clonidine has been researched along with Urination Disorders in 4 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
Urination Disorders: Abnormalities in the process of URINE voiding, including bladder control, frequency of URINATION, as well as the volume and composition of URINE.
| Excerpt | Relevance | Reference |
|---|---|---|
| " However, the incidence of nocturnal enuresis, urgency attacks, and daytime incontinence were significantly reduced compared with baseline in the tizanidine group (P=." | 5.16 | Doxazosin versus tizanidine for treatment of dysfunctional voiding in children: a prospective randomized open-labeled trial. ( Dawaba, M; El-Assmy, MM; El-Hefnawy, AS; Hafez, AT; Helmy, T; Sarhan, O, 2012) |
| "This study evaluates the efficacy and side effects of a low dose of epidural morphine combined with clonidine for postoperative pain relief after lumbar disc surgery." | 2.70 | Epidural administration of low-dose morphine combined with clonidine for postoperative analgesia after lumbar disc surgery. ( Bonhomme, V; Brichant, JF; Dewandre, PY; Doll, A; Ghassempour, K; Hans, P, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| El-Hefnawy, AS | 1 |
| Helmy, T | 1 |
| El-Assmy, MM | 1 |
| Sarhan, O | 1 |
| Hafez, AT | 1 |
| Dawaba, M | 1 |
| Bonhomme, V | 1 |
| Doll, A | 1 |
| Dewandre, PY | 1 |
| Brichant, JF | 1 |
| Ghassempour, K | 1 |
| Hans, P | 1 |
| Gerstenbrand, F | 1 |
| Lorincz, A | 1 |
| Ludin, HP | 1 |
| Ringwald, E | 1 |
| Nordling, J | 1 |
| Meyhoff, HH | 1 |
| Christensen, NJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Prospective Triple-masked Randomized Controlled Trial Measuring Analgesia Duration of Dexamethasone, Buprenorphine, or Clonidine With Ropivacaine for Interscalene Nerve Block[NCT03117140] | Phase 4 | 160 participants (Actual) | Interventional | 2013-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Patients are assessed from needle removal to when they are no longer able to feel cold on the blocked extremity (NCT03117140)
Timeframe: Day one
| Intervention | minutes (Median) |
|---|---|
| Plain Ropivacaine | 6 |
| Ropivacaine + Buprenorphine | 3 |
| Ropivacaine + Clonidine | 6 |
| Ropivacaine + Dexamethasone | 4.5 |
Patients are called 1-3 days post-operatively to assess when the analgesia of their nerve block wore off (NCT03117140)
Timeframe: 1-3 days post-operative
| Intervention | minutes (Median) |
|---|---|
| Plain Ropivacaine | 911 |
| Ropivacaine + Buprenorphine | 1026.5 |
| Ropivacaine + Clonidine | 1181 |
| Ropivacaine + Dexamethasone | 982 |
Patients are called 1-3 days post-operatively to assess when motor component of their nerve block wore off (NCT03117140)
Timeframe: Day 1-3
| Intervention | minutes (Median) |
|---|---|
| Plain Ropivacaine | 1120 |
| Ropivacaine + Buprenorphine | 1198 |
| Ropivacaine + Clonidine | 1090 |
| Ropivacaine + Dexamethasone | 1143.5 |
Blood pressure changes in Second Stage Recovery Area for patients was looked at (NCT03117140)
Timeframe: Post-op Day 0 (baseline)
| Intervention | Participants (Count of Participants) |
|---|---|
| Plain Ropivacaine | 5 |
| Ropivacaine + Buprenorphine | 1 |
| Ropivacaine + Clonidine | 5 |
| Ropivacaine + Dexamethasone | 0 |
Patients are called 1-3 days post-operatively to assess if they had any side effects of the adjuvants such as nausea, vomiting or itching. There blood pressure is looked at pre-op and compared to post-op. Any prolonged PACU (Post Anesthesia Care Unit) stay for sedation is recorded. (NCT03117140)
Timeframe: 1-3 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Plain Ropivacaine | 1 |
| Ropivacaine + Buprenorphine | 2 |
| Ropivacaine + Clonidine | 2 |
| Ropivacaine + Dexamethasone | 0 |
Patients itching was assessed post-op in the PACU. (NCT03117140)
Timeframe: Post-op day 0 (baseline)
| Intervention | Participants (Count of Participants) |
|---|---|
| Plain Ropivacaine | 5 |
| Ropivacaine + Buprenorphine | 2 |
| Ropivacaine + Clonidine | 6 |
| Ropivacaine + Dexamethasone | 3 |
