clinical Trial Comparing Cangrelor to Clopidogrel Standard Therapy in Subjects Who Require Percutaneous Coronary Intervention [PCI]).
    JACC. Cardiovascular interventions, 2015, Volume: 8, Issue:3

    Topics: Adenosine Monophosphate; Aged; Anticoagulants; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Double-Blind Method; Female; Hemorrhage; Hirudins; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Odds Ratio; Peptide Fragments; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Recombinant Proteins; Risk Factors; Stents; Ticlopidine; Time Factors; Treatment Outcome

2015
Impact of clinical presentation on ischaemic and bleeding outcomes in patients receiving 6- or 24-month duration of dual-antiplatelet therapy after stent implantation: a pre-specified analysis from the PRODIGY (Prolonging Dual-Antiplatelet Treatment After
    European heart journal, 2015, May-21, Volume: 36, Issue:20

    Topics: Acute Coronary Syndrome; Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Female; Hemorrhage; Humans; Hyperplasia; Male; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prognosis; Stents; Stroke; Ticlopidine; Tunica Intima

2015
Zotarolimus-eluting versus bare-metal stents in uncertain drug-eluting stent candidates.
    Journal of the American College of Cardiology, 2015, Mar-03, Volume: 65, Issue:8

    Topics: Aged; Aged, 80 and over; Aspirin; Biocompatible Materials; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Coronary Restenosis; Drug-Eluting Stents; Female; Hemorrhage; Humans; Immunosuppressive Agents; Male; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Postoperative Complications; Risk Assessment; Risk Factors; Sirolimus; Ticlopidine; Treatment Outcome

2015
Reduced Effect of Aspirin and Clopidogrel Following Hybrid Coronary Revascularization.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2015, Volume: 21, Issue:7

    Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Female; Follow-Up Studies; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Prospective Studies; Ticlopidine

2015
Intrinsic platelet reactivity before start with clopidogrel as predictor for on-clopidogrel platelet function and long-term clinical outcome.
    Thrombosis and haemostasis, 2015, Volume: 114, Issue:1

    Topics: Aged; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Drug Resistance; Female; Germany; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Pharmacogenetics; Phenotype; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Polymorphism, Genetic; Predictive Value of Tests; Risk Assessment; Risk Factors; Stents; Ticlopidine; Time Factors; Treatment Outcome

2015
Rationale and design of the RT-AF study: Combination of rivaroxaban and ticagrelor in patients with atrial fibrillation and coronary artery disease undergoing percutaneous coronary intervention.
    Contemporary clinical trials, 2015, Volume: 43

    Topics: Adenosine; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Hemorrhage; Humans; Percutaneous Coronary Intervention; Research Design; Rivaroxaban; Ticagrelor; Ticlopidine; Warfarin

2015
Comparison of therapy with Ticagrelor, Prasugrel or high Clopidogrel dose in PCI patients with high on treatment platelet reactivity and genotype variation. TRIPLETE RESET trial.
    International journal of cardiology, 2015, Sep-01, Volume: 194

    Topics: Adenosine; Blood Platelets; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Dose-Response Relationship, Drug; Genetic Variation; Genotype; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Ticagrelor; Ticlopidine

2015
Omeprazole, pantoprazole, and CYP2C19 effects on clopidogrel pharmacokinetic-pharmacodynamic relationships in stable coronary artery disease patients.
    European journal of clinical pharmacology, 2015, Volume: 71, Issue:9

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Alleles; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Drug Interactions; Female; Genotype; Humans; Male; Middle Aged; Models, Biological; Omeprazole; Pantoprazole; Platelet Aggregation; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Ticlopidine

2015
Ticagrelor Versus Clopidogrel in Black Patients With Stable Coronary Artery Disease: Prospective, Randomized, Open-Label, Multiple-Dose, Crossover Pilot Study.
    Circulation. Cardiovascular interventions, 2015, Volume: 8, Issue:7

    Topics: Adenosine; Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Cross-Over Studies; Female; Humans; Male; Middle Aged; Pilot Projects; Platelet Function Tests; Prospective Studies; Purinergic P2Y Receptor Antagonists; Ticagrelor; Ticlopidine

2015
Stopping antiplatelet medication before coronary artery bypass graft surgery: is there an optimal timing to minimize bleeding?
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2015, Volume: 48, Issue:4

    Topics: Aged; Aspirin; Blood Loss, Surgical; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Drug Therapy, Combination; Female; Humans; Linear Models; Male; Middle Aged; Multivariate Analysis; Platelet Aggregation Inhibitors; Platelet Transfusion; Postoperative Hemorrhage; Prospective Studies; Risk Assessment; Sensitivity and Specificity; Ticlopidine; Time Factors; Treatment Outcome; Withholding Treatment

2015
Temporal variability in the antiplatelet effects of clopidogrel and aspirin after elective drug-eluting stent implantation. An ADAPT-DES substudy.
    Thrombosis and haemostasis, 2015, Volume: 114, Issue:5

    Topics: Adenosine Diphosphate; Aged; Arachidonic Acid; Aspirin; Blood Vessel Prosthesis Implantation; Clopidogrel; Coronary Artery Disease; Drug-Eluting Stents; Elective Surgical Procedures; Female; Germany; Humans; Male; Middle Aged; Observer Variation; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Receptors, Purinergic P2Y12; Ticlopidine

2015
Increased platelet inhibition after switching from maintenance clopidogrel to prasugrel in Japanese patients with stable coronary artery disease.
    Circulation journal : official journal of the Japanese Circulation Society, 2015, Volume: 79, Issue:11

    Topics: Aged; Blood Platelets; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Drug Administration Schedule; Drug Substitution; Female; Genotype; Humans; Japan; Male; Middle Aged; Phenotype; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Prospective Studies; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Ticlopidine; Treatment Outcome

2015
Effects of CYP2C19 Polymorphism on Endothelial Function, Arterial Stiffness and Inflammation in Coronary Artery Disease Patients Under Clopidogrel Treatment.
    Current pharmaceutical design, 2015, Volume: 21, Issue:34

    Topics: Aged; Aged, 80 and over; Aspirin; Brachial Artery; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Drug Therapy, Combination; Endothelium, Vascular; Female; Genotype; Humans; Inflammation; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Real-Time Polymerase Chain Reaction; Ticlopidine; Vascular Stiffness

2015
Stopping or continuing clopidogrel 12 months after drug-eluting stent placement: the OPTIDUAL randomized trial.
    European heart journal, 2016, Jan-21, Volume: 37, Issue:4

    Topics: Acute Coronary Syndrome; Adult; Aftercare; Clopidogrel; Coronary Artery Disease; Drug Administration Schedule; Drug-Eluting Stents; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome

2016
Pharmacodynamic Effects When Clopidogrel is Given Before Cangrelor Discontinuation.
    Journal of interventional cardiology, 2015, Volume: 28, Issue:5

    Topics: Adenosine Monophosphate; Adult; Aged; Biological Availability; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug Interactions; Female; Humans; Male; Middle Aged; Outcome Assessment, Health Care; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine

2015
Prasugrel in Clopidogrel Nonresponders Undergoing Percutaneous Coronary Intervention: The RECLOSE-3 Study (REsponsiveness to CLOpidogrel and StEnt Thrombosis).
    JACC. Cardiovascular interventions, 2015, Volume: 8, Issue:12

    Topics: Aged; Aged, 80 and over; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug Resistance; Drug Substitution; Female; Historically Controlled Study; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Multivariate Analysis; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Predictive Value of Tests; Proportional Hazards Models; Risk Factors; Stents; Ticlopidine; Time Factors; Treatment Outcome

2015
Comparative effect on platelet function of a fixed-dose aspirin and clopidogrel combination versus separate formulations in patients with coronary artery disease: A phase IV, multicenter, prospective, 4-week non-inferiority trial.
    International journal of cardiology, 2016, Jan-01, Volume: 202

    Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Drug Combinations; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Ticlopidine; Treatment Outcome

2016
Platelet inhibition with ticagrelor versus clopidogrel in Hispanic patients with stable coronary artery disease with or without diabetes mellitus.
    Cardiovascular revascularization medicine : including molecular interventions, 2015, Volume: 16, Issue:8

    Topics: Adenosine; Administration, Oral; Aged; Chi-Square Distribution; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Cross-Over Studies; Diabetes Mellitus; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Hispanic or Latino; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Regression Analysis; Risk Assessment; Severity of Illness Index; Ticagrelor; Ticlopidine; Treatment Outcome; United States

2015
Antiplatelet Efficacy of Fixed-Dose Aspirin-Clopidogrel Combination in Patients with Stable Coronary Artery Disease Treated with Drug-Eluting Stent Implantation.
    Clinical drug investigation, 2015, Volume: 35, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Combinations; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Ticlopidine; Treatment Outcome; Young Adult

2015
Effects of dabigatran on the cellular and protein phase of coagulation in patients with coronary artery disease on dual antiplatelet therapy with aspirin and clopidogrel. Results from a prospective, randomised, double-blind, placebo-controlled study.
    Thrombosis and haemostasis, 2016, Volume: 115, Issue:3

    Topics: Administration, Oral; Aged; Anticoagulants; Aspirin; Blood Coagulation; Blood Platelets; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 Enzyme System; Dabigatran; Double-Blind Method; Electrodes; Female; Humans; Light; Male; Middle Aged; Nephelometry and Turbidimetry; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Thrombelastography; Thrombosis; Ticlopidine; Vitamin K

2016
A head-to-head pharmacodynamic comparison of prasugrel vs. ticagrelor after switching from clopidogrel in patients with coronary artery disease: results of a prospective randomized study.
    European heart journal, 2016, Sep-14, Volume: 37, Issue:35

    Topics: Adenosine; Blood Platelets; Clopidogrel; Coronary Artery Disease; Humans; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Prospective Studies; Ticagrelor; Ticlopidine

2016
Influence of smoking on the antiplatelet effect of clopidogrel differs according to clopidogrel dose: Insights from the GRAVITAS trial.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2017, Feb-01, Volume: 89, Issue:2

    Topics: Aged; Blood Platelets; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Drug-Eluting Stents; Female; Humans; Linear Models; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Percutaneous Coronary Intervention; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Risk Factors; Smoking; Ticlopidine; Time Factors; Treatment Outcome

2017
Effect of Modifying Antiplatelet Treatment to Ticagrelor in High-Risk Coronary Patients With Low Response to Clopidogrel (MATTIS).
    The Canadian journal of cardiology, 2016, Volume: 32, Issue:10

    Topics: Adenosine; Aged; Blood Platelets; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticagrelor; Ticlopidine; Troponin

2016
Association between insulin receptor substrate-1 polymorphisms and high platelet reactivity with clopidogrel therapy in coronary artery disease patients with type 2 diabetes mellitus.
    Cardiovascular diabetology, 2016, Mar-22, Volume: 15

    Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Diabetes Mellitus, Type 2; Drug Resistance; Drug Therapy, Combination; Female; Flow Cytometry; Gene Frequency; Haplotypes; Humans; Insulin Receptor Substrate Proteins; Male; Middle Aged; P-Selectin; Percutaneous Coronary Intervention; Pharmacogenetics; Phenotype; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Polymorphism, Single Nucleotide; Ticlopidine; Time Factors; Treatment Outcome

2016
Diabetes mellitus, CYP2C19 genotype, and response to escalating doses of clopidogrel. Insights from the ELEVATE-TIMI 56 Trial.
    Thrombosis and haemostasis, 2016, 07-04, Volume: 116, Issue:1

    Topics: Aged; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Dose-Response Relationship, Drug; Double-Blind Method; Female; Genotype; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Ticlopidine

2016
Comparison of dual antiplatelet therapy prescribed as one-pill versus two-pill regimen. A pooled analysis of individual patient data from the three MR-CAPCIS trials.
    Thrombosis and haemostasis, 2016, 07-04, Volume: 116, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Combinations; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Function Tests; Republic of Korea; Ticlopidine

2016
One-quarter standard-dose ticagrelor better than standard-dose clopidogrel in Chinese patients with stable coronary artery disease: A randomized, single-blind, crossover clinical study.
    International journal of cardiology, 2016, 07-15, Volume: 215

    Topics: Adenosine; Aged; China; Clopidogrel; Coronary Artery Disease; Cross-Over Studies; Female; Humans; Male; Middle Aged; Platelet Aggregation; Single-Blind Method; Ticagrelor; Ticlopidine; Treatment Outcome

2016
Impact of Anemia on Platelet Reactivity and Ischemic and Bleeding Risk: From the Assessment of Dual Antiplatelet Therapy With Drug-Eluting Stents Study.
    The American journal of cardiology, 2016, Jun-15, Volume: 117, Issue:12

    Topics: Aged; Anemia; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Drug-Eluting Stents; Europe; Female; Hemorrhage; Humans; Incidence; Male; Middle Aged; Myocardial Ischemia; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Registries; Risk Assessment; Risk Factors; Survival Rate; Ticlopidine; United States

2016
Prasugrel 5 mg inhibits platelet P-selectin and GPIIb-IIIa expression in very elderly and non elderly: results from the GENERATIONS trial, a pharmacodynamic study in stable CAD patients.
    Journal of thrombosis and thrombolysis, 2016, Volume: 42, Issue:3

    Topics: Acute Coronary Syndrome; Age Factors; Aged; Aged, 80 and over; Clopidogrel; Coronary Artery Disease; Humans; Middle Aged; P-Selectin; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prasugrel Hydrochloride; Ticlopidine

2016
Comparison of the antiplatelet effect of clopidogrel benzene sulfonate and clopidogrel hydrogen sulfate in stable coronary heart disease.
    Genetics and molecular research : GMR, 2016, Apr-25, Volume: 15, Issue:2

    Topics: Adult; Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Drug Combinations; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine

2016
Ticagrelor versus prasugrel in patients with high on-clopidogrel treatment platelet reactivity after PCI: The ISAR-ADAPT-PF study.
    Platelets, 2016, Volume: 27, Issue:8

    Topics: Adenosine; Adenosine Diphosphate; Aged; Blood Platelets; Clopidogrel; Comorbidity; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Risk Factors; Ticagrelor; Ticlopidine; Treatment Outcome

2016
Drug Interaction Between Clopidogrel and Ranitidine or Omeprazole in Stable Coronary Artery Disease: A Double-Blind, Double Dummy, Randomized Study.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2016, Volume: 16, Issue:4

    Topics: Aged; Blood Platelets; Clopidogrel; Coronary Artery Disease; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Omeprazole; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Proton Pump Inhibitors; Ranitidine; Ticlopidine

2016
Randomized evaluation of short-term dual antiplatelet therapy in patients with acute coronary syndrome treated with the COMBO dual therapy stent: rationale and design of the REDUCE trial.
    American heart journal, 2016, Volume: 178

    Topics: Acute Coronary Syndrome; Adenosine; Aspirin; Cause of Death; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Drug-Eluting Stents; Graft Occlusion, Vascular; Hemorrhage; Humans; Mortality; Myocardial Infarction; Myocardial Revascularization; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Stroke; Thrombosis; Ticagrelor; Ticlopidine; Time Factors

2016
Impact of Sex on 2-Year Clinical Outcomes in Patients Treated With 6-Month or 24-Month Dual-Antiplatelet Therapy Duration: A Pre-Specified Analysis From the PRODIGY Trial.
    JACC. Cardiovascular interventions, 2016, 09-12, Volume: 9, Issue:17

    Topics: Acute Coronary Syndrome; Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Coronary Thrombosis; Drug Administration Schedule; Drug Therapy, Combination; Female; Hemorrhage; Humans; Italy; Male; Middle Aged; Myocardial Infarction; Neointima; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Proportional Hazards Models; Risk Assessment; Risk Factors; Sex Factors; Stents; Stroke; Ticlopidine; Time Factors; Treatment Outcome

2016
Clopidogrel Versus Ticagrelor for Antiplatelet Maintenance in Diabetic Patients Treated With Percutaneous Coronary Intervention: Results of the CLOTILDIA Study (Clopidogrel High Dose Versus Ticagrelor for Antiplatelet Maintenance in Diabetic Patients).
    Circulation, 2016, Sep-13, Volume: 134, Issue:11

    Topics: Adenosine; Clopidogrel; Coronary Artery Disease; Diabetes Complications; Diabetes Mellitus, Type 2; Female; Humans; Male; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Ticagrelor; Ticlopidine

2016
Clinical outcomes of dual antiplatelet therapy after implantation of drug-eluting stents in patients with different cardiovascular risk factors.
    Clinical research in cardiology : official journal of the German Cardiac Society, 2017, Volume: 106, Issue:3

    Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Death, Sudden, Cardiac; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Incidence; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Republic of Korea; Risk Factors; Sirolimus; Ticlopidine; Time Factors

2017
Platelet reactivity and clinical outcomes in patients using CYP3A4-metabolized statins with clopidogrel in percutaneous coronary intervention.
    Heart and vessels, 2017, Volume: 32, Issue:6

    Topics: Aged; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Logistic Models; Male; Middle Aged; Multivariate Analysis; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Propensity Score; Prospective Studies; Republic of Korea; Ticlopidine; Treatment Outcome

2017
Randomized Angiographic and Intravascular Ultrasound Comparison of Dual-Antiplatelet Therapy vs Triple-Antiplatelet Therapy to Reduce Neointimal Tissue Proliferation in Diabetic Patients.
    The Journal of invasive cardiology, 2017, Volume: 29, Issue:3

    Topics: Aspirin; Cilostazol; Clopidogrel; Comorbidity; Coronary Angiography; Coronary Artery Disease; Coronary Restenosis; Diabetes Mellitus; Drug Therapy, Combination; Drug-Eluting Stents; Female; Hemorrhage; Humans; Male; Middle Aged; Neointima; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Sirolimus; Tetrazoles; Ticlopidine; Treatment Outcome

2017
Optimal aNtiplatelet pharmacotherapy guided by bedSIDE genetic or functional TESTing in elective PCI patients: A pilot study: ONSIDE TEST pilot.
    Cardiology journal, 2017, Volume: 24, Issue:3

    Topics: Adolescent; Adult; Aged; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Genotype; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Pilot Projects; Platelet Aggregation; Platelet Function Tests; Point-of-Care Systems; Prasugrel Hydrochloride; Preoperative Care; Retrospective Studies; Ticlopidine; Young Adult

2017
A randomized study assessing the impact of cilostazol on platelet function profiles in patients with diabetes mellitus and coronary artery disease on dual antiplatelet therapy: results of the OPTIMUS-2 study.
    European heart journal, 2008, Volume: 29, Issue:18

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Cilostazol; Clopidogrel; Coronary Artery Disease; Cross-Over Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Double-Blind Method; Female; Humans; Male; Middle Aged; Pilot Projects; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Tetrazoles; Ticlopidine; Treatment Outcome

2008
Effect of 150-mg vs 300-mg loading doses of clopidogrel on platelet function in Japanese patients undergoing coronary stent placement.
    Circulation journal : official journal of the Japanese Circulation Society, 2008, Volume: 72, Issue:8

    Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Asian People; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Dose-Response Relationship, Drug; Female; Humans; Japan; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Stents; Ticlopidine; Time Factors; Treatment Outcome

2008
Comparison of higher clopidogrel loading and maintenance dose to standard dose on platelet function and outcomes after percutaneous coronary intervention using drug-eluting stents.
    The American journal of cardiology, 2008, Aug-15, Volume: 102, Issue:4

    Topics: Angioplasty, Balloon, Coronary; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug Administration Schedule; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Single-Blind Method; Ticlopidine; Treatment Outcome

2008
Comparison of increased aspirin dose versus combined aspirin plus clopidogrel therapy in patients with diabetes mellitus and coronary heart disease and impaired antiplatelet response to low-dose aspirin.
    The American journal of cardiology, 2008, Aug-15, Volume: 102, Issue:4

    Topics: Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Failure

2008
Incidence and clinical impact of dual nonresponsiveness to aspirin and clopidogrel in patients with drug-eluting stents.
    Journal of the American College of Cardiology, 2008, Aug-26, Volume: 52, Issue:9

    Topics: Aged; Aged, 80 and over; Aspirin; Clopidogrel; Cohort Studies; Coronary Artery Disease; Drug Resistance, Multiple; Drug-Eluting Stents; Female; Graft Occlusion, Vascular; Humans; Incidence; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Radiography; Risk Factors; Ticlopidine

2008
Role of reticulated platelets and platelet size heterogeneity on platelet activity after dual antiplatelet therapy with aspirin and clopidogrel in patients with stable coronary artery disease.
    Journal of the American College of Cardiology, 2008, Aug-26, Volume: 52, Issue:9

    Topics: Aged; Aspirin; Cell Size; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Female; Flow Cytometry; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Count; Ticlopidine

2008
CYP2C19 and nongenetic factors predict poor responsiveness to clopidogrel loading dose after coronary stent implantation.
    Pharmacogenomics, 2008, Volume: 9, Issue:9

    Topics: Aged; Aged, 80 and over; Aryl Hydrocarbon Hydroxylases; Cardiac Surgical Procedures; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Female; Humans; Male; Middle Aged; Predictive Value of Tests; Risk Factors; Stents; Ticlopidine

2008
Comparison of four tests to assess inhibition of platelet function by clopidogrel in stable coronary artery disease patients.
    European heart journal, 2008, Volume: 29, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Double-Blind Method; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine

2008
Treatment of bifurcation lesions using dedicated bifurcation stents versus classic bare-metal stents. Randomized, controlled trial with 12-month angiographic follow up.
    The Journal of invasive cardiology, 2008, Volume: 20, Issue:10

    Topics: Adult; Aged; Anticoagulants; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Coronary Restenosis; Female; Fluoroscopy; Heparin; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Stents; Ticlopidine

2008
ADP-induced platelet aggregation frequently fails to detect impaired clopidogrel-responsiveness in patients with coronary artery disease compared to a P2Y12-specific assay.
    Thrombosis and haemostasis, 2008, Volume: 100, Issue:4

    Topics: Adenosine Diphosphate; Aged; Aspirin; Blood Platelets; Clopidogrel; Comorbidity; Coronary Artery Disease; Drug Resistance; Female; Flow Cytometry; Humans; Incidence; Male; P-Selectin; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Signal Transduction; Ticlopidine

2008
Greater reduction of platelet activation markers and platelet-monocyte aggregates by prasugrel compared to clopidogrel in stable coronary artery disease.
    Thrombosis and haemostasis, 2008, Volume: 100, Issue:4

    Topics: Adult; Aspirin; Biomarkers; Blood Platelets; Cell Communication; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Monocytes; P-Selectin; Piperazines; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prasugrel Hydrochloride; Thiophenes; Ticlopidine

2008
Tirofiban optimizes platelet inhibition for immediate percutaneous coronary intervention in high-risk acute coronary syndromes.
    Thrombosis and haemostasis, 2008, Volume: 100, Issue:4

    Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Myocardial Infarction; Necrosis; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine; Tirofiban; Treatment Outcome; Tyrosine

2008
Comparison of laboratory detection methods of aspirin resistance in coronary artery disease patients.
    International journal of laboratory hematology, 2010, Volume: 32, Issue:1 Pt 2

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Clinical Laboratory Techniques; Clopidogrel; Coronary Artery Disease; Drug Resistance; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine

2010
Comparison of collagen versus adenosine diphosphate in detecting antiplatelet effect in patients with coronary artery disease.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2009, Volume: 63, Issue:8

    Topics: Adenosine Diphosphate; Aged; Aspirin; Clopidogrel; Collagen; Coronary Artery Disease; Drug Resistance; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Prospective Studies; Ticlopidine; Treatment Outcome

2009
Population pharmacokinetics and pharmacodynamics of prasugrel and clopidogrel in aspirin-treated patients with stable coronary artery disease.
    Journal of pharmacokinetics and pharmacodynamics, 2008, Volume: 35, Issue:6

    Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Models, Biological; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Thiophenes; Ticlopidine

2008
Patients with poor responsiveness to thienopyridine treatment or with diabetes have lower levels of circulating active metabolite, but their platelets respond normally to active metabolite added ex vivo.
    Journal of the American College of Cardiology, 2008, Dec-09, Volume: 52, Issue:24

    Topics: Adult; Aged; Clopidogrel; Comorbidity; Coronary Artery Disease; Diabetes Complications; Double-Blind Method; Drug Resistance; Female; Humans; Male; Middle Aged; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Prevalence; Pyridines; Thiophenes; Ticlopidine; Treatment Failure; Treatment Outcome

2008
Bleeding risk associated with 1 year of dual antiplatelet therapy after percutaneous coronary intervention: Insights from the Clopidogrel for the Reduction of Events During Observation (CREDO) trial.
    American heart journal, 2009, Volume: 157, Issue:2

    Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Female; Gastrointestinal Hemorrhage; Hemorrhage; Humans; Incidence; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine; Time Factors

2009
Factors influencing clopidogrel efficacy in patients with stable coronary artery disease undergoing elective percutaneous coronary intervention: statin's advantage and the smoking "paradox".
    Journal of cardiovascular pharmacology, 2009, Volume: 53, Issue:5

    Topics: Age Factors; Aged; Angioplasty, Balloon, Coronary; Aspirin; Body Mass Index; Cell Adhesion Molecules; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Heparin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertension; Male; Microfilament Proteins; Phosphoproteins; Platelet Aggregation Inhibitors; Renal Insufficiency; Sex Factors; Smoking; Ticlopidine; Treatment Outcome

2009
A randomized controlled trial of a paclitaxel-eluting stent versus a similar bare-metal stent in saphenous vein graft lesions the SOS (Stenting of Saphenous Vein Grafts) trial.
    Journal of the American College of Cardiology, 2009, Mar-17, Volume: 53, Issue:11

    Topics: Aged; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Coronary Restenosis; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Paclitaxel; Platelet Aggregation Inhibitors; Saphenous Vein; Stents; Ticlopidine

2009
Considerable variability in platelet activity among patients with coronary artery disease in response to an increased maintenance dose of clopidogrel.
    Coronary artery disease, 2009, Volume: 20, Issue:3

    Topics: Adenosine Diphosphate; Aged; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2Y12; Ticlopidine; Time Factors

2009
Insights into the interpretation of light transmission aggregometry for evaluation of platelet aggregation inhibition by clopidogrel.
    Thrombosis research, 2009, Volume: 124, Issue:5

    Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Clopidogrel; Coronary Artery Disease; Double-Blind Method; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Ticlopidine

2009
Paclitaxel- versus sirolimus-eluting stents for unprotected left main coronary artery disease.
    Journal of the American College of Cardiology, 2009, May-12, Volume: 53, Issue:19

    Topics: Aged; Angioplasty, Balloon, Coronary; Clopidogrel; Confidence Intervals; Coronary Angiography; Coronary Artery Disease; Coronary Restenosis; Drug-Eluting Stents; Female; Humans; Immunosuppressive Agents; Incidence; Male; Myocardial Infarction; Paclitaxel; Platelet Aggregation Inhibitors; Risk; Sirolimus; Ticlopidine; Tubulin Modulators

2009
Clopidogrel 150 mg/day to overcome low responsiveness in patients undergoing elective percutaneous coronary intervention: results from the VASP-02 (Vasodilator-Stimulated Phosphoprotein-02) randomized study.
    JACC. Cardiovascular interventions, 2008, Volume: 1, Issue:6

    Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Blood Platelets; Cell Adhesion Molecules; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance; Drug Therapy, Combination; Europe; Female; Hemorrhage; Humans; Male; Microfilament Proteins; Middle Aged; Odds Ratio; Phosphoproteins; Phosphorylation; Platelet Aggregation Inhibitors; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Risk Assessment; Stents; Ticlopidine; Time Factors

2008
The pharmacogenetics and pharmacodynamics of clopidogrel response: an analysis from the PRINC (Plavix Response in Coronary Intervention) trial.
    JACC. Cardiovascular interventions, 2008, Volume: 1, Issue:6

    Topics: Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood Platelets; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance; Gene Frequency; Genotype; Humans; Phenotype; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Stents; Thrombosis; Ticlopidine; Time Factors

2008
The effects of aspirin and clopidogrel response on myonecrosis after percutaneous coronary intervention: a BRIEF-PCI (Brief Infusion of Intravenous Eptifibatide Following Successful Percutaneous Coronary Intervention) trial substudy.
    JACC. Cardiovascular interventions, 2008, Volume: 1, Issue:6

    Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug Administration Schedule; Drug Resistance; Drug Therapy, Combination; Eptifibatide; Female; Heart Diseases; Hemorrhage; Humans; Infusions, Intravenous; Male; Middle Aged; Myocardial Infarction; Necrosis; Peptides; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prospective Studies; Ticlopidine; Time Factors; Treatment Outcome

2008
Glycoprotein IIb/IIIa inhibitors improve outcome after coronary stenting in clopidogrel nonresponders: a prospective, randomized study.
    JACC. Cardiovascular interventions, 2008, Volume: 1, Issue:6

    Topics: Abciximab; Aged; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Disease-Free Survival; Drug Resistance; Drug Therapy, Combination; Female; Hemorrhage; Humans; Immunoglobulin Fab Fragments; Kaplan-Meier Estimate; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prospective Studies; Risk Assessment; Stents; Ticlopidine; Time Factors; Treatment Outcome

2008
Safety and efficacy of biodegradable polymer-coated sirolimus-eluting stents in "real-world" practice: 18-month clinical and 9-month angiographic outcomes.
    JACC. Cardiovascular interventions, 2009, Volume: 2, Issue:4

    Topics: Aged; Angioplasty, Balloon, Coronary; Asia; Aspirin; Cardiovascular Agents; Clopidogrel; Coated Materials, Biocompatible; Coronary Angiography; Coronary Artery Disease; Coronary Restenosis; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Platelet Aggregation Inhibitors; Polymers; Product Surveillance, Postmarketing; Prospective Studies; Prosthesis Design; Registries; Risk Assessment; Sirolimus; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome

2009
Intensifying platelet inhibition with tirofiban in poor responders to aspirin, clopidogrel, or both agents undergoing elective coronary intervention: results from the double-blind, prospective, randomized Tailoring Treatment with Tirofiban in Patients Sho
    Circulation, 2009, Jun-30, Volume: 119, Issue:25

    Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Blood Platelets; Clopidogrel; Combined Modality Therapy; Coronary Artery Disease; Coronary Thrombosis; Double-Blind Method; Drug Resistance; Female; Humans; Incidence; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Prospective Studies; Risk Factors; Ticlopidine; Tirofiban; Tyrosine

2009
High loading dose of clopidogrel is unable to satisfactorily inhibit platelet reactivity in patients with glycoprotein IIIA gene polymorphism: a genetic substudy of PRAGUE-8 trial.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2009, Volume: 20, Issue:4

    Topics: Adenosine Diphosphate; Aged; Antigens, Human Platelet; Clopidogrel; Coronary Artery Disease; Female; Humans; Integrin beta3; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Ticlopidine; Time Factors

2009
Influence of statin treatment on platelet inhibition by clopidogrel - a randomized comparison of rosuvastatin, atorvastatin and simvastatin co-treatment.
    Journal of internal medicine, 2009, Volume: 266, Issue:5

    Topics: Aged; Anticholesteremic Agents; Atorvastatin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Double-Blind Method; Drug Interactions; Female; Fluorobenzenes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Simvastatin; Sulfonamides; Ticlopidine

2009
Relation of genetic polymorphisms in the cytochrome P450 gene with clopidogrel resistance after drug-eluting stent implantation in Koreans.
    The American journal of cardiology, 2009, Jul-01, Volume: 104, Issue:1

    Topics: Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Cilostazol; Clopidogrel; Confidence Intervals; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Drug Resistance; Female; Humans; Korea; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Tetrazoles; Ticlopidine

2009
Thrombin formation and platelet activation at the site of vascular injury in patients with coronary artery disease treated with clopidogrel combined with aspirin.
    Kardiologia polska, 2009, Volume: 67, Issue:6

    Topics: Aspirin; Biomarkers; CD40 Ligand; Clopidogrel; Coronary Artery Disease; Drug Administration Schedule; Drug Therapy, Combination; Humans; Lacerations; Male; Middle Aged; P-Selectin; Platelet Activation; Platelet Aggregation Inhibitors; Punctures; Skin; Thrombin; Ticlopidine; Veins

2009
Week-long high-maintenance dose clopidogrel regimen achieves better platelet aggregation inhibition than a standard loading dose before percutaneous coronary intervention: results of a double-blind, randomized clinical trial.
    Journal of interventional cardiology, 2009, Volume: 22, Issue:4

    Topics: Analysis of Variance; Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Artery Disease; Double-Blind Method; Female; Humans; Logistic Models; Male; Middle Aged; Myocardial Ischemia; Platelet Aggregation Inhibitors; Ticlopidine; Time Factors

2009
Long term efficacy of abciximab bolus-only compared to abciximab bolus and infusion after transradial coronary stenting.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2009, Dec-01, Volume: 74, Issue:7

    Topics: Abciximab; Aged; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Female; Hemorrhage; Humans; Immunoglobulin Fab Fragments; Infusions, Parenteral; Injections; Length of Stay; Logistic Models; Male; Middle Aged; Myocardial Infarction; Patient Discharge; Platelet Aggregation Inhibitors; Proportional Hazards Models; Radial Artery; Risk Assessment; Risk Factors; Stents; Ticlopidine; Time Factors; Treatment Outcome

2009
The effect of elinogrel on high platelet reactivity during dual antiplatelet therapy and the relation to CYP2C19*2 genotype: first experience in patients.
    Journal of thrombosis and haemostasis : JTH, 2010, Volume: 8, Issue:1

    Topics: Adenosine Diphosphate; Administration, Oral; Aged; Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Aspirin; Blood Coagulation; Blood Platelets; Cell Adhesion Molecules; Clopidogrel; Collagen; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Drug Therapy, Combination; Female; Gene Frequency; Genotype; Humans; Male; Microfilament Proteins; Middle Aged; Phenotype; Phosphoproteins; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Purinergic P2 Receptor Antagonists; Quinazolinones; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Stents; Sulfonamides; Thrombelastography; Ticlopidine

2010
Impact of final activated clotting time after transradial coronary stenting with maximal antiplatelet therapy.
    The American journal of cardiology, 2009, Nov-01, Volume: 104, Issue:9

    Topics: Abciximab; Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Anticoagulants; Aspirin; Clopidogrel; Coronary Artery Disease; Creatine Kinase, MB Form; Female; Follow-Up Studies; Hematoma; Hemorrhage; Heparin; Humans; Immunoglobulin Fab Fragments; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Count; Premedication; Retreatment; Sex Factors; Stents; Ticlopidine; Troponin T; Whole Blood Coagulation Time

2009
Design and rationale of the WOEST trial: What is the Optimal antiplatElet and anticoagulant therapy in patients with oral anticoagulation and coronary StenTing (WOEST).
    American heart journal, 2009, Volume: 158, Issue:5

    Topics: Administration, Oral; Anticoagulants; Aspirin; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Treatment Outcome

2009
Randomized double-blind assessment of the ONSET and OFFSET of the antiplatelet effects of ticagrelor versus clopidogrel in patients with stable coronary artery disease: the ONSET/OFFSET study.
    Circulation, 2009, Dec-22, Volume: 120, Issue:25

    Topics: Adenosine; Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Phosphoproteins; Phosphorylation; Platelet Aggregation Inhibitors; Ticagrelor; Ticlopidine; Treatment Outcome

2009
Clopidogrel affects leukocyte dependent platelet aggregation by P2Y12 expressing leukocytes.
    Basic research in cardiology, 2010, Volume: 105, Issue:3

    Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Female; Humans; Leukocytes; Male; Obesity; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Stents; Ticlopidine

2010
Reasonable duration of Clopidogrel use after drug-eluting stent implantation in Korean patients.
    The American journal of cardiology, 2009, Dec-15, Volume: 104, Issue:12

    Topics: Aged; Clopidogrel; Coronary Artery Disease; Drug-Eluting Stents; Female; Humans; Korea; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine; Time Factors; Treatment Outcome

2009
In-hospital outcomes of contemporary percutaneous coronary intervention in patients with chronic total occlusion insights from the J-CTO Registry (Multicenter CTO Registry in Japan).
    JACC. Cardiovascular interventions, 2010, Volume: 3, Issue:2

    Topics: Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Female; Humans; Inpatients; Japan; Length of Stay; Male; Platelet Aggregation Inhibitors; Prospective Studies; Registries; Stents; Ticlopidine; Time Factors; Treatment Outcome

2010
Comparison of platelet function tests in predicting clinical outcome in patients undergoing coronary stent implantation.
    JAMA, 2010, Feb-24, Volume: 303, Issue:8

    Topics: Aged; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Function Tests; Postoperative Complications; Predictive Value of Tests; Prospective Studies; Stents; Stroke; Thrombosis; Ticlopidine; Treatment Outcome

2010
Response to ticagrelor in clopidogrel nonresponders and responders and effect of switching therapies: the RESPOND study.
    Circulation, 2010, Mar-16, Volume: 121, Issue:10

    Topics: Adenosine; Aged; Cell Adhesion Molecules; Clopidogrel; Coronary Artery Disease; Cross-Over Studies; Double-Blind Method; Female; Flow Cytometry; Humans; Male; Microfilament Proteins; Middle Aged; Phosphoproteins; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2Y12; Ticagrelor; Ticlopidine

2010
Effects of polyunsaturated omega-3 fatty acids on responsiveness to dual antiplatelet therapy in patients undergoing percutaneous coronary intervention: the OMEGA-PCI (OMEGA-3 fatty acids after pci to modify responsiveness to dual antiplatelet therapy) st
    Journal of the American College of Cardiology, 2010, Apr-20, Volume: 55, Issue:16

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Blood Proteins; Cell Adhesion Molecules; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Fatty Acids, Omega-3; Female; Follow-Up Studies; Humans; Male; Microfilament Proteins; Middle Aged; Phosphoproteins; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Prognosis; Prospective Studies; Ticlopidine; Treatment Outcome

2010
Pantoprazole does not influence the antiplatelet effect of clopidogrel-a whole blood aggregometry study after coronary stenting.
    Journal of cardiovascular pharmacology, 2010, Volume: 56, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Interactions; Esomeprazole; Female; Humans; Male; Middle Aged; Multivariate Analysis; Omeprazole; Pantoprazole; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Proton Pump Inhibitors; Regression Analysis; Stents; Ticlopidine

2010
Ticagrelor, a new antiplatelet agent, for prevention of ischemic events in patients with coronary artery disease.
    Current neurology and neuroscience reports, 2010, Volume: 10, Issue:1

    Topics: Adenosine; Clopidogrel; Coronary Artery Disease; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Ischemia; Male; Platelet Aggregation Inhibitors; Proportional Hazards Models; Ticagrelor; Ticlopidine; Time Factors; Treatment Outcome

2010
The impact of generic clopidogrel bisulfate on platelet inhibition in patients with coronary artery stents: results of the ACCEL-GENERIC study.
    The Korean journal of internal medicine, 2010, Volume: 25, Issue:2

    Topics: Aged; Angioplasty, Balloon, Coronary; Clopidogrel; Combined Modality Therapy; Coronary Artery Disease; Drug-Eluting Stents; Drugs, Generic; Female; Follow-Up Studies; Humans; Male; Middle Aged; Patient Compliance; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Ticlopidine

2010
Rationale and design of the randomized, double-blind trial testing INtraveNous and Oral administration of elinogrel, a selective and reversible P2Y(12)-receptor inhibitor, versus clopidogrel to eVAluate Tolerability and Efficacy in nonurgent Percutaneous
    American heart journal, 2010, Volume: 160, Issue:1

    Topics: Administration, Oral; Adolescent; Adult; Aged; Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Artery Disease; Double-Blind Method; Drug Tolerance; Female; Follow-Up Studies; Humans; Injections, Intravenous; Male; Middle Aged; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Quinazolinones; Receptors, Purinergic P2Y12; Sulfonamides; Ticlopidine; Time Factors; Treatment Outcome; Troponin; Young Adult

2010
Lack of evidence for pleiotropic effects of clopidogrel on endothelial function and inflammation in patients with stable coronary artery disease: results of the double-blind, randomized CASSANDRA study.
    Clinical research in cardiology : official journal of the German Cardiac Society, 2011, Volume: 100, Issue:1

    Topics: Clopidogrel; Comorbidity; Coronary Artery Disease; Double-Blind Method; Endothelium, Vascular; Evidence-Based Medicine; Female; Germany; Humans; Incidence; Male; Middle Aged; Platelet Aggregation Inhibitors; Risk Assessment; Risk Factors; Ticlopidine; Treatment Outcome; Vasculitis

2011
A randomised determination of the Effect of Fluvastatin and Atorvastatin on top of dual antiplatelet treatment on platelet aggregation after implantation of coronary drug-eluting stents. The EFA-Trial.
    Thrombosis and haemostasis, 2010, Volume: 104, Issue:3

    Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Atorvastatin; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Drug Interactions; Drug Therapy, Combination; Drug-Eluting Stents; Fatty Acids, Monounsaturated; Female; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Prosthesis Design; Pyrroles; Switzerland; Ticlopidine; Time Factors; Treatment Outcome

