clonidine has been researched along with Status Epilepticus in 3 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
Status Epilepticus: A prolonged seizure or seizures repeated frequently enough to prevent recovery between episodes occurring over a period of 20-30 minutes. The most common subtype is generalized tonic-clonic status epilepticus, a potentially fatal condition associated with neuronal injury and respiratory and metabolic dysfunction. Nonconvulsive forms include petit mal status and complex partial status, which may manifest as behavioral disturbances. Simple partial status epilepticus consists of persistent motor, sensory, or autonomic seizures that do not impair cognition (see also EPILEPSIA PARTIALIS CONTINUA). Subclinical status epilepticus generally refers to seizures occurring in an unresponsive or comatose individual in the absence of overt signs of seizure activity. (From N Engl J Med 1998 Apr 2;338(14):970-6; Neurologia 1997 Dec;12 Suppl 6:25-30)
| Excerpt | Relevance | Reference |
|---|---|---|
| " We suggest that modulation of sympathetic activity by atenolol provides a promising cardioprotective approach in status epilepticus." | 7.81 | Atenolol offers better protection than clonidine against cardiac injury in kainic acid-induced status epilepticus. ( Harrison, JC; Kerr, DS; Read, MI; Sammut, IA, 2015) |
| "Clonidine treatment attenuated seizure activity, increased the latency to onset of seizure behaviour and reduced seizure-induced changes in heart rate, QTc interval, and T wave amplitude." | 5.40 | Cardiac electrographic and morphological changes following status epilepticus: effect of clonidine. ( Andreianova, AA; Goulton, CS; Harrison, JC; Kerr, DS; Read, MI; Sammut, IA, 2014) |
| " We suggest that modulation of sympathetic activity by atenolol provides a promising cardioprotective approach in status epilepticus." | 3.81 | Atenolol offers better protection than clonidine against cardiac injury in kainic acid-induced status epilepticus. ( Harrison, JC; Kerr, DS; Read, MI; Sammut, IA, 2015) |
| "Clonidine treatment attenuated seizure activity, increased the latency to onset of seizure behaviour and reduced seizure-induced changes in heart rate, QTc interval, and T wave amplitude." | 1.40 | Cardiac electrographic and morphological changes following status epilepticus: effect of clonidine. ( Andreianova, AA; Goulton, CS; Harrison, JC; Kerr, DS; Read, MI; Sammut, IA, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Read, MI | 2 |
| Andreianova, AA | 1 |
| Harrison, JC | 2 |
| Goulton, CS | 1 |
| Sammut, IA | 2 |
| Kerr, DS | 2 |
| Feron, FJ | 1 |
| Hendriksen, JG | 1 |
| Nicolai, J | 1 |
| Vles, JS | 1 |
3 other studies available for clonidine and Status Epilepticus
| Article | Year |
|---|---|
Cardiac electrographic and morphological changes following status epilepticus: effect of clonidine.
Topics: Animals; Clonidine; Double-Blind Method; Electrocardiography; Heart; Male; Myocardial Infarction; My | 2014 |
Atenolol offers better protection than clonidine against cardiac injury in kainic acid-induced status epilepticus.
Topics: Animals; Atenolol; Behavior, Animal; Cardiotonic Agents; Clonidine; Electrocardiography; Electroence | 2015 |
New-onset seizures: a possible association with clonidine?
Topics: Adrenergic alpha-Agonists; Anticonvulsants; Attention Deficit Disorder with Hyperactivity; Cerebral | 2008 |