clonidine has been researched along with Psychotic Disorders in 16 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
Psychotic Disorders: Disorders in which there is a loss of ego boundaries or a gross impairment in reality testing with delusions or prominent hallucinations. (From DSM-IV, 1994)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Clonidine was selected because it blocks noradrenergic but not dopaminergic neurotransmission." | 6.65 | Clonidine treatment of schizophrenia. Double-blind comparison to placebo and neuroleptic drugs. ( Adler, LE; Bell, J; Denver, P; Freedman, R; Kirch, D; Pachtman, E; Pecevich, M, 1982) |
| "Clonidine is a centrally acting antihypertensive and has been prescribed widely for more than 20 years." | 2.69 | Clonidine does not potentiate the antipsychotic effects of neuroleptics in chronically ill patients. ( Bigelow, LB; El-Mallakh, RS; Elkashef, A; Hedges, S; Issa, F; Wyatt, RJ, 1998) |
| "Clonidine was selected because it blocks noradrenergic but not dopaminergic neurotransmission." | 2.65 | Clonidine treatment of schizophrenia. Double-blind comparison to placebo and neuroleptic drugs. ( Adler, LE; Bell, J; Denver, P; Freedman, R; Kirch, D; Pachtman, E; Pecevich, M, 1982) |
| "Our findings suggest that patients with endogenous depression are characterized by a subsensitivity of postsynaptic alpha-receptors or of structures related to them." | 1.26 | Effect of clonidine on growth hormone release in psychiatric patients and controls. ( Ackenheil, M; Hippius, H; Matussek, N; Müller, F; Schröder, HT; Schultes, H; Wasilewski, B, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (75.00) | 18.7374 |
| 1990's | 2 (12.50) | 18.2507 |
| 2000's | 2 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sahoo, M | 1 |
| Subho, C | 1 |
| Garver, DL | 1 |
| Adler, LE | 2 |
| Bell, J | 2 |
| Kirch, D | 2 |
| Friedrich, E | 1 |
| Freedman, R | 2 |
| Pecevich, M | 1 |
| Pachtman, E | 1 |
| Denver, P | 1 |
| Matussek, N | 2 |
| Ackenheil, M | 1 |
| Hippius, H | 1 |
| Müller, F | 1 |
| Schröder, HT | 1 |
| Schultes, H | 1 |
| Wasilewski, B | 1 |
| Judd, LL | 1 |
| Parker, DC | 1 |
| Janowsky, DS | 1 |
| Segal, DS | 1 |
| Risch, SC | 1 |
| Huey, LY | 1 |
| Lechin, F | 1 |
| van der Dijs, B | 1 |
| Wilens, TE | 1 |
| Spencer, T | 1 |
| Biederman, J | 1 |
| Wozniak, J | 1 |
| Connor, D | 1 |
| Hedges, S | 1 |
| El-Mallakh, RS | 1 |
| Issa, F | 1 |
| Elkashef, A | 1 |
| Bigelow, LB | 1 |
| Wyatt, RJ | 1 |
| Mokrani, M | 1 |
| Duval, F | 1 |
| Diep, TS | 1 |
| Bailey, PE | 1 |
| Macher, JP | 1 |
| Allen, RM | 1 |
| Flemenbaum, A | 1 |
| Singh, S | 1 |
| Subramaniam, M | 1 |
| Sato, T | 1 |
| Igarashi, N | 1 |
| Minami, S | 1 |
| Okabe, T | 1 |
| Hashimoto, H | 1 |
| Hasui, M | 1 |
| Kato, E | 1 |
| Bondy, B | 1 |
| Angrist, B | 1 |
| Smith, M | 1 |
| Adler, L | 1 |
| Peselow, E | 1 |
| Reitano, J | 1 |
| Rotrosen, J | 1 |
| Wålinder, J | 1 |
1 review available for clonidine and Psychotic Disorders
| Article | Year |
|---|---|
Ethnic differences in reactions to drugs and xenobiotics. Receptor and binding proteins in endogenous psychoses.
Topics: Antipsychotic Agents; Clonidine; Depressive Disorder; Dopamine; Female; Growth Hormone; Humans; Lith | 1986 |
3 trials available for clonidine and Psychotic Disorders
| Article | Year |
|---|---|
Clonidine treatment of schizophrenia. Double-blind comparison to placebo and neuroleptic drugs.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Blood Pressure; Clinical Trials as Topic; Clonidine; | 1982 |
The effect of methadone on the behavioral and neuroendocrine responses of manic patients.
Topics: Adult; Affective Disorders, Psychotic; Bipolar Disorder; Clonidine; Growth Hormone; Humans; Hydrocor | 1982 |
Clonidine does not potentiate the antipsychotic effects of neuroleptics in chronically ill patients.
Topics: Adjuvants, Pharmaceutic; Adrenergic alpha-Agonists; Adult; Antipsychotic Agents; Chronic Disease; Cl | 1998 |
12 other studies available for clonidine and Psychotic Disorders
| Article | Year |
|---|---|
Cortisol hypersecretion in unipolar major depression with melancholic and psychotic features: dopaminergic, noradrenergic and thyroid correlates.
Topics: Clonidine; Depressive Disorder; Depressive Disorder, Major; Dopamine; Growth Hormone; Humans; Hydroc | 2007 |
A psychobiologic perspective in treating psychiatric disorders.
Topics: Anxiety Disorders; Clonidine; Humans; Lithium; Mental Disorders; Mood Disorders; Psychotic Disorders | 1984 |
Psychosis associated with clonidine withdrawal.
Topics: Adult; Antipsychotic Agents; Bipolar Disorder; Clonidine; Female; Humans; Hypertension, Malignant; M | 1982 |
Effect of clonidine on growth hormone release in psychiatric patients and controls.
Topics: Adult; Alcohol Drinking; Bipolar Disorder; Clonidine; Depressive Disorder; Female; Growth Hormone; H | 1980 |
Clonidine therapy for psychosis and tardive dyskinesia.
Topics: Clonidine; Dyskinesia, Drug-Induced; Humans; Psychotic Disorders | 1981 |
Combined pharmacotherapy: an emerging trend in pediatric psychopharmacology.
Topics: Anxiety Disorders; Attention Deficit Disorder with Hyperactivity; Benzodiazepines; Child Psychiatry; | 1995 |
Multihormonal responses to clonidine in patients with affective and psychotic symptoms.
Topics: Adrenocorticotropic Hormone; Adult; Clonidine; Depressive Disorder, Major; Female; Hormones; Human G | 2000 |
Delirium associated with combined fluphenazine-clonidine therapy.
Topics: Adult; Clonidine; Delirium; Drug Therapy, Combination; Fluphenazine; Humans; Hypertension; Male; Psy | 1979 |
Failure of clonidine in tardive dystonia: implications for nosology.
Topics: Adult; Antipsychotic Agents; Clonidine; Dose-Response Relationship, Drug; Drug Therapy, Combination; | 1989 |
Recurrent attacks of vomiting, hypertension and psychotic depression: a syndrome of periodic catecholamine and prostaglandin discharge.
Topics: Adolescent; Adrenocorticotropic Hormone; Arginine Vasopressin; Child, Preschool; Clonidine; Dinopros | 1988 |
Preliminary studies of clonidine in psychotic patients.
Topics: Adult; Anxiety; Clonidine; Female; Humans; Male; Middle Aged; Psychotic Disorders | 1988 |
The use of clonidine in psychiatric disorders. Preliminary clinical observations.
Topics: Anxiety Disorders; Bipolar Disorder; Clonidine; Humans; Mental Disorders; Panic; Psychophysiologic D | 1986 |