2010
Intra-individual variability in clopidogrel responsiveness in coronary artery disease patients under long term therapy.
    Platelets, 2010, Volume: 21, Issue:7

    Topics: Aspirin; Blood Platelets; Cell Adhesion Molecules; Clopidogrel; Coronary Artery Disease; Drug-Eluting Stents; Female; Humans; Individuality; Male; Microfilament Proteins; Middle Aged; Phosphoproteins; Platelet Aggregation Inhibitors; Prospective Studies; Ticlopidine

2010
Background, incidence, and predictors of antiplatelet therapy discontinuation during the first year after drug-eluting stent implantation.
    Circulation, 2010, Sep-07, Volume: 122, Issue:10

    Topics: Aged; Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Artery Disease; Drug Administration Schedule; Drug-Eluting Stents; Female; Follow-Up Studies; Hemorrhage; Humans; Incidence; Male; Medication Adherence; Middle Aged; Multivariate Analysis; Patient Readmission; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Predictive Value of Tests; Prospective Studies; Renal Insufficiency; Self Medication; Thrombosis; Ticlopidine

2010
Comparison between the effect of omeprazole and rabeprazole on the antiplatelet action of clopidogrel.
    Circulation journal : official journal of the Japanese Circulation Society, 2010, Volume: 74, Issue:10

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenosine Diphosphate; Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Interactions; Enzyme Inhibitors; Female; Humans; Male; Middle Aged; Omeprazole; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabeprazole; Ticlopidine; Treatment Outcome

2010
Clopidogrel with or without omeprazole in coronary artery disease.
    The New England journal of medicine, 2010, Nov-11, Volume: 363, Issue:20

    Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Drug Interactions; Drug Therapy, Combination; Female; Gastrointestinal Hemorrhage; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Omeprazole; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Ticlopidine

2010
Aspirin plus clopidogrel therapy increases early venous graft patency after coronary artery bypass surgery a single-center, randomized, controlled trial.
    Journal of the American College of Cardiology, 2010, Nov-09, Volume: 56, Issue:20

    Topics: Administration, Oral; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Bypass; Coronary Artery Disease; Drug Therapy, Combination; Electrocardiography; Female; Follow-Up Studies; Graft Occlusion, Vascular; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Saphenous Vein; Ticlopidine; Time Factors; Tomography, X-Ray Computed; Treatment Outcome; Vascular Patency

2010
First analysis of the relation between CYP2C19 genotype and pharmacodynamics in patients treated with ticagrelor versus clopidogrel: the ONSET/OFFSET and RESPOND genotype studies.
    Circulation. Cardiovascular genetics, 2010, Volume: 3, Issue:6

    Topics: Adenosine; Aged; Aryl Hydrocarbon Hydroxylases; Aspirin; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Double-Blind Method; Genotype; Humans; Male; Middle Aged; Pharmacokinetics; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Purinergic P2Y Receptor Antagonists; Ticagrelor; Ticlopidine

2010
Effect of omeprazole on the concentration of interleukin-6 and transforming growth factor-β1 in patients receiving dual antiplatelet therapy after percutaneous coronary intervention.
    European cytokine network, 2010, Volume: 21, Issue:4

    Topics: Aged; Anti-Ulcer Agents; Aspirin; Biomarkers; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Drug Therapy, Combination; Female; Follow-Up Studies; Gene Expression Regulation; Humans; Interleukin-6; Male; Middle Aged; Omeprazole; Platelet Aggregation Inhibitors; Predictive Value of Tests; Ticlopidine; Transforming Growth Factor beta1; Treatment Outcome

2010
Pretreatment with different loading doses of clopidogrel influences P-selectin levels in patients undergoing percutaneous coronary intervention: results from the ARMYDA-2 (antiplatelet therapy for reduction of myocardial damage during angioplasty) SELECT
    Journal of cardiovascular medicine (Hagerstown, Md.), 2011, Volume: 12, Issue:3

    Topics: Aged; Analysis of Variance; Angioplasty, Balloon, Coronary; Biomarkers; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Double-Blind Method; Drug Administration Schedule; Female; Heart Diseases; Humans; Italy; Male; Middle Aged; P-Selectin; Platelet Aggregation Inhibitors; Prospective Studies; Ticlopidine; Time Factors; Treatment Outcome; Troponin I

2011
Aspirin plus clopidogrel versus aspirin alone after coronary artery bypass grafting: the clopidogrel after surgery for coronary artery disease (CASCADE) Trial.
    Circulation, 2010, Dec-21, Volume: 122, Issue:25

    Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Double-Blind Method; Drug Therapy, Combination; Female; Hemorrhage; Humans; Hyperplasia; Incidence; Male; Middle Aged; Platelet Aggregation Inhibitors; Saphenous Vein; Ticlopidine; Treatment Outcome; Tunica Intima; Ultrasonography, Interventional

2010
A pharmacodynamic comparison of prasugrel vs. high-dose clopidogrel in patients with type 2 diabetes mellitus and coronary artery disease: results of the Optimizing anti-Platelet Therapy In diabetes MellitUS (OPTIMUS)-3 Trial.
    European heart journal, 2011, Volume: 32, Issue:7

    Topics: Adolescent; Adult; Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Cross-Over Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Double-Blind Method; Female; Humans; Male; Middle Aged; Piperazines; Platelet Activation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Prospective Studies; Thiophenes; Ticlopidine; Treatment Outcome; Young Adult

2011
Safety of clopidogrel in older patients: a nonrandomized, parallel-group, controlled, two-centre study.
    Drugs & aging, 2011, Feb-01, Volume: 28, Issue:2

    Topics: Acute Coronary Syndrome; Administration, Cutaneous; Age Factors; Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Prospective Studies; Stents; Stroke; Thrombocytopenia; Ticlopidine; Treatment Outcome

2011
A randomized, double-blind, multicenter comparison study of triple antiplatelet therapy with dual antiplatelet therapy to reduce restenosis after drug-eluting stent implantation in long coronary lesions: results from the DECLARE-LONG II (Drug-Eluting Sten
    Journal of the American College of Cardiology, 2011, Mar-15, Volume: 57, Issue:11

    Topics: Aged; Aspirin; Cilostazol; Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Double-Blind Method; Drug Therapy, Combination; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Radiography; Tetrazoles; Ticlopidine; Treatment Outcome

2011
Reduced thrombin formation and altered fibrin clot properties induced by polyunsaturated omega-3 fatty acids on top of dual antiplatelet therapy in patients undergoing percutaneous coronary intervention (OMEGA-PCI clot).
    Arteriosclerosis, thrombosis, and vascular biology, 2011, Volume: 31, Issue:7

    Topics: Aged; Analysis of Variance; Angioplasty, Balloon, Coronary; Aspirin; Biomarkers; Blood Coagulation; C-Reactive Protein; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Dinoprost; Double-Blind Method; Down-Regulation; Drug Therapy, Combination; Fatty Acids, Omega-3; Female; Fibrin; Humans; Linear Models; Male; Middle Aged; Oxidative Stress; Peptide Fragments; Platelet Aggregation; Platelet Aggregation Inhibitors; Poland; Prospective Studies; Prothrombin; Thrombin; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome

2011
Variability in on-treatment platelet reactivity explained by CYP2C19*2 genotype is modest in clopidogrel pretreated patients undergoing coronary stenting.
    Heart (British Cardiac Society), 2011, Volume: 97, Issue:15

    Topics: Aged; Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Cytochrome P-450 CYP2C19; DNA; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Genotype; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Polymerase Chain Reaction; Polymorphism, Genetic; Preoperative Period; Prognosis; Prospective Studies; Stents; Ticlopidine

2011
Comparison of titanium-nitride-oxide-coated stents with zotarolimus-eluting stents for coronary revascularization a randomized controlled trial.
    JACC. Cardiovascular interventions, 2011, Volume: 4, Issue:6

    Topics: Aged; Angioplasty, Balloon, Coronary; Clopidogrel; Confidence Intervals; Coronary Angiography; Coronary Artery Disease; Drug-Eluting Stents; Female; Humans; Logistic Models; Male; Middle Aged; Myocardial Reperfusion; Platelet Aggregation Inhibitors; Risk Factors; Sirolimus; Statistics as Topic; Statistics, Nonparametric; Switzerland; Ticlopidine; Titanium

2011
Earlier recovery of platelet function after discontinuation of treatment with ticagrelor compared with clopidogrel in patients with high antiplatelet responses.
    Journal of thrombosis and haemostasis : JTH, 2011, Volume: 9, Issue:9

    Topics: Adenosine; Adult; Aged; Aged, 80 and over; Blood Platelets; Clopidogrel; Coronary Artery Disease; Double-Blind Method; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Function Tests; Purinergic P2Y Receptor Antagonists; Ticagrelor; Ticlopidine; Time Factors

2011
The effect of ticagrelor versus clopidogrel on high on-treatment platelet reactivity: combined analysis of the ONSET/OFFSET and RESPOND studies.
    American heart journal, 2011, Volume: 162, Issue:1

    Topics: Adenosine; Administration, Oral; Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Retrospective Studies; Ticagrelor; Ticlopidine; Time Factors; Treatment Outcome

2011
Effect of clopidogrel withdrawal on platelet reactivity and vascular inflammatory biomarkers 1 year after drug-eluting stent implantation: results of the prospective, single-centre CESSATION study.
    Heart (British Cardiac Society), 2011, Volume: 97, Issue:20

    Topics: Aged; Biomarkers; C-Reactive Protein; CD40 Ligand; Clopidogrel; Coronary Artery Disease; Coronary Vessels; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Inflammation; Interleukin-6; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Prognosis; Prospective Studies; Thromboxane B2; Ticlopidine; Time Factors; Withholding Treatment

2011
CYP2C19*2 and other genetic variants affecting platelet response to clopidogrel in patients undergoing percutaneous coronary intervention.
    Thrombosis research, 2012, Volume: 129, Issue:4

    Topics: Clopidogrel; Comorbidity; Coronary Artery Disease; Cytokines; Female; Genetic Predisposition to Disease; Greece; Humans; Male; Platelet Activation; Platelet Aggregation Inhibitors; Prevalence; Stents; Thrombosis; Ticlopidine; Treatment Outcome

2012
Impact of pentoxifylline on platelet function profiles in patients with type 2 diabetes mellitus and coronary artery disease on dual antiplatelet therapy with aspirin and clopidogrel.
    JACC. Cardiovascular interventions, 2011, Volume: 4, Issue:8

    Topics: Aged; Aspirin; Blood Platelets; Cell Adhesion Molecules; Clopidogrel; Coronary Artery Disease; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Florida; Humans; Male; Microfilament Proteins; Middle Aged; Pentoxifylline; Phosphodiesterase Inhibitors; Phosphoproteins; Phosphorylation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Receptors, Purinergic P2Y12; Ticlopidine; Time Factors; Treatment Outcome

2011
Impact of smoking on antiplatelet effect of clopidogrel and prasugrel after loading dose and on maintenance therapy.
    American heart journal, 2011, Volume: 162, Issue:3

    Topics: Aged; Blood Platelets; Clopidogrel; Coronary Artery Disease; Cross-Over Studies; Cytochrome P-450 CYP1A2; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Male; Middle Aged; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Risk Factors; Smoking; Thiophenes; Ticlopidine; Time Factors; Treatment Outcome

2011
Prasugrel overcomes high on-clopidogrel platelet reactivity in chronic coronary artery disease patients more effectively than high dose (150 mg) clopidogrel.
    American heart journal, 2011, Volume: 162, Issue:4

    Topics: Aged; Chronic Disease; Clopidogrel; Coronary Artery Disease; Cross-Over Studies; Female; Humans; Male; Middle Aged; Piperazines; Platelet Activation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Prospective Studies; Purinergic P2Y Receptor Antagonists; Single-Blind Method; Thiophenes; Ticlopidine; Treatment Outcome

2011
Incidence, predictors, and 30-day outcomes of new-onset atrial fibrillation after primary percutaneous coronary intervention: insight into the RISK-PCI trial.
    Coronary artery disease, 2012, Volume: 23, Issue:1

    Topics: Aged; Angioplasty, Balloon, Coronary; Atrial Fibrillation; Chi-Square Distribution; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Female; Hospital Mortality; Humans; Incidence; Kaplan-Meier Estimate; Logistic Models; Male; Middle Aged; Odds Ratio; Platelet Aggregation Inhibitors; Risk Assessment; Risk Factors; Serbia; Ticlopidine; Time Factors; Treatment Outcome

2012
Platelet reactivity in patients with chronic kidney disease receiving adjunctive cilostazol compared with a high-maintenance dose of clopidogrel: results of the effect of platelet inhibition according to clopidogrel dose in patients with chronic kidney di
    American heart journal, 2011, Volume: 162, Issue:6

    Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Chronic Disease; Cilostazol; Clopidogrel; Coronary Artery Disease; Female; Humans; Kidney Diseases; Male; Middle Aged; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Renal Dialysis; Tetrazoles; Ticlopidine

2011
Pharmacodynamic assessment of a novel P2Y12 receptor antagonist in Japanese patients with coronary artery disease undergoing elective percutaneous coronary intervention.
    Thrombosis research, 2012, Volume: 129, Issue:5

    Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Double-Blind Method; Female; Humans; Japan; Male; Middle Aged; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Thiophenes; Ticlopidine; Young Adult

2012
Endothelial progenitor cell mobilization and platelet microparticle release are influenced by clopidogrel plasma levels in stable coronary artery disease.
    Circulation journal : official journal of the Japanese Circulation Society, 2012, Volume: 76, Issue:3

    Topics: Adult; Aged; Blood Platelets; Cell Movement; Cell-Derived Microparticles; Clopidogrel; Coronary Artery Disease; Endothelial Cells; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Protective Agents; Purinergic P2Y Receptor Antagonists; Stem Cells; Ticlopidine

2012
Description of response to aspirin and clopidogrel in outpatients with coronary artery disease using multiple electrode impedance aggregometry.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2012, Volume: 18, Issue:4

    Topics: Adult; Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Placental Function Tests; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine

2012
A prospective randomized trial comparing the recovery of platelet function after loading dose administration of prasugrel or clopidogrel.
    Platelets, 2013, Volume: 24, Issue:1

    Topics: Aged; Blood Platelets; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Thiophenes; Ticlopidine; Treatment Outcome

2013
Pharmacodynamic effects of adjunctive cilostazol therapy in patients with coronary artery disease on dual antiplatelet therapy: impact of high on-treatment platelet reactivity and diabetes mellitus status.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2013, Jan-01, Volume: 81, Issue:1

    Topics: Aged; Aspirin; Blood Platelets; Cilostazol; Clopidogrel; Coronary Artery Disease; Cross-Over Studies; Diabetic Angiopathies; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Radiography; Risk Assessment; Statistics, Nonparametric; Survival Analysis; Tetrazoles; Ticlopidine; Treatment Outcome

2013
[High maintenance dose of clopidogrel improves long-term clinical outcomes in patients with elective percutaneous coronary intervention].
    Zhonghua yi xue za zhi, 2012, Feb-14, Volume: 92, Issue:6

    Topics: Aged; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prospective Studies; Ticlopidine; Treatment Outcome

2012
Accelerated platelet inhibition by switching from atorvastatin to a non-CYP3A4-metabolized statin in patients with high platelet reactivity (ACCEL-STATIN) study.
    European heart journal, 2012, Volume: 33, Issue:17

    Topics: Adenosine Diphosphate; Aspirin; Atorvastatin; Calcium Channel Blockers; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP3A; Drug Substitution; Drug Therapy, Combination; Female; Fluorobenzenes; Genotype; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Pravastatin; Prospective Studies; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Sulfonamides; Ticlopidine

2012
Pharmacokinetics and pharmacodynamics of ticagrelor in patients with stable coronary artery disease: results from the ONSET-OFFSET and RESPOND studies.
    Clinical pharmacokinetics, 2012, Jun-01, Volume: 51, Issue:6

    Topics: Adenosine; Aged; Clopidogrel; Coronary Artery Disease; Double-Blind Method; Drug Interactions; Female; Humans; Male; Middle Aged; Platelet Aggregation; Purinergic P2Y Receptor Antagonists; Ticagrelor; Ticlopidine

2012
A randomized trial of prasugrel versus clopidogrel in patients with high platelet reactivity on clopidogrel after elective percutaneous coronary intervention with implantation of drug-eluting stents: results of the TRIGGER-PCI (Testing Platelet Reactivity
    Journal of the American College of Cardiology, 2012, Jun-12, Volume: 59, Issue:24

    Topics: Aged; Angioplasty, Balloon, Coronary; Blood Platelets; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Thiophenes; Ticlopidine

2012
Rationale and design of the Cangrelor versus standard therapy to acHieve optimal Management of Platelet InhibitiON PHOENIX trial.
    American heart journal, 2012, Volume: 163, Issue:5

    Topics: Adenosine Monophosphate; Adult; Aged; Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Infusions, Intravenous; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Risk Assessment; Survival Analysis; Ticlopidine; Treatment Outcome

2012
Polyunsaturated omega-3 fatty acids improve responsiveness to clopidogrel after percutaneous coronary intervention in patients with cytochrome P450 2C19 loss-of-function polymorphism.
    Kardiologia polska, 2012, Volume: 70, Issue:5

    Topics: Administration, Cutaneous; Aged; Aryl Hydrocarbon Hydroxylases; Aspirin; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Double-Blind Method; Drug Synergism; Fatty Acids, Omega-3; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Prospective Studies; Ticlopidine

2012
Relation between clopidogrel active metabolite levels and different platelet aggregation methods in patients receiving clopidogrel and aspirin.
    Journal of thrombosis and thrombolysis, 2012, Volume: 34, Issue:4

    Topics: Adenosine Diphosphate; Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prodrugs; Ticlopidine; Time Factors

2012
Tranexamic Acid in on-pump coronary artery bypass grafting without clopidogrel and aspirin cessation: randomized trial and 1-year follow-up.
    The Annals of thoracic surgery, 2013, Volume: 95, Issue:3

    Topics: Antifibrinolytic Agents; Aspirin; Blood Loss, Surgical; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Ticlopidine; Time Factors; Tranexamic Acid; Treatment Outcome

2013
Pharmacodynamic effect of switching therapy in patients with high on-treatment platelet reactivity and genotype variation with high clopidogrel Dose versus prasugrel: the RESET GENE trial.
    Circulation. Cardiovascular interventions, 2012, Volume: 5, Issue:5

    Topics: Aged; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Blood Platelets; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Cross-Over Studies; Cytochrome P-450 CYP2C19; Drug Substitution; Female; Genotype; Humans; Male; Middle Aged; Myocardial Ischemia; Percutaneous Coronary Intervention; Phenotype; Piperazines; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Prospective Studies; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Rome; Thiophenes; Ticlopidine; Treatment Outcome

2012
Lack of association between clopidogrel responsiveness tested using point-of-care assay and prognosis of patients with coronary artery disease.
    Journal of thrombosis and thrombolysis, 2013, Volume: 36, Issue:1

    Topics: Aged; Aged, 80 and over; Clopidogrel; Coronary Artery Disease; Disease-Free Survival; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Point-of-Care Systems; Prospective Studies; Stroke; Survival Rate; Ticlopidine

2013
Biological efficacy of twice daily aspirin in type 2 diabetic patients with coronary artery disease.
    American heart journal, 2012, Volume: 164, Issue:4

    Topics: Analysis of Variance; Arachidonic Acid; Aspirin; Clopidogrel; Coronary Artery Disease; Cross-Over Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Drug Administration Schedule; Drug Resistance; Female; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Ticlopidine

2012
Impact of renal function on clopidogrel-induced antiplatelet effects in coronary artery disease patients without diabetes mellitus.
    Journal of thrombosis and thrombolysis, 2013, Volume: 36, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Clopidogrel; Coronary Artery Disease; Diabetes Mellitus; Female; Glomerular Filtration Rate; Humans; Kidney; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Ticlopidine

2013
Optimized duration of clopidogrel therapy following treatment with the Endeavor zotarolimus-eluting stent in real-world clinical practice (OPTIMIZE) trial: rationale and design of a large-scale, randomized, multicenter study.
    American heart journal, 2012, Volume: 164, Issue:6

    Topics: Adult; Aspirin; Brazil; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Drug Therapy, Combination; Drug-Eluting Stents; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Postoperative Period; Prospective Studies; Research Design; Sirolimus; Ticlopidine; Time Factors; Treatment Outcome; Young Adult

2012
Benefit of long-term dual anti-platelet therapy in patients treated with drug-eluting stents: from the NHLBI dynamic registry.
    The American journal of cardiology, 2013, Feb-15, Volume: 111, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; Aspirin; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drug-Eluting Stents; Follow-Up Studies; Humans; Immunosuppressive Agents; Paclitaxel; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Recurrence; Registries; Retrospective Studies; Sirolimus; Survival Rate; Ticlopidine; Time Factors; Treatment Outcome; United States

2013
Efficacy and safety of low-dose clopidogrel in Japanese patients after drug-eluting stent implantation: a randomized pilot trial.
    Heart and vessels, 2014, Volume: 29, Issue:1

    Topics: Aged; Asian People; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Japan; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Pilot Projects; Platelet Aggregation Inhibitors; Prospective Studies; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome; Ultrasonography, Interventional

2014
Comparison of antiplatelet efficacy and tolerability of clopidogrel napadisilate with clopidogrel bisulfate in coronary artery disease patients after percutaneous coronary intervention: a prospective, multicenter, randomized, open-label, phase IV, noninfe
    Clinical therapeutics, 2013, Volume: 35, Issue:1

    Topics: Aged; Blood Platelets; Cerebrovascular Disorders; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Point-of-Care Systems; Prospective Studies; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Republic of Korea; Therapeutic Equivalency; Ticlopidine; Time Factors; Treatment Outcome

2013
Genetic variation in PEAR1 is associated with platelet aggregation and cardiovascular outcomes.
    Circulation. Cardiovascular genetics, 2013, Volume: 6, Issue:2

    Topics: Adult; Aged; Alleles; Chromosomes, Human, Pair 1; Clopidogrel; Cohort Studies; Coronary Artery Disease; Female; Genome-Wide Association Study; Genotype; Humans; Male; Middle Aged; Odds Ratio; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Receptors, Cell Surface; Ticlopidine

2013
Oral antiplatelet therapies have no effect on circulating levels of RANTES in patients with coronary artery disease.
    Die Pharmazie, 2002, Volume: 57, Issue:12

    Topics: Aged; Angina, Unstable; Chemokine CCL5; Chemokines; Clopidogrel; Coronary Artery Disease; Female; Heart Failure; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine

2002
A randomized comparison of clopidogrel and aspirin versus ticlopidine and aspirin after the placement of coronary artery stents.
    Journal of the American College of Cardiology, 2003, Mar-19, Volume: 41, Issue:6

    Topics: Aged; Aspirin; Blood Vessel Prosthesis Implantation; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Female; Follow-Up Studies; Graft Occlusion, Vascular; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Complications; Stents; Survival Rate; Ticlopidine; Time Factors

2003
Clopidogrel for coronary stenting: response variability, drug resistance, and the effect of pretreatment platelet reactivity.
    Circulation, 2003, Jun-17, Volume: 107, Issue:23

    Topics: Adenosine Diphosphate; Aged; Aspirin; Biomarkers; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Drug Resistance; Female; Flow Cytometry; Genetic Variation; Humans; Male; P-Selectin; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Stents; Ticlopidine

2003
Lack of adverse clopidogrel-atorvastatin clinical interaction from secondary analysis of a randomized, placebo-controlled clopidogrel trial.
    Circulation, 2003, Aug-26, Volume: 108, Issue:8

    Topics: Angioplasty, Balloon, Coronary; Atorvastatin; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Drug Therapy, Combination; Female; Hemorrhage; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Pyrroles; Randomized Controlled Trials as Topic; Retrospective Studies; Risk Assessment; Stroke; Ticlopidine; Treatment Outcome

2003
Randomized clinical trial of abciximab in diabetic patients undergoing elective percutaneous coronary interventions after treatment with a high loading dose of clopidogrel.
    Circulation, 2004, Dec-14, Volume: 110, Issue:24

    Topics: Abciximab; Aged; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Diabetes Complications; Elective Surgical Procedures; Endpoint Determination; Female; Fibrinolytic Agents; Follow-Up Studies; Humans; Immunoglobulin Fab Fragments; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Risk; Stents; Ticlopidine

2004
What is the risk of stent thrombosis associated with the use of paclitaxel-eluting stents for percutaneous coronary intervention?: a meta-analysis.
    Journal of the American College of Cardiology, 2005, Mar-15, Volume: 45, Issue:6

    Topics: Aged; Angioplasty, Balloon, Coronary; Antineoplastic Agents, Phytogenic; Aspirin; Blood Vessel Prosthesis Implantation; Clopidogrel; Coated Materials, Biocompatible; Coronary Artery Disease; Coronary Thrombosis; Female; Humans; Male; Middle Aged; Paclitaxel; Platelet Aggregation Inhibitors; Postoperative Complications; Risk Factors; Stents; Ticlopidine; Treatment Outcome

2005
Inter-individual variability in response to clopidogrel in patients with coronary artery disease.
    Kardiologia polska, 2005, Volume: 62, Issue:2

    Topics: Adult; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug Resistance; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine; Time Factors; Treatment Outcome

2005
High stability of blood samples for flow cytometric analysis of VASP phosphorylation to measure the clopidogrel responsiveness in patients with coronary artery disease.
    Thrombosis and haemostasis, 2005, Volume: 94, Issue:4

    Topics: Aged; Aged, 80 and over; Cell Adhesion Molecules; Clopidogrel; Coronary Artery Disease; Female; Flow Cytometry; Humans; Male; Microfilament Proteins; Middle Aged; Phosphoproteins; Phosphorylation; Platelet Aggregation Inhibitors; Ticlopidine

2005
Anti-thrombotic action of clopidogrel and P1(A1/A2) polymorphism of beta3 integrin in patients with coronary artery disease not being treated with aspirin.
    Thrombosis and haemostasis, 2005, Volume: 94, Issue:6

    Topics: Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Genotype; Humans; Integrin beta3; Male; P-Selectin; Peptide Fragments; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Polymorphism, Genetic; Prothrombin; Thrombosis; Ticlopidine; Time Factors

2005
Effects of clopidogrel on soluble CD40 ligand and on high-sensitivity C-reactive protein in patients with stable coronary artery disease.
    American heart journal, 2006, Volume: 151, Issue:2

    Topics: Aged; Biomarkers; C-Reactive Protein; CD40 Ligand; Clopidogrel; Coronary Artery Disease; Double-Blind Method; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine

2006
Effect of platelet antigen polymorphism on platelet inhibition by aspirin, clopidogrel, or their combination.
    Journal of the American College of Cardiology, 2006, Feb-07, Volume: 47, Issue:3

    Topics: Adenosine Diphosphate; Antigens, Human Platelet; Aspirin; Blood Platelets; Clopidogrel; Collagen; Coronary Artery Disease; Cytoplasmic Granules; Epinephrine; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Polymorphism, Genetic; Ticlopidine

2006
The influence of body mass index on outcomes and the benefit of antiplatelet therapy following percutaneous coronary intervention.
    The Journal of invasive cardiology, 2006, Volume: 18, Issue:3

    Topics: Aged; Angioplasty, Balloon, Coronary; Body Mass Index; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Regression Analysis; Ticlopidine; Time Factors; Treatment Outcome

2006
Whole blood aggregometry for evaluation of the antiplatelet effects of clopidogrel.
    Thrombosis research, 2007, Volume: 119, Issue:3

    Topics: Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Monitoring, Physiologic; Platelet Aggregation; Platelet Function Tests; Predictive Value of Tests; Ticlopidine; Whole Blood Coagulation Time

2007
Prasugrel achieves greater inhibition of platelet aggregation and a lower rate of non-responders compared with clopidogrel in aspirin-treated patients with stable coronary artery disease.
    European heart journal, 2006, Volume: 27, Issue:10

    Topics: Adult; Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Thiophenes; Ticlopidine

2006
Clopidogrel improves systemic endothelial nitric oxide bioavailability in patients with coronary artery disease: evidence for antioxidant and antiinflammatory effects.
    Arteriosclerosis, thrombosis, and vascular biology, 2006, Volume: 26, Issue:7

    Topics: Acetylcholine; Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aspirin; Biological Availability; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Endothelium, Vascular; Enzyme Inhibitors; Humans; Middle Aged; Nitric Oxide; omega-N-Methylarginine; Ticlopidine; Vasodilation; Vasodilator Agents

2006
Clopidogrel increases expression of chemokines in peripheral blood mononuclear cells in patients with coronary artery disease: results of a double-blind placebo-controlled study.
    Journal of thrombosis and haemostasis : JTH, 2006, Volume: 4, Issue:10

    Topics: Aged; Cells, Cultured; Chemokines; Clopidogrel; Coronary Artery Disease; Double-Blind Method; Endothelium, Vascular; Female; Gene Expression Regulation; Humans; Immunoenzyme Techniques; Leukocytes, Mononuclear; Male; Middle Aged; Placebos; Platelet Aggregation Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Ticlopidine

2006
Diabetes mellitus and platelet function after administration of aspirin and a single 600 mg dose of clopidogrel.
    Journal of thrombosis and haemostasis : JTH, 2006, Volume: 4, Issue:12

    Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Aspirin; Blood Platelets; Clopidogrel; Collagen; Coronary Artery Disease; Diabetes Complications; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Male; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Receptors, Thrombin; Thrombosis; Ticlopidine

2006
Evidence that pre-existent variability in platelet response to ADP accounts for 'clopidogrel resistance'.
    Journal of thrombosis and haemostasis : JTH, 2007, Volume: 5, Issue:1

    Topics: Adenosine Diphosphate; Adult; Aspirin; Bayes Theorem; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug Administration Schedule; Drug Resistance; Female; Humans; Male; Middle Aged; Models, Cardiovascular; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Reference Values; Severity of Illness Index; Ticlopidine; Time Factors

2007
Effects of Erigeron injection on vascular endothelium in patients after intracoronary stenting.
    Chinese journal of integrative medicine, 2006, Volume: 12, Issue:3

    Topics: C-Reactive Protein; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Endothelin-1; Endothelium, Vascular; Erigeron; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Nitric Oxide; Phytotherapy; Plant Preparations; Platelet Aggregation Inhibitors; Stents; Superoxide Dismutase; Ticlopidine

2006
Low response to clopidogrel is associated with cardiovascular outcome after coronary stent implantation.
    European heart journal, 2006, Volume: 27, Issue:20

    Topics: Adult; Aged; Aged, 80 and over; Clopidogrel; Coronary Artery Disease; Disease-Free Survival; Drug Resistance; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Regression Analysis; Stents; Ticlopidine; Treatment Failure

2006
The role of aspirin resistance on outcome in patients with acute coronary syndrome and the effect of clopidogrel therapy in the prevention of major cardiovascular events.
    Journal of thrombosis and thrombolysis, 2006, Volume: 22, Issue:2

    Topics: Angina, Unstable; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Resistance; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Prospective Studies; Ticlopidine; Treatment Outcome

2006
Benefit of a 600-mg loading dose of clopidogrel on platelet reactivity and clinical outcomes in patients with non-ST-segment elevation acute coronary syndrome undergoing coronary stenting.
    Journal of the American College of Cardiology, 2006, Oct-03, Volume: 48, Issue:7

    Topics: Aged; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Electrocardiography; Female; Humans; Male; Middle Aged; Myocardial Infarction; Myocardial Ischemia; P-Selectin; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Recurrence; Stents; Ticlopidine; Treatment Outcome

2006
Impact of P-glycoprotein on clopidogrel absorption.
    Clinical pharmacology and therapeutics, 2006, Volume: 80, Issue:5

    Topics: Administration, Oral; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Caco-2 Cells; Cell Membrane Permeability; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Down-Regulation; Gene Expression; Genotype; Humans; Intestinal Absorption; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; RNA, Messenger; Ticlopidine

2006
A single loading dose of clopidogrel causes dose-dependent improvement of endothelial dysfunction in patients with stable coronary artery disease: results of a double-blind, randomized study.
    Atherosclerosis, 2008, Volume: 196, Issue:2

    Topics: Aged; Blood Platelets; Cell Adhesion Molecules; Clopidogrel; Coronary Artery Disease; Dilatation, Pathologic; Double-Blind Method; Endothelium, Vascular; Female; Humans; Male; Microfilament Proteins; Middle Aged; Phosphoproteins; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2Y12; Superoxides; Ticlopidine

2008
Effect of timing of clopidogrel administration on 30-day clinical outcomes: 300-mg loading dose immediately after coronary stenting versus pretreatment 6 to 24 hours before stenting in a large unselected patient cohort.
    American heart journal, 2007, Volume: 153, Issue:2

    Topics: Clopidogrel; Combined Modality Therapy; Coronary Artery Disease; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Myocardial Revascularization; Platelet Aggregation Inhibitors; Preoperative Care; Prospective Studies; Registries; Stents; Ticlopidine; Time Factors; Treatment Outcome

2007
Randomized comparison of a high clopidogrel maintenance dose in patients with diabetes mellitus and coronary artery disease: results of the Optimizing Antiplatelet Therapy in Diabetes Mellitus (OPTIMUS) study.
    Circulation, 2007, Feb-13, Volume: 115, Issue:6

    Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Clopidogrel; Coronary Artery Disease; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Pilot Projects; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Ticlopidine

2007
Clinical relevance of aspirin resistance in patients with stable coronary artery disease: a prospective follow-up study (PROSPECTAR).
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2007, Volume: 18, Issue:2

    Topics: Aged; Angina Pectoris; Aspirin; Clopidogrel; Coronary Artery Disease; Death; Drug Resistance; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation; Platelet Function Tests; Prevalence; Stroke; Survival Analysis; Ticlopidine; Treatment Outcome

2007
Effects of persistent platelet reactivity despite aspirin therapy on cardiac troponin I and creatine kinase-MB levels after elective percutaneous coronary interventions.
    Journal of thrombosis and thrombolysis, 2008, Volume: 25, Issue:3

    Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Biomarkers; Clopidogrel; Coronary Artery Disease; Creatine Kinase, MB Form; Drug Resistance; Female; Humans; Male; Middle Aged; Myocardium; Necrosis; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Tablets, Enteric-Coated; Thrombosis; Ticlopidine; Time Factors; Troponin I; Up-Regulation

2008
The additive antiplatelet action of clopidogrel in patients with coronary artery disease treated with aspirin.
    Thrombosis and haemostasis, 2007, Volume: 98, Issue:1

    Topics: Adenosine Diphosphate; Adult; Aged; Aspirin; Biomarkers; Case-Control Studies; Clopidogrel; Coronary Artery Disease; Cross-Over Studies; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Flow Cytometry; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine; Treatment Outcome

2007
The paclitaxel-eluting Coroflex Please stent pilot study (PECOPS I) : the one-year clinical follow-up.
    Clinical research in cardiology : official journal of the German Cardiac Society, 2007, Volume: 96, Issue:11

    Topics: Aged; Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Death; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Infarction; Myocardial Revascularization; Paclitaxel; Pilot Projects; Platelet Aggregation Inhibitors; Prospective Studies; Survival Rate; Thrombosis; Ticlopidine; Tubulin Modulators

2007
Efficacy and safety of triple antiplatelet therapy with and without concomitant anticoagulation during elective percutaneous coronary intervention (the REMOVE trial).
    The American journal of cardiology, 2007, Oct-01, Volume: 100, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Eptifibatide; Female; Heparin; Humans; Male; Middle Aged; Peptides; Pilot Projects; Platelet Aggregation Inhibitors; Prospective Studies; Pyridines; Ticlopidine; Treatment Outcome

2007
Comparison of triple versus dual antiplatelet therapy after drug-eluting stent implantation (from the DECLARE-Long trial).
    The American journal of cardiology, 2007, Oct-01, Volume: 100, Issue:7

    Topics: Aged; Aspirin; Cilostazol; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Coronary Vessels; Drug Delivery Systems; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Male; Middle Aged; Paclitaxel; Platelet Aggregation Inhibitors; Sirolimus; Stents; Tetrazoles; Ticlopidine; Time Factors; Treatment Outcome; Tunica Intima

2007
TAXUS VI 2-year follow-up: randomized comparison of polymer-based paclitaxel-eluting with bare metal stents for treatment of long, complex lesions.
    European heart journal, 2007, Volume: 28, Issue:21

    Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Coronary Thrombosis; Drug-Eluting Stents; Epidemiologic Methods; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Myocardial Revascularization; Paclitaxel; Platelet Aggregation Inhibitors; Polymers; Ticlopidine

2007
Clopidogrel desensitization after drug-eluting stent placement.
    Journal of the American College of Cardiology, 2007, Nov-20, Volume: 50, Issue:21

    Topics: Clopidogrel; Coronary Artery Disease; Desensitization, Immunologic; Drug Hypersensitivity; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome

2007
Prasugrel achieves greater and faster P2Y12receptor-mediated platelet inhibition than clopidogrel due to more efficient generation of its active metabolite in aspirin-treated patients with coronary artery disease.
    European heart journal, 2008, Volume: 29, Issue:1

    Topics: Adult; Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Double-Blind Method; Female; Humans; Male; Middle Aged; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Thiophenes; Ticlopidine; Treatment Outcome

2008
Effect of clopidogrel treatment on stress-induced platelet activation and myocardial ischemia in aspirin-treated patients with stable coronary artery disease.
    Thrombosis and haemostasis, 2007, Volume: 98, Issue:6

    Topics: Adenosine Diphosphate; Aged; Aspirin; Blood Platelets; C-Reactive Protein; CD40 Ligand; Clopidogrel; Collagen; Coronary Artery Disease; Double-Blind Method; Drug Therapy, Combination; Electrocardiography, Ambulatory; Exercise Test; Flow Cytometry; Heart Rate; Humans; Interleukin-6; Leukocytes; Male; Middle Aged; Myocardial Ischemia; P-Selectin; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Research Design; Stress, Physiological; Thrombin; Ticlopidine; Treatment Outcome

2007
[Effects of intensive antiplatelet therapy in patients with high platelet aggregability after percutaneous coronary intervention].
    Zhonghua xin xue guan bing za zhi, 2007, Volume: 35, Issue:9

    Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Ticlopidine

2007
Randomized comparison of cilostazol vs clopidogrel after drug-eluting stenting in diabetic patients--clilostazol for diabetic patients in drug-eluting stent (CIDES) trial.
    Circulation journal : official journal of the Japanese Circulation Society, 2008, Volume: 72, Issue:1

    Topics: Aged; Aspirin; Cilostazol; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Coronary Restenosis; Diabetes Complications; Drug Therapy, Combination; Drug-Eluting Stents; Humans; Male; Middle Aged; Tetrazoles; Ticlopidine; Treatment Outcome

2008
Functional impact of high clopidogrel maintenance dosing in patients undergoing elective percutaneous coronary interventions. Results of a randomized study.
    Thrombosis and haemostasis, 2008, Volume: 99, Issue:1

    Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Female; Florida; Humans; Male; Middle Aged; Pilot Projects; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Research Design; Spain; Stents; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome

2008
Prevalence of platelet nonresponsiveness to aspirin in patients treated for secondary stroke prophylaxis and in patients with recurrent ischemic events.
    Journal of clinical pharmacology, 2008, Volume: 48, Issue:3

    Topics: Age Factors; Aged; Anti-Inflammatory Agents; Arachidonic Acid; Aspirin; Blood Platelets; Clopidogrel; Collagen; Coronary Artery Disease; Dipyridamole; Drug Therapy, Combination; Female; Humans; Ischemic Attack, Transient; Male; Odds Ratio; Platelet Aggregation; Recurrence; Stroke; Ticlopidine; Time Factors; Treatment Failure

2008
Clopidogrel 600-mg double loading dose achieves stronger platelet inhibition than conventional regimens: results from the PREPAIR randomized study.
    Journal of the American College of Cardiology, 2008, Mar-18, Volume: 51, Issue:11

    Topics: Aged; Angioplasty, Balloon, Coronary; Blood Platelets; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Coronary Thrombosis; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Injections, Intravenous; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome

2008
Drug-eluting stenting followed by cilostazol treatment reduces late restenosis in patients with diabetes mellitus the DECLARE-DIABETES Trial (A Randomized Comparison of Triple Antiplatelet Therapy with Dual Antiplatelet Therapy After Drug-Eluting Stent Im
    Journal of the American College of Cardiology, 2008, Mar-25, Volume: 51, Issue:12

    Topics: Aged; Aspirin; Cilostazol; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Coronary Restenosis; Coronary Vessels; Diabetes Mellitus; Diabetic Angiopathies; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Hyperplasia; Male; Middle Aged; Platelet Aggregation Inhibitors; Tetrazoles; Ticlopidine; Treatment Outcome; Tunica Intima

