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clonidine and Phobic Disorders

clonidine has been researched along with Phobic Disorders in 13 studies

Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.

Phobic Disorders: Anxiety disorders in which the essential feature is persistent and irrational fear of a specific object, activity, or situation that the individual feels compelled to avoid. The individual recognizes the fear as excessive or unreasonable.

Research Excerpts

ExcerptRelevanceReference
"The growth hormone (GH) response to intravenous administration of clonidine hydrochloride (2 micrograms/kg) was assessed in 16 patients with DSM-III-R social phobia, 13 patients with DSM-III-R panic disorder, and 31 healthy controls."9.07Growth hormone response to intravenous clonidine in social phobia: comparison to patients with panic disorder and healthy volunteers. ( Stein, MB; Tancer, ME; Uhde, TW, 1993)
"The growth hormone (GH) response to intravenous administration of clonidine hydrochloride (2 micrograms/kg) was assessed in 16 patients with DSM-III-R social phobia, 13 patients with DSM-III-R panic disorder, and 31 healthy controls."5.07Growth hormone response to intravenous clonidine in social phobia: comparison to patients with panic disorder and healthy volunteers. ( Stein, MB; Tancer, ME; Uhde, TW, 1993)
"Six subjects with the phobic-anxiety syndrome were treated in a controlled, crossover trial of clonidine hydrochloride v imipramine hydrochloride for periods of four weeks each."5.05Panic-induced elevation of plasma MHPG levels in phobic-anxious patients. Effects of clonidine and imipramine. ( Elsworth, JD; Ko, GN; Leigh, H; Redmond, DE; Rifkin, BG; Roth, RH, 1983)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19908 (61.54)18.7374
1990's2 (15.38)18.2507
2000's3 (23.08)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Collier, TJ1
Greene, JG1
Felten, DL1
Stevens, SY1
Collier, KS1
Valenca, AM1
Mezzasalma, MA1
Nascimento, I1
Lopes, FL1
Zin, WA1
Nardi, AE1
Altesman, RI1
Cole, JO1
Zelnik, TC1
Garcia-Sevilla, JA1
Cameron, OG1
Smith, CB1
Ko, GN1
Elsworth, JD1
Roth, RH1
Rifkin, BG1
Leigh, H1
Redmond, DE1
Campbell, M1
Cueva, JE1
Tancer, ME1
Stein, MB2
Uhde, TW3
Dewar, KM1
Stravynski, A1
Fyer, AJ2
Liebowitz, MR2
Gorman, JM2
Campeas, R1
Levin, A1
Sandberg, D1
Fyer, M1
Hollander, E1
Papp, L1
Goetz, D1
Dillon, D1
Cohen, BS1
Klein, DF1
Vittone, BJ1
Siever, LJ1
Kaye, WH1
Post, RM1
Goldstein, S1

Reviews

2 reviews available for clonidine and Phobic Disorders

ArticleYear
Psychopharmacology in child and adolescent psychiatry: a review of the past seven years. Part II.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1995, Volume: 34, Issue:10

    Topics: Adolescent; Alprazolam; Anticonvulsants; Antipsychotic Agents; Anxiety, Separation; Bipolar Disorder

1995
The quest for biological correlates of social phobia: an interim assessment.
    Acta psychiatrica Scandinavica, 2001, Volume: 103, Issue:4

    Topics: Adrenergic alpha-Agonists; Adult; Animals; Benzodiazepines; Brain; Carbon Dioxide; Clonidine; Epinep

2001

Trials

2 trials available for clonidine and Phobic Disorders

ArticleYear
Panic-induced elevation of plasma MHPG levels in phobic-anxious patients. Effects of clonidine and imipramine.
    Archives of general psychiatry, 1983, Volume: 40, Issue:4

    Topics: Adult; Anxiety Disorders; Clonidine; Double-Blind Method; Fear; Female; Glycols; Humans; Imipramine;

1983
Growth hormone response to intravenous clonidine in social phobia: comparison to patients with panic disorder and healthy volunteers.
    Biological psychiatry, 1993, Nov-01, Volume: 34, Issue:9

    Topics: Adult; Clonidine; Diagnosis, Differential; Double-Blind Method; Female; Growth Hormone; Humans; Infu

1993

Other Studies

9 other studies available for clonidine and Phobic Disorders

ArticleYear
Reduced cortical noradrenergic neurotransmission is associated with increased neophobia and impaired spatial memory in aged rats.
    Neurobiology of aging, 2004, Volume: 25, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aging; Animals

2004
Respiratory panic disorder treatment with clonidine.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2004, Volume: 49, Issue:2

    Topics: Adult; Clonidine; Dose-Response Relationship, Drug; Drug Administration Schedule; Dyspnea; Female; H

2004
Psychopharmacologic treatment of anxiety.
    The Journal of clinical psychiatry, 1983, Volume: 44, Issue:8 Pt 2

    Topics: Adrenergic beta-Antagonists; Anti-Anxiety Agents; Antipsychotic Agents; Anxiety Disorders; Benzodiaz

1983
Clinical response to clonidine and imipramine, and platelet alpha 2-adrenoreceptors in a case of agoraphobia with panic attacks.
    Biological psychiatry, 1982, Volume: 17, Issue:6

    Topics: Adult; Agoraphobia; Blood Platelets; Clonidine; Drug Therapy, Combination; Fear; Humans; Imipramine;

1982
Cortisol response to clonidine in panic disorder: comparison with depressed patients and normal controls.
    Biological psychiatry, 1988, Volume: 24, Issue:3

    Topics: Adult; Agoraphobia; Bipolar Disorder; Clonidine; Depressive Disorder; Fear; Female; Humans; Hydrocor

1988
Effects of clonidine on alprazolam discontinuation in panic patients: a pilot study.
    Journal of clinical psychopharmacology, 1988, Volume: 8, Issue:4

    Topics: Adult; Alprazolam; Clonidine; Female; Humans; Male; Phobic Disorders; Prospective Studies; Psychiatr

1988
Antipanic drug effects during lactate infusion in lactate-refractory panic patients.
    Psychiatry research, 1987, Volume: 21, Issue:3

    Topics: Adult; Agoraphobia; Alprazolam; Clonidine; Desipramine; Fear; Female; Fluoxetine; Humans; Imipramine

1987
Blunted growth hormone response to clonidine in panic disorder patients.
    Biological psychiatry, 1986, Volume: 21, Issue:11

    Topics: Adrenergic Fibers; Adult; Agoraphobia; Antidepressive Agents, Tricyclic; Anxiety Disorders; Brain; C

1986
Treatment of social phobia with clonidine.
    Biological psychiatry, 1987, Volume: 22, Issue:3

    Topics: Adult; Blushing; Clonidine; Humans; Male; Phobic Disorders

1987