clonidine has been researched along with Prostatic Hyperplasia in 6 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
Prostatic Hyperplasia: Increase in constituent cells in the PROSTATE, leading to enlargement of the organ (hypertrophy) and adverse impact on the lower urinary tract function. This can be caused by increased rate of cell proliferation, reduced rate of cell death, or both.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Dose-response curves were generated for para-aminoclonidine in the presence of vehicle alone, yohimbine (alpha-2 antagonist), idazoxan (alpha-2/I1/I2 antagonist) and prazosin (alpha-1 antagonist)." | 1.29 | Identification, localization and functional analysis of imidazoline and alpha adrenergic receptors in canine prostate. ( Breslin, DS; Ernsberger, P; Felsen, D; Marion, DN; May, M; Nejat, RJ; Nguyen, P; Sutaria, PM; Vaughan, ED, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Michel, MC | 1 |
| Büscher, R | 1 |
| Kerker, J | 1 |
| Kraneis, H | 1 |
| Erdbrügger, W | 1 |
| Brodde, OE | 1 |
| Felsen, D | 1 |
| Ernsberger, P | 1 |
| Sutaria, PM | 1 |
| Nejat, RJ | 1 |
| Nguyen, P | 1 |
| May, M | 1 |
| Breslin, DS | 1 |
| Marion, DN | 1 |
| Vaughan, ED | 1 |
| Muramatsu, I | 1 |
| Oshita, M | 1 |
| Ohmura, T | 1 |
| Kigoshi, S | 1 |
| Akino, H | 1 |
| Gobara, M | 1 |
| Okada, K | 1 |
| Hedlund, H | 1 |
| Andersson, KE | 1 |
| Larsson, B | 1 |
| Purvis, K | 1 |
| Rui, H | 1 |
| Gordeladze, JO | 1 |
| Attramadal, H | 1 |
| Shapiro, E | 1 |
| Lepor, H | 1 |
6 other studies available for clonidine and Prostatic Hyperplasia
| Article | Year |
|---|---|
Alpha 1-adrenoceptor subtype affinities of drugs for the treatment of prostatic hypertrophy. Evidence for heterogeneity of chloroethylclonidine-resistant rat renal alpha 1-adrenoceptor.
Topics: Alkylating Agents; Animals; Centrifugation, Density Gradient; Cerebral Cortex; Clonidine; Drug Resis | 1993 |
Identification, localization and functional analysis of imidazoline and alpha adrenergic receptors in canine prostate.
Topics: Animals; Autoradiography; Azepines; Binding Sites; Clonidine; Dogs; Guanylyl Imidodiphosphate; Imida | 1994 |
Pharmacological characterization of alpha 1-adrenoceptor subtypes in the human prostate: functional and binding studies.
Topics: Adrenergic alpha-Antagonists; Binding, Competitive; Clonidine; Dioxanes; Dose-Response Relationship, | 1994 |
Alpha-adrenoceptors and muscarinic receptors in the isolated human prostate.
Topics: Acetylcholine; Aged; Carbachol; Clonidine; Electric Stimulation; Humans; Male; Middle Aged; Muscle C | 1985 |
Hormonal activation of the adenylyl cyclases of the rat and human prostate gland.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Clonidine; Dopamine; Enzyme Activation; Histamine; Humans; | 1986 |
Alpha 2 adrenergic receptors in hyperplastic human prostate: identification and characterization using [3H] rauwolscine.
Topics: Binding, Competitive; Cerebral Cortex; Clonidine; DNA; Humans; Kinetics; Male; Nordefrin; Prazosin; | 1986 |