clopidogrel and Body Weight

clopidogrel has been researched along with Body Weight in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (28.00)29.6817
2010's13 (52.00)24.3611
2020's5 (20.00)2.80

Authors

AuthorsStudies
Cheng, J; Deng, X; Li, H; Ma, Y; Shi, T; Wang, X; Wu, Y; Zhang, Z; Zhu, Q1
Abdolhoseini, M; Hinwood, M; Hood, RJ; Johnson, SJ; Martin, K; Nilsson, M; Paul, JW; Paul, M; Pollack, M; Walker, FR1
Abe, K; Ikeda, Y; Kitagawa, K; Kitazono, T; Nanto, S; Nishikawa, M; Ogawa, A; Toyoda, K1
Atar, S; Bernaud, C; Fahrni, G; Frenoux, JM; Hmissi, A; Moccetti, T; Mueller, C; Schelfaut, D; Sinnaeve, P; Spirito, A; Ufer, M; Valgimigli, M1
Dong, W; He, X; Hu, H; Kong, Y; Li, Y; Li, Z; Sun, L; Wang, C; Wang, Y; Yang, D; Zhang, J; Zhao, M1
Court, MH; Faus, MCL; Lee, PM1
Angiolillo, DJ; Bergmeijer, TO; Brown, P; Erlinge, D; Jakubowski, JA; James, S; Moser, BA; Small, DS; Ten Berg, JM; Wagner, H; Winters, KJ; Zhou, C1
Angiolillo, DJ; Brown, PB; Erlinge, D; Jakubowski, JA; James, S; Moser, BA; Small, DS; Ten Berg, JM; Winters, KJ; Zhou, C1
Vengoechea, F1
Bode, C; Diehl, P; Moser, M; Olivier, CB; Schnabel, K; Weber, S; Zhou, Q1
Al-Zumyli, R; Arafat, T; Bulatova, NR; Yousef, AM1
Beckerman, P; Ben-Artzi, M; Ben-Yehuda, A; Haber, G; Levin, A; Muszkat, M; Varon, D1
Antonino, MJ; Gurbel, PA; Tantry, US1
Aleil, B; Cazenave, JP; Gachet, C; Léon, C1
Hirata, K; Momose, A; Nakajima, K; Sasaki, N; Shinohara, M; Takeda, M; Tawa, H; Yamashita, T1
Alexander, MJ; Choulakian, A; Drazin, D; Kornbluth, P; Nuño, M1
Ahmed, N; Egido, JA; Ford, GA; Lees, KR; Mazya, M; Mikulik, R; Toni, D; Wahlgren, N1
Crimizade, U; El Ghannudi, S; Gachet, C; Hess, S; Jesel, L; Morel, O; Ohlmann, P; Radulescu, B; Reydel, A; Wiesel, ML1
Minematsu, K; Tanahashi, N; Uchiyama, S1
Angiolillo, DJ; Bergmeijer, T; Brown, PB; Erlinge, D; Foley, D; Jakubowski, JA; James, S; Luo, J; Moser, B; Small, DS; Ten Berg, J; Wagner, H; Winters, KJ; Zhou, C1
Armstrong, PW; Brown, E; Chan, MY; Cornel, JH; Erlinge, D; Fox, KA; Goodman, SG; Gurbel, PA; Huber, K; Jakubowski, JA; Neely, B; Neely, M; Ohman, EM; Prabhakaran, D; Roe, MT; Tantry, US; White, HD; Zhou, C1
Abrams, J; Berra, K; Blankenship, JC; Dallas, AP; Douglas, PS; Fihn, SD; Foody, JM; Gardin, JM; Gerber, TC; Hinderliter, AL; King, SB; Kligfield, PD; Krumholz, HM; Kwong, RY; Lim, MJ; Linderbaum, JA; Mack, MJ; Munger, MA; Prager, RL; Sabik, JF; Shaw, LJ; Sikkema, JD; Smith, CR; Smith, SC; Spertus, JA; Williams, SV1
Alfonso, F; Angiolillo, DJ; Barrera Ramírez, C; Bernardo, E; Escaned, J; Fernandez, C; Fernández-Ortiz, A; Hernández-Antolín, R; Macaya, C; Sabaté, M1
Patel, MR; Peterson, ED1
Goodall, AH; Hayes, PD; Jones, CI; Naylor, AR; Payne, DA1

Reviews

2 review(s) available for clopidogrel and Body Weight

ArticleYear
Management of acute coronary syndrome in the hospital: a focus on ACCF/AHA guideline updates to oral antiplatelet therapy.
    Hospital practice (1995), 2014, Volume: 42, Issue:3

