Compounds > clopidogrel

clopidogrel and Acute Liver Injury, Drug-Induced

clopidogrel has been researched along with Acute Liver Injury, Drug-Induced in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (4.00)18.2507
2000's9 (36.00)29.6817
2010's14 (56.00)24.3611
2020's1 (4.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ding, D; Fang, H; Kelly, R; Liu, Z; Shi, Q; Tong, W1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bektasoglu, G; Dogan, Z; Yurtdas, M1
Deguchi, S; Harada, K; Hirata, K; Igai, K; Mizuguchi, H; Takayama, K; Toba, Y; Yamashita, T1
Can, MM; Dinicolantonio, JJ; Kuliczkowski, W; Pershukov, IV; Serebruany, VL1
Baek, YH; Cho, DS; Chung, WT; Han, SY; Kang, SH; Lee, SW; Park, IC1
Chhabra, L; Kapila, A; Khanna, A; Locke, AD; Patel, P; Reddy, CM; Young, MF1
An, L; Cui, T; Feng, G; Feng, S; He, X; Wang, L; Yang, F; Zhai, Y1
Arteaga, M; Etxeberria-Lekuona, D; Jarne, V; Méndez-López, I; Mercado, MR; Oteiza, J1
Joshi, N; Kopec, AK; Luyendyk, JP; Ray, JL1
Goyal, RK; Lessnau, KD; Srivastava, D1
Blombery, PA; Daffy, JR; Russell, PA1
ben Abdallah, H; Daghfous, R; El Aïdli, S; Kastalli, S; Zaïem, A1
Anselmino, M; Moretti, C; Ravera, L; Sheiban, I1
Gordon, C; Leighton, SP; Shand, A1
Darwish, OS; Iqbal, E1
Calvo Carrasco, L; García Díaz, Jde D; Ramos Ramos, JC; Sanz Moreno, J1
Beltran-Robles, M; Marquez Saavedra, E; Romero-Gomez, M; Sanchez-Muñoz, D1
Chan, WK; Chau, TN; Lai, ST; Leung, MF; Leung, VK; Mok, NS; Yim, KF1
Graziadei, I; Höllmüller, I; Stadlmann, S; Vogel, W1
Goldberg, N; Ng, JA; Tafreshi, MJ1
Garfia, C; López-Medrano, F; López-Vicente, J; Yela, C1
Carson, JJ; Zeolla, MM1
Durán Quintana, JA; Gutiérrez, MH; Jiménez Sáenz, M; Montero, AR1

Reviews

4 review(s) available for clopidogrel and Acute Liver Injury, Drug-Induced

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Cholestasic toxic hepatitis due to clopidogrel in a patient with multiple conditions].
    Anales del sistema sanitario de Navarra, 2016, 04-29, Volume: 39, Issue:1

    Topics: Chemical and Drug Induced Liver Injury; Clopidogrel; Coronary Artery Disease; Humans; Platelet Aggregation Inhibitors; Ticlopidine

2016
Clopidogrel-induced hepatocellular injury and cholestatic jaundice in an elderly patient: case report and review of the literature.
    Pharmacotherapy, 2009, Volume: 29, Issue:5

    Topics: Aged; Angioplasty, Balloon, Coronary; Chemical and Drug Induced Liver Injury; Clinical Enzyme Tests; Clopidogrel; Female; Humans; Jaundice, Obstructive; Liver Diseases; Platelet Aggregation Inhibitors; Ticlopidine

2009
Clinico-histopathological characteristics of clopidogrel-induced hepatic injury: case report and review of literature.
    European journal of gastroenterology & hepatology, 2006, Volume: 18, Issue:8

    Topics: Aged, 80 and over; Chemical and Drug Induced Liver Injury; Clopidogrel; Humans; Male; Platelet Aggregation Inhibitors; Ticlopidine

2006

Other Studies

21 other study(ies) available for clopidogrel and Acute Liver Injury, Drug-Induced

