Page last updated: 2024-10-25

clonidine and Sinusitis

clonidine has been researched along with Sinusitis in 6 studies

Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.

Sinusitis: Inflammation of the NASAL MUCOSA in one or more of the PARANASAL SINUSES.

Research Excerpts

ExcerptRelevanceReference
"Twenty-six patients undergoing ESS for chronic sinusitis and polyp removal were enrolled and randomly assigned to receive either oral clonidine or melatonin as preoperative premedication."5.19Improved quality of surgical field during endoscopic sinus surgery after clonidine premedication--a pilot study. ( Burduk, PK; Cywinski, JB; Kazmierczak, W; Kusza, K; Wawrzyniak, K, 2014)
"A group of 44 patients undergoing FESS for chronic sinusitis and polyp removal were enrolled and randomly assigned to receive either oral clonidine or midazolam as preoperative premedication."5.17Premedication with clonidine before TIVA optimizes surgical field visualization and shortens duration of endoscopic sinus surgery - results of a clinical trial. ( Burduk, PK; Cywinski, JB; Kazmierczak, W; Kusza, K; Wawrzyniak, K, 2013)
"The technique of controlled hypotonia was developed for adequate management of anesthesia in endonasal microsurgical interventions on the paranasal sinuses in patients with chronic rhinosinusitis."1.31[The use of controlled hypotonia in endonasal microsurgical interventions on the paranasal sinuses in patients with chronic rhinosinusitis]. ( Iurchenko, LV; Zakharov, GP, 2000)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's5 (83.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Escamilla, Y2
Cardesín, A2
Samara, L1
López, S1
Izquierdo, A1
Fradera, M1
Vives, R1
Bernal-Sprekelsen, M2
Pontes, C2
Wawrzyniak, K2
Kusza, K2
Cywinski, JB2
Burduk, PK2
Kazmierczak, W2
Rosell, R1
Marco, J1
Escobar, MJ1
Mohseni, M1
Ebneshahidi, A1
Zakharov, GP1
Iurchenko, LV1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparative Study of Influence of Surgical Pleth Index Guided Total Intravenous Anaesthesia (TIVA) or Volatile Anaesthesia Using Sevoflurane or Desflurane on the Intraoperative Blood Loss During Functional Endoscopic Sinus Surgery[NCT03417180]120 participants (Anticipated)Interventional2018-09-01Recruiting
Comparative Study of Influence of Total Intravenous Anaesthesia (TIVA) and Volatile Anaesthesia Using Sevoflurane or Desflurane on the Intraoperative Blood Loss During Functional Endoscopic Sinus Surgery[NCT03417206]120 participants (Anticipated)Interventional2021-09-01Not yet recruiting
Comparative Study of Influence of Different Techniques of Remifentanil Titration During Functional Endoscopic Sinus Surgery Under Total Intravenous Anaesthesia (TIVA)[NCT03389763]105 participants (Actual)Interventional2016-06-01Completed
Effect of Pre-operative Oral Steroids on Blood Loss in Endoscopic Sinus Surgery for Chronic Rhinosinusitis Without Polyps[NCT05095961]Phase 2/Phase 30 participants (Actual)Interventional2023-03-31Withdrawn (stopped due to Technical difficulties encountered with recording intraoperative blood loss; unable to proceed with study.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

4 trials available for clonidine and Sinusitis

ArticleYear
Randomized clinical trial to compare the efficacy to improve the quality of surgical field of hypotensive anesthesia with clonidine or dexmedetomidine during functional endoscopic sinus surgery.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2019, Volume: 276, Issue:11

    Topics: Adrenergic alpha-2 Receptor Agonists; Anesthesia; Blood Loss, Surgical; Chronic Disease; Clonidine;

2019
Premedication with clonidine before TIVA optimizes surgical field visualization and shortens duration of endoscopic sinus surgery - results of a clinical trial.
    Rhinology, 2013, Volume: 51, Issue:3

    Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Aged; Blood Loss, Surgical; Chronic Disease; Clonidine;

2013
Improved quality of surgical field during endoscopic sinus surgery after clonidine premedication--a pilot study.
    International forum of allergy & rhinology, 2014, Volume: 4, Issue:7

    Topics: Adult; Arterial Pressure; Chronic Disease; Clonidine; Endoscopy; Female; Heart Rate; Hemodynamics; H

2014
The effect of oral clonidine premedication on blood loss and the quality of the surgical field during endoscopic sinus surgery: a placebo-controlled clinical trial.
    Journal of anesthesia, 2011, Volume: 25, Issue:4

    Topics: Adult; Anesthesia; Blood Loss, Surgical; Clonidine; Endoscopy; Female; Humans; Male; Placebos; Preme

2011

Other Studies

2 other studies available for clonidine and Sinusitis

ArticleYear
Hypotensive anaesthesia and bleeding during endoscopic sinus surgery: an observational study.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2014, Volume: 271, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Analgesics, Opioid; Anesthesia, General; Blo

2014
Hypotensive anaesthesia and bleeding during endoscopic sinus surgery: an observational study.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2014, Volume: 271, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Analgesics, Opioid; Anesthesia, General; Blo

2014
Hypotensive anaesthesia and bleeding during endoscopic sinus surgery: an observational study.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2014, Volume: 271, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Analgesics, Opioid; Anesthesia, General; Blo

2014
Hypotensive anaesthesia and bleeding during endoscopic sinus surgery: an observational study.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2014, Volume: 271, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Analgesics, Opioid; Anesthesia, General; Blo

2014
Hypotensive anaesthesia and bleeding during endoscopic sinus surgery: an observational study.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2014, Volume: 271, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Analgesics, Opioid; Anesthesia, General; Blo

2014
Hypotensive anaesthesia and bleeding during endoscopic sinus surgery: an observational study.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2014, Volume: 271, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Analgesics, Opioid; Anesthesia, General; Blo

2014
Hypotensive anaesthesia and bleeding during endoscopic sinus surgery: an observational study.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2014, Volume: 271, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Analgesics, Opioid; Anesthesia, General; Blo

2014
Hypotensive anaesthesia and bleeding during endoscopic sinus surgery: an observational study.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2014, Volume: 271, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Analgesics, Opioid; Anesthesia, General; Blo

2014
Hypotensive anaesthesia and bleeding during endoscopic sinus surgery: an observational study.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2014, Volume: 271, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Analgesics, Opioid; Anesthesia, General; Blo

2014
[The use of controlled hypotonia in endonasal microsurgical interventions on the paranasal sinuses in patients with chronic rhinosinusitis].
    Vestnik otorinolaringologii, 2000, Issue:4

    Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Aged; Chronic Disease; Clonidine; Humans; Microsurgery

2000