2008
A novel bioresorbable polymer paclitaxel-eluting stent for the treatment of single and multivessel coronary disease: primary results of the COSTAR (Cobalt Chromium Stent With Antiproliferative for Restenosis) II study.
    Journal of the American College of Cardiology, 2008, Apr-22, Volume: 51, Issue:16

    Topics: Absorbable Implants; Angioplasty, Balloon, Coronary; Antineoplastic Agents, Phytogenic; Chromium Alloys; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Coronary Restenosis; Diabetes Mellitus; Female; Humans; Male; Middle Aged; Paclitaxel; Platelet Aggregation Inhibitors; Polymers; Risk; Thromboembolism; Ticlopidine; Time Factors

2008
Phase 1b randomized study of antidote-controlled modulation of factor IXa activity in patients with stable coronary artery disease.
    Circulation, 2008, Jun-03, Volume: 117, Issue:22

    Topics: Aged; Antidotes; Aptamers, Nucleotide; Aspirin; Clopidogrel; Coronary Artery Disease; Double-Blind Method; Drug Combinations; Factor IXa; Female; Humans; Male; Middle Aged; Oligonucleotides; Ticlopidine; Treatment Outcome

2008
Acute antithrombotic effect of a front-loaded regimen of clopidogrel in patients with atherosclerosis on aspirin.
    Arteriosclerosis, thrombosis, and vascular biology, 2000, Volume: 20, Issue:10

    Topics: Adenosine Diphosphate; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Double-Blind Method; Drug Therapy, Combination; Fibrinogen; Fibrinolytic Agents; Humans; Perfusion; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine; Time Factors

2000
Clopidogrel therapy in patients undergoing coronary stenting: value of a high-loading-dose regimen.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2002, Volume: 55, Issue:4

    Topics: Abciximab; Aged; Antibodies, Monoclonal; Blood Vessel Prosthesis Implantation; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Immunoglobulin Fab Fragments; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Preoperative Care; Stents; Ticlopidine

2002
Use of clopidogrel loading, enoxaparin, and double-bolus eptifibatide in the setting of early percutaneous coronary intervention for acute coronary syndromes.
    The Journal of invasive cardiology, 2002, Volume: 14, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Enoxaparin; Eptifibatide; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Peptides; Pilot Projects; Platelet Aggregation Inhibitors; Preoperative Care; Ticlopidine; Treatment Outcome

2002

Other Studies

561 other study(ies) available for clopidogrel and Coronary Artery Disease

ArticleYear
Platelet reactivity and clinical outcomes following percutaneous coronary intervention in complex higher-risk patients.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2022, 02-01, Volume: 23, Issue:2

    Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Purinergic P2Y Receptor Antagonists; Risk Assessment; Thrombosis

2022
In-hospital Bleeding Outcomes of Oral Anticoagulant and Dual Antiplatelet Therapy During Percutaneous Coronary Intervention: An Analysis From the Japanese Nationwide Registry.
    Journal of cardiovascular pharmacology, 2021, 04-01, Volume: 78, Issue:2

    Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Dual Anti-Platelet Therapy; Factor Xa Inhibitors; Female; Hemorrhage; Humans; Japan; Male; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Postoperative Complications; Prasugrel Hydrochloride; Registries; Retrospective Studies; Warfarin

2021
Influence of
    Journal of the American Heart Association, 2021, 11-02, Volume: 10, Issue:21

    Topics: Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Humans; MicroRNAs; Platelet Aggregation Inhibitors; Ticlopidine

2021
Association between Paraoxonase-1 p.Q192R Polymorphism and Coronary Artery Disease susceptibility in the Colombian Population.
    Vascular health and risk management, 2021, Volume: 17

    Topics: Aryldialkylphosphatase; Clopidogrel; Colombia; Coronary Artery Disease; Genotype; Humans; Platelet Aggregation Inhibitors

2021
Clinical and Pharmacological Parameters Determine Relapse During Clopidogrel Treatment of Acute Coronary Syndrome.
    Journal of clinical pharmacology, 2022, Volume: 62, Issue:6

    Topics: Acute Coronary Syndrome; Aspirin; Calcium Channel Blockers; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Diabetes Mellitus, Type 2; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Recurrence; Retrospective Studies; Ticlopidine; Treatment Outcome

2022
Clopidogrel Monotherapy More Effective Than Aspirin to Prevent Coronary Events After PCI With Drug-Eluting Stents.
    American family physician, 2022, 02-01, Volume: 105, Issue:2

    Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Drug-Eluting Stents; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Treatment Outcome

2022
Circadian variations of platelet reactivity on clopidogrel in patients treated with elective percutaneous coronary intervention.
    Journal of thrombosis and thrombolysis, 2022, Volume: 54, Issue:1

    Topics: Blood Platelets; Clopidogrel; Coronary Artery Disease; Humans; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine

2022
Dual Antiplatelet Therapy Discontinuation, Platelet Reactivity, and Adverse Outcomes After Successful Percutaneous Coronary Intervention.
    JACC. Cardiovascular interventions, 2022, 04-25, Volume: 15, Issue:8

    Topics: Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prospective Studies; Ticlopidine; Treatment Outcome

2022
Future of antithrombotic therapy for heart failure with coronary artery disease.
    European heart journal. Cardiovascular pharmacotherapy, 2022, 08-11, Volume: 8, Issue:5

    Topics: Clopidogrel; Coronary Artery Disease; Fibrinolytic Agents; Heart Failure; Humans; Ticlopidine

2022
New Insights Into Long- Versus Short-Term Dual Antiplatelet Therapy Duration in Patients After Stenting for Left Main Coronary Artery Disease: Findings From a Prospective Observational Study.
    Circulation. Cardiovascular interventions, 2022, Volume: 15, Issue:6

    Topics: Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Hemorrhage; Humans; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Stents; Treatment Outcome

2022
Comparative Effectiveness and Safety of Ticagrelor Versus Clopidogrel for Elderly Chinese Patients Undergoing Percutaneous Coronary Intervention: A Single-Center Retrospective Cohort Study.
    Drugs & aging, 2022, Volume: 39, Issue:9

    Topics: Acute Coronary Syndrome; Aged; Aspirin; China; Cholesterol; Clopidogrel; Cohort Studies; Coronary Artery Disease; Hemorrhage; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Retrospective Studies; Ticagrelor; Treatment Outcome

2022
Elevated serum C1q is an independent predictor of high residual platelet reactivity in CAD patients receiving clopidogrel therapy.
    Frontiers in immunology, 2022, Volume: 13

    Topics: Adenosine; Adenosine Diphosphate; Clopidogrel; Complement C1q; Coronary Artery Disease; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Thrombosis; Ticagrelor; Ticlopidine

2022
On-Treatment Platelet Reactivity and Ischemic Outcomes in Patients With Diabetes Mellitus: Two-Year Results From ADAPT-DES.
    Journal of the American Heart Association, 2023, 01-03, Volume: 12, Issue:1

    Topics: Blood Platelets; Clopidogrel; Coronary Artery Disease; Diabetes Mellitus; Humans; Ischemia; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prospective Studies; Risk Factors; Treatment Outcome

2023
Within and beyond 12-month efficacy and safety of antithrombotic strategies in patients with established coronary artery disease: two companion network meta-analyses of the 2022 joint clinical consensus statement of the European Association of Percutaneou
    European heart journal. Cardiovascular pharmacotherapy, 2023, 04-10, Volume: 9, Issue:3

    Topics: Aspirin; Cardiology; Clopidogrel; Coronary Artery Disease; Fibrinolytic Agents; Hemorrhage; Humans; Myocardial Infarction; Network Meta-Analysis; Purinergic P2Y Receptor Antagonists; Rivaroxaban; Stroke; Ticagrelor

2023
Decreased platelet miR-199a-5p level might lead to high on-clopidogrel platelet reactivity in patients with coronary artery disease.
    Platelets, 2023, Volume: 34, Issue:1

    Topics: Blood Platelets; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Humans; MicroRNAs; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Ticlopidine

2023
[Debate on dual pathway inhibition: Antiplatelet therapy in patients with peripheral artery disease: old but gold?]
    Giornale italiano di cardiologia (2006), 2023, Volume: 24, Issue:4 Suppl 2

    Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Humans; Peripheral Arterial Disease; Platelet Aggregation Inhibitors

2023
Impact of the Xinsorb Scaffold-Related Parameters on Platelet Reactivity in Patients with Single De Novo Coronary Artery Lesions Undergoing Clopidogrel Treatment.
    Anatolian journal of cardiology, 2023, 07-03, Volume: 27, Issue:7

    Topics: Cholesterol; Clopidogrel; Coronary Artery Disease; Humans; Lipoproteins, HDL; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Treatment Outcome

2023
Prescription patterns of P2Y12 inhibitors following revascularization in the United States: 2013-2018.
    Clinical and translational science, 2023, Volume: 16, Issue:10

    Topics: Acute Coronary Syndrome; Aged; Clopidogrel; Coronary Artery Disease; Humans; Platelet Aggregation Inhibitors; Prescriptions; Purinergic P2Y Receptor Antagonists; Ticagrelor; Treatment Outcome; United States

2023
[Comparison of Various Regimens of Antithrombotic Therapy in Patients With Valvular Heart Disease and Coronary Artery Disease After Surgical and Interventional Interventions].
    Kardiologiia, 2023, Jul-28, Volume: 63, Issue:7

    Topics: Anticoagulants; Aspirin; Clopidogrel; Coronary Artery Disease; Female; Fibrinolytic Agents; Heart Valve Diseases; Hemorrhage; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Thromboembolism; Treatment Outcome

2023
Understanding the Effects of NOAC Combined with Antiplatelet Therapy on Clot Kinetics.
    Thrombosis and haemostasis, 2020, Volume: 120, Issue:1

    Topics: Anticoagulants; Aspirin; Clopidogrel; Coronary Artery Disease; Dimaprit; Humans; Kinetics; Platelet Aggregation Inhibitors; Pyridines; Thiazoles

2020
Pharmacogenomic polygenic response score predicts ischaemic events and cardiovascular mortality in clopidogrel-treated patients.
    European heart journal. Cardiovascular pharmacotherapy, 2020, 07-01, Volume: 6, Issue:4

    Topics: Aged; Brain Ischemia; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Decision Support Techniques; Europe; Female; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Pharmacogenomic Variants; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Predictive Value of Tests; Risk Assessment; Risk Factors; Stents; Stroke; Treatment Outcome

2020
Ticagrelor Compared to Clopidogrel in Acute Coronary Syndrome and Stable Coronary Artery Disease.
    American family physician, 2019, 11-01, Volume: 100, Issue:9

    Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Ticagrelor; Ticlopidine

2019
Incremental role of glycaemic variability over HbA1c in identifying type 2 diabetic patients with high platelet reactivity undergoing percutaneous coronary intervention.
    Cardiovascular diabetology, 2019, 11-09, Volume: 18, Issue:1

    Topics: Aged; Biomarkers; Blood Glucose; Blood Platelets; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Risk Assessment; Risk Factors; Treatment Outcome

2019
Impact of high on-treatment platelet reactivity on outcomes following PCI in patients on hemodialysis: An ADAPT-DES substudy.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2020, 10-01, Volume: 96, Issue:4

    Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug-Eluting Stents; Dual Anti-Platelet Therapy; Female; Germany; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Registries; Renal Dialysis; Renal Insufficiency, Chronic; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome

2020
Interaction Between Diabetes Mellitus and Platelet Reactivity in Determining Long-Term Outcomes Following Percutaneous Coronary Intervention.
    Journal of cardiovascular translational research, 2020, Volume: 13, Issue:4

    Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Diabetes Mellitus; Drug Resistance; Dual Anti-Platelet Therapy; Female; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Risk Assessment; Risk Factors; Stents; Time Factors; Treatment Outcome

2020
Long-Term Efficacy of Extended Dual Antiplatelet Therapy After Left Main Coronary Artery Bifurcation Stenting.
    The American journal of cardiology, 2020, 02-01, Volume: 125, Issue:3

    Topics: Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Coronary Vessels; Drug-Eluting Stents; Dual Anti-Platelet Therapy; Female; Follow-Up Studies; Graft Occlusion, Vascular; Humans; Incidence; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prognosis; Registries; Republic of Korea; Retrospective Studies; Survival Rate; Time Factors

2020
MAPT (Mono Antiplatelet Therapy) as Regular Regimen After COBRA PzF™ NanoCoated Coronary Stent (NCS) Implantation.
    Cardiovascular revascularization medicine : including molecular interventions, 2020, Volume: 21, Issue:6

    Topics: Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Chromium Alloys; Clopidogrel; Coated Materials, Biocompatible; Coronary Artery Disease; Coronary Thrombosis; Female; Hemorrhage; Humans; Male; Organophosphorus Compounds; Platelet Aggregation Inhibitors; Polymers; Prospective Studies; Prosthesis Design; Registries; Risk Assessment; Risk Factors; Stents; Time Factors; Treatment Outcome

2020
Clopidogrel Responsiveness in Patients With Decompensated Cirrhosis of the Liver Undergoing Pre-Transplant PCI.
    JACC. Cardiovascular interventions, 2020, 03-09, Volume: 13, Issue:5

    Topics: Clopidogrel; Coronary Angiography; Coronary Artery Disease; Drug Resistance; Humans; Liver Cirrhosis; Liver Transplantation; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Risk Factors; Time Factors; Treatment Outcome; Waiting Lists

2020
Comparison of the Effect of Age (< 75 Versus ≥ 75) on the Efficacy and Safety of Dual Therapy (Dabigatran + Clopidogrel or Ticagrelor) Versus Triple Therapy (Warfarin + Aspirin + Clopidogrel or Ticagrelor) in Patients With Atrial Fibrillation After Percut
    The American journal of cardiology, 2020, 03-01, Volume: 125, Issue:5

    Topics: Age Factors; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Coronary Artery Disease; Dabigatran; Drug Therapy, Combination; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Revascularization; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Proportional Hazards Models; Stroke; Thromboembolism; Ticagrelor; Treatment Outcome; Warfarin

2020
Impact of Anemia on the Risk of Bleeding Following Percutaneous Coronary Interventions in Patients ≥75 Years of Age.
    The American journal of cardiology, 2020, 04-15, Volume: 125, Issue:8

    Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Anemia; Angina, Unstable; Anticoagulants; Antithrombins; Aspirin; Cause of Death; Clopidogrel; Comorbidity; Coronary Artery Disease; Drug-Eluting Stents; Female; Gastrointestinal Hemorrhage; Hemorrhage; Heparin; Hirudins; Humans; Intracranial Hemorrhages; Kaplan-Meier Estimate; Male; Myocardial Infarction; Peptide Fragments; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Postoperative Care; Postoperative Hemorrhage; Prasugrel Hydrochloride; Proportional Hazards Models; Prospective Studies; Recombinant Proteins; Risk Assessment; Stents; Ticagrelor; Urologic Diseases

2020
Efficacy and safety of different ticagrelor regimens versus clopidogrel in patients with coronary artery disease: a retrospective multicenter study (SUPERIOR).
    Platelets, 2021, Jan-02, Volume: 32, Issue:1

    Topics: Aged; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Ticagrelor

2021
Ticagrelor Versus Clopidogrel in Patients with Two CYP2C19 Loss-of-Function Alleles Undergoing Percutaneous Coronary Intervention.
    Cardiovascular drugs and therapy, 2020, Volume: 34, Issue:2

    Topics: Aged; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Cytochrome P-450 CYP2C19; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Pharmacogenomic Variants; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Registries; Retrospective Studies; Risk Assessment; Risk Factors; Stents; Ticagrelor; Time Factors; Treatment Outcome

2020
Genetic polymorphisms of high platelet reactivity in Chinese patients with coronary heart disease under clopidogrel therapy.
    International journal of clinical pharmacy, 2020, Volume: 42, Issue:1

    Topics: Aged; Asian People; Clopidogrel; Coronary Artery Disease; Female; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide

2020
Ischemic Versus Bleeding Outcomes After Percutaneous Coronary Interventions in Patients With High Bleeding Risk.
    The American journal of cardiology, 2020, 06-01, Volume: 125, Issue:11

    Topics: Aged; Aspirin; Cause of Death; Clopidogrel; Comorbidity; Coronary Artery Disease; Dual Anti-Platelet Therapy; Female; Gastrointestinal Hemorrhage; Heart Failure; Hemorrhage; Humans; Male; Middle Aged; Mortality; Myocardial Infarction; Myocardial Revascularization; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Prevalence; Renal Insufficiency; Risk; Risk Assessment; Stents; Thrombosis

2020
Coronary stent embolism to the right posterior cerebral artery.
    Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir, 2020, Volume: 48, Issue:3

    Topics: Angioplasty, Balloon, Coronary; Aspirin; Atropine; Clopidogrel; Coronary Angiography; Coronary Artery Bypass; Coronary Artery Disease; Coronary Vessels; Drug Therapy, Combination; Embolism; Follow-Up Studies; Heart Arrest; Humans; Male; Middle Aged; Parasympatholytics; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Posterior Cerebral Artery; Prosthesis Failure; Stents; Treatment Outcome

2020
Early dual antiplatelet therapy versus aspirin monotherapy after coronary artery bypass surgery: survival and safety outcomes.
    The Journal of cardiovascular surgery, 2020, Volume: 61, Issue:5

    Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Dual Anti-Platelet Therapy; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome

2020
Genomewide Association Study of Platelet Reactivity and Cardiovascular Response in Patients Treated With Clopidogrel: A Study by the International Clopidogrel Pharmacogenomics Consortium.
    Clinical pharmacology and therapeutics, 2020, Volume: 108, Issue:5

    Topics: Aged; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Female; Genome-Wide Association Study; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Pharmacogenetics; Pharmacogenomic Variants; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Risk Assessment; Risk Factors; Treatment Outcome

2020
Reduction in Osteoarthritis Risk After Treatment With Ticagrelor Compared to Clopidogrel: A Propensity Score-Matching Analysis.
    Arthritis & rheumatology (Hoboken, N.J.), 2020, Volume: 72, Issue:11

    Topics: Aged; Aged, 80 and over; Clopidogrel; Coronary Artery Disease; Female; Humans; Incidence; Male; Middle Aged; Osteoarthritis; Platelet Aggregation Inhibitors; Propensity Score; Purinergic P2Y Receptor Antagonists; Risk; Ticagrelor; Treatment Outcome

2020
Comparison of dual antiplatelet therapies after coronary endarterectomy combined with coronary artery bypass grafting: a cohort study.
    Journal of cardiothoracic surgery, 2020, Jun-29, Volume: 15, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Cohort Studies; Coronary Artery Bypass; Coronary Artery Disease; Dual Anti-Platelet Therapy; Endarterectomy; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Stroke; Ticagrelor; Treatment Outcome

2020
CYP2C19, PON1, and ABCB1 gene polymorphisms in Han and Uygur populations with coronary artery disease in Northwestern Xinjiang, China, From 2014 Through 2019.
    Medicine, 2020, Jul-17, Volume: 99, Issue:29

    Topics: Aged; Aryldialkylphosphatase; ATP Binding Cassette Transporter, Subfamily B; China; Clopidogrel; Comorbidity; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Ethnicity; Female; Gene Frequency; Genotype; Humans; Male; Middle Aged; Phenotype; Polymorphism, Single Nucleotide; Purinergic P2Y Receptor Antagonists

2020
Clinical outcomes of patients treated using very short duration dual antiplatelet therapy after implantation of biodegradable-polymer drug-eluting stents: rationale and design of a prospective multicenter REIWA registry.
    Cardiovascular intervention and therapeutics, 2020, Volume: 35, Issue:4

    Topics: Absorbable Implants; Clopidogrel; Coronary Artery Disease; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Myocardial Ischemia; Observational Studies as Topic; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Polymers; Prasugrel Hydrochloride; Prospective Studies; Registries; Time Factors; Treatment Outcome

2020
Thrombosis of a Percutaneous Transcatheter Mitral Valve Implant and Its Treatment.
    The Canadian journal of cardiology, 2020, Volume: 36, Issue:10

    Topics: Anticoagulants; Bioprosthesis; Cardiac Catheterization; Clopidogrel; Coronary Artery Disease; Echocardiography; Heart Valve Prosthesis; Heart Valve Prosthesis Implantation; Humans; Male; Middle Aged; Mitral Valve; Mitral Valve Insufficiency; Postoperative Complications; Pulmonary Disease, Chronic Obstructive; Pyrazoles; Pyridones; Thrombosis; Treatment Outcome; Withholding Treatment

2020
Distribution of CYP2C19, ABCB1 and PON1 polymorphisms in Chinese Han, Hui, Uygur and Kazak patients with coronary atherosclerotic heart disease.
    International journal of immunogenetics, 2020, Volume: 47, Issue:6

    Topics: Adult; Aged; Alleles; Aryldialkylphosphatase; Asian People; ATP Binding Cassette Transporter, Subfamily B; China; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Ethnicity; Female; Gene Frequency; Genotype; Humans; Male; Middle Aged; Phenotype; Polymorphism, Single Nucleotide

2020
Impact of the CYP2C19*17 Allele on Outcomes in Patients Receiving Genotype-Guided Antiplatelet Therapy After Percutaneous Coronary Intervention.
    Clinical pharmacology and therapeutics, 2021, Volume: 109, Issue:3

    Topics: Aged; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Female; Genotype; Hemorrhage; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Pharmacogenetics; Pharmacogenomic Testing; Pharmacogenomic Variants; Phenotype; Platelet Aggregation Inhibitors; Precision Medicine; Risk Assessment; Risk Factors; Thrombosis; Time Factors; Treatment Outcome; United States

2021
Efficacy and Safety of Ticagrelor and Clopidogrel in Patients with Stable Coronary Artery Disease Undergoing Percutaneous Coronary Intervention.
    Journal of atherosclerosis and thrombosis, 2021, Aug-01, Volume: 28, Issue:8

    Topics: Aged; Clopidogrel; Coronary Artery Disease; Female; Follow-Up Studies; Humans; Male; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prognosis; Ticagrelor; Treatment Outcome

2021
Serum uric acid level negatively correlated with the prevalence of clopidogrel low response in patients undergoing antiplatelet treatment with aspirin and clopidogrel.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2020, 11-27, Volume: 30, Issue:12

    Topics: Aged; Aged, 80 and over; Aspirin; Biomarkers; Clopidogrel; Coronary Artery Disease; Cross-Sectional Studies; Drug Resistance; Dual Anti-Platelet Therapy; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Risk Assessment; Risk Factors; Treatment Outcome; Up-Regulation; Uric Acid

2020
Association of fractalkine with functional severity of heart failure and impact on clopidogrel efficacy in patients with ischemic heart disease.
    Thrombosis research, 2020, Volume: 196

    Topics: Blood Platelets; Chemokine CX3CL1; Clopidogrel; Coronary Artery Disease; Heart Failure; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Stroke Volume; Ticlopidine; Ventricular Function, Left

2020
Ticagrelor in the management of coronary artery disease.
    Future cardiology, 2021, Volume: 17, Issue:4

    Topics: Acute Coronary Syndrome; Clopidogrel; Coronary Artery Disease; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Ticagrelor; Treatment Outcome

2021
Association of FMO3 rs1736557 polymorphism with clopidogrel response in Chinese patients with coronary artery disease.
    European journal of clinical pharmacology, 2021, Volume: 77, Issue:3

    Topics: Aged; Asian People; Aspirin; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Dual Anti-Platelet Therapy; Female; Genotype; Humans; Male; Middle Aged; Oxygenases; Platelet Aggregation Inhibitors; Polymorphism, Genetic

2021
Antithrombotic therapy according to baseline bleeding risk in patients with atrial fibrillation undergoing percutaneous coronary intervention: applying the PRECISE-DAPT score in RE-DUAL PCI.
    European heart journal. Cardiovascular pharmacotherapy, 2022, 05-05, Volume: 8, Issue:3

    Topics: Anticoagulants; Atrial Fibrillation; Clopidogrel; Coronary Artery Disease; Dabigatran; Drug Therapy, Combination; Fibrinolytic Agents; Hemorrhage; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Ticagrelor

2022
Benefits and Risks of Prolonged Duration Dual Antiplatelet Therapy (Clopidogrel and Aspirin) After Percutaneous Coronary Intervention in High-Risk Patients With Diabetes Mellitus.
    The American journal of cardiology, 2021, 03-01, Volume: 142

    Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Diabetes Complications; Diabetes Mellitus; Dual Anti-Platelet Therapy; Duration of Therapy; Female; Hemorrhage; Humans; Male; Middle Aged; Mortality; Multivariate Analysis; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Postoperative Care; Proportional Hazards Models; Registries; Risk Assessment; Stroke

2021
CARDIOVASCULAR EVENT ASSESSMENT IN PATIENTS WITH NONOBSTRUCTIVE CORONARY ARTERY DISEASE UNDERGOING DUAL ANTIPLATELET TREATMENT.
    Georgian medical news, 2020, Issue:309

    Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Humans; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Treatment Outcome

2020
Intermittent concurrent use of clopidogrel and proton pump inhibitors did not increase risk of adverse clinical outcomes in Chinese patients with coronary artery disease.
    BMC cardiovascular disorders, 2021, 02-05, Volume: 21, Issue:1

    Topics: China; Clopidogrel; Coronary Artery Disease; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Retrospective Studies; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome

2021
The expression profile of platelet-derived miRNA in coronary artery disease patients with clopidogrel resistance.
    Pharmacology research & perspectives, 2021, Volume: 9, Issue:2

    Topics: Aged; Aspirin; Biomarkers; Blood Platelets; Case-Control Studies; Clopidogrel; Cohort Studies; Coronary Artery Disease; Drug Resistance; Dual Anti-Platelet Therapy; Female; Gene Expression Profiling; Humans; Male; MicroRNAs; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation

2021
TMAO: a potential mediator of clopidogrel resistance.
    Scientific reports, 2021, 03-22, Volume: 11, Issue:1

    Topics: Animals; Biomarkers; Blood Platelets; Clopidogrel; Coronary Artery Disease; Disease Models, Animal; Drug Resistance; Male; Methylamines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Purinergic P2Y Receptor Antagonists; Rats

2021
Long-term Outcomes of Clopidogrel Monotherapy versus Prolonged Dual Antiplatelet Therapy beyond 12 Months after Percutaneous Coronary Intervention in High-risk Patients.
    Journal of Korean medical science, 2021, Apr-26, Volume: 36, Issue:16

    Topics: Aged; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Republic of Korea; Stroke; Thrombosis; Treatment Outcome

2021
Dual Antiplatelet Therapy with Clopidogrel and Aspirin Versus Aspirin Monotherapy in Patients Undergoing Coronary Artery Bypass Graft Surgery.
    Journal of the American Heart Association, 2021, Volume: 10, Issue:11

    Topics: Aspirin; Beijing; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Dual Anti-Platelet Therapy; Female; Fibrinolytic Agents; Follow-Up Studies; Humans; Incidence; Male; Middle Aged; Purinergic P2Y Receptor Antagonists; Retrospective Studies; Survival Rate; Treatment Outcome

2021
The association of polymorphisms in related circadian rhythm genes and clopidogrel resistance susceptibility.
    Basic & clinical pharmacology & toxicology, 2021, Volume: 129, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Calcium Channels, L-Type; Circadian Rhythm; CLOCK Proteins; Clopidogrel; Cohort Studies; Coronary Artery Disease; Cryptochromes; Drug Resistance; Female; Genotype; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Protein Kinase C

2021
Polymorphisms in the GCK gene increase the risk of clopidogrel resistance in stable coronary artery disease (SCAD) patients.
    Hematology (Amsterdam, Netherlands), 2021, Volume: 26, Issue:1

    Topics: Aged; Clopidogrel; Coronary Artery Disease; Drug Resistance; Glucokinase; Humans; Middle Aged; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide

2021
Differential Impact of Clinical and Genetic Factors on High Platelet Reactivity in Patients with Coronary Artery Disease Treated with Clopidogrel and Prasugrel.
    Journal of atherosclerosis and thrombosis, 2022, Jul-01, Volume: 29, Issue:7

    Topics: Blood Platelets; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Diabetes Mellitus; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Prospective Studies; Renal Insufficiency, Chronic; Ticlopidine

2022
Twelve-month outcome of patients with an established indication for oral anticoagulation undergoing coronary artery stenting and stratified by the baseline risk of bleeding: Insights from the Warfarin and Coronary Stenting (War-Stent) Registry.
    Cardiovascular revascularization medicine : including molecular interventions, 2017, Volume: 18, Issue:6

    Topics: Administration, Oral; Adult; Aged; Anticoagulants; Clopidogrel; Coronary Artery Disease; Female; Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Registries; Stents; Thrombolytic Therapy; Ticlopidine; Treatment Outcome; Warfarin; Young Adult

2017
On-clopidogrel platelet reactivity as predictor for long-term clinical outcome in patients after planned discontinuation of clopidogrel.
    Thrombosis and haemostasis, 2017, 07-26, Volume: 117, Issue:8

    Topics: Aged; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Drug Administration Schedule; Drug Resistance; Female; Germany; Humans; Kaplan-Meier Estimate; Male; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Proportional Hazards Models; Retrospective Studies; Risk Assessment; Risk Factors; Stents; Ticlopidine; Time Factors; Treatment Outcome

2017
Vitamin D Binding Protein rs7041 polymorphism and high-residual platelet reactivity in patients receiving dual antiplatelet therapy with clopidogrel or ticagrelor.
    Vascular pharmacology, 2017, Volume: 93-95

    Topics: Acute Coronary Syndrome; Adenosine; Aged; Aspirin; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Drug Resistance; Drug Therapy, Combination; Female; Gene Frequency; Genotype; Heterozygote; Homozygote; Humans; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Percutaneous Coronary Intervention; Pharmacogenetics; Pharmacogenomic Testing; Pharmacogenomic Variants; Phenotype; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Risk Factors; Ticagrelor; Ticlopidine; Treatment Outcome; Vitamin D Deficiency; Vitamin D-Binding Protein

2017
Total Thrombus-formation Analysis System Predicts Periprocedural Bleeding Events in Patients With Coronary Artery Disease Undergoing Percutaneous Coronary Intervention.
    Journal of the American Heart Association, 2017, Apr-24, Volume: 6, Issue:4

    Topics: Aged; Aged, 80 and over; Aspirin; Blood Coagulation Tests; Clopidogrel; Coronary Artery Disease; Female; Hemorrhage; Humans; Intraoperative Complications; Male; Microchip Analytical Procedures; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Prasugrel Hydrochloride; Risk Assessment; Ticlopidine

2017
Prevalence, Management, and Long-Term (6-Year) Outcomes of Atrial Fibrillation Among Patients Receiving Drug-Eluting Coronary Stents.
    JACC. Cardiovascular interventions, 2017, 06-12, Volume: 10, Issue:11

    Topics: Aged; Anticoagulants; Aspirin; Atrial Fibrillation; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Drug-Eluting Stents; Female; Fibrinolytic Agents; Hemorrhage; Humans; Incidence; Kaplan-Meier Estimate; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Odds Ratio; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prevalence; Proportional Hazards Models; Republic of Korea; Risk Factors; Stroke; Ticlopidine; Time Factors; Treatment Outcome; Warfarin

2017
Platelet distribution width as the prognostic marker in coronary bifurcation treatment.
    European journal of clinical investigation, 2017, Volume: 47, Issue:7

    Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug-Eluting Stents; Female; Humans; Male; Mean Platelet Volume; Middle Aged; Myocardial Revascularization; Non-ST Elevated Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Recurrence; Ticlopidine; Treatment Outcome

2017
Impact of mean platelet aggregation degree on long-term clinical outcomes among patients undergoing a complex percutaneous coronary intervention.
    Coronary artery disease, 2017, Volume: 28, Issue:6

    Topics: Aged; Aspirin; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Multivariate Analysis; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Proportional Hazards Models; Risk Factors; Stents; Ticlopidine; Time Factors; Treatment Outcome

2017
Discussion.
    The Journal of thoracic and cardiovascular surgery, 2018, Volume: 155, Issue:1

    Topics: Clopidogrel; Coronary Artery Disease; Follow-Up Studies; Humans

2018
Quantifying Ischemic Risk After Percutaneous Coronary Intervention Attributable to High Platelet Reactivity on Clopidogrel (From the Assessment of Dual Antiplatelet Therapy with Drug-Eluting Stents Study).
    The American journal of cardiology, 2017, Sep-15, Volume: 120, Issue:6

    Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drug-Eluting Stents; Female; Germany; Graft Occlusion, Vascular; Humans; Incidence; Israel; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Activation; Platelet Aggregation Inhibitors; Prognosis; Prospective Studies; Quebec; Registries; Risk Assessment; Risk Factors; Survival Rate; Ticlopidine; United States

2017
Platelet reactivity unit (PRU) in patients undergoing elective PCI: Rethinking the optimal cut point.
    Anatolian journal of cardiology, 2017, Volume: 18, Issue:2

    Topics: Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Drug-Eluting Stents; Humans; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors

2017
Causes, Timing, and Impact of Dual Antiplatelet Therapy Interruption for Surgery (from the Patterns of Non-adherence to Anti-platelet Regimens In Stented Patients Registry).
    The American journal of cardiology, 2017, Sep-15, Volume: 120, Issue:6

    Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Medication Adherence; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Preoperative Care; Prospective Studies; Registries; Retrospective Studies; Ticlopidine; Time Factors; Withholding Treatment

2017
The effect of CYP2C19 genetic polymorphism and non-genetic factors on clopidogrel platelets inhibition in East Asian coronary artery disease patients.
    Thrombosis research, 2017, Volume: 158

    Topics: Asian People; Blood Platelets; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Female; Humans; Male; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Ticlopidine

2017
    Journal of pharmaceutical and biomedical analysis, 2017, Nov-30, Volume: 146

    Topics: Biomarkers; Blood Platelets; Clopidogrel; Coronary Artery Disease; Cross-Sectional Studies; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Proton Magnetic Resonance Spectroscopy; Ticlopidine

2017
Antiplatelet therapy after coronary bypass surgery: "Broken portions" and "uncertainty" in the search for "absolute truth".
    The Journal of thoracic and cardiovascular surgery, 2018, Volume: 155, Issue:1

    Topics: Clopidogrel; Coronary Artery Disease; Follow-Up Studies; Humans; Platelet Aggregation Inhibitors; Uncertainty

2018
Impact of Long-Term Dual Antiplatelet Therapy on Immature Platelet Count and Platelet Reactivity.
    Angiology, 2018, Volume: 69, Issue:6

    Topics: Acute Coronary Syndrome; Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Count; Ticagrelor

2018
Clopidogrel or ticagrelor in acute coronary syndrome patients treated with newer-generation drug-eluting stents: CHANGE DAPT.
    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2017, Nov-20, Volume: 13, Issue:10

    Topics: Acute Coronary Syndrome; Adenosine; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Drug-Eluting Stents; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Ticagrelor; Ticlopidine

2017
Pharmacometabolomics analysis of plasma to phenotype clopidogrel high on treatment platelets reactivity in coronary artery disease patients.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2018, May-30, Volume: 117

    Topics: Aged; Biomarkers; Blood Platelets; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Drug Monitoring; Drug Resistance; Female; Genotype; Humans; Male; Metabolomics; Middle Aged; Percutaneous Coronary Intervention; Pharmacogenomic Variants; Phenotype; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Proton Magnetic Resonance Spectroscopy; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome

2018
CYP2C19 Genotype is an Independent Predictor of Adverse Cardiovascular Outcome in Iraqi Patients on Clopidogrel After Percutaneous Coronary Intervention.
    Journal of cardiovascular pharmacology, 2018, Volume: 71, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Clinical Decision-Making; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Drug Resistance; Female; Gene Frequency; Genotype; Humans; Iraq; Male; Middle Aged; Patient Selection; Percutaneous Coronary Intervention; Pharmacogenetics; Pharmacogenomic Variants; Phenotype; Platelet Aggregation Inhibitors; Precision Medicine; Risk Factors; Treatment Outcome

2018
Novel assay demonstrates that coronary artery disease patients have heightened procoagulant platelet response.
    Journal of thrombosis and haemostasis : JTH, 2018, Volume: 16, Issue:6

    Topics: Aged; Arsenicals; Aspirin; Biomarkers; Blood Coagulation; Blood Platelets; Case-Control Studies; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Drug Resistance; Female; Flow Cytometry; Glutathione; Humans; Male; Middle Aged; P-Selectin; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests

2018
Platelet Inhibition and Bleeding in Patients Undergoing Non-Cardiac Surgery-The BIANCA Observational Study.
    Thrombosis and haemostasis, 2018, Volume: 118, Issue:5

    Topics: Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Blood Platelets; Cell Adhesion Molecules; Clopidogrel; Coronary Artery Disease; Drug Administration Schedule; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Male; Microfilament Proteins; Middle Aged; Percutaneous Coronary Intervention; Phosphoproteins; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Postoperative Hemorrhage; Preoperative Care; Prospective Studies; Risk Factors; Stents; Time Factors; Time-to-Treatment; Treatment Outcome

2018
Do practice gaps exist in evidence-based medication prescription at hospital discharge in patients undergoing coronary artery bypass surgery & coronary angioplasty?
    The Indian journal of medical research, 2017, Volume: 146, Issue:6

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Angioplasty; Angioplasty, Balloon, Coronary; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Coronary Vessels; Drug Prescriptions; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; India; Male; Middle Aged; Percutaneous Coronary Intervention; Professional Practice Gaps; Retrospective Studies; Ticlopidine

2017
Impact of Clopidogrel on Mortality in Patients With Acute Heart Failure Stratified by Coronary Artery Disease: Findings From the Arabian Gulf Acute Heart Failure Registry (Gulf CARE).
    Angiology, 2018, Volume: 69, Issue:10

    Topics: Acute Disease; Aged; Clopidogrel; Coronary Artery Disease; Female; Heart Failure; Hospital Mortality; Humans; Male; Middle Aged; Prospective Studies; Registries; Risk Assessment; Risk Factors

2018
Leukocyte miR-223-3p is not associated with 
altered platelet responses to clopidogrel in patients with coronary artery disease.
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2018, Apr-28, Volume: 43, Issue:4

    Topics: Adenosine Diphosphate; Blood Platelets; Clopidogrel; Coronary Artery Disease; Humans; Leukocytes; MicroRNAs; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine

2018
Relationship between high platelet reactivity on clopidogrel and long-term clinical outcomes after drug-eluting stents implantation (PAINT-DES): a prospective, propensity score-matched cohort study.
    BMC cardiovascular disorders, 2018, 05-24, Volume: 18, Issue:1

    Topics: Aged; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug-Eluting Stents; Female; Hemorrhage; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Propensity Score; Prospective Studies; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome

2018
Plasma miR-142 predicts major adverse cardiovascular events as an intermediate biomarker of dual antiplatelet therapy.
    Acta pharmacologica Sinica, 2019, Volume: 40, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Biomarkers; Clopidogrel; Coronary Artery Disease; Female; Heart Diseases; Hemorrhage; Humans; Male; MicroRNAs; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prognosis; Prospective Studies; Vascular Diseases

2019
Effect of Physical Exercise on Platelet Reactivity in Patients with Dual Antiplatelet Therapy.
    International journal of sports medicine, 2018, Volume: 39, Issue:8

    Topics: Adenosine Diphosphate; Aspirin; Chromogranin A; Clopidogrel; Coronary Artery Disease; Electrocardiography; Exercise; Exercise Tolerance; Humans; P-Selectin; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Count; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Stents; Thrombosis; Ticlopidine

2018
Platelet Reactivity and Risk of Ischemic Stroke After Coronary Drug-Eluting Stent Implantation: From the ADAPT-DES Study.
    JACC. Cardiovascular interventions, 2018, 07-09, Volume: 11, Issue:13

    Topics: Aged; Aspirin; Biomarkers; Blood Platelets; Brain Ischemia; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Drug-Eluting Stents; Female; Germany; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Registries; Risk Assessment; Risk Factors; Stroke; Time Factors; Treatment Outcome; United States

2018
Predictors of coronary stent thrombosis: a case-control study.
    Journal of thrombosis and thrombolysis, 2018, Volume: 46, Issue:3

    Topics: Aged; Aspirin; Brazil; Case-Control Studies; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Prognosis; Prosthesis Design; Risk Factors; Stents

2018
Association between high on-treatment platelet reactivity to clopidogrel and hepatosteatosis in patients undergoing elective stent implantation.
    Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir, 2018, Volume: 46, Issue:5

    Topics: Case-Control Studies; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Fatty Liver; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Postoperative Complications; Preoperative Period; Prospective Studies; Stents; Ticlopidine; Treatment Outcome

2018
High residual platelet reactivity after switching from clopidogrel to low-dose prasugrel in Japanese patients with end-stage renal disease on hemodialysis.
    Journal of cardiology, 2019, Volume: 73, Issue:1

    Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug Substitution; Female; Humans; Japan; Kidney Failure, Chronic; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Prospective Studies; Renal Dialysis

2019
Extended Clopidogrel Therapy Beyond 12 Months and Long-Term Outcomes in Patients With Diabetes Mellitus Receiving Coronary Arterial Second-Generation Drug-Eluting Stents.
    The American journal of cardiology, 2018, 09-01, Volume: 122, Issue:5