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Databases, Factual; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Models, Biological; Predictive Value of Tests

2011
Prasugrel-related hepatotoxicity.
    JPMA. The Journal of the Pakistan Medical Association, 2022, Volume: 72, Issue:11

    Topics: Acute Coronary Syndrome; Chemical and Drug Induced Liver Injury; Clopidogrel; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Ticagrelor; Treatment Outcome

2022
Modeling of Hepatic Drug Metabolism and Responses in CYP2C19 Poor Metabolizer Using Genetically Manipulated Human iPS cells.
    Drug metabolism and disposition: the biological fate of chemicals, 2019, Volume: 47, Issue:6

    Topics: Cell Differentiation; Cell Line; Cell Survival; Chemical and Drug Induced Liver Injury; Clopidogrel; Cytochrome P-450 CYP2C19; Hepatocytes; Humans; Induced Pluripotent Stem Cells; Ketoconazole; Liver; Metabolic Clearance Rate

2019
Gastrointestinal adverse events after dual antiplatelet therapy: clopidogrel is safer than ticagrelor, but prasugrel data are lacking or inconclusive.
    Cardiology, 2013, Volume: 126, Issue:1

    Topics: Acute Coronary Syndrome; Adenosine; Aspirin; Chemical and Drug Induced Liver Injury; Clinical Trials, Phase III as Topic; Clopidogrel; Double-Blind Method; Female; Gastrointestinal Hemorrhage; Gastrointestinal Neoplasms; Humans; Kaplan-Meier Estimate; Male; Multicenter Studies as Topic; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Randomized Controlled Trials as Topic; Risk Factors; Thiophenes; Ticagrelor; Ticlopidine

2013
Simultaneous intrahepatic and subgaleal hemorrhage in antiphospholipid syndrome following anticoagulation therapy.
    World journal of gastroenterology, 2013, Oct-14, Volume: 19, Issue:38

    Topics: Adolescent; Anticoagulants; Antiphospholipid Syndrome; Chemical and Drug Induced Liver Injury; Clopidogrel; Drug Substitution; Drug Therapy, Combination; Female; Flank Pain; Hemorrhage; Humans; Hydroxychloroquine; International Normalized Ratio; Magnetic Resonance Imaging; Platelet Aggregation Inhibitors; Recurrence; Risk Factors; Scalp; Skin Diseases; Ticlopidine; Tomography, X-Ray Computed; Treatment Outcome; Venous Thrombosis

2013
An idiosyncratic reaction to clopidogrel.
    The Permanente journal, 2015,Winter, Volume: 19, Issue:1

    Topics: Aged; Chemical and Drug Induced Liver Injury; Clopidogrel; Female; Humans; Platelet Aggregation Inhibitors; Ticlopidine; Vomiting

2015
The mechanism and risk factors of clopidogrel-induced liver injury.
    Drug and chemical toxicology, 2016, Volume: 39, Issue:4

    Topics: Animals; Chemical and Drug Induced Liver Injury; Clopidogrel; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2C19; Hep G2 Cells; Hepatocytes; Humans; Male; Membrane Potential, Mitochondrial; Mice, Inbred Strains; Models, Biological; Platelet Aggregation Inhibitors; Rats, Wistar; Reactive Oxygen Species; Risk Factors; Ticlopidine

2016
Inhibition of PAR-4 and P2Y12 receptor-mediated platelet activation produces distinct hepatic pathologies in experimental xenobiotic-induced cholestatic liver disease.
    Toxicology, 2016, 07-15, Volume: 365

    Topics: 1-Naphthylisothiocyanate; Animals; Chemical and Drug Induced Liver Injury; Cholestasis; Clopidogrel; Liver; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Platelet Activation; Purinergic P2Y Receptor Antagonists; Receptors, Proteinase-Activated; Serotonin; Ticlopidine; Xenobiotics