Patients are called 1-3 days post-operatively to assess if they had any side effects of the adjuvants such as nausea, vomiting or itching. There blood pressure is looked at pre-op and compared to post-op. Any prolonged PACU (Post Anesthesia Care Unit) stay for sedation is recorded. (NCT03117140)
Timeframe: 1-3 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Plain Ropivacaine | 4 |
| Ropivacaine + Buprenorphine | 9 |
| Ropivacaine + Clonidine | 2 |
| Ropivacaine + Dexamethasone | 3 |
PACU (Post-Anesthesia Care Unit) assessment of nausea (NCT03117140)
Timeframe: Post-op day 0 (Baseline)
| Intervention | Participants (Count of Participants) |
|---|---|
| Plain Ropivacaine | 4 |
| Ropivacaine + Buprenorphine | 9 |
| Ropivacaine + Clonidine | 2 |
| Ropivacaine + Dexamethasone | 9 |
Vomiting in PACU (Post-Anesthesia Care Unit) for patients was looked at (NCT03117140)
Timeframe: Post-op Day 0 (Baseline)
| Intervention | Participants (Count of Participants) |
|---|---|
| Plain Ropivacaine | 0 |
| Ropivacaine + Buprenorphine | 1 |
| Ropivacaine + Clonidine | 0 |
| Ropivacaine + Dexamethasone | 0 |
Blood pressure changes in PACU (Post-Anesthesia Care Unit) for patients was looked at (NCT03117140)
Timeframe: Post-op Day 0 (baseline)
| Intervention | Participants (Count of Participants) |
|---|---|
| Plain Ropivacaine | 8 |
| Ropivacaine + Buprenorphine | 3 |
| Ropivacaine + Clonidine | 7 |
| Ropivacaine + Dexamethasone | 2 |
Patients are called 1-3 days post-operatively to assess pain. Pain score is 0-10 scale with 0 is no pain and 10 is most severe pain. (NCT03117140)
Timeframe: Day 1-3
| Intervention | units on a scale (Median) |
|---|---|
| Plain Ropivacaine | 4 |
| Ropivacaine + Buprenorphine | 3 |
| Ropivacaine + Clonidine | 4 |
| Ropivacaine + Dexamethasone | 3 |
Patients are called 1-3 days post-operatively to assess if they had any side effects of the adjuvants such as nausea, vomiting or itching. There blood pressure is looked at pre-op and compared to post-op. Any prolonged PACU (Post Anesthesia Care Unit) stay for sedation is recorded. (NCT03117140)
Timeframe: 1-3 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Plain Ropivacaine | 0 |
| Ropivacaine + Buprenorphine | 3 |
| Ropivacaine + Clonidine | 2 |
| Ropivacaine + Dexamethasone | 1 |
Patients are called 1-3 days post-operatively to assess when the sensory component of their nerve block wore off (NCT03117140)
Timeframe: Day 1-3
| Intervention | minutes (Median) |
|---|---|
| Plain Ropivacaine | 923.5 |
| Ropivacaine + Buprenorphine | 982 |
| Ropivacaine + Clonidine | 940.5 |
| Ropivacaine + Dexamethasone | 1066 |
Surgical length was recorded (NCT03117140)
Timeframe: Post op Day 0 (Baseline)
| Intervention | minutes (Median) |
|---|---|
| Plain Ropivacaine | 68.5 |
| Ropivacaine + Buprenorphine | 65 |
| Ropivacaine + Clonidine | 73.5 |
| Ropivacaine + Dexamethasone | 71 |
Surgical position was recorded (NCT03117140)
Timeframe: Post-op Day 0 (Baseline)
| Intervention | Participants (Count of Participants) | ||
|---|---|---|---|
| Beach Chair | Lateral | Supine | |
| Plain Ropivacaine | 38 | 2 | 0 |
| Ropivacaine + Buprenorphine | 31 | 6 | 3 |
| Ropivacaine + Clonidine | 31 | 7 | 2 |
| Ropivacaine + Dexamethasone | 32 | 6 | 2 |
2 trials available for clonidine and Urination Disorders
| Article | Year |
|---|---|
Doxazosin versus tizanidine for treatment of dysfunctional voiding in children: a prospective randomized open-labeled trial.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Anorexia; Child; Chil | 2012 |
Epidural administration of low-dose morphine combined with clonidine for postoperative analgesia after lumbar disc surgery.
Topics: Adjuvants, Anesthesia; Adult; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics; Analge | 2002 |
2 other studies available for clonidine and Urination Disorders
| Article | Year |
|---|---|
[Long-term treatment with an imidazoline derivative (DS 103--282) (author's transl)].
Topics: Arm; Clonidine; Female; Humans; Leg; Male; Multiple Sclerosis; Muscle Spasticity; Paralysis; Urinati | 1979 |
Effects of clonidine (Catapresan) on urethral pressure.
Topics: Adult; Blood Pressure; Clonidine; Epinephrine; Female; Heart Rate; Humans; Male; Middle Aged; Norepi | 1979 |