    Topics: Aged; Clopidogrel; Coronary Artery Disease; Diabetes Complications; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Prospective Studies; Registries; Treatment Outcome

2018
Clopidogrel utilization in patients with coronary artery disease and diabetes mellitus: should we determine CYP2C19*2 genotype?
    European journal of clinical pharmacology, 2018, Volume: 74, Issue:12

    Topics: Adult; Aged; Blood Platelets; Clopidogrel; Coronary Artery Disease; Cross-Sectional Studies; Cytochrome P-450 CYP2C19; Diabetes Mellitus; Diabetic Angiopathies; Female; Genotype; Heterozygote; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Function Tests; Polymorphism, Genetic; Young Adult

2018
CRISPLD1 rs12115090 polymorphisms alters antiplatelet potency of clopidogrel in coronary artery disease patients in Chinese Han.
    Gene, 2018, Dec-15, Volume: 678

    Topics: Aged; Asian People; Cell Adhesion Molecules; China; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Ticlopidine; Treatment Outcome

2018
Impact of high on-aspirin platelet reactivity on outcomes following successful percutaneous coronary intervention with drug-eluting stents.
    American heart journal, 2018, Volume: 205

    Topics: Aged; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Injections, Intravenous; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Activation; Platelet Aggregation Inhibitors; Prospective Studies; Registries; Time Factors; Treatment Outcome

2018
Combining Oral Anticoagulants With Platelet Inhibitors in Patients With Atrial Fibrillation and Coronary Disease.
    Journal of the American College of Cardiology, 2018, 10-09, Volume: 72, Issue:15

    Topics: Aged; Anticoagulants; Antithrombins; Aspirin; Atrial Fibrillation; Clopidogrel; Comorbidity; Coronary Artery Disease; Denmark; Drug Therapy, Combination; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Outcome and Process Assessment, Health Care; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Registries; Risk Assessment; Stroke; Warfarin

2018
Response to clopidogrel and of the cytochrome CYP2C19 gene polymorphism.
    La Tunisie medicale, 2018, Volume: 96, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Drug-Related Side Effects and Adverse Reactions; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Genotyping Techniques; Hemorrhage; Heterozygote; Humans; Longitudinal Studies; Male; Middle Aged; Pharmacogenomic Testing; Polymorphism, Genetic; Tunisia

2018
Standard- and Low-Dose Ticagrelor After Percutaneous Coronary Intervention: Finding the Balance for Patients With Stable Coronary Artery Disease.
    Circulation, 2018, 09-25, Volume: 138, Issue:13

    Topics: Clopidogrel; Coronary Artery Disease; Humans; Percutaneous Coronary Intervention; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Steel; Ticagrelor

2018
Prediction of Ischemic and Bleeding Events Using the Dual Antiplatelet Therapy Score in an Unrestricted Percutaneous Coronary Intervention Population.
    Circulation. Cardiovascular interventions, 2018, Volume: 11, Issue:10

    Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Decision Support Techniques; Drug Therapy, Combination; Drug-Eluting Stents; Female; Germany; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Prospective Studies; Registries; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome; United States

2018
The association of clopidogrel and 2-oxo-clopidogrel plasma levels and the 40 months clinical outcome after primary PCI.
    International journal of clinical pharmacy, 2018, Volume: 40, Issue:6

    Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Chest Pain; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prognosis; ST Elevation Myocardial Infarction; Ticlopidine; Treatment Outcome

2018
Efficacy and Safety of Loading Doses With P2Y12-Receptor Antagonists in Patients Without Dual Antiplatelet Therapy Undergoing Elective Coronary Intervention.
    Journal of cardiovascular pharmacology, 2019, Volume: 73, Issue:1

    Topics: Aged; Aged, 80 and over; Clopidogrel; Coronary Artery Disease; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Retrospective Studies; Risk Factors; Ticagrelor; Time Factors; Treatment Outcome

2019
Effect of P2Y
    Thrombosis research, 2019, Volume: 173

    Topics: Adenosine Monophosphate; Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Female; Fibrin Clot Lysis Time; Fibrinolysis; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Thrombosis; Ticagrelor

2019
Variable gender-dependent platelet responses to combined antiplatelet therapy in patients with stable coronary-artery disease.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2018, Volume: 69, Issue:4

    Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Sex Characteristics

2018
EBUS-TBNA on Patients Receiving Antiplatelet Therapy: Are We Throwing Caution to the Wind?
    Journal of bronchology & interventional pulmonology, 2019, Volume: 26, Issue:1

    Topics: Aged; Biopsy, Fine-Needle; Bronchoscopy; Clopidogrel; Coronary Artery Disease; Drug-Eluting Stents; Hemorrhage; Humans; Image-Guided Biopsy; Incidence; Lung Neoplasms; Lymph Nodes; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Prospective Studies; Withholding Treatment

2019
Intravenous Antiplatelet Therapy Bridging in Patients Undergoing Cardiac or Non-Cardiac Surgery Following Percutaneous Coronary Intervention.
    Cardiovascular revascularization medicine : including molecular interventions, 2019, Volume: 20, Issue:9

    Topics: Adenosine Monophosphate; Administration, Intravenous; Aged; Aspirin; Cardiac Surgical Procedures; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug Administration Schedule; Drug Substitution; Drug Therapy, Combination; Drug-Eluting Stents; Eptifibatide; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Perioperative Care; Platelet Aggregation Inhibitors; Retrospective Studies; Risk Factors; Time Factors; Tirofiban; Treatment Outcome

2019
intravenous cangrelor (Kengrexal°) and coronary angioplasty: No advantage over first-line clopidogrel.
    Prescrire international, 2016, Volume: 25, Issue:175

    Topics: Adenosine Monophosphate; Administration, Intravenous; Clopidogrel; Coronary Artery Disease; Hemorrhage; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk Assessment; Treatment Outcome

2016
Cost-effectiveness analysis of pharmacogenomics-guided clopidogrel treatment in Spanish patients undergoing percutaneous coronary intervention.
    The pharmacogenomics journal, 2019, Volume: 19, Issue:5

    Topics: Aged; Clopidogrel; Coronary Artery Disease; Cost-Benefit Analysis; Cytochrome P-450 CYP2C19; Female; Health Care Costs; Humans; Male; Middle Aged; Outcome Assessment, Health Care; Percutaneous Coronary Intervention; Pharmacogenetics; Platelet Aggregation Inhibitors; Quality-Adjusted Life Years; Retrospective Studies

2019
Platelet to red cell distribution width ratio for predicting clopidogrel efficacy in patients undergoing percutaneous coronary interventions: insights from the ONSIDE-TEST study.
    Polish archives of internal medicine, 2019, 02-28, Volume: 129, Issue:2

    Topics: Aged; Clopidogrel; Coronary Artery Disease; Erythrocyte Indices; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Random Allocation; ROC Curve; Treatment Outcome

2019
Association of the coronary artery disease risk gene GUCY1A3 with ischaemic events after coronary intervention.
    Cardiovascular research, 2019, 08-01, Volume: 115, Issue:10

    Topics: Aged; Aged, 80 and over; Aspirin; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Coronary Thrombosis; Drug Resistance; Europe; Female; Genetic Association Studies; Genetic Predisposition to Disease; Hemorrhage; Homozygote; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Registries; Retrospective Studies; Risk Assessment; Risk Factors; Soluble Guanylyl Cyclase; Stents; Time Factors; Treatment Outcome

2019
[Differential expression of lncRNA in patients with coronary artery disease plus clopidogrel resistance].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2019, Jan-28, Volume: 44, Issue:1

    Topics: Clopidogrel; Coronary Artery Disease; Humans; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; RNA, Long Noncoding

2019
Letter by Long et al Regarding Article, "Study of Two Dose Regimens of Ticagrelor Compared With Clopidogrel in Patients Undergoing Percutaneous Coronary Intervention for Stable Coronary Artery Disease".
    Circulation, 2019, 03-12, Volume: 139, Issue:11

    Topics: Clopidogrel; Coronary Artery Disease; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Steel; Ticagrelor

2019
Pharmacodynamic changes of platelet reactivity status in patients with chronic kidney disease after coronary artery stenting.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 113

    Topics: Aged; Blood Platelets; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Female; Flow Cytometry; Genotype; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Renal Insufficiency, Chronic; Stents; Time Factors

2019
Association of PON1 gene promoter DNA methylation with the risk of Clopidogrel resistance in patients with coronary artery disease.
    Journal of clinical laboratory analysis, 2019, Volume: 33, Issue:5

    Topics: Aged; Aryldialkylphosphatase; Asian People; Clopidogrel; Coronary Artery Disease; CpG Islands; DNA Methylation; Drug Resistance; Dyslipidemias; Gene Expression Regulation; Humans; Middle Aged; Platelet Aggregation Inhibitors; Promoter Regions, Genetic; Regression Analysis

2019
Management of aspirin intolerance in patients undergoing percutaneous coronary intervention. The role of mono-antiplatelet therapy: a retrospective, multicenter, study.
    Minerva cardioangiologica, 2019, Volume: 67, Issue:2

    Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Retrospective Studies; Stents; Treatment Outcome

2019
Clinical outcomes and predictive model of platelet reactivity to clopidogrel after acute ischemic vascular events.
    Chinese medical journal, 2019, May-05, Volume: 132, Issue:9

    Topics: Aged; Blood Platelets; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Female; Genotype; Glycated Hemoglobin; Humans; Kaplan-Meier Estimate; Logistic Models; Male; Middle Aged; Multivariate Analysis; Myocardial Ischemia; Regression Analysis

2019
Effect of Selective Serotonin Reuptake Inhibitors on Cardiovascular Outcomes After Percutaneous Coronary Intervention: A Retrospective Cohort Study.
    Clinical drug investigation, 2019, Volume: 39, Issue:6

    Topics: Aged; Clopidogrel; Cohort Studies; Coronary Artery Disease; Female; Hemorrhage; Humans; Male; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Stroke; Treatment Outcome

2019
Multicenter research of bleeding risk between prasugrel and clopidogrel in Japanese patients with coronary artery disease undergoing percutaneous coronary intervention.
    Heart and vessels, 2019, Volume: 34, Issue:10

    Topics: Aged; Aged, 80 and over; Clopidogrel; Coronary Artery Disease; Female; Hemorrhage; Humans; Japan; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Proportional Hazards Models; Retrospective Studies; Risk Factors; Stroke; Survival Rate; Time Factors; Treatment Outcome

2019
Dual platelet antiaggregation therapy after myocardial revascularization surgery.
    Revista da Associacao Medica Brasileira (1992), 2019, Volume: 65, Issue:3

    Topics: Aspirin; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Graft Occlusion, Vascular; Humans; Platelet Aggregation Inhibitors; Ticagrelor; Treatment Outcome; Vascular Patency

2019
Impact of Platelet Endothelial Aggregation Receptor-1 Genotypes on Platelet Reactivity and Early Cardiovascular Outcomes in Patients Undergoing Percutaneous Coronary Intervention and Treated With Aspirin and Clopidogrel.
    Circulation. Cardiovascular interventions, 2019, Volume: 12, Issue:5

    Topics: Acute Coronary Syndrome; Aged; Aspirin; China; Clopidogrel; Coronary Artery Disease; Drug Resistance; Female; Homozygote; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Pharmacogenomic Variants; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Receptors, Cell Surface; Risk Assessment; Risk Factors; Stents; Time Factors; Treatment Outcome

2019
The Impact of Preoperative Clopidogrel on Outcomes After Coronary Artery Bypass Grafting.
    The Annals of thoracic surgery, 2019, Volume: 108, Issue:4

    Topics: Aged; Blood Transfusion; Clopidogrel; Cohort Studies; Coronary Artery Bypass; Coronary Artery Disease; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Patient Readmission; Platelet Aggregation Inhibitors; Postoperative Complications; Reoperation; Survival Rate; Treatment Outcome

2019
Association between High Platelet Reactivity Following Dual Antiplatelet Therapy and Ischemic Events in Japanese Patients with Coronary Artery Disease Undergoing Stent Implantation.
    Journal of atherosclerosis and thrombosis, 2020, Jan-01, Volume: 27, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Female; Humans; Japan; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Platelet Function Tests; Stents; Stroke

2020
Genotyping and phenotyping CYP3A4\\CYP3A5: no association with antiplatelet effect of clopidogrel.
    Molecular biology reports, 2019, Volume: 46, Issue:4

    Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Alleles; Biomarkers, Pharmacological; Blood Platelets; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP3A; Female; Gene Frequency; Genotype; Humans; Male; Middle Aged; Phenotype; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic

2019
Omalizumab for the Treatment of Persistent Drug Induced Urticaria Elicited by Thienopyridines: A Case Report.
    Anti-inflammatory & anti-allergy agents in medicinal chemistry, 2020, Volume: 19, Issue:3

    Topics: Aged; Anti-Allergic Agents; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Drug Hypersensitivity; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Omalizumab; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Treatment Outcome; Urticaria

2020
Replacement of ticagrelor with clopidogrel complicated with acute in‑stent thrombosis.
    Kardiologia polska, 2019, May-24, Volume: 77, Issue:5

    Topics: Clopidogrel; Coronary Artery Disease; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; ST Elevation Myocardial Infarction; Stents; Thrombosis; Ticagrelor

2019
Course of platelet miRNAs after cessation of P2Y12 antagonists.
    European journal of clinical investigation, 2019, Volume: 49, Issue:8

    Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; MicroRNAs; Middle Aged; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Ticagrelor

2019
CYP2C19 pharmacogenetics in patients undergoing coronary stent placement: Is it time to test everyone?
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2019, 06-01, Volume: 93, Issue:7

    Topics: Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Humans; Percutaneous Coronary Intervention; Pharmacogenetics; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Standard of Care; Stents; Treatment Outcome

2019
Impact of platelet turnover on long-term adverse cardiovascular outcomes in patients undergoing percutaneous coronary intervention.
    European journal of clinical investigation, 2019, Volume: 49, Issue:9

    Topics: Acute Coronary Syndrome; Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Mean Platelet Volume; Middle Aged; Multivariate Analysis; Myocardial Infarction; Non-ST Elevated Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Platelet Count; Platelet Function Tests; Prognosis; Proportional Hazards Models; ST Elevation Myocardial Infarction; Stroke

2019
Relationship between drug application and mortality rate in Chinese older coronary artery disease/chronic heart failure patients with and without low glomerular filtration rate.
    BMC pharmacology & toxicology, 2019, 07-26, Volume: 20, Issue:1

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Asian People; Aspirin; Calcium Channel Blockers; Clopidogrel; Coronary Artery Disease; Digoxin; Drug Utilization; Female; Glomerular Filtration Rate; Heart Failure; Hospitalization; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Nitrates

2019
Evaluation of platelet reactivity during combined antiplatelet therapy in patients with stable coronary artery disease in relation to diabetes type 2 and the GPIIB/IIIA receptor gene polymorphism.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2019, Volume: 70, Issue:2

    Topics: Blood Platelets; Clopidogrel; Coronary Artery Disease; Diabetes Mellitus, Type 2; Female; Fibrinogen; Humans; Integrin beta3; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Polymorphism, Genetic; Prospective Studies; Thromboxane B2

2019
Association Between Residual Platelet Reactivity on Clopidogrel Treatment and Severity of Coronary Atherosclerosis: Intrinsic Hypercoagulability as a Mediator.
    Advances in therapy, 2019, Volume: 36, Issue:9

    Topics: Aged; Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Retrospective Studies; Thrombelastography; Thrombophilia; Ticlopidine

2019
The association of P2Y
    Platelets, 2020, May-18, Volume: 31, Issue:4

    Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Extracellular Vesicles; Female; Humans; Male; MicroRNAs; Middle Aged; Phosphatidylserines; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Ticagrelor

2020
The impact of CYP2C19 genotype on cardiovascular events and platelet reactivity in patients with coronary artery disease receiving clopidogrel.
    International journal of cardiology, 2013, Sep-30, Volume: 168, Issue:2

    Topics: Aged; Aryl Hydrocarbon Hydroxylases; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Female; Genotype; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine

2013
Paraoxonase 1 gene polymorphism does not affect clopidogrel response variability but is associated with clinical outcome after PCI.
    PloS one, 2013, Volume: 8, Issue:2

    Topics: Aged; Aged, 80 and over; Aryldialkylphosphatase; Clopidogrel; Coronary Artery Disease; Female; Genotype; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Pharmacogenetics; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Prospective Studies; Risk Factors; Stents; Ticlopidine

2013
Duration of dual antiplatelet therapy after implantation of the first-generation and second-generation drug-eluting stents.
    Coronary artery disease, 2013, Volume: 24, Issue:3

    Topics: Aged; Aspirin; Cardiovascular Agents; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Disease-Free Survival; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Proportional Hazards Models; Prosthesis Design; Retrospective Studies; Risk Assessment; Risk Factors; Sirolimus; Stroke; Ticlopidine; Time Factors; Treatment Outcome

2013
Pharmacological interactions: the next frontier?
    JACC. Cardiovascular interventions, 2013, Volume: 6, Issue:2

    Topics: Atorvastatin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Pyrroles; Ticlopidine

2013
Invited commentary.
    The Annals of thoracic surgery, 2013, Volume: 95, Issue:3

    Topics: Aspirin; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Humans; Male; Ticlopidine; Tranexamic Acid

2013
Hypertension as a risk factor for aspirin and clopidogrel resistance in patients with stable coronary artery disease.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2014, Volume: 20, Issue:7

    Topics: Adult; Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Resistance; Female; Humans; Hypertension; Male; Mean Platelet Volume; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Platelet Count; Risk Factors; Stents; Ticlopidine

2014
Soluble P-selectin level correlates with acetylsalicylic acid but not with clopidogrel response in patients with stable coronary artery disease after a percutaneous coronary intervention.
    Coronary artery disease, 2013, Volume: 24, Issue:4

    Topics: Aged; Anti-Inflammatory Agents; Aryl Hydrocarbon Hydroxylases; Aspirin; CD40 Ligand; Cell Adhesion Molecules; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Drug Resistance; Drug Therapy, Combination; Female; Humans; Male; Microfilament Proteins; Middle Aged; P-Selectin; Percutaneous Coronary Intervention; Phosphoproteins; Platelet Aggregation Inhibitors; Stents; Ticlopidine

2013
Influence of genetic polymorphisms on platelet function, response to antiplatelet drugs and clinical outcomes in patients with coronary artery disease.
    Expert review of cardiovascular therapy, 2013, Volume: 11, Issue:4

    Topics: Adenosine; Aryl Hydrocarbon Hydroxylases; Aryldialkylphosphatase; Aspirin; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood Platelets; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Humans; Pharmacogenetics; Piperazines; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Thiophenes; Ticagrelor; Ticlopidine

2013
Association of PON1 genotype and haplotype with susceptibility to coronary artery disease and clinical outcomes in dual antiplatelet-treated Han Chinese patients.
    European journal of clinical pharmacology, 2013, Volume: 69, Issue:8

    Topics: Aged; Aryldialkylphosphatase; Asian People; Aspirin; Clopidogrel; Coronary Artery Disease; Female; Genetic Predisposition to Disease; Genotype; Haplotypes; Humans; Logistic Models; Male; Middle Aged; Platelet Aggregation Inhibitors; Promoter Regions, Genetic; Ticlopidine; Treatment Outcome

2013
Cytochrome P450 2B6 and 2C9 genotype polymorphism--a possible cause of prasugrel low responsiveness.
    Thrombosis and haemostasis, 2013, Volume: 110, Issue:1

    Topics: Aryl Hydrocarbon Hydroxylases; Aspirin; Biomarkers, Pharmacological; Blood Platelets; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2C9; Drug Resistance; Drug Therapy, Combination; Female; Gene Frequency; Genetic Association Studies; Genotype; Humans; Male; Middle Aged; Piperazines; Polymorphism, Genetic; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Thiophenes; Ticlopidine

2013
Aspirin desensitisation for Chinese patients with coronary artery disease.
    Hong Kong medical journal = Xianggang yi xue za zhi, 2013, Volume: 19, Issue:3

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Desensitization, Immunologic; Drug Hypersensitivity; Drug-Eluting Stents; Female; Hong Kong; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Stents; Ticlopidine; Time Factors

2013
Perioperative management of a neurosurgical patient with a meningioma and recent coronary artery stent.
    Journal of clinical anesthesia, 2013, Volume: 25, Issue:3

    Topics: Aged; Aspirin; Blood Loss, Surgical; Clopidogrel; Contraindications; Coronary Artery Disease; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Meningioma; Perioperative Care; Platelet Aggregation Inhibitors; Thrombosis; Ticlopidine

2013
The impact of the environment on diseases and drugs.
    Journal of the American College of Cardiology, 2013, Aug-06, Volume: 62, Issue:6

    Topics: Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Smoking; Thiophenes; Ticlopidine

2013
Relation between the vasodilator-stimulated phosphoprotein phosphorylation assay and light transmittance aggregometry in East Asian patients after high-dose clopidogrel loading.
    American heart journal, 2013, Volume: 166, Issue:1

    Topics: Blood Platelets; Cell Adhesion Molecules; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Male; Microfilament Proteins; Middle Aged; Phosphoproteins; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Ticlopidine

2013
Impact of the proton pump inhibitors and CYP2C19*2 polymorphism on platelet response to clopidogrel as assessed by four platelet function assays.
    Thrombosis research, 2013, Volume: 132, Issue:2

    Topics: Aged; Alleles; Aryl Hydrocarbon Hydroxylases; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Drug Resistance; Female; Humans; Male; Middle Aged; Platelet Function Tests; Polymorphism, Genetic; Proton Pump Inhibitors; Ticlopidine

2013
Pharmacogenomics of anti-platelet therapy focused on peripheral blood cells of coronary arterial disease patients.
    Clinica chimica acta; international journal of clinical chemistry, 2013, Oct-21, Volume: 425

    Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug Administration Schedule; Gene Expression; Gene Expression Profiling; Humans; Insulin-Like Growth Factor I; Leukocytes, Mononuclear; Male; Middle Aged; Multidrug Resistance-Associated Proteins; Oligonucleotide Array Sequence Analysis; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptor, IGF Type 1; Ticlopidine; Treatment Outcome

2013
[Clopidogrel resistance of patients with coronary artery disease and its correlation with platelet count and mean platelet volume].
    Zhonghua yi xue za zhi, 2013, Mar-26, Volume: 93, Issue:12

    Topics: Aged; Clopidogrel; Coronary Artery Disease; Drug Resistance; Female; Humans; Male; Mean Platelet Volume; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Prospective Studies; Ticlopidine

2013
The place of newer oral anticoagulants in the treatment of patients with non-valvular atrial fibrillation and coronary artery disease.
    International journal of clinical practice, 2013, Volume: 67, Issue:8

    Topics: Administration, Oral; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Risk Factors; Stroke; Ticlopidine

2013
[Relationship between human platelet antigen-1 gene polymorphism and clopidogrel resistance in patients with coronary artery disease].
    Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir, 2013, Volume: 41, Issue:5

    Topics: Antigens, Human Platelet; Blood Platelets; Case-Control Studies; Clopidogrel; Coronary Artery Disease; Drug Resistance; Female; Genetic Predisposition to Disease; Humans; Integrin beta3; Male; Middle Aged; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Ticlopidine

2013
Effects of endothelial dysfunction on residual platelet aggregability after dual antiplatelet therapy with aspirin and clopidogrel in patients with stable coronary artery disease.
    Circulation. Cardiovascular interventions, 2013, Volume: 6, Issue:4

    Topics: Aged; Aryl Hydrocarbon Hydroxylases; Aspirin; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Endothelium, Vascular; Female; Humans; Linear Models; Logistic Models; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptors, Purinergic P2Y12; Ticlopidine

2013
P2RY12 gene polymorphisms and effect of clopidogrel on platelet aggregation.
    Collegium antropologicum, 2013, Volume: 37, Issue:2

    Topics: Aged; Clopidogrel; Coronary Artery Disease; Drug Resistance; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Receptors, Purinergic P2Y12; Ticlopidine

2013
Efficacy and safety of aspirin, clopidogrel, and warfarin after coronary artery stenting in Korean patients with atrial fibrillation.
    Heart and vessels, 2014, Volume: 29, Issue:5

    Topics: Aged; Anticoagulants; Asian People; Aspirin; Atrial Fibrillation; Blood Coagulation; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Disease-Free Survival; Drug Monitoring; Drug Therapy, Combination; Female; Hemorrhage; Humans; International Normalized Ratio; Kaplan-Meier Estimate; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Odds Ratio; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Proportional Hazards Models; Republic of Korea; Retrospective Studies; Risk Factors; Stents; Stroke; Ticlopidine; Time Factors; Treatment Outcome; Warfarin

2014
An allele-specific PCR system for rapid detection and discrimination of the CYP2C19∗4A, ∗4B, and ∗17 alleles: implications for clopidogrel response testing.
    The Journal of molecular diagnostics : JMD, 2013, Volume: 15, Issue:6

    Topics: Alleles; Aryl Hydrocarbon Hydroxylases; Base Sequence; Case-Control Studies; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Genetic Association Studies; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Polymerase Chain Reaction; Prodrugs; Reference Standards; Sensitivity and Specificity; Sequence Analysis, DNA; Ticlopidine

2013
Cilostazol--a forgotten antiplatelet agent, but does it even matter?
    JACC. Cardiovascular interventions, 2013, Volume: 6, Issue:9

    Topics: Cilostazol; Clopidogrel; Coronary Artery Disease; Drug-Eluting Stents; Female; Humans; Male; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Tetrazoles; Ticlopidine

2013
Comparison of the degree of platelet aggregation inhibition with prasugrel versus clopidogrel and clinical outcomes in patients with unprotected left main disease treated with everolimus-eluting stents.
    The American journal of cardiology, 2013, Dec-15, Volume: 112, Issue:12

    Topics: Aged; Aged, 80 and over; Clopidogrel; Coronary Artery Disease; Drug-Eluting Stents; Everolimus; Female; Humans; Immunosuppressive Agents; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Sirolimus; Thiophenes; Ticlopidine; Treatment Outcome

2013
Impact of initial clinical presentation on clopidogrel low response.
    Archives of cardiovascular diseases, 2013, Volume: 106, Issue:11

    Topics: Acute Coronary Syndrome; Aged; Blood Platelets; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Female; Humans; Linear Models; Logistic Models; Male; Middle Aged; Multivariate Analysis; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Prospective Studies; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome

2013
Clopidogrel results in favourable changes in nitric oxide metabolism in patients undergoing percutaneous coronary intervention.
    Thrombosis and haemostasis, 2014, Volume: 111, Issue:2

    Topics: Biomarkers; Clopidogrel; Coronary Artery Disease; Cyclic GMP; Humans; Nitrates; Nitric Oxide; Nitrites; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prospective Studies; Stents; Ticlopidine; Time Factors; Treatment Outcome; Vasodilation; Wales

2014
Impact of obesity and the metabolic syndrome on response to clopidogrel or prasugrel and bleeding risk in patients treated after coronary stenting.
    The American journal of cardiology, 2014, Jan-01, Volume: 113, Issue:1

    Topics: Aged; Clopidogrel; Coronary Artery Disease; Female; Humans; Incidence; Male; Metabolic Syndrome; Middle Aged; Obesity; Percutaneous Coronary Intervention; Piperazines; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Retrospective Studies; Stents; Thiophenes; Ticlopidine; United States

2014
Routine assessment of on-clopidogrel platelet reactivity and gene polymorphisms in predicting clinical outcome following drug-eluting stent implantation in patients with stable coronary artery disease.
    JACC. Cardiovascular interventions, 2013, Volume: 6, Issue:11

    Topics: Aged; Aryl Hydrocarbon Hydroxylases; Aspirin; Biotransformation; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Cytochrome P-450 CYP2C19; Decision Support Techniques; Drug Therapy, Combination; Drug-Eluting Stents; Female; Genotype; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Patient Selection; Percutaneous Coronary Intervention; Pharmacogenetics; Phenotype; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Polymorphism, Genetic; Predictive Value of Tests; Proportional Hazards Models; Risk Assessment; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome

2013
Spontaneous chest wall hematoma with dual antiplatelet therapy.
    The Canadian journal of cardiology, 2014, Volume: 30, Issue:2

    Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Follow-Up Studies; Hematoma; Humans; Male; Platelet Aggregation Inhibitors; Thoracic Wall; Ticlopidine; Tomography, X-Ray Computed

2014
Haemodialysis impairs clopidogrel but not aspirin responsiveness in patients with end-stage renal disease. Results of a pilot study.
    Thrombosis and haemostasis, 2014, Apr-01, Volume: 111, Issue:4

    Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Female; Follow-Up Studies; Humans; Kidney Failure, Chronic; Male; Middle Aged; Pilot Projects; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Receptors, Purinergic P2Y12; Renal Dialysis; Risk; Ticlopidine

2014
Impact of cigarette smoking on P2Y12 receptor binding activity before and after clopidogrel therapy in patients with coronary artery disease.
    Journal of cardiovascular translational research, 2014, Volume: 7, Issue:1

    Topics: Aged; Blood Platelets; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Pilot Projects; Platelet Aggregation Inhibitors; Radioligand Assay; Receptors, Purinergic P2Y12; Smoking; Ticlopidine; Treatment Outcome

2014
Bleeding risk with triple antithrombotic therapy in patients with atrial fibrillation and drug-eluting stents.
    Cardiovascular intervention and therapeutics, 2014, Volume: 29, Issue:3

    Topics: Aged; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Drug-Eluting Stents; Female; Hemorrhage; Humans; Male; Platelet Aggregation Inhibitors; Retrospective Studies; Risk Factors; Stroke; Thienopyridines; Ticlopidine; Warfarin

2014
The relationship between fractional flow reserve, platelet reactivity and platelet leukocyte complexes in stable coronary artery disease.
    PloS one, 2013, Volume: 8, Issue:12

    Topics: Aged; Blood Platelets; Clopidogrel; Coronary Artery Disease; Coronary Stenosis; Female; Fractional Flow Reserve, Myocardial; Humans; Leukocytes; Male; Middle Aged; Myocardial Ischemia; Platelet Activation; Platelet Aggregation Inhibitors; Prognosis; Ticlopidine

2013
Response to antiplatelet therapy and platelet reactivity to thrombin receptor activating peptide-6 in cardiovascular interventions: Differences between peripheral and coronary angioplasty.
    Atherosclerosis, 2014, Volume: 232, Issue:1

    Topics: Adenosine Diphosphate; Aged; Angioplasty; Angioplasty, Balloon, Coronary; Arachidonic Acid; Aspirin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Monocytes; P-Selectin; Peptide Fragments; Percutaneous Coronary Intervention; Peripheral Arterial Disease; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prognosis; Stents; Ticlopidine

2014
Association of thrombin generation potential with platelet PAR-1 regulation and P-selectin expression in patients on dual antiplatelet therapy.
    Journal of cardiovascular translational research, 2014, Volume: 7, Issue:1

    Topics: Adult; Aged; Aspirin; Biomarkers; Blood Platelets; Case-Control Studies; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; P-Selectin; Peptide Fragments; Piperazines; Platelet Activation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Prothrombin; Receptor, PAR-1; Thiophenes; Thrombin; Ticlopidine

2014
Antiplatelet therapy for stable coronary artery disease in atrial fibrillation patients taking an oral anticoagulant: a nationwide cohort study.
    Circulation, 2014, Apr-15, Volume: 129, Issue:15

    Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Cohort Studies; Comorbidity; Coronary Artery Disease; Drug Therapy, Combination; Female; Hemorrhage; Humans; Incidence; Male; Middle Aged; Myocardial Infarction; Phenprocoumon; Platelet Aggregation Inhibitors; Risk Factors; Stroke; Ticlopidine; Vitamin K; Warfarin

2014
Impact of chronic kidney disease on platelet reactivity and outcomes of patients receiving clopidogrel and undergoing percutaneous coronary intervention.
    The American journal of cardiology, 2014, Apr-01, Volume: 113, Issue:7

    Topics: Aged; Blood Platelets; Clopidogrel; Coronary Artery Disease; Electrocardiography; Female; Follow-Up Studies; Glomerular Filtration Rate; Humans; Male; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prognosis; Prospective Studies; Renal Insufficiency, Chronic; Ticlopidine

2014
Factor XIII Val34Leu polymorphism and recurrent myocardial infarction in patients with coronary artery disease.
    Journal of thrombosis and thrombolysis, 2014, Volume: 38, Issue:3

    Topics: Adult; Aged; Amino Acid Substitution; Aspirin; Clopidogrel; Coronary Artery Disease; Factor XIII; Female; Fibrin; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Thrombelastography; Ticlopidine

2014
Prevalence of CYP2C19 variant alleles and pharmacodynamic variability of aspirin and clopidogrel in Native Americans.
    American heart journal, 2014, Volume: 167, Issue:3

    Topics: Aged; Aryl Hydrocarbon Hydroxylases; Aspirin; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Female; Gene Frequency; Humans; Indians, North American; Male; Middle Aged; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Ticlopidine

2014
Triple versus dual antiplatelet therapy after percutaneous coronary intervention for coronary bifurcation lesions: results from the COBIS (COronary BIfurcation Stent) II Registry.
    Heart and vessels, 2015, Volume: 30, Issue:4

    Topics: Aged; Aspirin; Cilostazol; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Drug Therapy, Combination; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Logistic Models; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Republic of Korea; Retrospective Studies; Stroke; Tetrazoles; Ticlopidine; Treatment Outcome

2015
Prognostic value of bleeding after percutaneous coronary intervention in patients with diabetes.
    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2014, Volume: 10, Issue:1

    Topics: Abciximab; Aged; Antibodies, Monoclonal; Anticoagulants; Antithrombins; Aspirin; Clopidogrel; Coronary Artery Disease; Diabetes Mellitus, Type 2; Female; Hemorrhage; Heparin; Hirudins; Humans; Immunoglobulin Fab Fragments; Logistic Models; Male; Middle Aged; Peptide Fragments; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prognosis; Proportional Hazards Models; Recombinant Proteins; Risk Factors; Stents; Ticlopidine

2014
Increased mean platelet volume is associated with non-responsiveness to clopidogrel.
    Thrombosis and haemostasis, 2014, Jul-03, Volume: 112, Issue:1

    Topics: Adenosine Diphosphate; Blood Platelets; Cells, Cultured; Clopidogrel; Coronary Artery Disease; Drug Resistance; Female; Humans; Male; Mean Platelet Volume; Middle Aged; Platelet Aggregation; Platelet Count; Platelet Function Tests; Ticlopidine

2014
[Unexplained hypereosinophilia: too much or not enough?].
    Revue medicale suisse, 2014, Mar-12, Volume: 10, Issue:421

    Topics: Clopidogrel; Coronary Artery Disease; Eosinophilia; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine

2014
Association of P2Y12 gene promoter DNA methylation with the risk of clopidogrel resistance in coronary artery disease patients.
    BioMed research international, 2014, Volume: 2014

    Topics: Aged; Clopidogrel; Coronary Artery Disease; DNA Methylation; Drug Resistance; Female; Genetic Association Studies; Genetic Predisposition to Disease; Humans; Male; Middle Aged; Promoter Regions, Genetic; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Risk Factors; Ticlopidine; Treatment Failure

2014
Successful multidisciplinary treatment of hilar cholangiocarcinoma in a patient with complicated new-onset coronary artery disease.
    BMJ case reports, 2014, Apr-23, Volume: 2014

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Chemotherapy, Adjuvant; Cholangiocarcinoma; Clopidogrel; Combined Modality Therapy; Coronary Artery Disease; Hepatectomy; Humans; Jejunostomy; Male; Neoadjuvant Therapy; Platelet Aggregation Inhibitors; Stents; Ticlopidine

2014
Impact of CYP2C19 polymorphism on clinical outcome following coronary stenting is more important in non-diabetic than diabetic patients.
    Thrombosis research, 2014, Volume: 134, Issue:1

    Topics: Aged; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Diabetes Mellitus; Female; Genotype; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Prospective Studies; Stents; Ticlopidine

2014
Platelet factor XIIIa release during platelet aggregation and plasma clot strength measured by thrombelastography in patients with coronary artery disease treated with clopidogrel.
    Platelets, 2015, Volume: 26, Issue:4

    Topics: Blood Platelets; Clopidogrel; Coronary Artery Disease; Factor XIIIa; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombelastography; Ticlopidine

2015
Multi-parameter assessment of platelet inhibition and its stability during aspirin and clopidogrel therapy.
    Thrombosis research, 2014, Volume: 134, Issue:1

    Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine

2014
Posttreatment platelet reactivity on clopidogrel is associated with the risk of adverse events after off-pump coronary artery bypass.
    American heart journal, 2014, Volume: 167, Issue:6

    Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Cohort Studies; Coronary Artery Bypass, Off-Pump; Coronary Artery Disease; Drug Resistance; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Myocardial Infarction; Myocardial Revascularization; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; ROC Curve; Ticlopidine

2014
[Association between clopidogrel resistance and polymorphism of platelet adenosine diphosphate receptor in patients with coronary atherosclerotic disease].
    Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2014, Volume: 43, Issue:3

    Topics: Adolescent; Adult; Aged; Clopidogrel; Coronary Artery Disease; Drug Resistance; Female; Humans; Male; Middle Aged; Mutation; Polymorphism, Genetic; Prognosis; Receptors, Purinergic P2Y12; Ticlopidine; Young Adult

2014
The influence of body size on the pharmacodynamic and pharmacokinetic response to clopidogrel and prasugrel: a retrospective analysis of the FEATHER study.
    Thrombosis research, 2014, Volume: 134, Issue:3

    Topics: Adult; Aged; Biomarkers; Blood Platelets; Body Mass Index; Body Size; Body Surface Area; Body Weight; Cell Adhesion Molecules; Clopidogrel; Coronary Artery Disease; Drug Dosage Calculations; Female; Humans; Male; Microfilament Proteins; Middle Aged; Phosphoproteins; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Randomized Controlled Trials as Topic; Receptors, Purinergic P2Y12; Retrospective Studies; Ticlopidine; Treatment Outcome

2014
Comparison of loading with maintenance dose of clopidogrel on platelet reactivity in Chinese with different CYP2C19 genotypes prior to percutaneous coronary intervention.
    Chinese medical journal, 2014, Volume: 127, Issue:14

    Topics: Aged; Blood Platelets; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Female; Genotype; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation; Prospective Studies; Ticlopidine

2014
The chronovariability of platelet reactivity: a hurdle in the road to personalized antiplatelet therapy?
    Journal of the American College of Cardiology, 2014, Jul-29, Volume: 64, Issue:4

    Topics: Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Platelet Aggregation; Ticlopidine

2014
Single nucleotide polymorphism of CYP3A5*3 contributes to clopidogrel resistance in coronary artery disease patients among Tamilian population.
    Molecular biology reports, 2014, Volume: 41, Issue:11

    Topics: Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP3A; Drug Resistance; Ethnicity; Humans; India; Pharmacogenetics; Platelet Aggregation; Polymorphism, Single Nucleotide; Reverse Transcriptase Polymerase Chain Reaction; Ticlopidine

2014
Evidence of platelet sensitization to ADP following discontinuation of clopidogrel therapy in patients with stable coronary artery disease.
    Platelets, 2015, Volume: 26, Issue:6

    Topics: Adenosine Diphosphate; Aged; Blood Platelets; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine

2015
[Clinical impact of dual antiplatelet therapy on peptic ulcer disease].
    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2014, Volume: 64, Issue:2

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Drug Therapy, Combination; Female; Gastrointestinal Hemorrhage; Humans; Incidence; Male; Middle Aged; Peptic Ulcer; Platelet Aggregation Inhibitors; Proportional Hazards Models; Proton Pump Inhibitors; Retrospective Studies; Risk Factors; Ticlopidine

2014
Diabetes mellitus and clopidogrel response variability.
    Journal of the American College of Cardiology, 2014, Sep-09, Volume: 64, Issue:10

    Topics: Clopidogrel; Coronary Artery Disease; Diabetes Mellitus, Type 2; Female; Humans; Male; Platelet Aggregation; Purinergic P2Y Receptor Antagonists; Ticlopidine

2014
Impaired responsiveness to the platelet P2Y12 receptor antagonist clopidogrel in patients with type 2 diabetes and coronary artery disease.
    Journal of the American College of Cardiology, 2014, Sep-09, Volume: 64, Issue:10

    Topics: Adult; Aged; Aspirin; Clopidogrel; Cohort Studies; Coronary Artery Disease; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Purinergic P2Y Receptor Antagonists; Reference Values; Risk Assessment; Ticlopidine; Treatment Outcome

2014
Impact of clopidogrel plus aspirin versus aspirin alone on the progression of native coronary artery disease after bypass surgery: analysis from the Clopidogrel After Surgery for Coronary Artery DiseasE (CASCADE) randomized trial.
    Circulation, 2014, Sep-09, Volume: 130, Issue:11 Suppl 1

