clonidine has been researched along with Ventricular Dysfunction, Left in 9 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
Ventricular Dysfunction, Left: A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We studied the effects of clonidine on cardiac sympathetic activity and left ventricular function in patients with congestive heart failure (CHF)." | 7.70 | Cardiac and systemic sympathetic activity in response to clonidine in human heart failure. ( Azevedo, ER; Newton, GE; Parker, JD, 1999) |
| " Clonidine is a potent sympatholytic drug with central neural effects." | 6.76 | The effects of clonidine on arterial baroreflex sensitivity and cardiopulmonary baroreflex control of sympathetic nerve activity in patients with left ventricular dysfunction. ( Iwasaka, T; Kawamura, A; Murakawa, K; Sugiura, T; Yokoe, H; Yoshida, S; Yuasa, F, 2011) |
| " ITC was delivered locally via catheter to the T2-T4 spinal segments and was dosed to reduce heart rate (HR) by >20% to 25%." | 5.33 | Intrathecal clonidine reduces the incidence of ischemia-provoked ventricular arrhythmias in a canine postinfarction heart failure model. ( Groh, WJ; Hildebrand, KR; Issa, ZF; Miller, JM; Rosenberger, J; Ujhelyi, MR; Zhou, X; Zipes, DP, 2005) |
| "We sought to assess the haemodynamic effects of clonidine on left ventricular (LV) pressure-volume relation in patients with diastolic heart dysfunction due to essential hypertension." | 5.09 | Acute effect of clonidine on left ventricular pressure-volume relation in hypertensive patients with diastolic heart dysfunction. ( Dernellis, J; Gavras, H; Gavras, I; Manolis, A; Stefanadis, C; Toutouzas, P; Tsiamis, E; Tsioufis, C, 2001) |
| "We studied the effects of clonidine on cardiac sympathetic activity and left ventricular function in patients with congestive heart failure (CHF)." | 3.70 | Cardiac and systemic sympathetic activity in response to clonidine in human heart failure. ( Azevedo, ER; Newton, GE; Parker, JD, 1999) |
| " Clonidine is a potent sympatholytic drug with central neural effects." | 2.76 | The effects of clonidine on arterial baroreflex sensitivity and cardiopulmonary baroreflex control of sympathetic nerve activity in patients with left ventricular dysfunction. ( Iwasaka, T; Kawamura, A; Murakawa, K; Sugiura, T; Yokoe, H; Yoshida, S; Yuasa, F, 2011) |
| "Treatment with clonidine markedly suppressed norepinephrine levels during exercise (matched peak exercise workload: control, 2137 +/- 187 versus clonidine, 1430 +/- 161 pg/mL), increased leg blood flow (control, 1." | 2.68 | Effect of sympathoinhibition on exercise performance in patients with heart failure. ( Chomsky, DB; Lang, CC; Rayos, GH; Wilson, JR; Wood, AJ, 1997) |
| " ITC was delivered locally via catheter to the T2-T4 spinal segments and was dosed to reduce heart rate (HR) by >20% to 25%." | 1.33 | Intrathecal clonidine reduces the incidence of ischemia-provoked ventricular arrhythmias in a canine postinfarction heart failure model. ( Groh, WJ; Hildebrand, KR; Issa, ZF; Miller, JM; Rosenberger, J; Ujhelyi, MR; Zhou, X; Zipes, DP, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 5 (55.56) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yuasa, F | 1 |
| Kawamura, A | 1 |
| Yokoe, H | 1 |
| Yoshida, S | 1 |
| Murakawa, K | 1 |
| Sugiura, T | 1 |
| Iwasaka, T | 1 |
| Eikelis, N | 1 |
| Schlaich, M | 1 |
| Aggarwal, A | 1 |
| Kaye, D | 1 |
| Esler, M | 1 |
| Detsky, ME | 1 |
| Azevedo, ER | 2 |
| Parker, JD | 2 |
| Tumak, VN | 1 |
| Dzizinskiĭ, AA | 1 |
| Issa, ZF | 1 |
| Ujhelyi, MR | 1 |
| Hildebrand, KR | 1 |
| Zhou, X | 1 |
| Rosenberger, J | 1 |
| Groh, WJ | 1 |
| Miller, JM | 1 |
| Zipes, DP | 1 |
| Lang, CC | 1 |
| Rayos, GH | 1 |
| Chomsky, DB | 1 |
| Wood, AJ | 1 |
| Wilson, JR | 1 |
| Newton, GE | 1 |
| Bîrsan, T | 1 |
| Kranz, A | 1 |
| Mares, P | 1 |
| Artemiou, O | 1 |
| Taghavi, S | 1 |
| Zuckermann, A | 1 |
| Klepetko, W | 1 |
| Stefanadis, C | 1 |
| Manolis, A | 1 |
| Dernellis, J | 1 |
| Tsioufis, C | 1 |
| Tsiamis, E | 1 |
| Gavras, I | 1 |
| Gavras, H | 1 |
| Toutouzas, P | 1 |
5 trials available for clonidine and Ventricular Dysfunction, Left
| Article | Year |
|---|---|
The effects of clonidine on arterial baroreflex sensitivity and cardiopulmonary baroreflex control of sympathetic nerve activity in patients with left ventricular dysfunction.
Topics: Adrenergic alpha-1 Receptor Agonists; Aged; Analysis of Variance; Arteries; Baroreflex; Blood Pressu | 2011 |
Interactions between leptin and the human sympathetic nervous system.
Topics: Adult; Aging; Antihypertensive Agents; Autonomic Nervous System Diseases; Clonidine; Epinephrine; Fe | 2003 |
[Clinical course of acute myocardial infarction and left ventricular function in long-term epidural analgesia].
Topics: Analgesia, Epidural; Analgesics; Analgesics, Opioid; Clonidine; Female; Humans; Injections, Intraven | 2004 |
Effect of sympathoinhibition on exercise performance in patients with heart failure.
Topics: Cardiomyopathy, Dilated; Chronic Disease; Clonidine; Coronary Disease; Exercise; Exercise Test; Hemo | 1997 |
Acute effect of clonidine on left ventricular pressure-volume relation in hypertensive patients with diastolic heart dysfunction.
Topics: Aged; Blood Pressure; Blood Volume; Clonidine; Diastole; Female; Humans; Hypertension; Male; Middle | 2001 |
4 other studies available for clonidine and Ventricular Dysfunction, Left
| Article | Year |
|---|---|
Left ventricular isovolumic relaxation is a predictor of left ventricular end-diastolic pressure.
Topics: Cardiac Catheterization; Clonidine; Diastole; Female; Heart Failure; Hemodynamics; Humans; Male; Mid | 2003 |
Intrathecal clonidine reduces the incidence of ischemia-provoked ventricular arrhythmias in a canine postinfarction heart failure model.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Clonidine; Disease Models, Animal; Dogs; Electro | 2005 |
Cardiac and systemic sympathetic activity in response to clonidine in human heart failure.
Topics: Adrenergic alpha-Agonists; Cardiomyopathy, Dilated; Clonidine; Coronary Circulation; Dose-Response R | 1999 |
Transient left ventricular failure following bilateral lung transplantation for pulmonary hypertension.
Topics: Adult; Alprostadil; Antihypertensive Agents; Cardiac Output, Low; Cardiotonic Agents; Catheterizatio | 1999 |