    Topics: Acute Coronary Syndrome; Adenosine; Age Factors; Aspirin; Body Weight; Clopidogrel; Humans; Myocardial Infarction; Piperazines; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Prasugrel Hydrochloride; Quality of Health Care; Randomized Controlled Trials as Topic; Thiophenes; Ticagrelor; Ticlopidine

2014
Recent developments in clopidogrel pharmacology and their relation to clinical outcomes.
    Expert opinion on drug metabolism & toxicology, 2009, Volume: 5, Issue:8

    Topics: Animals; Body Weight; Cardiovascular Diseases; Clopidogrel; Cytochrome P-450 Enzyme System; Humans; Pharmacogenetics; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2Y12; Ticlopidine; Treatment Outcome

2009

Trials

8 trial(s) available for clopidogrel and Body Weight

ArticleYear
Safety and Efficacy of Prasugrel in Elderly/Low Body Weight Japanese Patients with Ischemic Stroke: Randomized PRASTRO-II.
    Cerebrovascular diseases (Basel, Switzerland), 2020, Volume: 49, Issue:2

    Topics: Age Factors; Aged; Aged, 80 and over; Asian People; Body Weight; Brain Ischemia; Clopidogrel; Double-Blind Method; Female; Health Status; Hemorrhage; Humans; Incidence; Japan; Male; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Recurrence; Risk Assessment; Risk Factors; Stroke; Time Factors; Treatment Outcome

2020
Subcutaneous Selatogrel Inhibits Platelet Aggregation in Patients With Acute Myocardial Infarction.
    Journal of the American College of Cardiology, 2020, 05-26, Volume: 75, Issue:20

    Topics: Adult; Aged; Aged, 80 and over; Body Weight; Clopidogrel; Drug Therapy, Combination; Female; Humans; Injections, Subcutaneous; Male; Middle Aged; Myocardial Infarction; Organophosphonates; Patient Safety; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Pyrimidines; Ticagrelor; Treatment Outcome

2020
Higher body weight patients on clopidogrel maintenance therapy have lower active metabolite concentrations, lower levels of platelet inhibition, and higher rates of poor responders than low body weight patients.
    Journal of thrombosis and thrombolysis, 2014, Volume: 38, Issue:2

    Topics: Adolescent; Adult; Aged; Blood Platelets; Body Weight; Clopidogrel; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticlopidine

2014
Smoking behaviour modulates pharmacokinetics of orally administered clopidogrel.
    Journal of clinical pharmacy and therapeutics, 2008, Volume: 33, Issue:4

    Topics: Administration, Oral; Adult; Area Under Curve; Body Weight; Clopidogrel; Drug Interactions; Half-Life; Humans; Male; Platelet Aggregation Inhibitors; Smoking; Ticlopidine

2008
Predicting the risk of symptomatic intracerebral hemorrhage in ischemic stroke treated with intravenous alteplase: safe Implementation of Treatments in Stroke (SITS) symptomatic intracerebral hemorrhage risk score.
    Stroke, 2012, Volume: 43, Issue:6

    Topics: Age Factors; Aged; Aspirin; Body Weight; Brain Ischemia; Cerebral Hemorrhage; Clopidogrel; Female; Fibrinolytic Agents; Humans; Hypertension; Injections, Intravenous; Logistic Models; Male; Middle Aged; Platelet Aggregation Inhibitors; Predictive Value of Tests; Registries; Risk Factors; Stroke; Ticlopidine; Tissue Plasminogen Activator

2012
Clopidogrel two doses comparative 1-year assessment of safety and efficacy (COMPASS) study in Japanese patients with ischemic stroke.
    Cerebrovascular diseases (Basel, Switzerland), 2012, Volume: 34, Issue:3

    Topics: Age Factors; Aged; Asian People; Body Weight; Clopidogrel; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Hemorrhage; Humans; Incidence; Japan; Longitudinal Studies; Male; Middle Aged; Myocardial Infarction; Peripheral Arterial Disease; Platelet Aggregation Inhibitors; Risk Factors; Secondary Prevention; Stroke; Ticlopidine; Treatment Outcome

2012
Platelet function during extended prasugrel and clopidogrel therapy for patients with ACS treated without revascularization: the TRILOGY ACS platelet function substudy.
    JAMA, 2012, Nov-07, Volume: 308, Issue:17