    Topics: Aged; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Bypass; Coronary Artery Disease; Coronary Restenosis; Coronary Stenosis; Diabetes Complications; Disease Progression; Double-Blind Method; Female; Follow-Up Studies; Humans; Male; Middle Aged; Multicenter Studies as Topic; Platelet Aggregation Inhibitors; Postoperative Complications; Randomized Controlled Trials as Topic; Risk Factors; Ticlopidine

2014
Association of Medicare Part D low-income cost subsidy program enrollment with increased fill adherence to clopidogrel after coronary stent placement.
    Pharmacotherapy, 2014, Volume: 34, Issue:12

    Topics: Aged; Clopidogrel; Coronary Artery Disease; Databases, Factual; Female; Humans; Insurance Benefits; Male; Medicare Part D; Middle Aged; Outcome Assessment, Health Care; Patient Compliance; Pharmaceutical Services; Platelet Aggregation Inhibitors; Stents; Ticlopidine; United States

2014
[Does dual antiplatelet therapy increase the risk of peptic ulcer disease?].
    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2014, Volume: 64, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Peptic Ulcer; Platelet Aggregation Inhibitors; Ticlopidine

2014
Effects of cytochrome P450 2C19 and paraoxonase 1 polymorphisms on antiplatelet response to clopidogrel therapy in patients with coronary artery disease.
    PloS one, 2014, Volume: 9, Issue:10

    Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Aryldialkylphosphatase; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Female; Genotype; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Ticlopidine

2014
Influence of race and sex on thrombogenicity in a large cohort of coronary artery disease patients.
    Journal of the American Heart Association, 2014, Oct-20, Volume: 3, Issue:5

    Topics: Aged; Aspirin; Cardiac Catheterization; Chi-Square Distribution; Clopidogrel; Cohort Studies; Coronary Angiography; Coronary Artery Disease; Female; Follow-Up Studies; Humans; Logistic Models; Male; Middle Aged; Multivariate Analysis; Platelet Aggregation; Platelet Function Tests; Racial Groups; Risk Assessment; Sex Factors; Thrombelastography; Thrombosis; Ticlopidine; Treatment Outcome

2014
Association of plasma miR-223 and platelet reactivity in patients with coronary artery disease on dual antiplatelet therapy: A preliminary report.
    Platelets, 2015, Volume: 26, Issue:6

    Topics: Aged; Aspirin; Biomarkers; Blood Platelets; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; MicroRNAs; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome

2015
Individualising dual antiplatelet therapy after percutaneous coronary intervention: the IDEAL-PCI registry.
    BMJ open, 2014, Oct-31, Volume: 4, Issue:10

    Topics: Acute Coronary Syndrome; Adenosine; Aged; Angioplasty, Balloon, Coronary; Aspirin; Blood Platelets; Clopidogrel; Cohort Studies; Coronary Artery Disease; Female; Graft Occlusion, Vascular; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Precision Medicine; Prospective Studies; Registries; Stents; Thiophenes; Ticagrelor; Ticlopidine

2014
Influence of dual antiplatelet therapy on mean platelet volume in patients with coronary artery disease undergoing percutaneous coronary intervention.
    Heart and vessels, 2016, Volume: 31, Issue:3

    Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug Monitoring; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Male; Mean Platelet Volume; Percutaneous Coronary Intervention; Platelet Activation; Platelet Aggregation Inhibitors; Predictive Value of Tests; Reproducibility of Results; Retrospective Studies; Ticlopidine; Time Factors; Treatment Outcome

2016
Impact of C34T P2Y12 genotype on endothelial function and arterial stiffness in patients after percutaneous coronary intervention receiving clopidogrel.
    International journal of cardiology, 2014, Dec-20, Volume: 177, Issue:3

    Topics: Aged; Clopidogrel; Coronary Artery Disease; Endothelium, Vascular; Female; Genotype; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Ticlopidine; Treatment Outcome; Vascular Stiffness

2014
Impact of diabetes mellitus and metabolic syndrome on acute and chronic on-clopidogrel platelet reactivity in patients with stable coronary artery disease undergoing drug-eluting stent placement.
    American heart journal, 2014, Volume: 168, Issue:6

    Topics: Aged; Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Artery Disease; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Monitoring; Drug-Eluting Stents; Female; France; Humans; Israel; Male; Metabolic Syndrome; Middle Aged; Odds Ratio; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prognosis; Prospective Studies; Ticlopidine

2014
High platelet reactivity is associated with vascular function in patients after percutaneous coronary intervention receiving clopidogrel.
    International journal of cardiology, 2014, Nov-15, Volume: 177, Issue:1

    Topics: Blood Platelets; Clopidogrel; Coronary Artery Disease; Female; Follow-Up Studies; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Postoperative Period; Prospective Studies; Ticlopidine

2014
Dual antiplatelet therapy in patients with a long coronary artery lesion over 30 mm: Determinants and impact on prognosis.
    Archives of cardiovascular diseases, 2015, Volume: 108, Issue:4

    Topics: Administration, Inhalation; Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Administration Schedule; Drug-Eluting Stents; Female; Humans; Kaplan-Meier Estimate; Linear Models; Male; Middle Aged; Multivariate Analysis; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Proportional Hazards Models; Retrospective Studies; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome

2015
Dual Antiplatelet Therapy Duration Following Coronary Stenting. [Corrected].
    Journal of the American College of Cardiology, 2015, Mar-03, Volume: 65, Issue:8

    Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Drug-Eluting Stents; Female; Hemorrhage; Humans; Male; Percutaneous Coronary Intervention; Ticlopidine

2015
Stent selection and antiplatelet therapy duration: one size does not fit all.
    Journal of the American College of Cardiology, 2015, Mar-03, Volume: 65, Issue:8

    Topics: Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Drug-Eluting Stents; Female; Hemorrhage; Humans; Male; Percutaneous Coronary Intervention; Postoperative Complications; Sirolimus; Ticlopidine

2015
Predictors of high on-aspirin platelet reactivity in high-risk vascular patients treated with single or dual antiplatelet therapy.
    The American journal of cardiology, 2015, May-01, Volume: 115, Issue:9

    Topics: Adenosine; Aged; Aspirin; Cerebrovascular Disorders; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Female; Fibrinogen; Humans; Male; Middle Aged; Piperazines; Platelet Activation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Predictive Value of Tests; Purinergic P2Y Receptor Antagonists; Retrospective Studies; Secondary Prevention; Thiophenes; Ticagrelor; Ticlopidine

2015
Influence of Different β-Blockers on Platelet Aggregation in Patients With Coronary Artery Disease on Dual Antiplatelet Therapy.
    Journal of cardiovascular pharmacology and therapeutics, 2016, Volume: 21, Issue:1

    Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Aspirin; Bisoprolol; Carbazoles; Carvedilol; Clopidogrel; Coronary Artery Disease; Drug Interactions; Drug Therapy, Combination; Female; Humans; Male; Metoprolol; Middle Aged; Nebivolol; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Propanolamines; Prospective Studies; Ticlopidine; Treatment Outcome

2016
Mean platelet volume and high-residual platelet reactivity in patients receiving dual antiplatelet therapy with clopidogrel or ticagrelor.
    Expert opinion on pharmacotherapy, 2015, Volume: 16, Issue:12

    Topics: Acute Coronary Syndrome; Adenosine; Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Female; Humans; Male; Mean Platelet Volume; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticagrelor; Ticlopidine

2015
Outcomes with prolonged clopidogrel therapy after coronary stenting in patients with chronic kidney disease.
    Heart (British Cardiac Society), 2015, Volume: 101, Issue:19

    Topics: Aged; Aged, 80 and over; Clopidogrel; Coronary Artery Disease; Drug Administration Schedule; Drug-Eluting Stents; Female; Glomerular Filtration Rate; Humans; Kidney; Male; Metals; Middle Aged; Multivariate Analysis; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Propensity Score; Proportional Hazards Models; Prosthesis Design; Renal Insufficiency, Chronic; Risk Assessment; Risk Factors; Stents; Ticlopidine; Time Factors; Treatment Outcome; United States; United States Department of Veterans Affairs

2015
Association of CYP2C19, CYP3A5 and GPIIb/IIIa gene polymorphisms with Aspirin and Clopidogrel Resistance in a cohort of Indian patients with Coronary Artery Disease.
    International journal of laboratory hematology, 2015, Volume: 37, Issue:6

    Topics: Aged; Alleles; Antigens, Human Platelet; Aspirin; Case-Control Studies; Clopidogrel; Cohort Studies; Comorbidity; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Drug Resistance; Female; Genotype; Humans; India; Integrin beta3; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Risk Factors; Ticlopidine; Treatment Outcome

2015
Optical coherence tomography analysis of the stent strut and prediction of resolved strut malapposition at 3 months after 2nd-generation drug-eluting stent implantation.
    Heart and vessels, 2016, Volume: 31, Issue:8

    Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Vessels; Drug-Eluting Stents; Everolimus; Female; Humans; Japan; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prosthesis Design; Sirolimus; Thrombosis; Ticlopidine; Tomography, Optical Coherence

2016
Long-Term Outcomes in Patients With Diabetes Mellitus Related to Prolonging Clopidogrel More Than 12 Months After Coronary Stenting.
    Journal of the American College of Cardiology, 2015, Sep-08, Volume: 66, Issue:10

    Topics: Aged; Analysis of Variance; Angioplasty, Balloon, Coronary; Cause of Death; Clopidogrel; Cohort Studies; Coronary Artery Disease; Databases, Factual; Diabetes Mellitus; Drug Administration Schedule; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Insulin; Long-Term Care; Male; Medicare; Middle Aged; Multivariate Analysis; Platelet Aggregation Inhibitors; Postoperative Care; Propensity Score; Proportional Hazards Models; Retrospective Studies; Risk Assessment; Severity of Illness Index; Survival Rate; Ticlopidine; Time Factors; Treatment Outcome; United States; Veterans Disability Claims

2015
Low platelet activity predicts 30 days mortality in patients undergoing heart surgery.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2016, Volume: 27, Issue:2

    Topics: Adenosine Diphosphate; Aged; Aortic Valve; Arachidonic Acid; Area Under Curve; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Erythrocyte Transfusion; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Prognosis; Retrospective Studies; Risk Factors; Survival Analysis; Thrombosis; Ticlopidine; Treatment Outcome

2016
Impact of Switching From Prasugrel to Clopidogrel Shortly After a Percutaneous Coronary Intervention Without a Loading Dose of Clopidogrel.
    The Journal of invasive cardiology, 2015, Volume: 27, Issue:12

    Topics: Clopidogrel; Coronary Angiography; Coronary Artery Disease; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Postoperative Care; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Retrospective Studies; Ticlopidine; Time Factors; Treatment Outcome

2015
Platelet Larger Cell Ratio and High-on Treatment Platelet Reactivity During Dual Antiplatelet Therapy.
    Cardiovascular drugs and therapy, 2015, Volume: 29, Issue:5

    Topics: Adenosine; Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticagrelor; Ticlopidine

2015
Successful Prasugrel Therapy for Recurrent Left Main Stent Thrombosis in a Clopidogrel Hyporesponder.
    Texas Heart Institute journal, 2015, Volume: 42, Issue:5

    Topics: Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Coronary Thrombosis; Drug Resistance; Drug Substitution; Drug Therapy, Combination; Drug-Eluting Stents; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Prosthesis Design; Recurrence; Ticlopidine; Time Factors; Treatment Outcome

2015
Concomitant nitrates enhance clopidogrel response during dual anti-platelet therapy.
    International journal of cardiology, 2016, Jan-15, Volume: 203

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Nitrates; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Ticlopidine; Time Factors; Treatment Outcome; Young Adult

2016
Premature Clopidogrel Discontinuation After Drug-Eluting Stent Placement in a Large Urban Safety-Net Hospital.
    The American journal of cardiology, 2016, Feb-15, Volume: 117, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Clopidogrel; Coronary Artery Disease; Drug-Eluting Stents; Female; Follow-Up Studies; Hospitals, Urban; Humans; Male; Middle Aged; Patient Compliance; Postoperative Period; Prognosis; Retrospective Studies; Ticlopidine; Time Factors; Withholding Treatment

2016
Clinical Value of CYP2C19 Genetic Testing for Guiding the Antiplatelet Therapy in a Chinese Population.
    Journal of cardiovascular pharmacology, 2016, Volume: 67, Issue:3

    Topics: Adenosine; Aged; Aged, 80 and over; Asian People; Biotransformation; Chi-Square Distribution; China; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Drug Monitoring; Female; Genotype; Hemorrhage; Humans; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Percutaneous Coronary Intervention; Pharmacogenomic Testing; Phenotype; Platelet Aggregation Inhibitors; Platelet Function Tests; Polymorphism, Genetic; Risk Factors; Ticagrelor; Ticlopidine; Treatment Outcome

2016
Assessment of platelet-derived thrombogenicity with the total thrombus-formation analysis system in coronary artery disease patients receiving antiplatelet therapy.
    Journal of thrombosis and haemostasis : JTH, 2016, Volume: 14, Issue:4

    Topics: Aged; Area Under Curve; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Cross-Sectional Studies; Cytochrome P-450 CYP2C19; Electrocardiography; Female; Genotype; Humans; Male; Middle Aged; Phenotype; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Polymorphism, Genetic; Thrombosis; Ticlopidine

2016
Clopidogrel Use as Single Antiplatelet Therapy in Outpatients with Stable Coronary Artery Disease: Prevalence, Correlates and Association with Prognosis (from the CORONOR Study).
    Cardiology, 2016, Volume: 134, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Drug-Eluting Stents; Endovascular Procedures; Female; France; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Outcome and Process Assessment, Health Care; Outpatients; Platelet Aggregation Inhibitors; Prevalence; Prognosis; Registries; Stroke; Ticlopidine

2016
Triple vs Dual Antithrombotic Therapy in Patients with Atrial Fibrillation and Coronary Artery Disease.
    The American journal of medicine, 2016, Volume: 129, Issue:6

    Topics: Administration, Oral; Aged; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Comorbidity; Coronary Artery Disease; Drug Therapy, Combination; Female; Fibrinolytic Agents; Hospitalization; Humans; Male; Markov Chains; Monte Carlo Method; Myocardial Infarction; Outcome and Process Assessment, Health Care; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Proportional Hazards Models; Pyridines; Registries; Stroke; Ticlopidine; Warfarin

2016
Association between high on-treatment platelet reactivity and occurrence of cerebral ischemic events in patients undergoing percutaneous coronary intervention.
    Thrombosis research, 2016, Volume: 138

    Topics: Adult; Aged; Aged, 80 and over; Blood Platelets; Brain Ischemia; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Polymorphism, Genetic; Risk Factors; Ticlopidine

2016
Prevalence and risk factors of clopidogrel non-response among Saudi patients undergoing coronary angiography.
    Saudi medical journal, 2016, Volume: 37, Issue:2

    Topics: Adult; Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Cross-Sectional Studies; Female; Humans; In Vitro Techniques; Logistic Models; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Odds Ratio; Platelet Aggregation Inhibitors; Prevalence; Risk Factors; Saudi Arabia; Ticlopidine; Treatment Failure

2016
Uric acid and high-residual platelet reactivity in patients treated with clopidogrel or ticagrelor.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2016, Volume: 26, Issue:4

    Topics: Adenosine; Aged; Aged, 80 and over; Blood Platelets; Clopidogrel; Coronary Artery Disease; Female; Fibrinogen; Humans; Male; Middle Aged; Multivariate Analysis; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Risk Factors; Ticagrelor; Ticlopidine; Triglycerides; Uric Acid

2016
Relationship Between Platelet Reactivity and Culprit Lesion Morphology: An Assessment From the ADAPT-DES Intravascular Ultrasound Substudy.
    JACC. Cardiovascular imaging, 2016, Volume: 9, Issue:7

    Topics: Aged; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Coronary Vessels; Drug Resistance; Drug-Eluting Stents; Female; Fibrosis; Germany; Humans; Least-Squares Analysis; Logistic Models; Male; Middle Aged; Multivariate Analysis; Percutaneous Coronary Intervention; Plaque, Atherosclerotic; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Prospective Studies; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome; Ultrasonography, Interventional; United States

2016
Impact of C34T P2Y12 ADP receptor polymorphism and smoking status on cardiovascular outcome in coronary artery disease patients receiving clopidogrel.
    International journal of cardiology, 2016, May-01, Volume: 210

    Topics: Aged; Clopidogrel; Coronary Artery Disease; Female; Follow-Up Studies; Humans; Male; Middle Aged; Polymorphism, Genetic; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Smoking; Ticlopidine; Treatment Outcome

2016
Outcomes According to Cardiac Catheterization Referral and Clopidogrel Use Among Medicare Patients With Non-ST-Segment Elevation Myocardial Infarction Discharged Without In-hospital Revascularization.
    Journal of the American Heart Association, 2016, Mar-14, Volume: 5, Issue:3

    Topics: Age Factors; Aged; Aged, 80 and over; Cardiac Catheterization; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Female; Humans; Male; Medicare; Myocardial Infarction; Myocardial Revascularization; Patient Discharge; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Referral and Consultation; Registries; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome; United States

2016
Effects of Arnica comp.-Heel® on reducing cardiovascular events in patients with stable coronary disease.
    Minerva cardioangiologica, 2016, Volume: 64, Issue:1

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Male; Middle Aged; Plants, Medicinal; Plaque, Atherosclerotic; Platelet Aggregation Inhibitors; Retrospective Studies; Secondary Prevention; Tablets; Ticlopidine; Treatment Outcome

2016
Trends in P2Y12 Inhibitor Use in Patients Referred for Invasive Evaluation of Coronary Artery Disease in Contemporary US Practice.
    The American journal of cardiology, 2016, May-01, Volume: 117, Issue:9

    Topics: Adenosine; Adult; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Female; Humans; Male; Percutaneous Coronary Intervention; Practice Patterns, Physicians'; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Referral and Consultation; Retrospective Studies; Ticagrelor; Ticlopidine; United States

2016
Parathyroid Hormone Levels and High-Residual Platelet Reactivity in Patients Receiving Dual Antiplatelet Therapy With Acetylsalicylic Acid and Clopidogrel or Ticagrelor.
    Cardiovascular therapeutics, 2016, Volume: 34, Issue:4

    Topics: Acute Coronary Syndrome; Adenosine; Adenosine Diphosphate; Aged; Aspirin; Biomarkers; Clopidogrel; Coronary Artery Disease; Databases, Factual; Drug Resistance; Drug Therapy, Combination; Female; Homeodomain Proteins; Humans; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Risk Factors; Ticagrelor; Ticlopidine; Time Factors; Transcription Factors; Treatment Outcome; Up-Regulation

2016
[Relationship between ATP-binding cassette subfamily B member 1 and cytochrome P450 2C19 polymorphisms and the effect of clopidogrel post percutaneous coronary intervention in patients with acute coronary syndrome].
    Zhonghua xin xue guan bing za zhi, 2016, Apr-24, Volume: 44, Issue:4

    Topics: Acute Coronary Syndrome; Alleles; Angina Pectoris; ATP Binding Cassette Transporter, Subfamily B; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Genotype; Hemorrhage; Humans; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Tandem Mass Spectrometry; Ticlopidine

2016
Continued vorapaxar versus withdrawed clopidogrel both on top of low dose aspirin in patients undergoing heart surgery: A call for randomized trial.
    International journal of cardiology, 2016, Jul-15, Volume: 215

    Topics: Aspirin; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Female; Humans; Lactones; Male; Myocardial Infarction; Postoperative Hemorrhage; Pyridines; Survival Analysis; Ticlopidine; Treatment Outcome

2016
Serum uric acid levels during dual antiplatelet therapy with ticagrelor or clopidogrel: Results from a single-centre study.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2016, Volume: 26, Issue:7

    Topics: Acute Coronary Syndrome; Adenosine; Aged; Aspirin; Biomarkers; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Female; Humans; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Risk Factors; Ticagrelor; Ticlopidine; Time Factors; Treatment Outcome; Up-Regulation; Uric Acid

2016
Hospital Variation in Premature Clopidogrel Discontinuation After Drug-Eluting Stent Placement in the Veterans Affairs (VA) Healthcare System.
    Journal of the American Heart Association, 2016, 05-05, Volume: 5, Issue:5

    Topics: Aftercare; Aged; Cardiology; Cause of Death; Clopidogrel; Coronary Artery Disease; Deprescriptions; Drug-Eluting Stents; Female; Hospitals; Humans; Male; Middle Aged; Mortality; Myocardial Infarction; Odds Ratio; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Practice Patterns, Physicians'; Proportional Hazards Models; Retrospective Studies; Risk Factors; Ticlopidine; Time Factors; United States; United States Department of Veterans Affairs

2016
Utility of the HAS-BLED Score in Risk Stratifying Patients on Dual Antiplatelet Therapy Post 12 Months After Drug-Eluting Stent Placement.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2017, Mar-01, Volume: 89, Issue:4

    Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Female; Follow-Up Studies; Georgia; Hemorrhage; Humans; Incidence; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Postoperative Period; Purinergic P2Y Receptor Antagonists; Retrospective Studies; Risk Assessment; Ticlopidine; Time Factors

2017
Exome sequencing of extreme clopidogrel response phenotypes identifies B4GALT2 as a determinant of on-treatment platelet reactivity.
    Clinical pharmacology and therapeutics, 2016, Volume: 100, Issue:3

    Topics: Adult; Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Drug Therapy, Combination; Exome; Female; Galactosyltransferases; Genotype; Humans; Male; Middle Aged; Phenotype; Pilot Projects; Platelet Aggregation Inhibitors; Ticlopidine

2016
Bleeding complications of triple antithrombotic therapy after percutaneous coronary interventions.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2017, Feb-01, Volume: 89, Issue:2

    Topics: Administration, Oral; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Coronary Artery Disease; Drug Administration Schedule; Drug Therapy, Combination; Female; Fibrinolytic Agents; Hemorrhage; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Ohio; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Proportional Hazards Models; Retrospective Studies; Risk Factors; Stents; Ticlopidine; Time Factors; Treatment Outcome; Warfarin

2017
[The incidence, clinical characteristics and risk factors of upper gastrointestinal bleeding in patients taking dual antiplatelet therapy after percutaneous coronary intervention in south China].
    Zhonghua nei ke za zhi, 2016, Volume: 55, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; China; Clopidogrel; Coronary Artery Disease; Female; Gastrointestinal Hemorrhage; Humans; Incidence; Male; Peptic Ulcer; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Retrospective Studies; Risk Factors; Ticlopidine; Upper Gastrointestinal Tract

2016
The first six-month clinical outcomes and risk factors associated with high on-treatment platelet reactivity of clopidogrel in patients undergoing coronary interventions.
    Anatolian journal of cardiology, 2016, Volume: 16, Issue:12

    Topics: Aged; Blood Platelets; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Risk Factors; Ticlopidine; Treatment Outcome; Turkey

2016
The Impact of Timing of Ischemic and Hemorrhagic Events on Mortality After Percutaneous Coronary Intervention: The ADAPT-DES Study.
    JACC. Cardiovascular interventions, 2016, 07-25, Volume: 9, Issue:14

    Topics: Aged; Aspirin; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug Therapy, Combination; Drug-Eluting Stents; Female; Germany; Hemorrhage; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Proportional Hazards Models; Prospective Studies; Registries; Risk Assessment; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome; United States

2016
Antithrombotic Medication Use and Misuse Among Patients with Intracranial Hemorrhage: A 16-Year, Lebanese, Single-Center Experience.
    World neurosurgery, 2016, Volume: 95

    Topics: Acenocoumarol; Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Cerebral Hemorrhage; Clopidogrel; Coronary Artery Disease; Enoxaparin; Female; Fibrinolytic Agents; Humans; Inappropriate Prescribing; Intracranial Hemorrhages; Lebanon; Male; Middle Aged; Platelet Aggregation Inhibitors; Prescription Drug Misuse; Retrospective Studies; Risk Factors; Stroke; Ticlopidine; Warfarin; Young Adult

2016
Predictors for Side Branch Failure During Provisional Strategy of Coronary Intervention for Bifurcation Lesions (from the Korean Bifurcation Registry).
    The American journal of cardiology, 2016, 09-15, Volume: 118, Issue:6

    Topics: Aged; Calcinosis; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Coronary Stenosis; Coronary Vessels; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Multivariate Analysis; Organ Size; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prognosis; Registries; Republic of Korea; Risk Factors; Ticlopidine; Treatment Failure

2016
Changes in response to clopidogrel therapy in patients after percutaneous coronary interventions as assessed by different platelet function tests.
    Polskie Archiwum Medycyny Wewnetrznej, 2016, Aug-18, Volume: 126, Issue:9

    Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine

2016
Vitamin D levels and high-residual platelet reactivity in patients receiving dual antiplatelet therapy with clopidogrel or ticagrelor.
    Platelets, 2016, Volume: 27, Issue:6

    Topics: Adenosine; Adenosine Diphosphate; Aged; Aged, 80 and over; Biomarkers; Blood Platelets; Clopidogrel; Comorbidity; Coronary Angiography; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Odds Ratio; Platelet Activation; Platelet Aggregation Inhibitors; Ticagrelor; Ticlopidine; Vitamin D

2016
Risk of bleeding after hospitalization for a serious coronary event: a retrospective cohort study with nested case-control analyses.
    BMC cardiovascular disorders, 2016, 08-30, Volume: 16, Issue:1

    Topics: Aged; Aged, 80 and over; Aspirin; Cerebral Hemorrhage; Clopidogrel; Confidence Intervals; Coronary Artery Disease; Drug Therapy, Combination; Female; Follow-Up Studies; Gastrointestinal Hemorrhage; Hospitalization; Humans; Incidence; Male; Middle Aged; Odds Ratio; Platelet Aggregation Inhibitors; Retrospective Studies; Risk Factors; Survival Rate; Ticlopidine; United Kingdom

2016
Determinants of agreement between proposed therapeutic windows of platelet function tests in vulnerable patients.
    European heart journal. Cardiovascular pharmacotherapy, 2017, Volume: 3, Issue:1

    Topics: Aged; Clopidogrel; Coronary Artery Disease; Female; Follow-Up Studies; Humans; Male; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Platelet Function Tests; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Retrospective Studies; Risk Factors; ROC Curve; Ticlopidine; Treatment Outcome; Vulnerable Populations

2017
The moving target of clopidogrel response variability: new tricks of the old dog?
    Polskie Archiwum Medycyny Wewnetrznej, 2016, 09-28, Volume: 126, Issue:9

    Topics: Clopidogrel; Coronary Artery Disease; Humans; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine

2016
Single versus double antiplatelet therapy in patients undergoing coronary artery bypass grafting with coronary endarterectomy: mid-term results and clinical implications.
    Interactive cardiovascular and thoracic surgery, 2017, 02-01, Volume: 24, Issue:2

    Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Drug Therapy, Combination; Endarterectomy; Female; Follow-Up Studies; Hospital Mortality; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Retrospective Studies; Ticlopidine; Treatment Outcome

2017
High platelet reactivity affects the clinical outcomes of patients undergoing percutaneous coronary intervention.
    BMC cardiovascular disorders, 2016, 11-29, Volume: 16, Issue:1

    Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug-Eluting Stents; Female; Follow-Up Studies; Graft Occlusion, Vascular; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Retrospective Studies; Ticlopidine; Time Factors

2016
Pharmacodynamic and cytogenetic evaluation in CYP2C19*2 and CYP2C19*3 allelomorphism in South Indian population with clopidogrel therapy.
    International journal of cardiology, 2017, Feb-15, Volume: 229

    Topics: Alleles; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; DNA; Female; Gene Frequency; Genotype; Humans; India; Male; Middle Aged; Pharmacogenetics; Phenotype; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Real-Time Polymerase Chain Reaction; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction; Ticlopidine; Treatment Outcome

2017
Clinical Pharmacogenetic Testing and Application: Laboratory Medicine Clinical Practice Guidelines.
    Annals of laboratory medicine, 2017, Volume: 37, Issue:2

    Topics: Anticoagulants; Antidepressive Agents; Antimetabolites, Antineoplastic; Antitubercular Agents; Arylamine N-Acetyltransferase; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Depressive Disorder; Genotype; Isoniazid; Laboratories, Hospital; Methyltransferases; Pharmacogenomic Testing; Platelet Aggregation Inhibitors; Pulmonary Embolism; Ticlopidine; Tuberculosis; Vitamin K Epoxide Reductases; Warfarin

2017
Impact of Cerebrovascular Events Older Than One Year on Ischemic and Bleeding Outcomes With Cangrelor in Percutaneous Coronary Intervention.
    Circulation. Cardiovascular interventions, 2017, Volume: 10, Issue:1

    Topics: Adenosine Monophosphate; Aged; Brain Ischemia; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Female; Hemorrhage; Humans; Ischemic Attack, Transient; Logistic Models; Male; Middle Aged; Myocardial Infarction; Odds Ratio; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Randomized Controlled Trials as Topic; Risk Assessment; Risk Factors; Stroke; Ticlopidine; Time Factors; Treatment Outcome

2017
Decreased platelet responsiveness to clopidogrel correlates with CYP2C19 and PON1 polymorphisms in atherosclerotic patients.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2017, 01-09, Volume: 50, Issue:1

    Topics: Alleles; Aryldialkylphosphatase; Aspirin; ATP Binding Cassette Transporter, Subfamily B; Blood Platelets; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Drug Therapy, Combination; Female; Genotype; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Prospective Studies; Ticlopidine

2017
Predictive value of non-fasting remnant cholesterol for short-term outcome of diabetics with new-onset stable coronary artery disease.
    Lipids in health and disease, 2017, Jan-13, Volume: 16, Issue:1

    Topics: Aged; Biomarkers; C-Reactive Protein; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Clopidogrel; Cohort Studies; Coronary Angiography; Coronary Artery Disease; Diabetes Mellitus, Type 2; Female; Fibrinogen; Follow-Up Studies; Glycated Hemoglobin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Neutrophils; Prognosis; Proportional Hazards Models; ROC Curve; Ticlopidine; Treatment Outcome

2017
The CYP2C19*2 and CYP2C19*17 Polymorphisms play a Vital Role in Clopidogrel Responsiveness after Percutaneous Coronary Intervention: A Pharmacogenomics Study.
    Basic & clinical pharmacology & toxicology, 2017, Volume: 121, Issue:1

    Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Female; Gene Frequency; Genotype; Humans; Male; Middle Aged; Myocardial Ischemia; Percutaneous Coronary Intervention; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Postoperative Complications; Sequence Analysis, DNA; Stents; Thrombosis; Ticlopidine; Treatment Outcome; Turkey

2017
Platelet reactivity in patients carrying the e-NOS G894T polymorphism after a loading dose of aspirin plus clopidogrel.
    Thrombosis research, 2017, Volume: 151

    Topics: Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Humans; Nitric Oxide; Nitric Oxide Synthase Type III; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Ticlopidine

2017
Dual Antiplatelet Therapy and Clinical Outcomes after Coronary Drug-Eluting Stent Implantation in Patients on Hemodialysis.
    Clinical journal of the American Society of Nephrology : CJASN, 2017, 02-07, Volume: 12, Issue:2

    Topics: Aged; Aspirin; Brain Ischemia; Case-Control Studies; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Drug-Eluting Stents; Female; Hemorrhage; Humans; Kaplan-Meier Estimate; Kidney Failure, Chronic; Male; Middle Aged; Myocardial Infarction; Myocardial Revascularization; Platelet Aggregation Inhibitors; Propensity Score; Renal Dialysis; Retrospective Studies; Stroke; Survival Rate; Taiwan; Ticlopidine

2017
Sex Differences in the Clinical Impact of High Platelet Reactivity After Percutaneous Coronary Intervention With Drug-Eluting Stents: Results From the ADAPT-DES Study (Assessment of Dual Antiplatelet Therapy With Drug-Eluting Stents).
    Circulation. Cardiovascular interventions, 2017, Volume: 10, Issue:2

    Topics: Aged; Aspirin; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug Resistance; Drug Therapy, Combination; Drug-Eluting Stents; Female; Germany; Hemorrhage; Humans; Kaplan-Meier Estimate; Logistic Models; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Propensity Score; Prospective Studies; Purinergic P2Y Receptor Antagonists; Registries; Risk Factors; Sex Factors; Ticlopidine; Time Factors; Treatment Outcome; United States

2017
Longer-term oral antiplatelet use in stable post-myocardial infarction patients: Insights from the long Term rIsk, clinical manaGement and healthcare Resource utilization of stable coronary artery dISease (TIGRIS) observational study.
    International journal of cardiology, 2017, Jun-01, Volume: 236

    Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Drug-Eluting Stents; Female; Humans; International Cooperation; Long Term Adverse Effects; Male; Middle Aged; Outcome Assessment, Health Care; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Risk Factors; ST Elevation Myocardial Infarction; Ticlopidine

2017
Platelet Reactivity and Clinical Outcomes After Coronary Artery Implantation of Drug-Eluting Stents in Subjects With Peripheral Arterial Disease: Analysis From the ADAPT-DES Study (Assessment of Dual Antiplatelet Therapy With Drug-Eluting Stents).
    Circulation. Cardiovascular interventions, 2017, Volume: 10, Issue:3

    Topics: Aged; Aspirin; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug Therapy, Combination; Drug-Eluting Stents; Female; Hemorrhage; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Percutaneous Coronary Intervention; Peripheral Arterial Disease; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Propensity Score; Proportional Hazards Models; Prospective Studies; Purinergic P2Y Receptor Antagonists; Registries; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome

2017
[Platelet Metabolism in Clopidogrel Resistant and Sensitive Patients With Ischemic Heart Disease].
    Kardiologiia, 2016, Volume: 56, Issue:10

    Topics: Aged; Blood Platelets; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Drug Resistance; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine

2016
Long-term outcomes by clopidogrel duration and stent type in a diabetic population with de novo coronary artery lesions.
    Journal of the American College of Cardiology, 2008, Jun-10, Volume: 51, Issue:23

    Topics: Clopidogrel; Coronary Artery Disease; Diabetes Mellitus; Disease Progression; Drug-Eluting Stents; Female; Humans; Incidence; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Odds Ratio; Platelet Aggregation Inhibitors; Retrospective Studies; Risk Factors; Survival Analysis; Ticlopidine; Time Factors; Treatment Outcome

2008
The evolution of thienopyridine therapy clopidogrel duration, diabetes, and drug-eluting stents.
    Journal of the American College of Cardiology, 2008, Jun-10, Volume: 51, Issue:23

    Topics: Clopidogrel; Coronary Artery Disease; Diabetes Mellitus; Disease Progression; Drug-Eluting Stents; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Pyridines; Ticlopidine; Time Factors; Treatment Outcome

2008
The primary and secondary prevention of coronary artery disease: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition).
    Chest, 2008, Volume: 133, Issue:6 Suppl

    Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Evidence-Based Medicine; Fibrinolytic Agents; Humans; Primary Prevention; Risk Assessment; Risk Factors; Ticlopidine

2008
Clopidogrel but not Aspirin prevents acute smoking-induced platelet aggregation in patients with stable coronary artery disease.
    Thrombosis research, 2009, Volume: 123, Issue:4

    Topics: Adult; Aspirin; Clopidogrel; Coronary Artery Disease; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Smoking; Ticlopidine

2009
Baseline platelet activity and response after clopidogrel in 257 diabetics among 822 patients with coronary artery disease.
    Thrombosis and haemostasis, 2008, Volume: 100, Issue:1

    Topics: Aged; Aspirin; Baltimore; Biomarkers; Clopidogrel; Coronary Artery Disease; Diabetes Mellitus; Female; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine; Treatment Outcome

2008
Aspirin resistance an underestimated risk in patients with drug-eluting stents?
    Journal of the American College of Cardiology, 2008, Aug-26, Volume: 52, Issue:9

    Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Drug Resistance; Drug-Eluting Stents; Graft Occlusion, Vascular; Humans; Platelet Activation; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine

2008
Dual antiplatelet therapy unmasks distinct platelet reactivity in patients with coronary artery disease.
    Journal of thrombosis and haemostasis : JTH, 2008, Volume: 6, Issue:12

    Topics: Adenosine Diphosphate; Aged; Aspirin; Case-Control Studies; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Epinephrine; Female; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine

2008
Unprotected left main coronary artery bifurcation stenosis: impact of plaque debulking prior to single sirolimus-eluting stent implantation.
    The Journal of invasive cardiology, 2008, Volume: 20, Issue:10

    Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Vessels; Drug-Eluting Stents; Feasibility Studies; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Prospective Studies; Risk Factors; Sirolimus; Ticlopidine

2008
Identifying clopidogrel resistance during chronic therapy: the case for a biochemical approach.
    Thrombosis and haemostasis, 2008, Volume: 100, Issue:4

    Topics: Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Stents; Ticlopidine

2008
Adrenoreceptors, platelet reactivity and clopidogrel resistance.
    Thrombosis and haemostasis, 2008, Volume: 100, Issue:5

    Topics: Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug Resistance; Drug Therapy, Combination; Humans; Norepinephrine; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Receptors, Adrenergic, alpha-2; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Ticlopidine; Treatment Failure

2008
Analysis of platelet alpha2-adrenergic receptor activity in stable coronary artery disease patients on dual antiplatelet therapy.
    Thrombosis and haemostasis, 2008, Volume: 100, Issue:5

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adrenergic alpha-Antagonists; Aged; Aspirin; Blood Platelets; Clopidogrel; Collagen; Coronary Artery Disease; Drug Resistance; Drug Therapy, Combination; Female; Humans; Imidazoles; Male; Middle Aged; Norepinephrine; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Receptors, Adrenergic, alpha-2; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Ticlopidine; Treatment Failure

2008
Measurement of the platelet retention rate in a column of collagen-coated beads is useful for the assessment of efficacy of antiplatelet therapy.
    Thrombosis research, 2009, Volume: 123, Issue:6

    Topics: Aged; Aspirin; Blood Platelets; Cell Separation; Clopidogrel; Collagen; Coronary Artery Disease; Female; Humans; In Vitro Techniques; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine; Treatment Outcome

2009
The pursuit of clinically relevant measures of platelet function after antiplatelet drug therapy.
    Journal of the American College of Cardiology, 2008, Dec-09, Volume: 52, Issue:24

    Topics: Blood Platelets; Clopidogrel; Coronary Artery Disease; Diabetes Complications; Humans; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Pyridines; Risk Factors; Thiophenes; Ticlopidine; Treatment Failure

2008
Gemcitabine-induced acute coronary syndrome: a case report.
    Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2009, Volume: 18, Issue:1

    Topics: Antimetabolites, Antineoplastic; Aspirin; Bundle-Branch Block; Clopidogrel; Coronary Artery Disease; Coronary Vasospasm; Deoxycytidine; Electrocardiography; Fatal Outcome; Female; Gemcitabine; Humans; Leiomyosarcoma; Lung Neoplasms; Middle Aged; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine

2009
Impact of "nuisance" bleeding on clopidogrel compliance in patients undergoing intracoronary drug-eluting stent implantation.
    The American journal of cardiology, 2008, Dec-15, Volume: 102, Issue:12

    Topics: Aged; Angioplasty, Balloon, Coronary; Clopidogrel; Contusions; Coronary Angiography; Coronary Artery Disease; Drug-Eluting Stents; Female; Hemorrhage; Humans; Incidence; Male; Middle Aged; Observation; Patient Compliance; Platelet Aggregation Inhibitors; Severity of Illness Index; Ticlopidine

2008
The treatment of clopidogrel resistance: triple antiplatelet therapy and future directions.
    International journal of cardiology, 2010, Sep-24, Volume: 144, Issue:1

    Topics: Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Ticlopidine

2010
The effect of antiplatelet drugs clopidogrel and aspirin is less immediately after stent implantation.
    Thrombosis research, 2009, Volume: 123, Issue:6

    Topics: Aged; Angioplasty, Balloon, Coronary; Antiplatyhelmintic Agents; Aspirin; Cell Adhesion Molecules; Clopidogrel; Coronary Artery Disease; Female; Heparin; Humans; In Vitro Techniques; Male; Microfilament Proteins; Middle Aged; Phosphoproteins; Platelet Aggregation; Platelet Function Tests; Stents; Ticlopidine; Time Factors; von Willebrand Factor

2009
Impact of high loading and maintenance dose of clopidogrel within the first 15 days after percutaneous coronary intervention on patient outcome.
    American heart journal, 2009, Volume: 157, Issue:2

    Topics: Aged; Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Stents; Ticlopidine; Time Factors; Treatment Outcome

2009
Ischaemia versus bleeding: the art of clinical decision-making.
    Lancet (London, England), 2009, Feb-28, Volume: 373, Issue:9665

    Topics: Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Artery Disease; Decision Making; Hemorrhage; Humans; Myocardial Infarction; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Randomized Controlled Trials as Topic; Thiophenes; Ticlopidine

2009
Evaluation of the platelet count drop method for assessment of platelet function in comparison with "gold standard" light transmission aggregometry.
    Thrombosis research, 2009, Volume: 124, Issue:4

