Page last updated: 2024-08-23

clonixin and Innate Inflammatory Response

clonixin has been researched along with Innate Inflammatory Response in 27 studies

Research

Studies (27)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (14.81)	18.7374
1990's	8 (29.63)	18.2507
2000's	1 (3.70)	29.6817
2010's	11 (40.74)	24.3611
2020's	3 (11.11)	2.80

Authors

Authors	Studies
Edwards, BS; Graves, SW; Saunders, MJ; Sklar, LA; Zhu, J	1
Greene, JM; Martinez, MN	1
Bruckmaier, RM; Sintes, GF; Wellnitz, O	1
Arthur, RM; Goldin, S; Gretler, SR; Kass, PH; Knych, HK; McKemie, DS	1
Catala, M; Fournier, R; Roy, O; Thiry, J	1
Fosse, TK; Levionnois, OL; Ranheim, B	1
Johns, IC; Knowles, EJ; Linnenkohl, W; Mair, TS; Naylor, RJ; Taylor, AH; Wilford, S	1
Freeman, DE	1
Johns, I; Knowles, E; Linnenkohl, W; Mair, T; Naylor, R; Taylor, A; Wilford, S	1
Baynes, RE; Dutko, T; Gehring, R; Herges, G; Li, M; Riviere, JE; Schroeder, JW; Shelver, WL; Smith, DJ; Tell, L	1
Schneider, MJ; Shelver, WL; Smith, DJ	1
Chiesa, OA; Deaver, C; Esparza, J; Jones, YL; Kenyon, E; Lancaster, V; Myers, MJ; Peters, SM; Screven, R; Stubbs, JT; Wiesenfeld, PL; Yancy, H; Yang, M	1
Jeremejeva, J; Kask, K; Orro, T; Waldmann, A	1
Cook, VL; Gandy, JC; Hauptman, JG; Holcombe, SJ; Jacobs, CC; Sordillo, LM	1
Bryant, CE; Farnfield, BA; Janicke, HJ	1
Higgins, AJ; Lees, P	1
Snow, D	1
Cunningham, FM; Landoni, MF; Lees, P	1
Dalle, S; Daval, S; Espinasse, J; Garcia, J; Salat, O; Schelcher, F; Thouvenot, JP; Valarcher, JF	1
Landoni, MF; Lees, P	1
Magnusson, U; Odensvik, K	1
Headley, PM; Herrero, JF	1
Cheng, Z; Lees, P; McKellar, Q; Nolan, A	1
Cheng, Z; McKellar, QA; Nolan, AM	1
Cheng, Z; McKeller, Q; Nolan, A	1
Higgins, AJ; Lees, P; Sharma, SC; Taylor, JB	1
Krohne, SD; Vestre, WA	1

Trials

4 trial(s) available for clonixin and Innate Inflammatory Response

Article	Year
PK/PD modeling of flunixin meglumine in a kaolin-induced inflammation model in piglets. Journal of veterinary pharmacology and therapeutics, 2018, Volume: 41, Issue:2 Topics: Analgesics; Animals; Animals, Newborn; Anti-Inflammatory Agents; Clonixin; Disease Models, Animal; Dose-Response Relationship, Drug; Inflammation; Injections, Intravenous; Kaolin; Pain Measurement; Swine	2018
Comparison of flunixin meglumine and meloxicam for post operative management of horses with strangulating small intestinal lesions. Equine veterinary journal, 2014, Volume: 46, Issue:4 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Clonixin; Endotoxins; Female; Horse Diseases; Horses; Inflammation; Intestinal Obstruction; Intestine, Small; Male; Meloxicam; Postoperative Complications; Thiazines; Thiazoles	2014
Treatment of dairy cows with PGF2α or NSAID, in combination with antibiotics, in cases of postpartum uterine inflammation. Acta veterinaria Scandinavica, 2012, Aug-10, Volume: 54 Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Cattle Diseases; Cephalosporins; Clonixin; Dairying; Dinoprost; Drug Combinations; Endometritis; Estonia; Female; Fertility; Inflammation; Postpartum Period; Puerperal Infection	2012
Effect of oral administration of flunixin meglumine on the inflammatory response to endotoxin in heifers. American journal of veterinary research, 1996, Volume: 57, Issue:2 Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Cattle; Cattle Diseases; Clonixin; Dinoprost; Endotoxins; Escherichia coli; Female; Hydrocortisone; Inflammation; Injections, Intravenous; Leukocyte Count; Leukocytes, Mononuclear; Neutrophils	1996