    Topics: Acute Coronary Syndrome; Age Factors; Aged; Angina, Unstable; Aspirin; Body Weight; Clopidogrel; Female; Humans; Male; Myocardial Infarction; Myocardial Ischemia; Piperazines; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Stroke; Thiophenes; Ticlopidine; Treatment Outcome

2012
Therapeutic benefit of low-dose clopidogrel in patients undergoing carotid surgery is linked to variability in the platelet adenosine diphosphate response and patients' weight.
    Stroke, 2007, Volume: 38, Issue:9

    Topics: Adenosine Diphosphate; Aspirin; Blood Platelets; Body Weight; Clopidogrel; Endarterectomy, Carotid; Humans; Placebos; Platelet Activation; Platelet Aggregation Inhibitors; Postoperative Complications; Statistics as Topic; Thrombosis; Ticlopidine

2007

Other Studies

15 other study(ies) available for clopidogrel and Body Weight

ArticleYear
Effect of body weight on bleeding events of aspirin in ischemic stroke or transient ischemic attack patients.
    Journal of clinical pharmacy and therapeutics, 2022, Volume: 47, Issue:10

    Topics: Aspirin; Body Weight; Clopidogrel; Drug Therapy, Combination; Hemorrhage; Humans; Ischemic Attack, Transient; Ischemic Stroke; Platelet Aggregation Inhibitors; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Stroke; Ticlopidine; Treatment Outcome

2022
Clopidogrel Administration Impairs Post-Stroke Learning and Memory Recovery in Mice.
    International journal of molecular sciences, 2023, Jul-20, Volume: 24, Issue:14

    Topics: Body Weight; Clopidogrel; Cognition; Humans; Male; Platelet Aggregation Inhibitors; Stroke

2023
Body weight, CYP2C19, and P2Y12 receptor polymorphisms relate to clopidogrel resistance in a cohort of Chinese ischemic stroke patients with aspirin intolerance.
    European journal of clinical pharmacology, 2020, Volume: 76, Issue:11

    Topics: Aged; Aspirin; Body Weight; Clopidogrel; Cohort Studies; Cytochrome P-450 CYP2C19; Drug Resistance; Female; Genotype; Humans; Ischemic Stroke; Male; Middle Aged; Polymorphism, Single Nucleotide; Receptors, Purinergic P2Y12

2020
High interindividual variability in plasma clopidogrel active metabolite concentrations in healthy cats is associated with sex and cytochrome P450 2C genetic polymorphism.
    Journal of veterinary pharmacology and therapeutics, 2019, Volume: 42, Issue:1

    Topics: Animals; Body Weight; Cats; Chromatography, High Pressure Liquid; Clopidogrel; Cytochrome P-450 Enzyme System; Female; Genotyping Techniques; Male; Polymorphism, Genetic; Sex Factors; Tandem Mass Spectrometry

2019
The influence of body size on the pharmacodynamic and pharmacokinetic response to clopidogrel and prasugrel: a retrospective analysis of the FEATHER study.
    Thrombosis research, 2014, Volume: 134, Issue:3

    Topics: Adult; Aged; Biomarkers; Blood Platelets; Body Mass Index; Body Size; Body Surface Area; Body Weight; Cell Adhesion Molecules; Clopidogrel; Coronary Artery Disease; Drug Dosage Calculations; Female; Humans; Male; Microfilament Proteins; Middle Aged; Phosphoproteins; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Randomized Controlled Trials as Topic; Receptors, Purinergic P2Y12; Retrospective Studies; Ticlopidine; Treatment Outcome

2014
Platelet reactivity after administration of third generation P2Y12-antagonists does not depend on body weight in contrast to clopidogrel.
    Journal of thrombosis and thrombolysis, 2016, Volume: 42, Issue:1

    Topics: Adenosine; Body Weight; Clopidogrel; Dose-Response Relationship, Drug; Drug Dosage Calculations; Humans; Platelet Activation; Platelet Aggregation; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Ticagrelor; Ticlopidine

2016
Factors associated with bleeding in elderly hospitalized patients treated with enoxaparin sodium : a prospective, open-label, observational study.
    Drugs & aging, 2009, Volume: 26, Issue:1

    Topics: Aged; Aged, 80 and over; Anticoagulants; Body Weight; Clopidogrel; Creatinine; Dose-Response Relationship, Drug; Enoxaparin; Factor Xa Inhibitors; Female; Hemorrhage; Humans; Inpatients; Length of Stay; Logistic Models; Male; Middle Aged; Odds Ratio; Prospective Studies; Risk Factors; Sex Factors; Ticlopidine; Treatment Outcome; Warfarin