    Topics: Adenosine Diphosphate; Aged; Arachidonic Acid; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Platelet Function Tests; Reproducibility of Results; Ticlopidine

2009
Platelet reactivity after clopidogrel treatment assessed with point-of-care analysis and early drug-eluting stent thrombosis.
    Journal of the American College of Cardiology, 2009, Mar-10, Volume: 53, Issue:10

    Topics: Aged; Clopidogrel; Coronary Artery Disease; Drug-Eluting Stents; Electric Impedance; Electrodes; Female; Humans; Kaplan-Meier Estimate; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Point-of-Care Systems; Prospective Studies; Thrombosis; Ticlopidine

2009
Point-of-care platelet function analysis ready for prime time?
    Journal of the American College of Cardiology, 2009, Mar-10, Volume: 53, Issue:10

    Topics: Clopidogrel; Coronary Artery Disease; Drug-Eluting Stents; Hemorrhage; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Point-of-Care Systems; Thrombosis; Ticlopidine

2009
The ischaemia/bleeding balance in PCI.
    Lancet (London, England), 2009, Mar-14, Volume: 373, Issue:9667

    Topics: Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Artery Disease; Hemorrhage; Humans; Lactones; Platelet Aggregation Inhibitors; Pyridines; Randomized Controlled Trials as Topic; Receptors, Thrombin; Severity of Illness Index; Thrombin; Ticlopidine

2009
Prolonged dual antiplatelet therapy improves clinical outcomes in high-risk patients implanted with sirolimus-eluting stents.
    Clinical cardiology, 2009, Volume: 32, Issue:3

    Topics: Aspirin; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Drug-Eluting Stents; Female; Graft Occlusion, Vascular; Humans; Immunosuppressive Agents; Male; Platelet Aggregation Inhibitors; Retrospective Studies; Sirolimus; Ticlopidine; Treatment Outcome

2009
Clopidogrel pretreatment before primary percutaneous coronary stenting in patients with acute ST-segment elevation myocardial infarction: comparison of high loading dose (600 mg) versus low loading dose (300 mg).
    Coronary artery disease, 2009, Volume: 20, Issue:2

    Topics: Aged; Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Artery Disease; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Retrospective Studies; Stents; Stroke; Ticlopidine; Time Factors; Treatment Outcome

2009
Does the Holy Grail escape us again?
    European heart journal, 2009, Volume: 30, Issue:9

    Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Humans; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine

2009
Treatment of multilesion coronary artery disease with simultaneous drug-eluting and bare-metal stent implantation: clinical follow up and angiographic mid-term results.
    The Journal of invasive cardiology, 2009, Volume: 21, Issue:4

    Topics: Abciximab; Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Anticoagulants; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Coronary Restenosis; Coronary Vessels; Databases as Topic; Drug-Eluting Stents; Drug-Related Side Effects and Adverse Reactions; Female; Heparin; Humans; Immunoglobulin Fab Fragments; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Stents; Ticlopidine; Time Factors; Treatment Outcome

2009
Spontaneous coronary artery dissection and severe hypothyroidism.
    The Journal of invasive cardiology, 2009, Volume: 21, Issue:4

    Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Vessels; Eptifibatide; Fatal Outcome; Female; Humans; Hypothyroidism; Neck Pain; Peptides; Platelet Aggregation Inhibitors; Ticlopidine

2009
Clopidogrel and proton pump inhibitors: gastric protection at expense of vascular benefit?
    Thrombosis and haemostasis, 2009, Volume: 101, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenosine Diphosphate; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Drug Interactions; Drug Therapy, Combination; Humans; Omeprazole; Pantoprazole; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Proton Pump Inhibitors; Stents; Ticlopidine

2009
Impact of proton pump inhibitors on the antiplatelet effects of clopidogrel.
    Thrombosis and haemostasis, 2009, Volume: 101, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Cross-Sectional Studies; Drug Interactions; Drug Therapy, Combination; Esomeprazole; Female; Humans; Male; Middle Aged; Multivariate Analysis; Omeprazole; Pantoprazole; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Proton Pump Inhibitors; Stents; Ticlopidine

2009
Early, accurate, non-invasive predictors of left main or 3-vessel disease in patients with non-ST-segment elevation acute coronary syndrome.
    Circulation journal : official journal of the Japanese Circulation Society, 2009, Volume: 73, Issue:6

    Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Electrocardiography; Female; Humans; Male; Middle Aged; Multivariate Analysis; Platelet Aggregation Inhibitors; Predictive Value of Tests; Prognosis; Retrospective Studies; Sensitivity and Specificity; Ticlopidine; Troponin T

2009
Use of a thrombelastograph platelet mapping assay for diagnosis of clopidogrel resistance: a case report.
    The journal of extra-corporeal technology, 2009, Volume: 41, Issue:1

    Topics: Abciximab; Antibodies, Monoclonal; Anticoagulants; Blood Platelets; Cardiac Catheterization; Clopidogrel; Coronary Artery Disease; Drug Resistance; Female; Fibrinolytic Agents; Humans; Immunoglobulin Fab Fragments; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Stents; Thrombelastography; Ticlopidine; Warfarin

2009
Incidence of stent thrombosis in patients with drug eluting stents and short-term dual antiplatelet therapy.
    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2009, Volume: 4, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Agents; Clopidogrel; Coronary Artery Disease; Databases as Topic; Drug Administration Schedule; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Incidence; Kaplan-Meier Estimate; Male; Medication Adherence; Middle Aged; Paclitaxel; Platelet Aggregation Inhibitors; Sirolimus; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome

2009
Combined carotid stenting and urgent coronary artery surgery in unstable angina patients with severe carotid stenosis.
    Interactive cardiovascular and thoracic surgery, 2009, Volume: 9, Issue:2

    Topics: Aged; Aged, 80 and over; Angina, Unstable; Angioplasty, Balloon; Anticoagulants; Aspirin; Carotid Stenosis; Clopidogrel; Coronary Artery Bypass; Coronary Artery Bypass, Off-Pump; Coronary Artery Disease; Drug Administration Schedule; Female; Heparin; Humans; Male; Platelet Aggregation Inhibitors; Risk Assessment; Severity of Illness Index; Stents; Ticlopidine; Time Factors; Treatment Outcome

2009
Stent thrombosis, clinical events, and influence of prolonged clopidogrel use after placement of drug-eluting stent data from an observational cohort study of drug-eluting versus bare-metal stents.
    JACC. Cardiovascular interventions, 2008, Volume: 1, Issue:5

    Topics: Aged; Angioplasty, Balloon, Coronary; Clopidogrel; Cohort Studies; Coronary Artery Disease; Drug Administration Schedule; Drug-Eluting Stents; Female; Humans; Kaplan-Meier Estimate; Korea; Male; Metals; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Proportional Hazards Models; Prosthesis Design; Risk Assessment; Stents; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome

2008
Preliminary results of the hydroxyapatite nonpolymer-based sirolimus-eluting stent for the treatment of single de novo coronary lesions a first-in-human analysis of a third-generation drug-eluting stent system.
    JACC. Cardiovascular interventions, 2008, Volume: 1, Issue:5

    Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Agents; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Coronary Restenosis; Coronary Thrombosis; Drug-Eluting Stents; Durapatite; Female; Humans; Male; Middle Aged; Pilot Projects; Platelet Aggregation Inhibitors; Prosthesis Design; Registries; Sirolimus; Stainless Steel; Ticlopidine; Time Factors; Treatment Outcome; Ultrasonography, Interventional

2008
Searching for the ceiling: new reflections on the disposition and metabolism of clopidogrel.
    JACC. Cardiovascular interventions, 2008, Volume: 1, Issue:6

    Topics: Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood Platelets; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance; Genotype; Humans; Phenotype; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Stents; Thrombosis; Ticlopidine

2008
The excel stent: a good DES, but can we really stop clopidogrel after 6 months?
    JACC. Cardiovascular interventions, 2009, Volume: 2, Issue:4

    Topics: Angioplasty, Balloon, Coronary; Aspirin; Cardiovascular Agents; Clopidogrel; Coated Materials, Biocompatible; Coronary Artery Disease; Coronary Restenosis; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Humans; Platelet Aggregation Inhibitors; Polymers; Prosthesis Design; Risk Assessment; Sirolimus; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome

2009
Simultaneous hybrid revascularization by carotid stenting and coronary artery bypass grafting: the SHARP study.
    JACC. Cardiovascular interventions, 2009, Volume: 2, Issue:5

    Topics: Aged; Angioplasty, Balloon, Coronary; Carotid Arteries; Carotid Artery Diseases; Clopidogrel; Coronary Artery Bypass, Off-Pump; Coronary Artery Disease; Drug-Eluting Stents; Female; Humans; Male; Platelet Aggregation Inhibitors; Prospective Studies; Ticlopidine; Time Factors; Tomography, X-Ray Computed

2009
1-year results of the hydroxyapatite polymer-free sirolimus-eluting stent for the treatment of single de novo coronary lesions: the VESTASYNC I trial.
    JACC. Cardiovascular interventions, 2009, Volume: 2, Issue:5

    Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Bypass; Coronary Artery Disease; Coronary Restenosis; Drug-Eluting Stents; Durapatite; Female; Humans; Intensive Care Units; Male; Middle Aged; Platelet Aggregation Inhibitors; Polymers; Prospective Studies; Sirolimus; Ticlopidine; Time Factors; Ultrasonography

2009
Coronary artery disease: Platelet activity: an obstacle for successful PCI.
    Nature reviews. Cardiology, 2009, Volume: 6, Issue:6

    Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Humans; Patient Selection; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Risk Assessment; Risk Factors; Stents; Thrombosis; Ticlopidine; Treatment Outcome

2009
Development and validation of a risk scoring model to predict net adverse cardiovascular outcomes after primary percutaneous coronary intervention in patients pretreated with 600 mg clopidogrel: rationale and design of the RISK-PCI study.
    Journal of interventional cardiology, 2009, Volume: 22, Issue:4

    Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Female; Humans; Kaplan-Meier Estimate; Logistic Models; Longitudinal Studies; Male; Middle Aged; Models, Statistical; Models, Theoretical; Multivariate Analysis; Platelet Aggregation Inhibitors; Research Design; Risk Assessment; Risk Factors; ROC Curve; Ticlopidine; Treatment Outcome

2009
The in-vitro effects of E5555, a protease-activated receptor (PAR)-1 antagonist, on platelet biomarkers in healthy volunteers and patients with coronary artery disease.
    Thrombosis and haemostasis, 2009, Volume: 102, Issue:1

    Topics: Aged; Aspirin; Biomarkers; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug Synergism; Female; Flow Cytometry; Humans; Imines; In Vitro Techniques; Male; Middle Aged; Platelet Aggregation Inhibitors; Pyridines; Receptor, PAR-1; Thrombosis; Ticlopidine

2009
Platelet reactivity and stent thrombosis: still some issues to solve.
    Journal of the American College of Cardiology, 2009, Aug-11, Volume: 54, Issue:7

    Topics: Angioplasty, Balloon, Coronary; Clopidogrel; Comorbidity; Coronary Artery Disease; Drug-Eluting Stents; Electrodes; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Risk Assessment; Smoking; Thrombosis; Ticlopidine

2009
Prevalence and risk factors for aspirin and clopidogrel resistance in patients with coronary artery disease or ischemic cerebrovascular disease.
    Annals of clinical and laboratory science, 2009,Summer, Volume: 39, Issue:3

    Topics: Aged; Aspirin; Blood Pressure; Cerebral Arterial Diseases; Clopidogrel; Coronary Artery Disease; Drug Resistance; Female; Hemoglobins; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Prevalence; Risk Factors; Ticlopidine

2009
Challenge. What is your diagnosis? Answer. Primary nodal diffuse large B-cell lymphoma with secondary cutaneous involvement.
    The American Journal of dermatopathology, 2009, Volume: 31, Issue:7

    Topics: Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Clopidogrel; Coronary Artery Disease; Diuretics; Exanthema; Humans; Hydrochlorothiazide; Lisinopril; Lymphoma, Large B-Cell, Diffuse; Male; Platelet Aggregation Inhibitors; Skin Neoplasms; Sotalol; Stents; Ticlopidine

2009
The carina angle-new geometrical parameter associated with periprocedural side branch compromise and the long-term results in coronary bifurcation lesions with main vessel stenting only.
    Journal of interventional cardiology, 2009, Volume: 22, Issue:6

    Topics: Aged; Analysis of Variance; Antineoplastic Agents, Phytogenic; Clopidogrel; Confidence Intervals; Coronary Angiography; Coronary Artery Disease; Coronary Restenosis; Coronary Vessels; Drug-Eluting Stents; Everolimus; Female; Humans; Image Interpretation, Computer-Assisted; Immunosuppressive Agents; Male; Mathematics; Multivariate Analysis; Odds Ratio; Paclitaxel; Platelet Aggregation Inhibitors; Poland; Registries; Retrospective Studies; Sirolimus; Statistics as Topic; Ticlopidine; Time Factors

2009
Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy.
    JAMA, 2009, Aug-26, Volume: 302, Issue:8

    Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Chromosomes, Human, Pair 10; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Ethnicity; Female; Genome-Wide Association Study; Genotype; Humans; Male; Middle Aged; Pharmacogenetics; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Ticlopidine; Treatment Outcome

2009
Tailoring antiplatelet therapy based on pharmacogenomics: how well do the data fit?
    JAMA, 2009, Aug-26, Volume: 302, Issue:8

    Topics: Aryl Hydrocarbon Hydroxylases; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Humans; Pharmacogenetics; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine

2009
One-year follow-up of nonrandomized comparison between coronary artery bypass grafting surgery and drug-eluting stent for the treatment of unprotected left main coronary artery disease in elderly patients (aged >or=75 years).
    Journal of interventional cardiology, 2009, Volume: 22, Issue:6

    Topics: Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Confidence Intervals; Coronary Artery Bypass; Coronary Artery Disease; Drug-Eluting Stents; Female; Heparin; Humans; Logistic Models; Male; Multivariate Analysis; Odds Ratio; Platelet Aggregation Inhibitors; Prospective Studies; Stroke Volume; Ticlopidine; Time Factors; Ventricular Function, Left

2009
Side balloon stenting of the left main bifurcation: a three-year angiographic follow-up.
    Journal of interventional cardiology, 2009, Volume: 22, Issue:6

    Topics: Angioplasty, Balloon, Coronary; Antineoplastic Agents, Phytogenic; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Coronary Restenosis; Drug-Eluting Stents; Humans; Male; Middle Aged; Paclitaxel; Platelet Aggregation Inhibitors; Prospective Studies; Ticlopidine; Time Factors

2009
Femoral artery complications after cardiac catheterization: a study of patient profile.
    Annals of vascular surgery, 2010, Volume: 24, Issue:3

    Topics: Aged; Anticoagulants; Cardiac Catheterization; Clopidogrel; Coronary Artery Disease; Female; Femoral Artery; Hematoma; Hemorrhage; Hemostatic Techniques; Heparin; Humans; Logistic Models; Male; Middle Aged; Odds Ratio; Platelet Aggregation Inhibitors; Punctures; Retrospective Studies; Risk Assessment; Risk Factors; Sex Factors; Ticlopidine

2010
Effect of comedication with proton pump inhibitors (PPIs) on post-interventional residual platelet aggregation in patients undergoing coronary stenting treated by dual antiplatelet therapy.
    Thrombosis research, 2010, Volume: 125, Issue:2

    Topics: Aged; Angioplasty, Balloon, Coronary; Clopidogrel; Cohort Studies; Coronary Artery Disease; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Propensity Score; Proton Pump Inhibitors; Retrospective Studies; Stents; Ticlopidine; Treatment Outcome

2010
Early but not late stent thrombosis is influenced by residual platelet aggregation in patients undergoing coronary interventions.
    European heart journal, 2010, Volume: 31, Issue:1

    Topics: Adolescent; Adult; Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Drug-Eluting Stents; Graft Occlusion, Vascular; Humans; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Treatment Outcome; Young Adult

2010
Prevalence of unresponsiveness to aspirin and/or clopidogrel in patients with stable coronary heart disease.
    The American journal of cardiology, 2009, Nov-01, Volume: 104, Issue:9

    Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Point-of-Care Systems; Ticlopidine

2009
[Basic examination before clinical examination. That is why it is worthwhile to return to the laboratory].
    Kardiologia polska, 2009, Volume: 67, Issue:6

    Topics: Aspirin; Biomarkers; Blood Coagulation; CD40 Ligand; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Humans; P-Selectin; Platelet Activation; Platelet Aggregation Inhibitors; Punctures; Thrombin; Ticlopidine; Veins

2009
Correlation of inhibition of platelet aggregation after clopidogrel with post discharge bleeding events: assessment by different bleeding classifications.
    European heart journal, 2010, Volume: 31, Issue:2

    Topics: Aged; Blood Coagulation Tests; Clopidogrel; Coronary Artery Disease; Female; Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Stroke; Ticlopidine

2010
Clopidogrel and calcium-channel blockers: a clinically important interaction?
    Heart (British Cardiac Society), 2010, Volume: 96, Issue:3

    Topics: Calcium Channel Blockers; Clopidogrel; Coronary Artery Disease; Drug Combinations; Drug Interactions; Humans; Platelet Aggregation Inhibitors; Ticlopidine

2010
Platelet-bound P-selectin expression in patients with coronary artery disease: impact on clinical presentation and myocardial necrosis, and effect of diabetes mellitus and anti-platelet medication.
    Journal of thrombosis and haemostasis : JTH, 2010, Volume: 8, Issue:1

    Topics: Acute Coronary Syndrome; Angina Pectoris; Aspirin; Biomarkers; Blood Platelets; Clopidogrel; Coronary Artery Disease; Creatine Kinase, MB Form; Diabetes Mellitus; Drug Therapy, Combination; Flow Cytometry; Humans; Myocardium; Necrosis; P-Selectin; Platelet Activation; Platelet Aggregation Inhibitors; Ticlopidine; Time Factors; Treatment Outcome; Troponin I; Up-Regulation

2010
Impact of P2Y12-ADP receptor polymorphism on the efficacy of clopidogrel dose-adjustment according to platelet reactivity monitoring in coronary artery disease patients.
    Thrombosis research, 2010, Volume: 125, Issue:4

    Topics: Aged; Alleles; Blood Platelets; Cell Adhesion Molecules; Clopidogrel; Coronary Artery Disease; Coronary Disease; Female; Genotype; Humans; Male; Microfilament Proteins; Middle Aged; Phosphoproteins; Polymorphism, Genetic; Prospective Studies; Receptors, Purinergic P2; Social Adjustment; Ticlopidine

2010
High residual platelet reactivity after clopidogrel loading and long-term clinical outcome after drug-eluting stenting for unprotected left main coronary disease.
    Circulation, 2009, Dec-01, Volume: 120, Issue:22

    Topics: Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Clopidogrel; Combined Modality Therapy; Coronary Artery Disease; Coronary Restenosis; Coronary Thrombosis; Death, Sudden, Cardiac; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Predictive Value of Tests; Risk Factors; Ticlopidine

2009
Relation of body mass index to high on-treatment platelet reactivity and of failed clopidogrel dose adjustment according to platelet reactivity monitoring in patients undergoing percutaneous coronary intervention.
    The American journal of cardiology, 2009, Dec-01, Volume: 104, Issue:11

    Topics: Aged; Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Body Mass Index; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Diabetes Complications; Dose-Response Relationship, Drug; Female; France; Genetic Markers; Genotype; Humans; Male; Middle Aged; Monitoring, Physiologic; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Predictive Value of Tests; Prospective Studies; Risk Factors; Ticlopidine

2009
Multiple electrode aggregometry predicts stent thrombosis better than the vasodilator-stimulated phosphoprotein phosphorylation assay.
    Journal of thrombosis and haemostasis : JTH, 2010, Volume: 8, Issue:2

    Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Biomarkers; Blood Platelets; Cell Adhesion Molecules; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Electrodes; Female; Humans; Logistic Models; Male; Microfilament Proteins; Middle Aged; Phosphoproteins; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Prospective Studies; ROC Curve; Sensitivity and Specificity; Stents; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome

2010
Antiplatelet effects of clopidogrel and bleeding in patients undergoing coronary stent placement.
    Journal of thrombosis and haemostasis : JTH, 2010, Volume: 8, Issue:2

    Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Drug-Eluting Stents; Female; Germany; Hemorrhage; Humans; Logistic Models; Male; Middle Aged; Odds Ratio; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Risk Assessment; Risk Factors; ROC Curve; Severity of Illness Index; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome

2010
There is no place like home after successful percutaneous coronary intervention.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2009, Dec-01, Volume: 74, Issue:7

    Topics: Abciximab; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Evidence-Based Medicine; Hemorrhage; Humans; Immunoglobulin Fab Fragments; Infusions, Parenteral; Injections; Length of Stay; Myocardial Infarction; Patient Discharge; Platelet Aggregation Inhibitors; Radial Artery; Risk Assessment; Risk Factors; Stents; Ticlopidine; Time Factors; Treatment Outcome

2009
Association of platelet responsiveness with clopidogrel metabolism: role of compliance in the assessment of "resistance".
    American heart journal, 2009, Volume: 158, Issue:6

    Topics: Aged; Blood Platelets; Brain Ischemia; Clopidogrel; Coronary Artery Disease; Drug Resistance; Female; Humans; Male; Middle Aged; Patient Compliance; Platelet Aggregation Inhibitors; Retrospective Studies; Stroke; Ticlopidine

2009
Aortic thromboembolism successfully treated with anticoagulation and antiplatelet therapy.
    The American journal of medicine, 2009, Volume: 122, Issue:12

    Topics: Anticoagulants; Aorta, Thoracic; Arm; Clopidogrel; Coronary Artery Disease; Echocardiography, Transesophageal; Humans; Ischemia; Male; Middle Aged; Platelet Aggregation Inhibitors; Thromboembolism; Ticlopidine; Warfarin

2009
Common variation in the platelet receptor P2RY12 gene is associated with residual on-clopidogrel platelet reactivity in patients undergoing elective percutaneous coronary interventions.
    Circulation. Cardiovascular genetics, 2009, Volume: 2, Issue:5

    Topics: Aged; Blood Platelets; Clopidogrel; Cohort Studies; Coronary Artery Disease; Genetic Variation; Humans; Intraoperative Complications; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Premedication; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Ticlopidine

2009
Which platelet function test is suitable to monitor clopidogrel responsiveness? A pharmacokinetic analysis on the active metabolite of clopidogrel.
    Journal of thrombosis and haemostasis : JTH, 2010, Volume: 8, Issue:3

    Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Biotransformation; Blood Platelets; Cell Adhesion Molecules; Chromatography, Liquid; Clopidogrel; Coronary Artery Disease; Drug Resistance; Female; Flow Cytometry; Humans; Linear Models; Male; Microfilament Proteins; Middle Aged; Phosphoproteins; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Tandem Mass Spectrometry; Ticlopidine

2010
Cytochrome 2C19*17 allelic variant, platelet aggregation, bleeding events, and stent thrombosis in clopidogrel-treated patients with coronary stent placement.
    Circulation, 2010, Feb-02, Volume: 121, Issue:4

    Topics: Aged; Aryl Hydrocarbon Hydroxylases; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Cytochrome P-450 CYP2C19; Female; Follow-Up Studies; Gene Frequency; Genotype; Hemorrhage; Heterozygote; Humans; Male; Middle Aged; Multivariate Analysis; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Risk Factors; Stents; Ticlopidine; Treatment Outcome

2010
Antiplatelet effect of 50-mg maintenance dose of clopidogrel compared to 200 mg ticlopidine: a preliminary study.
    Heart and vessels, 2010, Volume: 25, Issue:1

    Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Asian People; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Female; Humans; Japan; Male; Middle Aged; Pilot Projects; Platelet Aggregation; Platelet Aggregation Inhibitors; Stents; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome

2010
Highlights from Transcatheter Cardiovascular Therapeutics 2009: San Francisco, California, September 21 to 25, 2009.
    The Journal of thoracic and cardiovascular surgery, 2010, Volume: 139, Issue:2

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Cardiac Surgical Procedures; Clinical Trials as Topic; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Heart Valve Diseases; Humans; Myocardial Revascularization; Platelet Aggregation Inhibitors; Retreatment; Stents; Ticlopidine; Treatment Outcome

2010
Efficacy of modified dual antiplatelet therapy combined with warfarin following percutaneous coronary intervention with drug-eluting stents.
    The Journal of invasive cardiology, 2010, Volume: 22, Issue:2

    Topics: Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Combined Modality Therapy; Coronary Artery Disease; Coronary Restenosis; Coronary Thrombosis; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Retrospective Studies; Ticlopidine; Treatment Outcome; Warfarin

2010
Very late drug-eluting stent thrombosis in the perioperative period of endoscopic choledocholithotomy.
    Acta cardiologica, 2009, Volume: 64, Issue:6

    Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug-Eluting Stents; Endoscopy, Digestive System; Gallstones; Humans; Male; Middle Aged; Perioperative Care; Platelet Aggregation Inhibitors; Ticlopidine; Time Factors

2009
High residual platelet reactivity after clopidogrel: extent of coronary atherosclerosis and periprocedural myocardial infarction in patients with stable angina undergoing percutaneous coronary intervention.
    JACC. Cardiovascular interventions, 2010, Volume: 3, Issue:1

    Topics: Aged; Angina Pectoris; Angioplasty, Balloon, Coronary; Blood Platelets; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Drug Resistance; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Risk Assessment; Risk Factors; Severity of Illness Index; Stents; Ticlopidine; Treatment Outcome

2010
In vitro effects of recombinant activated factor VIIa (NovoSeven) on clopidogrel-induced platelet inhibition.
    Thrombosis and haemostasis, 2010, Volume: 103, Issue:4

    Topics: Adenosine Diphosphate; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Clopidogrel; Coagulants; Collagen; Coronary Artery Disease; Factor VIIa; Female; Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Recombinant Proteins; Thrombin; Ticlopidine; Time Factors; Treatment Outcome

2010
Triple therapy: the future or from the past?
    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2010, Volume: 5, Issue:6

    Topics: Administration, Oral; Anticoagulants; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Humans; Myocardial Revascularization; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Prognosis; Risk Factors; Stents; Thromboembolism; Ticlopidine

2010
Safety of drug eluting stents in patients on chronic anticoagulation using long-term single antiplatelet treatment with clopidogrel.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2010, May-01, Volume: 75, Issue:6

    Topics: Aged; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Multivariate Analysis; Platelet Aggregation Inhibitors; Ticlopidine

2010
Triple therapy: triple safety or triple danger?
    The American journal of cardiology, 2010, Feb-15, Volume: 105, Issue:4

    Topics: Administration, Oral; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Drug Tolerance; Evidence-Based Medicine; Humans; Platelet Aggregation Inhibitors; Risk Assessment; Stents; Thromboembolism; Ticlopidine; Treatment Outcome

2010
Oral anticoagulation with coumarin derivatives and antiplatelet effects of clopidogrel.
    European heart journal, 2010, Volume: 31, Issue:10

    Topics: Adenosine Diphosphate; Administration, Oral; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Coronary Artery Disease; Cross-Sectional Studies; Drug Interactions; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Multivariate Analysis; Phenprocoumon; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine

2010
Impact of high-responsiveness to dual antiplatelet therapy on bleeding complications in patients receiving drug-eluting stents.
    Circulation journal : official journal of the Japanese Circulation Society, 2010, Volume: 74, Issue:4

    Topics: Aged; Angioplasty, Balloon, Laser-Assisted; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Drug-Eluting Stents; Female; Follow-Up Studies; Hemorrhage; Humans; Male; Middle Aged; Myocardial Ischemia; Platelet Aggregation Inhibitors; Pyridines; Retrospective Studies; Risk Factors; Ticlopidine; Treatment Outcome

2010
Role of ticagrelor in clopidogrel nonresponders: resistance is futile?
    Circulation, 2010, Mar-16, Volume: 121, Issue:10

    Topics: Adenosine; Clopidogrel; Coronary Artery Disease; Drug Resistance; Humans; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2Y12; Thiophenes; Ticagrelor; Ticlopidine

2010
Evaluation of antiplatelet effects of a modified protocol by platelet aggregation in patients undergoing "one-stop" hybrid coronary revascularization.
    Platelets, 2010, Volume: 21, Issue:3

    Topics: Adenosine Diphosphate; Angioplasty, Balloon, Coronary; Arachidonic Acid; Aspirin; Clopidogrel; Combined Modality Therapy; Coronary Artery Bypass; Coronary Artery Disease; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Prospective Studies; Ticlopidine

2010
Comparison of different antithrombotic regimens for patients with atrial fibrillation undergoing drug-eluting stent implantation.
    Circulation journal : official journal of the Japanese Circulation Society, 2010, Volume: 74, Issue:4

    Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Atrial Fibrillation; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Drug-Eluting Stents; Female; Fibrinolytic Agents; Follow-Up Studies; Hemorrhage; Humans; Kaplan-Meier Estimate; Male; Prospective Studies; Risk Factors; Stroke; Thromboembolism; Ticlopidine; Treatment Outcome; Warfarin

2010
Impact of chronic kidney disease on platelet function profiles in diabetes mellitus patients with coronary artery disease taking dual antiplatelet therapy.
    Journal of the American College of Cardiology, 2010, Mar-16, Volume: 55, Issue:11

    Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Cross-Sectional Studies; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Nephropathies; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine; Treatment Outcome

2010
Point-of-care assessment of platelet reactivity after clopidogrel to predict myonecrosis in patients undergoing percutaneous coronary intervention.
    JACC. Cardiovascular interventions, 2010, Volume: 3, Issue:3

    Topics: Aged; Angioplasty, Balloon, Coronary; Biomarkers; Blood Platelets; Clopidogrel; Coronary Artery Disease; Creatine Kinase, MB Form; Female; Humans; Logistic Models; Male; Middle Aged; Myocardial Infarction; Myocardium; Necrosis; Odds Ratio; Platelet Aggregation Inhibitors; Platelet Function Tests; Point-of-Care Systems; Predictive Value of Tests; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Risk Assessment; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome; Troponin I

2010
Platelet inhibition with cangrelor.
    The New England journal of medicine, 2010, Mar-18, Volume: 362, Issue:11

    Topics: Adenosine Monophosphate; Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Artery Disease; Humans; Platelet Aggregation Inhibitors; Research Design; Ticlopidine

2010
A comparison of the VerifyNow P2Y12 point-of-care device and light transmission aggregometry to monitor platelet function with prasugrel and clopidogrel: an integrated analysis.
    Journal of cardiovascular pharmacology, 2010, Volume: 56, Issue:1

    Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Adult; Aged; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Databases, Factual; Dose-Response Relationship, Drug; Drug Monitoring; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Piperazines; Platelet Aggregation Inhibitors; Platelet Function Tests; Point-of-Care Systems; Prasugrel Hydrochloride; Thiophenes; Ticlopidine

2010
Plasma sequestration: a good therapy to prevent the deleterious effect of clopidogrel when clopidogrel is used within one to four days of coronary bypass surgery.
    Perfusion, 2010, Volume: 25, Issue:2

    Topics: Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Critical Care; Erythrocyte Transfusion; Humans; Length of Stay; Plasmapheresis; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Preoperative Care; Ticlopidine; Time Factors

2010
Antithrombotic management in patients undergoing coronary stent implantation requiring chronic oral anticoagulation: how to balance safety and efficacy?
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2010, May-01, Volume: 75, Issue:6

    Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Drug-Eluting Stents; Humans; Platelet Aggregation Inhibitors; Ticlopidine

2010
Incidence, correlates, and clinical impact of nuisance bleeding after antiplatelet therapy for patients with drug-eluting stents.
    American heart journal, 2010, Volume: 159, Issue:5

    Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Drug-Eluting Stents; Female; Hemorrhage; Humans; Male; Middle Aged; Multivariate Analysis; Platelet Aggregation Inhibitors; Ticlopidine

2010
Dual low response to acetylsalicylic acid and clopidogrel is associated with myonecrosis and stent thrombosis after coronary stent implantation.
    American heart journal, 2010, Volume: 159, Issue:5

    Topics: Acute Coronary Syndrome; Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Multivariate Analysis; Myocardium; Platelet Aggregation Inhibitors; Stents; Ticlopidine

2010
Rotablation in the drug eluting era: immediate and long-term results from a single center experience.
    Journal of interventional cardiology, 2010, Volume: 23, Issue:3

    Topics: Aged; Angioplasty, Balloon, Coronary; Angioplasty, Balloon, Laser-Assisted; Aspirin; Atherectomy, Coronary; Clopidogrel; Coronary Artery Disease; Drug-Eluting Stents; Female; Humans; Male; Platelet Aggregation Inhibitors; Retrospective Studies; Ticlopidine; Time Factors; Treatment Outcome

2010
Potentiation of clopidogrel active metabolite formation by rifampicin leads to greater P2Y12 receptor blockade and inhibition of platelet aggregation after clopidogrel.
    Journal of thrombosis and haemostasis : JTH, 2010, Volume: 8, Issue:8

    Topics: Adenosine Diphosphate; Adult; Area Under Curve; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug Administration Schedule; Drug Synergism; Humans; Male; Middle Aged; Platelet Aggregation; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Rifampin; Ticlopidine

2010
Carotid angioplasty in asymptomatic patients undergoing CABG surgery.
    International angiology : a journal of the International Union of Angiology, 2010, Volume: 29, Issue:3

    Topics: Aged; Angioplasty, Balloon; Anticoagulants; Carotid Stenosis; Clopidogrel; Coronary Angiography; Coronary Artery Bypass; Coronary Artery Disease; Endarterectomy, Carotid; Feasibility Studies; Female; Heparin; Humans; Ischemic Attack, Transient; Male; Middle Aged; Platelet Aggregation Inhibitors; Severity of Illness Index; Stents; Stroke; Ticlopidine; Time Factors; Treatment Outcome; Ultrasonography, Doppler

2010
Effect of 450-mg loading dose of clopidogrel on platelet function in Japanese patients undergoing coronary stent placement.
    Heart and vessels, 2010, Volume: 25, Issue:3

    Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Asian People; Clopidogrel; Coronary Artery Disease; Female; Hemorrhage; Humans; Japan; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Time Factors; Treatment Outcome

2010
Impact of inflammatory state and metabolic control on responsiveness to dual antiplatelet therapy in type 2 diabetics after PCI: prognostic relevance of residual platelet aggregability in diabetics undergoing coronary interventions.
    Clinical research in cardiology : official journal of the German Cardiac Society, 2010, Volume: 99, Issue:11

    Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Biomarkers; Blood Glucose; C-Reactive Protein; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Cytokines; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Immunoassay; Inflammation; Male; Pilot Projects; Platelet Aggregation Inhibitors; Retrospective Studies; Ticlopidine; Treatment Outcome

2010
Efficiency of preoperative tranexamic Acid in coronary bypass surgery: an analysis correlated with preoperative clopidogrel use.
    The heart surgery forum, 2010, Volume: 13, Issue:3

    Topics: Aged; Antifibrinolytic Agents; Blood Transfusion; Clopidogrel; Confidence Intervals; Coronary Artery Bypass; Coronary Artery Disease; Female; Health Status Indicators; Humans; Length of Stay; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Patient Readmission; Platelet Aggregation Inhibitors; Postoperative Hemorrhage; Preanesthetic Medication; Prospective Studies; Regression Analysis; Risk Factors; Statistics as Topic; Ticlopidine; Tranexamic Acid; Turkey

2010
Risk of adverse outcomes in Taiwan associated with concomitant use of clopidogrel and proton pump inhibitors in patients who received percutaneous coronary intervention.
    The American journal of cardiology, 2010, Jun-15, Volume: 105, Issue:12

    Topics: Aged; Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Patient Readmission; Population Surveillance; Prognosis; Proton Pump Inhibitors; Retrospective Studies; Risk Factors; Survival Rate; Taiwan; Ticlopidine

2010
The H(2)-receptor antagonist ranitidine interferes with clopidogrel-mediated P2Y(12) inhibition in platelets.
    Pharmacological research, 2010, Volume: 62, Issue:4

    Topics: Aged; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug Interactions; Female; Histamine H2 Antagonists; Humans; Male; Middle Aged; Platelet Activation; Purinergic P2Y Receptor Antagonists; Ranitidine; Receptors, Purinergic P2Y12; Ticlopidine

2010
In-laboratory high-dose clopidogrel loading: do we need a mirror of diamond for "Armida's garden"?
    Journal of the American College of Cardiology, 2010, Aug-10, Volume: 56, Issue:7

    Topics: Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Artery Disease; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome

2010
Impact of inflammatory markers on platelet inhibition and cardiovascular outcome including stent thrombosis in patients with symptomatic coronary artery disease.
    Atherosclerosis, 2010, Volume: 213, Issue:1

    Topics: Acute Coronary Syndrome; Aged; Angioplasty, Balloon; Aspirin; Blood Platelets; C-Reactive Protein; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Female; Humans; Inflammation; Male; Pilot Projects; Platelet Activation; Stents; Ticlopidine; Treatment Outcome

2010
Does black ethnicity influence the development of stent thrombosis in the drug-eluting stent era?
    Circulation, 2010, Sep-14, Volume: 122, Issue:11

    Topics: Aged; Black People; Clopidogrel; Coronary Artery Disease; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Patient Compliance; Platelet Aggregation Inhibitors; Regression Analysis; Retrospective Studies; Risk Factors; Social Class; Thrombosis; Ticlopidine; Treatment Outcome; White People

2010
Consensus and future directions on the definition of high on-treatment platelet reactivity to adenosine diphosphate.
    Journal of the American College of Cardiology, 2010, Sep-14, Volume: 56, Issue:12

    Topics: Adenosine Diphosphate; Angioplasty, Balloon, Coronary; Blood Platelets; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug Resistance; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Platelet Function Tests; Purinergic P2 Receptor Antagonists; Risk Factors; ROC Curve; Stents; Ticlopidine

2010
The new INNOVANCE® PFA P2Y cartridge is sensitive to the detection of the P2Y₁₂ receptor inhibition.
    Platelets, 2011, Volume: 22, Issue:1

    Topics: Adenosine Monophosphate; Adult; Aged; Aged, 80 and over; Biological Assay; Biomarkers; Blood Platelets; Case-Control Studies; Cell Adhesion Molecules; Clopidogrel; Coronary Artery Disease; Female; Flow Cytometry; Humans; Male; Microfilament Proteins; Middle Aged; Phosphoproteins; Phosphorylation; Platelet Aggregation Inhibitors; Predictive Value of Tests; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Sensitivity and Specificity; Ticlopidine; Young Adult

2011
Use of genetics and transcriptomics in the diagnosis and treatment of coronary artery disease.
    Revista espanola de cardiologia, 2010, Volume: 63, Issue:10

    Topics: Anticoagulants; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Gene Expression Profiling; Genetic Testing; Humans; Platelet Aggregation Inhibitors; Ticlopidine; Warfarin

2010
Intracoronary shear-related up-regulation of platelet P-selectin and platelet-monocyte aggregation despite the use of aspirin and clopidogrel.
    Blood, 2011, Jan-06, Volume: 117, Issue:1

    Topics: Aged; Aspirin; Blood Platelets; CD11b Antigen; Clopidogrel; Coronary Artery Disease; Coronary Stenosis; Flow Cytometry; Humans; Leukocytes; Monocytes; P-Selectin; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine; Up-Regulation

2011
Determination of the prevalence of aspirin and clopidogrel resistances in patients with coronary artery disease by using various platelet-function tests.
    The Korean journal of laboratory medicine, 2010, Volume: 30, Issue:5

    Topics: Aged; Aspirin; Cilostazol; Clopidogrel; Coronary Artery Disease; Drug Resistance; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Tetrazoles; Ticlopidine

2010
Letter by Lozano et al regarding article, "Increased risk of bleeding in patients on clopidogrel therapy after drug-eluting stents implantation: insights from the HMO Research Network-Stent Registry (HMORN-stent)".
    Circulation. Cardiovascular interventions, 2010, Volume: 3, Issue:5

    Topics: Clopidogrel; Coronary Artery Disease; Drug-Eluting Stents; Humans; Myocardial Infarction; Postoperative Hemorrhage; Prosthesis Implantation; Risk Factors; Survival Analysis; Ticlopidine; Withholding Treatment

2010
Pilot study of the antiplatelet effect of increased clopidogrel maintenance dosing and its relationship to CYP2C19 genotype in patients with high on-treatment reactivity.
    JACC. Cardiovascular interventions, 2010, Volume: 3, Issue:10

    Topics: Aged; Aryl Hydrocarbon Hydroxylases; Body Mass Index; California; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Female; Genotype; Humans; Logistic Models; Longitudinal Studies; Male; Middle Aged; Phenotype; Pilot Projects; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Polymorphism, Genetic; Predictive Value of Tests; Receptors, Purinergic P2Y12; Risk Assessment; Risk Factors; Ticlopidine

2010
Acceptance of high platelet reactivity as a risk factor: now, what do we do about it?
    JACC. Cardiovascular interventions, 2010, Volume: 3, Issue:10

