Page last updated: 2024-10-25

clonidine and Renal Insufficiency, Chronic

clonidine has been researched along with Renal Insufficiency, Chronic in 1 studies

Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.

Renal Insufficiency, Chronic: Conditions in which the KIDNEYS perform below the normal level for more than three months. Chronic kidney insufficiency is classified by five stages according to the decline in GLOMERULAR FILTRATION RATE and the degree of kidney damage (as measured by the level of PROTEINURIA). The most severe form is the end-stage renal disease (CHRONIC KIDNEY FAILURE). (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Garg, AX1
Kurz, A1
Sessler, DI1
Cuerden, M1
Robinson, A1
Mrkobrada, M1
Parikh, C1
Mizera, R1
Jones, PM1
Tiboni, M1
Rodriguez, RG1
Popova, E1
Rojas Gomez, MF1
Meyhoff, CS1
Vanhelder, T1
Chan, MT1
Torres, D1
Parlow, J1
de Nadal Clanchet, M1
Amir, M1
Bidgoli, SJ1
Pasin, L1
Martinsen, K1
Malaga, G1
Myles, P1
Acedillo, R1
Roshanov, P1
Walsh, M1
Dresser, G1
Kumar, P1
Fleischmann, E1
Villar, JC1
Painter, T1
Biccard, B1
Bergese, S1
Srinathan, S1
Cata, JP1
Chan, V1
Mehra, B1
Leslie, K1
Whitlock, R1
Devereaux, PJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Large, International, Placebo-controlled, Factorial Trial to Assess the Impact of Clonidine and Acetyl-salicylic Acid (ASA) in Patients Undergoing Noncardiac Surgery Who Are at Risk of a Perioperative Cardiovascular Event[NCT01082874]Phase 310,010 participants (Actual)Interventional2010-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Composite of All-cause Mortality and Nonfatal MI

(NCT01082874)
Timeframe: 30 days

Interventionparticipants (Number)
Active Clonidine and Active ASA173
Active Clonidine and Placebo ASA194
Placebo Clonidine and Active ASA178
Placebo Clonidine and Placebo ASA161

Trials

1 trial available for clonidine and Renal Insufficiency, Chronic

ArticleYear
Aspirin and clonidine in non-cardiac surgery: acute kidney injury substudy protocol of the Perioperative Ischaemic Evaluation (POISE) 2 randomised controlled trial.
    BMJ open, 2014, Feb-25, Volume: 4, Issue:2

    Topics: Acute Kidney Injury; Adrenergic alpha-2 Receptor Agonists; Anti-Inflammatory Agents, Non-Steroidal;

2014