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clonidine and Supranuclear Palsy, Progressive

clonidine has been researched along with Supranuclear Palsy, Progressive in 1 studies

Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.

Supranuclear Palsy, Progressive: A degenerative disease of the central nervous system characterized by balance difficulties; OCULAR MOTILITY DISORDERS (supranuclear ophthalmoplegia); DYSARTHRIA; swallowing difficulties; and axial DYSTONIA. Onset is usually in the fifth decade and disease progression occurs over several years. Pathologic findings include neurofibrillary degeneration and neuronal loss in the dorsal MESENCEPHALON; SUBTHALAMIC NUCLEUS; RED NUCLEUS; pallidum; dentate nucleus; and vestibular nuclei. (From Adams et al., Principles of Neurology, 6th ed, pp1076-7)

Research Excerpts

ExcerptRelevanceReference
"The clinical features of progressive supranuclear palsy (PSP) overlap with other parkinsonian syndromes, including multiple system atrophy (MSA)."2.69Physiological, pharmacological and neurohormonal assessment of autonomic function in progressive supranuclear palsy. ( Bleasdale-Barr, K; Chang, HS; Churchyard, A; Kimber, J; Lees, AJ; Mathias, CJ; Watson, L, 2000)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kimber, J1
Mathias, CJ1
Lees, AJ1
Bleasdale-Barr, K1
Chang, HS1
Churchyard, A1
Watson, L1

Trials

1 trial available for clonidine and Supranuclear Palsy, Progressive

ArticleYear
Physiological, pharmacological and neurohormonal assessment of autonomic function in progressive supranuclear palsy.
    Brain : a journal of neurology, 2000, Volume: 123 ( Pt 7)

    Topics: Adrenergic alpha-Agonists; Aged; Autonomic Nervous System; Blood Glucose; Blood Pressure; Cardiovasc

2000