clonidine has been researched along with Prader-Willi Syndrome in 3 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
Prader-Willi Syndrome: An autosomal dominant disorder caused by deletion of the proximal long arm of the paternal chromosome 15 (15q11-q13) or by inheritance of both of the pair of chromosomes 15 from the mother (UNIPARENTAL DISOMY) which are imprinted (GENETIC IMPRINTING) and hence silenced. Clinical manifestations include MENTAL RETARDATION; MUSCULAR HYPOTONIA; HYPERPHAGIA; OBESITY; short stature; HYPOGONADISM; STRABISMUS; and HYPERSOMNOLENCE. (Menkes, Textbook of Child Neurology, 5th ed, p229)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Di Giorgio, G | 1 |
| Grugni, G | 1 |
| Fintini, D | 1 |
| Bocchini, S | 1 |
| Spera, S | 1 |
| Cuttini, M | 1 |
| Cappa, M | 1 |
| Crinò, A | 2 |
| Beccaria, L | 2 |
| Benzi, F | 1 |
| Sanzari, A | 1 |
| Bosio, L | 2 |
| Brambilla, P | 1 |
| Chiumello, G | 1 |
| Corrias, A | 1 |
| Bellone, J | 1 |
| Trifirò, G | 1 |
| Livieri, C | 1 |
| Ragusa, L | 1 |
| Salvatoni, A | 1 |
| Andreo, M | 1 |
| Ciampalini, P | 1 |
| Tonini, G | 1 |
2 trials available for clonidine and Prader-Willi Syndrome
| Article | Year |
|---|---|
Growth hormone response to standard provocative stimuli and combined tests in very young children with Prader-Willi syndrome.
Topics: Adrenergic alpha-2 Receptor Agonists; Arginine; Child, Preschool; Cholinesterase Inhibitors; Clonidi | 2014 |
GH/IGF-I axis in Prader-Willi syndrome: evaluation of IGF-I levels and of the somatotroph responsiveness to various provocative stimuli. Genetic Obesity Study Group of Italian Society of Pediatric Endocrinology and Diabetology.
Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Arginine; Child; Child, Preschool; Clonidine; Female; | 2000 |
1 other study available for clonidine and Prader-Willi Syndrome
| Article | Year |
|---|---|
Impairment of growth hormone responsiveness to growth hormone releasing hormone and pyridostigmine in patients affected by Prader-Labhardt-Willi syndrome.
Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Child; Cholinesterase Inhibitors; Clonidine; Female; H | 1996 |