2016
An unusual case of recurrent fever, jaundice and right upper quadrant pain.
    The Medical journal of Australia, 2009, Oct-05, Volume: 191, Issue:7

    Topics: Abdominal Pain; Aged; Chemical and Drug Induced Liver Injury; Clopidogrel; Fever; Humans; Jaundice; Liver; Male; Platelet Aggregation Inhibitors; Ticlopidine

2009
Fatal liver injury associated with clopidogrel.
    Fundamental & clinical pharmacology, 2010, Volume: 24, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Clopidogrel; Fatal Outcome; Humans; Liver Function Tests; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine

2010
Clopidogrel treatment in a patient with ticlopidine-induced hepatitis following percutaneous coronary stenting.
    Minerva cardioangiologica, 2010, Volume: 58, Issue:2

    Topics: Aged, 80 and over; Angioplasty, Balloon, Coronary; Chemical and Drug Induced Liver Injury; Clopidogrel; Female; Humans; Platelet Aggregation Inhibitors; Postoperative Complications; Stents; Ticlopidine

2010
Clopidogrel, Turkey and a red herring?
    BMJ case reports, 2011, Apr-09, Volume: 2011

    Topics: Chemical and Drug Induced Liver Injury; Clopidogrel; Diagnosis, Differential; Hepatitis E; Humans; Male; Middle Aged; Ticlopidine; Travel; Turkey

2011
Dual antiplatelet agent-induced spontaneous liver hematoma.
    The Annals of pharmacotherapy, 2012, Volume: 46, Issue:11

    Topics: Aged; Aspirin; Chemical and Drug Induced Liver Injury; Clopidogrel; Coronary Artery Disease; Drug Therapy, Combination; Hematoma; Humans; Male; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Ticlopidine

2012
[Clopidogrel-induced hepatotoxicity].
    Medicina clinica, 2003, Feb-08, Volume: 120, Issue:4

    Topics: Aged; Aged, 80 and over; Chemical and Drug Induced Liver Injury; Clopidogrel; Female; Humans; Liver Function Tests; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome

2003
Hepatotoxicity induced by clopidogrel.
    Journal of hepatology, 2004, Volume: 40, Issue:3

    Topics: Chemical and Drug Induced Liver Injury; Clopidogrel; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine

2004
Clopidogrel-induced hepatotoxicity after percutaneous coronary stenting.
    Hong Kong medical journal = Xianggang yi xue za zhi, 2005, Volume: 11, Issue:5

    Topics: Aged; Chemical and Drug Induced Liver Injury; Clopidogrel; Combined Modality Therapy; Coronary Disease; Humans; Male; Platelet Aggregation Inhibitors; Stents; Ticlopidine

2005
Clopidogrel-induced hepatotoxicity and fever.
    Pharmacotherapy, 2006, Volume: 26, Issue:7

    Topics: Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Clopidogrel; Female; Fever; Humans; Liver Function Tests; Middle Aged; Platelet Aggregation Inhibitors; Ticlopidine

2006
[Hepatic toxicity and clopidogrel-induced systemic inflammatory response syndrome].
    Revista espanola de cardiologia, 2007, Volume: 60, Issue:3

    Topics: Chemical and Drug Induced Liver Injury; Clopidogrel; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Systemic Inflammatory Response Syndrome; Ticlopidine

2007
Successful use of clopidogrel for cerebrovascular accident in a patient with suspected ticlopidine-induced hepatotoxicity.
    The Annals of pharmacotherapy, 1999, Volume: 33, Issue:9

    Topics: Aged; Cerebrovascular Disorders; Chemical and Drug Induced Liver Injury; Clopidogrel; Female; Humans; Liver Diseases; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome

1999
[Clopidogrel probably induced hepatic toxicity].
    Medicina clinica, 2002, Jun-08, Volume: 119, Issue:1

    Topics: Aged; Chemical and Drug Induced Liver Injury; Clopidogrel; Humans; Male; Platelet Aggregation Inhibitors; Ticlopidine

2002