Page last updated: 2024-10-25

clonidine and Restless Legs Syndrome

clonidine has been researched along with Restless Legs Syndrome in 10 studies

Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.

Restless Legs Syndrome: A disorder characterized by aching or burning sensations in the lower and rarely the upper extremities that occur prior to sleep or may awaken the patient from sleep.

Research Excerpts

ExcerptRelevanceReference
"Ten patients with idiopathic restless leg syndrome (RLS) were asked to rate their symptoms at baseline during 2 weeks of placebo and 2 weeks of clonidine treatment by using a four-point scale."9.08Randomized, Double-Blind, Placebo-Controlled Study of Clonidine in Restless Legs Syndrome. ( Chokroverty, S; Coleman, RG; Grasing, K; Hening, WA; Wagner, ML; Walters, AS, 1996)
"Restless legs syndrome is a common and sometimes incapacitating disorder in chronic uraemic patients."6.66[Successful clonidine treatment of restless leg syndrome in chronic kidney insufficiency]. ( Ausserwinkler, M; Schmidt, P, 1989)
"Ten patients with idiopathic restless leg syndrome (RLS) were asked to rate their symptoms at baseline during 2 weeks of placebo and 2 weeks of clonidine treatment by using a four-point scale."5.08Randomized, Double-Blind, Placebo-Controlled Study of Clonidine in Restless Legs Syndrome. ( Chokroverty, S; Coleman, RG; Grasing, K; Hening, WA; Wagner, ML; Walters, AS, 1996)
"Restless legs syndrome is a common and sometimes incapacitating disorder in chronic uraemic patients."2.66[Successful clonidine treatment of restless leg syndrome in chronic kidney insufficiency]. ( Ausserwinkler, M; Schmidt, P, 1989)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19905 (50.00)18.7374
1990's2 (20.00)18.2507
2000's2 (20.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Amos, LB1
Grekowicz, ML1
Kuhn, EM1
Olstad, JD1
Collins, MM1
Norins, NA1
D'Andrea, LA1
Schapira, AH1
Cortese, S1
Lecendreux, M1
Mouren, MC1
Konofal, E1
Wagner, ML1
Walters, AS2
Coleman, RG1
Hening, WA2
Grasing, K1
Chokroverty, S2
Sandyk, R2
Ausserwinkler, M1
Schmidt, P1
Bamford, CR1
Bastani, B1
Westervelt, FB1
Handwerker, JV1
Palmer, RF1

Reviews

3 reviews available for clonidine and Restless Legs Syndrome

ArticleYear
Restless legs syndrome: an update on treatment options.
    Drugs, 2004, Volume: 64, Issue:2

    Topics: Analgesics, Opioid; Anticonvulsants; Benzodiazepines; Clinical Trials as Topic; Clonidine; Diagnosis

2004
Review and videotape recognition of idiopathic restless legs syndrome.
    Movement disorders : official journal of the Movement Disorder Society, 1991, Volume: 6, Issue:2

    Topics: Anti-Anxiety Agents; Arousal; Baclofen; Benzodiazepines; Bromocriptine; Carbamazepine; Clonidine; Hu

1991
The endogenous opioid system in neurological disorders of the basal ganglia.
    Life sciences, 1985, Nov-04, Volume: 37, Issue:18

    Topics: Animals; Antipsychotic Agents; Basal Ganglia Diseases; Clonidine; Endorphins; gamma-Aminobutyric Aci

1985

Trials

2 trials available for clonidine and Restless Legs Syndrome

ArticleYear
Randomized, Double-Blind, Placebo-Controlled Study of Clonidine in Restless Legs Syndrome.
    Sleep, 1996, Volume: 19, Issue:1

    Topics: Adrenergic Agonists; Adult; Age of Onset; Clonidine; Double-Blind Method; Electroencephalography; Fe

1996
[Successful clonidine treatment of restless leg syndrome in chronic kidney insufficiency].
    Schweizerische medizinische Wochenschrift, 1989, Feb-11, Volume: 119, Issue:6

    Topics: Adult; Aged; Clonidine; Double-Blind Method; Drug Evaluation; Female; Humans; Kidney Failure, Chroni

1989

Other Studies

5 other studies available for clonidine and Restless Legs Syndrome

ArticleYear
Treatment of pediatric restless legs syndrome.
    Clinical pediatrics, 2014, Volume: 53, Issue:4

    Topics: Adolescent; Amines; Analgesics; Anticonvulsants; Antioxidants; Benzothiazoles; Child; Child, Prescho

2014
ADHD and insomnia.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2006, Volume: 45, Issue:4

    Topics: Antidepressive Agents; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimula

2006
Failure of clonidine to ameliorate the symptoms of restless legs syndrome.
    Sleep, 1987, Volume: 10, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Clonidine; Drug Evaluation; Female; Humans; Male; Middle Aged; Restl

1987
Effectiveness of clonidine in alleviating the symptoms of "restless legs".
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1987, Volume: 10, Issue:4

    Topics: Clonidine; Dialysis; Female; Humans; Male; Middle Aged; Restless Legs Syndrome

1987
Clonidine in the treatment of "restless leg" syndrome.
    The New England journal of medicine, 1985, Nov-07, Volume: 313, Issue:19

    Topics: Adult; Aged; Clonidine; Female; Humans; Male; Middle Aged; Restless Legs Syndrome

1985