2009
CYP2C19*2 polymorphism is not the sole determinant of the response to clopidogrel: implications for its monitoring.
    Journal of thrombosis and haemostasis : JTH, 2009, Volume: 7, Issue:10

    Topics: Aged; Aryl Hydrocarbon Hydroxylases; Body Weight; Clopidogrel; Comorbidity; Cytochrome P-450 CYP2C19; Drug Interactions; Drug Monitoring; Female; Genotype; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Polypharmacy; Smoking; Ticlopidine; Vasodilator Agents

2009
Beneficial effect of anti-platelet therapies on atherosclerotic lesion formation assessed by phase-contrast X-ray CT imaging.
    The international journal of cardiovascular imaging, 2012, Volume: 28, Issue:5

    Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; Body Weight; Brachiocephalic Trunk; Cell Adhesion Molecules; Cholesterol, Dietary; Cilostazol; Clopidogrel; Collagen; Cytokines; Disease Models, Animal; Gene Expression Regulation; Immunohistochemistry; Inflammation Mediators; Lipids; Macrophages; Mice; Mice, Knockout; Plaque, Atherosclerotic; Platelet Aggregation Inhibitors; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazoles; Ticlopidine; Tomography, X-Ray Computed

2012
Body weight: a risk factor for subtherapeutic antithrombotic therapy in neurovascular stenting.
    Journal of neurointerventional surgery, 2011, Volume: 3, Issue:2

    Topics: Aspirin; Body Mass Index; Body Weight; Carotid Stenosis; Cerebrovascular Disorders; Clopidogrel; Female; Fibrinolytic Agents; Humans; Intracranial Aneurysm; Male; Middle Aged; Retrospective Studies; Risk Factors; Stents; Thrombolytic Therapy; Ticlopidine; Treatment Failure

2011
The extent of P2Y12 inhibition by clopidogrel in diabetes mellitus patients with acute coronary syndrome is not related to glycaemic control: roles of white blood cell count and body weight.
    Thrombosis and haemostasis, 2012, Volume: 108, Issue:2

    Topics: Acute Coronary Syndrome; Aged; Body Weight; Clopidogrel; Diabetes Complications; Diabetes Mellitus; Female; Flow Cytometry; Glycated Hemoglobin; Humans; Inflammation; Leukocyte Count; Leukocytes; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Percutaneous Coronary Intervention; Phosphorylation; Proportional Hazards Models; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Ticlopidine

2012
Reduction in platelet reactivity with prasugrel 5 mg in low-body-weight patients is noninferior to prasugrel 10 mg in higher-body-weight patients: results from the FEATHER trial.
    Journal of the American College of Cardiology, 2012, Nov-13, Volume: 60, Issue:20

    Topics: Adolescent; Adult; Aged; Blood Platelets; Body Weight; Clopidogrel; Coronary Artery Disease; Cross-Over Studies; Female; Humans; Male; Middle Aged; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Single-Blind Method; Thiophenes; Ticlopidine; Young Adult

2012
2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS Guideline for the diagnosis and management of patients with stable ischemic heart disease: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, and the
    Journal of the American College of Cardiology, 2012, Dec-18, Volume: 60, Issue:24

    Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Alcohol Drinking; Angina Pectoris; Body Weight; Cholesterol, LDL; Clopidogrel; Comorbidity; Cost of Illness; Depression; Diabetes Complications; Disease Management; Electrocardiography; Exercise; Exercise Test; Glycated Hemoglobin; Health Behavior; Humans; Hypertension; Life Style; Myocardial Infarction; Myocardial Ischemia; Myocardial Revascularization; Physical Examination; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Quality of Life; Risk Assessment; Risk Factors; Risk Reduction Behavior; Smoking Cessation; Ticlopidine

2012
Platelet aggregation according to body mass index in patients undergoing coronary stenting: should clopidogrel loading-dose be weight adjusted?
    The Journal of invasive cardiology, 2004, Volume: 16, Issue:4

    Topics: Aged; Blood Vessel Prosthesis Implantation; Body Mass Index; Body Weight; Clopidogrel; Coronary Stenosis; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Spain; Stents; Ticlopidine; Treatment Outcome; Weights and Measures

2004
Clopidogrel dosing in overweight patients: does one size fit all?
    The Journal of invasive cardiology, 2004, Volume: 16, Issue:4

    Topics: Blood Vessel Prosthesis Implantation; Body Mass Index; Body Weight; Clopidogrel; Coronary Stenosis; Dose-Response Relationship, Drug; Humans; Obesity; Platelet Aggregation; Platelet Aggregation Inhibitors; Stents; Ticlopidine

2004