    Topics: Aryl Hydrocarbon Hydroxylases; Body Mass Index; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Genotype; Humans; Phenotype; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Polymorphism, Genetic; Predictive Value of Tests; Receptors, Purinergic P2Y12; Risk Assessment; Risk Factors; Ticlopidine

2010
Interaction of clopidogrel and omeprazole.
    The New England journal of medicine, 2010, Nov-11, Volume: 363, Issue:20

    Topics: Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Drug Interactions; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Humans; Omeprazole; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Ticlopidine

2010
The cytochrome 2C19*2 and *3 alleles attenuate response to clopidogrel similarly in East Asian patients undergoing elective percutaneous coronary intervention.
    Thrombosis research, 2011, Volume: 127, Issue:1

    Topics: Adenosine Diphosphate; Aged; Analysis of Variance; Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Asian People; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Female; Gene Frequency; Genotype; Humans; Male; Middle Aged; Phenotype; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Republic of Korea; Risk Assessment; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome

2011
Hybrid revascularization, comprising coronary artery bypass graft with exclusive arterial conduits followed by early drug-eluting stent implantation, in multivessel coronary artery disease.
    Archives of cardiovascular diseases, 2010, Volume: 103, Issue:10

    Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Case-Control Studies; Chi-Square Distribution; Clopidogrel; Combined Modality Therapy; Coronary Artery Bypass; Coronary Artery Bypass, Off-Pump; Coronary Artery Disease; Drug-Eluting Stents; Feasibility Studies; Female; France; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Prospective Studies; Risk Assessment; Risk Factors; Ticlopidine; Time Factors; Treatment Outcome

2010
Impact of CYP2C19 polymorphism and smoking on response to clopidogrel in patients with stable coronary artery disease.
    Chinese medical journal, 2010, Volume: 123, Issue:22

    Topics: Aged; Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Ticlopidine

2010
Concomitant use of proton pump inhibitors and clopidogrel in patients with coronary, cerebrovascular, or peripheral artery disease in the factores de Riesgo y ENfermedad Arterial (FRENA) registry.
    Journal of cardiovascular pharmacology, 2011, Volume: 57, Issue:1

    Topics: Aged; Cerebrovascular Disorders; Clopidogrel; Contraindications; Coronary Artery Disease; Drug Interactions; Female; Humans; Male; Middle Aged; Myocardial Infarction; Peripheral Arterial Disease; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Registries; Retrospective Studies; Stroke; Ticlopidine

2011
Differential impacts of CYP2C19 gene polymorphisms on the antiplatelet effects of clopidogrel and ticlopidine.
    Clinical pharmacology and therapeutics, 2011, Volume: 89, Issue:2

    Topics: Aged; Aryl Hydrocarbon Hydroxylases; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Ticlopidine

2011
Measurement of platelet reactivity of patients with cardiovascular disease on-treatment with acetyl salicylic acid: a prospective study.
    Heart and vessels, 2011, Volume: 26, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Aspirin; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Drug Resistance; Drug Therapy, Combination; Female; Humans; Logistic Models; Male; Medication Adherence; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Risk Assessment; Risk Factors; Sex Factors; Ticlopidine; Treatment Outcome

2011
An early and simple predictor of severe left main and/or three-vessel disease in patients with non-ST-segment elevation acute coronary syndrome.
    The American journal of cardiology, 2011, Feb-15, Volume: 107, Issue:4

    Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Biomarkers; Clopidogrel; Coronary Angiography; Coronary Artery Bypass; Coronary Artery Disease; Early Diagnosis; Electrocardiography; Female; Heart Conduction System; Humans; Male; Middle Aged; Multivariate Analysis; Platelet Aggregation Inhibitors; Predictive Value of Tests; Prognosis; Retrospective Studies; Risk Assessment; Sensitivity and Specificity; Severity of Illness Index; Ticlopidine; Treatment Outcome; Troponin T

2011
Frequency and location of yellow and disrupted coronary plaques in patients as detected by angioscopy.
    Circulation journal : official journal of the Japanese Circulation Society, 2011, Volume: 75, Issue:3

    Topics: Acute Coronary Syndrome; Aged; Angioscopy; Aspirin; Clopidogrel; Coronary Artery Disease; Disease Progression; Female; Humans; Incidence; Male; Middle Aged; Myocardial Infarction; Plaque, Atherosclerotic; Platelet Aggregation Inhibitors; Retrospective Studies; Severity of Illness Index; Ticlopidine

2011
Light transmittance aggregometry induced by different concentrations of adenosine diphosphate to monitor clopidogrel therapy: a methodological study.
    Therapeutic drug monitoring, 2011, Volume: 33, Issue:1

    Topics: Adenosine Diphosphate; Angioplasty; Clopidogrel; Coronary Artery Disease; Drug Monitoring; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Platelet Function Tests; Point-of-Care Systems; Ticlopidine

2011
Functional profile of the platelet P2Y₁₂ receptor signalling pathway in patients with type 2 diabetes mellitus and coronary artery disease.
    Thrombosis and haemostasis, 2011, Volume: 105, Issue:4

    Topics: Aged; Blood Platelets; Cell Adhesion Molecules; Clopidogrel; Coronary Artery Disease; Diabetes Mellitus, Type 2; Female; Humans; Male; Microfilament Proteins; Middle Aged; Phosphoproteins; Phosphorylation; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Signal Transduction; Thrombosis; Ticlopidine

2011
Clinical follow-up 3 years after everolimus- and paclitaxel-eluting stents: a pooled analysis from the SPIRIT II (A Clinical Evaluation of the XIENCE V Everolimus Eluting Coronary Stent System in the Treatment of Patients With De Novo Native Coronary Arte
    JACC. Cardiovascular interventions, 2010, Volume: 3, Issue:12

    Topics: Angioplasty, Balloon, Coronary; Antineoplastic Agents, Phytogenic; Aspirin; Clopidogrel; Confidence Intervals; Coronary Artery Disease; Drug-Eluting Stents; Everolimus; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Kaplan-Meier Estimate; Logistic Models; Male; Middle Aged; Paclitaxel; Platelet Aggregation Inhibitors; Proportional Hazards Models; Randomized Controlled Trials as Topic; Risk; Risk Reduction Behavior; Sirolimus; Ticlopidine; Time Factors

2010
Invited commentary.
    The Annals of thoracic surgery, 2011, Volume: 91, Issue:2

    Topics: Clopidogrel; Coronary Artery Bypass, Off-Pump; Coronary Artery Disease; Drainage; Humans; Intubation, Gastrointestinal; Minimally Invasive Surgical Procedures; Platelet Aggregation Inhibitors; Postoperative Complications; Premedication; Sternotomy; Thrombosis; Ticlopidine

2011
Low responsiveness to clopidogrel increases risk among CKD patients undergoing coronary intervention.
    Journal of the American Society of Nephrology : JASN, 2011, Volume: 22, Issue:4

    Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Chronic Disease; Clopidogrel; Cohort Studies; Coronary Artery Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Hemorrhage; Humans; Kidney Diseases; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Risk Factors; Ticlopidine; Treatment Outcome

2011
Relationship between peripheral arterial reactive hyperemia and residual platelet reactivity after 600 mg clopidogrel.
    Journal of thrombosis and thrombolysis, 2011, Volume: 32, Issue:1

    Topics: Acute Coronary Syndrome; Aged; Clopidogrel; Coronary Artery Disease; Endothelium, Vascular; Female; Humans; Hyperemia; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine; Time Factors

2011
[Relationships of blood stasis syndrome, CYP2C19 gene polymorphism with clopidogrel resistance and post-PCI prognosis].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2010, Volume: 30, Issue:12

    Topics: Aged; Aryl Hydrocarbon Hydroxylases; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Diagnosis, Differential; Drug Resistance; Female; Humans; Male; Medicine, Chinese Traditional; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Prognosis; Ticlopidine

2010
Clopidogrel with or without omeprazole in coronary disease.
    The New England journal of medicine, 2011, 02-17, Volume: 364, Issue:7

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Cardiovascular Diseases; Chemistry, Pharmaceutical; Clopidogrel; Coronary Artery Disease; Drug Interactions; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Humans; Omeprazole; Pantoprazole; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Ticlopidine

2011
Clopidogrel with or without omeprazole in coronary disease.
    The New England journal of medicine, 2011, 02-17, Volume: 364, Issue:7

    Topics: Clopidogrel; Coronary Artery Disease; Cost-Benefit Analysis; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Humans; Omeprazole; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Ticlopidine

2011
Safety of clopidogrel and proton pump inhibitors in patients undergoing drug-eluting stent implantation.
    Coronary artery disease, 2011, Volume: 22, Issue:3

    Topics: Acute Coronary Syndrome; Aged; Blood Vessel Prosthesis Implantation; Clopidogrel; Cohort Studies; Combined Modality Therapy; Coronary Artery Disease; Drug Interactions; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Retrospective Studies; Ticlopidine

2011
[Assessing clinical efficacy of the generic clopidogrel "Egutromb" in roentgenosurgical practice].
    Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery, 2010, Volume: 16, Issue:4

    Topics: Clopidogrel; Coronary Angiography; Coronary Artery Bypass; Coronary Artery Disease; Dose-Response Relationship, Drug; Drugs, Generic; Humans; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome

2010
Oral antiplatelet therapy for atherothrombotic disease: current evidence and new directions.
    American heart journal, 2011, Volume: 161, Issue:3

    Topics: Acute Coronary Syndrome; Adenosine; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug Therapy, Combination; Humans; Lactones; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Pyridines; Quinazolinones; Randomized Controlled Trials as Topic; Receptor, PAR-1; Sulfonamides; Ticagrelor; Ticlopidine

2011
The relation between CYP2C19 genotype and phenotype in stented patients on maintenance dual antiplatelet therapy.
    American heart journal, 2011, Volume: 161, Issue:3

    Topics: Aged; Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Female; Genotype; Humans; Linkage Disequilibrium; Male; Middle Aged; Phenotype; Platelet Aggregation; Platelet Aggregation Inhibitors; Stents; Ticlopidine

2011
Lack of impact of calcium-channel blockers on the pharmacodynamic effect and the clinical efficacy of clopidogrel after drug-eluting stenting.
    American heart journal, 2011, Volume: 161, Issue:3

    Topics: Aged; Calcium Channel Blockers; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Coronary Thrombosis; Drug Synergism; Drug-Eluting Stents; Endpoint Determination; Female; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine

2011
Impact of combination of calcium-channel blockers with clopidogrel on clinical outcomes in patients with coronary artery disease.
    International journal of cardiology, 2011, Jun-02, Volume: 149, Issue:2

    Topics: Aged; Calcium Channel Blockers; Clopidogrel; Cohort Studies; Coronary Artery Disease; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Ticlopidine; Treatment Outcome

2011
Peri-operative management of antiplatelet therapy in patients with coronary artery disease: joint position paper by members of the working group on Perioperative Haemostasis of the Society on Thrombosis and Haemostasis Research (GTH), the working group on
    Thrombosis and haemostasis, 2011, Volume: 105, Issue:5

    Topics: Aspirin; Blood Loss, Surgical; Cardiovascular Surgical Procedures; Clopidogrel; Contraindications; Coronary Artery Disease; Drug-Eluting Stents; Evidence-Based Medicine; Hemostasis, Surgical; Humans; Perioperative Care; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Precision Medicine; Ticlopidine

2011
A case of subacute thrombosis associated with clopidogrel resistance after implantation of a zotarolimus-eluting stent.
    Heart and vessels, 2012, Volume: 27, Issue:1

    Topics: Aged; Angioplasty, Balloon, Coronary; Anterior Wall Myocardial Infarction; Aryl Hydrocarbon Hydroxylases; Aspirin; Cardiovascular Agents; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Drug Resistance; Drug-Eluting Stents; Female; Genotype; Humans; Phenotype; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Prosthesis Design; Sirolimus; Thrombectomy; Thrombosis; Ticlopidine; Treatment Outcome; Ultrasonography, Interventional

2012
Intra-individual variability of residual platelet reactivity assessed by the VerifyNow-P2Y12 assay in patients with clopidogrel resistance after percutaneous coronary intervention.
    Platelets, 2011, Volume: 22, Issue:4

    Topics: Aged; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug Resistance; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Function Tests; Purinergic P2Y Receptor Antagonists; Ticlopidine

2011
Left main stent thrombosis complicated by eptifibatide-induced acute thrombocytopenia.
    Texas Heart Institute journal, 2011, Volume: 38, Issue:2

    Topics: Acute Disease; Angioplasty, Balloon, Coronary; Aspirin; Cardiac Catheterization; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Drug Therapy, Combination; Electrocardiography; Eptifibatide; Heparin; Humans; Male; Middle Aged; Peptides; Platelet Aggregation Inhibitors; Platelet Count; Stents; Thrombectomy; Thrombocytopenia; Thrombosis; Ticlopidine; Treatment Outcome

2011
Impaired inhibition of P2Y(12) by clopidogrel is a major determinant of cardiac death in diabetes mellitus patients treated by percutaneous coronary intervention.
    Atherosclerosis, 2011, Volume: 217, Issue:2

    Topics: Aged; Angioplasty, Balloon, Coronary; Cell Adhesion Molecules; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Diabetes Mellitus, Type 2; Drug Resistance; Female; Flow Cytometry; France; Heart Diseases; Humans; Kaplan-Meier Estimate; Male; Microfilament Proteins; Middle Aged; Myocardial Infarction; Phosphoproteins; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Proportional Hazards Models; Prospective Studies; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Registries; Risk Assessment; Risk Factors; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome

2011
Simultaneous drug-eluting and bare-metal stent implantation: long-term clinical outcome and findings of clinically indicated coronary angiography.
    Clinical cardiology, 2011, Volume: 34, Issue:5

    Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Confidence Intervals; Coronary Angiography; Coronary Artery Disease; Coronary Restenosis; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Multivariate Analysis; Paclitaxel; Platelet Aggregation Inhibitors; Prospective Studies; Statistics as Topic; Ticlopidine; Time Factors; Treatment Outcome

2011
Feasibility and safety of 7-Fr radial approach for complex PCI.
    Journal of interventional cardiology, 2011, Volume: 24, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Stenosis; Feasibility Studies; Female; Femoral Artery; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Radial Artery; Retrospective Studies; Ticlopidine; Ultrasonography, Interventional

2011
High on treatment platelet reactivity and stent thrombosis.
    Heart, lung & circulation, 2011, Volume: 20, Issue:8

    Topics: Adult; Aged; Angioplasty; Aspirin; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Stents; Thrombosis; Ticlopidine

2011
Percutaneous coronary intervention of unprotected left main coronary artery disease as culprit lesion in patients with acute myocardial infarction.
    JACC. Cardiovascular interventions, 2011, Volume: 4, Issue:6

    Topics: Aged; Angioplasty; Bundle-Branch Block; Clopidogrel; Confidence Intervals; Coronary Artery Disease; Coronary Vessels; Emergency Medical Services; Female; Health Status Indicators; Hemodynamics; Hospital Mortality; Humans; Italy; Logistic Models; Male; Myocardial Infarction; Odds Ratio; Platelet Aggregation Inhibitors; Prognosis; Retrospective Studies; Shock, Cardiogenic; Ticlopidine; Treatment Outcome

2011
A complex case of angulated and bifurcated lesion facilitated by excimer laser coronary angioplasty.
    Journal of interventional cardiology, 2011, Volume: 24, Issue:6

    Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Stenosis; Humans; Lasers, Excimer; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Ticlopidine

2011
Subacute stent thrombosis owing to complete clopidogrel resistance successfully managed with prasugrel.
    The Journal of invasive cardiology, 2011, Volume: 23, Issue:7

    Topics: Angioplasty, Balloon, Coronary; Anterior Wall Myocardial Infarction; Clopidogrel; Contraindications; Coronary Artery Disease; Drug Resistance; Drug-Eluting Stents; Humans; Male; Middle Aged; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Receptors, Purinergic P2Y12; Thiophenes; Thrombosis; Ticlopidine; Treatment Failure; Treatment Outcome

2011
Reduced antiplatelet therapy after drug-eluting stenting: multicenter Janus Flex carbostent implantation with short dual antiplatelet treatment for 2 or 6 months-MATRIX study.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2012, Sep-01, Volume: 80, Issue:3

    Topics: Aged; Aspirin; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Female; Hospitals, High-Volume; Humans; Italy; Kaplan-Meier Estimate; Logistic Models; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Proportional Hazards Models; Prospective Studies; Prosthesis Design; Registries; Risk Assessment; Risk Factors; Tacrolimus; Ticlopidine; Time Factors; Treatment Outcome

2012
Ability of the INNOVANCE PFA P2Y system to detect clopidogrel-induced ADP receptor blockade in preangiocath individuals.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2011, Volume: 22, Issue:7

    Topics: Adult; Angiography; Blood Coagulation; Blood Platelets; Clopidogrel; Coronary Artery Disease; Diagnostic Equipment; Drug Monitoring; Female; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Sensitivity and Specificity; Ticlopidine; Young Adult

2011
Letter by Gasparovic et al regarding article, "Aspirin plus clopidogrel versus aspirin alone after coronary artery bypass grafting: the clopidogrel after surgery for coronary artery disease (CASCADE) trial".
    Circulation, 2011, Aug-09, Volume: 124, Issue:6

    Topics: Aspirin; Clopidogrel; Combined Modality Therapy; Coronary Artery Bypass; Coronary Artery Disease; Drug Resistance; Follow-Up Studies; Graft Occlusion, Vascular; Hemorheology; Humans; Hyperplasia; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Saphenous Vein; Ticlopidine; Tunica Intima

2011
Letter by Bisdas et al regarding article, "Aspirin plus clopidogrel versus aspirin alone after coronary artery bypass grafting: the clopidogrel after surgery for coronary artery disease (CASCADE) trial".
    Circulation, 2011, Aug-09, Volume: 124, Issue:6

    Topics: Aspirin; Biotransformation; Clopidogrel; Combined Modality Therapy; Coronary Artery Bypass; Coronary Artery Disease; Cytochrome P-450 Enzyme System; Drug Interactions; Drug Resistance; Follow-Up Studies; Graft Occlusion, Vascular; Humans; Hyperplasia; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Saphenous Vein; Ticlopidine; Tunica Intima

2011
Effect of chronic kidney disease on platelet reactivity to dual-antiplatelet therapy in patients treated with drug-eluting stents.
    Heart and vessels, 2012, Volume: 27, Issue:5

    Topics: Aged; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Drug-Eluting Stents; Follow-Up Studies; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Renal Insufficiency, Chronic; Retrospective Studies; Ticlopidine

2012
Stent-related cardiac events beyond three years after implantation of the sirolimus-eluting stent (from the EVASTENT Patients).
    The American journal of cardiology, 2011, Nov-15, Volume: 108, Issue:10

    Topics: Clopidogrel; Cohort Studies; Coronary Artery Disease; Coronary Thrombosis; Diabetes Mellitus; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Male; Matched-Pair Analysis; Middle Aged; Myocardial Revascularization; Platelet Aggregation Inhibitors; Registries; Sirolimus; Ticlopidine

2011
Determination of cut-off levels for on-clopidogrel platelet aggregation based on functional CYP2C19 gene variants in patients undergoing elective percutaneous coronary intervention.
    Thrombosis research, 2011, Volume: 128, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Aspirin; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Female; Genotype; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Ticlopidine; Treatment Outcome

2011
Time dependence of clopidogrel loading effect: platelet activation versus platelet aggregation.
    Thrombosis research, 2012, Volume: 129, Issue:1

    Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Annexin A5; Aspirin; Baltimore; Clopidogrel; Collagen; Coronary Artery Disease; Drug Resistance; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Stents; Ticlopidine; Time Factors; Treatment Outcome

2012
Comparison of venous and arterial blood sampling for the assessment of platelet aggregation with whole blood impedance aggregometry.
    Scandinavian journal of clinical and laboratory investigation, 2011, Volume: 71, Issue:8

    Topics: Adenosine Diphosphate; Arachidonic Acid; Area Under Curve; Arteries; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Electric Impedance; Female; Humans; Male; Phlebotomy; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Research Design; Specimen Handling; Ticlopidine; Veins

2011
[Comparison of efficacy and safety of treatment with drugs of clopidogrel in patients after coronary artery stenting].
    Kardiologiia, 2011, Volume: 51, Issue:7

    Topics: Abdominal Pain; Aged; Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Coronary Vessels; Drug Substitution; Drugs, Generic; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Risk Factors; Stents; Therapeutic Equivalency; Ticlopidine; Treatment Outcome

2011
Optical coherence tomography findings during "evolving" stent thrombosis.
    The Journal of invasive cardiology, 2011, Volume: 23, Issue:9

    Topics: Abciximab; Antibodies, Monoclonal; Anticoagulants; Aspirin; Cardiopulmonary Resuscitation; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Coronary Vessels; Humans; Immunoglobulin Fab Fragments; Male; Middle Aged; Platelet Aggregation Inhibitors; Risk Factors; Stents; Ticlopidine; Tomography, Optical Coherence; Ultrasonography, Interventional

2011
Impact of gastric acid-suppressing therapies on platelet reactivity in patients with coronary artery disease treated with clopidogrel: results of a pharmacodynamic study.
    Journal of the American College of Cardiology, 2011, Sep-20, Volume: 58, Issue:13

    Topics: Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Platelet Activation; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Randomized Controlled Trials as Topic; Ticlopidine; Treatment Outcome

2011
The effect of clopidogrel besylate and clopidogrel hydrogensulfate on platelet aggregation in patients with coronary artery disease: a retrospective study.
    Thrombosis research, 2012, Volume: 129, Issue:6

    Topics: Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Retrospective Studies; Ticlopidine

2012
Effects of P2Y(1) receptor antagonism on the reactivity of platelets from patients with stable coronary artery disease using aspirin and clopidogrel.
    British journal of pharmacology, 2012, Volume: 166, Issue:1

    Topics: Adenosine Diphosphate; Aged; Aspirin; Blood Platelets; Clopidogrel; Collagen; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y1; Receptors, Thrombin; Thrombosis; Ticlopidine

2012
Clinical, angiographic, and genetic factors associated with early coronary stent thrombosis.
    JAMA, 2011, Oct-26, Volume: 306, Issue:16

    Topics: Aged; Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Case-Control Studies; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Cytochrome P-450 CYP2C19; DNA; Female; France; Genetic Predisposition to Disease; Genotype; Humans; Integrin beta3; Male; Middle Aged; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Prognosis; Proton Pump Inhibitors; Risk Factors; Stents; Thrombosis; Ticlopidine

2011
Increased clopidogrel response is associated with ABCC3 expression: a pilot study.
    Clinica chimica acta; international journal of clinical chemistry, 2012, Feb-18, Volume: 413, Issue:3-4

    Topics: Aged; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Clopidogrel; Coronary Artery Disease; Gene Expression Regulation; Humans; Leukocytes, Mononuclear; Male; Middle Aged; Multidrug Resistance-Associated Proteins; Pilot Projects; RNA, Messenger; Ticlopidine; Treatment Outcome

2012
Coronary artery stents and antiplatelet therapy in patients with cirrhosis.
    Journal of clinical gastroenterology, 2012, Volume: 46, Issue:4

    Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Fatty Liver; Female; Follow-Up Studies; Gastrointestinal Hemorrhage; Humans; Liver Cirrhosis; Liver Transplantation; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Platelet Aggregation Inhibitors; Retrospective Studies; Risk Factors; Stents; Ticlopidine

2012
Prognostic implications of early and long-term bleeding events in patients on one-year dual antiplatelet therapy following drug-eluting stent implantation.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2012, Sep-01, Volume: 80, Issue:3

    Topics: Aged; Aspirin; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug Therapy, Combination; Drug-Eluting Stents; Female; Hemorrhage; Humans; Incidence; Italy; Kaplan-Meier Estimate; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prevalence; Prosthesis Design; Registries; Risk Assessment; Risk Factors; Severity of Illness Index; Ticlopidine; Time Factors; Treatment Outcome

2012
Relationship between cytochrome P450 2C19*2 polymorphism and stent thrombosis following percutaneous coronary intervention in Chinese patients receiving clopidogrel.
    The Journal of international medical research, 2011, Volume: 39, Issue:5

    Topics: Aged; Aged, 80 and over; Amplified Fragment Length Polymorphism Analysis; Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; China; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Cytochrome P-450 CYP2C19; Drug-Eluting Stents; Female; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Multivariate Analysis; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Proportional Hazards Models; Ticlopidine

2011
Clopidogrel use and early outcomes among older patients receiving a drug-eluting coronary artery stent.
    Circulation. Cardiovascular quality and outcomes, 2012, Volume: 5, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Blood Vessel Prosthesis Implantation; Clopidogrel; Coronary Artery Disease; Coronary Vessels; Dementia; Drug-Eluting Stents; Female; Humans; Male; Medicare Part D; Medication Adherence; Platelet Aggregation Inhibitors; Retrospective Studies; Survival Analysis; Thrombosis; Ticlopidine; United States

2012
Renal function assessed using cystatin C and antiplatelet efficacy of clopidogrel assessed using the vasodilator-stimulated phosphoprotein index in patients having percutaneous coronary intervention.
    The American journal of cardiology, 2012, Mar-01, Volume: 109, Issue:5

    Topics: Aged; Angioplasty, Balloon, Coronary; Blood Proteins; Cell Adhesion Molecules; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Cystatin C; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Glomerular Filtration Rate; Humans; Immunoassay; Kidney Function Tests; Male; Microfilament Proteins; Phosphoproteins; Platelet Aggregation Inhibitors; Prognosis; Stents; Ticlopidine

2012
Effect of individual proton pump inhibitors on cardiovascular events in patients treated with clopidogrel following coronary stenting: results from the Ibaraki Cardiac Assessment Study Registry.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2012, Oct-01, Volume: 80, Issue:4

    Topics: Aged; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Drug Interactions; Female; Gastrointestinal Hemorrhage; Humans; Incidence; Japan; Kaplan-Meier Estimate; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Propensity Score; Proportional Hazards Models; Proton Pump Inhibitors; Registries; Retrospective Studies; Risk Assessment; Risk Factors; Stents; Ticlopidine; Time Factors; Treatment Outcome

2012
Phenotyping vs. genotyping for prediction of clopidogrel efficacy and safety: the PEGASUS-PCI study.
    Journal of thrombosis and haemostasis : JTH, 2012, Volume: 10, Issue:4

    Topics: Aged; Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; Austria; Blood Platelets; Cardiovascular Diseases; Cell Adhesion Molecules; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Female; Gene Frequency; Genotype; Hemorrhage; Humans; Kaplan-Meier Estimate; Logistic Models; Male; Microfilament Proteins; Middle Aged; Multivariate Analysis; Pharmacogenetics; Phenotype; Phosphoproteins; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Polymorphism, Genetic; Predictive Value of Tests; Prospective Studies; Risk Assessment; Risk Factors; Sensitivity and Specificity; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome

2012
Extension of Kaplan-Meier methods in observational studies with time-varying treatment.
    Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 2012, Volume: 15, Issue:1

    Topics: Age Factors; Aged; Clopidogrel; Comorbidity; Confounding Factors, Epidemiologic; Coronary Artery Disease; Drug-Eluting Stents; Female; Health Behavior; Hemorrhage; Humans; Kaplan-Meier Estimate; Male; Medication Adherence; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Sex Factors; Ticlopidine; Time Factors

2012
Vasodilator-stimulated phosphoprotein-phosphorylation assay in patients on clopidogrel: does standardisation matter?
    Thrombosis and haemostasis, 2012, Volume: 107, Issue:3

    Topics: Blood Specimen Collection; Cell Adhesion Molecules; Cell Separation; Clopidogrel; Coronary Artery Disease; Flow Cytometry; Humans; Microfilament Proteins; Observer Variation; Phosphoproteins; Phosphorylation; Platelet Activation; Platelet Function Tests; Prospective Studies; Reference Standards; Ticlopidine; Vasodilator Agents

2012
Desensitization to prasugrel: cardiology's increased need for allergy consultation.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2012, Volume: 108, Issue:2

    Topics: Atherectomy, Coronary; Blood Vessel Prosthesis Implantation; Clopidogrel; Coronary Artery Disease; Desensitization, Immunologic; Drug Dosage Calculations; Drug Hypersensitivity; Humans; Male; Middle Aged; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Referral and Consultation; Stents; Thiophenes; Ticlopidine

2012
Management of a hypersensitivity reaction to thienopyridines: prasugrel-induced fever and hepatitis resolved after switching to clopidogrel.
    Revista espanola de cardiologia (English ed.), 2012, Volume: 65, Issue:8

    Topics: Adult; Clopidogrel; Coronary Artery Disease; Drug Hypersensitivity; Female; Fever; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Thiophenes; Ticlopidine

2012
Serotonin antagonism improves platelet inhibition in clopidogrel low-responders after coronary stent placement: an in vitro pilot study.
    PloS one, 2012, Volume: 7, Issue:2

    Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Female; Humans; In Vitro Techniques; Ketanserin; Light; Male; Middle Aged; Myocardial Infarction; Pilot Projects; Platelet Aggregation; Platelet Aggregation Inhibitors; Serotonin; Serotonin Antagonists; Stents; Ticlopidine; Treatment Outcome

2012
Cigarette smoking is associated with a dose-response effect in clopidogrel-treated patients with diabetes mellitus and coronary artery disease: results of a pharmacodynamic study.
    JACC. Cardiovascular interventions, 2012, Volume: 5, Issue:3

    Topics: Aged; Aspirin; Biomarkers; Blood Platelets; Cell Adhesion Molecules; Clopidogrel; Coronary Artery Disease; Cotinine; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Florida; Humans; Male; Microfilament Proteins; Middle Aged; Odds Ratio; Phosphoproteins; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Smoking; Ticlopidine; Time Factors; Treatment Outcome

2012
Comparison of additional versus no additional heparin during therapeutic oral anticoagulation in patients undergoing percutaneous coronary intervention.
    The American journal of cardiology, 2012, Jul-01, Volume: 110, Issue:1

    Topics: Administration, Oral; Aged; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Female; Fibrinolytic Agents; Follow-Up Studies; Heparin; Humans; Injections, Subcutaneous; Male; Platelet Aggregation Inhibitors; Postoperative Complications; Preoperative Care; Prospective Studies; Thrombosis; Ticlopidine; Time Factors; Treatment Outcome; Warfarin

2012
Effects of PPIs and an H2 blocker on the antiplatelet function of clopidogrel in Japanese patients under dual antiplatelet therapy.
    Journal of atherosclerosis and thrombosis, 2012, Volume: 19, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Asian People; Aspirin; Case-Control Studies; Clopidogrel; Coronary Artery Disease; Cross-Over Studies; Drug Therapy, Combination; Enzyme Inhibitors; Female; Histamine H2 Antagonists; Humans; Male; Omeprazole; Platelet Aggregation; Platelet Aggregation Inhibitors; Prognosis; Prospective Studies; Proton Pump Inhibitors; Rabeprazole; Ticlopidine

2012
[Effect of clopidogrel combined with calcium-channel blocker on coronary artery disease in elderly patients: a propensity score-based retrospective cohort study].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2012, Volume: 32, Issue:4

    Topics: Aged; Aged, 80 and over; Calcium Channel Blockers; Clopidogrel; Cohort Studies; Coronary Artery Disease; Drug Therapy, Combination; Humans; Middle Aged; Propensity Score; Retrospective Studies; Ticlopidine

2012
High platelet reactivity on clopidogrel therapy correlates with increased coronary atherosclerosis and calcification: a volumetric intravascular ultrasound study.
    JACC. Cardiovascular imaging, 2012, Volume: 5, Issue:5

    Topics: Aged; Angioplasty, Balloon, Coronary; Blood Platelets; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Coronary Vessels; Drug Resistance; Female; Humans; Least-Squares Analysis; Linear Models; Male; Middle Aged; Multivariate Analysis; New York City; Plaque, Atherosclerotic; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Registries; Risk Assessment; Risk Factors; Severity of Illness Index; Ticlopidine; Time Factors; Treatment Outcome; Ultrasonography, Interventional; Vascular Calcification

2012
Blockbuster interactions: are they bad for the patient?
    European heart journal, 2012, Volume: 33, Issue:17

    Topics: Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP3A; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine

2012
[Comparison on the effects of clopidogrel, statins combination in treating coronary artery disease among the elderly patients: a retrospective cohort study].
    Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi, 2012, Volume: 33, Issue:3

    Topics: Aged; Aged, 80 and over; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Retrospective Studies; Ticlopidine

2012
Duration of dual antiplatelet therapy and long-term clinical outcome after coronary drug-eluting stent implantation: landmark analyses from the CREDO-Kyoto PCI/CABG Registry Cohort-2.
    Circulation. Cardiovascular interventions, 2012, Volume: 5, Issue:3

    Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Chi-Square Distribution; Clopidogrel; Cohort Studies; Coronary Artery Disease; Drug Administration Schedule; Drug Therapy, Combination; Drug-Eluting Stents; Female; Hemorrhage; Humans; Japan; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Proportional Hazards Models; Prosthesis Design; Pyridines; Registries; Stroke; Ticlopidine; Time Factors; Treatment Outcome

2012
[Omega-3--clopidogrel can help!].
    Kardiologia polska, 2012, Volume: 70, Issue:5

    Topics: Aryl Hydrocarbon Hydroxylases; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Fatty Acids, Omega-3; Female; Humans; Male; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Ticlopidine

2012
Fractalkine activates a signal transduction pathway similar to P2Y12 and is associated with impaired clopidogrel responsiveness.
    Arteriosclerosis, thrombosis, and vascular biology, 2012, Volume: 32, Issue:8

    Topics: Adenosine Diphosphate; Alprostadil; Chemokine CX3CL1; Clopidogrel; Coronary Artery Disease; Humans; Phosphatidylinositol 3-Kinases; Phosphorylation; Platelet Activation; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Signal Transduction; Ticlopidine

2012
CYP2C19 genotype-guided antiplatelet therapy in a patient with clopidogrel resistance.
    Connecticut medicine, 2012, Volume: 76, Issue:5

    Topics: Aged; Aryl Hydrocarbon Hydroxylases; Aspirin; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Drug Resistance; Genotype; Humans; Male; Piperazines; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Stents; Thiophenes; Ticlopidine; Treatment Outcome

2012
Relationship between cytochrome P450 2C19*17 genotype distribution, platelet aggregation and bleeding risk in patients with blood stasis syndrome of coronary artery disease treated with clopidogrel.
    Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, 2012, Volume: 10, Issue:6

    Topics: Aged; Aryl Hydrocarbon Hydroxylases; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Female; Genotype; Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation; Ticlopidine

2012
Clopidogrel resistance in North Indian patients of coronary artery disease and lack of its association with platelet ADP receptors P2Y1 and P2Y12 gene polymorphisms.
    Platelets, 2013, Volume: 24, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Clopidogrel; Coronary Artery Disease; Drug Resistance; Female; Haplotypes; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Ticlopidine; Treatment Outcome

2013
Safety of temporary and permanent suspension of antiplatelet therapy after drug eluting stent implantation in contemporary "real-world" practice.
    Journal of interventional cardiology, 2012, Volume: 25, Issue:5

    Topics: Aged; Analysis of Variance; Aspirin; Clopidogrel; Coronary Artery Disease; Drug-Eluting Stents; Female; Health Status Indicators; Humans; Male; Platelet Aggregation Inhibitors; Practice Patterns, Physicians'; Prospective Studies; Risk Assessment; Ticlopidine; Time Factors

2012
Medium to long-term clinical outcomes with everolimus-eluting stents in real-life percutaneous coronary intervention.
    Annals of the Academy of Medicine, Singapore, 2012, Volume: 41, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Drug-Eluting Stents; Everolimus; Female; Humans; Immunosuppressive Agents; Male; Middle Aged; New Zealand; Platelet Aggregation Inhibitors; Registries; Retrospective Studies; Sirolimus; Survival Analysis; Ticlopidine; Time Factors; Treatment Outcome

2012
Complex coronary lesions and rotational atherectomy: one hospital's experience.
    Journal of Zhejiang University. Science. B, 2012, Volume: 13, Issue:8

    Topics: Aged; Angiography; Aspirin; Atherectomy, Coronary; Cardiology; Clopidogrel; Comorbidity; Coronary Artery Disease; Drug-Eluting Stents; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Radiography, Interventional; Retrospective Studies; Ticlopidine; Treatment Outcome

2012
Atopaxar: a review of its mechanism of action and role in patients with coronary artery disease.
    Future cardiology, 2012, Volume: 8, Issue:4

    Topics: Acute Coronary Syndrome; Animals; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Humans; Imines; Platelet Activation; Platelet Aggregation Inhibitors; Pyridines; Receptors, Thrombin; Ticlopidine

2012
Impact of proton pump inhibitors or famotidine on the antiplatelet actions during dual-antiplatelet therapy in Japanese patients.
    Cardiovascular intervention and therapeutics, 2013, Volume: 28, Issue:1

    Topics: Aged; Asian People; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug Interactions; Famotidine; Female; Histamine H2 Antagonists; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Proton Pump Inhibitors; Ticlopidine

2013
Early and late outcome associated with bleeding events in the setting of dual antiplatelet therapy following stent placement.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2012, Sep-01, Volume: 80, Issue:3

    Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug-Eluting Stents; Female; Hemorrhage; Humans; Male; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Ticlopidine

2012
Less may be more: insights on dual antiplatelet therapy duration after drug-eluting stent implantation from the MATRIX registry.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2012, Sep-01, Volume: 80, Issue:3

    Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug-Eluting Stents; Female; Humans; Male; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Tacrolimus; Ticlopidine

2012
Clinical efficacy and safety of biodegradable polymer-based sirolimus-eluting stents in patients with diabetes mellitus insight from the 4-year results of the create study.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2013, Jun-01, Volume: 81, Issue:7

    Topics: Absorbable Implants; Aged; Aspirin; Cardiovascular Agents; Chi-Square Distribution; Clopidogrel; Coronary Artery Disease; Diabetes Mellitus; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Kaplan-Meier Estimate; Logistic Models; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Odds Ratio; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Polymers; Prospective Studies; Prosthesis Design; Registries; Risk Assessment; Risk Factors; Sirolimus; Ticlopidine; Time Factors; Treatment Outcome

2013
Femoral pseudoaneurysm with a communicating arteriovenous fistula: a complication after percutaneous coronary intervention.
    Circulation, 2012, Sep-11, Volume: 126, Issue:11

    Topics: Aneurysm, False; Angioplasty, Balloon, Coronary; Arteriovenous Fistula; Aspirin; Clopidogrel; Comorbidity; Coronary Artery Disease; Drug Therapy, Combination; Femoral Artery; Fibrinolytic Agents; Humans; Male; Middle Aged; Ticlopidine; Treatment Outcome

2012
Dual antiplatelet therapy after drug-eluting stent implantation: is it time to slacken the reins?
    Journal of the American College of Cardiology, 2012, Oct-09, Volume: 60, Issue:15

    Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Stenosis; Drug-Eluting Stents; Female; Humans; Male; Medication Adherence; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Sirolimus; Ticlopidine; Withholding Treatment

2012
Double antiplatelet therapy after drug-eluting stent implantation: risk associated with discontinuation within the first year.
    Journal of the American College of Cardiology, 2012, Oct-09, Volume: 60, Issue:15

    Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Male; Medication Adherence; Middle Aged; Platelet Aggregation Inhibitors; Prognosis; Retrospective Studies; Risk Factors; Spain; Survival Rate; Ticlopidine; Time Factors

2012
Three years ago I received a drug-coated stent and was put on aspirin and Plavix. My cardiologist recently retired, and my new cardiologist told me to stop taking Plavix. It scares me to death. I read the story you released in February about the danger
    Heart advisor, 2011, Volume: 14, Issue:7

    Topics: Clopidogrel; Contraindications; Coronary Artery Disease; Drug-Eluting Stents; Humans; Platelet Aggregation Inhibitors; Ticlopidine; Withholding Treatment

2011
Antithrombotic therapy for atrial fibrillation and coronary artery disease in older patients.
    American heart journal, 2012, Volume: 164, Issue:4

    Topics: Age Factors; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Coronary Artery Disease; Diabetes Complications; Female; Fibrinolytic Agents; Heart Failure; Humans; Hypertension; Male; Risk Assessment; Stroke; Ticlopidine; Treatment Outcome; Warfarin

2012
Dual antiplatelet agent-induced spontaneous liver hematoma.
    The Annals of pharmacotherapy, 2012, Volume: 46, Issue:11

    Topics: Aged; Aspirin; Chemical and Drug Induced Liver Injury; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Hematoma; Humans; Male; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Ticlopidine

2012
Reduction in platelet reactivity with prasugrel 5 mg in low-body-weight patients is noninferior to prasugrel 10 mg in higher-body-weight patients: results from the FEATHER trial.
    Journal of the American College of Cardiology, 2012, Nov-13, Volume: 60, Issue:20