Other Studies

23 other study(ies) available for clonixin and Innate Inflammatory Response

Article	Year
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. Current protocols in cytometry, 2010, Volume: Chapter 13 Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Proteins; High-Throughput Screening Assays; Humans; Inflammation; Kinetics; Microspheres; Peptide Hydrolases; Peptides; Reproducibility of Results; Temperature	2010
Using simulations to explore the potential effect of disease and inflammation on the frequency of violative flunixin residues in cattle. Journal of veterinary pharmacology and therapeutics, 2023, Volume: 46, Issue:2 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Cattle Diseases; Clonixin; Drug Residues; Inflammation; Liver	2023
Nonsteroidal anti-inflammatory drugs affect the mammary epithelial barrier during inflammation. Journal of dairy science, 2020, Volume: 103, Issue:11 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Cell Count; Clonixin; Cyclooxygenase Inhibitors; Epithelial Cells; Escherichia coli; Female; Inflammation; Ketoprofen; Lipopolysaccharides; Mammary Glands, Animal; Mastitis, Bovine; Meloxicam; Milk; Tumor Necrosis Factor-alpha	2020
Pharmacokinetics of transdermal flunixin meglumine and effects on biomarkers of inflammation in horses. Journal of veterinary pharmacology and therapeutics, 2021, Volume: 44, Issue:5 Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Cattle; Chromatography, Liquid; Clonixin; Horse Diseases; Horses; Inflammation; Tandem Mass Spectrometry	2021
Evaluation of flunixin meglumine pour-on administration on prostaglandin E Research in veterinary science, 2017, Volume: 114 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Cattle Diseases; Clonixin; Dinoprostone; Exudates and Transudates; Inflammation; Random Allocation	2017
Letter to the editor. Equine veterinary journal, 2015, Volume: 47, Issue:2 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Clonixin; Female; Horse Diseases; Inflammation; Male; Postoperative Complications; Thiazines; Thiazoles	2015
Response to letter from Dr Freeman. Equine veterinary journal, 2015, Volume: 47, Issue:2 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Clonixin; Female; Horse Diseases; Inflammation; Male; Postoperative Complications; Thiazines; Thiazoles	2015
Excretory, Secretory, and Tissue Residues after Label and Extra-label Administration of Flunixin Meglumine to Saline- or Lipopolysaccharide-Exposed Dairy Cows. Journal of agricultural and food chemistry, 2015, May-20, Volume: 63, Issue:19 Topics: Adipose Tissue; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Clonixin; Drug Labeling; Drug Residues; Female; Inflammation; Kidney; Lipopolysaccharides; Liver; Milk; Muscle, Skeletal; Sodium Chloride; Veterinary Drugs	2015
Distribution of Flunixin Residues in Muscles of Dairy Cattle Dosed with Lipopolysaccharide or Saline and Treated with Flunixin by Intravenous or Intramuscular Injection. Journal of agricultural and food chemistry, 2016, Dec-28, Volume: 64, Issue:51 Topics: Animals; Anti-Inflammatory Agents; Cattle; Cattle Diseases; Clonixin; Drug Residues; Inflammation; Injections, Intramuscular; Injections, Intravenous; Lipopolysaccharides; Muscle, Skeletal; Sodium Chloride; Veterinary Drugs	2016
In vivo characterization of inflammatory biomarkers in swine and the impact of flunixin meglumine administration. Veterinary immunology and immunopathology, 2012, Aug-15, Volume: 148, Issue:3-4 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigens, CD1; Biomarkers; Caspase 1; CD4 Antigens; Chemokine CCL2; Clonixin; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Inflammation; Lipopolysaccharides; Male; Real-Time Polymerase Chain Reaction; Serum Amyloid A Protein; Swine; Swine Diseases; Thromboxane B2	2012
Ethyl pyruvate diminishes the inflammatory response to lipopolysaccharide infusion in horses. Equine veterinary journal, 2013, Volume: 45, Issue:3 Topics: Actins; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Clonixin; Female; Gene Expression Regulation; Horse Diseases; Horses; Inflammation; Interleukin-6; Interleukin-8; Lipopolysaccharides; Male; Pyruvates; Tumor Necrosis Factor-alpha	2013
Evaluation of the ability of carprofen and flunixin meglumine to inhibit activation of nuclear factor kappa B. American journal of veterinary research, 2003, Volume: 64, Issue:2 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Cell Line; Clonixin; Cyclooxygenase Inhibitors; Enzyme Induction; Inflammation; Inhibitory Concentration 50; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phenylbutazone; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Sheep	2003
