clonidine has been researched along with Respiratory Insufficiency in 17 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
Respiratory Insufficiency: Failure to adequately provide oxygen to cells of the body and to remove excess carbon dioxide from them. (Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In the newborn rat, morphine causes profound respiratory depression and hypothermia while clonidine causes minimal respiratory depression and stabilizes CBT." | 3.80 | Breathing and temperature control disrupted by morphine and stabilized by clonidine in neonatal rats. ( Bierman, A; Ezell, T; Gauda, EB; Kesavan, K; Northington, FJ; Nunes, AR; Tankersley, CG, 2014) |
| "Clonidine is a sedative-sparing agent and this can help reduce complications associated with prolonged use of opioids and benzodiazepines." | 1.72 | Use of continuous infusion of clonidine for sedation in critically ill infants and children. ( Bourdon, O; Dauger, S; Deho, A; Prot-Labarthe, S; Sadozai, L, 2022) |
| "Because of acute renal failure resulting from rhabdomyolysis hemodialysis was necessary three times." | 1.35 | ["Liquid ecstasy": gamma-butyrolactone withdrawal delirium with rhabdomyolysis and dialysis dependent renal failure]. ( Busch, HJ; Schwab, T; Supady, A, 2009) |
| "Assessment of respiratory depression caused by long-term sedation with sufentanil, midazolam and clonidine." | 1.31 | Respiratory depression under long-term sedation with sufentanil, midazolam and clonidine has no clinical significance. ( Bause, H; Prause, A; Scholz, J; Schulte am Esch, J; Wappler, F, 2000) |
| "To analyze the trends, demographics, and toxic effects associated with pediatric clonidine hydrochloride exposures reported to poison centers." | 1.31 | Trends and toxic effects from pediatric clonidine exposures. ( Klein-Schwartz, W, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (17.65) | 18.7374 |
| 1990's | 2 (11.76) | 18.2507 |
| 2000's | 9 (52.94) | 29.6817 |
| 2010's | 2 (11.76) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Sadozai, L | 1 |
| Prot-Labarthe, S | 1 |
| Bourdon, O | 1 |
| Dauger, S | 1 |
| Deho, A | 1 |
| Kesavan, K | 1 |
| Ezell, T | 1 |
| Bierman, A | 1 |
| Nunes, AR | 1 |
| Northington, FJ | 1 |
| Tankersley, CG | 1 |
| Gauda, EB | 1 |
| Liatsi, D | 1 |
| Tsapas, B | 1 |
| Pampori, S | 1 |
| Tsagourias, M | 1 |
| Pneumatikos, I | 1 |
| Matamis, D | 1 |
| Aouad, MT | 1 |
| Moukaddem, FH | 1 |
| Akel, SR | 1 |
| Kanazi, GE | 1 |
| Garg, R | 1 |
| Supady, A | 1 |
| Schwab, T | 1 |
| Busch, HJ | 1 |
| Rakesh, SV | 1 |
| Rajeev, S | 1 |
| Batra, YK | 1 |
| Rao, KL | 1 |
| da Silva, PS | 1 |
| Passos, RM | 1 |
| Waisberg, DR | 1 |
| Huitink, J | 1 |
| Buitelaar, D | 1 |
| Hansen, TG | 1 |
| Henneberg, SW | 1 |
| Metz, G | 1 |
| Nebel, B | 1 |
| Luebbe, N | 1 |
| Walz, R | 1 |
| Walz, K | 1 |
| Kiesel, C | 1 |
| Bornscheuer, A | 1 |
| Bîrsan, T | 1 |
| Kranz, A | 1 |
| Mares, P | 1 |
| Artemiou, O | 1 |
| Taghavi, S | 1 |
| Zuckermann, A | 1 |
| Klepetko, W | 1 |
| Prause, A | 1 |
| Wappler, F | 1 |
| Scholz, J | 1 |
| Bause, H | 1 |
| Schulte am Esch, J | 1 |
| Klein-Schwartz, W | 1 |
| Conner, CS | 1 |
| Watanabe, AS | 1 |
| Persico, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Clonidine vs. Dexmedetomidine in Addition to Standard Treatment in Agitated Delirium in Intensive Care Patients: Pilot Study.[NCT04758936] | Phase 4 | 50 participants (Anticipated) | Interventional | 2021-02-01 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for clonidine and Respiratory Insufficiency
| Article | Year |
|---|---|
Clonidine overdose: a review.