    Topics: Adolescent; Adult; Aged; Blood Platelets; Body Weight; Clopidogrel; Coronary Artery Disease; Cross-Over Studies; Female; Humans; Male; Middle Aged; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Single-Blind Method; Thiophenes; Ticlopidine; Young Adult

2012
Evaluating the impact of public health notification: Duke clopidogrel experience.
    Circulation. Cardiovascular quality and outcomes, 2012, Volume: 5, Issue:6

    Topics: Access to Information; Aged; Clopidogrel; Coronary Artery Disease; Drug Administration Schedule; Drug Information Services; Drug-Eluting Stents; Evidence-Based Medicine; Female; Humans; Logistic Models; Male; Metals; Middle Aged; North Carolina; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Proportional Hazards Models; Prosthesis Design; Public Health Informatics; Registries; Stents; Ticlopidine; Time Factors; Treatment Outcome

2012
The functional G143E variant of carboxylesterase 1 is associated with increased clopidogrel active metabolite levels and greater clopidogrel response.
    Pharmacogenetics and genomics, 2013, Volume: 23, Issue:1

    Topics: Carboxylic Ester Hydrolases; Clopidogrel; Coronary Artery Disease; DNA; Female; Genotype; Heterozygote; Humans; Male; Middle Aged; Pharmacogenetics; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymerase Chain Reaction; Polymorphism, Genetic; Prognosis; Ticlopidine

2013
[Expert answer. Coronary artery patients with atrial fibrillation on anticoagulation treatment may need antithrombotic treatment. What kind is there?].
    Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir, 2012, Volume: 40, Issue:4

    Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Ticlopidine; Warfarin

2012
A new generation of biodegradable polymer-coated sirolimus-eluting stents for the treatment of coronary artery disease: final 5-year clinical outcomes from the CREATE study.
    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2012, Nov-22, Volume: 8, Issue:7

    Topics: Absorbable Implants; Aged; Aspirin; Cardiovascular Agents; China; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Disease-Free Survival; Drug Therapy, Combination; Drug-Eluting Stents; Female; Heart Failure; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Polymers; Propensity Score; Proportional Hazards Models; Prospective Studies; Prosthesis Design; Registries; Risk Assessment; Risk Factors; Sirolimus; Ticlopidine; Time Factors; Treatment Outcome

2012
I'm having a stent put in one of my coronary arteries soon and I wonder how long I will need to be on clopidogrel. Does it depend on the kind of stent?
    Heart advisor, 2010, Volume: 13, Issue:12

    Topics: Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Artery Disease; Drug Administration Schedule; Humans; Platelet Aggregation Inhibitors; Stents; Ticlopidine

2010
Chest pain in a patient with coronary artery disease taking clopidogrel.
    Gastroenterology, 2013, Volume: 144, Issue:1

    Topics: Chest Pain; Clopidogrel; Coronary Artery Disease; Esophageal Diseases; Esophagoscopy; Hematoma; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine; Tomography, X-Ray Computed

2013
Differential prognostic impact of high on-treatment platelet reactivity among patients with acute coronary syndromes versus stable coronary artery disease undergoing percutaneous coronary intervention.
    American heart journal, 2013, Volume: 165, Issue:1

    Topics: Acute Coronary Syndrome; Aged; Clopidogrel; Coronary Artery Disease; Female; Follow-Up Studies; Hemorrhage; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Platelet Function Tests; Prognosis; Stroke; Thrombosis; Ticlopidine; Treatment Outcome

2013
Triple antiplatelet therapy with cilostazol: hitting the "sweet-spot".
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2013, Jan-01, Volume: 81, Issue:1

    Topics: Aspirin; Blood Platelets; Cilostazol; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Tetrazoles; Ticlopidine

2013
Decreased plasma IL-35 levels are related to the left ventricular ejection fraction in coronary artery diseases.
    PloS one, 2012, Volume: 7, Issue:12

    Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Cytokines; Female; Humans; Interleukins; Male; Middle Aged; Statistics, Nonparametric; Stroke Volume; Ticlopidine

2012
Elevated plasma fibrinogen rather than residual platelet reactivity after clopidogrel pre-treatment is associated with an increased ischemic risk during elective percutaneous coronary intervention.
    Journal of the American College of Cardiology, 2013, Jan-08, Volume: 61, Issue:1

    Topics: Aged; Blood Platelets; C-Reactive Protein; Clopidogrel; Coronary Artery Disease; Creatine Kinase, MB Form; Female; Fibrinogen; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Platelet Count; Platelet Function Tests; Predictive Value of Tests; Premedication; Prospective Studies; ROC Curve; Sensitivity and Specificity; Ticlopidine; Troponin

2013
Human platelet protease-activated receptor-1 responsiveness to thrombin related to P2Y12 inhibition.
    Translational research : the journal of laboratory and clinical medicine, 2013, Volume: 161, Issue:5

    Topics: Adenosine Diphosphate; Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Models, Cardiovascular; Platelet Activation; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Receptor, PAR-1; Receptors, Purinergic P2Y12; Thrombin; Thromboembolism; Ticlopidine; Translational Research, Biomedical

2013
Risk factors for upper gastrointestinal bleeding in coronary artery disease patients receiving both aspirin and clopidogrel.
    Journal of the Chinese Medical Association : JCMA, 2013, Volume: 76, Issue:1

    Topics: Aged; Aged, 80 and over; Aspirin; Clopidogrel; Coronary Artery Disease; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Proportional Hazards Models; Retrospective Studies; Risk Factors; Ticlopidine; Upper Gastrointestinal Tract

2013
The CYP2C19 genotype does not impact the long-term prognosis of patients with coronary artery disease.
    Atherosclerosis, 2013, Volume: 227, Issue:1

    Topics: Adult; Aged; Aryl Hydrocarbon Hydroxylases; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP2C19; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Prodrugs; Prognosis; Ticlopidine

2013
Chronic kidney disease--is it a true risk factor of reduced clopidogrel efficacy in elderly patients with stable coronary artery disease?
    Thrombosis research, 2013, Volume: 131, Issue:3

    Topics: Aged, 80 and over; Blood Platelets; Clopidogrel; Coronary Artery Disease; Creatinine; Female; Hemoglobins; Humans; Male; Odds Ratio; P-Selectin; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptors, Purinergic P2Y12; Regression Analysis; Renal Insufficiency, Chronic; Risk Factors; Ticlopidine; Treatment Outcome

2013
Characterization of aspirin allergies in patients with coronary artery disease.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2013, Volume: 110, Issue:2

    Topics: Aged; Aged, 80 and over; Aspirin; California; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Drug Hypersensitivity; Female; Humans; Male; Retrospective Studies; Ticlopidine

2013
A case of in-stent thrombosis in a patient with drug eluting stents during perioperative management with glycoprotein IIb/IIIa inhibitors.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2013, Dec-01, Volume: 82, Issue:7

    Topics: Aged; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Coronary Thrombosis; Drug Substitution; Drug Therapy, Combination; Drug-Eluting Stents; Eptifibatide; Female; Humans; Neurosurgical Procedures; Peptides; Percutaneous Coronary Intervention; Perioperative Period; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Ticlopidine; Time Factors; Treatment Outcome; Ultrasonography, Interventional

2013
Effect of clopidogrel on platelet aggregation and plasma concentration of fibrinogen in subjects with cerebral or coronary atherosclerotic disease.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2002, Volume: 8, Issue:4

    Topics: Clopidogrel; Coronary Artery Disease; Fibrinogen; Humans; Intracranial Arteriosclerosis; Platelet Aggregation; Ticlopidine

2002
Clopidogrel but not aspirin reduces P-selectin expression and formation of platelet-leukocyte aggregates in patients with atherosclerotic vascular disease.
    Clinical pharmacology and therapeutics, 2003, Volume: 73, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Blood Platelets; Case-Control Studies; Clopidogrel; Coronary Artery Disease; Cross-Sectional Studies; Drug Therapy, Combination; Dual Specificity Phosphatase 2; Female; Flow Cytometry; Humans; Intercellular Adhesion Molecule-1; Leukocytes; Male; Middle Aged; P-Selectin; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Phosphatase 2; Protein Tyrosine Phosphatases; Ticlopidine

2003
[Effects of antiaggregants on concentration of plasma cytokines in patients with acute coronary syndrome].
    Klinicheskaia meditsina, 2003, Volume: 81, Issue:6

    Topics: Acute Disease; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Cytokines; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine

2003
[Sudden edema and pain in the knee].
    Duodecim; laaketieteellinen aikakauskirja, 2003, Volume: 119, Issue:17

    Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Interactions; Drug Therapy, Combination; Edema; Hemorrhage; Humans; Knee Joint; Male; Pain; Platelet Aggregation Inhibitors; Radiography; Ticlopidine

2003
Aspirin resistance is associated with a high incidence of myonecrosis after non-urgent percutaneous coronary intervention despite clopidogrel pretreatment.
    Journal of the American College of Cardiology, 2004, Mar-17, Volume: 43, Issue:6

    Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Creatine Kinase; Creatine Kinase, MB Form; Drug Resistance; Female; Humans; Incidence; Isoenzymes; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Postoperative Period; Sex Factors; Ticlopidine; Troponin I

2004
Clopidogrel resistance is associated with increased risk of recurrent atherothrombotic events in patients with acute myocardial infarction.
    Circulation, 2004, Jun-29, Volume: 109, Issue:25

    Topics: Adenosine Diphosphate; Aged; Aspirin; Biotransformation; Clopidogrel; Combined Modality Therapy; Coronary Artery Disease; Coronary Restenosis; Coronary Thrombosis; Drug Resistance; Drug Therapy, Combination; Epinephrine; Eptifibatide; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Infarction; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Prodrugs; Prospective Studies; Purinergic P2 Receptor Antagonists; Recurrence; Risk; Smoking; Stents; Ticlopidine; Treatment Outcome

2004
The effect of clopidogrel on apoptosis--an in vivo study.
    Cell biology international, 2004, Volume: 28, Issue:6

    Topics: Adult; Aged; Apoptosis; Cells, Cultured; Clopidogrel; Coronary Artery Disease; DNA; DNA Fragmentation; Electrophoresis, Agar Gel; Female; Humans; Leukocyte Count; Lymphocytes; Male; Middle Aged; Ticlopidine

2004
Coronary spasm in a 59-yr-old woman with hyperventilation.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2004, Volume: 51, Issue:8

    Topics: Alkalosis, Respiratory; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Antihypertensive Agents; Aspirin; Cardiac Catheterization; Clopidogrel; Coronary Artery Disease; Coronary Vasospasm; Diagnosis, Differential; Diltiazem; Electrocardiography; Female; Heparin; Humans; Hyperventilation; Hyponatremia; Middle Aged; Platelet Aggregation Inhibitors; Schizophrenia; Ticlopidine; Water Intoxication

2004
[Antiplatelet therapy in patients with peripheral arterial disease (PAD)].
    Medizinische Klinik (Munich, Germany : 1983), 2004, Aug-15, Volume: 99 Suppl 1

    Topics: Arterial Occlusive Diseases; Aspirin; Cause of Death; Cerebral Infarction; Clopidogrel; Coronary Artery Disease; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk Factors; Survival Rate; Ticlopidine

2004
Evolution of spontaneous atherosclerotic plaque rupture with medical therapy: long-term follow-up with intravascular ultrasound.
    Circulation, 2004, Nov-02, Volume: 110, Issue:18

    Topics: Aged; Aspirin; Biomarkers; Clopidogrel; Coronary Artery Disease; Disease Progression; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Myocardial Ischemia; Platelet Aggregation Inhibitors; Rupture, Spontaneous; Ticlopidine; Troponin I; Ultrasonography, Interventional

2004
[Acute coronary syndrome, stroke, arterial occlusive disease. Bring the patients out of the danger zone!].
    MMW Fortschritte der Medizin, 2004, Volume: 146 Suppl 1

    Topics: Arterial Occlusive Diseases; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Embolism, Cholesterol; Humans; Intracranial Embolism; Myocardial Infarction; Platelet Activation; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine

2004
[Patients with arterial occlusive disease die of myocardial infarct or stroke. The dangerous sisters: arterial occlusive disease and coronary heart disease].
    MMW Fortschritte der Medizin, 2004, Volume: 146 Suppl 1

    Topics: Aged; Arterial Occlusive Diseases; Aspirin; Cause of Death; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Humans; Multicenter Studies as Topic; Myocardial Infarction; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Prognosis; Risk Factors; Stroke; Ticlopidine

2004
Antiplatelet therapy in non-ST-segment elevation acute coronary syndromes.
    JAMA, 2004, Oct-20, Volume: 292, Issue:15

    Topics: Adrenergic beta-Antagonists; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Coronary Thrombosis; Drug Therapy, Combination; Electrocardiography; Eptifibatide; Heparin; Humans; Male; Middle Aged; Myocardial Ischemia; Nitroglycerin; Peptides; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Risk Assessment; Stents; Ticlopidine; Vasodilator Agents

2004
Antiplatelet effects of a 600 mg loading dose of clopidogrel are not attenuated in patients receiving atorvastatin or simvastatin for at least 4 weeks prior to coronary artery stenting.
    European heart journal, 2004, Volume: 25, Issue:21

    Topics: Aged; Atorvastatin; Clopidogrel; Coronary Artery Disease; Drug Interactions; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Platelet Aggregation Inhibitors; Preoperative Care; Prospective Studies; Pyrroles; Simvastatin; Stents; Ticlopidine

2004
High clopidogrel loading dose during coronary stenting: effects on drug response and interindividual variability.
    European heart journal, 2004, Volume: 25, Issue:21

    Topics: Blood Platelets; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; P-Selectin; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoprotein IIb; Risk Factors; Stents; Ticlopidine

2004
Concordance between clopidogrel use and prescribing guidelines.
    Internal medicine journal, 2004, Volume: 34, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Australia; Clopidogrel; Cohort Studies; Coronary Artery Disease; Cost-Benefit Analysis; Cross-Sectional Studies; Drug Prescriptions; Drug Utilization Review; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Practice Patterns, Physicians'; Ticlopidine

2004
Why don't we practice evidence-based medicine?
    The Journal of invasive cardiology, 2005, Volume: 17, Issue:1

    Topics: Clopidogrel; Coronary Angiography; Coronary Artery Bypass; Coronary Artery Disease; Evidence-Based Medicine; Health Knowledge, Attitudes, Practice; Hospitalization; Humans; Platelet Aggregation Inhibitors; Ticlopidine; Ventricular Dysfunction, Left

2005
Impact of continued hospitalization in patients pre-treated with clopidogrel prior to coronary angiography and undergoing coronary artery bypass grafting.
    The Journal of invasive cardiology, 2005, Volume: 17, Issue:1

    Topics: Aged; Clopidogrel; Coronary Angiography; Coronary Artery Bypass; Coronary Artery Disease; Female; Hospitalization; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Retrospective Studies; Survival Analysis; Ticlopidine; Treatment Outcome; Ventricular Dysfunction, Left

2005
Reasons for inability of clopidogrel to inhibit platelet aggregation early after coronary artery bypass surgery.
    The Journal of thoracic and cardiovascular surgery, 2005, Volume: 129, Issue:2

    Topics: Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine; Time Factors

2005
Rapid desensitization procedure for patients with aspirin hypersensitivity undergoing coronary stenting.
    The American journal of cardiology, 2005, Feb-15, Volume: 95, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Coronary Artery Disease; Desensitization, Immunologic; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Hypersensitivity; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Stents; Ticlopidine

2005
Oral antiplatelet therapy.
    JAMA, 2005, Feb-16, Volume: 293, Issue:7

    Topics: Cerebrovascular Disorders; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Humans; Platelet Aggregation Inhibitors; Salicylates; Ticlopidine

2005
Oral antiplatelet therapy.
    JAMA, 2005, Feb-16, Volume: 293, Issue:7

    Topics: Aspirin; Cerebrovascular Disorders; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Dipyridamole; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Ticlopidine

2005
Raising the loading dose of clopidogrel: aiming at the proper target?
    European heart journal, 2005, Volume: 26, Issue:7

    Topics: Clopidogrel; Coronary Artery Disease; Humans; Platelet Aggregation Inhibitors; Stents; Ticlopidine

2005
Multiple antiplatelet effects of clopidogrel are not modulated by statin type in patients undergoing percutaneous coronary intervention.
    Platelets, 2004, Volume: 15, Issue:8

    Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Atorvastatin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug Evaluation; Drug Interactions; Drug Therapy, Combination; Fatty Acids, Monounsaturated; Female; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Pravastatin; Pyrroles; Simvastatin; Ticlopidine

2004
Drug therapy during percutaneous coronary interventions in stable and unstable coronary artery disease: the Italian Drug Evaluation in Angioplasty (IDEA) study.
    Italian heart journal : official journal of the Italian Federation of Cardiology, 2005, Volume: 6, Issue:2

    Topics: Acetylcysteine; Adrenergic beta-Antagonists; Aged; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Utilization Review; Female; Health Care Surveys; Heparin; Humans; Italy; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Practice Guidelines as Topic; Pyridines; Registries; Ticlopidine

2005
Variation in the ability of glycoprotein IIb-IIIa antagonists to exert and maintain their inhibitory effects on the binding of fibrinogen.
    Journal of cardiovascular pharmacology, 2005, Volume: 46, Issue:1

    Topics: Adenosine Diphosphate; Aged; Binding, Competitive; Blood Platelets; Clopidogrel; Coronary Artery Disease; Data Interpretation, Statistical; Eptifibatide; Fibrinogen; Flow Cytometry; Fluorescein-5-isothiocyanate; Humans; Iodine Radioisotopes; Male; Peptide Fragments; Peptides; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Receptors, Thrombin; Ticlopidine; Tirofiban; Tyrosine

2005
Ask the doctors. My mother in her early 90s has been diagnosed with atherosclerosis, had a successful angioplasty a year ago for severe chest pain, takes clopidogrel and aspirin, and in general eats a low-fat diet, although she really likes melted ice cre
    Heart advisor, 2005, Volume: 8, Issue:5

    Topics: Aged; Aged, 80 and over; Aspirin; Clopidogrel; Coronary Artery Disease; Diet, Fat-Restricted; Exercise; Female; Humans; Hypolipidemic Agents; Ice Cream; Platelet Aggregation Inhibitors; Ticlopidine

2005
Lack of association between the P2Y12 receptor gene polymorphism and platelet response to clopidogrel in patients with coronary artery disease.
    Thrombosis research, 2005, Volume: 116, Issue:6

    Topics: Aged; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Membrane Proteins; Middle Aged; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Ticlopidine

2005
Antiplatelet therapy and the vascular tree.
    Heart (British Cardiac Society), 2006, Volume: 92, Issue:1

    Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Combined Modality Therapy; Coronary Artery Disease; Drug Resistance; Drug Therapy, Combination; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Stroke; Ticlopidine

2006
Interpretation of clopidogrel resistance.
    Kardiologia polska, 2005, Volume: 63, Issue:4

    Topics: Blood Platelets; Clopidogrel; Coronary Artery Disease; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Ticlopidine

2005
Cost-effectiveness of the Taxus paclitaxel-eluting stent in the Swedish healthcare system.
    Scandinavian cardiovascular journal : SCJ, 2006, Volume: 40, Issue:1

    Topics: Clinical Trials as Topic; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Cost-Benefit Analysis; Delivery of Health Care; Drug Delivery Systems; Health Care Costs; Humans; Models, Economic; Myocardial Revascularization; Paclitaxel; Reoperation; Stents; Sweden; Taxus; Ticlopidine

2006
Clopidogrel withdrawal is associated with proinflammatory and prothrombotic effects in patients with diabetes and coronary artery disease.
    Diabetes, 2006, Volume: 55, Issue:3

    Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Diabetes Complications; Diabetes Mellitus; Female; Humans; Inflammation; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Substance Withdrawal Syndrome; Thrombosis; Ticlopidine

2006
[Postoperative antithrombotic treatment in diabetic patients].
    Clinical research in cardiology : official journal of the German Cardiac Society, 2006, Volume: 95 Suppl 1

    Topics: Anticoagulants; Aspirin; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Diabetes Mellitus; Fibrinolytic Agents; Humans; Platelet Aggregation Inhibitors; Postoperative Complications; Risk Factors; Thrombosis; Ticlopidine; Warfarin

2006
Differential antiplatelet effects of angiotensin converting enzyme inhibitors: comparison of ex vivo platelet aggregation in cardiovascular patients with ramipril, captopril and enalapril.
    Clinical research in cardiology : official journal of the German Cardiac Society, 2006, Volume: 95, Issue:4

    Topics: Adenosine Diphosphate; Aged; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Captopril; Cardiovascular Diseases; Clopidogrel; Collagen; Coronary Artery Disease; Electric Impedance; Enalapril; Female; Fibrinolytic Agents; Germany; Humans; Hypertension; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Ramipril; Ticlopidine; Treatment Outcome

2006
Contribution of gene sequence variations of the hepatic cytochrome P450 3A4 enzyme to variability in individual responsiveness to clopidogrel.
    Arteriosclerosis, thrombosis, and vascular biology, 2006, Volume: 26, Issue:8

    Topics: Adenine; Alleles; Anticoagulants; Aspirin; Blood Platelets; Clopidogrel; Cohort Studies; Coronary Artery Disease; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Genetic Variation; Genotype; Guanine; Humans; Introns; Liver; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Polymorphism, Genetic; Ticlopidine

2006
Clopidogrel desensitization.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2006, Volume: 96, Issue:5

    Topics: Aged; Angioplasty; Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Desensitization, Immunologic; Humans; Male; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Urticaria

2006
Late in-stent thrombosis in a patient with systemic lupus erythematosus and hyperhomocysteinemia while on clopidogrel and aspirin.
    The Journal of invasive cardiology, 2006, Volume: 18, Issue:6

    Topics: Angioplasty, Balloon, Coronary; Aspirin; Blood Coagulation Disorders; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Female; Humans; Hyperhomocysteinemia; Lupus Erythematosus, Systemic; Middle Aged; Platelet Aggregation Inhibitors; Stents; Ticlopidine; Time Factors

2006
Residual arachidonic acid-induced platelet activation via an adenosine diphosphate-dependent but cyclooxygenase-1- and cyclooxygenase-2-independent pathway: a 700-patient study of aspirin resistance.
    Circulation, 2006, Jun-27, Volume: 113, Issue:25

    Topics: Adenosine Diphosphate; Arachidonic Acid; Aspirin; Clopidogrel; Coronary Artery Disease; Cyclooxygenase 1; Cyclooxygenase 2; Dose-Response Relationship, Drug; Drug Resistance; Female; Flow Cytometry; Humans; Male; Middle Aged; Multivariate Analysis; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Recurrence; Signal Transduction; Thrombosis; Thromboxane B2; Ticlopidine; Time Factors; Treatment Refusal

2006
Prasugrel, clopidogrel, and combining Swedish apples with American oranges.
    European heart journal, 2006, Volume: 27, Issue:15

    Topics: Clinical Trials, Phase II as Topic; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Humans; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Thiophenes; Ticlopidine

2006
[Combination of clopidogrel and aspirin was no better than aspirin alone for prevention of atherothrombotic events in stable patients. Results of CHARISMA].
    Kardiologiia, 2006, Volume: 46, Issue:5

    Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Severity of Illness Index; Ticlopidine; Treatment Outcome

2006
Viscosity, hemostasis and inflammation in atherosclerotic heart diseases.
    Clinical hemorheology and microcirculation, 2006, Volume: 35, Issue:1-2

    Topics: Aged; Aspirin; Blood Viscosity; Brain Ischemia; Clopidogrel; Coronary Artery Disease; Diabetes Complications; Female; Glucose; Glycated Hemoglobin; Hemostasis; Humans; Inflammation; Male; Middle Aged; Myocardial Ischemia; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine; von Willebrand Factor

2006
The CHARISMA trial and the REACH registry outcomes.
    Journal of the National Medical Association, 2006, Volume: 98, Issue:10

    Topics: Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Humans; Incidence; Platelet Aggregation Inhibitors; Registries; Risk Factors; Ticlopidine; Treatment Outcome

2006
Clopidogrel use and long-term clinical outcomes after drug-eluting stent implantation.
    JAMA, 2007, Jan-10, Volume: 297, Issue:2

    Topics: Aged; Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Artery Disease; Drug Delivery Systems; Female; Humans; Male; Middle Aged; Myocardial Infarction; Paclitaxel; Platelet Aggregation Inhibitors; Sirolimus; Stents; Ticlopidine; Treatment Outcome

2007
Clinical trials update from the annual scientific session of the American College of Cardiology 2006.
    The American journal of cardiology, 2006, Dec-18, Volume: 98, Issue:12A

    Topics: Aspirin; Cardiac Catheterization; Cardiology; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Enoxaparin; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Societies, Medical; Stents; Thrombolytic Therapy; Ticlopidine; United States

2006
Does clopidogrel each day keep stent thrombosis away?
    JAMA, 2007, Jan-10, Volume: 297, Issue:2

    Topics: Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Artery Disease; Drug Delivery Systems; Humans; Paclitaxel; Platelet Aggregation Inhibitors; Sirolimus; Stents; Thrombosis; Ticlopidine

2007
Combination antiplatelet therapy with aspirin and clopidogrel: the role of antecedent and concomitant doses of aspirin. An analysis of 711 patients.
    Cardiology, 2007, Volume: 107, Issue:4

    Topics: Adult; Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Stents; Stroke; Ticlopidine

2007
Severe neutropenia under clopidogrel treatment three weeks after coronary stenting.
    Thrombosis and haemostasis, 2007, Volume: 97, Issue:2

    Topics: Aged; Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Female; Humans; Neutropenia; Platelet Aggregation Inhibitors; Severity of Illness Index; Stents; Ticlopidine; Time Factors

2007
Long-term outcomes in treating left main trifurcation coronary artery disease with the Paclitaxel-eluting stent.
    The Journal of invasive cardiology, 2007, Volume: 19, Issue:2

    Topics: Aged; Catheterization; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Coronary Vessels; Drug Delivery Systems; Female; Humans; Logistic Models; Male; Middle Aged; Paclitaxel; Platelet Aggregation Inhibitors; Retrospective Studies; Stents; Ticlopidine; Treatment Outcome; Tubulin Modulators

2007
Clopidogrel-mediated reduction of circulating tissue factor in patients with stable coronary artery disease.
    European journal of haematology, 2007, Volume: 78, Issue:4

    Topics: Adult; CD40 Ligand; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Solubility; Thromboplastin; Ticlopidine; Treatment Outcome

2007
Determination of aspirin responsiveness by use of whole blood platelet aggregometry.
    Clinical chemistry, 2007, Volume: 53, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Blood Donors; Clopidogrel; Collagen; Coronary Artery Disease; Drug Resistance; Electric Impedance; Female; Humans; In Vitro Techniques; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyridines; Reference Values; Sex Factors; Thromboxane B2; Ticlopidine

2007
Selective serotonin reuptake inhibitors may interfere with the antiplatelet effect of clopidogrel.
    The American journal of cardiology, 2007, Apr-01, Volume: 99, Issue:7

    Topics: Antidepressive Agents, Second-Generation; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Depression; Drug Interactions; Humans; Platelet Aggregation Inhibitors; Prognosis; Selective Serotonin Reuptake Inhibitors; Ticlopidine

2007
Increased incidence of stent thrombosis in patients with cocaine use.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2007, Jun-01, Volume: 69, Issue:7

    Topics: Angina Pectoris; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Cocaine-Related Disorders; Coronary Angiography; Coronary Artery Disease; Coronary Thrombosis; Drug Therapy, Combination; Follow-Up Studies; Hospitals, Urban; Humans; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Research Design; Retrospective Studies; Risk Assessment; Risk Factors; Stents; Ticlopidine; Time Factors; Treatment Outcome; United States

2007
Drug-eluting stents.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2007, May-22, Volume: 176, Issue:11

    Topics: Canada; Clopidogrel; Coronary Artery Disease; Cost-Benefit Analysis; Drug Delivery Systems; Humans; Platelet Aggregation Inhibitors; Stents; Ticlopidine

2007
Patterns of aspirin dosing in non-ST-elevation acute coronary syndromes in the CRUSADE Quality Improvement Initiative.
    The American journal of cardiology, 2007, Jun-01, Volume: 99, Issue:11

    Topics: Acute Disease; Aged; Aged, 80 and over; Angina, Unstable; Aspirin; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Fibrinolytic Agents; Heart Conduction System; Humans; Male; Middle Aged; Patient Discharge; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Quality of Health Care; Retrospective Studies; Syndrome; Ticlopidine; Treatment Outcome; United States

2007
Measuring aspirin resistance, clopidogrel responsiveness, and postprocedural markers of myonecrosis in patients undergoing percutaneous coronary intervention.
    The American journal of cardiology, 2007, Jun-01, Volume: 99, Issue:11

    Topics: Aged; Aged, 80 and over; Analysis of Variance; Angioplasty, Balloon, Coronary; Aspirin; Biomarkers; Clopidogrel; Coronary Artery Disease; Creatine Kinase, MB Form; Drug Resistance; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardium; Necrosis; Platelet Aggregation Inhibitors; Platelet Function Tests; Postoperative Period; Predictive Value of Tests; Proportional Hazards Models; Prospective Studies; Ticlopidine; Treatment Outcome; Troponin I

2007
Residual platelet activity is increased in clopidogrel- and ASA-treated patients with coronary stenting for acute coronary syndromes compared with stable coronary artery disease.
    Heart (British Cardiac Society), 2008, Volume: 94, Issue:6

    Topics: Acute Coronary Syndrome; Aged; Aspirin; Clopidogrel; Cohort Studies; Coronary Artery Disease; Coronary Thrombosis; Drug Therapy, Combination; Female; Humans; Male; Platelet Activation; Platelet Aggregation Inhibitors; Prospective Studies; Risk Factors; Stents; Ticlopidine; Treatment Outcome

2008
Confined late stent thrombosis following clopidogrel withdrawal in a patient with multi-segment sirolimus-eluting stent implants.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2007, Volume: 8, Issue:7

    Topics: Abciximab; Aged; Angioplasty, Balloon; Antibodies, Monoclonal; Anticoagulants; Clopidogrel; Coronary Artery Disease; Coronary Stenosis; Coronary Thrombosis; Heparin; Humans; Immunoglobulin Fab Fragments; Immunosuppressive Agents; Male; Platelet Aggregation Inhibitors; Sirolimus; Stents; Ticlopidine

2007
Different methodologies for evaluating the effect of clopidogrel on platelet function in high-risk coronary artery disease patients.
    Journal of thrombosis and haemostasis : JTH, 2007, Volume: 5, Issue:9

    Topics: Aged; Blood Platelets; Clopidogrel; Coronary Artery Disease; Female; Flow Cytometry; Humans; Male; Middle Aged; Phosphorylation; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine

2007
Sirolimus-eluting stent thrombosis several years after clopidogrel discontinuation.
    The Journal of invasive cardiology, 2007, Volume: 19, Issue:9

    Topics: Adult; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Coronary Thrombosis; Drug Delivery Systems; Humans; Immunosuppressive Agents; Male; Platelet Aggregation Inhibitors; Sirolimus; Stents; Ticlopidine; Time Factors

2007
Effect of caffeine on platelet inhibition by clopidogrel in healthy subjects and patients with coronary artery disease.
    American heart journal, 2007, Volume: 154, Issue:4

    Topics: Adult; Aged; Caffeine; Clopidogrel; Coronary Artery Disease; Cross-Over Studies; Drug Synergism; Female; Humans; Hydrazones; Male; Middle Aged; P-Selectin; Phosphodiesterase Inhibitors; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Receptor, Adenosine A2A; Ticlopidine

2007
Impact of platelet reactivity on cardiovascular outcomes in patients with type 2 diabetes mellitus and coronary artery disease.
    Journal of the American College of Cardiology, 2007, Oct-16, Volume: 50, Issue:16

    Topics: Aged; Angina, Unstable; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Death, Sudden, Cardiac; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Humans; Male; Multivariate Analysis; Myocardial Infarction; Outcome Assessment, Health Care; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Predictive Value of Tests; Prognosis; Prospective Studies; Renal Insufficiency; ROC Curve; Sensitivity and Specificity; Stroke; Ticlopidine

2007
Sweet and sticky: diabetic platelets, enhanced reactivity, and cardiovascular risk.
    Journal of the American College of Cardiology, 2007, Oct-16, Volume: 50, Issue:16

    Topics: Angina, Unstable; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Death, Sudden, Cardiac; Diabetes Mellitus, Type 2; Humans; Myocardial Infarction; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Prognosis; Stroke; Ticlopidine

2007
The Residual Platelet Aggregation after Deployment of Intracoronary Stent (PREDICT) score.
    Journal of thrombosis and haemostasis : JTH, 2008, Volume: 6, Issue:1

    Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Aged; Angina Pectoris; Clopidogrel; Cohort Studies; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Models, Statistical; Platelet Aggregation; Platelet Function Tests; Regression Analysis; Stents; Ticlopidine

2008
The CAPRIE-like subgroups of CHARISMA: a CAPRIEciously biased analysis of an unCHARISMAtic truth.
    Journal of the American College of Cardiology, 2007, Oct-23, Volume: 50, Issue:17

    Topics: Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Humans; Myocardial Ischemia; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Research Design; Ticlopidine; Treatment Outcome

2007
P2Y12 polymorphisms and antiplatelet effects of aspirin in patients with coronary artery disease.
    British journal of clinical pharmacology, 2008, Volume: 65, Issue:4

    Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Female; Genotype; Haplotypes; Humans; Male; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Ticlopidine; Treatment Outcome

2008
Coronary artery stenting in patients treated by clopidogrel without aspirin.
    International journal of cardiology, 2009, Apr-03, Volume: 133, Issue:2

    Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Risk Factors; Stents; Thrombosis; Ticlopidine

2009
Outcomes associated with combined antiplatelet and anticoagulant therapy.
    Chest, 2008, Volume: 133, Issue:4

    Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Clopidogrel; Cohort Studies; Coronary Artery Disease; Dipyridamole; Drug Therapy, Combination; Female; Hemorrhage; Humans; Longitudinal Studies; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Retrospective Studies; Risk Factors; Thromboembolism; Ticlopidine; Treatment Outcome; Warfarin

2008
Restrictive access to clopidogrel and mortality following coronary stent implantation.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2008, Feb-12, Volume: 178, Issue:4

    Topics: Aged; Canada; Cause of Death; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Coronary Restenosis; Drug Costs; Drug Prescriptions; Female; Follow-Up Studies; Humans; Insurance, Pharmaceutical Services; Male; Middle Aged; Multivariate Analysis; Platelet Aggregation Inhibitors; Retrospective Studies; Stents; Survival Rate; Ticlopidine; Time Factors

2008
How to optimise clopidogrel therapy? Reducing the low-response incidence by aggregometry-guided therapy modification.
    Thrombosis and haemostasis, 2008, Volume: 99, Issue:2

    Topics: Adenosine Diphosphate; Aged; Algorithms; Angioplasty, Balloon, Coronary; Aspirin; Blood Platelets; Cardiovascular Diseases; Clinical Protocols; Clopidogrel; Coronary Artery Disease; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Monitoring; Drug Resistance; Feasibility Studies; Female; Humans; Male; Middle Aged; Pilot Projects; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Stents; Ticlopidine

2008
Rapid oral aspirin desensitization for patients with aspirin allergy requiring dual antiplatelet therapy.
    Connecticut medicine, 2008, Volume: 72, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Hypersensitivity; Drug Therapy, Combination; Humans; Inactivation, Metabolic; Membrane Proteins; Platelet Aggregation Inhibitors; Receptors, Leukotriene; Ticlopidine

2008
Clinical outcomes after multilesion percutaneous coronary intervention: comparison between exclusive and selective use of drug-eluting stents.
    The Journal of invasive cardiology, 2008, Volume: 20, Issue:3

    Topics: Aged; Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Artery Disease; Coronary Restenosis; Coronary Thrombosis; Drug-Eluting Stents; Female; Follow-Up Studies; Health Care Costs; Humans; Male; Middle Aged; Patient Selection; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Quebec; Retrospective Studies; Stents; Ticlopidine; Treatment Outcome

2008
Drug-eluting versus bare-metal stents: when and for whom?
    The Journal of invasive cardiology, 2008, Volume: 20, Issue:3

    Topics: Angioplasty, Balloon, Coronary; Canada; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Diabetes Complications; Drug-Eluting Stents; Health Care Costs; Humans; Patient Selection; Platelet Aggregation Inhibitors; Stents; Ticlopidine

2008
Effects of diabetes mellitus on platelet reactivity after dual antiplatelet therapy with aspirin and clopidogrel.
    Thrombosis and haemostasis, 2008, Volume: 99, Issue:3

    Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Cohort Studies; Coronary Artery Disease; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Humans; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Thrombosis; Ticlopidine; Treatment Outcome

2008
Unilateral idiopathic adrenal hematomas with a preoperative diagnosis of indeterminate adrenal tumors.
    Journal of endourology, 2008, Volume: 22, Issue:5

    Topics: Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenalectomy; Aged; Anemia; Aspirin; Clopidogrel; Coronary Artery Disease; Diagnosis, Differential; Female; Hematoma; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Preoperative Care; Retrospective Studies; Stents; Ticlopidine

2008
Acute stent thrombosis in a patient with giant cell arteritis.
    The Canadian journal of cardiology, 2008, Volume: 24, Issue:4

    Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Coronary Thrombosis; Giant Cell Arteritis; Humans; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Prednisone; Stents; Ticlopidine

2008
Innovations in bifurcations.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2008, May-01, Volume: 71, Issue:6

    Topics: Angioplasty, Balloon, Coronary; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Humans; Patient Selection; Platelet Aggregation Inhibitors; Prosthesis Design; Research Design; Severity of Illness Index; Stents; Ticlopidine; Treatment Outcome; Ultrasonography, Interventional

2008
Glycoprotein IIb/IIIa receptor inhibition with abciximab during percutaneous coronary interventions increases the risk of bleeding in patients with impaired renal function.
    Cardiology, 2008, Volume: 111, Issue:4

    Topics: Abciximab; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Female; Germany; Glomerular Filtration Rate; Hemorrhage; Humans; Immunoglobulin Fab Fragments; Male; Middle Aged; Multivariate Analysis; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Renal Insufficiency; Retrospective Studies; Surveys and Questionnaires; Survival Analysis; Ticlopidine

2008
Clopidogrel instead of ticlopidine after coronary stent placement: is the switch justified?
    American heart journal, 2000, Volume: 140, Issue:3

    Topics: Clopidogrel; Coronary Artery Disease; Humans; Platelet Aggregation Inhibitors; Postoperative Complications; Stents; Thrombosis; Ticlopidine

2000
Clopidogrel for prevention of major cardiac events after coronary stent implantation: 30-day and 6-month results in patients with smaller stents.
    American heart journal, 2000, Volume: 140, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Disease; Cost-Benefit Analysis; Drug Costs; Equipment Design; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Postoperative Complications; Prospective Studies; Registries; Stents; Ticlopidine

2000
Bench to bedside: the development of rapamycin and its application to stent restenosis.
    Circulation, 2001, Aug-21, Volume: 104, Issue:8

    Topics: Angioplasty, Balloon, Coronary; Animals; Calcineurin Inhibitors; Carrier Proteins; Cell Cycle Proteins; Cell Division; Cell Movement; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Cyclin-Dependent Kinase Inhibitor p27; Down-Regulation; Graft Occlusion, Vascular; Humans; Hyperplasia; Macromolecular Substances; Phosphotransferases (Alcohol Group Acceptor); Platelet Aggregation Inhibitors; Signal Transduction; Sirolimus; Stents; Tacrolimus; Tacrolimus Binding Protein 1A; Ticlopidine; TOR Serine-Threonine Kinases; Tumor Suppressor Proteins; Tunica Media; Vascular Patency

2001
Coronary stent deployment in situs inversus.
    Heart (British Cardiac Society), 2001, Volume: 86, Issue:5

    Topics: Aged; Aspirin; Chest Pain; Clopidogrel; Coronary Artery Disease; Dextrocardia; Electrocardiography; Humans; Male; Situs Inversus; Stents; Ticlopidine

2001
Same-day transradial outpatient stenting with a 6-hr course of glycoprotein IIb/IIIa receptor blockade: a feasibility study.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2002, Volume: 56, Issue:1

    Topics: Adult; Aged; Ambulatory Surgical Procedures; Angioplasty, Balloon, Coronary; Aspirin; Blood Vessel Prosthesis Implantation; Clopidogrel; Coronary Artery Disease; Coronary Vessels; Creatine Kinase; Electrocardiography; Feasibility Studies; Female; Follow-Up Studies; Humans; Length of Stay; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Stents; Stroke Volume; Ticlopidine; Time Factors; Treatment Outcome

2002
[Two platelet inhibitors after acute coronary syndrome. Many colleagues are not aware of this].
    MMW Fortschritte der Medizin, 2002, Mar-28, Volume: 144, Issue:13

    Topics: Aspirin; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Survival Rate; Ticlopidine

2002