clonidine has been researched along with Ventricular Fibrillation in 5 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
Ventricular Fibrillation: A potentially lethal cardiac arrhythmia that is characterized by uncoordinated extremely rapid firing of electrical impulses (400-600/min) in HEART VENTRICLES. Such asynchronous ventricular quivering or fibrillation prevents any effective cardiac output and results in unconsciousness (SYNCOPE). It is one of the major electrocardiographic patterns seen with CARDIAC ARREST.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The antiarrhythmic and antifibrillatory effects of the specific bradycardic agent alinidine were evaluated in a conscious canine model of myocardial infarction and sudden death, and by determination of ventricular fibrillation thresholds (VFT) in anesthetized dogs." | 7.67 | Alinidine reduces the incidence of ischemic ventricular fibrillation in a conscious canine model, a protective effect antagonized by overdrive atrial pacing. ( Chi, LG; Driscoll, EM; Frye, JW; Lucchesi, BR; Lynch, JJ; Uprichard, AC, 1989) |
| " ITC was delivered locally via catheter to the T2-T4 spinal segments and was dosed to reduce heart rate (HR) by >20% to 25%." | 5.33 | Intrathecal clonidine reduces the incidence of ischemia-provoked ventricular arrhythmias in a canine postinfarction heart failure model. ( Groh, WJ; Hildebrand, KR; Issa, ZF; Miller, JM; Rosenberger, J; Ujhelyi, MR; Zhou, X; Zipes, DP, 2005) |
| "The antiarrhythmic and antifibrillatory effects of the specific bradycardic agent alinidine were evaluated in a conscious canine model of myocardial infarction and sudden death, and by determination of ventricular fibrillation thresholds (VFT) in anesthetized dogs." | 3.67 | Alinidine reduces the incidence of ischemic ventricular fibrillation in a conscious canine model, a protective effect antagonized by overdrive atrial pacing. ( Chi, LG; Driscoll, EM; Frye, JW; Lucchesi, BR; Lynch, JJ; Uprichard, AC, 1989) |
| " ITC was delivered locally via catheter to the T2-T4 spinal segments and was dosed to reduce heart rate (HR) by >20% to 25%." | 1.33 | Intrathecal clonidine reduces the incidence of ischemia-provoked ventricular arrhythmias in a canine postinfarction heart failure model. ( Groh, WJ; Hildebrand, KR; Issa, ZF; Miller, JM; Rosenberger, J; Ujhelyi, MR; Zhou, X; Zipes, DP, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Issa, ZF | 1 |
| Ujhelyi, MR | 1 |
| Hildebrand, KR | 1 |
| Zhou, X | 1 |
| Rosenberger, J | 1 |
| Groh, WJ | 1 |
| Miller, JM | 1 |
| Zipes, DP | 1 |
| Rotenberg, FA | 1 |
| Verrier, RL | 2 |
| Lown, B | 1 |
| Sole, MJ | 1 |
| Uprichard, AC | 1 |
| Chi, LG | 1 |
| Lynch, JJ | 1 |
| Driscoll, EM | 1 |
| Frye, JW | 1 |
| Lucchesi, BR | 1 |
| Harron, DW | 1 |
| Brezina, M | 1 |
| Lillie, C | 1 |
| Kobinger, W | 1 |
5 other studies available for clonidine and Ventricular Fibrillation
| Article | Year |
|---|---|
Intrathecal clonidine reduces the incidence of ischemia-provoked ventricular arrhythmias in a canine postinfarction heart failure model.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Clonidine; Disease Models, Animal; Dogs; Electro | 2005 |
Effects of clonidine on vulnerability to fibrillation in the normal and ischemic canine ventricle.
Topics: Animals; Cisterna Magna; Clonidine; Coronary Disease; Coronary Vessels; Dogs; Electric Stimulation; | 1978 |
Alinidine reduces the incidence of ischemic ventricular fibrillation in a conscious canine model, a protective effect antagonized by overdrive atrial pacing.
Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Clonidine; Death, Sudden; D | 1989 |
Neurochemical approaches to the prevention of ventricular fibrillation.
Topics: Animals; Atropine; Brain Chemistry; Cardiac Glycosides; Clonidine; Disease Susceptibility; Dogs; Hum | 1986 |
Antifibrillatory properties of alinidine after coronary artery occlusion in rats.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiovascular Agents; Clonidine; Coronary Di | 1985 |