Topics: Adolescent; Adult; Cardiovascular Diseases; Child, Preschool; Clonidine; Coma; Female; Humans; Hypot | 1979 |
1 trial available for clonidine and Respiratory Insufficiency
| Article | Year |
|---|---|
Clonidine prolongs fentanyl-induced ventilatory depression.
Topics: Adrenergic alpha-Agonists; Adult; Analysis of Variance; Anesthesia, Closed-Circuit; Anesthetics, Int | 1998 |
15 other studies available for clonidine and Respiratory Insufficiency
| Article | Year |
|---|---|
Use of continuous infusion of clonidine for sedation in critically ill infants and children.
Topics: Bradycardia; Child, Preschool; Clonidine; Critical Care; Critical Illness; Female; Humans; Hypnotics | 2022 |
Breathing and temperature control disrupted by morphine and stabilized by clonidine in neonatal rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Animals, Newborn; Body Temperature; Carbon Dioxide; C | 2014 |
Respiratory, metabolic and hemodynamic effects of clonidine in ventilated patients presenting with withdrawal syndrome.
Topics: Adrenergic alpha-Agonists; Adult; Calorimetry, Indirect; Carbon Dioxide; Clonidine; Electrocardiogra | 2009 |
Respiratory failure in a former preterm infant following high spinal anesthesia with bupivacaine and clonidine.
Topics: Adrenergic alpha-Agonists; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Clonidine; Humans; I | 2008 |
Be vigilant during use of intrathecal clonidine in former preterm infants.
Topics: Analgesics; Anesthesia, Spinal; Clonidine; Humans; Infant; Infant, Newborn; Infant, Premature; Injec | 2009 |
["Liquid ecstasy": gamma-butyrolactone withdrawal delirium with rhabdomyolysis and dialysis dependent renal failure].
Topics: 4-Butyrolactone; Acute Kidney Injury; Adrenergic alpha-Agonists; Benzodiazepines; Clonidine; GABA Mo | 2009 |
Cephalad migration of intrathecal clonidine in an infant undergoing bilateral herniorrhaphy.
Topics: Adrenergic alpha-Agonists; Clonidine; Hernia, Inguinal; Humans; Infant; Injections, Spinal; Intraope | 2009 |
Withdrawal treatment with clonidine after prolonged use of chloral hydrate in a pediatric intensive care patient.
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Chloral Hydrate; Clonidine; Fentanyl; Humans; Hypnoti | 2011 |
Management of drug and alcohol withdrawal.
Topics: Alcoholism; Benzodiazepines; Clonidine; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; | 2003 |
Caudal clonidine in neonates and small infants and respiratory depression.
Topics: Analgesics; Anesthesia, Caudal; Anesthetics, Local; Clonidine; Humans; Infant; Infant, Newborn; Resp | 2004 |
[Clonidine in severe alcohol withdrawal delirium].
Topics: Alcohol Withdrawal Delirium; Chlormethiazole; Clonidine; Diazepam; Haloperidol; Humans; Monitoring, | 1983 |
Transient left ventricular failure following bilateral lung transplantation for pulmonary hypertension.
Topics: Adult; Alprostadil; Antihypertensive Agents; Cardiac Output, Low; Cardiotonic Agents; Catheterizatio | 1999 |
Respiratory depression under long-term sedation with sufentanil, midazolam and clonidine has no clinical significance.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Anesthetics, Intravenous; Carbon Dioxide; Ch | 2000 |
Trends and toxic effects from pediatric clonidine exposures.
Topics: Adolescent; Adrenergic alpha-Agonists; Age Distribution; Attention Deficit Disorder with Hyperactivi | 2002 |
[Pathogenesis and therapy of acute pulmonary edema].
Topics: Acute Disease; Brain Diseases; Cardiac Glycosides; Clonidine; Diuretics; Gas Poisoning; Heart Defect | 1972 |