Flunixin inhibits prostaglandin E2 production in equine inflammation. Research in veterinary science, 1984, Volume: 37, Issue:3 Topics: Animals; Carrageenan; Clonixin; Depression, Chemical; Dinoprostone; Disease Models, Animal; Exudates and Transudates; Female; Horse Diseases; Horses; Inflammation; Male; Nicotinic Acids; Prostaglandins E; Proteins; Time Factors	1984
Non-steroidal anti-inflammatory agents in the horse. In practice, 1981, Volume: 3, Issue:5 Topics: Animals; Anti-Inflammatory Agents; Clonixin; Horse Diseases; Horses; Inflammation; Meclofenamic Acid; Naproxen; Phenylbutazone	1981
Determination of pharmacokinetics and pharmacodynamics of flunixin in calves by use of pharmacokinetic/pharmacodynamic modeling. American journal of veterinary research, 1995, Volume: 56, Issue:6 Topics: Acid Phosphatase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Clonixin; Cross-Over Studies; Cysteine Endopeptidases; Exudates and Transudates; Glucuronidase; Inflammation; L-Lactate Dehydrogenase; Lysosomes; Metabolic Clearance Rate; Metalloendopeptidases; Models, Biological; Serine Endopeptidases	1995
Comparative study of the action of flunixin meglumine and tolfenamic acid on prostaglandin E2 synthesis in bovine inflammatory exudate. Journal of veterinary pharmacology and therapeutics, 1994, Volume: 17, Issue:4 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cattle; Clonixin; Dinoprostone; Disease Models, Animal; Exudates and Transudates; Inflammation; Male; ortho-Aminobenzoates; Random Allocation	1994
Comparison of the anti-inflammatory actions of flunixin and ketoprofen in horses applying PK/PD modelling. Equine veterinary journal, 1995, Volume: 27, Issue:4 Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Clonixin; Cross-Over Studies; Dinoprostone; Exudates and Transudates; Glucuronidase; Half-Life; Horses; Inflammation; Ketoprofen; Leukotriene B4; Male; Models, Biological; Thromboxane B2	1995
Reversal by naloxone of the spinal antinociceptive actions of a systemically-administered NSAID. British journal of pharmacology, 1996, Volume: 118, Issue:4 Topics: Analgesics, Opioid; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Clonixin; Dose-Response Relationship, Drug; Electrophysiology; Excipients; Fentanyl; Inflammation; Male; Naloxone; Narcotic Antagonists; Rats; Rats, Wistar	1996
Preliminary pharmacokinetic and pharmacodynamic studies on flunixin meglumine in donkeys. Veterinary research communications, 1996, Volume: 20, Issue:5 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Clonixin; Dinoprostone; Equidae; Female; Inflammation; Metabolic Clearance Rate	1996
Measurement of cyclooxygenase inhibition in vivo: a study of two non-steroidal anti-inflammatory drugs in sheep. Inflammation, 1998, Volume: 22, Issue:4 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Clonixin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diffusion Chambers, Culture; Dinoprostone; Inflammation; Isoenzymes; Leukocyte Count; Leukotriene B4; Male; Phenylbutazone; Prostaglandin-Endoperoxide Synthases; Sheep; Skin Temperature; Thromboxane B2	1998
Pharmacokinetic studies of flunixin meglumine and phenylbutazone in plasma, exudate and transudate in sheep. Journal of veterinary pharmacology and therapeutics, 1998, Volume: 21, Issue:4 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Carrageenan; Clonixin; Cross-Over Studies; Exudates and Transudates; Half-Life; Inflammation; Injections, Intravenous; Male; Oxyphenbutazone; Phenylbutazone; Sheep	1998
Measurement of flunixin in equine inflammatory exudate and plasma by high performance liquid chromatography. Equine veterinary journal, 1987, Volume: 19, Issue:4 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Chromatography, High Pressure Liquid; Clonixin; Exudates and Transudates; Horse Diseases; Horses; Inflammation; Nicotinic Acids	1987
Effects of flunixin meglumine and dexamethasone on aqueous protein values after intraocular surgery in the dog. American journal of veterinary research, 1987, Volume: 48, Issue:3 Topics: Animals; Aqueous Humor; Clonixin; Dexamethasone; Dog Diseases; Dogs; Drug Therapy, Combination; Eye Proteins; Inflammation; Nicotinic Acids; Ophthalmologic Surgical Procedures; Postoperative Complications; Random Allocation	1987